mpiBLAST

mpiBLAST is an open-source, parallel implementation of NCBI BLAST, developed by folks at http://www.mpiblast.org/ By efficiently utilizing distributed computational resources through database fragmentation, query segmentation, intelligent scheduling, and parallel I/O, mpiBLAST improves NCBI BLAST performance by several orders of magnitude while scaling to hundreds of processors. mpiBLAST is also portable across many different platforms and operating systems. Lastly, a renewed focus and consolidation of the many codebases has positioned mpiBLAST to continue to be of high utility to the bioinformatics community. More...

Key Features of mpiBLAST:

Manual

http://www.animalgenome.org/bioinfo/resources/manuals/mpiblast.html