format-version: 1.2
date: 19:05:2009 10:47
saved-by: caripark
auto-generated-by: OBO-Edit 2.0
subsetdef: slim_cattle "ATO Cattle Slim"
subsetdef: slim_chkn "ATO Chicken Slim"
subsetdef: slim_pig "ATO Pig Slim"
default-namespace: ATO_namespace

[Term]
id: ATO:0000000
name: Trait
is_obsolete: true

[Term]
id: ATO:0000001
name: Development trait
is_obsolete: true

[Term]
id: ATO:0000002
name: Exterior trait
is_obsolete: true

[Term]
id: ATO:0000003
name: Immune function trait
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_obsolete: true

[Term]
id: ATO:0000004
name: product quality
def: "characteristics related to the ability of a product produced by or obtained from the body of an animal to meet certain standards" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: ID:0000701 ! product trait

[Term]
id: ATO:0000005
name: production trait
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_obsolete: true

[Term]
id: ATO:0000006
name: Reproduction trait
subset: slim_cattle
subset: slim_pig
is_obsolete: true

[Term]
id: ATO:0000007
name: growth
is_obsolete: true

[Term]
id: ATO:0000008
name: physiology
is_obsolete: true

[Term]
id: ID:0000000
name: conformation
def: "characteristics relating to an organism's overall structure and proportions" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
is_a: MT:0005395 ! other trait
created_by: caripark
creation_date: 2008-11-10T10:09:36Z

[Term]
id: ID:0000001
name: pigmentation
subset: slim_cattle
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:09:36Z

[Term]
id: ID:0000002
name: behavioral
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:09:36Z

[Term]
id: ID:0000003
name: defects
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:09:36Z

[Term]
id: ID:0000004
name: age
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:09:36Z

[Term]
id: ID:0000005
name: disease resistance
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:12:53Z

[Term]
id: ID:0000006
name: mastitis
def: "inflammation of the parenchyma of the mammary gland" [CP:Cari Park_Iowa State University curator, MeSH:C17.800.090.968, MeSH:C22.196.581]
subset: slim_cattle
relationship: part_of MT:0001881 ! mammary gland physiology
created_by: caripark
creation_date: 2008-11-10T10:12:53Z

[Term]
id: ID:0000007
name: parasite load
def: "number of parasites harbored by an organism" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: ID:0000675 ! response to parasitic infection
created_by: caripark
creation_date: 2008-11-10T10:12:53Z

[Term]
id: ID:0000008
name: parasite resistance
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:12:53Z

[Term]
id: ID:0000009
name: postchallenge traits
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:12:53Z

[Term]
id: ID:0000010
name: red blood cell mass
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:12:53Z

[Term]
id: ID:0000011
name: immune capacity
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:12:53Z

[Term]
id: ID:0000012
name: pathogen
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:12:53Z

[Term]
id: ID:0000013
name: health other
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:12:53Z

[Term]
id: ID:0000014
name: carcass trait
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:20:24Z

[Term]
id: ID:0000015
name: egg product quality
def: "characteristics related to the ability of an egg to meet certain standards" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: ATO:0000004 ! product quality
created_by: caripark
creation_date: 2008-11-10T10:20:24Z

[Term]
id: ID:0000016
name: meat product quality
def: "characteristics related to the ability of meat products to meet certain standards" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: ATO:0000004 ! product quality
created_by: caripark
creation_date: 2008-11-10T10:20:24Z

[Term]
id: ID:0000017
name: feed intake
def: "Amount of feed consumed" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "feed consumption" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:38:24Z

[Term]
id: ID:0000018
name: lifetime production
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:38:24Z

[Term]
id: ID:0000019
name: milk product quality
def: "characteristics related to the ability of milk to meet certain standards" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_a: ATO:0000004 ! product quality
created_by: caripark
creation_date: 2008-11-10T10:38:24Z

[Term]
id: ID:0000020
name: egg production
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:38:24Z

[Term]
id: ID:0000021
name: production other
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:38:24Z

[Term]
id: ID:0000022
name: digestive organ
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:38:24Z

[Term]
id: ID:0000023
name: feed conversion
def: "measure of an animal's ability to convert feed into additional body mass" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
subset: slim_pig
synonym: "feed efficiency" RELATED []
relationship: part_of MT:0001731 ! postnatal growth rate
relationship: part_of MT:0002121 ! metabolism
created_by: caripark
creation_date: 2008-11-10T10:38:24Z

[Term]
id: ID:0000024
name: endocrine
subset: slim_cattle
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:44:31Z

[Term]
id: ID:0000025
name: fertility
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:44:31Z

[Term]
id: ID:0000026
name: life history
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:44:31Z

[Term]
id: ID:0000027
name: reproductive organ
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:44:31Z

[Term]
id: ID:0000028
name: other reproductive
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T10:44:31Z

[Term]
id: ID:0000029
name: 200 day wean weight
def: "Body weight at weaning (approximately 200 days of age)" [CP:Cari Park_Iowa State University curator]
comment: Cattle trait.
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T12:52:15Z

[Term]
id: ID:0000030
name: body weight (400 days)
def: "Body weight at 400 days of age" [CP:Cari Park_Iowa State University curator]
comment: Cattle trait.
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T12:52:15Z

[Term]
id: ID:0000031
name: adjusted weaning weight
comment: Cattle trait.
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T12:52:15Z

[Term]
id: ID:0000032
name: adjusted yearling weight
comment: Cattle trait.
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T12:52:15Z

[Term]
id: ID:0000033
name: average daily gain
def: "change in body weight over a period of time, divided by the number of days in the period" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
is_a: MT:0001731 ! postnatal growth rate
is_a: MT:0005456 ! weight gain
created_by: caripark
creation_date: 2008-11-10T12:52:15Z

[Term]
id: ID:0000034
name: birth weight
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T12:52:15Z

[Term]
id: ID:0000035
name: BWF scaled by BWI
def: "Relative body weight (final body weight/initial body weight)" [CP:Cari Park_Iowa State University curator]
comment: Cattle trait.
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T12:52:15Z

[Term]
id: ID:0000036
name: body weight (initial)
def: "Body weight at the beginning of a test period" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T12:52:15Z

[Term]
id: ID:0000037
name: lean to fat ratio
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T12:52:15Z

[Term]
id: ID:0000038
name: body weight (mean)
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T12:52:15Z

[Term]
id: ID:0000039
name: post-weaning average daily gain
def: "Average daily change in body weight following weaning" [CP:Cari Park_Iowa State University curator]
comment: Cattle trait.
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T12:52:15Z

[Term]
id: ID:0000040
name: post-weaning daily gain--pasture
def: "Average daily change in body weight following weaning in animals maintained on pasture" [CP:Cari Park_Iowa State University curator]
comment: Cattle trait.
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T12:52:15Z

[Term]
id: ID:0000041
name: pre-weaning average daily gain
def: "Average daily change in body weight from birth to weaning" [CP:Cari Park_Iowa State University curator]
comment: Cattle trait.
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T12:52:15Z

[Term]
id: ID:0000042
name: length of productive life
def: "length of time during which a livestock animal can be utilized for breeding or production" [CP:Cari Park_Iowa State University curator]
comment: In dairy cows, the length of time a female is producing milk, prior to the age of 84 months
subset: slim_cattle
subset: slim_pig
synonym: "functional herd life" EXACT []
synonym: "longevity" RELATED []
is_a: MT:0005372 ! life span/aging trait
created_by: caripark
creation_date: 2008-11-10T02:40:05Z

[Term]
id: ID:0000043
name: weaning weight
comment: Cattle trait.
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T12:52:15Z

[Term]
id: ID:0000044
name: body weight (1 year)
def: "Body weight at 1 year of age" [CP:Cari Park_Iowa State University curator]
comment: Cattle trait.
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T12:52:15Z

[Term]
id: ID:0000045
name: metabolic disorder parameter
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T12:56:21Z

[Term]
id: ID:0000046
name: corticosterone response
def: "Concentration of corticosterone in the blood after manual restraint of a bird.  Used as a measure of acute stress." [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:14:43Z

[Term]
id: ID:0000047
name: circulating creatine kinase level
def: "concentration in the blood of the enzyme creatine kinase, which uses ATP to convert creatine to phosphocreatine and ADP; elevated levels are indicative of muscle damage." [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
subset: slim_pig
synonym: "creatine kinase concentration" EXACT []
is_a: MT:0001570 ! circulating enzyme level
created_by: caripark
creation_date: 2008-11-10T01:14:43Z

[Term]
id: ID:0000048
name: fluid in the heart sac
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:14:43Z

[Term]
id: ID:0000049
name: hematocrit value
synonym: "packed cell volume" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:14:43Z

[Term]
id: ID:0000050
name: liver abnormalities
def: "Liver that is lighter in color, has an abnormal surface texture, or both" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:14:43Z

[Term]
id: ID:0000051
name: mean blood cell volume
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:14:43Z

[Term]
id: ID:0000052
name: packed cell volume
synonym: "hematocrit" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:14:43Z

[Term]
id: ID:0000053
name: plasma concentration of cholesterol
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:14:43Z

[Term]
id: ID:0000054
name: plasma concentration of glucose
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:14:43Z

[Term]
id: ID:0000055
name: circulating insulin-like growth factor level
def: "concentration in the blood of insulin-like growth factor (IGF), a polypeptide hormone similar in sequence to insulin" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
synonym: "plasma concentration of IGF" EXACT []
is_a: MT:0005418 ! circulating hormone level
created_by: caripark
creation_date: 2008-11-10T01:14:43Z

[Term]
id: ID:0000056
name: plasma concentration of insulin
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:14:43Z

[Term]
id: ID:0000057
name: plasma concentration of triglycerides
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:14:43Z

[Term]
id: ID:0000058
name: right ventricular weight as a percentage of body weight
def: "Weight of the right ventricle of the heart divided by total body weight" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:14:43Z

[Term]
id: ID:0000059
name: total heart ventricle morphology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the lower chambers of the heart" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: MT:0005294 ! heart ventricle morphology
created_by: caripark
creation_date: 2008-11-10T01:14:43Z

[Term]
id: ID:0000060
name: troponin T concentration
def: "concentration in the blood of one of a complex of three regulatory proteins required for skeletal and cardiac muscle contraction; used as an indicator for myocardial damage." [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of MT:0002972 ! cardiac muscle contractility
created_by: caripark
creation_date: 2008-11-10T01:14:43Z

[Term]
id: ID:0000061
name: frame score
def: "A numerical rating of cattle skeletal size calculated based on hip height and age.  Indicates the growth pattern and potential mature size of the animal." [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:17:50Z

[Term]
id: ID:0000062
name: chest circumference
def: "circumference of an animal's girth measured posterior to the front legs" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
synonym: "heart girth" EXACT []
relationship: part_of MT:0004134 ! chest morphology
created_by: caripark
creation_date: 2008-11-10T01:17:50Z

[Term]
id: ID:0000063
name: heart length
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:17:50Z

[Term]
id: ID:0000064
name: hip height
def: "height of an animal measured from the ground to a point on the back directly above the hipbones" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
synonym: "height at sacrum" EXACT []
synonym: "stature" RELATED []
is_a: MT:0001253 ! body height
created_by: caripark
creation_date: 2008-11-10T01:17:50Z

[Term]
id: ID:0000065
name: hook height
def: "height of an animal measured from the ground to the point of the hip (tuber sacrale)" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_a: MT:0001253 ! body height
created_by: caripark
creation_date: 2008-11-10T01:17:50Z

[Term]
id: ID:0000066
name: hip width
def: "distance between the points of both hips" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
synonym: "hook width" EXACT []
relationship: part_of MT:0003956 ! body size
created_by: caripark
creation_date: 2008-11-10T01:17:50Z

[Term]
id: ID:0000067
name: udder morphology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the organ in certain species containing two or more mammary glands, each with its own nipple" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_a: MT:0001119 ! female reproductive anatomy
created_by: caripark
creation_date: 2008-11-10T01:17:50Z

[Term]
id: ID:0000068
name: degree of spotting
def: "the proportion of unpigmented skin (white coat color) on an animal's body" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
relationship: part_of ID:0000353 ! spotted coat
created_by: caripark
creation_date: 2008-11-10T01:18:17Z

[Term]
id: ID:0000069
name: percentage decrease in body weight up to day 150 after challenge
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:27:20Z

[Term]
id: ID:0000070
name: white blood cell count
subset: slim_cattle
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:27:53Z

[Term]
id: ID:0000071
name: PTA somatic cell score
def: "Predicted transmitting ability for somatic cell score is a measure used to improve mastitis resistance. Bulls with low PTA are expected to have daughters with lower incidence of mastitis than bulls with high PTA." [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:29:25Z

[Term]
id: ID:0000072
name: somatic cell count in milk
def: "the number of somatic cells (leukocytes) per milliliter of milk; a high count is an indicator of mastitis." [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_a: ID:0000006 ! mastitis
relationship: part_of MT:0004047 ! milk composition
created_by: caripark
creation_date: 2008-11-10T01:29:25Z

[Term]
id: ID:0000073
name: somatic cell score
def: "Transformation of the number of somatic cells in milk, used as an indicator of bacterial infection/mastitis.  SCS=ln(SCC/100,000)+3" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:29:25Z

[Term]
id: ID:0000074
name: parasite detection rate
def: "Number of times parasitic infection is detected in an individual following challenge" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:31:27Z

[Term]
id: ID:0000075
name: parasites-mean of natural logarithm
def: "Mean of natural logarithm (ni + 1), ni = number of parasites detected at day i after challenge" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:31:27Z

[Term]
id: ID:0000076
name: susceptibility to gastrointestinal worms
subset: slim_cattle
synonym: "resistance to gastrointestinal worms" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:32:07Z

[Term]
id: ID:0000077
name: susceptibility to metastrongylus
def: "Likelihood that an organism will develop ill effects from infection with nematodes of the genus Metastrongylus" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
synonym: "resistance to metastrongylus" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:32:07Z

[Term]
id: ID:0000078
name: susceptibility to trypanosomosis
def: "Likelihood that an organism will develop ill effects from infection with parasitic protozoans of the genus Trypanosoma" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
synonym: "resistance to trypanosomosis" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:32:07Z

[Term]
id: ID:0000079
name: final packed red blood cell volume
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:35:08Z

[Term]
id: ID:0000080
name: initial packed red blood cell volume
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:35:08Z

[Term]
id: ID:0000081
name: minimum packed red blood cell volume
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:35:08Z

[Term]
id: ID:0000082
name: packed red blood cell volume
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:35:08Z

[Term]
id: ID:0000083
name: PCV variance
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:35:08Z

[Term]
id: ID:0000084
name: PCVF
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:35:08Z

[Term]
id: ID:0000085
name: PCVF minus PCVM
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:35:08Z

[Term]
id: ID:0000086
name: PCVFM
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:35:08Z

[Term]
id: ID:0000087
name: PCVI
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:35:08Z

[Term]
id: ID:0000088
name: PCVI minus PCVF
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:35:08Z

[Term]
id: ID:0000089
name: PCVI minus PCVM
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:35:08Z

[Term]
id: ID:0000090
name: PCVM
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:35:08Z

[Term]
id: ID:0000091
name: percentage decrease in PCV up to day 100 after challenge
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:35:08Z

[Term]
id: ID:0000092
name: percentage decrease in PCV up to day 150 after challenge
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:35:08Z

[Term]
id: ID:0000093
name: adjusted fat thickness
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:40:23Z

[Term]
id: ID:0000094
name: adjusted mature weight
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:40:23Z

[Term]
id: ID:0000095
name: anatomy
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:40:23Z

[Term]
id: ID:0000096
name: body condition score
def: "Scoring system used to estimate energy reserves (fat and muscle) in beef cows.  Scores are based on fat deposition in relation to skeletal features." [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:40:23Z

[Term]
id: ID:0000097
name: chemical
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:40:23Z

[Term]
id: ID:0000098
name: enzyme activity
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:40:23Z

[Term]
id: ID:0000099
name: fat composition
subset: slim_cattle
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:40:23Z

[Term]
id: ID:0000100
name: fat deposition
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:40:23Z

[Term]
id: ID:0000101
name: fatty acid content
def: "Measure of the fatty acids present in a fat sample" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:40:23Z

[Term]
id: ID:0000102
name: meat flavor
def: "characteristics related to the distinctive taste of meat" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
relationship: part_of ID:0000016 ! meat product quality
created_by: caripark
creation_date: 2008-11-10T01:40:23Z

[Term]
id: ID:0000103
name: mature weight
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:40:23Z

[Term]
id: ID:0000104
name: meat color
def: "characteristics related to the color of meat" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
relationship: part_of ID:0000016 ! meat product quality
created_by: caripark
creation_date: 2008-11-10T01:40:23Z

[Term]
id: ID:0000105
name: muscling
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:40:23Z

[Term]
id: ID:0000106
name: meat odor
def: "characteristics related to the distinctive smell of meat" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
relationship: part_of ID:0000016 ! meat product quality
created_by: caripark
creation_date: 2008-11-10T01:40:23Z

[Term]
id: ID:0000107
name: pH
def: "Measurement of muscle pH following slaughter" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:40:23Z

[Term]
id: ID:0000108
name: stiffening
subset: slim_cattle
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:40:23Z

[Term]
id: ID:0000109
name: meat texture
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
relationship: part_of ID:0000016 ! meat product quality
created_by: caripark
creation_date: 2008-11-10T01:40:23Z

[Term]
id: ID:0000110
name: shear force
def: "Assessment of meat tenderness based on a measurement of the amount of force (kg) required to shear multiple core samples from a cut of meat" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:40:23Z

[Term]
id: ID:0000111
name: bone weight
def: "weight of one or more of the bones of the skeleton" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
relationship: part_of MT:0003795 ! bone structure
created_by: caripark
creation_date: 2008-11-10T01:44:59Z

[Term]
id: ID:0000112
name: bone yield
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:44:59Z

[Term]
id: ID:0000113
name: carcass dressing
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:44:59Z

[Term]
id: ID:0000114
name: carcass weight
def: "weight of a carcass following slaughter and removal of the head, hide, intestinal tract, and internal organs" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0001259 ! body weight
created_by: caripark
creation_date: 2008-11-10T01:44:59Z

[Term]
id: ID:0000115
name: carcass yield
subset: slim_cattle
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:44:59Z

[Term]
id: ID:0000116
name: dressing percentage
def: "The percentage of the live animal that ends up as carcass (=hot carcass weight/body weight at slaughter)" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:44:59Z

[Term]
id: ID:0000117
name: hot carcass weight
def: "hot or un-chilled weight of a carcass following slaughter and removal of the head, hide, intestinal tract, and internal organs" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
is_a: ID:0000114 ! carcass weight
created_by: caripark
creation_date: 2008-11-10T01:44:59Z

[Term]
id: ID:0000118
name: vertebra number
def: "Number of bone segments constituting the spinal column" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:44:59Z

[Term]
id: ID:0000119
name: rib bone fat
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:44:59Z

[Term]
id: ID:0000120
name: rib muscle thickness
def: "distance between the latissimus muscle and pleura membrane measured halfway between the rib ends" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
relationship: part_of MT:0002280 ! intercostal muscle morphology
created_by: caripark
creation_date: 2008-11-10T01:44:59Z

[Term]
id: ID:0000121
name: number of lumbar vertebrae
def: "number of spinal column segments in the loin area, between the ribs and the pelvis" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
relationship: part_of MT:0000138 ! vertebrae number
relationship: part_of MT:0003049 ! lumbar vertebrae morphology
created_by: caripark
creation_date: 2008-11-10T01:45:36Z

[Term]
id: ID:0000122
name: number of thoracic vertebrae
def: "number of segments in the middle of the spinal column, which articulate with the ribs" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
relationship: part_of MT:0000138 ! vertebrae number
relationship: part_of MT:0003047 ! thoracic vertebrae morphology
created_by: caripark
creation_date: 2008-11-10T01:45:36Z

[Term]
id: ID:0000123
name: USDA yield grade
def: "Grade used to classify carcasses based on the expected yield of trimmed, boneless major retail cuts.  Calculation is based on external fat thickness, hot carcass weight, kidney, pelvic, and heart fat, and loin muscle area." [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:46:56Z

[Term]
id: ID:0000124
name: backfat
def: "Layer of subcutaneous fat over the back of a pig" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
synonym: "fatback" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:50:29Z

[Term]
id: ID:0000125
name: fat depth
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:50:29Z

[Term]
id: ID:0000126
name: fat thickness
def: "the thickness of a layer of adipose tissue" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
synonym: "fat depth" EXACT []
is_a: MT:0005452 ! body fat amount
created_by: caripark
creation_date: 2008-11-10T01:50:29Z

[Term]
id: ID:0000127
name: fat trim yield
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:50:29Z

[Term]
id: ID:0000128
name: fat weight
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:50:29Z

[Term]
id: ID:0000129
name: fat yield
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:50:29Z

[Term]
id: ID:0000130
name: kidney, pelvic, and heart fat weight
def: "weight of fat in the body cavity, specifically in the areas of the kidneys, pelvis, and heart" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
synonym: "internal fat" EXACT []
is_a: MT:0001781 ! white fat amount
created_by: caripark
creation_date: 2008-11-10T01:50:29Z

[Term]
id: ID:0000131
name: marbling
def: "visible intramuscular fat" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
relationship: part_of ID:0000016 ! meat product quality
relationship: part_of MT:0000013 ! fat distribution
created_by: caripark
creation_date: 2008-11-10T01:50:29Z

[Term]
id: ID:0000132
name: retail product yield
def: "yield of trimmed retail cuts obtained from a carcass" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_a: ID:0000714 ! product weight
created_by: caripark
creation_date: 2008-11-10T01:50:29Z

[Term]
id: ID:0000133
name: rib fat weight
def: "weight of fat dissected from a wholesale rib cut" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_a: MT:0001781 ! white fat amount
created_by: caripark
creation_date: 2008-11-10T01:50:29Z

[Term]
id: ID:0000134
name: subcutaneous fat
def: "layer of fat lying directly beneath the skin" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
relationship: part_of MT:0000013 ! fat distribution
created_by: caripark
creation_date: 2008-11-10T01:50:29Z

[Term]
id: ID:0000135
name: subcutaneous fat thickness
def: "thickness of the fat layer directly beneath the skin" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
is_a: ID:0000126 ! fat thickness
relationship: part_of ID:0000134 ! subcutaneous fat
created_by: caripark
creation_date: 2008-11-10T01:50:57Z

[Term]
id: ID:0000136
name: adjusted subcutaneous fat thickness between 12th and 13th ribs
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:50:57Z

[Term]
id: ID:0000137
name: back subcutaneous fat thickness
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:56:01Z

[Term]
id: ID:0000138
name: forebelly subcutaneous fat thickness
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:56:01Z

[Term]
id: ID:0000139
name: hind belly subcutaneous fat thickness
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:56:01Z

[Term]
id: ID:0000140
name: loin subcutaneous fat thickness
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:56:01Z

[Term]
id: ID:0000141
name: middle belly subcutaneous fat thickness
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:56:01Z

[Term]
id: ID:0000142
name: shoulder subcutaneous fat thickness
def: "Thickness of the subcutaneous fat on the upper portion of the front leg" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
synonym: "fat depth at shoulder" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:56:01Z

[Term]
id: ID:0000143
name: % USDA choice
def: "Percentage of animals receiving a USDA quality grade of Choice or higher, based on expected palatability.  Grade is based on degree of marbling and animal's physiological age (maturity)" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:59:03Z

[Term]
id: ID:0000144
name: double muscling
def: "Condition caused by mutation of the myostatin (GDF8) gene, which results in significant skeletal muscle hyperplasia and decreased fat deposition" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:59:03Z

[Term]
id: ID:0000145
name: hindquarter muscle weight
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:59:03Z

[Term]
id: ID:0000146
name: longissimus dorsi weight
def: "weight of the longissimus dorsi" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
synonym: "loin weight" EXACT []
synonym: "longissimus muscle weight" EXACT []
is_a: ID:0000706 ! longissimus dorsi morphology
is_a: ID:0000712 ! skeletal muscle weight
created_by: caripark
creation_date: 2008-11-10T01:59:03Z

[Term]
id: ID:0000147
name: longissimus muscle area
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:59:03Z

[Term]
id: ID:0000148
name: rib eye area
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T01:59:03Z

[Term]
id: ID:0000149
name: rib muscle weight
def: "weight of muscle tissue obtained from a wholesale rib cut" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
relationship: part_of MT:0002280 ! intercostal muscle morphology
created_by: caripark
creation_date: 2008-11-10T01:59:03Z

[Term]
id: ID:0000150
name: Warner-Bratzler shear force
def: "Measurement of shear force with precisely defined equipment and sample specifications, including cutting blade thickness, shape, and bevel, and diameter of sample cores" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-12-09T01:53:27Z

[Term]
id: ID:0000151
name: LMA
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:40:05Z

[Term]
id: ID:0000152
name: overall wellness/fitness
def: "a measure of the overall healthfulness of an organism, in relation to the frequency with which medical care is required" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
synonym: "veterinary treatments" NARROW []
is_a: MT:0005395 ! other trait
created_by: caripark
creation_date: 2008-11-10T02:40:05Z

[Term]
id: ID:0000153
name: milk fat
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:40:37Z

[Term]
id: ID:0000154
name: milk protein
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:40:37Z

[Term]
id: ID:0000155
name: milk yield
def: "amount of milk produced over a given period of time by a lactating mammal" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_a: ID:0000701 ! product trait
created_by: caripark
creation_date: 2008-11-10T02:40:37Z

[Term]
id: ID:0000156
name: daughter deviation % milk fat
def: "Weighted average of the percentage of fat in the milk of a bull's daughters, adjusted for the merit of their dams" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:43:21Z

[Term]
id: ID:0000157
name: daughter deviation milk fat yield
def: "Weighted average of the amount of fat in the milk of a bull's daughters, adjusted for the merit of their dams" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:43:21Z

[Term]
id: ID:0000158
name: milk fat content
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:43:21Z

[Term]
id: ID:0000159
name: milk fat percentage
def: "The percentage of a cow's milk that is made up of fat" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
synonym: "milk fat content" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:43:21Z

[Term]
id: ID:0000160
name: milk fat thickness
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:43:21Z

[Term]
id: ID:0000161
name: milk fat content
def: "amount of fat in milk" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
synonym: "milk fat yield" EXACT []
relationship: part_of ID:0000019 ! milk product quality
relationship: part_of MT:0004047 ! milk composition
created_by: caripark
creation_date: 2008-11-10T02:43:21Z

[Term]
id: ID:0000162
name: daughter deviation % milk protein
def: "Weighted average of the percentage of protein in the milk of a bull's daughters, adjusted for the merit of their dams" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:45:00Z

[Term]
id: ID:0000163
name: daughter deviation milk protein yield
def: "Weighted average of the amount of protein in the milk of a bull's daughters, adjusted for the merit of their dams" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:45:00Z

[Term]
id: ID:0000164
name: milk protein percentage
def: "Percentage of milk that is made up of protein" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:45:00Z

[Term]
id: ID:0000165
name: milk protein content
def: "amount of protein in milk" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
synonym: "milk protein yield" EXACT []
relationship: part_of ID:0000019 ! milk product quality
relationship: part_of MT:0004047 ! milk composition
created_by: caripark
creation_date: 2008-11-10T02:45:00Z

[Term]
id: ID:0000166
name: PTA % milk protein
def: "Predicted transmitting ability for the percentage of milk made up of protein (takes into account information from both parents and progeny)" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:45:00Z

[Term]
id: ID:0000167
name: 305 days milk yield
def: "Amount of milk produced by a cow over a 305 day lactation period" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:46:06Z

[Term]
id: ID:0000168
name: 3rd year total milk yield
def: "Total milk produced by a cow during her third lactation" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:46:06Z

[Term]
id: ID:0000169
name: 5th year total milk yield
def: "Total milk produced by a cow during her fifth lactation" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:46:06Z

[Term]
id: ID:0000170
name: average daily milk yield
def: "Average amount of milk produced per day by a cow" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:46:06Z

[Term]
id: ID:0000171
name: milk yield-other
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:46:06Z

[Term]
id: ID:0000172
name: follicle stimulating hormone
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:50:56Z

[Term]
id: ID:0000173
name: gonadrotropin releasing hormone level
def: "level of the peptide hormone that is produced in the hypothalamus and stimulates the release of follicle stimulating hormone and leutenizing hormone from the anterior pituitary gland" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_chkn
synonym: "leutenizing hormone releasing hormone level" EXACT []
is_a: MT:0003953 ! hormone level
created_by: caripark
creation_date: 2008-11-10T02:50:56Z

[Term]
id: ID:0000174
name: luteinizing hormone
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:50:56Z

[Term]
id: ID:0000175
name: progesterone
subset: slim_cattle
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:50:56Z

[Term]
id: ID:0000176
name: prostaglandins
subset: slim_cattle
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:50:56Z

[Term]
id: ID:0000177
name: 56 days non-return rate
def: "The proportion of females that must be re-bred within 56 days following insemination." [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000178
name: 90 days non-return rate
def: "The proportion of females that must be re-bred within 90 days following insemination." [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000179
name: abortions
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000180
name: offspring mortality rate
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000181
name: offspring born alive
def: "number of offspring, not including stillborn" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
synonym: "prenatal survival" EXACT []
synonym: "total number born alive" EXACT []
relationship: part_of MT:0002161 ! fertility/fecundity
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000182
name: offspring born alive, %
def: "Percentage of offspring born alive (not stillborn)" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000183
name: offspring weaned
def: "number of offspring that survive to weaning" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
synonym: "% survival to weaning" EXACT []
relationship: part_of MT:0002161 ! fertility/fecundity
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000184
name: delivery ease
def: "tendency of an animal to have more or fewer problems at delivery than average" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
relationship: part_of MT:0002907 ! parturition
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000185
name: birthing interval
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000186
name: conception rate
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000187
name: dystocia
def: "difficult labor or delivery" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
relationship: part_of MT:0002907 ! parturition
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000188
name: early fetal abortion rate
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000189
name: offspring born
def: "total number born, including stillborn animals" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
synonym: "total number born" EXACT []
relationship: part_of MT:0002161 ! fertility/fecundity
created_by: caripark
creation_date: 2008-12-10T10:22:09Z

[Term]
id: ID:0000190
name: oestrus intensity
def: "the ability of the female to display oestrus" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
synonym: "heat intensity" EXACT []
relationship: part_of MT:0001927 ! oestrous cycle (sensu Rodentia)
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000191
name: hydrops
def: "Accumulation of fluid (edema) in the fetus" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
synonym: "hydrops fetalis" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000192
name: inseminations per service period
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000193
name: ovulation rate
def: "frequency of ovulation, as determined by the number of corpora lutea in the ovary" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
relationship: part_of MT:0001928 ! ovulation
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000194
name: parity of dam
def: "Number of times a dam has given birth" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000195
name: pregnancy rate
def: "measure of the ability of a female to become pregnant" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
synonym: "conception rate" EXACT []
synonym: "non-return rate" EXACT []
relationship: part_of MT:0001921 ! fertility
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000196
name: non-return rate
def: "Proportion of females that must be re-bred following insemination" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-12-16T02:50:41Z

[Term]
id: ID:0000197
name: stillbirth
def: "offspring that are either born dead or die within 24 hours of birth" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
relationship: part_of MT:0002161 ! fertility/fecundity
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000198
name: time of conception
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000199
name: twinning rate
def: "production of two offspring from a single pregnancy" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
relationship: part_of MT:0002161 ! fertility/fecundity
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000200
name: type of birth
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T02:59:38Z

[Term]
id: ID:0000201
name: development time
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T03:00:43Z

[Term]
id: ID:0000202
name: PTA type
def: "An estimate of the genetic superiority for conformation that a bull will transmit to its offspring" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T03:00:43Z

[Term]
id: ID:0000203
name: female measurements
subset: slim_cattle
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T03:01:22Z

[Term]
id: ID:0000204
name: male measurements
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T03:01:22Z

[Term]
id: ID:0000205
name: teat length
def: "average length of the teats" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_a: MT:0006078 ! nipple morphology
created_by: caripark
creation_date: 2008-11-10T03:02:18Z

[Term]
id: ID:0000206
name: teat number
def: "total number of teats/nipples on a female" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
synonym: "nipple number" EXACT []
is_a: MT:0006078 ! nipple morphology
created_by: caripark
creation_date: 2008-11-10T03:02:18Z

[Term]
id: ID:0000207
name: accessory sperm
def: "additional spermatazoa retained in the zona pellucida of the oocyte after penetration of the first sperm during fertilization" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_chkn
is_a: MT:0005410 ! fertilization
created_by: caripark
creation_date: 2008-11-10T03:03:07Z

[Term]
id: ID:0000208
name: retrograde sperm
def: "sperm that migrate back into the vagina following intrauterine insemination" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
relationship: part_of MT:0005410 ! fertilization
created_by: caripark
creation_date: 2008-11-10T03:03:07Z

[Term]
id: ID:0000209
name: retrograde sperm loss
subset: slim_cattle
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T03:03:07Z

[Term]
id: ID:0000210
name: scrotal circumference
def: "circumference of the external sac of skin that encloses the testes" [ISBN:0-683-40008-8 Stedman's Medical Dictionary\, 27th edition]
subset: slim_cattle
relationship: part_of MT:0002669 ! scrotum morphology
created_by: caripark
creation_date: 2008-11-10T03:03:07Z

[Term]
id: ID:0000211
name: sex drive
subset: slim_cattle
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T03:03:07Z

[Term]
id: ID:0000212
name: sperm activity score
subset: slim_cattle
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T03:03:07Z

[Term]
id: ID:0000213
name: sperm counts
subset: slim_cattle
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T03:03:07Z

[Term]
id: ID:0000214
name: sperm quality
subset: slim_cattle
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T03:03:07Z

[Term]
id: ID:0000215
name: % survival to weaning
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T03:04:56Z

[Term]
id: ID:0000216
name: birth assistance
def: "necessity of assistance during delivery of offspring" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
relationship: part_of MT:0002907 ! parturition
created_by: caripark
creation_date: 2008-11-10T03:04:56Z

[Term]
id: ID:0000217
name: age at first breeding
subset: slim_cattle
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T03:04:56Z

[Term]
id: ID:0000218
name: age at puberty
subset: slim_cattle
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T03:04:56Z

[Term]
id: ID:0000219
name: structural soundness
def: "Soundness of legs, feet, penis, and prepuce" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T03:04:56Z

[Term]
id: ID:0000220
name: abdominal fat weight
def: "weight of the fat lining the abdominal cavity and surrounding the kidneys" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "leaf fat weight" EXACT []
is_a: MT:0001781 ! white fat amount
created_by: caripark
creation_date: 2008-11-10T03:41:26Z

[Term]
id: ID:0000221
name: body weight (5 weeks)
def: "Body weight at 5 weeks of age" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T03:42:21Z

[Term]
id: ID:0000222
name: body weight
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T03:43:30Z

[Term]
id: ID:0000223
name: pectoral muscle weight
def: "combined weight of the pectoralis major and pectoralis minor" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
synonym: "breast muscle weight" EXACT []
is_a: ID:0000712 ! skeletal muscle weight
relationship: part_of MT:0003346 ! pectoral muscle morphology
created_by: caripark
creation_date: 2008-11-10T03:45:54Z

[Term]
id: ID:0000224
name: bursa of Fabricius weight
def: "weight of an epithelial outgrowth of the cloaca in birds where B-lymphocyte maturation occurs" [CP:Cari Park_Iowa State University curator, MeSH:A10.549.175]
subset: slim_chkn
relationship: part_of ID:0000668 ! bursa of Fabricius size
created_by: caripark
creation_date: 2008-11-10T03:45:54Z

[Term]
id: ID:0000225
name: drumstick weight
def: "weight of the hindlimb of a bird, consisting of the tibia and the surrounding meat and skin" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: ID:0000714 ! product weight
relationship: part_of ID:0000689 ! hindlimb weight
created_by: caripark
creation_date: 2008-11-10T03:45:54Z

[Term]
id: ID:0000226
name: gizzard weight
def: "weight of the secondary, muscular stomach in some animals used for grinding up food" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000667 ! gizzard morphology
created_by: caripark
creation_date: 2008-11-10T03:45:54Z

[Term]
id: ID:0000227
name: heart weight
def: "Weight of the organ that pumps blood throughout the body" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T03:45:54Z

[Term]
id: ID:0000228
name: intestine length
def: "Length of the digestive tract" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T03:45:54Z

[Term]
id: ID:0000229
name: liver weight
def: "Weight of the liver removed from a carcass" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T03:45:54Z

[Term]
id: ID:0000230
name: lung weight
def: "Weight of the lung removed from a carcass" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T03:45:54Z

[Term]
id: ID:0000231
name: shank weight
def: "Weight of the part of the leg between the claw and the first joint" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T03:45:54Z

[Term]
id: ID:0000232
name: skin fat weight
def: "Weight of skin plus attached fat obtained from the breast, leg, and thigh of a chicken" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-10T03:45:54Z

[Term]
id: ID:0000233
name: spleen weight
def: "weight of the spleen" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of MT:0002224 ! spleen size
created_by: caripark
creation_date: 2008-11-10T03:45:54Z

[Term]
id: ID:0000234
name: thigh muscle weight
def: "weight of the muscle tissue surrounding the femur of the chicken" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: ID:0000712 ! skeletal muscle weight
relationship: part_of ID:0000235 ! thigh weight
created_by: caripark
creation_date: 2008-11-10T03:45:54Z

[Term]
id: ID:0000235
name: thigh weight
def: "weight of the part of the chicken consisting of the femur and surrounding meat and skin." [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: ID:0000714 ! product weight
relationship: part_of ID:0000689 ! hindlimb weight
created_by: caripark
creation_date: 2008-11-10T03:45:54Z

[Term]
id: ID:0000236
name: weight of the front half of the carcass
def: "weight of the front section of the chicken carcass that results when the whole bird is cut perpendicular to the spine at the ilium, just above the femur; it consists of the entire breast, the adjacent back and ribs, and both wings." [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000114 ! carcass weight
created_by: caripark
creation_date: 2008-11-10T03:45:54Z

[Term]
id: ID:0000237
name: wing weight
def: "weight of the forelimb of a bird, consisting of the humerus, radius, ulna, and metacarpus, and all associated muscle and skin" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: ID:0000687 ! forelimb weight
is_a: ID:0000714 ! product weight
created_by: caripark
creation_date: 2008-11-10T03:45:54Z

[Term]
id: ID:0000238
name: feathering
def: "initial appearance and growth of feathers on young birds" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000664 ! feather morphology
created_by: caripark
creation_date: 2008-11-10T03:46:33Z

[Term]
id: ID:0000239
name: drumstick muscle weight
def: "weight of the muscle tissue surrounding the tibia of the chicken" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: ID:0000712 ! skeletal muscle weight
relationship: part_of ID:0000225 ! drumstick weight
created_by: caripark
creation_date: 2008-11-10T03:56:45Z

[Term]
id: ID:0000240
name: contrafreeloading
def: "to search for food, even though food is readily available" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: MT:0001432 ! food preference
created_by: caripark
creation_date: 2008-11-11T09:38:27Z

[Term]
id: ID:0000241
name: fear-related behavior
def: "behavior observed in response to perceived danger" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: MT:0002572 ! emotion/affect behavior
created_by: caripark
creation_date: 2008-11-11T09:38:27Z

[Term]
id: ID:0000242
name: feather pecking
def: "gentle, forceful, or aggressive pecking of the other birds in an enclosure" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: MT:0002557 ! social/conspecific interaction
created_by: caripark
creation_date: 2008-11-11T09:38:27Z

[Term]
id: ID:0000243
name: receiving feather pecking
def: "a bird is the recipient of gentle, forceful, or aggressive pecking by the other birds in an enclosure" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: MT:0002557 ! social/conspecific interaction
created_by: caripark
creation_date: 2008-11-11T09:38:27Z

[Term]
id: ID:0000244
name: social tendency
def: "Tendency to choose freely available food or food in combination with social stimuli in a maze test with several options" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: MT:0002557 ! social/conspecific interaction
created_by: caripark
creation_date: 2008-11-11T09:38:27Z

[Term]
id: ID:0000245
name: antibody response to x
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T09:47:36Z

[Term]
id: ID:0000246
name: bacteria count in cecum
def: "bacterial count (cfu) in the outpouching(s) of the large intestine below the entrance of the small intestine" [CP:Cari Park_Iowa State University curator, MeSH:A03.556.124.526.209]
subset: slim_chkn
is_a: ID:0000665 ! bacteria count
created_by: caripark
creation_date: 2008-11-11T09:47:36Z

[Term]
id: ID:0000247
name: bacteria count in cloaca
def: "bacterial count (cfu) in the common cavity into which the intestinal, genital, and urinary tracts open in some species" [CP:Cari Park_Iowa State University curator, ISBN:9780618701728]
subset: slim_chkn
is_a: ID:0000665 ! bacteria count
created_by: caripark
creation_date: 2008-11-11T09:47:36Z

[Term]
id: ID:0000248
name: Marek's disease-related traits
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T09:47:36Z

[Term]
id: ID:0000249
name: oocyst shedding
def: "presence in the feces of the encapsulated zygote stage of certain protozoans" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: ID:0000675 ! response to parasitic infection
created_by: caripark
creation_date: 2008-11-11T09:47:36Z

[Term]
id: ID:0000250
name: spleen bacterial burden after challenging with y
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T09:47:36Z

[Term]
id: ID:0000251
name: time to achieve maximum antibody response
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T09:47:36Z

[Term]
id: ID:0000252
name: total mortality
def: "Ability of an individual to survive until the end of an experiment" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T09:48:43Z

[Term]
id: ID:0000253
name: egg albumen height
def: "height of the inner thick albumen (egg white) when an egg is broken onto a flat surface" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000695 ! egg albumen morphology
created_by: caripark
creation_date: 2008-11-11T09:55:05Z

[Term]
id: ID:0000254
name: egg albumen weight
def: "weight of the egg white (weight of the entire egg minus weights of the yolk and shell)" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000577 ! egg weight
relationship: part_of ID:0000695 ! egg albumen morphology
created_by: caripark
creation_date: 2008-11-11T09:55:05Z

[Term]
id: ID:0000255
name: egg shell color
def: "objective measurements of egg shell color" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000696 ! egg shell morphology
created_by: caripark
creation_date: 2008-11-11T09:55:05Z

[Term]
id: ID:0000256
name: egg shell percentage
def: "Percentage of the mass of an egg comprised of shell ([shell weight/total weight] x100)" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T09:55:05Z

[Term]
id: ID:0000257
name: egg shell shape
def: "the ratio of the width of the egg at its widest point to its length at the longest point" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000696 ! egg shell morphology
created_by: caripark
creation_date: 2008-11-11T09:55:05Z

[Term]
id: ID:0000258
name: egg shell strength
def: "a measure of the force required to fracture the shell of an egg" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000698 ! egg shell physiology
created_by: caripark
creation_date: 2008-11-11T09:55:05Z

[Term]
id: ID:0000259
name: egg shell thickness
def: "thickness of the exterior shell of an egg" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000696 ! egg shell morphology
created_by: caripark
creation_date: 2008-11-11T09:55:05Z

[Term]
id: ID:0000260
name: egg shell weight
def: "weight of the rinsed and dried egg shell" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000577 ! egg weight
relationship: part_of ID:0000696 ! egg shell morphology
created_by: caripark
creation_date: 2008-11-11T09:55:05Z

[Term]
id: ID:0000261
name: Haugh unit
def: "A measure of the internal quality of an egg, taking into account its weight and the height of the albumen (egg white) surrounding the yolk" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T09:55:05Z

[Term]
id: ID:0000262
name: gravitational constant
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T09:55:05Z

[Term]
id: ID:0000263
name: long length of egg
def: "length of egg from end to end" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000015 ! egg product quality
created_by: caripark
creation_date: 2008-11-11T09:55:05Z

[Term]
id: ID:0000264
name: short length of egg
def: "diameter of egg (shorter dimension)" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000015 ! egg product quality
created_by: caripark
creation_date: 2008-11-11T09:55:05Z

[Term]
id: ID:0000265
name: egg specific gravity
def: "ratio of the weight of an egg to the weight of an equal volume of water; an indicator of eggshell thickness" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000015 ! egg product quality
created_by: caripark
creation_date: 2008-11-11T09:55:05Z

[Term]
id: ID:0000266
name: egg yolk weight
def: "weight of the yolk of an egg" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000577 ! egg weight
relationship: part_of ID:0000697 ! egg yolk morphology
created_by: caripark
creation_date: 2008-11-11T09:55:05Z

[Term]
id: ID:0000267
name: yolk index
def: "The height of the yolk of a broken egg divided by the yolk diameter" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T09:55:05Z

[Term]
id: ID:0000268
name: color of the breast
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T10:15:31Z

[Term]
id: ID:0000269
name: white meat weight
def: "combined weight of the breast (pectoralis major and pectoralis minor) and wing meat; back muscle weight may or may not be included" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: ID:0000714 ! product weight
created_by: caripark
creation_date: 2008-11-11T10:15:31Z

[Term]
id: ID:0000270
name: egg shell redness
def: "chromatic component of egg shell color from green to red (a*)" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000255 ! egg shell color
created_by: caripark
creation_date: 2008-11-11T10:15:31Z

[Term]
id: ID:0000271
name: egg shell lightness
def: "luminance or lightness component of egg shell color (L*)" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000255 ! egg shell color
created_by: caripark
creation_date: 2008-11-11T10:15:31Z

[Term]
id: ID:0000272
name: egg shell yellowness
def: "chromatic component of egg shell color from blue to yellow (b*)" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000255 ! egg shell color
created_by: caripark
creation_date: 2008-11-11T10:15:31Z

[Term]
id: ID:0000273
name: total blood cell count
def: "number of red and white blood cells" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: MT:0002429 ! blood cell morphology/development
created_by: caripark
creation_date: 2008-11-11T10:27:07Z

[Term]
id: ID:0000274
name: bone mineral content
def: "mineral content of a bone, as determined by x-ray densitometric scanning" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of MT:0002896 ! bone mineralization
created_by: caripark
creation_date: 2008-11-11T10:32:08Z

[Term]
id: ID:0000275
name: bone mineral density
def: "The mineral content of a bone, adjusted for the bone's size" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T10:32:08Z

[Term]
id: ID:0000276
name: humerus area
def: "area of the humerus, calculated based on the length and width determined by x-ray densitometric scanning" [CP:Cari Park_Iowa State University curator]
relationship: part_of MT:0005296 ! humerus morphology
created_by: caripark
creation_date: 2008-11-11T10:32:08Z

[Term]
id: ID:0000277
name: humerus bone mineral content
def: "mineral content of the humerus, as determined by x-ray densitometric scanning" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000274 ! bone mineral content
created_by: caripark
creation_date: 2008-11-11T10:32:08Z

[Term]
id: ID:0000278
name: humerus bone density
def: "the mineral content of the humerus, adjusted for the bone's size" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
synonym: "humerus bone mineral density" EXACT []
relationship: part_of MT:0005007 ! bone density
created_by: caripark
creation_date: 2008-11-11T10:32:08Z

[Term]
id: ID:0000279
name: humerus length
def: "Length of the humerus from end to end" [CP:Cari Park_Iowa State University curator]
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T10:32:08Z

[Term]
id: ID:0000280
name: humerus width
def: "width of the humerus halfway between the ends" [CP:Cari Park_Iowa State University curator]
relationship: part_of MT:0005296 ! humerus morphology
created_by: caripark
creation_date: 2008-11-11T10:32:08Z

[Term]
id: ID:0000281
name: tibia area
def: "area of the tibia, calculated based on the length and width determined by x-ray densitometric scanning" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of MT:0000558 ! tibia morphology
created_by: caripark
creation_date: 2008-11-11T10:32:08Z

[Term]
id: ID:0000282
name: tibia bone mineral content
def: "mineral content of the tibia, as determined by x-ray densitometric scanning" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000274 ! bone mineral content
created_by: caripark
creation_date: 2008-11-11T10:32:08Z

[Term]
id: ID:0000283
name: tibia bone density
def: "the mineral content of the tibia, adjusted for the bone's size" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
synonym: "tibia bone mineral density" EXACT []
relationship: part_of MT:0005007 ! bone density
created_by: caripark
creation_date: 2008-11-11T10:32:08Z

[Term]
id: ID:0000284
name: tibia breaking force
def: "the amount of force required to break the tibia in the middle, while it is supported on both ends" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of MT:0001542 ! bone strength
created_by: caripark
creation_date: 2008-11-11T10:32:08Z

[Term]
id: ID:0000285
name: tibia length
def: "Length of the tibia from end to end" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T10:32:08Z

[Term]
id: ID:0000286
name: tibia modulus of elasticity
def: "a measure of the tibia's ability to return to its original shape after force is applied in the center, while the bone is supported on the ends (stress:strain ratio)" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of MT:0001542 ! bone strength
created_by: caripark
creation_date: 2008-11-11T10:32:08Z

[Term]
id: ID:0000287
name: tibia strain
def: "an indicator of the amount of bending the tibia undergoes when force is applied in the center, and the bone is supported at both ends (change in length per unit length of bone)" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of MT:0001542 ! bone strength
created_by: caripark
creation_date: 2008-11-11T10:32:08Z

[Term]
id: ID:0000288
name: tibia stress
def: "force applied to the tibia per unit area" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of MT:0001542 ! bone strength
created_by: caripark
creation_date: 2008-11-11T10:32:08Z

[Term]
id: ID:0000289
name: tibia width
def: "width of the tibia halfway between the ends" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of MT:0000558 ! tibia morphology
created_by: caripark
creation_date: 2008-11-11T10:32:08Z

[Term]
id: ID:0000290
name: age at first egg
def: "Age at which a bird lays its first egg" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T10:43:29Z

[Term]
id: ID:0000291
name: annual egg production
def: "Eggs laid by a bird in a year" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T10:43:29Z

[Term]
id: ID:0000292
name: egg production rate
def: "number of eggs laid by a bird divided by the number of days over which they are produced" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
synonym: "eggs laid per day" EXACT []
is_a: ID:0000701 ! product trait
created_by: caripark
creation_date: 2008-11-11T10:43:29Z

[Term]
id: ID:0000293
name: egg weight
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T10:43:29Z

[Term]
id: ID:0000294
name: number of eggs produced
def: "number of eggs produced over a given period of time" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: ID:0000701 ! product trait
created_by: caripark
creation_date: 2008-11-11T10:43:29Z

[Term]
id: ID:0000295
name: sum of the eggs laid by a bird
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T10:43:29Z

[Term]
id: ID:0000296
name: body weight (final)
def: "Animal's body weight at the end of a defined test period" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
synonym: "test end body weight" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T10:43:29Z

[Term]
id: ID:0000297
name: feed efficiency
def: "Ratio of body weight gain to amount of feed consumed" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T10:46:34Z

[Term]
id: ID:0000298
name: conformation score
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T10:50:00Z

[Term]
id: ID:0000299
name: weight loss during transport
def: "difference in body weight before and after transport" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: MT:0001263 ! weight loss
created_by: caripark
creation_date: 2008-11-11T10:51:51Z

[Term]
id: ID:0000300
name: average daily gain (10-22 weeks)
def: "Average daily change in body weight from 10 to 22 weeks of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000301
name: average daily gain (18-26 weeks)
def: "Average daily change in body weight from 18 to 26 weeks of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000302
name: average daily gain (3-5 weeks)
def: "Average daily change in body weight from 3 to 5 weeks of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000303
name: average daily gain (3-10 weeks)
def: "Average daily change in body weight from 3 to 10 weeks of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000304
name: average daily gain (4-13 weeks)
def: "Average daily change in body weight from 4 to 13 weeks of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000305
name: average daily gain (5-7 weeks)
def: "Average daily change in body weight from 5 to 7 weeks of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000306
name: average daily gain (60-160 days)
def: "Average daily change in body weight from 60 to 160 days of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000307
name: average daily gain (7-9 weeks)
def: "Average daily change in body weight from 7 to 9 weeks of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000308
name: average daily gain (8-18 weeks)
def: "Average daily change in body weight from 8 to 18 weeks of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000309
name: average daily gain (birth to 3 weeks)
def: "Average daily change in body weight from birth to 3 weeks of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000310
name: average daily gain (birth to 60 days)
def: "Average daily change in body weight from birth to 60 days of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000311
name: average daily gain (25-90 kg)
def: "Average daily change in body weight between the weights of 25 and 90 kg" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000312
name: average daily gain (35-55 kg)
def: "Average daily change in body weight between the weights of 35 and 55 kg" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000313
name: average daily gain (55-80 kg)
def: "Average daily change in body weight between the weights of 55 and 80 kg" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000314
name: average daily gain (birth to 30 kg)
def: "Average daily change in body weight from birth to 30 kg" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000315
name: average daily gain (birth to 70 kg)
def: "Average daily change in body weight from birth to 70 kg" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000316
name: average daily gain (birth to end of test)
def: "Average daily change in body weight from birth to the end of a test period" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000317
name: average daily gain (entire life)
def: "Average daily change in body weight from birth to slaughter" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000318
name: average daily gain on test
def: "Average daily change in body weight during a test period" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000319
name: average daily gain on weaning
def: "Average daily change in body weight from birth to weaning" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
synonym: "pre-weaning average daily gain" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000320
name: average daily gain (weaning to 25 kg)
def: "Average daily change in body weight from weaning to 25 kg" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000321
name: average daily gain (weaning to 55 kg)
def: "Average daily change in body weight from weaning to 55 kg" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:42:29Z

[Term]
id: ID:0000322
name: age at slaughter
def: "age of an animal at the time of slaughter" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0001661 ! life span
created_by: caripark
creation_date: 2008-11-11T12:43:08Z

[Term]
id: ID:0000323
name: body weight (10 weeks)
def: "Body weight at 10 weeks of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:48:27Z

[Term]
id: ID:0000324
name: body weight (13 weeks)
def: "Body weight at 13 weeks of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:48:27Z

[Term]
id: ID:0000325
name: body weight (16 days)
def: "Body weight at 16 days of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:48:27Z

[Term]
id: ID:0000326
name: body weight (17 weeks)
def: "Body weight at 17 weeks of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:48:27Z

[Term]
id: ID:0000327
name: body weight (21 days)
def: "Body weight at 21 days of age" [CP:Cari Park_Iowa State University curator]
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:48:27Z

[Term]
id: ID:0000328
name: body weight (22 weeks)
def: "Body weight at 22 weeks of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:48:27Z

[Term]
id: ID:0000329
name: body weight (25 weeks)
def: "Body weight at 25 weeks of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:48:27Z

[Term]
id: ID:0000330
name: body weight (26 weeks)
def: "Body weight at 26 weeks of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:48:27Z

[Term]
id: ID:0000331
name: body weight (3 weeks)
def: "Body weight at 3 weeks of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:48:27Z

[Term]
id: ID:0000332
name: body weight (30 days)
def: "Body weight at 30 days of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:48:27Z

[Term]
id: ID:0000333
name: body weight (35 days)
def: "Body weight at 35 days of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:48:27Z

[Term]
id: ID:0000334
name: body weight (4 weeks)
def: "Body weight at 4 weeks of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:48:27Z

[Term]
id: ID:0000335
name: body weight (60 days)
def: "Body weight at 60 days of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:48:27Z

[Term]
id: ID:0000336
name: body weight (8 weeks)
def: "Body weight at 8 weeks of age" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:48:27Z

[Term]
id: ID:0000337
name: body weight (birth)
def: "Body weight at birth" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
synonym: "birth weight" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:48:27Z

[Term]
id: ID:0000338
name: body weight (slaughter)
def: "Body weight at slaughter" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:48:27Z

[Term]
id: ID:0000339
name: body weight (weaning)
def: "Body weight at weaning" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
synonym: "weaning weight" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:48:27Z

[Term]
id: ID:0000340
name: longevity
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:52:40Z

[Term]
id: ID:0000341
name: basal circulating adrenocorticotropin level
def: "level of pituitary adrenocorticotropic hormone in the blood in the absence of an external intervention" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0002664 ! circulating adrenocorticotropin level
created_by: caripark
creation_date: 2008-11-11T12:58:57Z

[Term]
id: ID:0000342
name: post-stress ACTH level
def: "Level of pituitary adrenocorticotropic hormone in the blood at the end of a stress test" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:58:57Z

[Term]
id: ID:0000343
name: basal circulating cortisol level
def: "level of cortisol in the blood in the absence of external intervention" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "basal circulating hydrocortisone level" EXACT []
is_a: ID:0000670 ! circulating cortisol level
created_by: caripark
creation_date: 2008-11-11T12:58:57Z

[Term]
id: ID:0000344
name: basal circulating glucose level
def: "level of glucose in the blood in the absence of external intervention" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0000188 ! circulating glucose level
created_by: caripark
creation_date: 2008-11-11T12:58:57Z

[Term]
id: ID:0000345
name: exploration
def: "Time spent rooting or sniffing the sides or floor of the arena during a stress test" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:58:57Z

[Term]
id: ID:0000346
name: locomotion
def: "The extent of movement during a stress test, measured by the number of sections (marked on the floor) the animal enters in an unfamiliar area" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:58:57Z

[Term]
id: ID:0000347
name: induced circulating glucose level
def: "level of glucose in the blood in response to an external intervention" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0000188 ! circulating glucose level
created_by: caripark
creation_date: 2008-11-11T12:58:57Z

[Term]
id: ID:0000348
name: glucose level variations
def: "Difference between post-stress and basal levels of glucose in the blood" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T12:58:57Z

[Term]
id: ID:0000349
name: neuroendocrine response
def: "alterations in the levels of adrenocorticotropic hormone, glucose, and cortisol in response to stress" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0002164 ! gland physiology
created_by: caripark
creation_date: 2008-11-11T12:58:57Z

[Term]
id: ID:0000350
name: induced circulating cortisol level
def: "level of cortisol in the blood in response to external intervention" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "induced circulating hydrocortisone level" EXACT []
is_a: ID:0000670 ! circulating cortisol level
created_by: caripark
creation_date: 2008-11-11T12:58:57Z

[Term]
id: ID:0000351
name: black vs. white coat color
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:01:13Z

[Term]
id: ID:0000352
name: white coat color
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:01:13Z

[Term]
id: ID:0000353
name: spotted coat
def: "presence of spots on an animal's coat" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_a: MT:0002075 ! coat color
created_by: caripark
creation_date: 2008-11-11T01:01:13Z

[Term]
id: ID:0000354
name: rhinitis
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:10:14Z

[Term]
id: ID:0000355
name: scrotal hernia
def: "an inguinal hernia that has passed into the scrotum" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0002669 ! scrotum morphology
created_by: caripark
creation_date: 2008-11-11T01:10:14Z

[Term]
id: ID:0000356
name: swelling of joints
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:10:14Z

[Term]
id: ID:0000357
name: joint abnormalities
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:10:14Z

[Term]
id: ID:0000358
name: joint lesions
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:10:14Z

[Term]
id: ID:0000359
name: osteochondrosis
def: "a class of joint diseases characterized by interruption of a bone's blood supply and bone necrosis, followed by bone regrowth" [CP:Cari Park_Iowa State University curator, MeSH:C05.116.821]
subset: slim_pig
relationship: part_of MT:0003795 ! bone structure
created_by: caripark
creation_date: 2008-11-11T01:10:14Z

[Term]
id: ID:0000360
name: body length
def: "Distance along an animal's top line from between the shoulder blades to the end of the rump" [CP:Cari Park_Iowa State University curator]
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000361
name: circumference of cannon bone
def: "circumference of the metacarpal or metatarsal bone, between the knee or hock and the fetlock" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0000550 ! forelimb morphology
relationship: part_of MT:0000556 ! hindlimb morphology
relationship: part_of MT:0003072 ! metatarsal bone morphology
relationship: part_of MT:0003073 ! metacarpal bone morphology
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000362
name: length of claws (front inside)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000363
name: length of claws (front outside)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000364
name: length of claws (hind inside)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000365
name: length of claws (hind outside)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000366
name: feet and legs score
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000367
name: feet score (front)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000368
name: feet score (hind)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000369
name: femur dimensions
def: "measurements relating to the size of the long bone of the thigh" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0000559 ! femur morphology
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000370
name: hair (amount)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000371
name: height
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000372
name: leg length
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000373
name: leg pastern (front)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000374
name: leg pastern (hind)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000375
name: leg score (front)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000376
name: leg score (hind)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000377
name: leg set view
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000378
name: leg torsion (front)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000379
name: leg torsion (hind)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000380
name: leg angularity (front)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000381
name: leg angularity (hind)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000382
name: lob ear
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000383
name: nose score
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:13:23Z

[Term]
id: ID:0000384
name: vertebrae distance
def: "distance from first thoracic to last lumbar vertebra" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0000137 ! vertebrae morphology
created_by: caripark
creation_date: 2008-11-11T01:14:37Z

[Term]
id: ID:0000385
name: total vertebrae number
def: "total number of bone segments constituting the spinal column" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
relationship: part_of MT:0000138 ! vertebrae number
created_by: caripark
creation_date: 2008-11-11T01:16:14Z

[Term]
id: ID:0000386
name: induced circulating IgG level
def: "level of serum immunoglobulin G in response to an external intervention" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0001805 ! circulating IgG level
created_by: caripark
creation_date: 2008-11-11T01:40:12Z

[Term]
id: ID:0000387
name: anti-O149 E. coli IgG level response
def: "Change in serum levels of E. coli O149 IgG following immunization with E. coli antigens" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:40:12Z

[Term]
id: ID:0000388
name: anti-O149 E. coli IgG levels
def: "Level of serum IgG to E. coli O149 antigen" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:40:12Z

[Term]
id: ID:0000389
name: susceptibility to E. coli K88 infection
def: "Likelihood that an organism will develop ill effects from infection with Escherichia coli expressing K88 antigen" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "resistance to E. coli K88 infection" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:40:12Z

[Term]
id: ID:0000390
name: susceptibility to pseudorabies viral infection
def: "Likelihood that an organism will develop ill effects from infection with pseudorabies virus (suid herpesvirus-1, porcine herpesvirus 1)" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "resistance to pseudorabies viral infection" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:40:12Z

[Term]
id: ID:0000391
name: susceptibility to E. coli F18 infection
def: "Susceptibility to infection by F18-positive E. coli due to the expression of ECF18R alleles in the small intestine" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "small intestinal E. coli F18 receptor" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:40:12Z

[Term]
id: ID:0000392
name: conA-induced lymphocyte proliferation
def: "proliferation of lymphocytes upon stimulation with concanavalin A, a lectin isolated from the jack bean, Canavalia ensiformis" [CP:Cari Park_Iowa State University curator, MeSH:D12.776.503.499.500 "National Library of Medicine - Medical Subject Headings"]
subset: slim_pig
is_a: ID:0000393 ! mitogen-induced lymphocyte proliferation
created_by: caripark
creation_date: 2008-11-11T01:50:35Z

[Term]
id: ID:0000393
name: mitogen-induced lymphocyte proliferation
def: "proliferation of lymphocytes upon stimulation with a protein that induces cell division" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: ID:0000661 ! lymphocyte proliferation
created_by: caripark
creation_date: 2008-11-11T01:50:35Z

[Term]
id: ID:0000394
name: pokeweed mitogen (PWM)-induced lymphocyte proliferation
def: "proliferation of lymphocytes upon stimulation with pokeweed mitogen, a lectin isolated from the roots of Phytolacca americana" [CP:Cari Park_Iowa State University curator, MeSH:D12.776.503.499.875 "National Library of Medicine - Medical Subject Headings"]
subset: slim_pig
is_a: ID:0000393 ! mitogen-induced lymphocyte proliferation
created_by: caripark
creation_date: 2008-11-11T01:50:35Z

[Term]
id: ID:0000395
name: post-stress mitogen-induced IL-2 activity
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:50:35Z

[Term]
id: ID:0000396
name: pre-/post-vaccination levels of IgG to K88 antigen
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:50:35Z

[Term]
id: ID:0000397
name: specific IgG response to E. coli O149 antigen
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:50:35Z

[Term]
id: ID:0000398
name: spontaneous lymphocyte proliferation
def: "unstimulated proliferation of lymphocytes" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: ID:0000661 ! lymphocyte proliferation
created_by: caripark
creation_date: 2008-11-11T01:50:35Z

[Term]
id: ID:0000399
name: stress-induced leukocyte proliferation
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:50:35Z

[Term]
id: ID:0000400
name: stress-induced neutrophil number alteration
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:50:35Z

[Term]
id: ID:0000401
name: muscle androstenone level
def: "amount of the testicular steroid androstenone detected in muscle via ELISA or HPLC" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0002106 ! muscle physiology
created_by: caripark
creation_date: 2008-11-11T02:26:46Z

[Term]
id: ID:0000402
name: fecal bacteria count
def: "bacterial count (cfu) in feces" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: ID:0000665 ! bacteria count
created_by: caripark
creation_date: 2008-11-11T01:54:41Z

[Term]
id: ID:0000403
name: salmonella count in feces (day 7 post-infection)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T01:54:41Z

[Term]
id: ID:0000404
name: bacteria count in liver
def: "bacterial count (cfu) in liver" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: ID:0000665 ! bacteria count
created_by: caripark
creation_date: 2008-11-11T01:54:41Z

[Term]
id: ID:0000405
name: bacteria count in spleen
def: "bacterial count (cfu) in spleen" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: ID:0000665 ! bacteria count
created_by: caripark
creation_date: 2008-11-11T01:54:41Z

[Term]
id: ID:0000406
name: cold carcass weight
def: "weight of a carcass that has been chilled overnight following slaughter and removal of the head, hide, intestinal tract, and internal organs" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: ID:0000114 ! carcass weight
created_by: caripark
creation_date: 2008-11-11T01:57:31Z

[Term]
id: ID:0000407
name: belly percentage
def: "Weight of the cut of meat from the underside of the pig divided by the weight of the carcass" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:01:04Z

[Term]
id: ID:0000408
name: belly weight
def: "weight of the cut of meat obtained from the underside of the pig" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: ID:0000714 ! product weight
created_by: caripark
creation_date: 2008-11-11T02:01:04Z

[Term]
id: ID:0000409
name: body mass index
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:01:04Z

[Term]
id: ID:0000410
name: bone percent
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:01:04Z

[Term]
id: ID:0000411
name: carcass length
def: "length of the carcass following removal of the head; typically measured between the first or second cervical vertebra or the first rib and the pelvis" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0001256 ! body length
created_by: caripark
creation_date: 2008-11-11T02:01:04Z

[Term]
id: ID:0000412
name: carcass thickness
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:01:04Z

[Term]
id: ID:0000413
name: glycogen content
def: "Concentration in muscle of the glucose polysaccharide used for short-term energy storage" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:26:46Z

[Term]
id: ID:0000414
name: diaphragm weight
def: "weight of the muscle that separates the thoracic and abdominal cavities" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0002279 ! diaphragm morphology
created_by: caripark
creation_date: 2008-11-11T02:01:04Z

[Term]
id: ID:0000415
name: glycolytic potential
def: "measure of the available glycogen stores in tissue = 2 x ([glycogen]+[glucose]+[glucose-6-phosphate])+[lactate]" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000694 ! muscle glycogen homeostasis
relationship: part_of MT:0005438 ! glycogen homeostasis
created_by: caripark
creation_date: 2008-11-11T02:26:46Z

[Term]
id: ID:0000416
name: estimated carcass lean content
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:01:04Z

[Term]
id: ID:0000417
name: eye muscle depth
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:01:04Z

[Term]
id: ID:0000418
name: fat-cut percentage
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:01:04Z

[Term]
id: ID:0000419
name: total foot weight
def: "weight of the front feet separated from the carcass at the level of the carpal bones, and the hind feet removed at the tibio-tarsal joint" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: ID:0000686 ! paw/hand/foot/hoof weight
created_by: caripark
creation_date: 2008-11-11T02:01:04Z

[Term]
id: ID:0000420
name: head weight
def: "weight of the head, separated from the carcass at the second cervical vertebra" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0000002 ! head size
created_by: caripark
creation_date: 2008-11-11T02:01:04Z

[Term]
id: ID:0000421
name: small intestine length
def: "length of the upper portion of the digestive tract, between the stomach and the large intestine" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0000496 ! small intestine morphology
created_by: caripark
creation_date: 2008-11-11T02:01:04Z

[Term]
id: ID:0000422
name: shoulder weight
def: "weight of the untrimmed cut of meat from the upper portion of the front leg of the pig" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: ID:0000714 ! product weight
relationship: part_of ID:0000687 ! forelimb weight
created_by: caripark
creation_date: 2008-11-11T02:01:04Z

[Term]
id: ID:0000423
name: skin percentage
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:01:04Z

[Term]
id: ID:0000424
name: skin thickness
def: "Thickness of skin on the back, at the midpoint of body length" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:01:04Z

[Term]
id: ID:0000425
name: skin weight
def: "weight of the membranous protective covering of the body; may include closely associated fat" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
subset: slim_pig
relationship: part_of MT:0002060 ! skin morphology
created_by: caripark
creation_date: 2008-11-11T02:01:04Z

[Term]
id: ID:0000426
name: weight of trimmed wholesale product
def: "weight of four major wholesale cuts of the pig (ham, loin, Boston butt, and picnic shoulder), trimmed of fat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: ID:0000714 ! product weight
created_by: caripark
creation_date: 2008-11-11T02:01:04Z

[Term]
id: ID:0000427
name: trimmed wholesale product/live weight
def: "Weight of four major wholesale cuts of the pig (ham, loin, Boston butt, and picnic shoulder) trimmed of fat and adjusted to a constant live weight" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:01:04Z

[Term]
id: ID:0000428
name: carcass fat-free weight
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:01:17Z

[Term]
id: ID:0000429
name: muscle lactate level
def: "concentration in muscle of the compound produced from pyruvate by lactate dehydrogenase" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0002106 ! muscle physiology
created_by: caripark
creation_date: 2008-11-11T02:26:46Z

[Term]
id: ID:0000430
name: muscle cholesterol level
def: "amount of cholesterol present in the total lipid extracted from a muscle" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0003947 ! cholesterol level
relationship: part_of ID:0000479 ! muscle lipid level
created_by: caripark
creation_date: 2008-11-11T02:26:46Z

[Term]
id: ID:0000431
name: muscle indole level
def: "amount of a tryptophan degradation product detected in muscle via HPLC" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0002106 ! muscle physiology
created_by: caripark
creation_date: 2008-11-11T02:26:46Z

[Term]
id: ID:0000432
name: muscle water content
def: "amount of moisture in a muscle sample, determined by the difference in weight before and after oven drying" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0000676 ! water content
is_a: MT:0002106 ! muscle physiology
created_by: caripark
creation_date: 2008-11-11T02:26:46Z

[Term]
id: ID:0000433
name: muscle protein level
def: "total protein content of muscle" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0002106 ! muscle physiology
created_by: caripark
creation_date: 2008-11-11T02:26:46Z

[Term]
id: ID:0000434
name: muscle skatole level
def: "amount of a tryptophan degradation product detected in muscle via HPLC or colorimetric assay" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "3-methyl indole concentration" EXACT []
is_a: MT:0002106 ! muscle physiology
created_by: caripark
creation_date: 2008-11-11T02:26:46Z

[Term]
id: ID:0000435
name: muscle conductivity
def: "ability of muscle to conduct electrical current" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0002106 ! muscle physiology
created_by: caripark
creation_date: 2008-11-11T02:27:18Z

[Term]
id: ID:0000436
name: skeletal muscle conductivity
def: "ability of skeletal muscle to conduct electrical current" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: ID:0000435 ! muscle conductivity
created_by: caripark
creation_date: 2008-11-11T02:29:54Z

[Term]
id: ID:0000437
name: conductivity (45 min post-mortem)
def: "Electrical conductivity of muscle 45 minutes post-mortem" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:29:54Z

[Term]
id: ID:0000438
name: creatine phosphokinase test
def: "Test for the enzyme that catalyzes the conversion of creatine to phosphocreatine.  Elevated levels are an indication of muscle damage." [CP:Cari Park_Iowa State University curator]
synonym: "creatine kinase test" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:33:29Z

[Term]
id: ID:0000439
name: 7-octadecenoic acid percentage
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:37:42Z

[Term]
id: ID:0000440
name: fatty acid carbon chain length
def: "average number of carbon atoms in the fatty acids in a sample, determined by gas chromatography" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0005666 ! adipose tissue physiology
created_by: caripark
creation_date: 2008-11-11T02:37:42Z

[Term]
id: ID:0000441
name: double-bond index
def: "Sum of the percentage of fatty acids in a fat sample with any number of double bonds, multiplied by the number of double bonds, with the total divided by 100" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:37:42Z

[Term]
id: ID:0000442
name: eicosadienoic acid percentage
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:37:42Z

[Term]
id: ID:0000443
name: eicosenoic acid percentage
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:37:42Z

[Term]
id: ID:0000444
name: fat androstenone level
def: "amount of the testicular steroid androstenone detected in fat samples via ELISA" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0005666 ! adipose tissue physiology
created_by: caripark
creation_date: 2008-11-11T02:37:42Z

[Term]
id: ID:0000445
name: heptadecanoic acid percentage
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:37:42Z

[Term]
id: ID:0000446
name: linoleic acid percentage
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:37:42Z

[Term]
id: ID:0000447
name: linolenic acid percentage
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:37:42Z

[Term]
id: ID:0000448
name: myristic acid percentage
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:37:42Z

[Term]
id: ID:0000449
name: oleic acid percentage
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:37:42Z

[Term]
id: ID:0000450
name: palmitic acid percentage
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:37:42Z

[Term]
id: ID:0000451
name: palmitoleic acid percentage
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:37:42Z

[Term]
id: ID:0000452
name: peroxidability index
def: "Calculated from fatty acid percentage of a fat sample: [(% monoenoic x 0.025) + (% dienoic) + (% trienoic x 2) + (% tetraenoic x 4) + (% pentaenoic x 6) + (% hexaenoic x8)]" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:37:42Z

[Term]
id: ID:0000453
name: stearic acid percentage
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:37:42Z

[Term]
id: ID:0000454
name: unsaturated index
def: "Equal to double bond index/percentage of saturated fatty acids in a fat sample" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:37:42Z

[Term]
id: ID:0000455
name: fat androstenone level (100 days of age)
def: "Amount of the testicular steroid androstenone detected in backfat biopsies via ELISA (100 days of age)" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:38:46Z

[Term]
id: ID:0000456
name: fat androstenone level (120 days of age)
def: "Amount of the testicular steroid androstenone detected in backfat biopsies via ELISA (120 days of age)" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:38:46Z

[Term]
id: ID:0000457
name: fat androstenone level (140 days of age)
def: "Amount of the testicular steroid androstenone detected in backfat biopsies via ELISA (140 days of age)" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:38:46Z

[Term]
id: ID:0000458
name: fat androstenone level (160 days of age)
def: "Amount of the testicular steroid androstenone detected in backfat biopsies via ELISA (160 days of age)" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:38:46Z

[Term]
id: ID:0000459
name: abdominal fat
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:41:11Z

[Term]
id: ID:0000460
name: fat area
def: "Area of fat on M. Lattisimus Dorsi between the 13th and 14th ribs" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0000003 ! adipose tissue morphology
created_by: caripark
creation_date: 2008-11-11T02:47:13Z

[Term]
id: ID:0000461
name: fat cuts
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:47:13Z

[Term]
id: ID:0000462
name: fat percentage in carcass
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:47:13Z

[Term]
id: ID:0000463
name: fat ratio (percentage)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:47:13Z

[Term]
id: ID:0000464
name: fat-to-meat ratio
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:47:13Z

[Term]
id: ID:0000465
name: intermuscular fat weight
def: "weight of fat present between the muscles" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "seam fat weight" EXACT []
is_a: MT:0001781 ! white fat amount
created_by: caripark
creation_date: 2008-11-11T02:47:13Z

[Term]
id: ID:0000466
name: internal fat ratio
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:47:13Z

[Term]
id: ID:0000467
name: intestinal fat percent
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:47:13Z

[Term]
id: ID:0000468
name: intestinal fat weight
def: "weight of the fat associated with the small intestine" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "caul fat" EXACT []
is_a: MT:0001781 ! white fat amount
created_by: caripark
creation_date: 2008-11-11T02:47:13Z

[Term]
id: ID:0000469
name: backfat depth
def: "Depth of subcutaneous fat (including skin) at a point on the animal's back" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:58:47Z

[Term]
id: ID:0000470
name: leaf fat percentage
def: "Weight of the fat lining the abdominal cavity and surrounding the kidneys, expressed as a percentage of total carcass weight" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:47:13Z

[Term]
id: ID:0000471
name: leaf fat weight
def: "Weight of the fat lining the abdominal cavity and surrounding the kidneys" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:47:13Z

[Term]
id: ID:0000472
name: subcutaneous fat weight
def: "weight of the fat layer directly under the skin" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0001781 ! white fat amount
relationship: part_of ID:0000134 ! subcutaneous fat
created_by: caripark
creation_date: 2008-11-11T02:48:24Z

[Term]
id: ID:0000473
name: backfat + leaf fat percentage
def: "Sum of subcutaneous backfat and internal fat, expressed as a percentage of total carcass weight" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:47:13Z

[Term]
id: ID:0000474
name: residual fatty acids
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:47:13Z

[Term]
id: ID:0000475
name: shoulder external fat weight
def: "Weight of the fat trimmed from the cut of meat from the upper portion of the front leg" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:47:13Z

[Term]
id: ID:0000476
name: shoulder fat depth
def: "Depth of the subcutaneous fat on the upper portion of the front leg" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:47:13Z

[Term]
id: ID:0000477
name: side fat
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:47:13Z

[Term]
id: ID:0000478
name: total fatty acid level
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:47:13Z

[Term]
id: ID:0000479
name: muscle lipid level
def: "total lipid content of a muscle" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "total lipid" EXACT []
is_a: MT:0002106 ! muscle physiology
relationship: part_of ID:0000016 ! meat product quality
created_by: caripark
creation_date: 2008-11-11T02:47:13Z

[Term]
id: ID:0000480
name: intramuscular fat weight
def: "weight of the fat present within skeletal muscle, determined through either petroleum-ether or detergent extraction or near-infrared transmission analysis" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
is_a: MT:0001781 ! white fat amount
relationship: part_of ID:0000016 ! meat product quality
created_by: caripark
creation_date: 2008-11-11T02:54:44Z

[Term]
id: ID:0000481
name: intramuscular fat percentage
def: "Mass of fat present within skeletal muscle, determined through either petroleum-ether or detergent extraction or near-infrared transmission analysis, expressed as a percentage of muscle weight" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:54:44Z

[Term]
id: ID:0000482
name: backfat percentage
def: "Weight of subcutaneous fat along the back of the pig, expressed as a percentage of total carcass weight" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:58:47Z

[Term]
id: ID:0000483
name: backfat weight
def: "Weight of subcutaneous fat along the back of the pig" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T02:58:47Z

[Term]
id: ID:0000484
name: backfat (40 kg live weight)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000485
name: backfat (60 kg live weight)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000486
name: average backfat thickness
subset: slim_pig
synonym: "loin fat depth" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000487
name: backfat above muscle dorsi
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000488
name: backfat at first lumbar
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000489
name: backfat at first rib
def: "Subcutaneous fat thickness on the back at the position of the first rib" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000490
name: backfat at last lumbar
def: "Subcutaneous fat thickness on the back at the position of the last lumbar vertebra" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000491
name: backfat at last rib
def: "Subcutaneous fat thickness on the back at the position of the last rib" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000492
name: backfat at neck
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000493
name: backfat at P2 position
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000494
name: backfat at rump
subset: slim_pig
synonym: "rear backfat" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000495
name: backfat at shoulder
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000496
name: backfat at tenth rib
def: "Subcutaneous fat thickness on the back at the position of the tenth rib" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "loin fat depth" RELATED []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000497
name: backfat between 3rd and 4th rib
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000498
name: backfat between 6th and 7th rib
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000499
name: backfat between 3rd and 4th lumbar
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000500
name: backfat at max. mus. depth
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000501
name: backfat on longissimus dorsi at 12th/14th rib
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000502
name: backfat on longissimus dorsi at 13th/14th rib
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000503
name: backfat middle
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000504
name: backfat side
def: "Subcutaneous fat thickness on the animal's side at the interface of the 13th and 14th ribs" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000505
name: backfat 3 vertebrae beneath last rib
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000506
name: backfat at first rib (14 weeks of age)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:18:14Z

[Term]
id: ID:0000507
name: backfat at mid-back
def: "Subcutaneous fat thickness on the back at the mid-point of the body" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000508
name: FOM backfat depth
def: "Loin fat depth measured by Fat-O-Meater" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "Average backfat" RELATED []
synonym: "Loin fat depth" RELATED []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000509
name: loin fat depth
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:14:09Z

[Term]
id: ID:0000510
name: backfat at last rib (14 weeks of age)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:15:39Z

[Term]
id: ID:0000511
name: backfat at last rib (26 weeks of age)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:15:39Z

[Term]
id: ID:0000512
name: backfat at first rib (26 weeks of age)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:18:14Z

[Term]
id: ID:0000513
name: backfat at last lumbar (14 weeks of age)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:19:01Z

[Term]
id: ID:0000514
name: backfat at last lumbar (26 weeks of age)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:19:01Z

[Term]
id: ID:0000515
name: backfat at tenth rib (13 weeks of age)
subset: slim_pig
synonym: "loin fat depth" RELATED []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:20:15Z

[Term]
id: ID:0000516
name: backfat at tenth rib (17 weeks of age)
subset: slim_pig
synonym: "loin fat depth" RELATED []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:20:15Z

[Term]
id: ID:0000517
name: backfat at tenth rib (22 weeks of age)
subset: slim_pig
synonym: "loin fat depth" RELATED []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:20:15Z

[Term]
id: ID:0000518
name: 7-octadecenoic acid level
def: "amount of a monounsaturated fatty acid (C18H34O2), with a carbon-carbon double bond in the n-7 position, present in a sample of fat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "7-octadecenoic acid percentage" EXACT []
is_a: MT:0005285 ! unsaturated fatty acid level
created_by: caripark
creation_date: 2008-11-11T03:26:41Z

[Term]
id: ID:0000519
name: eicosadienoic acid level
def: "amount of an unsaturated fatty acid (C20H36O2), with two carbon-carbon double bonds, present in a sample of fat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "eicosadienoic acid percentage" EXACT []
is_a: MT:0005285 ! unsaturated fatty acid level
created_by: caripark
creation_date: 2008-11-11T03:26:41Z

[Term]
id: ID:0000520
name: eicosenoic acid level
def: "amount of a monounsaturated fatty acid (C20H38O2), with a carbon-carbon double bond in the n-9 position, present in a sample of fat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "eicosenoic acid percentage" EXACT []
is_a: MT:0005285 ! unsaturated fatty acid level
created_by: caripark
creation_date: 2008-11-11T03:26:41Z

[Term]
id: ID:0000521
name: heptadecanoic acid level
def: "amount of a saturated fatty acid (C17H34O2) present in a sample of fat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "fatty acid C17:0" EXACT []
synonym: "heptadecanoic acid percentage" EXACT []
synonym: "margaric acid" EXACT []
is_a: MT:0005286 ! saturated fatty acid level
created_by: caripark
creation_date: 2008-11-11T03:26:41Z

[Term]
id: ID:0000522
name: linoleic acid level
def: "amount of an omega-6 unsaturated fatty acid (C18H32O2), with two carbon-carbon double bonds, present in a sample of fat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "linoleic acid percentage" EXACT []
is_a: MT:0005285 ! unsaturated fatty acid level
created_by: caripark
creation_date: 2008-11-11T03:26:41Z

[Term]
id: ID:0000523
name: linolenic acid level
def: "amount of an omega-3, polyunsaturated fatty acid (C18H30O2), with three carbon-carbon double bonds, present in a sample of fat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "alpha-linolenic acid percentage" EXACT []
synonym: "linolenic acid percentage" EXACT []
is_a: MT:0005285 ! unsaturated fatty acid level
created_by: caripark
creation_date: 2008-11-11T03:26:41Z

[Term]
id: ID:0000524
name: myristic acid level
def: "amount of a saturated fatty acid (C14H28O2), present in a sample of fat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "myristic acid percentage" EXACT []
synonym: "tetradecanoic acid percentage" EXACT []
is_a: MT:0005286 ! saturated fatty acid level
created_by: caripark
creation_date: 2008-11-11T03:26:41Z

[Term]
id: ID:0000525
name: oleic acid level
def: "amount of a monounsaturated, omega-9 fatty acid (C18H34O2), present in a sample of fat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "oleic acid percentage" EXACT []
is_a: MT:0005285 ! unsaturated fatty acid level
created_by: caripark
creation_date: 2008-11-11T03:26:41Z

[Term]
id: ID:0000526
name: palmitic acid level
def: "amount of a saturated fatty acid (C16H32O2) present in a sample of fat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "hexadecanoic acid percentage" EXACT []
synonym: "palmitic acid percentage" EXACT []
is_a: MT:0005286 ! saturated fatty acid level
created_by: caripark
creation_date: 2008-11-11T03:26:41Z

[Term]
id: ID:0000527
name: palmitoleic acid level
def: "amount of an omega-7, monounsaturated fatty acid (C16H30O2) present in a sample of fat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "palmitoleic acid percentage" EXACT []
is_a: MT:0005285 ! unsaturated fatty acid level
created_by: caripark
creation_date: 2008-11-11T03:26:41Z

[Term]
id: ID:0000528
name: stearic acid level
def: "amount of a saturated fatty acid (C18H36O2) present in a sample of fat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "stearic acid percentage" EXACT []
is_a: MT:0005286 ! saturated fatty acid level
created_by: caripark
creation_date: 2008-11-11T03:26:41Z

[Term]
id: ID:0000529
name: androstenone flavor in meat
def: "perceived urine-like flavor in the meat or fat of some uncastrated male pigs" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000102 ! meat flavor
created_by: caripark
creation_date: 2008-11-11T03:29:36Z

[Term]
id: ID:0000530
name: intensity taste
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:29:36Z

[Term]
id: ID:0000531
name: pork flavor in fat
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:29:36Z

[Term]
id: ID:0000532
name: pork flavor in lean
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:29:36Z

[Term]
id: ID:0000533
name: skatole flavor in meat
def: "perceived manure-like flavor in the meat or fat of some uncastrated male pigs" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000102 ! meat flavor
created_by: caripark
creation_date: 2008-11-11T03:29:36Z

[Term]
id: ID:0000534
name: subjective abnormal flavor in fat
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:29:36Z

[Term]
id: ID:0000535
name: subjective abnormal flavor in lean
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:29:36Z

[Term]
id: ID:0000536
name: boar flavor in fat
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:29:36Z

[Term]
id: ID:0000537
name: boar flavor in lean
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:29:36Z

[Term]
id: ID:0000538
name: subjective chew score
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:29:36Z

[Term]
id: ID:0000539
name: meat flavor intensity
def: "scoring scale ranging from no flavor to intense flavor" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "flavor score" EXACT []
synonym: "taste intensity" EXACT []
relationship: part_of ID:0000102 ! meat flavor
created_by: caripark
creation_date: 2008-11-11T03:29:36Z

[Term]
id: ID:0000540
name: subjective juiciness score
def: "Evaluation of the amount of liquid released by a piece of meat during chewing" [CP:Cari Park_Iowa State University curator]
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:29:36Z

[Term]
id: ID:0000541
name: off-flavor score
def: "Detection of any flavor that cannot be described as \"normal\".  Examples include sour, bitter, earthy, and metallic." [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "abnormal flavor" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:29:36Z

[Term]
id: ID:0000542
name: pork flavor in fat
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:29:36Z

[Term]
id: ID:0000543
name: pork flavor in lean
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:29:36Z

[Term]
id: ID:0000544
name: subjective tenderness score
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:29:36Z

[Term]
id: ID:0000545
name: meat color - chroma
def: "a measure of meat color intensity or saturation, =(a^2+b^2)^0.5" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "saturation index" EXACT []
relationship: part_of ID:0000104 ! meat color
created_by: caripark
creation_date: 2008-11-11T03:33:19Z

[Term]
id: ID:0000546
name: meat color a
def: "objective measure of meat redness, measured by a colorimeter" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000104 ! meat color
created_by: caripark
creation_date: 2008-11-11T03:33:19Z

[Term]
id: ID:0000547
name: meat color b
def: "objective measure of meat yellowness, measured by a colorimeter" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000104 ! meat color
created_by: caripark
creation_date: 2008-11-11T03:33:19Z

[Term]
id: ID:0000548
name: meat color L
def: "objective meat color variable for lightness/darkness, based on the amount of light reflected off the surface of the meat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000104 ! meat color
created_by: caripark
creation_date: 2008-11-11T03:33:19Z

[Term]
id: ID:0000549
name: meat color score
def: "subjective determination of meat color, on a scale ranging from pale to dark" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000104 ! meat color
created_by: caripark
creation_date: 2008-11-11T03:33:19Z

[Term]
id: ID:0000550
name: hematin pigmentation
def: "hematin pigment content in fresh muscle" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "haematin pigmentation" EXACT []
relationship: part_of ID:0000104 ! meat color
created_by: caripark
creation_date: 2008-11-11T03:33:19Z

[Term]
id: ID:0000551
name: meat color - hue
def: "perceived meat color due to the dominant wavelength reflected=arctan(b/a)" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "hue angle" EXACT []
relationship: part_of ID:0000104 ! meat color
created_by: caripark
creation_date: 2008-11-11T03:33:19Z

[Term]
id: ID:0000552
name: light reflection
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:33:19Z

[Term]
id: ID:0000553
name: meat brightness
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:33:19Z

[Term]
id: ID:0000554
name: bone/lean meat ratio in ham
def: "Weight of ham bone divided by the weight of lean meat in ham" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000555
name: dressing A
def: "Weight of ham meat relative to carcass weight (%)" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000556
name: dressing B
def: "Weight of bone-in ham relative to carcass weight (%)" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000557
name: carcass fat-free weight
def: "weight of a carcass following slaughter and removal of the head, hide, intestinal tract, and internal organs, and subtracting the weight of fat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: ID:0000114 ! carcass weight
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000558
name: foreloin weight post-dissection
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000559
name: foreloin weight pre-dissection
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000560
name: ham external fat weight
def: "weight of fat trimmed from the surface of the ham" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
xref: CP:Cari Park_Iowa State University curator
relationship: part_of ID:0000563 ! ham weight
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000561
name: ham muscle weight
def: "weight of ham with bone, skin, and fat removed" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "ham meat weight" EXACT []
is_a: ID:0000712 ! skeletal muscle weight
relationship: part_of ID:0000563 ! ham weight
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000562
name: ham percent
def: "Weight of the untrimmed ham expressed as a percentage of carcass weight" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000563
name: ham weight
def: "weight of the untrimmed cut of meat from the hind leg of the pig" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: ID:0000714 ! product weight
relationship: part_of ID:0000689 ! hindlimb weight
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000564
name: lean cuts
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000565
name: lean mass (weight)
def: "Total weight of the trimmed wholesale meat cuts" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "lean meat weight" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000566
name: lean meat + bone in back
def: "Weight of meat and bone in the loin (fat removed), expressed as a proportion of carcass weight" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000567
name: lean meat + bone in ham + back
def: "Total weight of meat and bone in loin and ham, expressed as a proportion of carcass weight" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000568
name: lean percentage
def: "An estimation of the percentage of lean meat in a carcass, based on various muscle and fat measurements" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000569
name: lean thickness between 3rd and 4th rib
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000570
name: loin and belly cut
def: "Weight of the major wholesale cuts of loin and belly, expressed as a percentage of carcass weight" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "loin and belly percentage" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000571
name: loin and ham percentage
def: "Weight of the loin and ham, expressed as a percentage of carcass weight" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000572
name: loin and neck meat weight
def: "Weight of the loin and neck following the removal of external fat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000573
name: loin eye area
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000574
name: longissimus muscle area
def: "cross-sectional area of the loin muscle (longissimus dorsi)" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
synonym: "loin eye area" EXACT []
synonym: "loin muscle area" EXACT []
synonym: "rib eye area" EXACT []
is_a: ID:0000706 ! longissimus dorsi morphology
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000575
name: longissimus muscle depth
def: "the depth/diameter of the longissimus dorsi at a given point" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "eye muscle depth" EXACT []
synonym: "loin height" EXACT []
synonym: "loin muscle depth" EXACT []
is_a: ID:0000706 ! longissimus dorsi morphology
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000576
name: loin percent
def: "Weight of the loin expressed as a percentage of carcass weight" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000577
name: egg weight
def: "weight of a whole, intact egg" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000015 ! egg product quality
created_by: caripark
creation_date: 2008-12-17T08:24:20Z

[Term]
id: ID:0000578
name: longissimus dorsi length
def: "length of the longissimus dorsi muscle" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "loin length" EXACT []
synonym: "longissimus muscle length" EXACT []
is_a: ID:0000706 ! longissimus dorsi morphology
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000579
name: meat area on longissimus dorsi at 13th/14th rib
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000580
name: muscle + diaphragm weight
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000581
name: muscle weight
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000582
name: shoulder muscle weight
def: "Weight of the cut of meat from the upper portion of the front leg of the pig, trimmed of fat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "shoulder meat weight" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T03:57:04Z

[Term]
id: ID:0000583
name: loin muscle area at 4th-5th rib
def: "Cross-sectional area of the loin muscle (longissimus dorsi) between the 4th and 5th rib" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:01:52Z

[Term]
id: ID:0000584
name: loin muscle area at the middle
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:01:52Z

[Term]
id: ID:0000585
name: FOM loin depth
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:02:23Z

[Term]
id: ID:0000586
name: loin depth at the last ribs
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:02:23Z

[Term]
id: ID:0000587
name: smell intensity (meat)
def: "a subjective score describing the perceived odor intensity of cooked meat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000106 ! meat odor
created_by: caripark
creation_date: 2008-11-11T04:05:30Z

[Term]
id: ID:0000588
name: smell intensity (fat)
def: "a subjective score describing the perceived odor intensity of cooked fat removed from a cut of meat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000106 ! meat odor
created_by: caripark
creation_date: 2008-11-11T04:05:30Z

[Term]
id: ID:0000589
name: sub-acid smell
def: "A subjective score describing the intensity of an acidic or sour odor in cooked meat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:05:30Z

[Term]
id: ID:0000590
name: subjective abnormal odor
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:05:30Z

[Term]
id: ID:0000591
name: meat odor acceptability
subset: slim_pig
synonym: "overall acceptability score" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:05:30Z

[Term]
id: ID:0000592
name: pork odor
subset: slim_pig
relationship: part_of ID:0000106 ! meat odor
created_by: caripark
creation_date: 2008-11-11T04:05:30Z

[Term]
id: ID:0000593
name: pH 24 hr post-mortem (ham)
def: "pH of the semimembranosus muscle 24 hours after slaughter" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:09:18Z

[Term]
id: ID:0000594
name: pH 24 hr post-mortem (loin)
def: "pH of the longissimus dorsi muscle 24 hours after slaughter" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:09:18Z

[Term]
id: ID:0000595
name: pH 45 min post-mortem
def: "Muscle pH 45 minutes post-mortem" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:09:18Z

[Term]
id: ID:0000596
name: pH in biceps femoris muscle
def: "relative acidity or alkalinity in the biceps femoris muscle, as measured by the concentration of hydrogen ion" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000685 ! muscle pH
created_by: caripark
creation_date: 2008-11-11T04:09:18Z

[Term]
id: ID:0000597
name: pH in longissimus dorsi muscle
def: "relative acidity or alkalinity in the longissimus dorsi muscle, as measured by the concentration of hydrogen ion" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000685 ! muscle pH
created_by: caripark
creation_date: 2008-11-11T04:09:18Z

[Term]
id: ID:0000598
name: pH in semispinalis dorsi muscle
def: "relative acidity or alkalinity in the semispinalis dorsi muscle, as measured by the concentration of hydrogen ion" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000685 ! muscle pH
created_by: caripark
creation_date: 2008-11-11T04:09:18Z

[Term]
id: ID:0000599
name: pH in semimembranosus muscle
def: "relative acidity or alkalinity in the semimembranosus muscle, as measured by the concentration of hydrogen ion" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000685 ! muscle pH
created_by: caripark
creation_date: 2008-11-11T04:09:18Z

[Term]
id: ID:0000600
name: rigor mortis
def: "development of muscle rigidity that occurs post-mortem as a result of myosin-actin cross-bridging" [CP:Cari Park_Iowa State University curator, MeSH:C23.550.260.224.617.839]
subset: slim_pig
is_a: MT:0005395 ! other trait
created_by: caripark
creation_date: 2008-11-11T04:11:37Z

[Term]
id: ID:0000601
name: average instron (star probe) force
def: "Amount of force (kg) necessary to puncture and/or compress a cut of cooked meat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:15:56Z

[Term]
id: ID:0000602
name: meat chewiness
def: "evaluation of the total number of chews required to sufficiently break up meat before swallowing" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "chew score" EXACT []
synonym: "chewiness score" EXACT []
relationship: part_of ID:0000109 ! meat texture
created_by: caripark
creation_date: 2008-11-11T04:15:56Z

[Term]
id: ID:0000603
name: cooking loss
def: "decrease in the weight of a cut of meat during cooking, mostly due to moisture loss" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000109 ! meat texture
created_by: caripark
creation_date: 2008-11-11T04:15:56Z

[Term]
id: ID:0000604
name: skeletal muscle fiber diameter
def: "average diameter of the multinucleated cells in a cross-section of skeletal muscle" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0003399 ! skeletal muscle fiber size
created_by: caripark
creation_date: 2008-11-11T04:15:56Z

[Term]
id: ID:0000605
name: drip loss
def: "fluid lost from fresh, uncooked meat due to passive exudation" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "purge" EXACT []
synonym: "purge loss" EXACT []
relationship: part_of ID:0000109 ! meat texture
created_by: caripark
creation_date: 2008-11-11T04:15:56Z

[Term]
id: ID:0000606
name: myosin isoform type I content
def: "amount of myosin isoform type I present in a muscle sample, as determined by SDS-PAGE" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "fiber type 1 percentage" RELATED []
relationship: part_of ID:0000746 ! skeletal muscle fiber type
created_by: caripark
creation_date: 2008-11-11T04:15:56Z

[Term]
id: ID:0000607
name: myosin isoform type IIa content
def: "amount of myosin isoform type IIa present in a muscle sample, as determined by SDS-PAGE" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000746 ! skeletal muscle fiber type
created_by: caripark
creation_date: 2008-11-11T04:15:56Z

[Term]
id: ID:0000608
name: meat firmness
def: "subjective evaluation of loin firmness following chilling of carcass" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000109 ! meat texture
created_by: caripark
creation_date: 2008-11-11T04:15:56Z

[Term]
id: ID:0000609
name: meat juiciness
def: "evaluation of the amount of liquid released by a piece of meat during chewing" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "juiciness score" EXACT []
relationship: part_of ID:0000109 ! meat texture
created_by: caripark
creation_date: 2008-11-11T04:15:56Z

[Term]
id: ID:0000610
name: lactate/diameter of white fibers
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:15:56Z

[Term]
id: ID:0000611
name: moisture content
def: "amount of moisture in a cut of meat, determined by the difference in weight before and after oven drying" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000109 ! meat texture
created_by: caripark
creation_date: 2008-11-11T04:15:56Z

[Term]
id: ID:0000612
name: number of type IIb myofibers
def: "average number of type IIb, fast glycolytic fibers in a cross-section of muscle" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "number of white myofibers" EXACT []
relationship: part_of ID:0000746 ! skeletal muscle fiber type
created_by: caripark
creation_date: 2008-11-11T04:15:56Z

[Term]
id: ID:0000613
name: percent cooking loss
def: "Decrease in the weight of a cut of meat during cooking, mostly due to moisture loss (%)." [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:15:56Z

[Term]
id: ID:0000614
name: percentage of white fibers
def: "Number of white (fast-twitch) fibers/total number of fibers in a cross-section of muscle" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:15:56Z

[Term]
id: ID:0000615
name: adenosine deamination
def: "degree of deamination of adenosine in muscle" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "R-value" EXACT []
is_a: MT:0002106 ! muscle physiology
created_by: caripark
creation_date: 2008-11-11T04:15:56Z

[Term]
id: ID:0000616
name: R-value/diameter of white fibers
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:15:56Z

[Term]
id: ID:0000617
name: conformation of feet and legs
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-12-19T12:57:50Z

[Term]
id: ID:0000618
name: meat tenderness
def: "the ease with which meat is broken down during mastication" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
synonym: "tenderness score" EXACT []
relationship: part_of ID:0000109 ! meat texture
created_by: caripark
creation_date: 2008-11-11T04:15:56Z

[Term]
id: ID:0000619
name: water holding capacity
def: "the ability of meat to retain water during cutting, heating, grinding, and pressing." [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000109 ! meat texture
created_by: caripark
creation_date: 2008-11-11T04:15:56Z

[Term]
id: ID:0000620
name: feed conversion ratio
def: "Ratio of amount of feed consumed to body weight gain" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:18:56Z

[Term]
id: ID:0000621
name: feed conversion ratio (35-55 kg)
def: "Ratio of amount of feed consumed to body weight gain between 35 and 55 kg body weight" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:18:56Z

[Term]
id: ID:0000622
name: feed conversion ratio (55-80 kg)
def: "Ratio of amount of feed consumed to body weight gain between 55 and 80 kg body weight" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:18:56Z

[Term]
id: ID:0000623
name: average daily feed intake
def: "Average amount of feed consumed per day" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:20:49Z

[Term]
id: ID:0000624
name: feed intake (35-55 kg)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:20:49Z

[Term]
id: ID:0000625
name: feed intake (55-80 kg)
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:20:49Z

[Term]
id: ID:0000626
name: food consumption
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:20:49Z

[Term]
id: ID:0000627
name: thyroid-stimulating hormone
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:21:43Z

[Term]
id: ID:0000628
name: embryo mortality
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:27:06Z

[Term]
id: ID:0000629
name: fully formed pigs
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:27:06Z

[Term]
id: ID:0000630
name: litter weaning weight
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:27:06Z

[Term]
id: ID:0000631
name: mummified pigs
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:27:06Z

[Term]
id: ID:0000632
name: percentage stillborn
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:27:06Z

[Term]
id: ID:0000633
name: proportion of stillborn
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:27:06Z

[Term]
id: ID:0000634
name: total number born
synonym: "litter size" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:27:06Z

[Term]
id: ID:0000635
name: total number born alive
synonym: "prenatal survival" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:27:06Z

[Term]
id: ID:0000636
name: number of corpora lutea
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:29:40Z

[Term]
id: ID:0000637
name: functional nipples
def: "number of nipples capable of secreting milk in response to suckling by offspring" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0001881 ! mammary gland physiology
created_by: caripark
creation_date: 2008-11-11T04:29:40Z

[Term]
id: ID:0000638
name: uterine capacity
def: "number of viable fetuses a female is capable of supporting to term" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0002637 ! uterus size
created_by: caripark
creation_date: 2008-11-11T04:29:40Z

[Term]
id: ID:0000639
name: uterine horn length
def: "length of the upper right or left portion of the uterus to which the uterine tube is connected" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0002637 ! uterus size
created_by: caripark
creation_date: 2008-11-11T04:29:40Z

[Term]
id: ID:0000640
name: uterine horn weight
def: "weight of the upper right or left portion of the uterus to which the uterine tube is connected" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0002637 ! uterus size
created_by: caripark
creation_date: 2008-11-11T04:29:40Z

[Term]
id: ID:0000641
name: ovary weight
def: "weight of the female reproductive gland containing the germ cells" [CP:Cari Park_Iowa State University curator, ISBN:0-683-40008-8 Stedman's Medical Dictionary\, 27th edition]
subset: slim_pig
relationship: part_of MT:0001127 ! ovary size
created_by: caripark
creation_date: 2008-11-11T04:29:40Z

[Term]
id: ID:0000642
name: uterus length
def: "length of the uterus from the top of the uterine body to the cervix" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "uterine length" EXACT []
relationship: part_of MT:0002637 ! uterus size
created_by: caripark
creation_date: 2008-11-11T04:29:40Z

[Term]
id: ID:0000643
name: daily sperm production
def: "average number of sperm produced per day" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0001156 ! spermatogenesis
created_by: caripark
creation_date: 2008-11-11T04:30:44Z

[Term]
id: ID:0000644
name: testes weight
def: "weight of the male reproductive glands" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0001148 ! testes size
created_by: caripark
creation_date: 2008-11-11T04:30:44Z

[Term]
id: ID:0000645
name: adjusted birthing rate
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:35:38Z

[Term]
id: ID:0000646
name: age at delivery
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:35:38Z

[Term]
id: ID:0000647
name: age at breeding
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:35:38Z

[Term]
id: ID:0000648
name: average breeding female inventory
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:35:38Z

[Term]
id: ID:0000649
name: birth interval
def: "time interval between birth of consecutive offspring" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_pig
relationship: part_of MT:0002907 ! parturition
created_by: caripark
creation_date: 2008-11-11T04:35:38Z

[Term]
id: ID:0000650
name: birth duration
def: "duration of delivery" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0002907 ! parturition
created_by: caripark
creation_date: 2008-11-11T04:35:38Z

[Term]
id: ID:0000651
name: gestation length
subset: slim_cattle
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:35:38Z

[Term]
id: ID:0000652
name: heterogeneity of birth intervals
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:35:38Z

[Term]
id: ID:0000653
name: lactation length
def: "period of time over which milk is produced from the mammary gland" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0001882 ! lactation
created_by: caripark
creation_date: 2008-11-11T04:35:38Z

[Term]
id: ID:0000654
name: log transformation of percentage stillborn
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:35:38Z

[Term]
id: ID:0000655
name: placental efficiency
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:35:38Z

[Term]
id: ID:0000656
name: prenatal survival
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:35:38Z

[Term]
id: ID:0000657
name: vigor score
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:35:38Z

[Term]
id: ID:0000658
name: weight of laparoscopy
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2008-11-11T04:35:38Z

[Term]
id: ID:0000659
name: ACTH level variations
def: "Difference between post-stress and basal levels of pituitary adrenocorticotropic hormone in the blood" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2009-01-09T10:26:05Z

[Term]
id: ID:0000660
name: cortisol level variations
def: "Difference between post-stress and basal levels of cortisol in the blood" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2009-01-09T10:27:17Z

[Term]
id: ID:0000661
name: lymphocyte proliferation
namespace: Trait.ontology
subset: slim_pig
is_a: MT:0000717 ! lymphocyte number
created_by: caripark
creation_date: 2009-02-23T11:12:21Z

[Term]
id: ID:0000662
name: residual feed intake
def: "difference between actual feed intake and the expected feed requirements for maintenance of body weight and for weight gain" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_a: MT:0005449 ! food intake
created_by: caripark
creation_date: 2009-03-06T02:22:41Z

[Term]
id: ID:0000663
name: susceptibility to M. paratuberculosis infection
namespace: Trait.ontology
def: "Likelihood that an organism will be infected with Mycobacterium avium subspecies paratuberculosis, the bacterium that causes Johne's disease in ruminants" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_obsolete: true
created_by: caripark
creation_date: 2009-03-06T02:30:59Z

[Term]
id: ID:0000664
name: feather morphology
namespace: Trait.ontology
subset: slim_chkn
is_a: MT:0005393 ! skin/coat/nails/feathers trait
created_by: caripark
creation_date: 2009-03-10T01:08:34Z

[Term]
id: ID:0000665
name: bacteria count
def: "number of viable bacteria present (cfu)" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
subset: slim_pig
is_a: ID:0000673 ! response to bacterial infection
created_by: caripark
creation_date: 2009-03-13T11:09:51Z

[Term]
id: ID:0000666
name: femur width
def: "width of the femur halfway between the ends" [CP:Cari Park_Iowa State University curator]
is_a: ID:0000369 ! femur dimensions
created_by: caripark
creation_date: 2009-03-25T09:14:54Z

[Term]
id: ID:0000667
name: gizzard morphology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the secondary, muscular stomach in some animals used for grinding up food" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: MT:0000462 ! digestive system morphology
created_by: caripark
creation_date: 2009-03-30T10:31:57Z

[Term]
id: ID:0000668
name: bursa of Fabricius size
def: "size of an epithelial outgrowth of the cloaca in birds where B-lymphocyte maturation occurs" [CP:Cari Park_Iowa State University curator, MeSH:A10.549.175]
subset: slim_chkn
is_a: MT:0002221 ! lymph organ size
created_by: caripark
creation_date: 2009-03-30T12:56:46Z

[Term]
id: ID:0000669
name: induced circulating adrenocorticotropin level
namespace: Trait.ontology
def: "Level of pituitary adrenocorticotropic hormone in the blood in response to an external intervention" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0002664 ! circulating adrenocorticotropin level
created_by: caripark
creation_date: 2009-03-30T01:49:48Z

[Term]
id: ID:0000670
name: circulating cortisol level
def: "blood concentration of a steroid hormone secreted by the adrenal cortex which acts as an anti-inflammatory agent" [CP:Cari Park_Iowa State University curator, ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition"]
subset: slim_pig
synonym: "circulating hydrocortisone level" EXACT []
is_a: ID:0000672 ! cortisol level
is_a: MT:0003366 ! circulating glucocorticoid level
created_by: caripark
creation_date: 2009-03-30T02:24:52Z

[Term]
id: ID:0000671
name: glucocorticoid level
def: "concentration of the corticosteroids regulating carbohydrate metabolism and exhibiting anti-inflammatory activity" [CP:Cari Park_Iowa State University curator, ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition"]
subset: slim_chkn
subset: slim_pig
is_a: MT:0003953 ! hormone level
created_by: caripark
creation_date: 2009-03-30T02:30:33Z

[Term]
id: ID:0000672
name: cortisol level
def: "concentration of a steroid hormone secreted by the adrenal cortex which acts as an anti-inflammatory agent" [CP:Cari Park_Iowa State University curator, ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition"]
subset: slim_pig
synonym: "hydrocortisone level" EXACT []
is_a: ID:0000671 ! glucocorticoid level
created_by: caripark
creation_date: 2009-03-30T02:32:44Z

[Term]
id: ID:0000673
name: response to bacterial infection
def: "the body's reaction to invasion and multiplication of bacteria in its tissues, or the body's reaction to components of or toxins produced by bacteria" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
subset: slim_pig
is_a: MT:0005025 ! response to infection
created_by: caripark
creation_date: 2009-03-30T03:33:42Z

[Term]
id: ID:0000674
name: response to fungal infection
def: "the body's reaction to invasion and multiplication of yeast or mold in its tissues, or the body's reaction to components of or toxins produced by these organisms" [CP:Cari Park_Iowa State University curator]
is_a: MT:0005025 ! response to infection
created_by: caripark
creation_date: 2009-03-30T03:33:42Z

[Term]
id: ID:0000675
name: response to parasitic infection
def: "the body's reaction to invasion and multiplication of parasites in its tissues, or the body's reaction to components of or toxins produced by parasites" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0005025 ! response to infection
created_by: caripark
creation_date: 2009-03-30T03:33:42Z

[Term]
id: ID:0000676
name: response to prion infection
def: "the body's reaction to invasion of small, infectious proteinaceous particles of non-nucleic acid composition in its tissues" [CP:Cari Park_Iowa State University curator, ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition"]
is_a: MT:0005025 ! response to infection
created_by: caripark
creation_date: 2009-03-30T03:33:42Z

[Term]
id: ID:0000677
name: response to viral infection
def: "the body's reaction to invasion and multiplication of a virus in its tissues, or the body's reaction to components of or toxins produced by a virus" [CP:Cari Park_Iowa State University curator]
is_a: MT:0005025 ! response to infection
created_by: caripark
creation_date: 2009-03-30T03:33:42Z

[Term]
id: ID:0000678
name: parasite load
namespace: Trait.ontology
is_obsolete: true
created_by: caripark
creation_date: 2009-03-30T04:00:58Z

[Term]
id: ID:0000679
name: interleukin-2 physiology
def: "characteristic related to the function of this cytokine released by helper T cells that stimulates proliferation of T lymphocytes and activated B lymphocytes" [CP:Cari Park_Iowa State University curator, ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition"]
subset: slim_pig
is_a: MT:0002529 ! interleukin physiology
created_by: caripark
creation_date: 2009-03-31T03:12:32Z

[Term]
id: ID:0000680
name: weight loss in response to infection
def: "loss of weight as a result of the invasion and multiplication of microorganisms, or due to the body's reaction to components of or toxins produced by pathogenic microorganisms" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_a: MT:0001263 ! weight loss
is_a: MT:0005025 ! response to infection
created_by: caripark
creation_date: 2009-03-31T03:39:50Z

[Term]
id: ID:0000681
name: interleukin-2 activity
def: "activity of this cytokine released by helper T cells that stimulates proliferation of T lymphocytes and activated B lymphocytes" [CP:Cari Park_Iowa State University curator, ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition"]
subset: slim_pig
is_a: ID:0000679 ! interleukin-2 physiology
created_by: caripark
creation_date: 2009-03-31T03:52:30Z

[Term]
id: ID:0000682
name: induced interleukin-2 activity
def: "activity of interleukin-2 in response to an external intervention" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: ID:0000681 ! interleukin-2 activity
created_by: caripark
creation_date: 2009-03-31T03:52:54Z

[Term]
id: ID:0000683
name: total heart ventricle size
def: "the physical dimensions, proportions, magnitude, or extent of the lower chambers of the heart" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000059 ! total heart ventricle morphology
created_by: caripark
creation_date: 2009-04-01T03:44:26Z

[Term]
id: ID:0000684
name: total heart ventricle weight
def: "weight of the lower chambers of the heart" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000683 ! total heart ventricle size
created_by: caripark
creation_date: 2009-04-01T03:45:39Z

[Term]
id: ID:0000685
name: muscle pH
def: "relative acidity or alkalinity in the muscle, as measured by the concentration of hydrogen ion" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0002106 ! muscle physiology
is_a: MT:0004043 ! pH regulation
created_by: caripark
creation_date: 2009-04-01T03:49:05Z

[Term]
id: ID:0000686
name: paw/hand/foot/hoof weight
def: "weight of the pedal or prehensile extremity of vertebrates" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0004271 ! paw/hand/foot/hoof morphology
created_by: caripark
creation_date: 2009-04-01T04:28:54Z

[Term]
id: ID:0000687
name: forelimb weight
def: "weight of the anterior extremeties" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
subset: slim_pig
relationship: part_of MT:0000550 ! forelimb morphology
created_by: caripark
creation_date: 2009-04-02T08:23:43Z

[Term]
id: ID:0000688
name: metatarsal bone weight
namespace: Trait.ontology
subset: slim_chkn
synonym: "shank weight" NARROW []
relationship: part_of MT:0003072 ! metatarsal bone morphology
created_by: caripark
creation_date: 2009-04-02T11:09:39Z

[Term]
id: ID:0000689
name: hindlimb weight
def: "weight of the posterior extremeties" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
subset: slim_pig
relationship: part_of MT:0000556 ! hindlimb morphology
created_by: caripark
creation_date: 2009-04-02T11:41:35Z

[Term]
id: ID:0000690
name: flavor in meat
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2009-04-02T02:28:53Z

[Term]
id: ID:0000691
name: flavor in fat
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2009-04-02T02:29:20Z

[Term]
id: ID:0000692
name: humoral immune response rate
namespace: Trait.ontology
synonym: "antibody response rate" EXACT []
is_obsolete: true
created_by: caripark
creation_date: 2009-04-02T03:42:24Z

[Term]
id: ID:0000693
name: unsaturated fatty acid content
subset: slim_pig
is_obsolete: true
created_by: caripark
creation_date: 2009-04-02T04:12:49Z

[Term]
id: ID:0000694
name: muscle glycogen homeostasis
def: "state of equilibrium in the body with respect to this readily converted carbohydrate reserve, found in most tissues, especially liver and muscle" [CP:Cari Park_Iowa State University curator, ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition"]
subset: slim_pig
is_a: MT:0002106 ! muscle physiology
created_by: caripark
creation_date: 2009-04-03T09:59:55Z

[Term]
id: ID:0000695
name: egg albumen morphology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the albumen (white) of an egg" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000015 ! egg product quality
created_by: caripark
creation_date: 2009-04-03T11:33:39Z

[Term]
id: ID:0000696
name: egg shell morphology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the shell of an egg" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000015 ! egg product quality
created_by: caripark
creation_date: 2009-04-03T11:33:39Z

[Term]
id: ID:0000697
name: egg yolk morphology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the yolk of an egg" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000015 ! egg product quality
created_by: caripark
creation_date: 2009-04-03T11:33:39Z

[Term]
id: ID:0000698
name: egg shell physiology
def: "any measurable characterisic related to the function of the shell of an egg" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000015 ! egg product quality
created_by: caripark
creation_date: 2009-04-03T11:35:44Z

[Term]
id: ID:0000699
name: egg yolk diameter
def: "diameter of the yolk when an egg is broken onto a flat surface" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000697 ! egg yolk morphology
created_by: caripark
creation_date: 2009-04-03T11:37:29Z

[Term]
id: ID:0000700
name: egg yolk height
def: "height at the highest point of the yolk when an egg is broken onto a flat surface" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
relationship: part_of ID:0000697 ! egg yolk morphology
created_by: caripark
creation_date: 2009-04-03T11:37:29Z

[Term]
id: ID:0000701
name: product trait
def: "any measurable or observable characteristic of a product produced by or obtained from the body of an animal" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0000001 ! Trait
created_by: caripark
creation_date: 2009-04-06T02:14:59Z

[Term]
id: ID:0000702
name: udder cleft
def: "upward extension and depth of the suspensory ligament separating the two halves of the udder" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
relationship: part_of ID:0000067 ! udder morphology
created_by: caripark
creation_date: 2009-04-23T08:43:06Z

[Term]
id: ID:0000703
name: udder depth
def: "distance between udder floor and tarsal joint (point of the hock), viewed from the side" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
relationship: part_of ID:0000067 ! udder morphology
created_by: caripark
creation_date: 2009-04-23T08:43:06Z

[Term]
id: ID:0000704
name: rear udder height
def: "distance from the udder floor to the point at the top where it joins the body wall" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
relationship: part_of ID:0000067 ! udder morphology
created_by: caripark
creation_date: 2009-04-23T08:43:06Z

[Term]
id: ID:0000705
name: rear udder width
def: "width of the udder at the top of the rear udder attachment" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
relationship: part_of ID:0000067 ! udder morphology
created_by: caripark
creation_date: 2009-04-23T08:43:06Z

[Term]
id: ID:0000706
name: longissimus dorsi morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the muscle of the back which is the intermediate and largest of the continuations of the Sacrospinalis" [ISBN:1587341026 "Gray's Anatomy"]
subset: slim_cattle
subset: slim_pig
is_a: MT:0004248 ! epaxial muscle morphology
created_by: caripark
creation_date: 2009-04-23T01:15:57Z

[Term]
id: ID:0000707
name: skeletal muscle lean weight
def: "actual or estimated weight of skeletal muscle, minus the associated fat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "estimated carcass lean content" NARROW []
synonym: "lean mass" NARROW []
synonym: "lean meat weight" NARROW []
synonym: "lean muscle mass" EXACT []
is_a: ID:0000712 ! skeletal muscle weight
created_by: caripark
creation_date: 2009-04-27T02:57:55Z

[Term]
id: ID:0000708
name: reflectance value
def: "a measurement of light reflection from the surface of meat, used to measure color or quantitate myoglobin forms" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "light reflection" EXACT []
relationship: part_of ID:0000104 ! meat color
created_by: caripark
creation_date: 2009-04-28T10:04:07Z

[Term]
id: ID:0000709
name: shoulder muscle weight
def: "weight of the cut of meat from the upper portion of the front leg of the pig, trimmed of fat" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: ID:0000712 ! skeletal muscle weight
relationship: part_of ID:0000422 ! shoulder weight
created_by: caripark
creation_date: 2009-04-28T01:47:10Z

[Term]
id: ID:0000710
name: pectoralis muscle morphology
subset: slim_chkn
is_obsolete: true
created_by: caripark
creation_date: 2009-04-28T01:59:13Z

[Term]
id: ID:0000711
name: abdominal fat pad weight
def: "weight of the encapsulated adipose tissue in the abdomen" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: MT:0000010 ! abdominal fat pad morphology
created_by: caripark
creation_date: 2009-04-29T03:54:23Z

[Term]
id: ID:0000712
name: skeletal muscle weight
def: "weight of one or more of the striated muscles attached to the skeleton" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0003398 ! skeletal muscle size
is_a: MT:0004233 ! muscle weight
created_by: caripark
creation_date: 2009-05-01T04:13:32Z

[Term]
id: ID:0000713
name: myosin isoform type IIb content
def: "amount of myosin isoform type IIb present in a muscle sample, as determined by SDS-PAGE" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000746 ! skeletal muscle fiber type
created_by: caripark
creation_date: 2009-05-01T05:21:37Z

[Term]
id: ID:0000714
name: product weight
def: "weight of a product produced by or obtained from the body of an animal" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: ID:0000701 ! product trait
created_by: caripark
creation_date: 2009-05-04T03:19:20Z

[Term]
id: ID:0000715
name: egg morphology
is_obsolete: true
created_by: caripark
creation_date: 2009-05-04T03:53:47Z

[Term]
id: ID:0000716
name: egg physiology
is_obsolete: true
created_by: caripark
creation_date: 2009-05-04T03:53:47Z

[Term]
id: ID:0000717
name: response to novel food
def: "reaction upon exposure to novel food" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: MT:0001431 ! eating behavior
is_a: MT:0003107 ! response to novelty
created_by: caripark
creation_date: 2009-05-05T03:47:58Z

[Term]
id: ID:0000718
name: pH in semispinalis capitis muscle
def: "relative acidity or alkalinity in the semispinalis capitis muscle, as measured by the concentration of hydrogen ion" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000685 ! muscle pH
created_by: caripark
creation_date: 2009-05-05T03:53:48Z

[Term]
id: ID:0000719
name: ham bone weight
def: "weight of bone in the ham" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000563 ! ham weight
created_by: caripark
creation_date: 2009-05-06T09:06:13Z

[Term]
id: ID:0000720
name: nonfunctional nipples
def: "number of nipples incapable of secreting milk in response to suckling by offspring" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0001881 ! mammary gland physiology
created_by: caripark
creation_date: 2009-05-06T09:39:43Z

[Term]
id: ID:0000721
name: band neutrophil count
def: "number of immature neutrophils undergoing granulopoiesis; nuclei are unsegmented" [CP:Cari Park_Iowa State University curator, ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition"]
subset: slim_pig
synonym: "band-formed neutrophil count" EXACT []
is_a: MT:0000222 ! neutrophil count
created_by: caripark
creation_date: 2009-05-06T10:28:10Z

[Term]
id: ID:0000722
name: milk energy yield
def: "the energy content of milk; may be based on a combination of fat, protein, lactose, ash, and water content" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
relationship: part_of ID:0000019 ! milk product quality
created_by: caripark
creation_date: 2009-05-06T11:33:11Z

[Term]
id: ID:0000723
name: testes volume
def: "volume of the male reproductive glands" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
relationship: part_of MT:0001148 ! testes size
created_by: caripark
creation_date: 2009-05-06T11:41:01Z

[Term]
id: ID:0000724
name: phytohemagglutin (PHA)-induced lymphocyte proliferation
def: "proliferation of lymphocytes upon stimulation with phytohemagglutinin, a mucoprotein isolated from the kidney bean" [CP:Cari Park_Iowa State University curator, MeSH:D12.776.765.678.750]
subset: slim_pig
is_a: ID:0000393 ! mitogen-induced lymphocyte proliferation
created_by: caripark
creation_date: 2009-05-06T01:13:37Z

[Term]
id: ID:0000725
name: milking speed
def: "subjective assessment of the time required for milking in relation to the milk yield" [CP:Cari Park_Iowa State University curator]
is_a: MT:0001882 ! lactation
created_by: caripark
creation_date: 2009-05-06T03:11:07Z

[Term]
id: ID:0000726
name: angularity
def: "conformation of the animal's back, withers, and neck, viewed from behind" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
synonym: "dairy form" EXACT []
is_a: ID:0000000 ! conformation
created_by: caripark
creation_date: 2009-05-06T03:13:00Z

[Term]
id: ID:0000727
name: teat placement
def: "alignment of the teats in relation to each other" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_a: MT:0006078 ! nipple morphology
created_by: caripark
creation_date: 2009-05-06T03:19:16Z

[Term]
id: ID:0000728
name: <new term>
is_obsolete: true
created_by: caripark
creation_date: 2009-05-06T03:22:23Z

[Term]
id: ID:0000729
name: carcass temperature
def: "temperature of the carcass at a given time post-mortem" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0005535 ! body temperature
created_by: caripark
creation_date: 2009-05-07T09:43:03Z

[Term]
id: ID:0000730
name: height at withers
def: "height of an animal measured from the ground to the high point on the back, between the shoulder blades" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_a: MT:0001253 ! body height
created_by: caripark
creation_date: 2009-05-07T11:05:57Z

[Term]
id: ID:0000731
name: chest width
def: "width of the chest, viewed from the front" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
synonym: "strength" RELATED []
relationship: part_of MT:0004134 ! chest morphology
created_by: caripark
creation_date: 2009-05-07T12:48:20Z

[Term]
id: ID:0000732
name: chest depth
def: "dorsal-ventral dimension of the chest, measured directly behind the front legs" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
relationship: part_of MT:0004134 ! chest morphology
created_by: caripark
creation_date: 2009-05-07T12:59:41Z

[Term]
id: ID:0000733
name: heel depth
def: "vertical distance from the ground to the hairline at the back of the hoof" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
relationship: part_of MT:0004271 ! paw/hand/foot/hoof morphology
created_by: caripark
creation_date: 2009-05-07T01:17:19Z

[Term]
id: ID:0000734
name: hoof diagonal
def: "distance from the tip of the hoof to the hairline at the back of the hoof" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
synonym: "foot diagonal" EXACT []
relationship: part_of MT:0004271 ! paw/hand/foot/hoof morphology
created_by: caripark
creation_date: 2009-05-07T01:17:19Z

[Term]
id: ID:0000735
name: hoof angle
def: "angle at which the hoof wall meets the ground" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
synonym: "foot angle" EXACT []
relationship: part_of MT:0004271 ! paw/hand/foot/hoof morphology
created_by: caripark
creation_date: 2009-05-07T01:17:19Z

[Term]
id: ID:0000736
name: temperament
def: "general attitude or characteristic reactions of an organism exhibited toward another organism" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_a: MT:0002557 ! social/conspecific interaction
created_by: caripark
creation_date: 2009-05-07T01:31:27Z

[Term]
id: ID:0000737
name: hind leg set
def: "squareness of the hind legs in relation to the body; may be assessed from the side or from behind" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
synonym: "rear leg set" EXACT []
relationship: part_of MT:0000556 ! hindlimb morphology
created_by: caripark
creation_date: 2009-05-07T01:44:48Z

[Term]
id: ID:0000738
name: conformation of feet and legs
def: "assessment of the overall structure and proportions of the feet and legs" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_a: ID:0000000 ! conformation
is_a: MT:0002109 ! limb morphology
created_by: caripark
creation_date: 2009-05-07T01:53:41Z

[Term]
id: ID:0000739
name: rump morphology
def: "any measurable or observable characteristic related to the shape or structure of the hindquarters" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
is_a: MT:0002089 ! postnatal growth/weight/body size
created_by: caripark
creation_date: 2009-05-07T02:23:12Z

[Term]
id: ID:0000740
name: rump width
def: "distance between the caudal protrusions of the pelvis, viewed from behind" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
synonym: "thurl width" EXACT []
relationship: part_of ID:0000739 ! rump morphology
created_by: caripark
creation_date: 2009-05-07T02:27:08Z

[Term]
id: ID:0000741
name: rump angle
def: "slope of the topline of the rump, between the cranial and caudal protrusions of the pelvic bone, viewed from the side" [CP:Cari Park_Iowa State University curator]
subset: slim_cattle
relationship: part_of ID:0000739 ! rump morphology
created_by: caripark
creation_date: 2009-05-07T02:27:08Z

[Term]
id: ID:0000742
name: sarcomere length
def: "length of the segment of a myofibril between two Z lines" [CP:Cari Park_Iowa State University curator, ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition"]
subset: slim_pig
is_a: MT:0004090 ! sarcomere morphology
created_by: caripark
creation_date: 2009-05-07T02:45:53Z

[Term]
id: ID:0000743
name: skeletal muscle fiber number
def: "number of large multinucleated cells in a cross-section of skeletal muscle" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0003084 ! skeletal muscle fiber morphology
created_by: caripark
creation_date: 2009-05-07T03:19:34Z

[Term]
id: ID:0000744
name: neck weight
def: "weight of the cut of meat from the dorsal side of the pig, anterior to the third rib" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: ID:0000714 ! product weight
created_by: caripark
creation_date: 2009-05-07T03:37:37Z

[Term]
id: ID:0000745
name: jowl weight
def: "weight of the cut of meat obtained from the cheek of the pig" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: ID:0000714 ! product weight
created_by: caripark
creation_date: 2009-05-07T03:46:46Z

[Term]
id: ID:0000746
name: skeletal muscle fiber type
def: "classification of skeletal muscle fibers based on myosin isoform content and oxidative/glycolytic capacity" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
is_a: MT:0002106 ! muscle physiology
created_by: caripark
creation_date: 2009-05-07T03:52:39Z

[Term]
id: ID:0000747
name: number of type I myofibers
def: "average number of type I, slow oxidative fibers in a cross-section of muscle" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000746 ! skeletal muscle fiber type
created_by: caripark
creation_date: 2009-05-07T07:22:41Z

[Term]
id: ID:0000748
name: number of type IIa myofibers
def: "average number of type IIa, fast oxidative fibers in a cross-section of muscle" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of ID:0000746 ! skeletal muscle fiber type
created_by: caripark
creation_date: 2009-05-07T07:22:41Z

[Term]
id: ID:0000749
name: area of type I myofibers
namespace: Trait.ontology
def: "total area in a cross-section of skeletal muscle occupied by type I, slow oxidative fibers" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0003399 ! skeletal muscle fiber size
created_by: caripark
creation_date: 2009-05-07T07:31:16Z

[Term]
id: ID:0000750
name: area of type IIa myofibers
namespace: Trait.ontology
def: "total area in a cross-section of skeletal muscle occupied by type IIa, fast oxidative fibers" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0003399 ! skeletal muscle fiber size
created_by: caripark
creation_date: 2009-05-07T07:31:16Z

[Term]
id: ID:0000751
name: area of type IIb myofibers
namespace: Trait.ontology
def: "total area in a cross-section of skeletal muscle occupied by type IIb, fast glycolytic fibers" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
relationship: part_of MT:0003399 ! skeletal muscle fiber size
created_by: caripark
creation_date: 2009-05-07T07:31:16Z

[Term]
id: ID:0000752
name: number of IgM-positive B cells
def: "subpopulation of peripheral blood mononuclear cells that stain positive for immunoglobulin M" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "IgM-positive leukocytes" EXACT []
is_a: MT:0002459 ! B cell physiology
created_by: caripark
creation_date: 2009-05-07T07:45:57Z

[Term]
id: ID:0000753
name: number of CD4+ T cells
def: "subpopulation of peripheral blood mononuclear cells that stain positive for CD4" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "number of CD4-positive leukocytes" EXACT []
is_a: MT:0005463 ! CD4+ T cell physiology
created_by: caripark
creation_date: 2009-05-07T07:50:21Z

[Term]
id: ID:0000754
name: number of CD8+ T cells
def: "subpopulation of peripheral blood mononuclear cells that stain positive for CD8" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "number of CD8-positive leukocytes" EXACT []
is_a: MT:0004392 ! CD8+ T cell physiology
created_by: caripark
creation_date: 2009-05-07T07:51:21Z

[Term]
id: ID:0000755
name: number of N1c-positive T cells
def: "subpopulation of peripheral blood mononuclear cells expressing gamma and delta chains of the T cell receptor" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "number of N1c-positive leukocytes" EXACT []
is_a: MT:0002444 ! T cell physiology
created_by: caripark
creation_date: 2009-05-07T07:53:29Z

[Term]
id: ID:0000756
name: number of MHCII-positive B cells
def: "subpopulation of peripheral blood mononuclear cells that stain positive for major histocompatibility complex class II" [CP:Cari Park_Iowa State University curator]
subset: slim_pig
synonym: "MHCII-positive leukocytes" EXACT []
is_a: MT:0002459 ! B cell physiology
created_by: caripark
creation_date: 2009-05-07T07:57:05Z

[Term]
id: ID:0000757
name: number of CD2+ lymphocytes
def: "subpopulation of peripheral blood mononuclear cells that stain positive for CD2" [CP:Cari Park_Iowa State University curator]
synonym: "number of CD2-positive leukocytes" EXACT []
synonym: "number of CD2-positive lymphocytes" EXACT []
is_a: MT:0003945 ! lymphocyte physiology
created_by: caripark
creation_date: 2009-05-07T07:59:29Z

[Term]
id: MT:0000001
name: Trait
namespace: Trait.ontology
subset: slim_cattle
subset: slim_chkn
subset: slim_pig

[Term]
id: MT:0000002
name: head size
namespace: Trait.ontology
def: "physical dimensions of the head" [smb:MGI_curator]
subset: slim_pig
is_a: MT:0000432 ! head morphology

[Term]
id: MT:0000003
name: adipose tissue morphology
namespace: Trait.ontology
alt_id: MT:0000011
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "adipose tissue abnormalities" EXACT []
is_a: MT:0005375 ! adipose tissue trait

[Term]
id: MT:0000005
name: right atrium size
namespace: Trait.ontology
def: "the physical dimensions, proportions, magnitude, or extent of the right upper chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "right atrial size" RELATED []
is_a: MT:0003140 ! atrium size
relationship: part_of MT:0000019 ! right atrium morphology

[Term]
id: MT:0000006
name: atrial appendage completeness
namespace: Trait.ontology
def: "any measurable or observable characteristic pertaining to the wholeness of the small trabeculated chamber projecting  from the atrium proper" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0004253 ! atrium appendage integrity

[Term]
id: MT:0000008
name: atrium appendage configuration
namespace: Trait.ontology
def: "any measurable characteristic of the arrangement of the small trabeculated chamber projecting  from the atrium proper" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "atrial appendage configuration" RELATED []
relationship: part_of MT:0000024 ! atrium appendage morphology

[Term]
id: MT:0000009
name: atrium septum completeness
namespace: Trait.ontology
def: "any measurable or observable characteristic pertaining to the wholeness of the wall between the upper chambers of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "atrial septal completeness" RELATED []
relationship: part_of MT:0000282 ! atrium septum integrity

[Term]
id: MT:0000010
name: abdominal fat pad morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the encapsulated adipose tissue in the abdomen" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: MT:0005334 ! fat pad morphology

[Term]
id: MT:0000012
name: left atrium size
namespace: Trait.ontology
def: "the physical dimensions, proportions, magnitude, or extent of the left upper chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "left atrial size" RELATED []
is_a: MT:0003140 ! atrium size
relationship: part_of MT:0000020 ! left atrium morphology

[Term]
id: MT:0000013
name: fat distribution
namespace: Trait.ontology
subset: slim_cattle
subset: slim_pig
is_a: MT:0000003 ! adipose tissue morphology

[Term]
id: MT:0000015
name: outer ear pigmentation
namespace: Trait.ontology
def: "coloration of the outer ear" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002095 ! skin pigmentation
is_a: MT:0002177 ! outer ear morphology

[Term]
id: MT:0000017
name: ear size
namespace: Trait.ontology
def: "length, width, or area of the outer ears " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "outer ear size" RELATED []
is_a: MT:0002177 ! outer ear morphology

[Term]
id: MT:0000018
name: ventricle membranous septum morphology
namespace: Trait.ontology
def: "any measurable or observable structural characteristic of the membranous portion of the wall between the lower chambers of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "interventricular membranous septum thickness" RELATED []
synonym: "ventricular membranous septal thickness" RELATED []
relationship: part_of MT:0007082 ! ventricle septum morphology

[Term]
id: MT:0000019
name: right atrium morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the right upper chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "right atrial morphology" RELATED []
is_a: MT:0003105 ! heart atrium morphology

[Term]
id: MT:0000020
name: left atrium morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the left upper chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "left atrial morphology" RELATED []
is_a: MT:0003105 ! heart atrium morphology

[Term]
id: MT:0000021
name: outer ear prominence
namespace: Trait.ontology
def: "distance from the outer edge of the outer ear to the head" [J:61768]
is_a: MT:0002177 ! outer ear morphology

[Term]
id: MT:0000022
name: ear shape
namespace: Trait.ontology
def: "pattern of the external ear" [J:65038]
is_a: MT:0002177 ! outer ear morphology

[Term]
id: MT:0000023
name: ear distance/ position
namespace: Trait.ontology
def: "distance between or the placement of the outer ears " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002177 ! outer ear morphology

[Term]
id: MT:0000024
name: atrium appendage morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the small trabeculated chamber projecting  from the atrium proper" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "atrial appendage morphology" RELATED []
relationship: part_of MT:0003105 ! heart atrium morphology

[Term]
id: MT:0000025
name: atrioventricular valve morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the valves that gate the flow of blood from the atria into the ventricles" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
is_a: MT:0000285 ! heart valve morphology

[Term]
id: MT:0000026
name: inner ear morphology
namespace: Trait.ontology
def: "malformation or malfunction of any components of the labyrinth, including the semicircular canals, vestibule and cochlea" [J:1776, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
xref: GO:0042472
is_a: MT:0002102 ! ear morphology

[Term]
id: MT:0000027
name: head width
namespace: Trait.ontology
def: "ear to ear distance across the head" [smb:MGI_curator]
is_a: MT:0000002 ! head size

[Term]
id: MT:0000028
name: pars superior vestibularis morphology
namespace: Trait.ontology
def: "form or structure of the part of the vestibular ganglion that receives fibers from the maculae of the utricle and the sacculae and the ampullae of the anterior and lateral semicircular ducts" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000026 ! inner ear morphology
is_a: MT:0002856 ! vestibular ganglion morphology

[Term]
id: MT:0000029
name: malleus morphology
namespace: Trait.ontology
def: "form or structure of the largest of the three auditory ossicles, which resembles a club or hammer " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal malleus" EXACT []
is_a: MT:0005105 ! middle ear ossicle morphology

[Term]
id: MT:0000030
name: tympanic ring morphology
namespace: Trait.ontology
def: "form or structure of the bony ring at the ear canal to which the tympanic membrane is attached" [J:23837, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000049 ! middle ear morphology

[Term]
id: MT:0000031
name: cochlea morphology
namespace: Trait.ontology
def: "form or structure of the spiral-shaped bony canal in the inner ear containing the hair cells that transduce sound" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000026 ! inner ear morphology

[Term]
id: MT:0000032
name: cochlear integrity
namespace: Trait.ontology
def: "susceptibility of the cochlea to degeneration or atrophy" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0000031 ! cochlea morphology

[Term]
id: MT:0000033
name: mitral valve morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the valve between the left atrium and the left ventricle of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
is_a: MT:0000025 ! atrioventricular valve morphology

[Term]
id: MT:0000034
name: vestibule morphology
namespace: Trait.ontology
def: "form or structure of the cavity between the semicircular canals and the cochlea of the inner ear" [J:1776, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000026 ! inner ear morphology

[Term]
id: MT:0000035
name: membranous labyrinth
namespace: Trait.ontology
def: "form or structure of the complex arrangement of communicating canaliculi and sacs suspended within the cavity of the bony labyrinth of the inner ear" [J:23837, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000026 ! inner ear morphology

[Term]
id: MT:0000036
name: tricuspid valve morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the valve between the right atrium and the right ventricle of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
is_a: MT:0000025 ! atrioventricular valve morphology

[Term]
id: MT:0000037
name: lateral semicircular canal
namespace: Trait.ontology
def: "shape or structure of the lateral long bony tube of the labyrinth that is involved in the sense of balance " [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal horizontal semicircular canal" EXACT []
is_a: MT:0002428 ! semicircular canal

[Term]
id: MT:0000038
name: head length
namespace: Trait.ontology
def: "anterior to posterior length of the head" [smb:MGI_curator]
is_a: MT:0000002 ! head size

[Term]
id: MT:0000039
name: otic capsule morphology
namespace: Trait.ontology
def: "form or structure of the cartilage or bony capsule surrounding the inner ear mechanism" [J:23837, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "periotic capsule morphology" EXACT []
is_a: MT:0000026 ! inner ear morphology

[Term]
id: MT:0000040
name: aortic valve morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the valve between the left ventricle and the ascending aorta" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
is_a: MT:0002746 ! semilunar valve morphology

[Term]
id: MT:0000041
name: endolymphatic duct size
namespace: Trait.ontology
def: "length, width, or area of the small membranous canal of the inner ear; connecting membranous labyrinth with the endolymphatic sac" [J:1776, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0006011 ! endolymphatic duct morphology

[Term]
id: MT:0000042
name: organ of Corti
namespace: Trait.ontology
def: "form or structure of the highly specialized epithelium in the floor of the ductus cochlearis; also referred to a spiral organ (organum spirale), or acoustic papilla" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "spiral organ morphology" EXACT []
is_a: MT:0003169 ! scala media morphology

[Term]
id: MT:0000043
name: organ of Corti integrity
namespace: Trait.ontology
def: "susceptibility to impairment of function or destruction of the highly specialized epithelium in the floor of the ductus cochlearis" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "susceptibility to degeneration of organ of Corti" EXACT []
is_a: MT:0000042 ! organ of Corti

[Term]
id: MT:0000044
name: pulmonary valve morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the valve between the right ventricle and the pulmonary trunk" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
is_a: MT:0002746 ! semilunar valve morphology

[Term]
id: MT:0000045
name: hair cell morphology
namespace: Trait.ontology
def: "form, structure, organization or number of the sensory epithelial cells of the inner ear" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal hair cells" EXACT []
is_a: MT:0000026 ! inner ear morphology
is_a: MT:0000972 ! mechanoreceptor morphology

[Term]
id: MT:0000046
name: sulcus ampullaris morphology
namespace: Trait.ontology
def: "form or structure of the transverse groove on the membranous amupulla of each semicircular duct, where the nerve enters the ampullary crest" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "ampullary groove morphology" EXACT []
synonym: "ampullary sulcus morphology" EXACT []
is_a: MT:0000026 ! inner ear morphology

[Term]
id: MT:0000047
name: head circumference
namespace: Trait.ontology
is_a: MT:0000002 ! head size

[Term]
id: MT:0000048
name: stria vascularis morphology
namespace: Trait.ontology
def: "form or structure of the stratified, secretory epithelium which lines the upper part of the cochlear spiral ligament and maintains K+ homeostasis in the endolymph; stria vascularis normally consists of marginal, intermediate, and basal cells: basal and marginal cell tight junctions preclude paracellular diffusion into and out of the intrastrial space while basal and intermediate cells secrete into this space K+ derived from fibrocytes through gap junctions" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "psalterial cord morphology" EXACT []
synonym: "stria vascularis ductus cochlearis morphology" EXACT []
synonym: "vascular stripe morphology" EXACT []
is_a: MT:0003169 ! scala media morphology

[Term]
id: MT:0000049
name: middle ear morphology
namespace: Trait.ontology
def: "form or structure of any components of the tympanic cavity or its ossicles" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002102 ! ear morphology

[Term]
id: MT:0000051
name: testes physiology
namespace: Trait.ontology
is_a: MT:0005647 ! sex gland physiology

[Term]
id: MT:0000052
name: onset of ear unfolding
namespace: Trait.ontology
def: "timing of the initiation of opening and spreading out of the outer ear" [J:39752]
is_a: MT:0002177 ! outer ear morphology

[Term]
id: MT:0000053
name: heart integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the structural completeness or structural soundness of the organ that pumps blood through the body" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "cardiac integrity" RELATED []
relationship: part_of MT:0000266 ! cardiac morphology

[Term]
id: MT:0000054
name: onset of ear emergence
namespace: Trait.ontology
def: "timing of the start of the growth of the outer ear" [J:49421]
synonym: "onset of ear elevation" EXACT []
synonym: "onset of ear extroversion" EXACT []
is_a: MT:0002177 ! outer ear morphology

[Term]
id: MT:0000057
name: osteogenesis
namespace: Trait.ontology
alt_id: MT:0001535
alt_id: MT:0001536
def: "anomalous process of bone formation" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal bone formation" EXACT []
synonym: "abnormal osteogenesis" EXACT []
synonym: "abnormal skeletogenesis" EXACT []
synonym: "osteogenesis abnormalities" EXACT []
synonym: "skeletogenesis abnormalities" EXACT []
is_a: MT:0002113 ! skeleton development

[Term]
id: MT:0000058
name: heart muscle compact layer morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the outer, dense layer of the myocardium" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "myocardial compact layer morphology" RELATED []
relationship: part_of MT:0005329 ! heart muscle morphology

[Term]
id: MT:0000059
name: osteoclast formation
namespace: Trait.ontology
def: "anomalous development of this multinucleated cell, which normally functions in the absorption and removal of osseous tissue" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal osteophage formation" EXACT []
is_a: MT:0000057 ! osteogenesis

[Term]
id: MT:0000060
name: onset of bone ossification
namespace: Trait.ontology
def: "late onset of the formation of bone" [J:40203]
is_a: MT:0000057 ! osteogenesis

[Term]
id: MT:0000061
name: heart muscle fiber morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the multinucleated muscle cells comprising the myocardium" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "myocardial fiber morphology" RELATED []
relationship: part_of MT:0005329 ! heart muscle morphology

[Term]
id: MT:0000062
name: heart muscle trabeculae morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the supporting bundles of muscular fibers lining the walls of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "cardiac muscle trabeculae morphology" RELATED []
synonym: "myocardial trabeculae morphology" RELATED []
relationship: part_of MT:0005329 ! heart muscle morphology

[Term]
id: MT:0000063
name: ventricle papillary muscle morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the group of myocardial bundles which terminate in the chordae tendineae that attach to the cusps of the atrioventricular valves; each ventricle has an anterior and a posterior papillary muscle; the right ventricle sometimes has a septal papillary muscle" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "musculus papillaris morphology" RELATED []
xref: MP:0004058
relationship: part_of MT:0005294 ! heart ventricle morphology
relationship: part_of MT:0005329 ! heart muscle morphology

[Term]
id: MT:0000064
name: secondary bone resorption
namespace: Trait.ontology
def: "inability of osteoclasts to degrade the organic and inorganic phases of bone by absorption" [J:61295, J:67040]
is_a: MT:0001541 ! osteoclast physiology

[Term]
id: MT:0000065
name: bone marrow cavity morphology
namespace: Trait.ontology
def: "absence or abnormal size or shape of the medullary cavities of the bones" [J:61295, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000168 ! bone marrow development

[Term]
id: MT:0000066
name: osteoporosis
namespace: Trait.ontology
def: "reduction in bone mass or atrophy of skeletal tissue; may lead to skeletal fragility" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:57315, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "reduced bone mass" EXACT []
is_a: MT:0004016 ! bone mass

[Term]
id: MT:0000067
name: osteopetrosis
namespace: Trait.ontology
def: "excessive formation of dense trabecular bone and excessive calcified cartilage formation; may lead to anemia and extramedullary hematopoiesis " [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0004016 ! bone mass

[Term]
id: MT:0000069
name: kyphoscoliosis
namespace: Trait.ontology
def: "kyphosis combined with scoliosis" [cml:Cathleen M. Lutz_Mouse Genome Informatics Curator, J:66943]
is_a: MT:0004174 ! spine curvature

[Term]
id: MT:0000071
name: axial skeleton cell number
namespace: Trait.ontology
def: "reduced cell number in the skeletal elements of the trunk" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:55583, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "hypoplastic axial skeleton" EXACT []
is_a: MT:0002114 ! axial skeleton morphology

[Term]
id: MT:0000073
name: heart muscle integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness  of the involuntary muscle comprising the myocardium" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "cardiac muscle integrity" RELATED []
synonym: "myocardial integrity" RELATED []
relationship: part_of MT:0000053 ! heart integrity
relationship: part_of MT:0005329 ! heart muscle morphology

[Term]
id: MT:0000074
name: neurocranium morphology
namespace: Trait.ontology
def: "malformed bones of the skull enclosing the brain" [J:55583, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal neurocranium" EXACT []
is_a: MT:0000438 ! skull morphology

[Term]
id: MT:0000075
name: blood-brain barrier morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the group of barriers and transport systems in the brain capillary endothelium that controls the entrance of substances into the brain extracellular space from the blood" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0001614 ! blood vessel morphology

[Term]
id: MT:0000076
name: calvaria morphology
namespace: Trait.ontology
def: "malformed upper domelike portion of the skull" [J:61509]
synonym: "abnormal calvaria" EXACT []
synonym: "abnormal cranial vault" EXACT []
is_a: MT:0000074 ! neurocranium morphology

[Term]
id: MT:0000077
name: interparietal bone morphology
namespace: Trait.ontology
alt_id: MT:0000110
def: "any structural anomaly of the bone of the cranium that lies above and anterior to the occipital bone in some mammals" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:61509]
synonym: "abnormal interparietal bone" EXACT []
is_a: MT:0000076 ! calvaria morphology

[Term]
id: MT:0000078
name: supraoccipital bone morphology
namespace: Trait.ontology
def: "any structural anomaly of the bone on the dorsal side of the great foramen of the skull, usually forming a part of the occipital in the adult, but distinct in the young" [J:61509]
synonym: "abnormal supraoccipital bone" EXACT []
is_a: MT:0005269 ! occipital bone morphology

[Term]
id: MT:0000079
name: basioccipital bone morphology
namespace: Trait.ontology
def: "any structural anomaly of the basilar process of the occipital bone in the base of the cranium, frequently forming a direct part of the occipital in the adult, but usually distinct in the young " [J:55583, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal basioccipital bone" EXACT []
is_a: MT:0005269 ! occipital bone morphology

[Term]
id: MT:0000080
name: exoccipital bone morphology
namespace: Trait.ontology
def: "any structural anomaly of the bone or region on the lateral sides of the great foremen of the skull, which often forms a part of the occipital in the adult, but is usually distinct in the young" [J:23837, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal exoccipital bone" EXACT []
is_a: MT:0005269 ! occipital bone morphology

[Term]
id: MT:0000081
name: onset of suture closure
namespace: Trait.ontology
alt_id: MT:0005268
def: "early fusion of the bones of the skull" [J:26513]
synonym: "craniostosis" EXACT []
synonym: "craniosynostosis" EXACT []
is_a: MT:0003420 ! onset of intramembranous bone ossification

[Term]
id: MT:0000082
name: overlapping parietal bones
namespace: Trait.ontology
def: "parietal bones of the skull partly coincide instead of articulating" [J:26513]
is_a: MT:0000109 ! parietal bone morphology

[Term]
id: MT:0000083
name: ectopic cranial bone growth
namespace: Trait.ontology
def: "growth of extra bony structures in or near the cranium" [J:26513]
synonym: "heterotopic cranial bone growth" EXACT []
is_a: MT:0000076 ! calvaria morphology

[Term]
id: MT:0000084
name: fontanelle morphology
namespace: Trait.ontology
def: "structural defect in the membranous interval at the margins of cranial bones in neonates" [J:53370, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal fontanel" EXACT []
synonym: "abnormal fontanelle" EXACT []
is_a: MT:0000076 ! calvaria morphology
is_a: MT:0002113 ! skeleton development

[Term]
id: MT:0000085
name: blood-cerebrospinal fluid barrier morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the group of barriers and transport systems in the choroid plexus located in the lateral, third, and fourth brain ventricles that controls the entrance of substances into the cerebrospinal fluid from the blood" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0001614 ! blood vessel morphology

[Term]
id: MT:0000087
name: capillary morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the minute blood vessels that connect arterioles and venules" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
xref: MP:0003658
is_a: MT:0001614 ! blood vessel morphology

[Term]
id: MT:0000088
name: blood vessel integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the tubes that carry blood through the body" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "vascular integrity" RELATED []
relationship: part_of MT:0001614 ! blood vessel morphology

[Term]
id: MT:0000090
name: inferior vena cava integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
is_a: MT:0000118 ! vein integrity
relationship: part_of MT:0006063 ! inferior vena cava morphology

[Term]
id: MT:0000091
name: superior vena cava integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
is_a: MT:0000118 ! vein integrity
relationship: part_of MT:0006064 ! superior vena cava morphology

[Term]
id: MT:0000092
name: stria vascularis blood vessel integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the the blood vessels supplying the stria vascularis in the cochlea of the inner ear" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "integrity of the stial vasculature" RELATED []
synonym: "stria vascularis vascular integrity" RELATED []
synonym: "strial vascular integrity" RELATED []
is_a: MT:0000088 ! blood vessel integrity
relationship: part_of MT:0004368 ! stria vascularis blood vessel morphology

[Term]
id: MT:0000093
name: choroid blood vessel integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the blood vessels of the choroid" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
is_a: MT:0000088 ! blood vessel integrity
relationship: part_of MT:0006237 ! choroid blood vessel morphology

[Term]
id: MT:0000094
name: conjunctival blood vessel integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the blood vessel network of the conjunctiva" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "conjunctival vascular integrity" RELATED []
synonym: "integrity of the conjunctival vasculature" RELATED []
is_a: MT:0000088 ! blood vessel integrity
relationship: part_of MT:0006192 ! conjunctival blood vessel morphology

[Term]
id: MT:0000097
name: retina blood vessel integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the blood vessels supplying the retina" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "integrity of the retinal vasculature" RELATED []
synonym: "retinal vascular integrity" RELATED []
is_a: MT:0000088 ! blood vessel integrity
relationship: part_of MT:0002792 ! retina blood vessel morphology

[Term]
id: MT:0000098
name: vomer bone morphology
namespace: Trait.ontology
def: "missing triangular flat bone of the nasal septum" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal vomer bone" EXACT []
is_a: MT:0005274 ! viscerocranium morphology

[Term]
id: MT:0000099
name: aotic arch integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the portion of the descending aorta proceeding from the arch of the aorta and extending to the diaphram" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0004113 ! aortic arch morphology
relationship: part_of MT:0007044 ! aorta integrity

[Term]
id: MT:0000100
name: ethmoidal bone morphology
namespace: Trait.ontology
def: "defect in the midline facial bone that encloses the nasal cavity" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal ethmoid bone" EXACT []
synonym: "abnormal ethmoidal bone" EXACT []
is_a: MT:0005273 ! cranial base morphology
is_a: MT:0005552 ! orbital bone morphology

[Term]
id: MT:0000101
name: blood vessel elastic tissue integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the tissue that is found in the tunica media of the vessels wall and allows vessels to stretch" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "vascular elastic tissue integrity" RELATED []
relationship: part_of MT:0000088 ! blood vessel integrity
relationship: part_of MT:0006083 ! blood vessel elastic tissue morphology

[Term]
id: MT:0000102
name: nasal bone morphology
namespace: Trait.ontology
def: "any structural anomaly of either of two rectangular bone plates forming the bridge of the nose" [J:17489, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal nasal bone" EXACT []
is_a: MT:0005274 ! viscerocranium morphology

[Term]
id: MT:0000103
name: pulmonary vein integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the blood vessels that return oxygenated blood from the lungs to the left atrium of the heart" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "pulmonary venous integrity" RELATED []
is_a: MT:0000118 ! vein integrity
relationship: part_of MT:0002726 ! pulmonary vein morphology

[Term]
id: MT:0000104
name: sphenoid bone morphology
namespace: Trait.ontology
def: "malformed irregularly shaped bone of the base of the skull" [J:49840, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal sphenoid bone" EXACT []
is_a: MT:0005273 ! cranial base morphology
is_a: MT:0005552 ! orbital bone morphology

[Term]
id: MT:0000105
name: ossification of basisphenoid bone
namespace: Trait.ontology
def: "abnormal formation of the bone at the base of the sphenoid bone; arises from an ossification center independent of the remainder of the sphenoid bone" [J:49840, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000106 ! basisphenoid bone morphology

[Term]
id: MT:0000106
name: basisphenoid bone morphology
namespace: Trait.ontology
def: "any structural anomaly of part of the base of the cranium between the basioccipital and the presphenoid, which usually ossifies separately in the embryo or in the young, and becomes a part of the sphenoid in the adult; in many animals it persists as a separate bone between the basioccipital bone and the presphenoidal bone" [J:55583, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal basisphenoid bone" EXACT []
is_a: MT:0000104 ! sphenoid bone morphology

[Term]
id: MT:0000107
name: frontal bone morphology
namespace: Trait.ontology
def: "any structural anomaly of the bone forming the forehead and roof of the eye orbit" [J:17489, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal frontal bone" EXACT []
is_a: MT:0000076 ! calvaria morphology
is_a: MT:0005274 ! viscerocranium morphology
is_a: MT:0005552 ! orbital bone morphology

[Term]
id: MT:0000108
name: midline facial cleft
namespace: Trait.ontology
def: "incomplete merging or fusion of the tissues normally uniting to form the face" [J:49840, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002116 ! craniofacial bone morphology

[Term]
id: MT:0000109
name: parietal bone morphology
namespace: Trait.ontology
def: "malformed curved bone forming part of the vault of the cranium" [J:17489]
synonym: "abnormal parietal bone" EXACT []
is_a: MT:0000076 ! calvaria morphology

[Term]
id: MT:0000111
name: cleft palate
namespace: Trait.ontology
alt_id: MT:0000429
def: "congenital fissure of the tissues normally uniting to form the palate" [J:49840, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003755 ! palate

[Term]
id: MT:0000114
name: cleft chin
namespace: Trait.ontology
def: "incomplete fusion of the chin; usually a fissure" [J:42035, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000458 ! mandible morphology

[Term]
id: MT:0000116
name: tooth development
namespace: Trait.ontology
def: "anomalous formation of the teeth" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "tooth development abnormalities" EXACT []
is_a: MT:0002100 ! tooth morphology
is_a: MT:0002113 ! skeleton development
is_a: MT:0003935 ! craniofacial development

[Term]
id: MT:0000117
name: tooth primordium
namespace: Trait.ontology
def: "missing the cells that will give rise to teeth" [J:54637, tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "absence of tooth anlage" EXACT []
synonym: "absence of tooth primordium" EXACT []
is_a: MT:0000116 ! tooth development

[Term]
id: MT:0000118
name: vein integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the blood vessels that return blood to the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "venous integrity" RELATED []
is_a: MT:0000088 ! blood vessel integrity
is_a: MT:0002725 ! vein morphology

[Term]
id: MT:0000119
name: tooth eruption
namespace: Trait.ontology
def: "anomalies in the passage of a tooth through the alveolar process and perforation of the gums" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "tooth eruption abnormalities" EXACT []
is_a: MT:0002100 ! tooth morphology

[Term]
id: MT:0000120
name: malocclusion
namespace: Trait.ontology
def: "perturbations in the normal patterned arrangement of the teeth or alignment of the jaw, resulting in the incorrect position of biting or chewing surfaces of the upper and lower teeth" [J:61509]
synonym: "misaligned teeth" EXACT []
is_a: MT:0000438 ! skull morphology

[Term]
id: MT:0000121
name: cardiovascular development
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the morphology or physiology of the heart or blood vessels during their formation and differentiation" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0005385 ! cardiovascular system trait

[Term]
id: MT:0000122
name: blood vessel development
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the morphology or physiology of the vasculature during its formation and differentiation" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "vascular development" RELATED []
relationship: part_of MT:0000121 ! cardiovascular development

[Term]
id: MT:0000124
name: tooth number
namespace: Trait.ontology
def: "count of the bony structures of the upper and lower jaws used in mastication" [J:61295, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "absence of all teeth" EXACT []
is_a: MT:0002100 ! tooth morphology

[Term]
id: MT:0000125
name: heart tube morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the early embryonic heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0000267 ! heart development

[Term]
id: MT:0000126
name: tooth strength
namespace: Trait.ontology
def: "fragile and likely to break teeth" [J:61509]
is_a: MT:0002100 ! tooth morphology

[Term]
id: MT:0000127
name: molar integrity
namespace: Trait.ontology
def: "atrophy of the molars" [J:61509]
is_a: MT:0002689 ! molar morphology

[Term]
id: MT:0000128
name: growth of molars
namespace: Trait.ontology
def: "developmental delay of the growth of the molars" [J:17489]
is_a: MT:0000116 ! tooth development

[Term]
id: MT:0000129
name: ameloblast integrity
namespace: Trait.ontology
def: "a retrogressive impairment of function or destruction of the epithelial cells of the inner later of the enamel organ of the developing tooth" [J:61509, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "degeneration of ameloblasts" EXACT []
is_a: MT:0002650 ! ameloblast morphology

[Term]
id: MT:0000130
name: cancellous bone morphology
namespace: Trait.ontology
def: "structural anomaly of bone that has a lattice-like or spongy structure" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal cancellous bone" EXACT []
synonym: "abnormal spongy bone" EXACT []
synonym: "abnormal spongy spongiosa" EXACT []
synonym: "abnormal spongy substance" EXACT []
synonym: "abnormal substantia trabecularis" EXACT []
synonym: "abnormal trabecular bone" EXACT []
is_a: MT:0003795 ! bone structure

[Term]
id: MT:0000131
name: long bone epiphysis morphology
namespace: Trait.ontology
def: "the head of a developing long bone that is separated from the shaft by the epiphyseal plate" [J:61509]
synonym: "abnormal epiphysis" EXACT []
synonym: "abnormal long bone epiphysis morphology" EXACT []
is_a: MT:0002113 ! skeleton development
is_a: MT:0003723 ! long bone morphology

[Term]
id: MT:0000132
name: epiphysis width
namespace: Trait.ontology
def: "wider than normal part of the long bones that initially develops from a distinct ossification center than the shaft" [J:61295, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000131 ! long bone epiphysis morphology

[Term]
id: MT:0000133
name: long bone metaphysis morphology
namespace: Trait.ontology
def: "malformed conical section of bone between the epiphysis and diaphysis of the long bones" [J:61295, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal long bone metaphysis" EXACT []
synonym: "abnormal metaphysis" EXACT []
is_a: MT:0003723 ! long bone morphology

[Term]
id: MT:0000134
name: cortical bone thickness
namespace: Trait.ontology
def: "reduced or increased width of the superficial layer of compact bone" [J:58795, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "cortical bone thickness abnormalities" EXACT []
is_a: MT:0003796 ! cortical bone morphology

[Term]
id: MT:0000135
name: outflow tract morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the path through which blood exits the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0002127 ! cardiovascular system morphology

[Term]
id: MT:0000136
name: microglial cell morphology
namespace: Trait.ontology
def: "anomalous structure, number, or composition of the small neuroglial cells, possibly of mesodermal origin, which may become phagocytic, in areas of neural damage or inflammation" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:71688]
is_a: MT:0000952 ! CNS glia morphology

[Term]
id: MT:0000137
name: vertebrae morphology
namespace: Trait.ontology
alt_id: MT:0001538
def: "malformed bony segment of the spinal column" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_pig
synonym: "abnormal vertebrae" EXACT []
synonym: "vertebra defect" EXACT []
is_a: MT:0002114 ! axial skeleton morphology

[Term]
id: MT:0000138
name: vertebrae number
namespace: Trait.ontology
def: "missing bony segments of the spinal column" [J:35802]
subset: slim_cattle
subset: slim_pig
synonym: "absence of vertebrae" EXACT []
is_a: MT:0000137 ! vertebrae morphology

[Term]
id: MT:0000139
name: transverse process morphology
namespace: Trait.ontology
def: "form or structure of the bony protrusion on either side of the arch of a thoracic vertebrae" [J:62022, J:62023]
synonym: "absence of transverse processes" EXACT []
is_a: MT:0000137 ! vertebrae morphology

[Term]
id: MT:0000140
name: pedicle morphology
namespace: Trait.ontology
def: "form or structure of part of the posteriorlateral vertebral arch of a thoracic vertebrae" [J:62022, J:62023]
is_a: MT:0000137 ! vertebrae morphology

[Term]
id: MT:0000141
name: vertebral body morphology
namespace: Trait.ontology
def: "malformed main portion of the vertebra anterior to the vertebral canal" [J:55583, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal vertebral bodies" EXACT []
is_a: MT:0000137 ! vertebrae morphology

[Term]
id: MT:0000142
name: ear thickness
namespace: Trait.ontology
def: "straight line distance from the exterior surface to the interior surface of the outer ear" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000017 ! ear size

[Term]
id: MT:0000143
name: immature B cell number
namespace: Trait.ontology
def: "number of the cells of the B lymphocyte lineage that have undergone VDJ rearrangement of the heavy chain and V-J rearrangement of the light chain; these cells express IgM on the cell surface but have not yet been selected for self-reactivity" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005022 ! immature B cell morphology/development

[Term]
id: MT:0000148
name: shoulder/ pelvic girdle morphology
namespace: Trait.ontology
alt_id: MT:0001540
def: "anomalous structure of the bones of the shoulder or of the bones of the pelvis by which the limbs attach to the axial skeleton " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal shoulder/ pelvic girdle" EXACT []
synonym: "shoulder/ pelvic girdle defect" EXACT []
is_a: MT:0005508 ! skeleton morphology

[Term]
id: MT:0000149
name: scapula morphology
namespace: Trait.ontology
def: "malformation of either or both of the large, flat bones of the back part of the shoulder" [J:13049]
synonym: "abnormal scapula" EXACT []
is_a: MT:0000148 ! shoulder/ pelvic girdle morphology

[Term]
id: MT:0000150
name: rib morphology
namespace: Trait.ontology
def: "malformed bones forming the bony wall of the chest" [J:50311, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal ribs" EXACT []
synonym: "rib defect" EXACT []
is_a: MT:0002114 ! axial skeleton morphology

[Term]
id: MT:0000151
name: atrioventricular canal partioning
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the process by which the right and left sides of the heart become separated" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0000267 ! heart development

[Term]
id: MT:0000152
name: proximal rib morphology
namespace: Trait.ontology
def: "missing part of rib structures near the spine, ribs do not contact vertebrae" [J:62022, J:62023]
is_a: MT:0000150 ! rib morphology

[Term]
id: MT:0000155
name: rib attachment
namespace: Trait.ontology
def: "pattern, form, or structure of rib attachments to the vertebral column or to the sternum" [J:19212]
is_a: MT:0000150 ! rib morphology

[Term]
id: MT:0000156
name: memory B cell number
namespace: Trait.ontology
def: "number of cells of the B lymphocyte lineage that do not secrete antibody after an initial contact with antigen, but can be rapidly activated after a second challenge with the same antigen" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002440 ! memory B cell morphology/development

[Term]
id: MT:0000157
name: sternum morphology
namespace: Trait.ontology
def: "malformed long flat bone of the chest; articulates with clavicle and first seven rib pairs" [J:19212, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal sternum" EXACT []
synonym: "sternum defect" EXACT []
is_a: MT:0002114 ! axial skeleton morphology

[Term]
id: MT:0000159
name: xiphoid process morphology
namespace: Trait.ontology
def: "malformed posterior tip of the sternum" [J:42932, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "xiphoid process defect" EXACT []
is_a: MT:0000157 ! sternum morphology

[Term]
id: MT:0000160
name: kyphosis
namespace: Trait.ontology
alt_id: MT:0000068
def: "forward curvature of the spine, characterized by extensive flexion. " [cml:Cathleen M. Lutz_Mouse Genome Informatics Curator, J:62023, J:66943, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "humpback" EXACT []
synonym: "hunchback" EXACT []
is_a: MT:0004174 ! spine curvature

[Term]
id: MT:0000161
name: scoliosis
namespace: Trait.ontology
alt_id: MT:0000070
def: "lateral and rotational curvature of the spine" [J:53770, J:66943, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0004174 ! spine curvature

[Term]
id: MT:0000162
name: lordosis
namespace: Trait.ontology
def: "anteriorly convex curvature of the spine, \"saddle back\" " [J:62022, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0004174 ! spine curvature

[Term]
id: MT:0000163
name: cartilage morphology
namespace: Trait.ontology
def: "anomalous structure or development of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the thorax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal cartilage" EXACT []
is_a: MT:0005508 ! skeleton morphology

[Term]
id: MT:0000164
name: cartilage development
namespace: Trait.ontology
def: "anomalous formation of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the thorax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal cartilage formation" EXACT []
is_a: MT:0000163 ! cartilage morphology
is_a: MT:0002113 ! skeleton development

[Term]
id: MT:0000165
name: hypertrophic chondrocyte zone morphology
namespace: Trait.ontology
def: "anomaly of the cartilage cell matrix layer " [J:58795, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000164 ! cartilage development
is_a: MT:0003055 ! epiphyseal plate morphology

[Term]
id: MT:0000166
name: chondrocyte morphology
namespace: Trait.ontology
def: "anomalous structure, organization, or differentiation of nondividing cartilage cells" [J:40203, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal chondrocytes" EXACT []
is_a: MT:0000163 ! cartilage morphology

[Term]
id: MT:0000167
name: chondrocyte number
namespace: Trait.ontology
def: "fewer than normal numbers of nondividing cartilage cells" [J:61509, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000166 ! chondrocyte morphology

[Term]
id: MT:0000168
name: bone marrow development
namespace: Trait.ontology
def: "malformation or anomalous differentiation of the soft, pulpy tissue filling the medullary cavities of bones" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal bone marrow formation/ structure" EXACT []
is_a: MT:0002113 ! skeleton development

[Term]
id: MT:0000172
name: bone marrow cell number
namespace: Trait.ontology
def: "increased or decreased number of cells that make up the core cavities of bones when compared to controls" [tc:Teresa Chu_Mouse Genome Informatics Curator]
is_a: MT:0002398 ! bone marrow cell morphology/development

[Term]
id: MT:0000176
name: bone marrow occupied by adipocytes
namespace: Trait.ontology
def: "anomalous appearance of fat-forming cells in the bone marrow" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0000168 ! bone marrow development

[Term]
id: MT:0000179
name: blood chemistry
namespace: Trait.ontology
alt_id: MT:0001546
def: "anomalous concentrations of proteins, minerals, nutrients, gases, or other substances in the blood" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "blood chemistry abnormalities" EXACT []
is_a: MT:0005428 ! clinical chemistry

[Term]
id: MT:0000180
name: circulating cholesterol level
namespace: Trait.ontology
def: "anomalous concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
synonym: "abnormal cholesterol level" EXACT []
is_a: MT:0003947 ! cholesterol level
is_a: MT:0003949 ! circulating lipid level

[Term]
id: MT:0000181
name: circulating LDL cholesterol level
namespace: Trait.ontology
def: "anomalous concentration in the blood of low density lipoprotein, which normally transports cholesterol to tissues other than the liver" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal LDL cholesterol level" EXACT []
is_a: MT:0000180 ! circulating cholesterol level

[Term]
id: MT:0000184
name: circulating HDL cholesterol level
namespace: Trait.ontology
alt_id: MT:0001555
def: "anomalous concentration in the blood of high density lipoprotein; this molecule transports cholesterol to the liver for excretion in bile" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal HDL cholesterol level" EXACT []
synonym: "Abnormal HDL Levels" EXACT []
is_a: MT:0000180 ! circulating cholesterol level

[Term]
id: MT:0000187
name: triglyceride level
namespace: Trait.ontology
alt_id: MT:0001551
def: "anomalous concentration of this molecule, glycerol esterified at each of its three hydroxyl groups by a fatty acid; triglyceride is an important molecule for storage of fatty acids in adipose tissue" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
synonym: "abnormal triacylglycerol level" EXACT []
is_a: MT:0001547 ! lipid level

[Term]
id: MT:0000188
name: circulating glucose level
namespace: Trait.ontology
alt_id: MT:0001557
def: "anomalous concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_chkn
subset: slim_pig
synonym: "abnormal blood glucose level" EXACT []
is_a: MT:0002078 ! glucose homeostasis

[Term]
id: MT:0000192
name: mineral level
namespace: Trait.ontology
alt_id: MT:0001561
def: "anomalous concentration of any inorganic substance that has importance in body functions" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005636 ! mineral homeostasis

[Term]
id: MT:0000199
name: circulating albumin level
namespace: Trait.ontology
alt_id: MT:0001568
def: "aberrant concentration in the blood of this most abundant of the plasma proteins " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal albumin level" EXACT []
synonym: "analbuminemia" EXACT []
is_a: MT:0005416 ! circulating protein level

[Term]
id: MT:0000202
name: circulating alkaline phosphatase level
namespace: Trait.ontology
alt_id: MT:0001571
def: "anomalous concentration in the blood of this enzyme, which hydrolyzes orthophosphoric monoesters; low levels are seen in cases of hypophosphatasia" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal alkaline phosphatase activity" EXACT []
synonym: "abnormal alkaline phosphatase level" EXACT []
synonym: "abnormal AP level" EXACT []
synonym: "abnormal circulating ALP levels" EXACT []
xref: GO:0004035
is_a: MT:0001570 ! circulating enzyme level

[Term]
id: MT:0000203
name: circulating aspartate transaminase level
namespace: Trait.ontology
alt_id: MT:0001572
def: "anomalous concentration in the blood of this enzyme, which catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid; aids in diagnosis of viral hepatitis and myocardial infarction" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal aspartate aminotransferase level" EXACT []
synonym: "abnormal aspartate transaminase level" EXACT []
synonym: "abnormal AST level" EXACT []
is_a: MT:0001570 ! circulating enzyme level

[Term]
id: MT:0000217
name: white blood cell count
namespace: Trait.ontology
alt_id: MT:0001587
def: "anomalies in the number of leukocytes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_cattle
subset: slim_pig
synonym: "abnormal WBC cell" EXACT []
synonym: "abnormal white blood cell number" EXACT []
synonym: "leukocyte count abnormalities" EXACT []
synonym: "white blood cell count abnormalities" EXACT []
synonym: "white blood cell number abnormalities" EXACT []
is_a: MT:0000716 ! immune system cell morphology
is_a: MT:0002429 ! blood cell morphology/development

[Term]
id: MT:0000221
name: WBC count
namespace: Trait.ontology
def: "fewer than normal numbers of WBCs" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_cattle
subset: slim_pig
synonym: "decreased leukocyte count" EXACT []
synonym: "decreased WBC number" EXACT []
synonym: "leukocytopenia" EXACT []
synonym: "leukopenia" EXACT []
synonym: "lymphopenia" EXACT []
is_a: MT:0000217 ! white blood cell count

[Term]
id: MT:0000222
name: neutrophil count
namespace: Trait.ontology
def: "fewer than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_pig
synonym: "decreased neutrophil number" EXACT []
synonym: "neutropenia" EXACT []
synonym: "segmented neutrophil count" EXACT []
is_a: MT:0000334 ! granulocyte number
is_a: MT:0002415 ! neutrophil morphology/development

[Term]
id: MT:0000223
name: monocyte count
namespace: Trait.ontology
def: "fewer than normal monocyte numbers" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "decreased monocyte number" EXACT []
synonym: "monocytopenia" EXACT []
is_a: MT:0000221 ! WBC count
is_a: MT:0002620 ! monocyte morphology/development

[Term]
id: MT:0000226
name: mean corpuscular volume
namespace: Trait.ontology
alt_id: MT:0001590
def: "deviation from normal for the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
comment: MCV is calculated by dividing the hematocrit by the total number of RBCs and multiplying this number by ten (10). This was found on medfriendly.com. cwg 3/10/03
subset: slim_chkn
synonym: "abnormal MCV" EXACT []
synonym: "abnormal mean cell volume" EXACT []
is_a: MT:0002124 ! red blood cell

[Term]
id: MT:0000228
name: thrombopoiesis
namespace: Trait.ontology
alt_id: MT:0000211
alt_id: MT:0000227
alt_id: MT:0001583
alt_id: MT:0001591
alt_id: MT:0001592
alt_id: MT:0002448
def: "abnormal development of the non-nucleated cells of the blood (platelets, thrombocytes) involved in blood coagulation" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal platelet development" EXACT []
synonym: "abnormal platelet morphology/development" EXACT []
synonym: "abnormal platelets" EXACT []
synonym: "platelet abnormalities" EXACT []
synonym: "platelet development abnormalities" EXACT []
synonym: "thrombocyte abnormalities" EXACT []
is_a: MT:0002123 ! hematopoiesis
is_a: MT:0002417 ! megakaryocyte morphology/development

[Term]
id: MT:0000229
name: megakaryocyte differentiation
namespace: Trait.ontology
alt_id: MT:0001593
def: "atypical process of formation and development these very large bone marrow cells which release mature platelets" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0000228 ! thrombopoiesis

[Term]
id: MT:0000230
name: blood pressure
namespace: Trait.ontology
alt_id: MT:0001594
alt_id: MT:0002129
def: "any measurable characteristic of the tension of the blood within the systemic arteries" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
xref: MGI:2173589
is_a: MT:0001544 ! cardiovascular system physiology

[Term]
id: MT:0000233
name: blood flow velocity
namespace: Trait.ontology
alt_id: MT:0001597
def: "rate of flow of the blood through vessels" [ms:mary shimoyama]
is_a: MT:0002128 ! blood circulation

[Term]
id: MT:0000237
name: blood cell number
namespace: Trait.ontology
def: "fewer than the normal numbers of the various types of blood cells" [J:60630]
synonym: "reduction in hematopoietic cell types" EXACT []
synonym: "reduction in hemopoietic cell types" EXACT []
is_a: MT:0002123 ! hematopoiesis

[Term]
id: MT:0000239
name: myeloid colony forming progenitor cell number
namespace: Trait.ontology
def: "lack of precursors of the myeloid cell types" [J:60630, tc:Teresa Chu_Mouse Genome Informatics Curator]
is_a: MT:0002123 ! hematopoiesis

[Term]
id: MT:0000240
name: extramedullary hematopoiesis
namespace: Trait.ontology
def: "formation and development of blood cells outside the bone marrow, e.g., in the spleen, liver, or lymph nodes" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "EMH" EXACT []
synonym: "extramedullary hemopoiesis" EXACT []
is_a: MT:0002123 ! hematopoiesis

[Term]
id: MT:0000243
name: myoclonus
namespace: Trait.ontology
def: "involuntary shock-like contractions, variable in rhythm and amplitude, followed by relaxation, of a muscle or a group of muscles; generally due to a central nervous system lesion" [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000743 ! muscle spasms

[Term]
id: MT:0000245
name: erythropoiesis
namespace: Trait.ontology
alt_id: MT:0001608
def: "atypical process of red blood cell formation" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8, tc:Teresa Chu_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
synonym: "abnormal erythrocytopoiesis" EXACT []
synonym: "erythropoiesis abnormalities" EXACT []
is_a: MT:0002123 ! hematopoiesis

[Term]
id: MT:0000247
name: IL-10 physiology
namespace: Trait.ontology
def: "functional anomaly of this factor that is a co-regulator of mast cell growth and produced by T and B cells" [MeSH:National Library of Medicine_Medical Subject Headings, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "interleukin 10" EXACT []
is_a: MT:0002529 ! interleukin physiology

[Term]
id: MT:0000248
name: macrocytosis
namespace: Trait.ontology
alt_id: MT:0001610
def: "condition in which erythrocytes are larger than normal in size" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "macrocythemia" EXACT []
synonym: "megalocythemia" EXACT []
synonym: "megalocytosis" EXACT []
synonym: "megaolcytosis" EXACT []
is_a: MT:0002447 ! erythrocyte morphology

[Term]
id: MT:0000249
name: blood vessel physiology
namespace: Trait.ontology
synonym: "vascular physiology" EXACT []
is_a: MT:0001544 ! cardiovascular system physiology

[Term]
id: MT:0000250
name: vasoconstriction
namespace: Trait.ontology
alt_id: MT:0001612
def: "narrowing of the blood vessels" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition"]
is_a: MT:0000249 ! blood vessel physiology

[Term]
id: MT:0000253
name: plasma cell number
namespace: Trait.ontology
def: "number of the specialized forms of B-lymphocytes which produce and secrete immunoglobulin" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002439 ! plasma cell morphology/development

[Term]
id: MT:0000254
name: cerebrospinal fluid volume
namespace: Trait.ontology
def: "amount of the serumlike fluid that circulates through the ventricles of the brain, the cavity of the spinal cord, and the subarachnoid space, functioning in shock absorption." [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003632 ! nervous system morphology

[Term]
id: MT:0000256
name: echinocytosis
namespace: Trait.ontology
def: "a state in which the red blood cells have multiple small projections appearing over the cell circumference resembling a small burr or a sea urchin" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:82330, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "burr erythrocyte" EXACT []
synonym: "crenation" EXACT []
synonym: "echinosis" EXACT []
is_a: MT:0002447 ! erythrocyte morphology

[Term]
id: MT:0000266
name: cardiac morphology
namespace: Trait.ontology
alt_id: MT:0000271
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the organ that pumps blood through the body" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
subset: slim_chkn
subset: slim_pig
synonym: "heart morphology" RELATED []
xref: GO:0007505
xref: MP:0000266
is_a: MT:0002127 ! cardiovascular system morphology

[Term]
id: MT:0000267
name: heart development
namespace: Trait.ontology
alt_id: MT:0001624
def: "any measurable or observable characteristic related to the morphology or physiology of the heart during its formation and differentiation" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "cardiac development" EXACT []
xref: GO:0007507
xref: MP:0000267
relationship: part_of MT:0000121 ! cardiovascular development

[Term]
id: MT:0000268
name: vibrissae number
namespace: Trait.ontology
def: "number of whiskers" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002098 ! vibrissae morphology

[Term]
id: MT:0000269
name: heart tube looping morphogenesis
namespace: Trait.ontology
def: "any measurable or observable characteristics pertaining to the process by which the embryonic heart tube bends to transform from a straight tube into the final folded configuration of the adult heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "cardiac looping morphogenesis" RELATED []
relationship: part_of MT:0000267 ! heart development

[Term]
id: MT:0000270
name: heart tube integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the structural completeness or structural soundness of the early embryonic heart" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
relationship: part_of MT:0000125 ! heart tube morphology

[Term]
id: MT:0000272
name: aorta morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the main trunk of the systemic arteries" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
xref: MP:0000272
is_a: MT:0002191 ! artery morphology

[Term]
id: MT:0000276
name: right ventricle cell size
namespace: Trait.ontology
def: "the physical dimensions, proportions, magnitude, or extent of the cells in the right lower chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "right ventricular cell size" RELATED []
is_a: MT:0001625 ! heart cell size
relationship: part_of MT:0003920 ! right ventricle morphology

[Term]
id: MT:0000277
name: heart shape
namespace: Trait.ontology
def: "any measurable or observable characterisic of the form of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "cardiac shape" EXACT []
relationship: part_of MT:0000266 ! cardiac morphology

[Term]
id: MT:0000278
name: heart muscle fiber integrity
namespace: Trait.ontology
alt_id: MT:0002994
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the multinucleated muscle cells of the heart" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "cardiac muscle fiber integrity" RELATED []
synonym: "myocardial fiber integrity" RELATED []
relationship: part_of MT:0000061 ! heart muscle fiber morphology
relationship: part_of MT:0000073 ! heart muscle integrity
relationship: part_of MT:0004087 ! muscle fiber morphology

[Term]
id: MT:0000281
name: ventricle septum integrity
namespace: Trait.ontology
alt_id: MT:0005484
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the wall between the two lower chambers of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "interventricular septum integrity" RELATED []
synonym: "ventricular septal morphology" RELATED []
xref: MP:0000281
relationship: part_of MT:0000053 ! heart integrity
relationship: part_of MT:0007082 ! ventricle septum morphology

[Term]
id: MT:0000282
name: atrium septum integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the wall between the two upper chambers of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "atrial septal integrity" RELATED []
relationship: part_of MT:0000053 ! heart integrity
relationship: part_of MT:0007081 ! atrium septum morphology

[Term]
id: MT:0000284
name: right ventricle integrity
namespace: Trait.ontology
alt_id: MT:0000283
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the right lower chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0000053 ! heart integrity
relationship: part_of MT:0003920 ! right ventricle morphology

[Term]
id: MT:0000285
name: heart valve morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern  of the membranous folds of the heart that prevent reflux of fluid" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "cardiac valve morphology" RELATED []
xref: MP:0000285
relationship: part_of MT:0000266 ! cardiac morphology

[Term]
id: MT:0000286
name: mitral valve integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the valve between the left atrium and the left ventricle of the heart" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0002745 ! atrioventricular valve integrity
relationship: part_of MT:0000033 ! mitral valve morphology

[Term]
id: MT:0000288
name: pericardium morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the fibroserous membrane covering the heart and beginning of the great vessels" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "pericardial morphology" EXACT []
xref: GO:0007513
relationship: part_of MT:0000266 ! cardiac morphology

[Term]
id: MT:0000297
name: endocardial cushion integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the structural completeness or structural soundness of the mounds of embryonic connective tissue that bulge into the embryonic atrioventricular canal; these mounds fuse to form the valves between the right and left atrioventricular orifices" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
xref: GO:0007505
relationship: part_of MT:0007001 ! endocardial cushion morphology

[Term]
id: MT:0000304
name: cardiac stroke volume
namespace: Trait.ontology
alt_id: MT:0001628
def: "amount of blood pushed into the aorta with each beat of the heart" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0002128 ! blood circulation

[Term]
id: MT:0000306
name: umbilical artery integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the blood vessel of the umbilical cord" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0001725 ! umbilical cord morphology
is_a: MT:0003410 ! artery integrity

[Term]
id: MT:0000307
name: blood-inner ear barrier function
namespace: Trait.ontology
def: "function of the group of barriers and transport systems which regulate the transport of various substances from blood to inner ear tissue and maintain the microhomeostasis and functional integrity of the inner ear; the endothelial cells of the inner ear blood capillaries, linked to each other by tight junctions, represent the main component of the blood-inner ear barrier" [MGI:anna "Anna Anagnostopoulos, Mouse Genome Informatics Curator"]
is_a: MT:0000249 ! blood vessel physiology
is_a: MT:0003878 ! ear physiology

[Term]
id: MT:0000313
name: cell death
namespace: Trait.ontology
alt_id: MT:0001647
def: "anomalous cessation of function at the cellular level" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal cellular death" EXACT []
is_a: MT:0005621 ! cell physiology

[Term]
id: MT:0000314
name: schistocytosis
namespace: Trait.ontology
def: "the appearance of poikilocytes in the blood that owe their abnormal shape to fragmentation occurring as the cells flow through damaged small vessels" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:82330]
synonym: "schizocytosis" EXACT []
is_a: MT:0002643 ! poikilocytosis

[Term]
id: MT:0000315
name: urine hemoglobin level
namespace: Trait.ontology
def: "the presence of hemoglobin in the urine, including certain closely related pigments that are formed from slight alteration of the hemoglobin molecule" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:82330]
synonym: "hemoglobinuria" RELATED []
is_a: MT:0005160 ! urine protein level

[Term]
id: MT:0000316
name: cellular necrosis
namespace: Trait.ontology
def: "pathologic death of cells, usually from irreversible damage" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001651 ! necrosis

[Term]
id: MT:0000317
name: cell number
namespace: Trait.ontology
def: "anomalous numbers of cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0005384 ! cellular trait

[Term]
id: MT:0000319
name: endolymph physiology
namespace: Trait.ontology
def: "processes involved in the production (volume) or ionic homeostasis of the fluid contained within the membranous labyrinth of the inner ear" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0003878 ! ear physiology

[Term]
id: MT:0000327
name: hemosiderinuria
namespace: Trait.ontology
def: "the presence of hemosiderin in the urine; hemosiderin is an intracellular storage form of iron, found in the form of pigmented yellow to brown granules consisting of a complex of ferric hydroxides, polysaccharides, and proteins with an iron content of about 33 per cent by weight" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:82330]
is_a: MT:0001757 ! urine chemistry

[Term]
id: MT:0000330
name: endolymph production
namespace: Trait.ontology
def: "secretion of the fluid that is normally contained within the membranous labyrinth of the inner ear" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000319 ! endolymph physiology

[Term]
id: MT:0000332
name: hemoglobinemia
namespace: Trait.ontology
def: "the presence of free hemoglobin in the blood plasma, an indication of significant intravascular hemolysis" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:82330]
is_a: MT:0005416 ! circulating protein level

[Term]
id: MT:0000334
name: granulocyte number
namespace: Trait.ontology
alt_id: MT:0000723
def: "fewer than expected number of leukocytes that have abundant granules in the cytoplasm: basophils, neutrophils, or eosinophils" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_pig
synonym: "decreased granulocyte number" EXACT []
synonym: "granulocytopenia" EXACT []
is_a: MT:0000221 ! WBC count
is_a: MT:0002441 ! granulocyte morphology/development

[Term]
id: MT:0000336
name: mast cell number
namespace: Trait.ontology
def: "fewer than expected number of the granulated cells found in most tissues and which contain large amounts of histamine and heparin in granules" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0000359 ! mast cell morphology
is_a: MT:0002607 ! basophil count

[Term]
id: MT:0000340
name: perilymph physiology
namespace: Trait.ontology
def: "production (volume) or ionic homeostasis of the fluid contained within the osseous labyrinth, surrounding and protecting the membranous labyrinth" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0003878 ! ear physiology

[Term]
id: MT:0000341
name: bile color
namespace: Trait.ontology
def: "a change in the color of the bile from the normal yellowish brown or green " [J:80519]
is_a: MT:0005085 ! gall bladder physiology

[Term]
id: MT:0000344
name: Cajal-Retzius cell morphology
namespace: Trait.ontology
alt_id: MT:0000793
alt_id: MT:0000817
def: "structure of the distinct population of large, bipolar cells, distributed in a continuous band along the marginal zone of the cortex extending to the molecular layer of the dentate gyrus" [J:60896, tc:Teresa Chu_Mouse Genome Informatics Curator]
is_a: MT:0000792 ! cortical marginal zone morphology
is_a: MT:0000812 ! dentate gyrus morphology
is_a: MT:0002882 ! neuron

[Term]
id: MT:0000348
name: aerobic fitness
namespace: Trait.ontology
def: "any change in the metabolism resulting in an altered ability to do physical work; for example, alterations in running capacity" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, RGD:Rat Genome Database submission]
is_a: MT:0002121 ! metabolism

[Term]
id: MT:0000350
name: cell proliferation
namespace: Trait.ontology
def: "anomalous growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005621 ! cell physiology

[Term]
id: MT:0000353
name: vestibular system physiology
namespace: Trait.ontology
def: "processes pertinent to the function of he sensory system responsible for the sense of head position and movement of the body through space" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0003878 ! ear physiology

[Term]
id: MT:0000354
name: linear vestibular evoked potential
namespace: Trait.ontology
def: "biphasic response elicited by linear acceleration transients (usually jerk pulses to an animal's head); normally, this response is measured by electrophysiological activity of the peripheral vestibular nerve; this assesses the function of the gravity receptor system including the utricles and saccules of the inner ear" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "linear vestibular compound action potentials" RELATED []
synonym: "VeSPs" RELATED []
is_a: MT:0000353 ! vestibular system physiology

[Term]
id: MT:0000355
name: vestibular evoked myogenic potential
namespace: Trait.ontology
def: "biphasic response elicited by loud clicks or tone bursts recorded from the tonically contracted sternocleidomastoid muscle; normally, acoustic stimulation of the saccule gives rise to a vestibulocollic reflex, the output of which can be measured in the neck as inhibition of activity in the ipsilateral sternocleidomastoid muscle; VEMP testing provides diagnostic information about saccular and/or inferior vestibular nerve function (assessment of balance disorders)" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "VEMP(s)" RELATED []
is_a: MT:0000353 ! vestibular system physiology

[Term]
id: MT:0000356
name: vestibulocollic reflex
namespace: Trait.ontology
is_a: MT:0000353 ! vestibular system physiology
is_a: MT:0001961 ! reflex

[Term]
id: MT:0000357
name: limb number
namespace: Trait.ontology
def: "average count of limbs" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002109 ! limb morphology

[Term]
id: MT:0000358
name: cell content/ morphology
namespace: Trait.ontology
alt_id: MT:0000311
alt_id: MT:0000312
def: "structural anomalies of the minute protoplasmic masses that make up organized tissues and which are the fundamental structural and functional units of living organisms" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal cell" EXACT []
synonym: "cell abnormalities" EXACT []
synonym: "cellular abnormalities" EXACT []
is_a: MT:0005384 ! cellular trait

[Term]
id: MT:0000359
name: mast cell morphology
namespace: Trait.ontology
def: "anomalous structure of these granulated cells found in most tissues, but most abundantly in skin and gastrointestinal tract" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0005462 ! mast cell morphology/development

[Term]
id: MT:0000360
name: metachromatic granule number
namespace: Trait.ontology
def: "count of intracellular storage compartments that stain a different color than that of the dye used" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000359 ! mast cell morphology

[Term]
id: MT:0000361
name: mast cell protease content
namespace: Trait.ontology
def: "decreased amounts of proteolytic enzymes stored in mast cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "reduced storage of mast-cell proteases" EXACT []
is_a: MT:0000359 ! mast cell morphology

[Term]
id: MT:0000362
name: histamine content
namespace: Trait.ontology
def: "decreased amounts of this potent vasoactive peptide stored in mast cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "reduced storage of histamine" EXACT []
is_a: MT:0000359 ! mast cell morphology

[Term]
id: MT:0000363
name: cochlear microphonics
namespace: Trait.ontology
def: "bioelectric potentials produced by the hair cells of the organ of Corti in response to sound; the cochlear microphonic (CM) is an electric response dominated by OHC receptor potentials from the basal turn of the cochlea and provides a measure of transducer function in OHCs; in an active ear, CM waveforms show post-stimulus ringing (i.e. a cochlear echo) whereas in a passive ear system, CM decays at the cessation of the tone burst" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004412 ! cochlear potential
is_a: MT:0004434 ! cochlear outer hair cell physiology

[Term]
id: MT:0000365
name: hearing electrophysiology
namespace: Trait.ontology
def: "auditory function as it relates to electrical phenomena" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002104 ! hearing physiology

[Term]
id: MT:0000366
name: brainstem auditory evoked potential
namespace: Trait.ontology
def: "the electrical activity generated in response to short tone bursts; may be used to evaluate sensorineural hearing function" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "ABRs" RELATED []
synonym: "BAEPs" RELATED []
synonym: "brainstem evoked responses" RELATED []
is_a: MT:0000365 ! hearing electrophysiology
is_a: MT:0000483 ! sensorineural hearing function

[Term]
id: MT:0000367
name: coat/ hair morphology
namespace: Trait.ontology
def: "anomalous color, structure, growth, or texture of the hair" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_pig
synonym: "abnormal coat/ hair" EXACT []
synonym: "coat/ hair abnormalities" EXACT []
synonym: "coat/ hair anomalies" EXACT []
is_a: MT:0005393 ! skin/coat/nails/feathers trait

[Term]
id: MT:0000370
name: head blaze
namespace: Trait.ontology
def: "the appearance of a stripe of white fur on the head" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002075 ! coat color

[Term]
id: MT:0000372
name: irregular coat pigmentation
namespace: Trait.ontology
def: "uneven coloration of the hair" [J:65030]
is_a: MT:0002075 ! coat color

[Term]
id: MT:0000373
name: belly spot
namespace: Trait.ontology
def: "the appearance of a round area of white fur on the belly" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002938 ! white spotting

[Term]
id: MT:0000374
name: cochlear frequency tuning
namespace: Trait.ontology
def: "the frequency resolution of the cochlea, normally determined by the passive mechanical properties of the basilar membrane and active feedback from the outer hair cells which detect and amplify sound-induced basilar membrane motions" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "cochlear tuning" RELATED []
synonym: "frequency resolution of the cochlea" RELATED []
is_a: MT:0000365 ! hearing electrophysiology
is_a: MT:0000483 ! sensorineural hearing function

[Term]
id: MT:0000375
name: hair follicle structure
namespace: Trait.ontology
def: "anomalies of the basic architecture of the invagination of the epidermis from which the hair shaft develops" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "hair follicle structure abnormalities" EXACT []
is_a: MT:0002076 ! hair follicle structure/orientation

[Term]
id: MT:0000376
name: folliculitis
namespace: Trait.ontology
def: "inflammatory reaction in hair follicles " [J:65146, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001846 ! tissue specific inflammatory response
is_a: MT:0002076 ! hair follicle structure/orientation

[Term]
id: MT:0000379
name: hair follicle number
namespace: Trait.ontology
def: "number of the epidermal invaginations from which the hair shaft develops" [J:15108]
is_a: MT:0002076 ! hair follicle structure/orientation

[Term]
id: MT:0000382
name: hair follicle differentiation
namespace: Trait.ontology
def: "arrest of or retarded differentiation of the epidermal invaginations from which the hair shaft develops" [J:61790, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000375 ! hair follicle structure

[Term]
id: MT:0000383
name: hair follicle orientation
namespace: Trait.ontology
def: "misaligned hair follicles; hair follicles that do not orient in a typical pattern" [J:47620]
is_a: MT:0002076 ! hair follicle structure/orientation

[Term]
id: MT:0000384
name: hair follicle pattern
namespace: Trait.ontology
def: "twisted or contorted configuration of the arrangement of hair follicles in the skin" [J:56777]
is_a: MT:0002076 ! hair follicle structure/orientation

[Term]
id: MT:0000385
name: hair follicle size
namespace: Trait.ontology
def: "follicles that have swollen or expanded from the skin" [J:53379]
is_a: MT:0000375 ! hair follicle structure

[Term]
id: MT:0000386
name: hair follicle root sheath morphology
namespace: Trait.ontology
def: "anomalies of the epidermally derived layer surrounding the hair follicle; innermost of two layers" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "hair follicle root sheath abnormalities" EXACT []
is_a: MT:0000375 ! hair follicle structure

[Term]
id: MT:0000387
name: inner root sheath cell organization
namespace: Trait.ontology
def: "disordered enveloping layer of cells of the hair follicle; comprises the cuticle of the inner roots" [J:56777]
is_a: MT:0000386 ! hair follicle root sheath morphology

[Term]
id: MT:0000389
name: outer root sheath cell organization
namespace: Trait.ontology
def: "disordered enveloping layer of cells of the hair follicle; surrounds inner root and is continuous with basal and spinous layers of the epidermis" [J:56777]
is_a: MT:0000386 ! hair follicle root sheath morphology

[Term]
id: MT:0000390
name: matrix sheath cell organization
namespace: Trait.ontology
def: "disordered layer of matrix cells of the hair follicle" [J:56777]
is_a: MT:0000386 ! hair follicle root sheath morphology

[Term]
id: MT:0000391
name: onset of hair follicle generation
namespace: Trait.ontology
def: "early onset of hair follicle development" [J:39752]
is_a: MT:0002076 ! hair follicle structure/orientation

[Term]
id: MT:0000393
name: persistent hair follicle morphogenesis
namespace: Trait.ontology
def: "continuous induction of de novo hair follicles in the epidermis" [J:51296]
is_a: MT:0002076 ! hair follicle structure/orientation

[Term]
id: MT:0000394
name: hair follicle melanin granule number
namespace: Trait.ontology
def: "count of the pigment polymers in the hair follicles" [J:18378]
is_a: MT:0005072 ! hair follicle melanin granule morphology

[Term]
id: MT:0000395
name: hair types
namespace: Trait.ontology
def: "malformed subsets of types of hairs" [J:47620]
is_a: MT:0000367 ! coat/ hair morphology

[Term]
id: MT:0000396
name: curvature of hairs
namespace: Trait.ontology
def: "distinct C- or S- shaped curvature of the hairs" [J:4606]
is_a: MT:0000395 ! hair types

[Term]
id: MT:0000397
name: guard hair morphology
namespace: Trait.ontology
def: "anomalies of truncal hairs that contain two air cells in the medulla" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0000395 ! hair types

[Term]
id: MT:0000398
name: splitting of guard hairs
namespace: Trait.ontology
def: "intercellular splits and kinks within or along the hair shaft of the longest and straightest of the four hair types" [J:50844]
is_a: MT:0000397 ! guard hair morphology

[Term]
id: MT:0000399
name: curvature of guard hairs
namespace: Trait.ontology
def: "greater bending arch of the guard hairs" [J:47620]
is_a: MT:0000396 ! curvature of hairs
is_a: MT:0000397 ! guard hair morphology

[Term]
id: MT:0000400
name: awl hair morphology
namespace: Trait.ontology
def: "anomalies of truncal hairs that contain two or more air cells in the medulla" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0000395 ! hair types

[Term]
id: MT:0000401
name: curvature of awl hairs
namespace: Trait.ontology
def: "greater bending arch of the awl hairs" [J:47620]
is_a: MT:0000396 ! curvature of hairs
is_a: MT:0000400 ! awl hair morphology

[Term]
id: MT:0000402
name: zigzag hair morphology
namespace: Trait.ontology
def: "anomalies of truncal hairs that contain one air cell in the medulla" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0000395 ! hair types

[Term]
id: MT:0000403
name: curvature of zigzag hairs
namespace: Trait.ontology
def: "greater bending arch of the zigzag hairs" [J:47620]
is_a: MT:0000396 ! curvature of hairs
is_a: MT:0000402 ! zigzag hair morphology

[Term]
id: MT:0000405
name: auchene hair morphology
namespace: Trait.ontology
def: "anomalies of truncal hairs that contain two or more air cells in the medulla" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0000395 ! hair types

[Term]
id: MT:0000406
name: curvature of auchene hairs
namespace: Trait.ontology
def: "greater bending arch of the auchene hairs" [J:47620]
is_a: MT:0000396 ! curvature of hairs
is_a: MT:0000405 ! auchene hair morphology

[Term]
id: MT:0000407
name: duvet hair morphology
namespace: Trait.ontology
def: "anomalies of the fine under hair of the coat" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0000395 ! hair types

[Term]
id: MT:0000410
name: waved hair
namespace: Trait.ontology
def: "hair or fur having undulations or a sinusoidal shape" [J:47620]
synonym: "curly hair" EXACT []
synonym: "waved fur" EXACT []
synonym: "wavy hair" EXACT []
is_a: MT:0001510 ! coat appearance

[Term]
id: MT:0000411
name: shiny fur
namespace: Trait.ontology
def: "fur with a glossy or glistening appearance" [J:45065]
is_a: MT:0001510 ! coat appearance

[Term]
id: MT:0000413
name: phalanx number
namespace: Trait.ontology
def: "increased number of phalanges in any of the digits" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:13069]
is_a: MT:0005306 ! phalanx morphology

[Term]
id: MT:0000414
name: hair retention
namespace: Trait.ontology
def: "length of time that hair is maintained without noticable loss" [J:30772, J:33796, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "onset of hair loss" EXACT []
is_a: MT:0002073 ! hair growth

[Term]
id: MT:0000416
name: hair density
namespace: Trait.ontology
def: "number of body hair within a defined area" [J:46854]
synonym: "coat density" RELATED []
is_a: MT:0001510 ! coat appearance
is_a: MT:0002073 ! hair growth

[Term]
id: MT:0000417
name: hair length
namespace: Trait.ontology
def: "reduced average length of the hairs" [J:64948]
is_a: MT:0002073 ! hair growth

[Term]
id: MT:0000418
name: patchy hair
namespace: Trait.ontology
def: "uneven spots of hair growth on the body" [J:26975]
is_a: MT:0001510 ! coat appearance

[Term]
id: MT:0000419
name: rough hair
namespace: Trait.ontology
def: "greasy, matted appearance of the fur" [J:31155]
is_a: MT:0002074 ! hair texture

[Term]
id: MT:0000420
name: ruffled hair
namespace: Trait.ontology
def: "fuzzy, irregular appearance of the hair" [J:50844]
is_a: MT:0001510 ! coat appearance

[Term]
id: MT:0000421
name: mottled coat
namespace: Trait.ontology
def: "coat has spots, streaks, and/or blotches of a different color" [J:17194]
synonym: "mottled fur" EXACT []
is_a: MT:0005366 ! variegated coat color

[Term]
id: MT:0000422
name: onset of hair appearance
namespace: Trait.ontology
def: "time of the first appearance of the hair" [J:17792]
synonym: "delayed hair growth" EXACT []
is_a: MT:0002073 ! hair growth

[Term]
id: MT:0000423
name: onset of hair regrowth
namespace: Trait.ontology
def: "timing of initiation and synchrony of the hair growth cycle (anagen) after catagen phase " [J:61509]
is_a: MT:0002073 ! hair growth

[Term]
id: MT:0000424
name: hair growth rate
namespace: Trait.ontology
def: "slow growth of the hair, appears at normal time" [J:5476]
is_a: MT:0002073 ! hair growth

[Term]
id: MT:0000425
name: cilia retention
namespace: Trait.ontology
def: "ilength of time that eyelashes are maintained without noticable loss" [J:45400]
synonym: "loss of eyelashes" EXACT []
is_a: MT:0002073 ! hair growth

[Term]
id: MT:0000426
name: ectopic hair growth
namespace: Trait.ontology
def: "positional abnormality of hair " [J:24350]
synonym: "heterotopic hair growth" EXACT []
is_a: MT:0002073 ! hair growth

[Term]
id: MT:0000427
name: hair cycle
namespace: Trait.ontology
def: "aberrant growth or asynchronous timing of the hair growth " [J:65302]
is_a: MT:0002073 ! hair growth

[Term]
id: MT:0000428
name: craniofacial morphology
namespace: Trait.ontology
def: "anomalous structure or development of the face and/or cranium" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_pig
synonym: "craniofacial abnormalities" EXACT []
synonym: "craniofacial defects" EXACT []
is_a: MT:0005382 ! craniofacial trait

[Term]
id: MT:0000430
name: maxillary shelf morphology
namespace: Trait.ontology
alt_id: MT:0000112
def: "missing outgrowth of the maxilla; normally fuses with palatine shelf to form secondary palate" [J:17489, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "absent maxillary palatial process" EXACT []
synonym: "absent palatine process" EXACT []
is_a: MT:0000455 ! maxilla morphology

[Term]
id: MT:0000431
name: palatine shelf morphology
namespace: Trait.ontology
alt_id: MT:0000113
def: "missing outgrowth of the palatine bone; normally fuses with maxillary shelf to form secondary palate " [J:17489, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "absent horizontal plate" RELATED []
synonym: "absent palatine palatal process" EXACT []
is_a: MT:0005249 ! palatine bone morphology

[Term]
id: MT:0000432
name: head morphology
namespace: Trait.ontology
def: "anomalous structure or development of the portion of the body containing the brain and organs of sight, hearing, taste, and smell" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_pig
synonym: "abnormal head" EXACT []
synonym: "head abnormalities" EXACT []
is_a: MT:0000428 ! craniofacial morphology

[Term]
id: MT:0000436
name: head movements
namespace: Trait.ontology
alt_id: MT:0001390
def: "anomalous motion of the portion of the body containing the brain and organs of sight, hearing, taste, and smell " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal head movement" EXACT []
is_a: MT:0001388 ! stationary movement

[Term]
id: MT:0000437
name: taut facial appearance
namespace: Trait.ontology
def: "skin of face has appearance of being drawn or pulled tightly" [J:61768]
is_a: MT:0003743 ! facial morphology

[Term]
id: MT:0000438
name: skull morphology
namespace: Trait.ontology
def: "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal cranium" EXACT []
synonym: "abnormal skull" EXACT []
synonym: "cranial abnormalities" EXACT []
synonym: "skull abnormalities" EXACT []
is_a: MT:0002116 ! craniofacial bone morphology

[Term]
id: MT:0000443
name: snout morphology
namespace: Trait.ontology
def: "anomalous structure or development of the anterior facial part of the muzzle" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal snout" EXACT []
synonym: "snout abnormalities" EXACT []
is_a: MT:0003743 ! facial morphology

[Term]
id: MT:0000444
name: snout shape
namespace: Trait.ontology
def: "morphological anomalies of the anterior facial part of the muzzle" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "snout shape abnormalities" EXACT []
is_a: MT:0000443 ! snout morphology

[Term]
id: MT:0000446
name: snout length
namespace: Trait.ontology
def: "the anterior facial part of the muzzle having a length greater than seen in controls" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0000444 ! snout shape

[Term]
id: MT:0000447
name: flattened snout
namespace: Trait.ontology
def: "a snout flattened laterally along the whole length without the appearance of distinctive curvature" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000444 ! snout shape

[Term]
id: MT:0000448
name: pointed snout
namespace: Trait.ontology
def: "nose tapers to a small tip, sharper angle than wild type " [J:18378]
is_a: MT:0000444 ! snout shape

[Term]
id: MT:0000449
name: nasal bridge width
namespace: Trait.ontology
def: "distance across the upper part of the ridge of the nose" [J:53370]
is_a: MT:0000444 ! snout shape

[Term]
id: MT:0000451
name: scaly muzzle
namespace: Trait.ontology
def: "muzzle covered with shedding scales or flakes" [J:56641]
is_a: MT:0000443 ! snout morphology

[Term]
id: MT:0000452
name: mouth morphology
namespace: Trait.ontology
def: "anomalous structure or development of the oral cavity" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal mouth" EXACT []
synonym: "mouth abnormalities" EXACT []
is_a: MT:0003744 ! orofacial morphology

[Term]
id: MT:0000454
name: jaw morphology
namespace: Trait.ontology
def: "malformation of the bony framework of the mouth where the teeth are held" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal jaw" EXACT []
synonym: "jaw abnormalities" EXACT []
is_a: MT:0000438 ! skull morphology

[Term]
id: MT:0000455
name: maxilla morphology
namespace: Trait.ontology
alt_id: MT:0000089
def: "malformation of the upper bony framework of the mouth where the superior teeth are held" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal maxilla" EXACT []
synonym: "Abnormal Upper Jaw" EXACT []
is_a: MT:0000454 ! jaw morphology
is_a: MT:0005274 ! viscerocranium morphology
is_a: MT:0005552 ! orbital bone morphology

[Term]
id: MT:0000458
name: mandible morphology
namespace: Trait.ontology
alt_id: MT:0000086
def: "malformation of the lower bony framework of the mouth where the inferior teeth are held" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal lower jaw" EXACT []
synonym: "abnormal mandible" EXACT []
is_a: MT:0000454 ! jaw morphology
is_a: MT:0005274 ! viscerocranium morphology

[Term]
id: MT:0000459
name: presacral vertebrae
namespace: Trait.ontology
def: "malformation or absence of the vertebrae anterior to the sacrum" [J:13069]
is_a: MT:0000137 ! vertebrae morphology

[Term]
id: MT:0000461
name: number of presacral vertebrae
namespace: Trait.ontology
def: "reduced number of the vertebrae anterior to the sacrum" [J:13069]
synonym: "reduced number of presacral vertebrae" EXACT []
is_a: MT:0000459 ! presacral vertebrae
relationship: part_of MT:0000138 ! vertebrae number

[Term]
id: MT:0000462
name: digestive system morphology
namespace: Trait.ontology
alt_id: MT:0000463
alt_id: MT:0002141
def: "anomalous structure of the system dedicated to the mechanical, chemical, and enzymatic processing of food" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
subset: slim_pig
synonym: "digestive system abnormalities" EXACT []
synonym: "digestive system defects" EXACT []
synonym: "digestive system: dysmorphology" EXACT []
xref: MGI:2173601
is_a: MT:0005381 ! digestive/alimentary trait

[Term]
id: MT:0000465
name: gastrointestinal hemorrhage
namespace: Trait.ontology
def: "bleeding in the stomach and/or the intestines" [J:60896, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8, tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "gastroenteric bleeding" EXACT []
synonym: "gastroenteric hemorrhage" EXACT []
synonym: "gastrointestinal bleeding" EXACT []
is_a: MT:0001663 ! digestive system physiology

[Term]
id: MT:0000466
name: esophageal epithelium cell number
namespace: Trait.ontology
def: "increased cell number in the epithelial layer of the esophagus" [J:47225]
synonym: "hyperplasia of the esophageal epithelium" EXACT []
is_a: MT:0000468 ! esophageal epithelium morphology

[Term]
id: MT:0000467
name: esophagus morphology
namespace: Trait.ontology
def: "malformation of the part of the digestive canal through which food passes from the pharynx to the stomach" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8, tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "abnormal esophagus" EXACT []
synonym: "esophagus abnormalities" EXACT []
is_a: MT:0000462 ! digestive system morphology

[Term]
id: MT:0000468
name: esophageal epithelium morphology
namespace: Trait.ontology
def: "malformation of the epithelial layer of the esophagus" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8, tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "abnormal esophageal epithelium" EXACT []
synonym: "esophageal epithelium abnormalities" EXACT []
is_a: MT:0000467 ! esophagus morphology

[Term]
id: MT:0000469
name: esophageal squamous epithelium morphology
namespace: Trait.ontology
def: "malformation of the scaly epithelial layer of the esophagus" [J:54637, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8, tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "abnormal esophageal squamous epithelium" EXACT []
is_a: MT:0000468 ! esophageal epithelium morphology

[Term]
id: MT:0000470
name: stomach morphology
namespace: Trait.ontology
def: "malformation of the sac-like structure of the digestive canal between the esophagus and the small intestine" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal stomach" EXACT []
synonym: "stomach abnormalities" EXACT []
is_a: MT:0000462 ! digestive system morphology

[Term]
id: MT:0000471
name: stomach epithelium morphology
namespace: Trait.ontology
def: "malformation of the epithelial layer of the stomach " [tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "abnormal stomach epithelium" EXACT []
synonym: "stomach epithelium abnormalities" EXACT []
is_a: MT:0000470 ! stomach morphology

[Term]
id: MT:0000472
name: stomach squamous epithelium morphology
namespace: Trait.ontology
def: "malformation of the scaly epithelial layer of the stomach" [J:54637, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8, tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "abnormal stomach squamous epithelium" EXACT []
is_a: MT:0000471 ! stomach epithelium morphology

[Term]
id: MT:0000473
name: stomach glandular epithelium morphology
namespace: Trait.ontology
def: "malformation of the gland-containing epithelial layer of the stomach" [J:54637, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8, tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "abnormal stomach glandular epithelium" EXACT []
is_a: MT:0000471 ! stomach epithelium morphology

[Term]
id: MT:0000474
name: foregut morphology
namespace: Trait.ontology
def: "malformed cephalic portion of the primitive digestive tube of the embryo" [J:35802]
synonym: "abnormal foregut" EXACT []
synonym: "foregut abnormalities" EXACT []
is_a: MT:0003119 ! digestive system development

[Term]
id: MT:0000476
name: cochlear nerve fiber response
namespace: Trait.ontology
def: "the electrophysiological recordings from a single or several auditory nerve fiber(s" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "auditory nerve fiber response" RELATED []
is_a: MT:0000365 ! hearing electrophysiology
is_a: MT:0000483 ! sensorineural hearing function
is_a: MT:0003477 ! nerve fiber response

[Term]
id: MT:0000477
name: intestine morphology
namespace: Trait.ontology
alt_id: MT:0000475
def: "malformation of the digestive tube passing from the stomach to the anus" [J:48968]
subset: slim_pig
synonym: "abnormal bowel wall" EXACT []
synonym: "abnormal intestine" EXACT []
synonym: "bowel wall abnormalities" EXACT []
synonym: "intestinal abnormalities" EXACT []
is_a: MT:0000462 ! digestive system morphology

[Term]
id: MT:0000478
name: intestine development
namespace: Trait.ontology
def: "slowed progression to a structurally mature intestine" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "developmental retardation of the intestine" EXACT []
is_a: MT:0000477 ! intestine morphology
is_a: MT:0003119 ! digestive system development

[Term]
id: MT:0000479
name: intestinal cell morphology
namespace: Trait.ontology
def: "anomalous structure or development of the cells comprising the intestine" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal enterocyte" EXACT []
synonym: "intestinal cell abnormalities" EXACT []
is_a: MT:0000477 ! intestine morphology

[Term]
id: MT:0000481
name: intestinal cell number
namespace: Trait.ontology
def: "deviation from the normal numbers of enterocytes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal enterocyte number" EXACT []
is_a: MT:0000479 ! intestinal cell morphology

[Term]
id: MT:0000482
name: fibula length
namespace: Trait.ontology
def: "increased length of the lateral and smaller of bone of the lower leg" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
is_a: MT:0002187 ! fibula morphology

[Term]
id: MT:0000483
name: sensorineural hearing function
namespace: Trait.ontology
def: "form of hearing due to processes occuring in the auditory division of cranial nerve VIII or the inner ear" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001963 ! hearing

[Term]
id: MT:0000484
name: pulmonary artery morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the artery that conveys unaerated blood to the lungs" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
xref: MP:0000484
is_a: MT:0002191 ! artery morphology

[Term]
id: MT:0000485
name: otoacoustic response
namespace: Trait.ontology
def: "the acoustic energy produced by the cochlea in the presence or absence of sound stimulation" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "otoacoustic emissions" RELATED []
is_a: MT:0002104 ! hearing physiology

[Term]
id: MT:0000486
name: pulmonary trunk integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the region of the pulmonary artery that arises from the right ventricle to the division of the right and left pulmonary artery" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
relationship: part_of MT:0007054 ! pulmonary artery integrity

[Term]
id: MT:0000488
name: intestinal epithelium morphology
namespace: Trait.ontology
def: "anomalous structure or development of the cellular avascular layer of the digestive tube passing from the stomach to the anus" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal intestinal epithelium" EXACT []
synonym: "intestinal epithelium abnormalities" EXACT []
is_a: MT:0000477 ! intestine morphology

[Term]
id: MT:0000489
name: large intestine morphology
namespace: Trait.ontology
def: "structural or developmental anomalies of the intestinum crassum " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal large intestine" EXACT []
synonym: "large intestine abnormalities" EXACT []
is_a: MT:0000477 ! intestine morphology

[Term]
id: MT:0000490
name: crypts of Lieberkuhn morphology
namespace: Trait.ontology
def: "malformation or defects in the tubular intestinal glands found in the mucosal membranes" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal crypts of Lieberkuhn" EXACT []
synonym: "abnormal intestinal gland morphology" EXACT []
synonym: "abnormal intestinal glands" EXACT []
is_a: MT:0000489 ! large intestine morphology
is_a: MT:0000496 ! small intestine morphology
is_a: MT:0000511 ! intestinal mucosa morphology
is_a: MT:0002163 ! gland morphology

[Term]
id: MT:0000491
name: crypt abscesses
namespace: Trait.ontology
def: "an exudate collection associated with inflammation in the crypts of Lieberkuhn of the intestinal mucosa; often associated with ulcerative colitis" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000490 ! crypts of Lieberkuhn morphology

[Term]
id: MT:0000492
name: rectum morphology
namespace: Trait.ontology
def: "structural aberration in the terminal portion of the intestinal tube adjacent to the anus" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal rectum" EXACT []
synonym: "rectum abnormalities" EXACT []
is_a: MT:0000489 ! large intestine morphology

[Term]
id: MT:0000493
name: rectal prolapse
namespace: Trait.ontology
def: "downward movement and external appearance of the rectum through the anus" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8, tc:Teresa Chu_Mouse Genome Informatics Curator]
is_a: MT:0000492 ! rectum morphology

[Term]
id: MT:0000494
name: cecum morphology
namespace: Trait.ontology
def: "malformation of the large sac at the ileum and large intestine junction" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal cecum" EXACT []
synonym: "cecum abnormalities" EXACT []
is_a: MT:0000489 ! large intestine morphology

[Term]
id: MT:0000495
name: colon morphology
namespace: Trait.ontology
def: "malformation of the portion of the large intestine between the cecum and the rectum" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal colon" EXACT []
synonym: "colon abnormalities" EXACT []
is_a: MT:0000489 ! large intestine morphology

[Term]
id: MT:0000496
name: small intestine morphology
namespace: Trait.ontology
def: "structural or developmental anomalies of the intestinum tenue" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_pig
synonym: "abnormal small intestine" EXACT []
synonym: "small intestine abnormalities" EXACT []
is_a: MT:0000477 ! intestine morphology

[Term]
id: MT:0000497
name: small intestine placement
namespace: Trait.ontology
def: "different location or arrangement of the small intestinal tract" [J:40203]
is_a: MT:0000496 ! small intestine morphology
is_a: MT:0003283 ! digestive organ placement

[Term]
id: MT:0000500
name: small intestinal prolapse
namespace: Trait.ontology
def: "the sinking down of the intestinum tenue " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000496 ! small intestine morphology

[Term]
id: MT:0000501
name: digestive secretion
namespace: Trait.ontology
def: "malfunction of the production and/or release of a physiologically active substance (usually but not exclusively in liquid form) from a cell or a gland of the digestive system" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8, tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "abnormal secretion" EXACT []
is_a: MT:0001664 ! digestion

[Term]
id: MT:0000502
name: distortion product otoacoustic emission
namespace: Trait.ontology
def: "production of sound by the cochlea in response to stimulation with 2 simultaneous tones of different frequencies; this measurement is particularly useful in assessing the functional state of OHCs" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "DPOAE" RELATED []
is_a: MT:0000485 ! otoacoustic response

[Term]
id: MT:0000508
name: right-sided isomerism
namespace: Trait.ontology
def: "the relative symmetry of the organs of the thorax and abdomen as indicated by both atria displaying the morphology of the right atrium" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:58530]
is_a: MT:0002089 ! postnatal growth/weight/body size

[Term]
id: MT:0000509
name: digestive mucosecretion
namespace: Trait.ontology
def: "missing the production and/or release of a physiologically active substance (usually but not exclusively in liquid form) from the mucous membrane of the digestive system" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8, tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "absence of digestive mucosecretion" EXACT []
synonym: "absence of mucosecretion" EXACT []
synonym: "loss of mucosecretion" EXACT []
is_a: MT:0000501 ! digestive secretion

[Term]
id: MT:0000510
name: remittent intestinal hemorrhage
namespace: Trait.ontology
def: "loss of blood from the intestines that is characterized by temporary periods of abatement" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "remittent intestinal bleeding" EXACT []
is_a: MT:0000465 ! gastrointestinal hemorrhage

[Term]
id: MT:0000511
name: intestinal mucosa morphology
namespace: Trait.ontology
def: "structural or developmental anomalies of the mucous lining of the intestine; this consists of epithelium, lamina propria, and a layer of smooth muscle cells" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal intestinal mucosa" EXACT []
synonym: "abnormal mucosa of the intestine" EXACT []
synonym: "intestinal mucosa abnormalities" EXACT []
is_a: MT:0000488 ! intestinal epithelium morphology

[Term]
id: MT:0000512
name: intestinal ulcer
namespace: Trait.ontology
def: "lesions in the mucous lining of the intestine" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "intestinal ulcers" EXACT []
synonym: "mucosal ulceration of the intestine" EXACT []
is_a: MT:0000511 ! intestinal mucosa morphology
is_a: MT:0003300 ! gastrointestinal ulcer

[Term]
id: MT:0000513
name: susceptibility to hearing loss
namespace: Trait.ontology
def: "the sensitivity to loss of hearing related to age or environmental factors" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001963 ! hearing

[Term]
id: MT:0000516
name: urinary system morphology
namespace: Trait.ontology
alt_id: MT:0000517
def: "structural or developmental anomaly of any of the organs involved in the production or excretion of urine " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal urinary organs" EXACT []
synonym: "excretory system defects" EXACT []
synonym: "urinary organ abnormalities" EXACT []
is_a: MT:0005367 ! renal/urinary system trait

[Term]
id: MT:0000519
name: hydronephrosis
namespace: Trait.ontology
def: "dilation of the pelvis and calices of one or both kidneys" [J:56641]
synonym: "renal pelvic dilation" EXACT []
is_a: MT:0004194 ! kidney pelvis morphology

[Term]
id: MT:0000521
name: kidney cortex
namespace: Trait.ontology
def: "anomalous structure or development of the outer area of the kidney, which contains the glomerular capillaries and the capsula glomeruli that enclose it " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "kidney cortex abnormalities" EXACT []
is_a: MT:0002135 ! kidney morphology

[Term]
id: MT:0000522
name: cysts in kidney cortex
namespace: Trait.ontology
def: "abnormal membranous sacs appearing in the renal lobules, tubules and glomeruli" [J:50844]
is_a: MT:0000521 ! kidney cortex
is_a: MT:0003675 ! kidney cysts

[Term]
id: MT:0000523
name: cortical glomerulopathies
namespace: Trait.ontology
def: "any disease of the capillary plexus in the kidney cortex" [J:63229, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005325 ! glomerulus morphology

[Term]
id: MT:0000524
name: renal tubule number
namespace: Trait.ontology
def: "fewer loops of Henle and collecting ducts" [J:40203]
synonym: "reduced number of renal tubules" EXACT []
is_a: MT:0002703 ! renal tubule morphology

[Term]
id: MT:0000525
name: renal tubular acidosis
namespace: Trait.ontology
def: "a clinical syndrome characterized by the inability to acidify urine" [J:19268, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002136 ! kidney physiology

[Term]
id: MT:0000526
name: inner medullary pyramid size
namespace: Trait.ontology
def: "reduced size of pyramidal masses; contain part of the secreting tubules and collecting tubules" [J:40203, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0004192 ! kidney pyramid morphology

[Term]
id: MT:0000527
name: kidney development
namespace: Trait.ontology
def: "anomalous differentiation of the paired organs responsible for urine secretion" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal renal development" EXACT []
synonym: "kidney development abnormalities" EXACT []
is_a: MT:0002135 ! kidney morphology
is_a: MT:0003942 ! urinary system development

[Term]
id: MT:0000528
name: onset of kidney development
namespace: Trait.ontology
alt_id: MT:0000529
def: "late onset of the induction and/or differentiation of the kidney" [J:18048]
synonym: "delayed renal development" EXACT []
synonym: "developmental retardation of kidney" EXACT []
is_a: MT:0000527 ! kidney development

[Term]
id: MT:0000530
name: kidney blood vessel morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the the blood vessel network of the organ of excretion" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "kidney vascular morphology" RELATED []
synonym: "kidney vasculature" EXACT []
synonym: "renal vasculature" RELATED []
xref: MP:0000530
is_a: MT:0001614 ! blood vessel morphology
is_a: MT:0002135 ! kidney morphology

[Term]
id: MT:0000531
name: right pulmonary isomerism
namespace: Trait.ontology
def: "bilaterally symmetric right lung pattern (or altered asymmetric patterning of the lung)" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:58530]
is_a: MT:0000508 ! right-sided isomerism
is_a: MT:0001175 ! lung morphology

[Term]
id: MT:0000532
name: kidney blood vessel patency
namespace: Trait.ontology
alt_id: MT:0000257
def: "any measurable characteristic pertaining to the openness of  the blood vessels of the organ of secretion" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "kidney vascular patency" EXACT []
synonym: "patency of the renal vasculature" RELATED []
is_a: MT:0005412 ! blood vessel patency
relationship: part_of MT:0007055 ! kidney blood vessel integrity

[Term]
id: MT:0000533
name: kidney hemorrhage
namespace: Trait.ontology
def: "bleeding in the organ of excretion" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8, tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "kidney bleeding" EXACT []
is_a: MT:0002136 ! kidney physiology

[Term]
id: MT:0000534
name: ureter morphology
namespace: Trait.ontology
def: "anomalous structure of the tube that conducts the urine from the renal pelvis to the bladder" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "ureter abnormalities" EXACT []
is_a: MT:0000516 ! urinary system morphology

[Term]
id: MT:0000535
name: ureter luminal epithelial cell number
namespace: Trait.ontology
def: "increased cell number in the luminal epithelium of the tube that conducts the urine from the renal pelvis to the bladder" [J:56641]
synonym: "hyperplasia of the luminal epithelium of ureter" EXACT []
is_a: MT:0000534 ! ureter morphology

[Term]
id: MT:0000536
name: hydroureter
namespace: Trait.ontology
def: "distention of the ureter with urine, due to blockage from any cause" [cml:Cathleen M. Lutz_Mouse Genome Informatics Curator, J:13044, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000534 ! ureter morphology

[Term]
id: MT:0000537
name: urethra morphology
namespace: Trait.ontology
def: "anomalous structure of the canal leading from the bladder, discharging the urine externally" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "urethra abnormalities" EXACT []
is_a: MT:0000516 ! urinary system morphology

[Term]
id: MT:0000538
name: urinary bladder morphology
namespace: Trait.ontology
def: "malformation of the inflatable musculomembranous bag for holding urine" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal urinary bladder" EXACT []
is_a: MT:0000516 ! urinary system morphology

[Term]
id: MT:0000539
name: urinary bladder size
namespace: Trait.ontology
def: "stretched musculomembranous bag for holding urine" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "urinary bladder distension" EXACT []
is_a: MT:0000538 ! urinary bladder morphology

[Term]
id: MT:0000540
name: urinary bladder epithelium morphology
namespace: Trait.ontology
def: "malformation of the epithelial layer of the urinary bladder" [tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "urinary bladder epithelium abnormalities" EXACT []
is_a: MT:0000538 ! urinary bladder morphology

[Term]
id: MT:0000541
name: urinary bladder transitional epithelium morphology
namespace: Trait.ontology
def: "malformation of the transitional epithelial layer of the urinary bladder" [tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "urinary bladder transitional epithelium abnormalities" EXACT []
is_a: MT:0000540 ! urinary bladder epithelium morphology

[Term]
id: MT:0000542
name: left-sided isomerism
namespace: Trait.ontology
def: "the relative symmetry of the organs of the thorax and abdomen as indicated by both atria displaying the morphology of the left atrium" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0002089 ! postnatal growth/weight/body size

[Term]
id: MT:0000544
name: urinary bladder transitional epithelium thickness
namespace: Trait.ontology
def: "decrease in the thickness of the transitional epithelial layer of the urinary bladder" [J:54637, tc:Teresa Chu_Mouse Genome Informatics Curator]
is_a: MT:0000541 ! urinary bladder transitional epithelium morphology

[Term]
id: MT:0000545
name: limbs/digits/tail morphology
namespace: Trait.ontology
def: "morphological or developmental anomaly of the digits, autopod, limbs, or tail" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "abnormal extremities" EXACT []
synonym: "abnormal extremity morphology" EXACT []
synonym: "extremities abnormalities" EXACT []
synonym: "extremities defects" EXACT []
is_a: MT:0005371 ! limbs/digits/tail trait

[Term]
id: MT:0000548
name: limb length
namespace: Trait.ontology
def: "average length of the extremities" [tc:Teresa Chu_Mouse Genome Informatics Curator]
subset: slim_pig
synonym: "leg length" RELATED []
is_a: MT:0002109 ! limb morphology

[Term]
id: MT:0000550
name: forelimb morphology
namespace: Trait.ontology
def: "Any measurable or observable characteristic related to the shape, structure, color or pattern of the anterior extremeties" [tc:Teresa Chu_Mouse Genome Informatics Curator]
subset: slim_chkn
subset: slim_pig
synonym: "forelimb abnormalities" EXACT []
is_a: MT:0002109 ! limb morphology

[Term]
id: MT:0000552
name: radius morphology
namespace: Trait.ontology
def: "malformation of the short bone of the lateral forearm" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal radius" EXACT []
is_a: MT:0003723 ! long bone morphology

[Term]
id: MT:0000554
name: carpal bone morphology
namespace: Trait.ontology
def: "malformation of the nine nodular bones of the joint between the forelimb bones and the front paws consisting of the scapholunar, triangular, greater multiangular, lesser multiangular, capitate, hamate, centrale and the sesamoids" [Anatomy of the Rat:Greene EC_Hafner Publishing Co_1935, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
comment: Note that the bony structure of the human carpals are different.
synonym: "abnormal carpal bone" EXACT []
synonym: "abnormal carpus" EXACT []
synonym: "abnormal wrist" EXACT []
is_a: MT:0002115 ! skeleton extremities morphology

[Term]
id: MT:0000556
name: hindlimb morphology
namespace: Trait.ontology
def: "Any measurable or observable characteristic related to the shape, structure, color or pattern of the posterior extremeties" [tc:Teresa Chu_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "hindlimb abnormalities" EXACT []
is_a: MT:0002109 ! limb morphology

[Term]
id: MT:0000558
name: tibia morphology
namespace: Trait.ontology
def: "structural anomaly of the medial and larger of the two bones of the lower leg" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
synonym: "abnormal tibia" EXACT []
is_a: MT:0003723 ! long bone morphology

[Term]
id: MT:0000559
name: femur morphology
namespace: Trait.ontology
def: "structural anomaly of the long bone of the thigh" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_pig
synonym: "abnormal femur" EXACT []
is_a: MT:0003723 ! long bone morphology

[Term]
id: MT:0000561
name: adactyly
namespace: Trait.ontology
def: "missing all digits; usually referred to as a congenital condition" [J:54637, tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "absence of digits" EXACT []
is_a: MT:0002110 ! digit morphology

[Term]
id: MT:0000562
name: polydactyly
namespace: Trait.ontology
def: "greater than 5 digits on one or more autopods" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002110 ! digit morphology

[Term]
id: MT:0000564
name: syndactyly
namespace: Trait.ontology
def: "any degree of webbing or fusion of the digits, may involve only soft tissues or also can include bone" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002110 ! digit morphology

[Term]
id: MT:0000565
name: oligodactyly
namespace: Trait.ontology
alt_id: MT:0000563
def: "congenital condition in which some digits or parts of digits are missing" [J:53370, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "hypodactyly" EXACT []
is_a: MT:0002110 ! digit morphology

[Term]
id: MT:0000566
name: synostosis
namespace: Trait.ontology
def: "osseous union of two bones that are not normally connected" [J:13049]
is_a: MT:0002110 ! digit morphology

[Term]
id: MT:0000567
name: truncation of digits
namespace: Trait.ontology
def: "absence of the most proximal regions of toes" [J:19212]
is_a: MT:0002110 ! digit morphology

[Term]
id: MT:0000568
name: ectopic digits
namespace: Trait.ontology
def: "positional abnormality of a digit" [J:50311]
synonym: "heterotopic digits" EXACT []
is_a: MT:0002110 ! digit morphology

[Term]
id: MT:0000569
name: digit pigmentation
namespace: Trait.ontology
alt_id: MT:0000570
def: "anomalous coloration of the fingers or toes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "altered digit pigmentation" EXACT []
synonym: "white hind toes" EXACT []
is_a: MT:0001186 ! pigmentation trait
is_a: MT:0002110 ! digit morphology

[Term]
id: MT:0000571
name: interdigital webbing
namespace: Trait.ontology
def: "fold of skin, or web, between the toes that is not normally present" [J:49840, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002110 ! digit morphology

[Term]
id: MT:0000572
name: autopod morphology
namespace: Trait.ontology
def: "malformation of the distal elements of the developing limb of vertebrates that will give rise to the pedal or prehensile appendages (e.g. hand, foot, paw, phalanges and/or digits)" [PMID:12560810]
is_a: MT:0006279 ! limb development

[Term]
id: MT:0000573
name: hind paw size
namespace: Trait.ontology
def: "larger than average size of the rear feet" [J:51296]
is_a: MT:0004271 ! paw/hand/foot/hoof morphology

[Term]
id: MT:0000574
name: foot pad morphology
namespace: Trait.ontology
def: "anomalous structure of the body of fat on the foot" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal foot pads" EXACT []
is_a: MT:0004271 ! paw/hand/foot/hoof morphology

[Term]
id: MT:0000575
name: foot pad pigmentation
namespace: Trait.ontology
def: "darker color of the foot pads due to excess pigment" [cml:Cathleen M. Lutz_Mouse Genome Informatics Curator]
is_a: MT:0000574 ! foot pad morphology
is_a: MT:0002095 ! skin pigmentation

[Term]
id: MT:0000576
name: clubfoot
namespace: Trait.ontology
def: "congenital deformation of the feet; foot is plantarflexed, inverted and adducted" [J:61295, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "club foot" EXACT []
synonym: "clubbed feet" EXACT []
is_a: MT:0004271 ! paw/hand/foot/hoof morphology

[Term]
id: MT:0000578
name: ulcerated paws
namespace: Trait.ontology
def: "inflammatory, often suppurating lesions on the paws; often become necrotic" [J:17194]
is_a: MT:0004271 ! paw/hand/foot/hoof morphology

[Term]
id: MT:0000579
name: nail morphology
namespace: Trait.ontology
def: "structural or developmental anomaly of any of the thin, horny, translucent plates covering the dorsal surface of the distal end of each terminal phalanx of the digits" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal nail" EXACT []
synonym: "nail abnormalities" EXACT []
is_a: MT:0005393 ! skin/coat/nails/feathers trait

[Term]
id: MT:0000580
name: nail shape
namespace: Trait.ontology
def: "atypical shape or size of the nails" [J:45400]
is_a: MT:0000579 ! nail morphology

[Term]
id: MT:0000581
name: ventral nails/ hair
namespace: Trait.ontology
def: "appearance of nails and hair on the ventral side of the paw" [J:50311]
is_a: MT:0000579 ! nail morphology

[Term]
id: MT:0000582
name: toenail hyperkeratosis
namespace: Trait.ontology
def: "keratin extensions from the toenails" [J:62478]
is_a: MT:0000579 ! nail morphology

[Term]
id: MT:0000583
name: toenail length
namespace: Trait.ontology
def: "increased length of the toenails" [J:65045]
is_a: MT:0000579 ! nail morphology

[Term]
id: MT:0000588
name: tail diameter
namespace: Trait.ontology
def: "length of a straight line segment passing through a specified cross-section of the tail " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0003456 ! tail size

[Term]
id: MT:0000593
name: susceptibility to noise-induced hearing loss
namespace: Trait.ontology
def: "sensitivity to reduction in hearing following exposure to acute noise that is injurious to the cochlea" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000513 ! susceptibility to hearing loss

[Term]
id: MT:0000596
name: liver development
namespace: Trait.ontology
def: "anomalous differentiation of the liver" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0000598 ! liver morphology
is_a: MT:0003943 ! liver/biliary system development

[Term]
id: MT:0000597
name: onset of hepatic development
namespace: Trait.ontology
def: "late onset of the induction and/or differentiation of the liver" [J:18048]
is_a: MT:0000596 ! liver development

[Term]
id: MT:0000598
name: liver morphology
namespace: Trait.ontology
alt_id: MT:0000595
def: "malformation or absence of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:23170, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
subset: slim_pig
synonym: "abnormal liver" EXACT []
synonym: "Liver" EXACT []
is_a: MT:0002138 ! liver/biliary system morphology

[Term]
id: MT:0000599
name: liver size
namespace: Trait.ontology
def: "larger than average size of the liver" [J:65146]
synonym: "hepatomegaly" EXACT []
is_a: MT:0000598 ! liver morphology

[Term]
id: MT:0000602
name: sinusoidal space size
namespace: Trait.ontology
def: "larger than normal sized cavities in the liver " [J:23170]
is_a: MT:0000598 ! liver morphology

[Term]
id: MT:0000603
name: liver color
namespace: Trait.ontology
def: "liver lacking normal coloration, often refers to bloodless condition" [J:18048]
is_a: MT:0000598 ! liver morphology

[Term]
id: MT:0000604
name: amyloidosis
namespace: Trait.ontology
alt_id: MT:0000695
def: "an accumulation of extracellular amyloid in tissues of the body" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "amyloidosis" EXACT []
is_a: MT:0005395 ! other trait

[Term]
id: MT:0000606
name: hepatocyte number
namespace: Trait.ontology
def: "fewer than normal number of parenchymal liver cells" [J:23170]
synonym: "reduced hepatocyte cell number" EXACT []
is_a: MT:0000607 ! hepatocyte morphology

[Term]
id: MT:0000607
name: hepatocyte morphology
namespace: Trait.ontology
alt_id: MT:0000605
alt_id: MT:0002821
def: "malformation of the main structural component of the liver; these are specialized epithelial cells normally organize into interconnected plates called lobules" [J:23170, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal hepatocyte" EXACT []
synonym: "abnormal hepatocytes" EXACT []
synonym: "abnormal liver cells" EXACT []
is_a: MT:0000598 ! liver morphology

[Term]
id: MT:0000608
name: dissociated hepatocytes
namespace: Trait.ontology
def: "disorganization of cohesive hepatocyte structure" [J:23170]
synonym: "dissociation of liver parenchymal cells" EXACT []
is_a: MT:0000607 ! hepatocyte morphology

[Term]
id: MT:0000609
name: liver physiology
namespace: Trait.ontology
def: "aberrant function of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal liver function" EXACT []
is_a: MT:0002139 ! liver/biliary system physiology

[Term]
id: MT:0000610
name: cholestasis
namespace: Trait.ontology
def: "impairment of bile flow due to obstruction in small bile ducts (intrahepatic cholestasis) or obstruction in large bile ducts (extrahepatic cholestasis)" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "bile duct obstruction" EXACT []
synonym: "bile stasis" EXACT []
synonym: "biliary stasis" EXACT []
is_a: MT:0000609 ! liver physiology

[Term]
id: MT:0000611
name: jaundice
namespace: Trait.ontology
def: "clinical manifestation of hyperbilirubinemia, with deposition of bile pigments in the skin, resulting in yellowish staining of the skin and mucous membranes" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0000609 ! liver physiology

[Term]
id: MT:0000612
name: susceptibility to age-related hearing loss
namespace: Trait.ontology
def: "sensitivity to reduction in hearing associated with increased age" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000513 ! susceptibility to hearing loss

[Term]
id: MT:0000613
name: salivary gland morphology
namespace: Trait.ontology
def: "malformed saliva-secreting glands of the oral cavity" [J:63764, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal salivary glands" EXACT []
is_a: MT:0000462 ! digestive system morphology
is_a: MT:0002163 ! gland morphology

[Term]
id: MT:0000615
name: palatine gland morphology
namespace: Trait.ontology
def: "malformed salivary gland of the hard palate" [J:64981, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal palatine gland" EXACT []
is_a: MT:0003791 ! minor salivary gland morphology

[Term]
id: MT:0000616
name: palatine gland ductal branching morphology
namespace: Trait.ontology
def: "fewer branches and distal tips of the vesicles of the palatine gland" [J:64981]
is_a: MT:0000615 ! palatine gland morphology
is_a: MT:0000620 ! salivary duct morphology

[Term]
id: MT:0000617
name: number of salivary gland mucosal cells
namespace: Trait.ontology
def: "greater than normal number of cells that form mucus in the salivary glands" [J:64981]
is_a: MT:0000615 ! palatine gland morphology

[Term]
id: MT:0000619
name: salivary gland epithelial cell morphology
namespace: Trait.ontology
def: "increased cell number in the epithelium of the salivary gland" [J:63764, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000613 ! salivary gland morphology

[Term]
id: MT:0000620
name: salivary duct morphology
namespace: Trait.ontology
def: "reduced diameter of the tubular canals that carry saliva" [J:63764, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000613 ! salivary gland morphology

[Term]
id: MT:0000621
name: salivary adenocarcinoma
namespace: Trait.ontology
alt_id: MT:0002040
def: "malignant neoplasm of the secreting cells of the salivary gland" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "acinar carcinoma" EXACT []
synonym: "acinic cell adenocarcinoma" EXACT []
synonym: "acinic cell carcinoma" EXACT []
synonym: "Salivary Adenocarcinomas" EXACT []
is_a: MT:0002038 ! carcinoma

[Term]
id: MT:0000623
name: salivation
namespace: Trait.ontology
def: "decrease flow, secretion, or amount of saliva" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "sialoschesis" EXACT []
is_a: MT:0005310 ! salivary gland physiology

[Term]
id: MT:0000624
name: xerostomia
namespace: Trait.ontology
def: "dryness of the mouth resulting from reduced salivary secretion" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000623 ! salivation
is_a: MT:0003745 ! mucosal lining of the mouth

[Term]
id: MT:0000627
name: mammary gland morphology
namespace: Trait.ontology
def: "malformation of the milk-secreting gland that lies within the breast; usually rudimentary in males" [J:70183]
subset: slim_cattle
subset: slim_pig
synonym: "abnormal mammary glands" EXACT []
is_a: MT:0001119 ! female reproductive anatomy
is_a: MT:0002163 ! gland morphology

[Term]
id: MT:0000628
name: mammary gland development
namespace: Trait.ontology
alt_id: MT:0003428
def: "aberration in the differentiation of the mammary gland during early embryogenesis or during sexual maturity" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal mammary development" EXACT []
is_a: MT:0000627 ! mammary gland morphology
is_a: MT:0003936 ! reproductive system development

[Term]
id: MT:0000631
name: neuroendocrine gland morphology
namespace: Trait.ontology
def: "anomalous structure of any of the organized aggregations of cells that function as secretory or excretory organs and that release hormones in response to neural stimuli" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal neuroendocrine glands" EXACT []
is_a: MT:0002163 ! gland morphology

[Term]
id: MT:0000632
name: pineal gland morphology
namespace: Trait.ontology
def: "anomalous structure of the small, flattened body located in the depression between the superior colliculi and which produces melatonin" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal glandula pinealis" EXACT []
synonym: "abnormal pineal body" EXACT []
synonym: "abnormal pineal gland" EXACT []
is_a: MT:0000631 ! neuroendocrine gland morphology
is_a: MT:0000840 ! epithalamus morphology

[Term]
id: MT:0000633
name: pituitary gland morphology
namespace: Trait.ontology
def: "anomalous structure of the compound gland suspended from the base of the hypothalamus, which secretes somatotropins, prolactin, TSH (thyroid-stimulating hormone), gonadotropins, adrenal corticotropin" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal hypophysis" EXACT []
synonym: "abnormal pituitary gland" EXACT []
is_a: MT:0000631 ! neuroendocrine gland morphology
is_a: MT:0000830 ! diencephalon morphology

[Term]
id: MT:0000637
name: susceptibility to ototoxicity-induced hearing loss
namespace: Trait.ontology
def: "sensitivity to reduction in hearing following exposure to an ototoxic compound" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000513 ! susceptibility to hearing loss

[Term]
id: MT:0000638
name: cochlear hair cell development
namespace: Trait.ontology
def: "initial production, differentiation, migration or maturation of the sensory epithelial cells of the cochlea" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0002622 ! cochlear hair cell morphology
is_a: MT:0003938 ! ear development

[Term]
id: MT:0000639
name: adrenal gland morphology
namespace: Trait.ontology
def: "malformed endocrine glands located above the kidney responsible for hormone and epinephrine secretion" [J:61190, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal adrenal gland" EXACT []
is_a: MT:0002163 ! gland morphology

[Term]
id: MT:0000643
name: adrenal central medulla morphology
namespace: Trait.ontology
def: "missing marrow like structure; cells here are responsible for secretion of epinephrine" [J:54931, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000639 ! adrenal gland morphology

[Term]
id: MT:0000646
name: adrenocortical cell morphology
namespace: Trait.ontology
def: "larger size of cells of the adrenal gland " [J:54931, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000639 ! adrenal gland morphology

[Term]
id: MT:0000647
name: sebaceous gland morphology
namespace: Trait.ontology
alt_id: MT:0001226
def: "malformation of the holocrine glands of the dermis that secrete sebum into the hair follicles" [tc:Teresa Chu_Mouse Genome Informatics Curator]
is_a: MT:0001216 ! epidermal layer morphology
is_a: MT:0002163 ! gland morphology

[Term]
id: MT:0000652
name: sebaceous gland size
namespace: Trait.ontology
alt_id: MT:0001229
def: "increased size of the sebum secreting glands of the hair shaft" [J:30249]
is_a: MT:0000647 ! sebaceous gland morphology

[Term]
id: MT:0000653
name: sex gland morphology
namespace: Trait.ontology
def: "anomalous structure of any of the organized aggregations of cells that function as secretory or excretory organs and are associated with reproduction" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_pig
synonym: "abnormal sex glands" EXACT []
is_a: MT:0002163 ! gland morphology

[Term]
id: MT:0000655
name: sex gland size
namespace: Trait.ontology
alt_id: MT:0001118
def: "enlargement in the volume of any of the sex glands" [J:62478]
synonym: "dilation of sex glands" EXACT []
is_a: MT:0000653 ! sex gland morphology
is_a: MT:0002160 ! reproductive system morphology

[Term]
id: MT:0000659
name: prostate gland size
namespace: Trait.ontology
alt_id: MT:0001160
def: "increased cell number in the prostate" [J:63764, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "hyperplastic prostate gland" EXACT []
is_a: MT:0001158 ! prostate morphology

[Term]
id: MT:0000660
name: lateral prostate size
namespace: Trait.ontology
alt_id: MT:0001161
def: "reduced cell number in the lateral lobe of the prostate" [J:63764, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "hypoplastic lateral prostate" EXACT []
is_a: MT:0000659 ! prostate gland size

[Term]
id: MT:0000661
name: ventral prostate size
namespace: Trait.ontology
alt_id: MT:0001162
def: "reduced size of lateral lobe of the prostate" [J:63764, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000659 ! prostate gland size

[Term]
id: MT:0000662
name: branching of the mammary ductal tree
namespace: Trait.ontology
def: "anomaly in the development of the channels that secrete milk and direct milk to the nipple" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000628 ! mammary gland development

[Term]
id: MT:0000664
name: small coagulating gland
namespace: Trait.ontology
alt_id: MT:0001164
def: "reduced size of the coagulating gland" [J:64981]
is_a: MT:0001163 ! coagulating gland morphology

[Term]
id: MT:0000665
name: ductal branching of the coagulating gland
namespace: Trait.ontology
alt_id: MT:0001165
def: "fewer branches and distal tips of the vesicles of the coagulating gland" [J:64981]
is_a: MT:0001163 ! coagulating gland morphology

[Term]
id: MT:0000666
name: number of prostate ducts
namespace: Trait.ontology
alt_id: MT:0001166
def: "fewer than normal minute canals that pass the prostatic secretions to the urethra" [J:63764, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001158 ! prostate morphology

[Term]
id: MT:0000672
name: mucin cell number
namespace: Trait.ontology
alt_id: MT:0001172
def: "fewer than normal number of cells that secrete fluid containing carbohydrate-rich glycoproteins" [J:54465, J:63764, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "reduced number of mucin cells" EXACT []
is_a: MT:0000317 ! cell number

[Term]
id: MT:0000674
name: sweat gland morphology
namespace: Trait.ontology
def: "anomalous structure of any of the coil glands of the skin that secrete sweat" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal sweat glands" EXACT []
is_a: MT:0002163 ! gland morphology

[Term]
id: MT:0000675
name: palmar eccrine gland morphology
namespace: Trait.ontology
def: "form, structure or size of the sweat glands of the palm" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal palmar eccrine glands" EXACT []
is_a: MT:0000674 ! sweat gland morphology
is_a: MT:0004271 ! paw/hand/foot/hoof morphology

[Term]
id: MT:0000676
name: water content
namespace: Trait.ontology
def: "more or less than the normal total amount of water retained in the body" [il:Ira Lu_Mouse Genome Informatics Curator]
subset: slim_pig
is_a: MT:0005451 ! body composition

[Term]
id: MT:0000678
name: parathyroid gland morphology
namespace: Trait.ontology
alt_id: MT:0001735
def: "anomalous structure of one of the two small, paired endocrine glands, usually found embedded in the connective tissue capsule on the posterior surface of the thyroid gland; they secrete parathyroid hormone (PTH) that regulates calcium and phosphorous metabolism" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal parathyroid glands" EXACT []
is_a: MT:0002163 ! gland morphology

[Term]
id: MT:0000681
name: thyroid gland morphology
namespace: Trait.ontology
alt_id: MT:0001737
def: "anomalous structure of the endocrine gland located in the front and to the sides of the upper part of the trachea and which secretes thyroid hormone and calcitonin" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal thyroid gland" EXACT []
is_a: MT:0002163 ! gland morphology

[Term]
id: MT:0000683
name: percent water in carcass
namespace: Trait.ontology
def: "less than the normal total amount of water retained in the body measured post mortem" [il:Ira Lu_Mouse Genome Informatics Curator]
is_a: MT:0000676 ! water content

[Term]
id: MT:0000685
name: immune system morphology
namespace: Trait.ontology
def: "morphological anomalies in the organs or cells associated with the development and formation of lymphocytes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "immune system abnormalities" EXACT []
synonym: "lymphoid system abnormalities" EXACT []
synonym: "lymphopoietic system abnormalities" EXACT []
is_a: MT:0005387 ! immune system trait

[Term]
id: MT:0000689
name: spleen morphology
namespace: Trait.ontology
alt_id: MT:0002226
def: "atypical structure of the organ that functions to filter blood and to store red corpuscles and platelets" [J:27463, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
synonym: "abnormal spleen structure" EXACT []
synonym: "spleen abnormalities" EXACT []
is_a: MT:0002396 ! hematopoietic system morphology/development
is_a: MT:0002722 ! immune system organ morphology

[Term]
id: MT:0000696
name: Peyer's patch morphology
namespace: Trait.ontology
def: "anomalous structure, development, or cellular make-up of the lymphoid tissue located on the mucosa of the small intestine" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal Peyer's patches" EXACT []
is_a: MT:0002339 ! lymph node morphology
is_a: MT:0002378 ! gut-associated lymphoid tissue morphology

[Term]
id: MT:0000700
name: lymph node number
namespace: Trait.ontology
def: "deviation from the normal number of lymph nodes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002339 ! lymph node morphology

[Term]
id: MT:0000701
name: lymph node size
namespace: Trait.ontology
def: "deviation from the normal lymph node size " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002221 ! lymph organ size
is_a: MT:0002339 ! lymph node morphology

[Term]
id: MT:0000703
name: thymus morphology
namespace: Trait.ontology
alt_id: MT:0002366
def: "anomalous structure or development of the primary lymphoid organ; required for immune system development" [J:55400, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal thymus structure" EXACT []
synonym: "thymus abnormalities" EXACT []
is_a: MT:0002396 ! hematopoietic system morphology/development
is_a: MT:0002722 ! immune system organ morphology

[Term]
id: MT:0000704
name: thymus development
namespace: Trait.ontology
def: "anomaly in the formation and/or differentiation of the thymus" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal development of the thymus" EXACT []
is_a: MT:0000703 ! thymus morphology

[Term]
id: MT:0000705
name: athymia
namespace: Trait.ontology
def: "absence of the primary lymphoid organ" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "Absence of Thymus" EXACT []
synonym: "absent thymus" EXACT []
is_a: MT:0000703 ! thymus morphology

[Term]
id: MT:0000711
name: thymic cortex cellularity
namespace: Trait.ontology
def: "reduced cell number in the outer portion of the thymus" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "hypoplasia of thymic cortex" EXACT []
is_a: MT:0002365 ! thymus cellularity
is_a: MT:0002371 ! thymus cortex morphology

[Term]
id: MT:0000712
name: vestibular hair cell development
namespace: Trait.ontology
def: "initial production, differentiation, migration or maturation of hair cells in the sensory epithelium of the maculae and cristae of the membranous labyrinth of the inner ear" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0002623 ! vestibular hair cell morphology
is_a: MT:0003938 ! ear development

[Term]
id: MT:0000713
name: Reichert's cartilage
namespace: Trait.ontology
def: "structure or formation of the cartilage found in the mesenchyme of the second pharyngeal arch in the embryo from which develop the stapes, styloid process, lesser horn and upper part of the body of the hyoid bone; its proximal end gives rise to the stylohyoid ligament" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000163 ! cartilage morphology
is_a: MT:0003935 ! craniofacial development
is_a: MT:0003938 ! ear development

[Term]
id: MT:0000715
name: thymocyte number
namespace: Trait.ontology
alt_id: MT:0000338
alt_id: MT:0000725
alt_id: MT:0001826
def: "fewer than expected number of precursors to T cells; these cells are lymphoid cells found in the thymus " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "decreased thymocyte number" EXACT []
synonym: "reduced thymocyte number" EXACT []
is_a: MT:0000717 ! lymphocyte number
is_a: MT:0002145 ! T lymphocyte development

[Term]
id: MT:0000716
name: immune system cell morphology
namespace: Trait.ontology
def: "anomalous structure, development, or number of immune cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
comment: new pslim term
subset: slim_cattle
subset: slim_pig
synonym: "abnormal immune cell" EXACT []
synonym: "immune system: cellular abnormalities" EXACT []
is_a: MT:0000685 ! immune system morphology

[Term]
id: MT:0000717
name: lymphocyte number
namespace: Trait.ontology
def: "deviation from the normal number of white blood cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_pig
synonym: "Abnormal Immune Cell Number" EXACT []
is_a: MT:0000221 ! WBC count
is_a: MT:0002401 ! lymphopoiesis
is_a: MT:0002619 ! lymphocyte morphology/development

[Term]
id: MT:0000729
name: myogenesis
namespace: Trait.ontology
def: "anomaly in embryonic formation of muscle cells or fibers" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "myogenesis abnormalities" EXACT []
is_a: MT:0000733 ! muscle development

[Term]
id: MT:0000731
name: collagen deposition in the muscles
namespace: Trait.ontology
def: "accumulation of collagen within the muscles" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0000733 ! muscle development

[Term]
id: MT:0000732
name: time of primary myocyte appearance
namespace: Trait.ontology
def: "development of initial muscle cells at a later time than is normal" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0000729 ! myogenesis

[Term]
id: MT:0000733
name: muscle development
namespace: Trait.ontology
def: "anomalous differentiation of muscle tissue" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "muscle development abnormalities" EXACT []
is_a: MT:0002108 ! muscle morphology

[Term]
id: MT:0000736
name: onset of muscle development
namespace: Trait.ontology
def: "late onset of the induction and/or differentiation of skeletal muscle" [J:18048]
is_a: MT:0000733 ! muscle development

[Term]
id: MT:0000737
name: myotome development
namespace: Trait.ontology
def: "malformation of or absence of the part of the somite that develops into the musculature" [J:29279, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000729 ! myogenesis

[Term]
id: MT:0000740
name: smooth muscle contractility
namespace: Trait.ontology
def: "inability or reduced ability of the smooth muscle to shorten or to develop increased tension" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005620 ! muscle contractility

[Term]
id: MT:0000741
name: detrusor smooth muscle contractility
namespace: Trait.ontology
def: "inability or reduced ability of the detrusor smooth muscle to shorten or to develop increased tension" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000740 ! smooth muscle contractility

[Term]
id: MT:0000742
name: ileal smooth muscle contractility
namespace: Trait.ontology
def: "inability or reduced ability of the ileal smooth muscle to shorten or to develop increased tension" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0004005 ! intestinal smooth muscle contractility

[Term]
id: MT:0000743
name: muscle spasms
namespace: Trait.ontology
alt_id: MT:0000744
def: "muscular twitching, cramps and seizures ; frequently associated with calcium deficiency, hypoparathyroidism, vitamin D deficiency or alkalosis " [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "muscle tetany" EXACT []
synonym: "muscle twitching" EXACT []
synonym: "tetanic cramps" EXACT []
is_a: MT:0002106 ! muscle physiology

[Term]
id: MT:0000747
name: muscle strength
namespace: Trait.ontology
def: "loss of muscle strength" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002106 ! muscle physiology

[Term]
id: MT:0000748
name: progressive muscle weakness
namespace: Trait.ontology
def: "increasing loss of strength over time" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:67994]
is_a: MT:0000747 ! muscle strength

[Term]
id: MT:0000749
name: muscle integrity
namespace: Trait.ontology
def: "pathological deterioration of muscle tissue, often accompanied by loss of function" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002106 ! muscle physiology

[Term]
id: MT:0000750
name: muscle regeneration
namespace: Trait.ontology
alt_id: MT:0002547
def: "inability or defects in ability to repair muscle after injuries" [J:42574]
synonym: "muscle regeneration" EXACT []
synonym: "muscle regeneration abnormalities" EXACT []
is_a: MT:0002106 ! muscle physiology

[Term]
id: MT:0000751
name: skeletal muscle integrity
namespace: Trait.ontology
def: "any abnormal condition or disease of the skeletal muscle" [J:42574, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000749 ! muscle integrity

[Term]
id: MT:0000753
name: ability to move
namespace: Trait.ontology
is_a: MT:0001388 ! stationary movement

[Term]
id: MT:0000755
name: ability to move the hindlimbs
namespace: Trait.ontology
is_a: MT:0000753 ! ability to move

[Term]
id: MT:0000756
name: ability to move the forelimbs
namespace: Trait.ontology
is_a: MT:0000753 ! ability to move

[Term]
id: MT:0000757
name: herniated abdominal wall
namespace: Trait.ontology
def: "protrusions through and/or into the abdominal wall often resulting in the extrusion of viscera" [J:40203, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abdominoschisis" EXACT []
synonym: "gastroschisis" EXACT []
synonym: "laparoschisis" EXACT []
synonym: "paraomphalocele" EXACT []
is_a: MT:0003257 ! abdominal wall morphology

[Term]
id: MT:0000759
name: skeletal muscle morphology
namespace: Trait.ontology
def: "anomalous structure of any of the striated muscle fibers connected at either or both extremities with the bony framework of the body" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "abnormal skeletal muscle" EXACT []
synonym: "skeletal muscle abnormalities" EXACT []
is_a: MT:0002108 ! muscle morphology

[Term]
id: MT:0000761
name: diaphragm muscle thickness
namespace: Trait.ontology
def: "reduced thickness of the diaphragm muscle" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:60159]
is_a: MT:0002279 ! diaphragm morphology

[Term]
id: MT:0000762
name: tongue morphology
namespace: Trait.ontology
def: "anomalous structure or development of the mobile mass of muscular tissue and surrounding epithelial tissue occupying the cavity of the mouth and forming part of the floor" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal tongue" EXACT []
synonym: "tongue abnormalities" EXACT []
is_a: MT:0000462 ! digestive system morphology

[Term]
id: MT:0000763
name: filiform papillae morphology
namespace: Trait.ontology
def: "malformed keratinized projections on the dorsal surface of the tongue" [J:45400]
synonym: "abnormal filiform papillae" EXACT []
is_a: MT:0000764 ! tongue epithelium morphology

[Term]
id: MT:0000764
name: tongue epithelium morphology
namespace: Trait.ontology
def: "malformation of the epithelial layer of the tongue" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8, tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "abnormal tongue epithelium" EXACT []
is_a: MT:0000762 ! tongue morphology

[Term]
id: MT:0000765
name: tongue squamous epithelium morphology
namespace: Trait.ontology
def: "malformation of the scaly epithelial layer of the tongue" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8, tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "abnormal tongue squamous epithelium" EXACT []
is_a: MT:0000764 ! tongue epithelium morphology

[Term]
id: MT:0000767
name: smooth muscle morphology
namespace: Trait.ontology
def: "anomalous structure of any of the unstriated muscle fibers of the internal organs, blood vessels, hair follicles, etc. " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "smooth muscle abnormalities" EXACT []
is_a: MT:0002108 ! muscle morphology

[Term]
id: MT:0000768
name: common crus morphology
namespace: Trait.ontology
def: "form or sttructure of the united, nonampullary ends of the superior and posterior semicircular ducts of the inner ear" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0002428 ! semicircular canal

[Term]
id: MT:0000771
name: brain size
namespace: Trait.ontology
def: "deviation from the average range of brain size for a given strain" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "brain size abnormalities" EXACT []
is_a: MT:0002152 ! brain morphology

[Term]
id: MT:0000776
name: inferior colliculus morphology
namespace: Trait.ontology
alt_id: MT:0000902
def: "dysmorphology or disorganization of the paired inferior eminence of the mesencephalic tectum that is involved in preliminary visual processing, and control of eye movements" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000899 ! colliculi morphology

[Term]
id: MT:0000777
name: inferior colliculus size
namespace: Trait.ontology
alt_id: MT:0000903
def: "enlargement of the paired inferior eminence of the mesencephalic tectum" [J:57538, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000776 ! inferior colliculus morphology
is_a: MT:0000900 ! colliculi size

[Term]
id: MT:0000778
name: tract morphology
namespace: Trait.ontology
def: "anomaly in the structure of any bundle of myelinated nerve fibers following a defined path through the brain and/or spinal cord" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
is_a: MT:0003632 ! nervous system morphology

[Term]
id: MT:0000779
name: cochlear basement membrane morphology
namespace: Trait.ontology
def: "form or structure of the continuous basement membrane found within the membranous labyrinth of the cochlea, known to extend from the limbus, down to the inner sulcus, across the basilar membrane, up to the external sulcus to the spiral prominence and radiating into the spiral ligament enseathing the root cell processes" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000031 ! cochlea morphology

[Term]
id: MT:0000780
name: corpus callosum morphology
namespace: Trait.ontology
def: "malformation or absence of a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres; it consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal corpus callosum" EXACT []
is_a: MT:0000787 ! telencephalon morphology
is_a: MT:0002199 ! brain commissure morphology

[Term]
id: MT:0000781
name: corpus callosum size
namespace: Trait.ontology
def: "smaller commissural plate interconnecting the cortical hemispheres of the brain" [J:38857, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000780 ! corpus callosum morphology

[Term]
id: MT:0000783
name: forebrain morphology
namespace: Trait.ontology
def: "malformed or absent anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [J:38857, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal forebrain" EXACT []
is_a: MT:0002152 ! brain morphology

[Term]
id: MT:0000784
name: forebrain cell number
namespace: Trait.ontology
def: "reduced cell number in the anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "hypoplastic forebrain" EXACT []
is_a: MT:0000783 ! forebrain morphology

[Term]
id: MT:0000785
name: telencephalon cell number
namespace: Trait.ontology
def: "reduced cell number in cerebral cortex and basal ganglia" [J:45302, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "hypoplastic cerebrum" EXACT []
synonym: "hypoplastic telencephalon" EXACT []
is_a: MT:0000787 ! telencephalon morphology

[Term]
id: MT:0000786
name: neuroepithelial layer differentiation
namespace: Trait.ontology
def: "malformation or arrest of differentiation or patterning of the epithelial layer of the brain" [J:45302]
is_a: MT:0000913 ! brain development
is_a: MT:0004261 ! embryonic neuroepithelium morphology

[Term]
id: MT:0000787
name: telencephalon morphology
namespace: Trait.ontology
alt_id: MT:0000782
def: "any malformation or absence of the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived " [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal cerebrum" EXACT []
synonym: "abnormal telencephalon" EXACT []
is_a: MT:0000783 ! forebrain morphology

[Term]
id: MT:0000788
name: cerebral cortex morphology
namespace: Trait.ontology
def: "malformed gray cellular mantle covering the surface of the brain" [J:38857, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal cerebral cortex" EXACT []
synonym: "abnormal neocortex" EXACT []
is_a: MT:0000787 ! telencephalon morphology

[Term]
id: MT:0000789
name: thickened cerebral cortex
namespace: Trait.ontology
def: "Increased depth of the mantle covering the surface of the cerebral hemispheres" [J:49481, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "thickened neocortex" EXACT []
is_a: MT:0000788 ! cerebral cortex morphology

[Term]
id: MT:0000791
name: cerebral cortex layer morphology
namespace: Trait.ontology
def: "splitting of the layers of the gray cellular mantle covering the surface of the brain" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:38857, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "delaminated neocortex" EXACT []
is_a: MT:0000788 ! cerebral cortex morphology

[Term]
id: MT:0000792
name: cortical marginal zone morphology
namespace: Trait.ontology
synonym: "abnormal cortical marginal zone" EXACT []
is_a: MT:0000934 ! telencephalon development

[Term]
id: MT:0000794
name: parietal lobe morphology
namespace: Trait.ontology
def: "malformation or absence of the upper central part of the cerebral hemisphere" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal parietal lobe" EXACT []
is_a: MT:0000788 ! cerebral cortex morphology

[Term]
id: MT:0000795
name: postcentral gyrus morphology
namespace: Trait.ontology
def: "malformation or absence of the area of the parietal lobe that receives general sensation from the body" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal postcentral gyrus" EXACT []
is_a: MT:0000794 ! parietal lobe morphology

[Term]
id: MT:0000796
name: sensory dissociation area morphology
namespace: Trait.ontology
def: "malformation or absence of the area of the parietal lobe that integrates tactile and visual stimuli" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal sensory dissociation area" EXACT []
is_a: MT:0000794 ! parietal lobe morphology

[Term]
id: MT:0000797
name: supramarginal gyrus morphology
namespace: Trait.ontology
def: "malformation or absence of the area of the frontal lobe that is involved in perception based on sensory stimuli" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal supramarginal gyrus" EXACT []
is_a: MT:0000794 ! parietal lobe morphology

[Term]
id: MT:0000798
name: frontal lobe morphology
namespace: Trait.ontology
def: "malformation or absence of the anterior part of the cerebral hemisphere" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal frontal lobe" EXACT []
is_a: MT:0000788 ! cerebral cortex morphology

[Term]
id: MT:0000799
name: precentral gyrus morphology
namespace: Trait.ontology
def: "malformation or absence of the area of the frontal lobe that contains the cell bodies of the primary motor pathways" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal primary motor area" EXACT []
is_a: MT:0000798 ! frontal lobe morphology

[Term]
id: MT:0000800
name: prefrontal gyrus morphology
namespace: Trait.ontology
def: "malformation or absence of the area of the frontal lobe that is involved with integration of voluntary movements and with speech" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal supplementary motor/speech area" EXACT []
is_a: MT:0000798 ! frontal lobe morphology

[Term]
id: MT:0000801
name: temporal lobe morphology
namespace: Trait.ontology
def: "malformation or absence of the lower lateral part of the cerebral hemisphere" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal temporal lobe" EXACT []
is_a: MT:0000788 ! cerebral cortex morphology

[Term]
id: MT:0000802
name: superior temporal gyrus morphology
namespace: Trait.ontology
synonym: "abnormal superior temporal gyrus" EXACT []
is_a: MT:0000801 ! temporal lobe morphology

[Term]
id: MT:0000803
name: transverse gyrus of Heschl morphology
namespace: Trait.ontology
def: "malformation or absence of the area of the temporal lobe concerned with hearing" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal primary auditory area" EXACT []
synonym: "abnormal transverse gyrus of Heschl" EXACT []
is_a: MT:0000801 ! temporal lobe morphology

[Term]
id: MT:0000804
name: occipital lobe morphology
namespace: Trait.ontology
def: "malformation or absence of the posterior part of the cerebral hemisphere" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal occipital lobe" EXACT []
is_a: MT:0000788 ! cerebral cortex morphology

[Term]
id: MT:0000805
name: visual cortex morphology
namespace: Trait.ontology
def: "malformation or absence of the area of the occipital cortex concerned with vision" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal striate cortex" EXACT []
synonym: "abnormal striate cortex morphology" EXACT []
is_a: MT:0000804 ! occipital lobe morphology

[Term]
id: MT:0000807
name: hippocampus morphology
namespace: Trait.ontology
alt_id: MT:0000806
alt_id: MT:0000810
def: "absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:38857, The Atlas of Mouse Development:ISBN 0-12-402035-6]
synonym: "abnormal hippocampus" EXACT []
synonym: "Hippocampal Defects" EXACT []
synonym: "Hippocampus" EXACT []
is_a: MT:0000787 ! telencephalon morphology
is_a: MT:0000801 ! temporal lobe morphology
is_a: MT:0004166 ! limbic system morphology

[Term]
id: MT:0000808
name: hippocampus development
namespace: Trait.ontology
def: "improper differentiation of the hippocampus" [tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "Abnormal Hippocampal Development" EXACT []
synonym: "Hippocampal Dysgenesis" EXACT []
is_a: MT:0000807 ! hippocampus morphology
is_a: MT:0000913 ! brain development

[Term]
id: MT:0000811
name: hippocampal neuron integrity
namespace: Trait.ontology
def: "a retrogressive impairment of function or destruction of the neuronal cells in the hippocampus" [cml:Cathleen M. Lutz_Mouse Genome Informatics Curator, J:72427]
synonym: "degenerating hippocampal neurons" EXACT []
is_a: MT:0002181 ! brain cell morphology
is_a: MT:0002882 ! neuron
is_a: MT:0003224 ! neuron integrity

[Term]
id: MT:0000812
name: dentate gyrus morphology
namespace: Trait.ontology
def: "absence or malformation of one of two interlocking gyri of the hippocampus that contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:38857, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal dentate gyrus" EXACT []
is_a: MT:0000807 ! hippocampus morphology

[Term]
id: MT:0000813
name: hippocampal laminar structure
namespace: Trait.ontology
def: "malformed or missing layers of the laminar structure of the hippocampus" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:38857, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal laminar structure" EXACT []
is_a: MT:0000807 ! hippocampus morphology

[Term]
id: MT:0000815
name: ammon gyrus morphology
namespace: Trait.ontology
def: "malformations of one of the two interlocking gyri of the hippocampus; a circonvolution of rhinencephalon, the grey substance of which is rich in big pyramidal neuronal cells " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal ammon gyrus" EXACT []
synonym: "abnormal Ammon horn" EXACT []
synonym: "abnormal Ammon's horn" EXACT []
is_a: MT:0000807 ! hippocampus morphology

[Term]
id: MT:0000816
name: cochlear hair cell stereociliary bundle morphology
namespace: Trait.ontology
def: "form or structure of he typical pattern of arrangement of mechanosensitive hair bundles which are composed of thick long microvilli (stereocilia) and are located at the apical end of cochlear inner and outer hair cells" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0002622 ! cochlear hair cell morphology

[Term]
id: MT:0000818
name: amygdala morphology
namespace: Trait.ontology
def: "any malformation or absence of the almond-shaped body of basal nuclei anterior to the inferior horn of the lateral ventricle of the brain, within the temporal lobe; this area is involved in aggression and fear responses" [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal amygdala" EXACT []
is_a: MT:0004166 ! limbic system morphology

[Term]
id: MT:0000819
name: olfactory bulb morphology
namespace: Trait.ontology
alt_id: MT:0000943
def: "malformation or absence of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [J:16461, Principles of Neural Science:ISBN 0-8385-8034-3, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal olfactory bulb" EXACT []
is_a: MT:0005235 ! olfactory pathway morphology

[Term]
id: MT:0000820
name: choroid plexus morphology
namespace: Trait.ontology
def: "malformed or absent fringe of the tela choroidea of the cerebral ventricles" [J:45302, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal choroid plexus" EXACT []
is_a: MT:0002200 ! brain ventricle/choroid plexus morphology

[Term]
id: MT:0000821
name: choroid plexus cell number
namespace: Trait.ontology
def: "increased cell number in the tela choroidea of the cerebral ventricles" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:49840, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "hyperplastic choroid plexus" EXACT []
is_a: MT:0000820 ! choroid plexus morphology

[Term]
id: MT:0000822
name: brain ventricle morphology
namespace: Trait.ontology
def: "malformed or absent fluid filled cavities of the cerebrum" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal brain ventricle" EXACT []
synonym: "abnormal ventricle" EXACT []
is_a: MT:0002200 ! brain ventricle/choroid plexus morphology

[Term]
id: MT:0000823
name: lateral ventricle morphology
namespace: Trait.ontology
def: "malformation or absence of cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube; they are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal lateral ventricles" EXACT []
is_a: MT:0000787 ! telencephalon morphology
is_a: MT:0000822 ! brain ventricle morphology

[Term]
id: MT:0000825
name: lateral ventricle size
namespace: Trait.ontology
alt_id: MT:0000824
def: "increase over the normal size of the horseshoe-shaped cavities of the cerebrum" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:38857, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "dilated ventricle of cerebral hemisphere" EXACT []
synonym: "dilated ventriculus lateralis" EXACT []
synonym: "enlarged lateral ventricles" EXACT []
is_a: MT:0000823 ! lateral ventricle morphology

[Term]
id: MT:0000826
name: third ventricle morphology
namespace: Trait.ontology
def: "malformation or absence of the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami; its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma; it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal third ventricle" EXACT []
is_a: MT:0000822 ! brain ventricle morphology
is_a: MT:0000830 ! diencephalon morphology

[Term]
id: MT:0000827
name: third ventricle size
namespace: Trait.ontology
def: "enlarged narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami; its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma; it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "dilated ventricle of diencephalon" EXACT []
synonym: "dilated ventriculus tertius" EXACT []
synonym: "enlarged third ventricle" EXACT []
is_a: MT:0000826 ! third ventricle morphology

[Term]
id: MT:0000828
name: fourth ventricle morphology
namespace: Trait.ontology
def: "malformed or absent irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind; it is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal fourth ventricle" EXACT []
synonym: "abnormal ventricle of rhombencephalon morphology" EXACT []
synonym: "abnormal ventriculus quartus morphology" EXACT []
is_a: MT:0000822 ! brain ventricle morphology
is_a: MT:0000841 ! hindbrain morphology

[Term]
id: MT:0000829
name: fourth ventricle size
namespace: Trait.ontology
def: "enlarged irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind; it is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "dilated ventricle of rhombencephalon" EXACT []
synonym: "dilated ventriculus quartus" EXACT []
synonym: "enlarged fourth ventricle" EXACT []
is_a: MT:0000828 ! fourth ventricle morphology

[Term]
id: MT:0000830
name: diencephalon morphology
namespace: Trait.ontology
def: "any malformation or absence of the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex" [MeSH:National Library of Medicine_Medical Subject Headings, Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal diencephalon" EXACT []
is_a: MT:0000783 ! forebrain morphology

[Term]
id: MT:0000831
name: diencephalon cell number
namespace: Trait.ontology
def: "increased cell number in the rostral portion of the brain stem" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:49840, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "hyperplastic diencephalon" EXACT []
is_a: MT:0000830 ! diencephalon morphology

[Term]
id: MT:0000832
name: thalamus morphology
namespace: Trait.ontology
def: "malformation or absence of the large ovoid mass of paired bodies containing mostly gray matter and forming part of the lateral wall of the third ventricle of the brain" [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal thalamus" EXACT []
is_a: MT:0000830 ! diencephalon morphology

[Term]
id: MT:0000833
name: thalamus cell number
namespace: Trait.ontology
def: "increased cell number in the thalamus" [J:49481, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "hyperplastic thalamus" EXACT []
is_a: MT:0000832 ! thalamus morphology

[Term]
id: MT:0000834
name: subthalamus morphology
namespace: Trait.ontology
def: "any malformation or absence of the anterior part of the diencephalon that lies between the thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis" [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal subthalamus" EXACT []
synonym: "abnormal ventral thalamus" EXACT []
is_a: MT:0000830 ! diencephalon morphology

[Term]
id: MT:0000835
name: subthalamic nucleus morphology
namespace: Trait.ontology
def: "any malformation or absence of the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function" [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal corpus luysi" EXACT []
synonym: "abnormal subthalamic nucleus" EXACT []
is_a: MT:0000834 ! subthalamus morphology
is_a: MT:0006007 ! basal ganglion morphology

[Term]
id: MT:0000836
name: substantia nigra morphology
namespace: Trait.ontology
def: "malformation or absence of the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis)" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal locus niger" EXACT []
synonym: "abnormal nucleus niger" EXACT []
synonym: "abnormal substantia nigra" EXACT []
is_a: MT:0000834 ! subthalamus morphology
is_a: MT:0006007 ! basal ganglion morphology

[Term]
id: MT:0000837
name: hypothalamus morphology
namespace: Trait.ontology
def: "any malformation or absence of the ventral part of the diencephalon extending from the region of the optic chiasm to the caudal border of the mammillary bodies and forming the inferior and lateral walls of the third ventricle; this region regulates the autonomic nervous system via hormone production and release" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal hypothalamus" EXACT []
is_a: MT:0000830 ! diencephalon morphology
is_a: MT:0004166 ! limbic system morphology

[Term]
id: MT:0000838
name: cochlear hair cell inter-stereocilial links
namespace: Trait.ontology
def: "form or structure of the morphologically and biochemically distinct link types that extend between the stereocilia of cochlear hair bundles; link types can be distinguished by their relative sensitivities to treatment with calcium chelators and the protease subtilisin; in the mature mouse cochlea, tip links and horizontal top connectors are the only inter-stereocilial links associated with the hair bundle; ankle links and transient lateral links are both prominent features of developing auditory hair bundles" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000816 ! cochlear hair cell stereociliary bundle morphology

[Term]
id: MT:0000839
name: hypothalamus cell number
namespace: Trait.ontology
def: "increased cell number in the hypothalamus" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:49840, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "hyperplastic hypothalamus" EXACT []
is_a: MT:0000837 ! hypothalamus morphology

[Term]
id: MT:0000840
name: epithalamus morphology
namespace: Trait.ontology
def: "any malformation or absence of the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle" [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000830 ! diencephalon morphology

[Term]
id: MT:0000841
name: hindbrain morphology
namespace: Trait.ontology
def: "malformed caudal region of the brain; includes cerebellum, pons and medulla oblongata" [J:45302, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002152 ! brain morphology

[Term]
id: MT:0000842
name: superior olivary complex morphology
namespace: Trait.ontology
def: "form or structure of the nucleus of neurons on the dorsal part of the lateral surface of the pons; it normally receives projection fibers from the cochlear nuclei and is prominently involved in spatial localization of sound	" [J:1776, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000848 ! pons morphology

[Term]
id: MT:0000843
name: facial nuclei cell number
namespace: Trait.ontology
def: "missing nucleus of neurons in the hindbrain; receives fibers from the facial muscles, stapedus muscle and stylohyoid muscle" [J:1776, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000909 ! facial motor nucleus morphology

[Term]
id: MT:0000844
name: pontine flexure morphology
namespace: Trait.ontology
def: "malformation or absence of the bend in the developing neural tube that produces a thinning of the roof of the pons and medulla oblongata and defines the boundary between the metencephalon and medulla oblongata in the embryo" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000841 ! hindbrain morphology
is_a: MT:0000913 ! brain development

[Term]
id: MT:0000846
name: medulla oblongata
namespace: Trait.ontology
alt_id: MT:0000845
def: "anomaly in the most caudal region of the brainstem that lies directly rostral to the spinal cord; includes regions responsible for autonomic functions such as digestion, breathing and control of heart rate" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal myelencephalon" EXACT []
is_a: MT:0000841 ! hindbrain morphology

[Term]
id: MT:0000847
name: metencephalon morphology
namespace: Trait.ontology
def: "any malformation or absence of the anterior part of the rhombencephalon" [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal metencephalon" EXACT []
is_a: MT:0000841 ! hindbrain morphology

[Term]
id: MT:0000848
name: pons morphology
namespace: Trait.ontology
def: "malformed band of nerve fibers in the brain connecting the medulla oblongata and the mesencephalon; this region conveys information about movement from the cerebral hemisphere to the cerebellum" [J:1776, Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000841 ! hindbrain morphology

[Term]
id: MT:0000849
name: cerebellum morphology
namespace: Trait.ontology
def: "any malformation or absence of the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement and learning of motor skills" [J:50311, Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal cerebellar hemispheres" EXACT []
synonym: "abnormal cerebellum" EXACT []
is_a: MT:0000841 ! hindbrain morphology

[Term]
id: MT:0000851
name: cerebellum cell number
namespace: Trait.ontology
def: "reduced cell number in the cerebellum" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:45302]
synonym: "hypoplastic cerebellum" EXACT []
is_a: MT:0000852 ! cerebellum size

[Term]
id: MT:0000852
name: cerebellum size
namespace: Trait.ontology
def: "reduced size of cerebellum" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:17203, J:67524]
is_a: MT:0000849 ! cerebellum morphology

[Term]
id: MT:0000854
name: cerebellum development
namespace: Trait.ontology
def: "malformed or incomplete differentiation of the part of the metencephalon that lies dorsal to the pons and medulla behind the brain stem and controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills " [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal cerebellar development" EXACT []
is_a: MT:0000849 ! cerebellum morphology
is_a: MT:0000913 ! brain development

[Term]
id: MT:0000855
name: formation of intralobular fissures
namespace: Trait.ontology
def: "formation of the major fissures of the cerebellum earlier in development than normal" [J:56546]
is_a: MT:0000854 ! cerebellum development

[Term]
id: MT:0000856
name: cerebellar plate morphology
namespace: Trait.ontology
def: "malformed embryonic pseudostratified epithelium of the fourth cerebellar ventricle that eventually forms the vermis and ventral neuroepithelium" [J:45302]
synonym: "abnormal cerebellar plate" EXACT []
is_a: MT:0000854 ! cerebellum development

[Term]
id: MT:0000857
name: cerebellar foliation
namespace: Trait.ontology
def: "malformation of small offshoots of the cerebellar lobules" [J:52951, Principles of Neural Science:ISBN 0-8385-8034-3]
is_a: MT:0000854 ! cerebellum development

[Term]
id: MT:0000858
name: metastatic potential
namespace: Trait.ontology
def: "altered likelihood of a tumor cell spreading from the site of the initial tumour formation and forming a secondary tumor at another site not directly connected with it" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002166 ! tumor susceptibility

[Term]
id: MT:0000859
name: somatosensory cortex morphology
namespace: Trait.ontology
def: "any malformation or absence of the area of the parietal lobe that lies posterior to the central sulcus and is concerned with receiving and processing general sensations from the body surface" [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000788 ! cerebral cortex morphology

[Term]
id: MT:0000860
name: primary somatosensory cortex morphology
namespace: Trait.ontology
def: "any malformation or absence of the area of the postcentral gyrus and central sulcus that is involved in somatic sensation" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
is_a: MT:0000859 ! somatosensory cortex morphology

[Term]
id: MT:0000861
name: barrel cortex organization
namespace: Trait.ontology
def: "arrangement of the pattern of the discrete functional units of the somatosensory cortex that processes tactile information derived from the vibrissae" [J:64064, Principles of Neural Science:ISBN 0-8385-8034-3]
is_a: MT:0003989 ! barrel cortex morphology

[Term]
id: MT:0000863
name: secondary somatosensory cortex morphology
namespace: Trait.ontology
def: "any malformation or absence of the area of the upper bank of the lateral sulcus that is involved in somatic sensation" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
is_a: MT:0000859 ! somatosensory cortex morphology

[Term]
id: MT:0000864
name: vermis morphology
namespace: Trait.ontology
def: "malformation in the narrow middle zone between the two hemispheres of the cerebellum" [J:61509, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000849 ! cerebellum morphology

[Term]
id: MT:0000865
name: vermis size
namespace: Trait.ontology
def: "length, width, or area of the narrow middle zone between the two hemispheres of the cerebellum" [J:45302, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000864 ! vermis morphology

[Term]
id: MT:0000866
name: vermis cell number
namespace: Trait.ontology
def: "reduced cell number in the vermis" [J:61509]
synonym: "hypoplastic vermis" EXACT []
is_a: MT:0000864 ! vermis morphology

[Term]
id: MT:0000867
name: anterior vermis morphology
namespace: Trait.ontology
def: "malformation in the anterior portion of the narrow middle zone between the two hemispheres of the cerebellum" [J:61509, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000864 ! vermis morphology

[Term]
id: MT:0000868
name: anterior vermis size
namespace: Trait.ontology
def: "smaller appearance of the narrow middle zone between the two hemispheres of the cerebellum" [J:57538, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000867 ! anterior vermis morphology

[Term]
id: MT:0000869
name: posterior vermis morphology
namespace: Trait.ontology
def: "malformation in the posterior portion of the narrow middle zone between the two hemispheres of the cerebellum" [J:61509, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000864 ! vermis morphology

[Term]
id: MT:0000870
name: vermal pyramis morphology
namespace: Trait.ontology
def: "form or structure of part of the inferior vermis of the cerebellum (vermis lobule VIII)" [J:61509, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "absence of vermal pyramis" EXACT []
is_a: MT:0000864 ! vermis morphology

[Term]
id: MT:0000871
name: vermal uvula morphology
namespace: Trait.ontology
def: "form or structure of the triangular elevation on the vermis of the cerebellum" [J:61509, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "absence of vermal uvula" EXACT []
is_a: MT:0000864 ! vermis morphology

[Term]
id: MT:0000872
name: external granule cell layer morphology
namespace: Trait.ontology
def: "malformation of the transient layer of the cerebellar cortex which is composed of the dividing and migrating granule cells" [tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "Abnormal EGL" EXACT []
synonym: "Abnormal External Germinal Layer" EXACT []
is_a: MT:0000854 ! cerebellum development

[Term]
id: MT:0000873
name: external granule cell layer thickness
namespace: Trait.ontology
def: "reduced thickness of the transient layer of the cerebellar cortex which is composed of dividing and migrating granule cells" [J:60896, tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "Thin EGL" EXACT []
synonym: "Thin External Germinal Layer" EXACT []
is_a: MT:0000872 ! external granule cell layer morphology

[Term]
id: MT:0000875
name: cerebellar Purkinje cell layer morphology
namespace: Trait.ontology
def: "any malformation or absence of the cell layer that lies just underneath the molecular layer of the cerebellar cortex; it contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer, and candelabrum interneurons are vertically oriented between the Purkinje cells" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal Purkinje cell layer" EXACT []
is_a: MT:0004097 ! cerebellar cortex morphology

[Term]
id: MT:0000876
name: Purkinje cell integrity
namespace: Trait.ontology
def: "a retrogressive impairment of function or destruction of the large neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex" [J:46854]
is_a: MT:0000877 ! Purkinje cell morphology
is_a: MT:0003224 ! neuron integrity

[Term]
id: MT:0000877
name: Purkinje cell morphology
namespace: Trait.ontology
def: "any structural anomaly of the neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex; these inhibitory neurons provide the output of the cerebellar cortex through axons that project into the white matter, and extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells" [J:46140, Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal Purkinje cells" EXACT []
is_a: MT:0000875 ! cerebellar Purkinje cell layer morphology
is_a: MT:0002882 ! neuron

[Term]
id: MT:0000878
name: Purkinje cell number
namespace: Trait.ontology
def: "different from average number of neuronal cells that are located in the interface of the molecular and granular layers of the cerebellar cortex" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000877 ! Purkinje cell morphology

[Term]
id: MT:0000881
name: cochlear hair bundle ankle links
namespace: Trait.ontology
def: "form or internal structure of the long, single-stranded filaments that form a dense web or mesh around the base of cochlear hair bundles just above the region in which the stereocilia begin to taper down; in the mouse, ankle links are only a transient feature of the developing cochlear hair bundles, present predominantly from P2 though P9, but are absent by P12; ankle links are disrupted by treatment of hair cells with EGTA and subtilisin but not by La^3+ and elastase" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000838 ! cochlear hair cell inter-stereocilial links

[Term]
id: MT:0000882
name: cochlear hair bundle horizontal top connectors
namespace: Trait.ontology
def: "form or internal structure of the inter-stereocilial links that connect the top of a shorter stereocilium to an adjacent longer stereocilium at a short distance below the tip links; the appearance of horizontal top connectors, which persist into adulthood, occurs concomitant with this loss of ankle links; top connectors are essentially unaffected by treatment with subtilisin and EGTA" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000838 ! cochlear hair cell inter-stereocilial links

[Term]
id: MT:0000883
name: cochlear hair bundle tip links
namespace: Trait.ontology
def: "form or internal structure of the single, three-stranded interrow filaments that extend obliquely from the tip of one stereocilium to the lateral side of an adjacent taller stereocilium; in the mouse, tip links are already detectable at E17 and persist throughout life; tips links are thought to gate the mechanotransducer channel, are lost from the cell surface after exposure to either calcium chelator BAPTA or lanthanum, and resist degradation by the protease subtilisin" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000838 ! cochlear hair cell inter-stereocilial links

[Term]
id: MT:0000884
name: Purkinje cell layer lamination
namespace: Trait.ontology
def: "splitting or disorganization of the layer of large neuron cell bodies between the molecular and granular layers of the cerebellum" [J:61509, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000875 ! cerebellar Purkinje cell layer morphology

[Term]
id: MT:0000885
name: ectopic Purkinje cell
namespace: Trait.ontology
def: "Purkinje cell body resides in places other than the Purkinje cell layer in the cerebellum" [J:60896, tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "ectopic Purkinje cell" EXACT []
synonym: "heterotopic Purkinje cell" EXACT []
is_a: MT:0000877 ! Purkinje cell morphology

[Term]
id: MT:0000886
name: cerebellar granule layer morphology
namespace: Trait.ontology
def: "any malformation or absence of the innermost cortical layer of the cerebellum; contains densely packed small neurons, mostly granule cells with some Golgi cells are found at the outer border" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal granule layer" EXACT []
synonym: "abnormal IGL" EXACT []
synonym: "abnormal internal granule layer" EXACT []
is_a: MT:0004097 ! cerebellar cortex morphology

[Term]
id: MT:0000887
name: granule layer lamination
namespace: Trait.ontology
def: "splitting or disorganization of the deepest of the three layers of the cerebellum that contains granule cells" [J:61509, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "delaminated internal granule layer" EXACT []
is_a: MT:0000886 ! cerebellar granule layer morphology

[Term]
id: MT:0000889
name: cerebellar molecular layer morphology
namespace: Trait.ontology
def: "any malformation or absence of the outermost layer of the cerebral cortex that contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells" [J:38857, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal molecular layer" EXACT []
is_a: MT:0004097 ! cerebellar cortex morphology

[Term]
id: MT:0000890
name: cerebellar molecular layer thickness
namespace: Trait.ontology
def: "reduced width of the outer of the three cortical layers of the cerebellum" [J:46854]
is_a: MT:0000889 ! cerebellar molecular layer morphology

[Term]
id: MT:0000891
name: cochlear hair bundle transient lateral links
namespace: Trait.ontology
def: "form or internal structure of the fine lateral links that interconnect stereocilia at E17.5; transient lateral links diminish at early postnatal stages (P2) when ankle links appear at the base of stereocilia, and are essentially unaffected by treatment with subtilisin and EGTA" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000838 ! cochlear hair cell inter-stereocilial links

[Term]
id: MT:0000892
name: orientation of cochlear hair cell stereociliary bundles
namespace: Trait.ontology
def: "rotational direction of inner and/or outer hair cell stereociliary bundles, resulting in planar cell polarity of the inner ear sensory epithelium" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000816 ! cochlear hair cell stereociliary bundle morphology

[Term]
id: MT:0000893
name: cochlear hair cell stereocilia number
namespace: Trait.ontology
def: "number of the nonmotile, actin-filled specialized microvilli (stereocilia) normally arrayed on cochlear inner and outer hair cells" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000816 ! cochlear hair cell stereociliary bundle morphology

[Term]
id: MT:0000894
name: cochlear hair cell stereocilia size
namespace: Trait.ontology
def: "length, width, or volume of the nonmotile, actin-filled specialized microvilli (stereocilia) which are normally arrayed on cochlear inner and outer hair cells" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000816 ! cochlear hair cell stereociliary bundle morphology

[Term]
id: MT:0000895
name: cochlear IHC afferent innervation
namespace: Trait.ontology
def: "the form, internal structure, or number of afferent terminals and/or their synapses in the cochlear IHC region" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000968 ! sensory neuron innervation
is_a: MT:0004393 ! cochlear inner hair cell morphology

[Term]
id: MT:0000896
name: cochlear IHC efferent innervation
namespace: Trait.ontology
def: "the form, internal structure, or number of the normally dense plexus of efferent terminals that contact radial fibers of the spiral ganglion below cochlear IHCs or of the sparser plexus of terminals positioned around IHC somata; normally, lateral olivocochlear neurons, which are found in and/or around the lateral superior olive, project mainly to the ipsilateral cochlea and terminate mostly on dendritic fibers below IHCs" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000968 ! sensory neuron innervation
is_a: MT:0004393 ! cochlear inner hair cell morphology

[Term]
id: MT:0000897
name: midbrain morphology
namespace: Trait.ontology
def: "malformation or malfunction associated with the middle of the three cerebral vesicles of the embryo; this region controls sensory and motor functions, including eye movement and coordination of auditory and visual reflexes" [J:23882, Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal mesencephalon" EXACT []
is_a: MT:0002152 ! brain morphology

[Term]
id: MT:0000898
name: midbrain cell number
namespace: Trait.ontology
def: "increased cell number associated with the middle of the three cerebral vesicles of the embryo" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:49840, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "hyperplastic midbrain" EXACT []
is_a: MT:0000897 ! midbrain morphology

[Term]
id: MT:0000899
name: colliculi morphology
namespace: Trait.ontology
def: "malformed inferior and superior colliculus" [J:50311]
is_a: MT:0006104 ! tectum morphology

[Term]
id: MT:0000900
name: colliculi size
namespace: Trait.ontology
def: "smaller inferior and superior colliculus" [J:19212, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000899 ! colliculi morphology

[Term]
id: MT:0000901
name: position of colliculi
namespace: Trait.ontology
def: "positional abnormality of the inferior and superior colliculus" [J:57538]
is_a: MT:0000899 ! colliculi morphology

[Term]
id: MT:0000904
name: superior colliculus
namespace: Trait.ontology
def: "dysmorphology or disorganization of the paired superior eminence of the mesencephalic tectum that is involved in auditory processing" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000899 ! colliculi morphology

[Term]
id: MT:0000905
name: superior colliculus size
namespace: Trait.ontology
def: "enlargement of the paired superior eminence of the mesencephalic tectum" [J:57538, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000900 ! colliculi size
is_a: MT:0000904 ! superior colliculus

[Term]
id: MT:0000906
name: mesencephalic trigeminal nucleus
namespace: Trait.ontology
def: "malformation or disorganization of the group of sensory neurons residing in a long, narrow plate in the midbrain; axons pass with the trigeminal nerve" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000897 ! midbrain morphology

[Term]
id: MT:0000907
name: mesencephalic trigeminal nucleus size
namespace: Trait.ontology
def: "reduced size of the group of sensory neurons residing in a long, narrow plate in the midbrain; axons pass with the trigeminal nerve" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:60159, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000906 ! mesencephalic trigeminal nucleus

[Term]
id: MT:0000909
name: facial motor nucleus morphology
namespace: Trait.ontology
def: "malformation or disorganization of the group of motor neurons residing in the pons that innervate the muscles of facial expression" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal motor nucleus, facial" EXACT []
is_a: MT:0000848 ! pons morphology

[Term]
id: MT:0000910
name: facial motor nucleus size
namespace: Trait.ontology
def: "reduced size of the group of motor neurons residing in the pons that innervate the muscles of facial expression" [J:56847, Principles of Neural Science:ISBN 0-8385-8034-3]
synonym: "small motor nucleus, facial" EXACT []
is_a: MT:0000909 ! facial motor nucleus morphology

[Term]
id: MT:0000911
name: trigeminal motor nucleus morphology
namespace: Trait.ontology
def: "malformation or disorganization of the group of motor neurons innervating the muscles of mastication" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal motor nucleus, trigeminal" EXACT []
is_a: MT:0000848 ! pons morphology

[Term]
id: MT:0000912
name: trigeminal motor nucleus size
namespace: Trait.ontology
def: "reduced size of the group of motor neurons innervating the muscles of mastication" [J:18984, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "small motor nucleus, trigeminal" EXACT []
is_a: MT:0000911 ! trigeminal motor nucleus morphology

[Term]
id: MT:0000913
name: brain development
namespace: Trait.ontology
alt_id: MT:0001888
def: "malformed or incomplete differentiation of the brain" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:49840]
synonym: "brain development abnormalities" EXACT []
xref: GO:0007420
is_a: MT:0002152 ! brain morphology
is_a: MT:0003861 ! nervous system development

[Term]
id: MT:0000914
name: exencephaly
namespace: Trait.ontology
def: "neurocranial defects resulting in exposure or extrusion of the brain" [J:49840, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000913 ! brain development

[Term]
id: MT:0000917
name: obstructive hydrocephaly
namespace: Trait.ontology
alt_id: MT:0001892
def: "hydrocephaly due to a block in cerebrospinal fluid flow in the ventricular system" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "obstructive hydrocephalus" EXACT []
is_a: MT:0001891 ! hydroencephaly

[Term]
id: MT:0000919
name: cranioschisis
namespace: Trait.ontology
def: "incomplete closure of the skull, usually congenital " [J:60409, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000438 ! skull morphology

[Term]
id: MT:0000920
name: myelination
namespace: Trait.ontology
alt_id: MT:0001894
def: "atypical or altered myelination in axon sheaths" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "altered myelination" EXACT []
synonym: "myelination abnormalities" EXACT []
synonym: "myelination defect" EXACT []
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0000921
name: demyelination
namespace: Trait.ontology
def: "loss of the myelin sheath without loss of axons or fiber tracts" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000920 ! myelination

[Term]
id: MT:0000923
name: roof plate morphology
namespace: Trait.ontology
def: "malformation or absence of a transient group of neuroepithelial cells located at the dorsal midline of the neural tube that profoundly influences the development of the vertebrate central nervous system" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal roof plate" EXACT []
synonym: "roof plate abnormalities" EXACT []
is_a: MT:0002151 ! neural tube morphology/development

[Term]
id: MT:0000925
name: floor plate morphology
namespace: Trait.ontology
def: "malformation or absence of a transient group of neuroepithelial cells located at the ventral midline of the neural tube that profoundly influences the development of the vertebrate central nervous system" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal floor plate" EXACT []
synonym: "floor plate abnormalities" EXACT []
is_a: MT:0002151 ! neural tube morphology/development

[Term]
id: MT:0000927
name: floor plate size
namespace: Trait.ontology
def: "reduced size of the floor plate" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000925 ! floor plate morphology

[Term]
id: MT:0000928
name: incomplete cephalic closure
namespace: Trait.ontology
def: "arrest of the fusion of the cephalic neural folds" [J:12622]
is_a: MT:0003720 ! neural tube closure

[Term]
id: MT:0000929
name: open neural tube
namespace: Trait.ontology
alt_id: MT:0000931
alt_id: MT:0005436
def: "incomplete invagination and fusion of the neuroepithelial layer in early development" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:53370, J:62571]
synonym: "failure of neural tube closure" EXACT []
synonym: "hydrocele spinalis" EXACT []
synonym: "schistorrhachis" EXACT []
synonym: "spina bifida" EXACT []
is_a: MT:0003720 ! neural tube closure

[Term]
id: MT:0000930
name: wavy neural tube
namespace: Trait.ontology
def: "undulations in the embryonic neural tube" [J:37888]
is_a: MT:0002151 ! neural tube morphology/development

[Term]
id: MT:0000933
name: rhombomere morphology
namespace: Trait.ontology
def: "malformation of the transverse segments in the hindbrain region of the developing neural tube" [J:1776, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal rhombomeres" EXACT []
is_a: MT:0003208 ! neuromere morphology
is_a: MT:0006108 ! hindbrain development

[Term]
id: MT:0000934
name: telencephalon development
namespace: Trait.ontology
def: "malformed or incomplete differentiation of the anterior division of the embryonic prosencephalon " [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:49840, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000787 ! telencephalon morphology
is_a: MT:0003232 ! forebrain development

[Term]
id: MT:0000935
name: folding of telencephalic vesicles
namespace: Trait.ontology
def: "malformation of the stereotypic invaginations forming the paired diverticula of the telencephalon" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:49840, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000934 ! telencephalon development

[Term]
id: MT:0000936
name: telencephalic vesicles size
namespace: Trait.ontology
def: "reduced size of the paired diverticula of the telencephalon, from which the forebrain develops" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:49840, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000934 ! telencephalon development

[Term]
id: MT:0000937
name: motor neuron morphology
namespace: Trait.ontology
def: "malformation or absence of cells that innervate an effector (muscle or glandular) tissue; responsible for transmission of motor impulses" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:60159, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal motor neuron" EXACT []
synonym: "motor neuron abnormalities" EXACT []
is_a: MT:0000955 ! spinal cord morphology
is_a: MT:0002882 ! neuron

[Term]
id: MT:0000938
name: motor neuron integrity
namespace: Trait.ontology
def: "retrogressive impairment of function or destruction of the cells that innervate an effector (muscle or glandular) tissue" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "loss of motor neurons" EXACT []
is_a: MT:0000937 ! motor neuron morphology
is_a: MT:0003224 ! neuron integrity

[Term]
id: MT:0000939
name: motor neuron number
namespace: Trait.ontology
def: "fewer than normal numbers of cells that innervate an effector (muscle or glandular) tissue" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:60159, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000937 ! motor neuron morphology

[Term]
id: MT:0000940
name: motor neuron innervation
namespace: Trait.ontology
def: "misprojection or failure to bundle motor axons to an effector tissue" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:60159, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal motor neuron projections" EXACT []
is_a: MT:0000937 ! motor neuron morphology
is_a: MT:0002184 ! innervation

[Term]
id: MT:0000941
name: motor neuron target finding
namespace: Trait.ontology
def: "failure of innervating neuron to stop at target site and form terminal arbors " [J:47439]
is_a: MT:0000937 ! motor neuron morphology

[Term]
id: MT:0000942
name: motor neuron axon growth
namespace: Trait.ontology
def: "innervating motor neuron projections grow past typical endplate target and extend to myotendenous ends of muscle" [J:33132]
synonym: "excessive motor neuron growth" EXACT []
is_a: MT:0000937 ! motor neuron morphology

[Term]
id: MT:0000944
name: cochlear OHC afferent innervation
namespace: Trait.ontology
def: "the form, internal structure, or number of afferent terminals and/or their synapses in the cochlear OHC region" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004399 ! cochlear outer hair cell morphology

[Term]
id: MT:0000952
name: CNS glia morphology
namespace: Trait.ontology
def: "anomalous structure, number or composition of non-neuronal cells of the central nervous system that form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal CNS glia morphology" EXACT []
synonym: "CNS glia abnormalities" EXACT []
is_a: MT:0003634 ! glia morphology

[Term]
id: MT:0000953
name: oligodendrocyte morphology
namespace: Trait.ontology
def: "anomalous structure, number or composition of the neuroglia of the central nervous system that form the insulating myelin sheath of axons in the CNS" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal oligodendrocytes" EXACT []
synonym: "abnormal oligoglia" EXACT []
is_a: MT:0000952 ! CNS glia morphology

[Term]
id: MT:0000954
name: oligodendrocyte progenitor number
namespace: Trait.ontology
def: "fewer cells that differentiate into a type of glial cell in the central nervous system" [J:15108]
synonym: "reduced oligodendrocyte progenitor numbers" EXACT []
is_a: MT:0000953 ! oligodendrocyte morphology

[Term]
id: MT:0000955
name: spinal cord morphology
namespace: Trait.ontology
def: "malformation or disorganization of the cylindrical tissue of the vertebral canal that extends from the medulla oblongata to the conus medullaris" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal spinal cord" EXACT []
synonym: "spinal cord abnormalities" EXACT []
is_a: MT:0003632 ! nervous system morphology

[Term]
id: MT:0000958
name: peripheral nervous system integrity
namespace: Trait.ontology
def: "a retrogressive impairment of function or destruction of the ganglia and peripheral nerves that lie outside the brain and spinal cord" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "degeneration of peripheral nervous system" EXACT []
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0000959
name: somatic sensory system morphology
namespace: Trait.ontology
synonym: "abnormal somatic sensory system" EXACT []
synonym: "somatic sensory system abnormalities" EXACT []
is_a: MT:0002752 ! somatic nervous system morphology

[Term]
id: MT:0000960
name: sensory ganglia morphology
namespace: Trait.ontology
def: "malformation or absence of a group of sensory neuron cell bodies" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:64962, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal sensory ganglia" EXACT []
synonym: "sensory ganglia abnormalities" EXACT []
is_a: MT:0000959 ! somatic sensory system morphology
is_a: MT:0001104 ! spinal ganglia morphology

[Term]
id: MT:0000961
name: dorsal root ganglia morphology
namespace: Trait.ontology
def: "malformed group of nerve cell bodies of each segmental nerve projecting from the spinal cord" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:60159, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal dorsal root ganglia" EXACT []
synonym: "dorsal root ganglia abnormalities" EXACT []
is_a: MT:0000959 ! somatic sensory system morphology
is_a: MT:0001104 ! spinal ganglia morphology

[Term]
id: MT:0000962
name: dorsal root ganglia organization
namespace: Trait.ontology
def: "loss of segmentation pattern of dorsal root ganglia; loss of regular spacing" [J:62022, J:62023]
is_a: MT:0000961 ! dorsal root ganglia morphology

[Term]
id: MT:0000963
name: fused dorsal root ganglia
namespace: Trait.ontology
def: "loss of DRG spacing pattern and the appearance of two or more ganglia as one" [J:62022, J:62023]
is_a: MT:0000961 ! dorsal root ganglia morphology

[Term]
id: MT:0000964
name: dorsal root ganglia size
namespace: Trait.ontology
def: "reduced size of the dorsal root ganglia" [J:17123]
is_a: MT:0000961 ! dorsal root ganglia morphology

[Term]
id: MT:0000965
name: sensory neuron morphology
namespace: Trait.ontology
def: "malformation or absence of cells that innervate an effector (muscle or glandular) tissue; responsible for transmission of sensory impulses" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:60159, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal sensory neurons" EXACT []
is_a: MT:0000959 ! somatic sensory system morphology
is_a: MT:0002882 ! neuron

[Term]
id: MT:0000967
name: sensory neuron projections
namespace: Trait.ontology
def: "misprojection or failure to bundle sensory axons to an effector tissue or to the spinal cord" [J:60159, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8/ CLS]
is_a: MT:0000968 ! sensory neuron innervation

[Term]
id: MT:0000968
name: sensory neuron innervation
namespace: Trait.ontology
def: "defective or incomplete supply of nerve fibers to sensory termini or to spinal cord" [J:31622]
is_a: MT:0000965 ! sensory neuron morphology
is_a: MT:0002184 ! innervation

[Term]
id: MT:0000969
name: nociceptor morphology
namespace: Trait.ontology
def: "anomalous structure of any of the peripheral receptors for pain, including receptors sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal nociceptors" EXACT []
is_a: MT:0000965 ! sensory neuron morphology

[Term]
id: MT:0000970
name: polymodal receptor morphology
namespace: Trait.ontology
def: "anomaly in a sensory receptor that may be stimulated by mechanical, thermal or chemical means" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal polymodal receptors" EXACT []
is_a: MT:0000965 ! sensory neuron morphology

[Term]
id: MT:0000971
name: thermoreceptor morphology
namespace: Trait.ontology
def: "anomalous structure of any of the cellular receptors that mediate the sense of temperature; in vertebrates, these are most often located under the skin" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal thermal receptors" EXACT []
is_a: MT:0000965 ! sensory neuron morphology

[Term]
id: MT:0000972
name: mechanoreceptor morphology
namespace: Trait.ontology
def: "anomaly in the receptors of the body, usually nerve termini, that respond to mechanical pressure or distortion" [J:34172, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal mechanoreceptors" EXACT []
is_a: MT:0000965 ! sensory neuron morphology

[Term]
id: MT:0000973
name: cutaneous/subcutaneous mechanoreceptor morphology
namespace: Trait.ontology
def: "malformed receptors that respond to mechanical pressure or distortion in the skin" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal cutaneous/subcutaneous mechanoreceptors" EXACT []
is_a: MT:0000972 ! mechanoreceptor morphology

[Term]
id: MT:0000974
name: hair guard neuron morphology
namespace: Trait.ontology
def: "anomaly of the subcutaneous mechanoreceptors that innervate guard hairs" [J:49472]
synonym: "abnormal hair guard neurons" EXACT []
is_a: MT:0000973 ! cutaneous/subcutaneous mechanoreceptor morphology

[Term]
id: MT:0000976
name: innervation of hair guard cells
namespace: Trait.ontology
def: "more robust innervation of the hair guard cells" [J:65163]
is_a: MT:0000974 ! hair guard neuron morphology

[Term]
id: MT:0000977
name: hair-tylotrich neuron morphology
namespace: Trait.ontology
def: "anomaly of the subcutaneous mechanoreceptors that innervate tylotrich hair follicles" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal hair-tylotrich neurons" EXACT []
is_a: MT:0000973 ! cutaneous/subcutaneous mechanoreceptor morphology

[Term]
id: MT:0000978
name: innervation of hair-tylotrich cells
namespace: Trait.ontology
def: "more robust innervation of the hair tylotrich cells" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000977 ! hair-tylotrich neuron morphology

[Term]
id: MT:0000979
name: hair-down neuron morphology
namespace: Trait.ontology
def: "anomaly of the subcutaneous mechanoreceptors that innervate vellus hairs" [J:49472]
synonym: "abnormal D-hair receptors" EXACT []
synonym: "abnormal hair-down neurons" EXACT []
is_a: MT:0000973 ! cutaneous/subcutaneous mechanoreceptor morphology

[Term]
id: MT:0000981
name: innervation of hair-down cells
namespace: Trait.ontology
def: "more robust innervation of the hair down cells" [J:65163]
is_a: MT:0000979 ! hair-down neuron morphology

[Term]
id: MT:0000982
name: Meissner's corpuscle morphology
namespace: Trait.ontology
def: "structural anomaly of any of the numerous oval bodies found in the dermal papillae of thick skin; believed to be mechanoreceptors for tactile sensation" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal oval corpuscle" EXACT []
synonym: "abnormal touch corpuscle" EXACT []
synonym: "normal Meissner's corpuscle" EXACT []
is_a: MT:0000973 ! cutaneous/subcutaneous mechanoreceptor morphology

[Term]
id: MT:0000983
name: Meissner's corpuscle size
namespace: Trait.ontology
def: "larger than average size of the dermal mechanoreceptors for tactile sensation " [J:65163]
synonym: "enlarged oval corpuscle" EXACT []
synonym: "enlarged touch corpuscle" EXACT []
is_a: MT:0000982 ! Meissner's corpuscle morphology

[Term]
id: MT:0000984
name: innervation of Meissner's corpuscle
namespace: Trait.ontology
def: "more robust supply of nerve fibers connected to any part of the numerous oval bodies found in the dermal papillae of thick skin and which are believed to be mechanoreceptors for tactile sensation" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000982 ! Meissner's corpuscle morphology

[Term]
id: MT:0000985
name: Merkel's receptor morphology
namespace: Trait.ontology
def: "structural anomaly of the modified epidermal cells located in the stratum basale and found mostly in areas where sensory perception is acute" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal Merkel's receptor" EXACT []
is_a: MT:0000973 ! cutaneous/subcutaneous mechanoreceptor morphology

[Term]
id: MT:0000986
name: Merkel's receptor number
namespace: Trait.ontology
def: "greater than the normal number of the modified epidermal cells located in the stratum basale and found mostly in areas where sensory perception is acute" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "increased numbers of Merkel's receptors" EXACT []
is_a: MT:0000985 ! Merkel's receptor morphology

[Term]
id: MT:0000987
name: innervation of Merkel's receptor
namespace: Trait.ontology
def: "more robust supply of nerve fibers connected to the modified epidermal cells located in the stratum basale and found mostly in areas where sensory perception is acute" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0000985 ! Merkel's receptor morphology

[Term]
id: MT:0000988
name: pacinian corpuscle morphology
namespace: Trait.ontology
def: "anomalous structure of any of the rapidly adapting mechanoreceptors found in subcutaneous tissue beneath both hairy and glabrous skin, and which normally contain an afferent nerve fiber surrounded by a capsule with multiple concentric layers" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal pacinian corpuscle" EXACT []
is_a: MT:0000973 ! cutaneous/subcutaneous mechanoreceptor morphology

[Term]
id: MT:0000989
name: Ruffini's corpuscle morphology
namespace: Trait.ontology
def: "anomaly in the sensory cells in the subcutaneous tissue of the digits specialized to transduce mechanical stimuli " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal Ruffini's corpuscle" EXACT []
is_a: MT:0000973 ! cutaneous/subcutaneous mechanoreceptor morphology

[Term]
id: MT:0000990
name: skeletal muscle mechanoreceptor morphology
namespace: Trait.ontology
def: "malformed receptors that respond to mechanical pressure or distortion in the skeletal muscle" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal muscle/skeletal mechanoreceptors" EXACT []
is_a: MT:0000972 ! mechanoreceptor morphology
is_a: MT:0002108 ! muscle morphology

[Term]
id: MT:0000991
name: primary muscle spindle morphology
namespace: Trait.ontology
def: "anomalous structure of the sensory organ in muscle; involved in the stretch reflex and sensitive to stretch velocity" [Principles of Neural Science:ISBN 0-8385-8034-3]
synonym: "abnormal muscle spindle-primary" EXACT []
is_a: MT:0004069 ! muscle spindle morphology

[Term]
id: MT:0000992
name: primary muscle spindle size
namespace: Trait.ontology
def: "area of the sensory organ in muscle; involved in the stretch reflex and is sensitive to stretch velocity" [J:23882, Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "absent muscle spindle -primary" EXACT []
is_a: MT:0000991 ! primary muscle spindle morphology

[Term]
id: MT:0000994
name: secondary muscle spindle morphology
namespace: Trait.ontology
def: "anomalous structure of the sensory organ in muscle; involved in the stretch reflex and not sensitive to stretch velocity" [What's wrong with my mouse?:ISBN 0-471-31639-3]
synonym: "abnormal muscle spindle-secondary" EXACT []
is_a: MT:0004069 ! muscle spindle morphology

[Term]
id: MT:0000995
name: secondary muscle spindle size
namespace: Trait.ontology
def: "area of the sensory organ in muscle; involved in the stretch reflex and is not sensitive to stretch velocity" [J:23882, What's wrong with my mouse?:ISBN 0-471-31639-3]
synonym: "absent muscle spindle -secondary" EXACT []
is_a: MT:0000994 ! secondary muscle spindle morphology

[Term]
id: MT:0000997
name: joint capsule morphology
namespace: Trait.ontology
def: "anomalous structure of the sac that encloses the articulating ends of bones participating in a synovial joint " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal joint capsule" EXACT []
is_a: MT:0002932 ! joint morphology

[Term]
id: MT:0000999
name: golgi tendon organ morphology
namespace: Trait.ontology
def: "anomalous structure of the sensory organ in muscle that is involved in regulating muscle tension" [Principles of Neural Science:ISBN 0-8385-8034-3]
synonym: "abnormal golgi tendon organ" EXACT []
is_a: MT:0000990 ! skeletal muscle mechanoreceptor morphology

[Term]
id: MT:0001001
name: chemoreceptor morphology
namespace: Trait.ontology
def: "anomalous structure of any of the cells specialized to detect chemical substances and relay that information centrally in the nervous system" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal chemoreceptors" EXACT []
is_a: MT:0000965 ! sensory neuron morphology

[Term]
id: MT:0001002
name: taste bud morphology
namespace: Trait.ontology
def: "anomalous structure of the small sensory organs located in the tongue that contain gustatory receptor cells, basal cells, and supporting cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal taste buds" EXACT []
is_a: MT:0001001 ! chemoreceptor morphology
is_a: MT:0005500 ! gustatory system morphology

[Term]
id: MT:0001003
name: olfactory receptor morphology
namespace: Trait.ontology
def: "anomalous structure of the specialized proteins within the neurons of the olfactory epithelium that normally bind and detect odorants " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal olfactory receptors" EXACT []
is_a: MT:0001001 ! chemoreceptor morphology
is_a: MT:0005499 ! olfactory system morphology
is_a: MT:0006092 ! olfactory neuron morphology

[Term]
id: MT:0001004
name: photoreceptor morphology
namespace: Trait.ontology
def: "structural or developmental anomaly of the receptors sensitive to light " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal photoreceptors" EXACT []
is_a: MT:0000965 ! sensory neuron morphology
is_a: MT:0003728 ! photoreceptor layer

[Term]
id: MT:0001005
name: rod morphology
namespace: Trait.ontology
def: "structural or developmental anomaly of the photoreceptors that contain rhodopsin" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal rods" EXACT []
is_a: MT:0001004 ! photoreceptor morphology

[Term]
id: MT:0001006
name: cone morphology
namespace: Trait.ontology
def: "structural or developmental anomaly of the retinal receptors that give rise to color vision" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal cones" EXACT []
is_a: MT:0001004 ! photoreceptor morphology

[Term]
id: MT:0001007
name: sympathetic system morphology
namespace: Trait.ontology
def: "malformation of the part of the autonomic nervous system that innervates smooth muscle, cardiac muscle and glands and mediates the body's response to stressful situations" [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal adrenergic system" EXACT []
synonym: "abnormal somatic sympathetic system" EXACT []
synonym: "abnormal thoracolumbar system" EXACT []
synonym: "sympathetic system abnormalities" EXACT []
is_a: MT:0002751 ! autonomic nervous system morphology

[Term]
id: MT:0001008
name: sympathetic ganglia morphology
namespace: Trait.ontology
def: "malformed or absent groups of neuronal cell bodies of the autonomic nervous system" [J:18048]
synonym: "sympathetic ganglia abnormalities" EXACT []
is_a: MT:0001007 ! sympathetic system morphology
is_a: MT:0001104 ! spinal ganglia morphology

[Term]
id: MT:0001009
name: paravertebral ganglia cell number
namespace: Trait.ontology
def: "increase in cell number of the group of neuronal cell bodies of the autonomic nervous system that are located at intervals along the sympathetic trunks" [J:18048]
synonym: "hyperplastic paravertebral ganglia" EXACT []
is_a: MT:0001008 ! sympathetic ganglia morphology

[Term]
id: MT:0001010
name: prevertebral ganglia cell number
namespace: Trait.ontology
def: "increase in cell number of the group of neuronal cell bodies of the autonomic nervous system that are located on the superior part of the abdominal aorta " [J:18048]
synonym: "hyperplastic prevertebral ganglia" EXACT []
is_a: MT:0001008 ! sympathetic ganglia morphology

[Term]
id: MT:0001011
name: superior cervical ganglion morphology
namespace: Trait.ontology
def: "malformation or absence of the group of neurons that is the largest of the sympathetic trunk; normally lies at the base of the skull and innervates the head and neck" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal superior cervical ganglion" EXACT []
is_a: MT:0001008 ! sympathetic ganglia morphology

[Term]
id: MT:0001013
name: superior cervical ganglion size
namespace: Trait.ontology
def: "increased size of the group of neurons that is the largest of the ganglia of the sympathetic trunk; normally lies at the base of the skull and innervates the head and neck" [J:17131]
is_a: MT:0001011 ! superior cervical ganglion morphology

[Term]
id: MT:0001016
name: middle cervical ganglion morphology
namespace: Trait.ontology
def: "malformation or absence of the small ganglion located at the level of the cricoid cartilage of the laryngeal wall" [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal middle cervical ganglion" EXACT []
is_a: MT:0001008 ! sympathetic ganglia morphology

[Term]
id: MT:0001017
name: stellate ganglion morphology
namespace: Trait.ontology
def: "malformation or absence of the group of neurons formed by the fusion of the inferior cervical and first thoracic ganglia" [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal cervicothoracic ganglion" EXACT []
synonym: "abnormal stellate ganglion" EXACT []
is_a: MT:0001008 ! sympathetic ganglia morphology

[Term]
id: MT:0001018
name: cochlear OHC efferent innervation
namespace: Trait.ontology
def: "the form, internal structure, or number of efferent terminals, occurring as clusters, in the cochlear OHC region; normally, medial olivocochlear neurons, which are primarily found in rostral and ventral periolivary regions, project mainly to the contralateral cochlea, and terminate directly on OHCs" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004399 ! cochlear outer hair cell morphology

[Term]
id: MT:0001019
name: L4 ganglion morphology
namespace: Trait.ontology
def: "malformation or absence of L4 ganglion" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal L4 ganglion" EXACT []
is_a: MT:0001008 ! sympathetic ganglia morphology

[Term]
id: MT:0001020
name: L4 ganglion size
namespace: Trait.ontology
def: "increased bulk size of the L4 ganglion" [J:34172]
synonym: "hypertrophy of L4 ganglion" EXACT []
is_a: MT:0001019 ! L4 ganglion morphology

[Term]
id: MT:0001022
name: L5 ganglion morphology
namespace: Trait.ontology
def: "malformation or absence of the L5 ganglion" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal L5 ganglion" EXACT []
is_a: MT:0001008 ! sympathetic ganglia morphology

[Term]
id: MT:0001023
name: L5 ganglion size
namespace: Trait.ontology
def: "increased bulk size of L5 ganglion" [J:34172]
synonym: "hypertrophy of L5 ganglion" EXACT []
is_a: MT:0001022 ! L5 ganglion morphology

[Term]
id: MT:0001025
name: sympathetic neuron morphology
namespace: Trait.ontology
def: "malformation or anomalous development of any of the neurons of the part of the autonomic nervous system that innervates smooth muscle, cardiac muscle and glands and mediates the body's response to stressful situations" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal sympathetic neurons" EXACT []
synonym: "sympathetic neuron abnormalities" EXACT []
is_a: MT:0001007 ! sympathetic system morphology

[Term]
id: MT:0001026
name: adrenergic neuron morphology
namespace: Trait.ontology
def: "malformation or absence of the neurons that release catecholamines at a synapse after an impulse" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal adrenergic neurons" EXACT []
synonym: "adrenergic neuron abnormalities" EXACT []
is_a: MT:0001025 ! sympathetic neuron morphology

[Term]
id: MT:0001027
name: adrenergic innervation
namespace: Trait.ontology
synonym: "adrenergic innervation abnormalities" EXACT []
is_a: MT:0001026 ! adrenergic neuron morphology
is_a: MT:0002184 ! innervation

[Term]
id: MT:0001028
name: outer hair cell stereociliary bundle morphology
namespace: Trait.ontology
def: "form, structure or number of the typical V or W-like pattern of arrangement of mechanosensitive hair bundles located at the apical end of cochlear OHCs; each hair bundle is normally composed of ~100 nonmotile, actin-filled microvilli (stereocilia) arranged in rows of increasing height and coupled to one another by morphologically distinct links: tip links, horizontal top connectors, shaft connectors, and ankle links; most hair bundles also possess a single motile kinocilium immediately adjacent to the tallest (outermost) row of stereocilia; a fifth link type, the kinocilial link, connects the kinocilium to its neighboring stereocilia" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000816 ! cochlear hair cell stereociliary bundle morphology
is_a: MT:0004399 ! cochlear outer hair cell morphology

[Term]
id: MT:0001031
name: outer hair cell stereocilia number
namespace: Trait.ontology
def: "number of the nonmotile, actin-filled specialized microvilli (stereocilia) normally arrayed on cochlear outer hair cells" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000893 ! cochlear hair cell stereocilia number
is_a: MT:0001028 ! outer hair cell stereociliary bundle morphology

[Term]
id: MT:0001032
name: peptidergic neuron morphology
namespace: Trait.ontology
def: "malformation or absence of the nerve fibers believed to release small peptides as their neurotransmitter" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal peptidergic neurons" EXACT []
synonym: "peptidergic neuron abnormalities" EXACT []
is_a: MT:0001025 ! sympathetic neuron morphology

[Term]
id: MT:0001033
name: parasympathetic system morphology
namespace: Trait.ontology
def: "malformation of the part of the autonomic nervous system that innervates smooth muscle, cardiac muscle and glands and regulates homeostasis" [J:53284, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal cholinergic system" EXACT []
synonym: "abnormal craniosacral system" EXACT []
synonym: "abnormal somatic parasympathetic system" EXACT []
synonym: "parasympathetic system abnormalities" EXACT []
is_a: MT:0002751 ! autonomic nervous system morphology

[Term]
id: MT:0001034
name: parasympathetic ganglia morphology
namespace: Trait.ontology
def: "malformation or absence of the ganglia of the parasympathetic nervous system, including the ciliary, pterygopalatine, submandibular, and otic ganglia in the cranial region and intrinsic (terminal) ganglia associated with target organs in the thorax and abdomen" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal parasympathetic ganglia" EXACT []
is_a: MT:0001033 ! parasympathetic system morphology

[Term]
id: MT:0001035
name: submandibular ganglion morphology
namespace: Trait.ontology
def: "malformation or absence of the ganglion associated with the lingual nerve" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal submandibular ganglion" EXACT []
is_a: MT:0001034 ! parasympathetic ganglia morphology

[Term]
id: MT:0001036
name: submandibular ganglion size
namespace: Trait.ontology
def: "reduced size of the small parasympathetic ganglion of the lingual nerve" [J:53284, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001035 ! submandibular ganglion morphology

[Term]
id: MT:0001037
name: parasympathetic neuron morphology
namespace: Trait.ontology
def: "malformed or absent neurons of the autonomic nervous system that are responsible for innervation of smooth muscle, cardiac muscle and glands" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal parasympathetic neurons" EXACT []
is_a: MT:0001033 ! parasympathetic system morphology

[Term]
id: MT:0001038
name: cholinergic neuron morphology
namespace: Trait.ontology
alt_id: MT:0001029
def: "malformation or absence of the neurons that utilize acetylcholine as a neurotransmitter " [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "cholinergic neuron abnormalities" EXACT []
is_a: MT:0001025 ! sympathetic neuron morphology
is_a: MT:0001037 ! parasympathetic neuron morphology
is_a: MT:0002882 ! neuron

[Term]
id: MT:0001039
name: cholinergic innervation
namespace: Trait.ontology
alt_id: MT:0001030
def: "malformation or absence of the supply of nerve fibers that utilize acetylcholine as a neurotransmitter" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "cholinergic innervation abnormalities" EXACT []
is_a: MT:0001038 ! cholinergic neuron morphology
is_a: MT:0002184 ! innervation

[Term]
id: MT:0001041
name: lacrimal gland cholinergic innervation
namespace: Trait.ontology
def: "supply of nerve fibers to the gland that secretes tears" [J:53284, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001039 ! cholinergic innervation

[Term]
id: MT:0001042
name: sublingual salivary gland cholinergic innervation
namespace: Trait.ontology
def: "supply of nerve fibers to the exocrine gland on the floor of the mouth that secretes saliva" [J:53284, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001039 ! cholinergic innervation

[Term]
id: MT:0001043
name: parotid salivary gland cholinergic innervation
namespace: Trait.ontology
def: "supply of nerve fibers to the exocrine gland lateral to the jaw that secretes saliva" [J:53284, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001039 ! cholinergic innervation

[Term]
id: MT:0001044
name: enteric nervous system morphology
namespace: Trait.ontology
def: "malformation or absence of the part of the autonomic nervous system that innervates the esophagus, stomach, small and large bowel" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal enteric nervous system" EXACT []
synonym: "enteric nervous system abnormalities" EXACT []
is_a: MT:0002751 ! autonomic nervous system morphology

[Term]
id: MT:0001045
name: enteric ganglia morphology
namespace: Trait.ontology
def: "any structural anomaly or deformity of the groups of nerve cell bodies associated with the enteric neurons" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal enteric ganglia" EXACT []
is_a: MT:0001044 ! enteric nervous system morphology

[Term]
id: MT:0001046
name: enteric neuron morphology
namespace: Trait.ontology
def: "malformed or absent neurons that innervate the esophagus, stomach, small and large bowel" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal enteric neurons" EXACT []
is_a: MT:0001044 ! enteric nervous system morphology

[Term]
id: MT:0001047
name: enteric cholinergic neuron morphology
namespace: Trait.ontology
def: "malformation or absence of the neurons that utilize acetylcholine as a neurotransmitter and innervate the esophagus, stomach, small and large bowel" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal enteric cholinergic neurons" EXACT []
is_a: MT:0001046 ! enteric neuron morphology

[Term]
id: MT:0001048
name: enteric neuron number
namespace: Trait.ontology
def: "missing neurons that innervate the esophagus, stomach, small and large bowel" [J:49471, Principles of Neural Science:ISBN 0-8385-8034-3]
synonym: "absence of enteric neurons" EXACT []
is_a: MT:0001046 ! enteric neuron morphology

[Term]
id: MT:0001049
name: enteric cholinergic innervation
namespace: Trait.ontology
def: "malformation or absence of the supply of nerve fibers that utilize acetylcholine as a neurotransmitter to the intestinal system" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001039 ! cholinergic innervation
is_a: MT:0001047 ! enteric cholinergic neuron morphology

[Term]
id: MT:0001051
name: somatic motor system morphology
namespace: Trait.ontology
synonym: "abnormal somatic motor system" EXACT []
synonym: "somatic motor system abnormalities" EXACT []
is_a: MT:0002752 ! somatic nervous system morphology

[Term]
id: MT:0001052
name: muscle innervation
namespace: Trait.ontology
def: "malformation or misprojection of sensory or motor nerves to targets in muscle" [J:75958]
synonym: "muscle innervation abnormalities" EXACT []
is_a: MT:0001051 ! somatic motor system morphology
is_a: MT:0002184 ! innervation

[Term]
id: MT:0001053
name: neuromuscular synapse morphology
namespace: Trait.ontology
def: "malformed or absent membrane to membrane contact of a motor axon and a muscle myofiber resulting in aberrant transmission of nerve impulses" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:47439, J:60159, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal neuromuscular junction" EXACT []
synonym: "neuromuscular synapse abnormalities" EXACT []
is_a: MT:0001051 ! somatic motor system morphology
is_a: MT:0002184 ! innervation

[Term]
id: MT:0001054
name: presynaptic differentiation
namespace: Trait.ontology
def: "inability of nerve terminals to find target and/or form terminal arbors for synaptic transmission" [J:61509]
is_a: MT:0001053 ! neuromuscular synapse morphology

[Term]
id: MT:0001055
name: postsynaptic differentiation
namespace: Trait.ontology
def: "inability of an effector cell to form a differentiated postsynaptic membrane in response to innervation" [J:61509]
is_a: MT:0001053 ! neuromuscular synapse morphology

[Term]
id: MT:0001056
name: cranial nerve morphology
namespace: Trait.ontology
def: "any anomaly, deformity, or malformation of any of the twelve nerves that emerge from the cranium as opposed to the spinal nerves" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:45302, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal cranial nerves" EXACT []
synonym: "cranial nerve abnormalities" EXACT []
is_a: MT:0002752 ! somatic nervous system morphology

[Term]
id: MT:0001059
name: optic nerve size
namespace: Trait.ontology
alt_id: MT:0001331
def: "wasting of the second cranial nerve which is responsible for conveying visual information from the retina to the brain" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "atrophic optic nerve" EXACT []
synonym: "atrophy of optic nerve" EXACT []
is_a: MT:0001330 ! optic nerve morphology

[Term]
id: MT:0001061
name: oculomotor nerve morphology
namespace: Trait.ontology
def: "malformation or misprojection of the 3rd cranial nerve, which normally sends motor fibers to the levator muscles of the eyelid and to the superior rectus, inferior rectus, and inferior oblique muscles of the eye; and also sends parasympathetic efferents to the muscles controlling pupillary constriction and accommodation" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal oculomotor nerve" EXACT []
synonym: "CN-III" EXACT []
synonym: "oculomotor nerve abnormalities" EXACT []
is_a: MT:0001056 ! cranial nerve morphology

[Term]
id: MT:0001062
name: oculomotor nerve size
namespace: Trait.ontology
def: "volume, width or length of the nerve of the extraocular muscles, iris and ciliary body" [J:19212, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001061 ! oculomotor nerve morphology

[Term]
id: MT:0001063
name: trochlear nerve morphology
namespace: Trait.ontology
def: "any malformation or misprojection of the 4th cranial nerve, which normally carries the motor innervation of the superior oblique muscles of the eye " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal trochlear nerve" EXACT []
synonym: "CN-IV" EXACT []
synonym: "trochlear nerve abnormalities" EXACT []
is_a: MT:0001056 ! cranial nerve morphology

[Term]
id: MT:0001064
name: trochlear nerve size
namespace: Trait.ontology
def: "length, width, or area of the nerve of the superior oblique muscle" [J:19212, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "absence of trochlear nerve" EXACT []
is_a: MT:0001063 ! trochlear nerve morphology

[Term]
id: MT:0001065
name: trigeminal nerve morphology
namespace: Trait.ontology
def: "malformed chief sensory nerve of the face and motor nerve of the muscles of mastication; has three major divisions: ophthalmic, maxillary and mandibular " [J:33038, Principles of Neural Science:ISBN 0-8385-8034-3, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal trigeminal nerve" EXACT []
synonym: "CN-V" EXACT []
synonym: "trigeminal nerve abnormalities" EXACT []
is_a: MT:0001056 ! cranial nerve morphology

[Term]
id: MT:0001067
name: mandibular nerve morphology
namespace: Trait.ontology
def: "form or structure of the third division of the trigeminal nerve " [J:33038, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "absence of mandibular nerve" EXACT []
is_a: MT:0001065 ! trigeminal nerve morphology

[Term]
id: MT:0001068
name: mandibular nerve branching morphology
namespace: Trait.ontology
def: "malformed or misprojected axons of the mandibular nerve" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:60159, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal branching of mandibular nerve" EXACT []
is_a: MT:0001067 ! mandibular nerve morphology

[Term]
id: MT:0001069
name: trigeminal nerve connections to hindbrain morphology
namespace: Trait.ontology
def: "structure of the axonal connections from the trigeminal ganglion to the pons and medulla oblongata" [J:33038]
synonym: "absence of trigeminal nerve connections to hindbrain" EXACT []
is_a: MT:0001065 ! trigeminal nerve morphology

[Term]
id: MT:0001070
name: abducens nerve morphology
namespace: Trait.ontology
def: "any anomaly, deformity, or malformation of the 6th cranial nerve, which originates in the abducens nucleus of the pons and sends motor fibers to the lateral rectus muscles of the eye" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abducens nerve abnormalities" EXACT []
synonym: "CN-VI" EXACT []
is_a: MT:0001056 ! cranial nerve morphology

[Term]
id: MT:0001071
name: facial nerve morphology
namespace: Trait.ontology
def: "malformed or misprojection of motor axons from the pons to the face" [J:29973, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal facial nerve" EXACT []
synonym: "CN-VII" EXACT []
synonym: "facial nerve abnormalities" EXACT []
is_a: MT:0001056 ! cranial nerve morphology

[Term]
id: MT:0001072
name: vestibulocochlear nerve morphology
namespace: Trait.ontology
def: "malformed sensory nerve innervating the receptor cells of the membranous labyrinth" [J:23837, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal vestibulocochlear nerve" EXACT []
synonym: "CN-VIII" EXACT []
synonym: "vestibulocochlear nerve abnormalities" EXACT []
is_a: MT:0001056 ! cranial nerve morphology

[Term]
id: MT:0001073
name: glossopharyngeal nerve morphology
namespace: Trait.ontology
def: "malformed or misprojection of sensory and autonomic axons to the parotid gland, carotid body, posterior third of the tongue" [J:33038, Principles of Neural Science:ISBN 0-8385-8034-3]
synonym: "abnormal glossopharyngeal nerve" EXACT []
synonym: "CN-IX" EXACT []
synonym: "glossopharyngeal nerve abnormalities" EXACT []
is_a: MT:0001056 ! cranial nerve morphology

[Term]
id: MT:0001074
name: vagus nerve morphology
namespace: Trait.ontology
def: "malformed or misprojection of autonomic, sensory and motor axons of the tenth cranial nerve to the pharynx, larynx, trachea, lungs, heart and GI tract" [J:33038, Principles of Neural Science:ISBN 0-8385-8034-3]
synonym: "abnormal vagus nerve" EXACT []
synonym: "CN-X" EXACT []
synonym: "vagus nerve abnormalities" EXACT []
is_a: MT:0001056 ! cranial nerve morphology

[Term]
id: MT:0001075
name: accessory nerve morphology
namespace: Trait.ontology
def: "any malformation or misprojection of the 11th cranial nerve, which normally originates from neurons in the medulla and in the cervical spinal cord" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal spinal accessory nerve" EXACT []
synonym: "abnormal spinal accessory nerve morphology" EXACT []
synonym: "CN-XI" EXACT []
synonym: "spinal accessory nerve abnormalities" EXACT []
is_a: MT:0001056 ! cranial nerve morphology

[Term]
id: MT:0001076
name: hypoglossal nerve morphology
namespace: Trait.ontology
def: "malformation or misprojection of motor axons to the tongue" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:45302, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal hypoglossal nerve" EXACT []
synonym: "CN-XII" EXACT []
synonym: "hypoglossal nerve abnormalities" EXACT []
is_a: MT:0001056 ! cranial nerve morphology

[Term]
id: MT:0001077
name: spinal nerve morphology
namespace: Trait.ontology
def: "any anomaly, deformity, or malformation of the any of the 31 paired peripheral nerves formed by the union of the dorsal and ventral spinal roots from each spinal cord segment" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal spinal nerves" EXACT []
synonym: "spinal nerve abnormalities" EXACT []
is_a: MT:0002752 ! somatic nervous system morphology

[Term]
id: MT:0001078
name: phrenic nerve morphology
namespace: Trait.ontology
def: "malformed or misprojection of motor and sensory neuron axons to the diaphragm and other tissues" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:60159, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001077 ! spinal nerve morphology

[Term]
id: MT:0001080
name: defasiculated phrenic nerve
namespace: Trait.ontology
def: "misprojection or failure to bundle motor and sensory neuron axons to the diaphragm and other tissues" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001078 ! phrenic nerve morphology

[Term]
id: MT:0001081
name: cranial ganglia morphology
namespace: Trait.ontology
def: "any anomaly, deformity, or malformation of the groups of nerve cell bodies associated with the twelve cranial nerves" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:45302, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal cranial ganglia" EXACT []
synonym: "cranial ganglia abnormalities" EXACT []
is_a: MT:0002752 ! somatic nervous system morphology

[Term]
id: MT:0001082
name: geniculate ganglion morphology
namespace: Trait.ontology
def: "malformed group of sensory neuron cell bodies associated with the facial nerve (seventh cranial nerve)" [J:45302, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal geniculate ganglion of facial (VII) nerve" EXACT []
synonym: "cranial ganglion VII" EXACT []
is_a: MT:0001081 ! cranial ganglia morphology

[Term]
id: MT:0001083
name: geniculate ganglion size
namespace: Trait.ontology
def: "reduced size of the geniculate ganglion or decreased size of sensory neuron cell bodies associated with the facial nerve" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001082 ! geniculate ganglion morphology

[Term]
id: MT:0001084
name: petrosal ganglion morphology
namespace: Trait.ontology
alt_id: MT:0001099
def: "malformation of the lower group of sensory neuron cell bodies associated with the glossopharyngeal nerve" [J:45302, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal extracraniale ganglion morphology" EXACT []
synonym: "abnormal inferior glossopharyngeal ganglion" EXACT []
synonym: "abnormal inferior glossopharyngeal ganglion of the glossopharyngeal (IX) nerve" EXACT []
synonym: "abnormal petrosal ganglion" EXACT []
is_a: MT:0001096 ! glossopharyngeal ganglion morphology

[Term]
id: MT:0001085
name: petrosal ganglion size
namespace: Trait.ontology
def: "reduced size of the petrosal ganglion" [J:25565]
is_a: MT:0001084 ! petrosal ganglion morphology

[Term]
id: MT:0001087
name: nodose ganglion morphology
namespace: Trait.ontology
alt_id: MT:0001103
def: "malformation of the large group of sensory neuron cell bodies, anterior to the jugular vein, associated with the vagus nerve (tenth cranial nerve)" [J:45302, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal inferior vagus ganglion" EXACT []
synonym: "abnormal inferior vagus ganglion of the vagus (X) nerve" EXACT []
synonym: "abnormal nodose ganglion" EXACT []
synonym: "cranial ganglion X" EXACT []
is_a: MT:0001100 ! vagus ganglion morphology

[Term]
id: MT:0001088
name: nodose ganglion size
namespace: Trait.ontology
def: "reduced size of the nodose ganglion" [J:17123, J:25565]
is_a: MT:0001087 ! nodose ganglion morphology

[Term]
id: MT:0001089
name: nodose ganglion neuron number
namespace: Trait.ontology
def: "count of the sensory neurons comprising the nodose ganglion" [J:45302, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001087 ! nodose ganglion morphology

[Term]
id: MT:0001091
name: outer hair cell stereocilia size
namespace: Trait.ontology
def: "length, width, or volume of the nonmotile, actin-filled specialized microvilli (stereocilia) which are normally arrayed on cochlear outer hair cells" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000894 ! cochlear hair cell stereocilia size
is_a: MT:0001028 ! outer hair cell stereociliary bundle morphology

[Term]
id: MT:0001092
name: trigeminal ganglion morphology
namespace: Trait.ontology
def: "malformed group of sensory neuron cell bodies associated with the trigeminal nerve (fifth cranial nerve)" [J:33038, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal Gasserian ganglion" EXACT []
synonym: "abnormal semilunar ganglion" EXACT []
synonym: "abnormal trigeminal ganglion of trigenmial (V) nerve" EXACT []
synonym: "cranial ganglion V" EXACT []
is_a: MT:0001081 ! cranial ganglia morphology

[Term]
id: MT:0001094
name: trigeminal ganglion cell size
namespace: Trait.ontology
def: "increased bulk size of trigeminal ganglion" [J:34172]
synonym: "hypertrophy of trigeminal ganglion" EXACT []
is_a: MT:0001092 ! trigeminal ganglion morphology

[Term]
id: MT:0001095
name: trigeminal ganglion size
namespace: Trait.ontology
def: "increased size of the group of sensory neuron cell bodies associated with the trigeminal nerve" [J:17131]
is_a: MT:0001092 ! trigeminal ganglion morphology

[Term]
id: MT:0001096
name: glossopharyngeal ganglion morphology
namespace: Trait.ontology
def: "malformed group of neuron cell bodies associated with the ninth cranial nerve" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal glossopharyngeal ganglia" EXACT []
synonym: "abnormal glossopharyngeal ganglia morphology" EXACT []
synonym: "cranial ganglion XI" EXACT []
is_a: MT:0001081 ! cranial ganglia morphology

[Term]
id: MT:0001097
name: superior glossopharyngeal ganglion morphology
namespace: Trait.ontology
def: "malformation of the upper ganglion of the glossopharyngeal nerve located at the jugular foramen" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal intracranial ganglion" EXACT []
synonym: "abnormal jugular ganglion" EXACT []
synonym: "abnormal superior glossopharyngeal ganglion of the glossopharyngeal (IX) nerve" EXACT []
is_a: MT:0001096 ! glossopharyngeal ganglion morphology

[Term]
id: MT:0001098
name: superior glossopharyngeal ganglion size
namespace: Trait.ontology
def: "reduced size of the upper ganglion of the glossopharyngeal nerve located at the jugular foramen" [J:18984, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001097 ! superior glossopharyngeal ganglion morphology

[Term]
id: MT:0001100
name: vagus ganglion morphology
namespace: Trait.ontology
def: "malformed group of sensory neuron cell bodies associated with the vagus nerve" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal vagus ganglia" EXACT []
synonym: "cranial ganglion X" EXACT []
is_a: MT:0001081 ! cranial ganglia morphology

[Term]
id: MT:0001101
name: superior vagus ganglion morphology
namespace: Trait.ontology
def: "malformation of the upper ganglion of the vagus nerve located at the jugular foramen" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal jugular ganglion" EXACT []
synonym: "abnormal superior vagus ganglion of the vagus (X) nerve" EXACT []
is_a: MT:0001100 ! vagus ganglion morphology

[Term]
id: MT:0001102
name: superior vagus ganglion size
namespace: Trait.ontology
def: "reduced size of the upper ganglion of the vagus nerve located at the jugular foramen" [J:18984, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001101 ! superior vagus ganglion morphology

[Term]
id: MT:0001104
name: spinal ganglia morphology
namespace: Trait.ontology
def: "any anomaly, deformity, or malformation of the groups of sensory nerve cell bodies located on the dorsal spinal roots within the vertebral column " [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal spinal ganglia" EXACT []
synonym: "spinal ganglia abnormalities" EXACT []
is_a: MT:0002752 ! somatic nervous system morphology

[Term]
id: MT:0001105
name: PNS glia morphology
namespace: Trait.ontology
def: "malformation or absence of non-neuronal cells that form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal neuroglia" EXACT []
synonym: "PNS glia abnormalities" EXACT []
is_a: MT:0003634 ! glia morphology

[Term]
id: MT:0001106
name: Schwann cell morphology
namespace: Trait.ontology
def: "malformed or absent cells which form the insulating myelin sheaths of peripheral axons" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal Schwann cells" EXACT []
synonym: "Schwann cell abnormalities" EXACT []
is_a: MT:0001105 ! PNS glia morphology

[Term]
id: MT:0001107
name: Schwann cell number
namespace: Trait.ontology
def: "fewer than normal cells that sheath the axons of the peripheral nervous system" [J:29971]
is_a: MT:0001106 ! Schwann cell morphology

[Term]
id: MT:0001116
name: gonad size
namespace: Trait.ontology
def: "reduced size of the testis or the ovary" [J:34193, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_pig
synonym: "hypogonad" EXACT []
synonym: "hypogonadism" EXACT []
is_a: MT:0002211 ! primary sex determination

[Term]
id: MT:0001119
name: female reproductive anatomy
namespace: Trait.ontology
def: "anomalous structure of the organs associated with producing offspring in the gender that bears the offspring" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_pig
is_a: MT:0002160 ! reproductive system morphology

[Term]
id: MT:0001120
name: uterus morphology
namespace: Trait.ontology
def: "malformation or absence of the female muscular organ of gestation" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
subset: slim_pig
is_a: MT:0001119 ! female reproductive anatomy

[Term]
id: MT:0001125
name: oocytes morphology
namespace: Trait.ontology
def: "anomalous structure of immature ova" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001931 ! oogenesis

[Term]
id: MT:0001126
name: ovary morphology
namespace: Trait.ontology
def: "malformed female reproductive gland containing the germ cells" [J:35782, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_pig
synonym: "abnormal gonad" EXACT []
synonym: "abnormal ovaries" EXACT []
is_a: MT:0000653 ! sex gland morphology
is_a: MT:0001119 ! female reproductive anatomy

[Term]
id: MT:0001127
name: ovary size
namespace: Trait.ontology
def: "reduced size of the female reproductive gland containing the germ cells" [J:35782, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_pig
synonym: "small ovaries" EXACT []
is_a: MT:0001116 ! gonad size
is_a: MT:0001126 ! ovary morphology

[Term]
id: MT:0001130
name: ovarian folliculogenesis
namespace: Trait.ontology
def: "atypical formation or failure to form the spherical ovum in the ovary" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:35782, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001131 ! ovarian follicle morphology

[Term]
id: MT:0001131
name: ovarian follicle morphology
namespace: Trait.ontology
def: "malformed or absent sac-like structure in the ovary which surrounds an ovum" [J:33042, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001126 ! ovary morphology

[Term]
id: MT:0001133
name: luteal cell differentiation
namespace: Trait.ontology
def: "abnormal development of the cells of the corpus luteum of the ovary" [J:33401, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002679 ! corpora lutea morphology

[Term]
id: MT:0001135
name: cervix morphology
namespace: Trait.ontology
def: "malformation or malfunctioning of the lower opening of the uterus to the vagina" [tc:Teresa Chu_Mouse Genome Informatics Curator]
is_a: MT:0001119 ! female reproductive anatomy

[Term]
id: MT:0001137
name: cervical epithelium morphology
namespace: Trait.ontology
def: "malformation of the epithelial layer of the cervix" [tc:Teresa Chu_Mouse Genome Informatics Curator]
is_a: MT:0001135 ! cervix morphology

[Term]
id: MT:0001138
name: cervical squamous epithelium morphology
namespace: Trait.ontology
def: "malformation of the scaly epithelial layer of the cervix" [J:54637, tc:Teresa Chu_Mouse Genome Informatics Curator]
is_a: MT:0001137 ! cervical epithelium morphology

[Term]
id: MT:0001139
name: vagina morphology
namespace: Trait.ontology
def: "malformation of the female reproductive canal located between the uterus and the vulva" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001119 ! female reproductive anatomy

[Term]
id: MT:0001140
name: vaginal epithelium
namespace: Trait.ontology
def: "malformation of the epithelial layer of the vagina" [J:54637, tc:Teresa Chu_Mouse Genome Informatics Curator]
is_a: MT:0001139 ! vagina morphology

[Term]
id: MT:0001141
name: thickened vaginal epithelium
namespace: Trait.ontology
def: "increased depth of the vaginal epithelial layer" [J:65045]
is_a: MT:0001140 ! vaginal epithelium

[Term]
id: MT:0001142
name: vaginal opening
namespace: Trait.ontology
def: "a malformed or absent opening to the genital canal" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001139 ! vagina morphology

[Term]
id: MT:0001143
name: vaginal opening size
namespace: Trait.ontology
def: "shrunken, narrowed external vaginal opening" [J:50844]
is_a: MT:0001142 ! vaginal opening

[Term]
id: MT:0001144
name: fused vaginal opening
namespace: Trait.ontology
def: "condition in which the external vaginal opening is closed by the adherence of the epithelium of the vagina" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001142 ! vaginal opening

[Term]
id: MT:0001145
name: male reproductive anatomy
namespace: Trait.ontology
def: "anomalous structure of the organs associated with producing offspring in the gender that produces spermatozoa" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_pig
is_a: MT:0002160 ! reproductive system morphology

[Term]
id: MT:0001146
name: testis morphology
namespace: Trait.ontology
def: "anomalous structure of the male reproductive glands" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_pig
synonym: "abnormal gonad" EXACT []
synonym: "abnormal testes" EXACT []
is_a: MT:0000653 ! sex gland morphology
is_a: MT:0001145 ! male reproductive anatomy

[Term]
id: MT:0001148
name: testes size
namespace: Trait.ontology
def: "increased size of the male reproductive glands" [J:63229, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_pig
synonym: "enlarged testis" EXACT []
synonym: "macroorchidism" EXACT []
is_a: MT:0001116 ! gonad size
is_a: MT:0001146 ! testis morphology

[Term]
id: MT:0001150
name: scrotum size
namespace: Trait.ontology
def: "increased size of the external sac of skin that encloses the testes" [J:65045, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002669 ! scrotum morphology

[Term]
id: MT:0001151
name: foreskin size
namespace: Trait.ontology
def: "increased size of the loose fold of skin that covers the penis" [J:65045]
is_a: MT:0003553 ! foreskin morphology

[Term]
id: MT:0001153
name: seminiferous tubule size
namespace: Trait.ontology
def: "reduced diameter of the tubules in the testes where spermatogenesis occurs" [J:50844]
synonym: "narrow seminiferous tubules" EXACT []
is_a: MT:0002216 ! seminiferous tubule morphology

[Term]
id: MT:0001154
name: seminiferous tubule integrity
namespace: Trait.ontology
def: "a retrogressive impairment of function or destruction of the tubules in the testes where spermatogenesis occurs" [J:50844]
synonym: "degeneration of seminiferous tubules" EXACT []
is_a: MT:0002216 ! seminiferous tubule morphology

[Term]
id: MT:0001156
name: spermatogenesis
namespace: Trait.ontology
def: "incomplete maturation or aberrant formation of the male gametes" [J:58959]
subset: slim_pig
synonym: "abnormal sperm development" EXACT []
is_a: MT:0001929 ! gametogenesis

[Term]
id: MT:0001158
name: prostate morphology
namespace: Trait.ontology
alt_id: MT:0000658
def: "malformed gland in males that secretes part of the seminiferous fluid" [J:63764, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000653 ! sex gland morphology
is_a: MT:0001145 ! male reproductive anatomy

[Term]
id: MT:0001163
name: coagulating gland morphology
namespace: Trait.ontology
alt_id: MT:0000663
def: "malformed or malfunctioning anterior lobe of the prostate" [J:64981]
synonym: "abnormal anterior prostate" EXACT []
is_a: MT:0001158 ! prostate morphology

[Term]
id: MT:0001168
name: prostate epithelial cell morphology
namespace: Trait.ontology
alt_id: MT:0000668
def: "abnormal development of the prostate epithelium" [J:63764]
is_a: MT:0001158 ! prostate morphology

[Term]
id: MT:0001169
name: bulbourethral gland morphology
namespace: Trait.ontology
alt_id: MT:0000669
def: "malformed gland in males that lies along the prostate gland and secretes a fluid component of the seminal fluid into the urethra	" [J:54465, J:63764, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal Cowper's gland" EXACT []
is_a: MT:0000653 ! sex gland morphology
is_a: MT:0001145 ! male reproductive anatomy

[Term]
id: MT:0001170
name: bulbourethral gland size
namespace: Trait.ontology
alt_id: MT:0000670
def: "increased cell number in the bulbourethral gland" [J:63764, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "Cowper's gland hyperplasia" EXACT []
synonym: "hyperplastic bulbourethral gland" EXACT []
synonym: "hyperplastic Cowper's gland" EXACT []
is_a: MT:0001169 ! bulbourethral gland morphology

[Term]
id: MT:0001173
name: number of ductal cells of the bulbourethral gland
namespace: Trait.ontology
alt_id: MT:0000673
def: "fewer than the normal number of cells found in the ducts through which the bulbourethral glands discharge mucus into the spongy part of the urethra" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "reduced number of ductal cells in the Cowper's gland" EXACT []
is_a: MT:0001169 ! bulbourethral gland morphology

[Term]
id: MT:0001175
name: lung morphology
namespace: Trait.ontology
def: "malformed organ of respiration" [J:35802]
subset: slim_chkn
synonym: "abnormal lung" EXACT []
is_a: MT:0002132 ! respiratory system morphology

[Term]
id: MT:0001176
name: lung development
namespace: Trait.ontology
def: "malformation or arrest of differentiation of the organs of respiration" [J:54931, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003115 ! respiratory system development

[Term]
id: MT:0001177
name: atelectasis
namespace: Trait.ontology
def: "collapse of the lung or any portion of the lung, or decreased or absent air in the lung, resulting in loss of lung volume" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:54931, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002133 ! respiratory system physiology

[Term]
id: MT:0001178
name: lung cell number
namespace: Trait.ontology
def: "reduced size of the respiratory organ due to reduced cell number in all or part of the organ" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology_2nd edition:ISBN 0-397-51047-0]
synonym: "hypoplastic lung" EXACT []
is_a: MT:0003641 ! lung size

[Term]
id: MT:0001179
name: alveolar septum thickness
namespace: Trait.ontology
def: "increased width of the structure that separates the air sacs (alveoli) in the lung" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "thick alveolar septa" EXACT []
is_a: MT:0002270 ! respiratory alveoli morphology

[Term]
id: MT:0001180
name: inner hair cell stereociliary bundle morphology
namespace: Trait.ontology
def: "form, internal structure, or number of the typically linear or U-shaped pattern of arrangement of mechanosensitive hair bundles located at the apical end of cochlear IHCs; each hair bundle is normally composed of ~100 nonmotile, actin-filled microvilli (stereocilia) arranged in rows of increasing height and coupled to one another by morphologically distinct links: tip links, horizontal top connectors, shaft connectors, and ankle links; most hair bundles also possess a single motile kinocilium immediately adjacent to the tallest row of stereocilia; a fifth link type, the kinocilial link, connects the kinocilium to its neighboring stereocilia" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000816 ! cochlear hair cell stereociliary bundle morphology
is_a: MT:0004393 ! cochlear inner hair cell morphology

[Term]
id: MT:0001183
name: respiratory alveoli size
namespace: Trait.ontology
def: "expanded volume of the saclike terminal dilation of the respiratory bronchioles" [J:66345]
synonym: "dilated alveoli" EXACT []
synonym: "enlarged alveoli" EXACT []
is_a: MT:0002270 ! respiratory alveoli morphology

[Term]
id: MT:0001186
name: pigmentation trait
namespace: Trait.ontology
subset: slim_cattle
subset: slim_pig
is_a: MT:0000001 ! Trait

[Term]
id: MT:0001188
name: pigment content
namespace: Trait.ontology
def: "excess of pigment in any or all tissues or a part of a tissue" [J:50311, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001186 ! pigmentation trait

[Term]
id: MT:0001189
name: skin pigmentation level
namespace: Trait.ontology
def: "concentration of pigmentation of the skin" [J:53370]
synonym: "albino" EXACT []
synonym: "pale skin" EXACT []
is_a: MT:0002095 ! skin pigmentation

[Term]
id: MT:0001190
name: reddish skin
namespace: Trait.ontology
def: "skin has a more intense ruddy appearance than normal, often due to capillary congestion" [J:65038]
synonym: "erythematous skin" EXACT []
is_a: MT:0002095 ! skin pigmentation

[Term]
id: MT:0001191
name: skin condition
namespace: Trait.ontology
def: "anomalous state of the skin" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_pig
is_a: MT:0002096 ! skin condition/ morphology

[Term]
id: MT:0001192
name: scaly skin
namespace: Trait.ontology
def: "skin covered with shedding scales or flakes" [J:65146]
is_a: MT:0001191 ! skin condition

[Term]
id: MT:0001193
name: psoriasis
namespace: Trait.ontology
def: "chronic skin lesions characterized by inflammation and silvery-scaly patches" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001191 ! skin condition

[Term]
id: MT:0001194
name: dermatitis
namespace: Trait.ontology
alt_id: MT:0001205
alt_id: MT:0001206
def: "inflammation of the skin" [J:65146]
synonym: "inflamed skin" EXACT []
synonym: "irritated skin" EXACT []
is_a: MT:0001846 ! tissue specific inflammatory response

[Term]
id: MT:0001195
name: flaky skin
namespace: Trait.ontology
def: "shedding scales on the skin " [J:56641]
is_a: MT:0001191 ! skin condition

[Term]
id: MT:0001196
name: shiny skin
namespace: Trait.ontology
def: "skin with a glossy or glistening appearance" [J:56641]
is_a: MT:0001191 ! skin condition

[Term]
id: MT:0001197
name: oily skin
namespace: Trait.ontology
def: "skin secreting an unusually high amount of oil, resulting in a glossy, shiny appearance" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001196 ! shiny skin

[Term]
id: MT:0001198
name: tight skin
namespace: Trait.ontology
def: "skin has a taut, stretched appearance" [J:65038]
synonym: "taut skin" EXACT []
is_a: MT:0001191 ! skin condition

[Term]
id: MT:0001200
name: skin thickness
namespace: Trait.ontology
def: "greater depth of skin" [J:47225]
subset: slim_pig
is_a: MT:0001191 ! skin condition

[Term]
id: MT:0001201
name: translucent skin
namespace: Trait.ontology
def: "skin that is transparent to light " [J:15108]
is_a: MT:0001191 ! skin condition

[Term]
id: MT:0001202
name: skin photosensitivity
namespace: Trait.ontology
def: "abnormally heightened reactivity of the skin to sunlight " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001191 ! skin condition
is_a: MT:0005501 ! skin physiology

[Term]
id: MT:0001204
name: skin irradiation susceptibility
namespace: Trait.ontology
def: "incidence of aberrant or damaged cells due to a given amount of irradiation induced genotoxic damage" [J:65162]
is_a: MT:0001191 ! skin condition
is_a: MT:0005501 ! skin physiology

[Term]
id: MT:0001208
name: blistering
namespace: Trait.ontology
def: "accumulation of fluid- filled thin walled structures under the epidermis or within the epidermis" [J:65039]
is_a: MT:0001191 ! skin condition

[Term]
id: MT:0001209
name: spontaneous skin ulceration
namespace: Trait.ontology
def: "unpredictable appearance of skin lesions, usually with inflammation" [J:65302]
synonym: "skin ulceration" EXACT []
is_a: MT:0001191 ! skin condition

[Term]
id: MT:0001210
name: thick skin ridges
namespace: Trait.ontology
def: "long raised strips of skin, usually aligned to the proximal-distal axis" [J:51296]
is_a: MT:0001191 ! skin condition

[Term]
id: MT:0001211
name: wrinkled skin
namespace: Trait.ontology
def: "irregular folds and/or indentations on the skin" [J:19212]
is_a: MT:0001191 ! skin condition

[Term]
id: MT:0001212
name: skin lesions
namespace: Trait.ontology
def: "focal patches of inflammation on the skin" [J:30162]
is_a: MT:0001191 ! skin condition

[Term]
id: MT:0001213
name: skin cell number
namespace: Trait.ontology
def: "greater than or fewer than the expected numbers of cells in the cutis" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002060 ! skin morphology

[Term]
id: MT:0001216
name: epidermal layer morphology
namespace: Trait.ontology
def: "anomalous structure or development of the superficial epithelial portion of the skin" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal epidermal layer" EXACT []
synonym: "abnormal epidermis" EXACT []
is_a: MT:0002060 ! skin morphology

[Term]
id: MT:0001219
name: epidermal layer thickness
namespace: Trait.ontology
def: "increase in the width of the epidermal cell layer in the skin" [J:65146]
is_a: MT:0001216 ! epidermal layer morphology

[Term]
id: MT:0001220
name: level of epidermal layer cell death
namespace: Trait.ontology
def: "pathological cell death in the epidermal layer of the skin, usually due to irreversible damage" [J:65146]
synonym: "necrotic epidermis" EXACT []
is_a: MT:0001216 ! epidermal layer morphology

[Term]
id: MT:0001221
name: epidermal layer integrity
namespace: Trait.ontology
def: "wasting of the epidermal layer of the skin" [J:65033]
is_a: MT:0001216 ! epidermal layer morphology

[Term]
id: MT:0001222
name: epidermal layer cell number
namespace: Trait.ontology
def: "increase in size of the epidermis due to increase in epidermal cell number" [J:65146, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001216 ! epidermal layer morphology

[Term]
id: MT:0001224
name: keratinocyte apoptosis
namespace: Trait.ontology
def: "aberrant programmed cell death of keratin producing cells of the epidermis" [J:64948]
xref: GO:0006915
xref: GO:0030216
is_a: MT:0002655 ! keratinocyte morphology

[Term]
id: MT:0001225
name: epidermal layer development
namespace: Trait.ontology
def: "abnormal development of the epidermis" [J:62478]
is_a: MT:0001216 ! epidermal layer morphology
is_a: MT:0003941 ! skin development

[Term]
id: MT:0001230
name: epidermal desquamation
namespace: Trait.ontology
def: "shedding of the cuticle of the epidermis in scales or shreds" [J:56777, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001216 ! epidermal layer morphology

[Term]
id: MT:0001231
name: basal cell layer morphology
namespace: Trait.ontology
def: "structural anomaly of the deepest layer of the epidermis, which is composed of dividing stem cells and anchoring cells" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal basal cell layer" EXACT []
synonym: "abnormal basal layer" EXACT []
synonym: "abnormal columnar layer" EXACT []
synonym: "abnormal germinative layer" EXACT []
synonym: "abnormal palisade layer" EXACT []
synonym: "abnormal stratum basale epidermis" EXACT []
synonym: "abnormal stratum cylindricum" EXACT []
synonym: "abnormal stratum germinativum" EXACT []
is_a: MT:0001216 ! epidermal layer morphology

[Term]
id: MT:0001233
name: suprabasal layer morphology
namespace: Trait.ontology
def: "malformed or atypical condition of the suprabasal layer of the skin" [J:56777]
synonym: "abnormal suprabasal layer" EXACT []
is_a: MT:0001231 ! basal cell layer morphology

[Term]
id: MT:0001235
name: suprabasal layer organization
namespace: Trait.ontology
def: "anomalous organization of the suprabasal layer of the skin" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0001233 ! suprabasal layer morphology

[Term]
id: MT:0001236
name: spinous layer morphology
namespace: Trait.ontology
def: "structual or developmental anomaly of the layer of polyhedral cells in the epidermis; shrinkage and adhesion of these cells gives a spiny or prickly appearance" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal prickle cell layer" EXACT []
synonym: "abnormal stratum spinosum" EXACT []
is_a: MT:0001216 ! epidermal layer morphology

[Term]
id: MT:0001237
name: spinous cell size
namespace: Trait.ontology
def: "increased size of the cells of the spinous layer of the epidermis" [J:47225]
synonym: "enlarged prickle cells" EXACT []
is_a: MT:0001236 ! spinous layer morphology

[Term]
id: MT:0001238
name: epidermal spinous layer thickness
namespace: Trait.ontology
def: "reduced thickness of the stratum spinosum; the polyhedral cell layer" [J:15108, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "thin prickle cell layer" EXACT []
synonym: "thin spinous layer" EXACT []
synonym: "thin stratum spinosum" EXACT []
is_a: MT:0001236 ! spinous layer morphology

[Term]
id: MT:0001239
name: granular layer morphology
namespace: Trait.ontology
def: "structural or developmental anomaly of the layer of flattened cells containing basophilic granules of keratohyalin and lying just above the stratum spinosum (spiny layer) of the epidermis" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal stratum granulosum" EXACT []
is_a: MT:0001216 ! epidermal layer morphology

[Term]
id: MT:0001240
name: cornified layer morphology
namespace: Trait.ontology
def: "structural or developmental anomaly of the outer layer of the epidermis, consisting of several layers of flat keratinized non-nucleated cells" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal horny layer" EXACT []
synonym: "abnormal stratum corneum" EXACT []
is_a: MT:0001216 ! epidermal layer morphology

[Term]
id: MT:0001242
name: cornified layer thickness
namespace: Trait.ontology
alt_id: MT:0001223
def: "increased depth of the corneal layer of the epidermis; thickening of the horny layer of the epidermis" [J:1133]
synonym: "epidermal hyperkeratosis" EXACT []
synonym: "thickened cornified layer" EXACT []
synonym: "thickened horny layer" EXACT []
synonym: "thickened stratum corneum" EXACT []
synonym: "thicker cornified layer" EXACT []
synonym: "thicker horny layer" EXACT []
synonym: "thicker stratum corneum" EXACT []
is_a: MT:0001240 ! cornified layer morphology

[Term]
id: MT:0001243
name: dermal layer morphology
namespace: Trait.ontology
def: "malformed or atypical condition of the dermal layer of the skin" [J:56777, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal corium" EXACT []
synonym: "abnormal cutis vera" EXACT []
synonym: "abnormal dermal layer" EXACT []
synonym: "abnormal dermis" EXACT []
is_a: MT:0002060 ! skin morphology

[Term]
id: MT:0001245
name: dermal layer thickness
namespace: Trait.ontology
def: "increased depth of the dermis" [J:65033]
synonym: "thick corium" EXACT []
synonym: "thick dermis" EXACT []
synonym: "thickened corium" EXACT []
synonym: "thickened dermal layer" EXACT []
synonym: "thickened dermis" EXACT []
is_a: MT:0001243 ! dermal layer morphology

[Term]
id: MT:0001246
name: mixed cellular infiltration to dermis
namespace: Trait.ontology
def: "gradual accumulation of mixed cell types in the dermis that are not normally found there" [J:65416]
is_a: MT:0001243 ! dermal layer morphology

[Term]
id: MT:0001247
name: dermal cysts
namespace: Trait.ontology
def: "abnormal membranous sacs appearing in the dermis" [J:53379]
is_a: MT:0001243 ! dermal layer morphology

[Term]
id: MT:0001248
name: connective tissue morphology
namespace: Trait.ontology
def: "missing supporting framework of a tissue or the body; formed of fibrous or ground substance" [J:56777, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "absence of connective tissue" EXACT []
is_a: MT:0005395 ! other trait

[Term]
id: MT:0001250
name: superficial dermis morphology
namespace: Trait.ontology
def: "anomalous structure of the more superficial, thin layer of the dermis that interdigitates with the epidermis" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal corpus papillary" EXACT []
synonym: "abnormal papillary layer" EXACT []
synonym: "abnormal stratum papillare" EXACT []
synonym: "abnormal stratum papillare corii" EXACT []
synonym: "abnormal superficial dermis" EXACT []
is_a: MT:0001243 ! dermal layer morphology

[Term]
id: MT:0001251
name: superficial dermis cellularity
namespace: Trait.ontology
def: "increased cell density of the superficial layer" [J:56777]
synonym: "hypercellularity of superficial dermis" EXACT []
is_a: MT:0001250 ! superficial dermis morphology

[Term]
id: MT:0001253
name: body height
namespace: Trait.ontology
def: "anomalous shoulder to floor distance compared to controls" [dlb:Donna Burkart_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_pig
xref: GO:0040007
xref: GO:0040014
is_a: MT:0003956 ! body size

[Term]
id: MT:0001256
name: body length
namespace: Trait.ontology
def: "anomalous crown to tail distance compared to controls" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_pig
xref: GO:0040007
xref: GO:0040014
is_a: MT:0003956 ! body size

[Term]
id: MT:0001259
name: body weight
namespace: Trait.ontology
def: "anomaly in average weight compared to controls" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0002089 ! postnatal growth/weight/body size

[Term]
id: MT:0001261
name: obese
namespace: Trait.ontology
def: "excessively fat; an increase in fat in the subcutaneous connective tissue" [cml:Cathleen M. Lutz_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "obesity" EXACT []
is_a: MT:0001259 ! body weight

[Term]
id: MT:0001263
name: weight loss
namespace: Trait.ontology
def: "progressive reduction of body weight below normal average for age" [J:45400]
subset: slim_cattle
subset: slim_chkn
is_a: MT:0001259 ! body weight

[Term]
id: MT:0001268
name: barrel chest
namespace: Trait.ontology
def: "distended circumference of the thoracic and abdominal areas" [J:55583]
is_a: MT:0004134 ! chest morphology

[Term]
id: MT:0001274
name: vibrissae shape
namespace: Trait.ontology
alt_id: MT:0001275
def: "physical form of the whiskers" [J:47620]
is_a: MT:0002098 ! vibrissae morphology

[Term]
id: MT:0001277
name: vibrissae pattern
namespace: Trait.ontology
def: "organization of the whiskers" [J:65301]
synonym: "tangled whiskers" EXACT []
is_a: MT:0002098 ! vibrissae morphology

[Term]
id: MT:0001280
name: vibrissae retention
namespace: Trait.ontology
def: "ability to retain the whiskers" [J:45400]
synonym: "loss of whiskers" EXACT []
is_a: MT:0002098 ! vibrissae morphology

[Term]
id: MT:0001281
name: vibrissae length
namespace: Trait.ontology
def: "longer average length of the whiskers" [J:65037]
synonym: "increased whisker length" EXACT []
is_a: MT:0002098 ! vibrissae morphology

[Term]
id: MT:0001283
name: vibrissae density
namespace: Trait.ontology
def: "few and widely spaced whiskers" [J:65302]
synonym: "sparse whiskers" EXACT []
is_a: MT:0002098 ! vibrissae morphology

[Term]
id: MT:0001286
name: eye development
namespace: Trait.ontology
def: "malformation or arrest of differentiation of the visual organ" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:49840, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "eye development abnormalities" EXACT []
xref: GO:0001654
is_a: MT:0002092 ! eye morphology

[Term]
id: MT:0001288
name: lens induction
namespace: Trait.ontology
def: "malformation of or failure to form the transparent, biconvex structure of the eye which is situated behind the iris and in front of the vitreous humor" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "lens induction abnormalities" EXACT []
is_a: MT:0005545 ! lens development

[Term]
id: MT:0001289
name: persistence of hyaloid capillary system
namespace: Trait.ontology
def: "failure of the degeneration of the transient vascular system of the eye during development" [J:49840]
is_a: MT:0001286 ! eye development

[Term]
id: MT:0001290
name: time of eyelid opening
namespace: Trait.ontology
def: "late average time for the first postnatal eye opening" [J:17792]
synonym: "delayed eye opening" EXACT []
is_a: MT:0003671 ! eyelid opening

[Term]
id: MT:0001292
name: lens vesicle development
namespace: Trait.ontology
def: "malformation or abnormal patterning of the lens vesicle of the eye" [J:49424]
synonym: "lens vesicle development abnormalities" EXACT []
is_a: MT:0001288 ! lens induction

[Term]
id: MT:0001293
name: anophthalmia
namespace: Trait.ontology
alt_id: MT:0001298
def: "congenital absence of all tissues of the eyes" [cml:Cathleen M. Lutz_Mouse Genome Informatics Curator, J:71979, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "absence of eyes" EXACT []
synonym: "absent eyes" EXACT []
is_a: MT:0002697 ! eye size

[Term]
id: MT:0001299
name: eye distance/ position
namespace: Trait.ontology
def: "abnormal placement of the eyes in relation to each other or in relation to other craniofacial structures" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "eye distance/ position abnormalities" EXACT []
is_a: MT:0002092 ! eye morphology

[Term]
id: MT:0001300
name: distance between the eyes
namespace: Trait.ontology
def: "increased distance between the eyes " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001299 ! eye distance/ position

[Term]
id: MT:0001301
name: inner hair cell stereocilia number
namespace: Trait.ontology
def: "number of the nonmotile, actin-filled specialized microvilli (stereocilia) normally arrayed on cochlear inner hair cells" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000893 ! cochlear hair cell stereocilia number
is_a: MT:0001180 ! inner hair cell stereociliary bundle morphology

[Term]
id: MT:0001303
name: lens morphology
namespace: Trait.ontology
def: "malformed transparent structure of the eye responsible for focusing light rays" [J:40203, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "lens abnormalities" EXACT []
is_a: MT:0002093 ! cornea/lens morphology

[Term]
id: MT:0001304
name: cataracts
namespace: Trait.ontology
def: "complete or partial opacity of the lens" [J:65031]
synonym: "cataract" EXACT []
synonym: "cataracts/ lens opacity" EXACT []
synonym: "lens opacity" EXACT []
is_a: MT:0001303 ! lens morphology
is_a: MT:0005545 ! lens development

[Term]
id: MT:0001305
name: lens size
namespace: Trait.ontology
def: "increased size of the transparent structure of the eye responsible for focusing light rays" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001303 ! lens morphology

[Term]
id: MT:0001307
name: fused cornea/lens
namespace: Trait.ontology
alt_id: MT:0001315
def: "condition in which the transparent anterior portion of the fibrous coat of the eye is joined to the transparent biconvex cellular refractive structure lying between the iris and vitreous humor of the eye" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "cornea/lens fusion" EXACT []
is_a: MT:0001312 ! cornea morphology
is_a: MT:0005545 ! lens development

[Term]
id: MT:0001308
name: lens polarity
namespace: Trait.ontology
def: "failure of normal orientation of the lens during development" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:49840, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal lens polarization" EXACT []
is_a: MT:0001292 ! lens vesicle development

[Term]
id: MT:0001309
name: hydropic eye lens fibers
namespace: Trait.ontology
def: "swollen cortical fibers of the eye lens" [J:14285]
is_a: MT:0002840 ! lens fiber morphology

[Term]
id: MT:0001310
name: conjunctiva morphology
namespace: Trait.ontology
def: "malformation or atrophy of the mucous membrane that lines the inner surface of the eyelids and the front of the eyeball" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "conjunctiva abnormalities" EXACT []
is_a: MT:0005193 ! anterior eye segment morphology

[Term]
id: MT:0001312
name: cornea morphology
namespace: Trait.ontology
def: "malformation or absence of the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure " [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "cornea abnormalities" EXACT []
is_a: MT:0002093 ! cornea/lens morphology

[Term]
id: MT:0001313
name: incidence of corneal inflammation
namespace: Trait.ontology
def: "greater than average and persistent occurrence of corneal irritation" [J:4606]
is_a: MT:0001312 ! cornea morphology
is_a: MT:0001846 ! tissue specific inflammatory response

[Term]
id: MT:0001314
name: corneal opacity
namespace: Trait.ontology
def: "complete or partial clouding of the cornea" [jte:Janan T. Eppig_Mouse Genome Informatics, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001312 ! cornea morphology

[Term]
id: MT:0001316
name: corneal scarring
namespace: Trait.ontology
def: "appearance of fibrous tissue on the cornea after healing in response to injury " [J:30249]
is_a: MT:0001312 ! cornea morphology

[Term]
id: MT:0001317
name: pupil morphology
namespace: Trait.ontology
def: "structural anomaly of the central circular aperture of the iris through which light rays enter the eye" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "pupil abnormalities" EXACT []
is_a: MT:0001322 ! iris morphology

[Term]
id: MT:0001318
name: pupil opacity
namespace: Trait.ontology
def: "milky or cloudy appearance of the central circular aperture of the iris through which light rays normally enter the eye" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001317 ! pupil morphology

[Term]
id: MT:0001319
name: irregularly shaped pupil
namespace: Trait.ontology
def: "shape defects in the aperture of the iris through which light rays enter the eye, usually circular " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "anisocoria" EXACT []
is_a: MT:0001317 ! pupil morphology

[Term]
id: MT:0001321
name: pupil size
namespace: Trait.ontology
def: "larger than normal size of the central circular aperture of the iris through which light rays enter the eye" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001317 ! pupil morphology

[Term]
id: MT:0001322
name: iris morphology
namespace: Trait.ontology
def: "structural anomaly of the adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "iris abnormalities" EXACT []
is_a: MT:0005194 ! anterior uvea morphology

[Term]
id: MT:0001323
name: inner hair cell stereocilia size
namespace: Trait.ontology
def: "length, width, or volume of the the nonmotile, actin-filled specialized microvilli (stereocilia) normally arrayed on cochlear inner hair cells" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000894 ! cochlear hair cell stereocilia size
is_a: MT:0001180 ! inner hair cell stereociliary bundle morphology

[Term]
id: MT:0001324
name: eye pigmentation
namespace: Trait.ontology
def: "change in the normal black pigmentation of the eye to another color, or lack of color" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001186 ! pigmentation trait
is_a: MT:0002092 ! eye morphology

[Term]
id: MT:0001325
name: retina morphology
namespace: Trait.ontology
def: "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "retina abnormalities" EXACT []
is_a: MT:0002864 ! ocular fundus morphology

[Term]
id: MT:0001326
name: retinal integrity
namespace: Trait.ontology
def: "pathological change in the thin layer of neural tissue lining the back of the eyeball, which contains visual receptors and can result in the impairment or cessation of retinal neural function" [NMF:Stephanie Pretel_Neuroscience Mutagenesis Facility Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005253 ! eye physiology

[Term]
id: MT:0001328
name: retinal layer organization
namespace: Trait.ontology
def: "delaminated or mispositioned sheets of cells comprising the optic part of the retina" [J:33400]
is_a: MT:0003727 ! retinal layer morphology

[Term]
id: MT:0001329
name: retina cell number
namespace: Trait.ontology
def: "greater than normal number of cells in the thin layer of neural tissue lining the back of the eyeball which contains visual receptors" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "hyperplastic retina" EXACT []
is_a: MT:0001325 ! retina morphology

[Term]
id: MT:0001330
name: optic nerve morphology
namespace: Trait.ontology
alt_id: MT:0001058
alt_id: MT:0001287
def: "malformation, misprojection or atrophy in the second cranial nerve which is responsible for conveying visual information from the retina to the brain; it extends from the retina to the optic chiasma where part of its fibers become the optic tract  and cross to the opposite side and pass to the geniculate bodies" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal optic disc" EXACT []
synonym: "abnormal optic disc morphology" EXACT []
synonym: "CN-II" EXACT []
synonym: "optic disc abnormalities" EXACT []
synonym: "optic nerve abnormalities" EXACT []
is_a: MT:0001056 ! cranial nerve morphology
is_a: MT:0005195 ! posterior eye segment morphology

[Term]
id: MT:0001332
name: optic nerve innervation
namespace: Trait.ontology
alt_id: MT:0001060
def: "misprojection or aberrant target finding of the second cranial nerve which is responsible for conveying visual information from the retina to the brain" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal innervation" EXACT []
synonym: "optic nerve innervation abnormalities" EXACT []
is_a: MT:0001330 ! optic nerve morphology

[Term]
id: MT:0001334
name: optic tract size
namespace: Trait.ontology
def: "volume, width, or length of the band of optic nerve fibers running from the optic chiasma to the lateral geniculate body and midbrain" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0004267 ! optic tract morphology

[Term]
id: MT:0001335
name: inner hair cell synaptic ribbon morphology
namespace: Trait.ontology
def: "form or internal structure of the presynaptic active zone of mature cochlear IHCs which usually contain a single synaptic ribbon, i.e. a submicrometer, electron-dense structure tethering synaptic vesicles; each spiral ganglion neuron receives input from only one IHC synapse " [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "IHC synaptic ribbon morphology" RELATED []
is_a: MT:0004393 ! cochlear inner hair cell morphology

[Term]
id: MT:0001336
name: active-zone-anchored inner hair cell synaptic ribbon morphology
namespace: Trait.ontology
def: "form or number of the usually single synaptic ribbon, a characteristic osmiophilic, electron-dense structure to which synaptic vesicles are tethered at the active zone of the cochlear inner hair cell afferent synapse" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0001335 ! inner hair cell synaptic ribbon morphology

[Term]
id: MT:0001337
name: eye moisture level
namespace: Trait.ontology
def: "absence of natural or normal moisture in the eye" [J:53284]
is_a: MT:0001348 ! lacrimal gland physiology

[Term]
id: MT:0001340
name: eyelid morphology
namespace: Trait.ontology
def: "malformation of the skin folds covering the front of the eyeball" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal eyelids" EXACT []
synonym: "eyelid abnormalities" EXACT []
is_a: MT:0002092 ! eye morphology

[Term]
id: MT:0001343
name: pronounced eyelids
namespace: Trait.ontology
def: "strongly protruding eyelids" [J:65032]
is_a: MT:0001340 ! eyelid morphology

[Term]
id: MT:0001344
name: blepharoptosis
namespace: Trait.ontology
alt_id: MT:0006161
def: "ptosis, drooping eyelids	" [J:24414, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "drooping eyelids" EXACT []
synonym: "ptosis" EXACT []
synonym: "ptosis of the eye" EXACT []
is_a: MT:0001340 ! eyelid morphology

[Term]
id: MT:0001345
name: meibomian gland size
namespace: Trait.ontology
alt_id: MT:0000651
def: "wasting of the sebaceous glands embedded in the tarsal plate of each eyelid resulting in reduced size" [J:65146]
synonym: "Atrophic Glandulae Tarsales" EXACT []
synonym: "atrophic glandulae tarsales" EXACT []
synonym: "atrophic meibomian glands" EXACT []
synonym: "Atrophic Tarsal Glands" EXACT []
synonym: "atrophic tarsal glands" EXACT []
synonym: "Palpebral Glands" EXACT []
is_a: MT:0005252 ! meibomian gland morphology

[Term]
id: MT:0001346
name: lacrimal gland morphology
namespace: Trait.ontology
alt_id: MT:0000682
def: "malformation of the glands that secrete tears" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8, tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "abnormal lachrymal glands" EXACT []
synonym: "abnormal lacrimal system" EXACT []
synonym: "abnormal tear ducts" EXACT []
is_a: MT:0002092 ! eye morphology
is_a: MT:0002163 ! gland morphology

[Term]
id: MT:0001348
name: lacrimal gland physiology
namespace: Trait.ontology
def: "aberrant function of the glands that secrete tears" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005253 ! eye physiology

[Term]
id: MT:0001349
name: tear production
namespace: Trait.ontology
def: "an unusually high amount of fluid secreted by the lacrimal glands, often resulting in overflow of fluid from the eye" [hdene:Howard Dene_Mouse Genome Informatics Curator, J:38104]
is_a: MT:0001348 ! lacrimal gland physiology

[Term]
id: MT:0001359
name: patterning of the organ of Corti
namespace: Trait.ontology
def: "organization of the various cell types within the organ of Corti into a set number of distinct rows" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000042 ! organ of Corti

[Term]
id: MT:0001360
name: social investigation
namespace: Trait.ontology
def: "altered behavior of animals to approach and examine other animals" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002557 ! social/conspecific interaction

[Term]
id: MT:0001365
name: Dieters cell number
namespace: Trait.ontology
def: "number of the supporting cells of the spiral organ which are attached to the basement membrane and receive the hair cells between their free extremities" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004302 ! Dieters cell morphology

[Term]
id: MT:0001366
name: pillar cell number
namespace: Trait.ontology
def: "number of the supporting cells that form the inner and outer walls of the tunnel in the organ of Corti " [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0003825 ! pillar cell morphology

[Term]
id: MT:0001373
name: spiral ligament integrity
namespace: Trait.ontology
def: "susceptibility of the spiral ligament to loss or degeneration" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0004288 ! spiral ligament morphology

[Term]
id: MT:0001375
name: mating preference
namespace: Trait.ontology
def: "deviation from the usual preference of a male to initiate sexual contact with a receptive female; usually refers to males that initiate sexual behavior with males and females indiscriminately" [J:76339]
is_a: MT:0002566 ! sexual interaction

[Term]
id: MT:0001376
name: mating receptivity
namespace: Trait.ontology
def: "deviation from the normal cycle or inability of females to respond favorably to males that initiate sexual behavior" [J:51468]
is_a: MT:0002566 ! sexual interaction

[Term]
id: MT:0001377
name: copulation
namespace: Trait.ontology
def: "reduced or absent attempt of sexual contact between a male and a receptive female" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002566 ! sexual interaction

[Term]
id: MT:0001378
name: ejaculation
namespace: Trait.ontology
def: "anomalies in the ability to propulse semen from the genital ducts and the urethra to the exterior" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003698 ! male reproductive system physiology

[Term]
id: MT:0001379
name: penile erection function
namespace: Trait.ontology
def: "altered ability to achieve a rigid and elevated state of the penis when the erectile tissue becomes filled with blood" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0003698 ! male reproductive system physiology

[Term]
id: MT:0001382
name: nursing
namespace: Trait.ontology
def: "females do not nurse pups or nurse pups infrequently" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001386 ! maternal nurturing

[Term]
id: MT:0001384
name: pup retrieval
namespace: Trait.ontology
def: "a mother does not retrieve stray pups to the nest or delays retrieving stray pups" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001386 ! maternal nurturing

[Term]
id: MT:0001385
name: pup cannibalization
namespace: Trait.ontology
def: "the killing and eating of newborn mice by the mother; can be a normal response if the mother does not recognize the pups as her own" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001386 ! maternal nurturing

[Term]
id: MT:0001386
name: maternal nurturing
namespace: Trait.ontology
alt_id: MT:0001381
def: "failure of mothers to tend offspring" [J:39801]
synonym: "abnormal care for newborns" EXACT []
synonym: "maternal nurturing defect" EXACT []
is_a: MT:0002068 ! parental behavior

[Term]
id: MT:0001387
name: spiral ligament size
namespace: Trait.ontology
def: "length, width, or area of the spiral ligament" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0004288 ! spiral ligament morphology

[Term]
id: MT:0001388
name: stationary movement
namespace: Trait.ontology
is_a: MT:0003491 ! voluntary movement

[Term]
id: MT:0001389
name: eye movements
namespace: Trait.ontology
is_a: MT:0001388 ! stationary movement
is_a: MT:0005253 ! eye physiology

[Term]
id: MT:0001391
name: tail movements
namespace: Trait.ontology
alt_id: MT:0000590
is_a: MT:0001388 ! stationary movement

[Term]
id: MT:0001392
name: locomotor activity
namespace: Trait.ontology
subset: slim_pig
synonym: "locomotion" EXACT []
is_a: MT:0003491 ! voluntary movement

[Term]
id: MT:0001393
name: coordination of voluntary muscular movement
namespace: Trait.ontology
is_a: MT:0001516 ! motor coordination/ balance
is_a: MT:0003312 ! locomotor coordination

[Term]
id: MT:0001398
name: strial basal cell tight junction morphology
namespace: Trait.ontology
def: "structure of the tight junctions between basal cells of stria vascularis, resulting in the paracellular barrier between basal cells; closing the intrastrial space off from the perilymph and establishing its electrical isolation" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0004365 ! strial basal cell morphology

[Term]
id: MT:0001399
name: activity level
namespace: Trait.ontology
alt_id: MT:0001397
alt_id: MT:0001403
is_a: MT:0003313 ! locomotor activation

[Term]
id: MT:0001404
name: spontaneous movement
namespace: Trait.ontology
is_a: MT:0003313 ! locomotor activation

[Term]
id: MT:0001406
name: gait
namespace: Trait.ontology
is_a: MT:0003312 ! locomotor coordination

[Term]
id: MT:0001407
name: stride length
namespace: Trait.ontology
is_a: MT:0003312 ! locomotor coordination

[Term]
id: MT:0001412
name: scratching
namespace: Trait.ontology
is_a: MT:0001440 ! grooming behavior

[Term]
id: MT:0001413
name: response to new environment
namespace: Trait.ontology
subset: slim_pig
is_a: MT:0001449 ! learning/ memory
is_a: MT:0003107 ! response to novelty

[Term]
id: MT:0001414
name: strial intermediate cell number
namespace: Trait.ontology
def: "number of the melanocytes (i.e. crest-derived intermediate cells) normally located within the intrastrial space; loss of strial intermediate cells is known to lead to loss of the endocochlear potential" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004367 ! strial intermediate cell morphology

[Term]
id: MT:0001416
name: strial marginal cell number
namespace: Trait.ontology
def: "number of the polarized columnar cells of epithelial origin which cover the lateral surface of the cochlear duct, secrete K+ and form a continuous sheet in contact with the endolymph" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004366 ! strial marginal cell morphology

[Term]
id: MT:0001417
name: exploration in new environment
namespace: Trait.ontology
subset: slim_pig
synonym: "exploration" RELATED []
is_a: MT:0001413 ! response to new environment

[Term]
id: MT:0001418
name: tectorial membran size
namespace: Trait.ontology
def: "length, width, or area of the tectorial membrane" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003149 ! tectorial membrane morphology

[Term]
id: MT:0001421
name: scala media size
namespace: Trait.ontology
def: "length, width, area, or volume of the scala media" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003169 ! scala media morphology

[Term]
id: MT:0001422
name: drinking behavior
namespace: Trait.ontology
is_a: MT:0002069 ! eating/drinking behavior

[Term]
id: MT:0001423
name: liquid preference
namespace: Trait.ontology
is_a: MT:0001422 ! drinking behavior

[Term]
id: MT:0001424
name: water consumption
namespace: Trait.ontology
is_a: MT:0001422 ! drinking behavior

[Term]
id: MT:0001425
name: alcohol consumption
namespace: Trait.ontology
synonym: "ethanol consumption" EXACT []
is_a: MT:0002568 ! response to addictive substances

[Term]
id: MT:0001429
name: dehydration
namespace: Trait.ontology
def: "excessive water loss from the body or from an organ or bodily part" [J:50053, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001784 ! fluid regulation

[Term]
id: MT:0001431
name: eating behavior
namespace: Trait.ontology
alt_id: MT:0001430
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0002069 ! eating/drinking behavior

[Term]
id: MT:0001432
name: food preference
namespace: Trait.ontology
subset: slim_chkn
is_a: MT:0001431 ! eating behavior

[Term]
id: MT:0001435
name: suckling reflex
namespace: Trait.ontology
is_a: MT:0001436 ! suckling behavior

[Term]
id: MT:0001436
name: suckling behavior
namespace: Trait.ontology
is_a: MT:0001431 ! eating behavior

[Term]
id: MT:0001437
name: swallowing reflex
namespace: Trait.ontology
is_a: MT:0001436 ! suckling behavior

[Term]
id: MT:0001440
name: grooming behavior
namespace: Trait.ontology
alt_id: MT:0001439
is_a: MT:0005386 ! behavior/neurological trait

[Term]
id: MT:0001444
name: scala tympani size
namespace: Trait.ontology
def: "length, width, area, or volume of the scala tympani" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003167 ! scala tympani morphology

[Term]
id: MT:0001445
name: vestibular hair cell stereociliary bundle morphology
namespace: Trait.ontology
def: "form, structure, number, or organization of the typical staircase-like arrangement of the mechanosensitive hair bundles which are composed of thick long microvilli (stereocilia) and are located at the apical end of vestibular hair cells of the utricle and saccule" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "vestibular hair bundle morphology" RELATED []
synonym: "vestibular hair cell stereocilia morphology" RELATED []
is_a: MT:0002623 ! vestibular hair cell morphology

[Term]
id: MT:0001446
name: whisker trimming
namespace: Trait.ontology
is_a: MT:0001440 ! grooming behavior

[Term]
id: MT:0001447
name: nest building behavior
namespace: Trait.ontology
is_a: MT:0002557 ! social/conspecific interaction

[Term]
id: MT:0001449
name: learning/ memory
namespace: Trait.ontology
subset: slim_pig
is_a: MT:0002063 ! learning/memory/conditioning

[Term]
id: MT:0001450
name: vestibular hair bundle inter-stereocilial links
namespace: Trait.ontology
def: "form, structure, or number of the morphologically and biochemically distinct link types that extend between the stereocilia of vestibular hair bundles" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0001445 ! vestibular hair cell stereociliary bundle morphology

[Term]
id: MT:0001451
name: vestibular hair bundle shaft connectors
namespace: Trait.ontology
def: "form, structure, or number of the links that connect the shafts of neighboring stereocilia in vestibular hair bundles; each shaft connector is composed of a ruthenium red-reactive, electron-dense particle that is connected to the plasma membrane by several fine strands of variable length" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0001450 ! vestibular hair bundle inter-stereocilial links

[Term]
id: MT:0001452
name: vestibular hair cell stereocilia number
namespace: Trait.ontology
def: "number of the nonmotile, actin-filled specialized microvilli (stereocilia) which are normally arrayed on vestibular hair cells in a staircase-like pattern" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001445 ! vestibular hair cell stereociliary bundle morphology

[Term]
id: MT:0001454
name: cued conditioning behavior
namespace: Trait.ontology
alt_id: MT:0001453
is_a: MT:0002062 ! conditioning behavior

[Term]
id: MT:0001455
name: vestibular hair cell stereocilia size
namespace: Trait.ontology
def: "lenght, width, or volume of the nonmotile, actin-filled specialized microvilli (stereocilia) which are normally arrayed on vestibular hair cells in a staircase-like pattern" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0001445 ! vestibular hair cell stereociliary bundle morphology

[Term]
id: MT:0001456
name: otic capsule size
namespace: Trait.ontology
def: "length, width, area, or volume of the cartilage or bony capsule surrounding the inner ear mechanism" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000039 ! otic capsule morphology

[Term]
id: MT:0001457
name: vestibular dark cell morphology
namespace: Trait.ontology
def: "form or structure of he nonsensory epithelial cells located above the vestibular melanocytes and adjacent to the sensory structures in the utricle and in the ampullae at the ends of each of the semicircular canals; these cells provide and maintain the high K+ ionic environment within the vestibular labyrinth and are therefore homologous to the marginal cells of the stria vascularis; they are joined to each other by tight junctions and provide a barrier between endolymph and perilymph" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000034 ! vestibule morphology

[Term]
id: MT:0001458
name: object recognition memory
namespace: Trait.ontology
is_a: MT:0001449 ! learning/ memory

[Term]
id: MT:0001459
name: vestibule size
namespace: Trait.ontology
def: "length, width, area, or volume of the vestibule" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000034 ! vestibule morphology

[Term]
id: MT:0001460
name: olfactory -discrimination memory
namespace: Trait.ontology
is_a: MT:0002802 ! discrimination learning

[Term]
id: MT:0001461
name: vestibular dark cell integrity
namespace: Trait.ontology
def: "susceptibility of vestibular dark cells to loss or degeneration" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001457 ! vestibular dark cell morphology

[Term]
id: MT:0001462
name: avoidance learning behavior
namespace: Trait.ontology
is_a: MT:0002062 ! conditioning behavior

[Term]
id: MT:0001463
name: spatial learning
namespace: Trait.ontology
alt_id: MT:0001466
alt_id: MT:0001467
is_a: MT:0001449 ! learning/ memory

[Term]
id: MT:0001464
name: incus size
namespace: Trait.ontology
def: "length, width, or volume of the incus" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003739 ! middle ear ossicle size
is_a: MT:0005106 ! incus morphology

[Term]
id: MT:0001465
name: malleus size
namespace: Trait.ontology
def: "length, width, or volume of the malleus" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000029 ! malleus morphology
is_a: MT:0003739 ! middle ear ossicle size

[Term]
id: MT:0001468
name: temporal memory
namespace: Trait.ontology
is_a: MT:0001449 ! learning/ memory

[Term]
id: MT:0001469
name: contextual conditioning
namespace: Trait.ontology
is_a: MT:0001468 ! temporal memory
is_a: MT:0002062 ! conditioning behavior

[Term]
id: MT:0001470
name: stapedial artery integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the small artery that passes through the ring of the stapes; while the stapedial artery is a temporary artery thought to disappear at late embryonic stage in humans, the mouse stapedial artery is complete by E13 and persists into adulthood" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0003410 ! artery integrity
is_a: MT:0005107 ! stapes morphology

[Term]
id: MT:0001485
name: pinna reflex
namespace: Trait.ontology
alt_id: MT:0001962
def: "response to an auditory stimulus by a characteristic ear twitch" [J:64900]
synonym: "ear twitch response" EXACT []
synonym: "Preyer's reflex" EXACT []
is_a: MT:0001961 ! reflex
is_a: MT:0003878 ! ear physiology

[Term]
id: MT:0001486
name: startle reflex
namespace: Trait.ontology
is_a: MT:0001961 ! reflex
is_a: MT:0003878 ! ear physiology

[Term]
id: MT:0001490
name: vibrissae reflex
namespace: Trait.ontology
alt_id: MT:0001276
alt_id: MT:0001969
is_a: MT:0001961 ! reflex

[Term]
id: MT:0001492
name: piloerection
namespace: Trait.ontology
def: "the involuntary bristling of hairs" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "goosebumps" EXACT []
is_a: MT:0001961 ! reflex

[Term]
id: MT:0001501
name: sleep pattern
namespace: Trait.ontology
alt_id: MT:0002004
synonym: "abnormal sleep pattern" EXACT []
is_a: MT:0002070 ! sleep pattern/circadian rhythm

[Term]
id: MT:0001502
name: circadian rhythm
namespace: Trait.ontology
alt_id: MT:0002005
synonym: "abnormal circadian rhythm" EXACT []
is_a: MT:0002070 ! sleep pattern/circadian rhythm

[Term]
id: MT:0001504
name: posture
namespace: Trait.ontology
is_a: MT:0002066 ! motor capabilities/coordination/movement

[Term]
id: MT:0001505
name: body posture
namespace: Trait.ontology
is_a: MT:0001504 ! posture

[Term]
id: MT:0001510
name: coat appearance
namespace: Trait.ontology
def: "coat that looks different from the usual state" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_pig
synonym: "abnormal appearance of the fur" EXACT []
is_a: MT:0000367 ! coat/ hair morphology

[Term]
id: MT:0001511
name: disheveled coat
namespace: Trait.ontology
def: "coat that looks generally unkempt" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "disheveled appearance of the fur" EXACT []
is_a: MT:0001510 ! coat appearance

[Term]
id: MT:0001513
name: response to being lifted by the tail
namespace: Trait.ontology
is_a: MT:0001961 ! reflex
is_a: MT:0003492 ! involuntary movement

[Term]
id: MT:0001515
name: grip strength
namespace: Trait.ontology
is_a: MT:0004262 ! physical strength

[Term]
id: MT:0001516
name: motor coordination/ balance
namespace: Trait.ontology
is_a: MT:0002066 ! motor capabilities/coordination/movement

[Term]
id: MT:0001522
name: swimming ability
namespace: Trait.ontology
is_a: MT:0001516 ! motor coordination/ balance
is_a: MT:0003312 ! locomotor coordination

[Term]
id: MT:0001524
name: limb coordination
namespace: Trait.ontology
is_a: MT:0001516 ! motor coordination/ balance
is_a: MT:0003312 ! locomotor coordination

[Term]
id: MT:0001525
name: balance
namespace: Trait.ontology
is_a: MT:0001516 ! motor coordination/ balance

[Term]
id: MT:0001526
name: placing response
namespace: Trait.ontology
synonym: "abnormal reaching response" EXACT []
synonym: "abnormal visual placing" EXACT []
is_a: MT:0001516 ! motor coordination/ balance

[Term]
id: MT:0001527
name: walking movement
namespace: Trait.ontology
is_a: MT:0001516 ! motor coordination/ balance
is_a: MT:0003312 ! locomotor coordination

[Term]
id: MT:0001529
name: vocalization
namespace: Trait.ontology
alt_id: MT:0001528
synonym: "Vocalization" EXACT []
is_a: MT:0002071 ! other behavior

[Term]
id: MT:0001533
name: skeleton physiology
namespace: Trait.ontology
def: "anomalous function of the bony framework of the body" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
synonym: "abnormal bone/ skeleton physiology" EXACT []
synonym: "bone/ skeletal physiology abnormalities" EXACT []
is_a: MT:0005390 ! skeleton trait

[Term]
id: MT:0001539
name: number of caudal vertebrae
namespace: Trait.ontology
def: "reduced number of the bony segments of the tail" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "decreased number of tail vertebrae" EXACT []
is_a: MT:0002759 ! caudal vertebrae morphology
relationship: part_of MT:0000138 ! vertebrae number

[Term]
id: MT:0001541
name: osteoclast physiology
namespace: Trait.ontology
def: "reduced ability or inability of osteoclasts to absorb and remove osseous tissue" [J:58795, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001533 ! skeleton physiology

[Term]
id: MT:0001542
name: bone strength
namespace: Trait.ontology
def: "change in the ability of bone to endure the application of force without yielding or breaking" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
is_a: MT:0001533 ! skeleton physiology

[Term]
id: MT:0001544
name: cardiovascular system physiology
namespace: Trait.ontology
alt_id: MT:0000302
alt_id: MT:0001623
alt_id: MT:0001626
alt_id: MT:0002130
def: "any measurable characteristic related to the function of or processes in the heart or vasculature" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
subset: slim_chkn
relationship: part_of MT:0005385 ! cardiovascular system trait

[Term]
id: MT:0001545
name: hematopoietic system physiology
namespace: Trait.ontology
def: "anomalous function of the fluid and/or its suspended elements that circulate(s) through the heart, arteries, capillaries, and veins" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal hemopoietic system physiology" EXACT []
synonym: "blood defects" EXACT []
synonym: "blood physiology abnormalities" EXACT []
is_a: MT:0005397 ! hematopoietic system trait

[Term]
id: MT:0001547
name: lipid level
namespace: Trait.ontology
def: "anomalous concentrations of fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water) in the body" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0002118 ! lipid homeostasis

[Term]
id: MT:0001553
name: circulating free fatty acids level
namespace: Trait.ontology
def: "anomalous blood concentrations of organic, monobasic acids derived from hydrocarbons and which are complexed with serum albumin for transport; they are saturated and unsaturated" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal circulating fatty acid level" EXACT []
synonym: "abnormal FFA level" EXACT []
synonym: "abnormal free fatty acids level" EXACT []
is_a: MT:0003949 ! circulating lipid level
is_a: MT:0005280 ! fatty acid level

[Term]
id: MT:0001560
name: circulating insulin level
namespace: Trait.ontology
alt_id: MT:0000191
def: "anomalous blood concentration of this polypeptide hormone, secreted by beta cells of the pancreas, that promotes glucose utilization, protein synthesis, and the formation and storage of neutral lipids" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
synonym: "abnormal insulin level" EXACT []
is_a: MT:0002078 ! glucose homeostasis

[Term]
id: MT:0001562
name: circulating calcium level
namespace: Trait.ontology
alt_id: MT:0000193
alt_id: MT:0001767
def: "anomalous concentration in the blood of this bivalent element" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal calcium level" EXACT []
is_a: MT:0000179 ! blood chemistry
is_a: MT:0004231 ! calcium ion homeostasis

[Term]
id: MT:0001565
name: circulating phosphate level
namespace: Trait.ontology
alt_id: MT:0000196
alt_id: MT:0001772
def: "anomalous blood concentrations of this salt or ester of phosphoric acid; often associated with anomalous bone mineralization " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal phosphate level" EXACT []
is_a: MT:0000179 ! blood chemistry
is_a: MT:0001765 ! ion homeostasis

[Term]
id: MT:0001569
name: circulating bilirubin level
namespace: Trait.ontology
alt_id: MT:0000200
def: "aberrant concentration in the blood of this yellow heme breakdown product " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal bilirubin level" EXACT []
is_a: MT:0000179 ! blood chemistry

[Term]
id: MT:0001570
name: circulating enzyme level
namespace: Trait.ontology
alt_id: MT:0000201
def: "aberrant concentration in the blood of any of the proteins that act as catalysts for biological reactions" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_chkn
subset: slim_pig
synonym: "abnormal blood enzyme level" EXACT []
is_a: MT:0005319 ! enzyme/ coenzyme level
is_a: MT:0005416 ! circulating protein level

[Term]
id: MT:0001573
name: circulating alanine transaminase level
namespace: Trait.ontology
alt_id: MT:0000204
def: "aberrant concentration in the blood of this enzyme, which transfers amino groups from l-alanine to 2-ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal alanine aminotransferase level" EXACT []
synonym: "abnormal alanine transaminase level" EXACT []
synonym: "abnormal ALT level" EXACT []
synonym: "abnormal glutamic-pyruvic transaminase level" EXACT []
is_a: MT:0001570 ! circulating enzyme level

[Term]
id: MT:0001574
name: oxygen level
namespace: Trait.ontology
def: "anomalous concentration of this gaseous element, essential for animal and plant life " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003948 ! gas homeostasis

[Term]
id: MT:0001575
name: cyanosis
namespace: Trait.ontology
def: "a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [J:60159, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000179 ! blood chemistry
is_a: MT:0001574 ! oxygen level

[Term]
id: MT:0001577
name: anemia
namespace: Trait.ontology
def: "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [J:53370, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002124 ! red blood cell

[Term]
id: MT:0001584
name: platelet storage pool deficiency
namespace: Trait.ontology
alt_id: MT:0000212
def: "a blood coagulation disorder in which there is a decrease or lack of platelet dense bodies" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "platelet storage pooling deficiency" EXACT []
is_a: MT:0001545 ! hematopoietic system physiology
is_a: MT:0002551 ! blood coagulation

[Term]
id: MT:0001585
name: hemolytic anemia
namespace: Trait.ontology
alt_id: MT:0000213
def: "an anemic condition resulting from an increased rate of erythrocyte destruction" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "increased rate of erythrocyte destruction" EXACT []
is_a: MT:0001577 ! anemia

[Term]
id: MT:0001586
name: erythrocyte count
namespace: Trait.ontology
alt_id: MT:0000214
def: "altered number of red blood cells per volume in the bloodstream" [J:53370]
synonym: "abnormal erythrocyte count" EXACT []
synonym: "abnormal RBC count" EXACT []
synonym: "abnormal red blood cell count" EXACT []
synonym: "erythrocyte count abnormalities" EXACT []
is_a: MT:0002124 ! red blood cell

[Term]
id: MT:0001588
name: hemoglobin
namespace: Trait.ontology
alt_id: MT:0000224
def: "defects in the levels or the function of the oxygen-carrying protein of erythrocytes" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "haemoglobin abnormalities" EXACT []
synonym: "haemoglobin defects" EXACT []
synonym: "hemoglobin defects" EXACT []
is_a: MT:0002124 ! red blood cell

[Term]
id: MT:0001589
name: mean corpuscular hemoglobin
namespace: Trait.ontology
alt_id: MT:0000225
alt_id: MT:0002595
def: "anomalies in the average levels of hemoglobin contained in an erythrocyte" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal MCH" EXACT []
synonym: "mean corpuscular hemoglobin" EXACT []
is_a: MT:0001588 ! hemoglobin

[Term]
id: MT:0001598
name: blood viscosity
namespace: Trait.ontology
alt_id: MT:0000234
def: "resistance to flow of the blood through the vessels" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition"]
is_a: MT:0002128 ! blood circulation

[Term]
id: MT:0001599
name: blood volume
namespace: Trait.ontology
alt_id: MT:0000235
def: "amount of space occupied by the blood in the vessels" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition"]
is_a: MT:0002128 ! blood circulation

[Term]
id: MT:0001601
name: myelopoiesis
namespace: Trait.ontology
alt_id: MT:0000169
def: "atypical process of bone marrow cell formation and/or bone marrow-derived blood cells" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8, tc:Teresa Chu_Mouse Genome Informatics Curator]
subset: slim_pig
synonym: "myelopoiesis abnormalities" EXACT []
is_a: MT:0005460 ! leukopoiesis

[Term]
id: MT:0001613
name: vasodilation
namespace: Trait.ontology
alt_id: MT:0000251
def: "widening of the lumen of the blood vessels" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0000249 ! blood vessel physiology

[Term]
id: MT:0001614
name: blood vessel morphology
namespace: Trait.ontology
alt_id: MT:0000252
alt_id: MT:0001611
alt_id: MT:0002125
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the network of tubes that carries blood through the body" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "vascular morphology" RELATED []
xref: MP:0001614
is_a: MT:0002127 ! cardiovascular system morphology

[Term]
id: MT:0001619
name: blood vessel permeability
namespace: Trait.ontology
alt_id: MT:0000258
def: "anomaly in the ability of the blood vessels to permit the passage of substances such as fluid, heat, or gases" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition"]
synonym: "vascular permeability" RELATED []
is_a: MT:0000249 ! blood vessel physiology

[Term]
id: MT:0001625
name: heart cell size
namespace: Trait.ontology
def: "the physical dimensions, proportions, magnitude, or extent of the cells of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "cardiac cell size" EXACT []
relationship: part_of MT:0005406 ! heart size

[Term]
id: MT:0001627
name: cardiac output
namespace: Trait.ontology
alt_id: MT:0000303
def: "blood volume pumped by each ventricle per minute (stroke volume x heart rate)" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0002128 ! blood circulation

[Term]
id: MT:0001629
name: heart rate
namespace: Trait.ontology
alt_id: MT:0000305
def: "resting heart beats per unit of time" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0001544 ! cardiovascular system physiology

[Term]
id: MT:0001636
name: heartbeat regularity
namespace: Trait.ontology
def: "timing of heart contraction" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "heart rhythm" EXACT []
is_a: MT:0004085 ! heartbeat

[Term]
id: MT:0001648
name: apoptosis
namespace: Trait.ontology
def: "excessive or absent cell death in a particular tissue or cell type" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:25248, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
xref: GO:0006915
is_a: MT:0000313 ! cell death

[Term]
id: MT:0001649
name: symphysis menti
namespace: Trait.ontology
alt_id: MT:0000096
def: "malformed fibrocartilagenous union of the two halves of the mandible (embryonic stages)" [J:17489, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal symphysis menti" EXACT []
is_a: MT:0000458 ! mandible morphology

[Term]
id: MT:0001651
name: necrosis
namespace: Trait.ontology
def: "pathological death of cells or a portion of a tissue or organ; usually due to irreversible damage" [J:23061]
is_a: MT:0000313 ! cell death

[Term]
id: MT:0001652
name: colonic necrosis
namespace: Trait.ontology
def: "pathologic death of cells within, or a portion of, the colon" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0000495 ! colon morphology

[Term]
id: MT:0001653
name: gastric necrosis
namespace: Trait.ontology
def: "pathologic death of cells within, or a portion of, the stomach" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0000470 ! stomach morphology

[Term]
id: MT:0001654
name: hepatic necrosis
namespace: Trait.ontology
def: "pathologic death of cells within, or a portion of, the liver" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "liver necrosis" EXACT []
is_a: MT:0000598 ! liver morphology

[Term]
id: MT:0001655
name: multifocal hepatic necrosis
namespace: Trait.ontology
def: "multiple localized areas of pathologic death of cells within, or portions of, the liver" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0001654 ! hepatic necrosis

[Term]
id: MT:0001656
name: focal hepatic necrosis
namespace: Trait.ontology
def: "a localized area of pathologic death of cells within, or a portion of, the liver" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0001654 ! hepatic necrosis

[Term]
id: MT:0001657
name: induced morbidity/mortality
namespace: Trait.ontology
def: "differences from the expected diseased state or death caused by an external intervention" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0005372 ! life span/aging trait

[Term]
id: MT:0001658
name: mortality induced by gamma-irradiation
namespace: Trait.ontology
def: "greater sensitivity to doses of ionizing radiation" [J:51834]
is_a: MT:0003010 ! mortality induced by ionizing radiation

[Term]
id: MT:0001661
name: life span
namespace: Trait.ontology
def: "persistence of life for a longer period than is normal for an organism" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_pig
synonym: "extended lifespan" EXACT []
is_a: MT:0005372 ! life span/aging trait

[Term]
id: MT:0001663
name: digestive system physiology
namespace: Trait.ontology
alt_id: MT:0002142
def: "altered function of the organ system that converts ingested food to nutrients and energy" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "digestive system physiology abnormalities" EXACT []
synonym: "digestive system: functional anomalies" EXACT []
xref: MGI:2173602
is_a: MT:0005381 ! digestive/alimentary trait

[Term]
id: MT:0001664
name: digestion
namespace: Trait.ontology
def: "altered ability of the mechanical, chemical, and enzymatic processes of the body to convert ingested food into material suitable for assimilation for synthesis of tissues or liberation of energy " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal digestive function" EXACT []
is_a: MT:0001663 ! digestive system physiology

[Term]
id: MT:0001665
name: chronic diarrhea
namespace: Trait.ontology
def: "prolonged diarrhea" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005036 ! diarrhea

[Term]
id: MT:0001666
name: nutrient absorption
namespace: Trait.ontology
def: "anomalous ability of the body to take in constituents of food necessary for normal physiologic function" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001663 ! digestive system physiology

[Term]
id: MT:0001667
name: carbohydrate absorption
namespace: Trait.ontology
def: "anomalous ability of the body to take in substances composed of carbon, hydrogen, and oxygen according to the general formula Cn(H2O)n; sugars and starches are examples" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0001666 ! nutrient absorption

[Term]
id: MT:0001668
name: fructose absorption
namespace: Trait.ontology
def: "anomalous ability of the body to take in this 5-carbon sugar" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0001667 ! carbohydrate absorption

[Term]
id: MT:0001669
name: glucose absorption
namespace: Trait.ontology
def: "anomalous ability of the body to take in this major monosaccharide, a 6-carbon sugar" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0001667 ! carbohydrate absorption

[Term]
id: MT:0001670
name: mineral absorption
namespace: Trait.ontology
def: "anomalous ability of the body to take in any inorganic substance that has importance in body functions" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001666 ! nutrient absorption

[Term]
id: MT:0001671
name: vitamin absorption
namespace: Trait.ontology
def: "anomalous ability to take in any of a group of organic substances, present in food, that are essential to normal metabolism" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001666 ! nutrient absorption

[Term]
id: MT:0001672
name: embryogenesis/ development
namespace: Trait.ontology
def: "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "embryogenesis/ development abnormalities" EXACT []
xref: GO:0007275
is_a: MT:0005380 ! embryogenesis trait

[Term]
id: MT:0001674
name: triploblastic development
namespace: Trait.ontology
def: "abnormal development of the three primary germ layers" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8, tc:Teresa Chu_Mouse Genome Informatics Curator]
is_a: MT:0002084 ! developmental patterning

[Term]
id: MT:0001675
name: ectoderm development
namespace: Trait.ontology
def: "failure or abnormality in the formation of the ectoderm during gastrulation" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
xref: GO:0001705
is_a: MT:0001674 ! triploblastic development

[Term]
id: MT:0001676
name: apical ectodermal ridge
namespace: Trait.ontology
def: "malformation of the multilayered ectodermal region at the tip of a limb bud necessary for the proper development of the underlying mesenchyme" [tc:Teresa Chu_Mouse Genome Informatics Curator]
is_a: MT:0001675 ! ectoderm development

[Term]
id: MT:0001680
name: mesoderm development
namespace: Trait.ontology
alt_id: MT:0001681
def: "failure or abnormality in the formation of the mesoderm during gastrulation" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal mesoderm differentiation" EXACT []
xref: GO:0001707
is_a: MT:0001674 ! triploblastic development

[Term]
id: MT:0001684
name: axial mesoderm development
namespace: Trait.ontology
def: "malformed middle primary germ layer" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:51834, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001680 ! mesoderm development

[Term]
id: MT:0001685
name: endoderm development
namespace: Trait.ontology
alt_id: MT:0001686
def: "failure or abnormality in the formation of the endoderm during gastrulation" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal endoderm differentiation" EXACT []
xref: GO:0001706
is_a: MT:0001674 ! triploblastic development

[Term]
id: MT:0001688
name: somite development
namespace: Trait.ontology
def: "anomalous formation of any of the paired, metamerically arranged cell masses formed in the embryonic paraxial mesoderm" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal metablastic segment development" EXACT []
is_a: MT:0002085 ! embryonic tissue morphology

[Term]
id: MT:0001690
name: onset of somite differentiation
namespace: Trait.ontology
def: "disorganized or absent somite tissue or somite pattern in development" [J:25248]
is_a: MT:0001688 ! somite development

[Term]
id: MT:0001691
name: somite shape
namespace: Trait.ontology
def: "atypical characteristic surface configuration of a segmental mass along the notochord of the developing embryo" [J:37888]
synonym: "irregular somite shape" EXACT []
is_a: MT:0001688 ! somite development

[Term]
id: MT:0001695
name: gastrulation
namespace: Trait.ontology
def: "anomalous development and invagination of the embryonic germ layers" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
xref: GO:0007669
is_a: MT:0002084 ! developmental patterning

[Term]
id: MT:0001697
name: embryo size
namespace: Trait.ontology
def: "anomalous proportions of embryo compared to littermates (sensu Mus: up to E14, or the completion of organogenesis)" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0001672 ! embryogenesis/ development
is_a: MT:0002088 ! embryonic growth/weight/body size

[Term]
id: MT:0001700
name: embryo turning
namespace: Trait.ontology
def: "atypical axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (Mus:E8.5-E9.5) such that the curvature of the entire trunk region is reversed and the neural ectoderm moves to the convex region and the midgut region becomes located in the concave region" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, The Atlas of Mouse Development:ISBN 0-12-402035-6]
synonym: "Abnormal Turning of Embryo" EXACT []
xref: GO:0007669
is_a: MT:0001695 ! gastrulation

[Term]
id: MT:0001704
name: dorsal-ventral axis patterning
namespace: Trait.ontology
def: "anomaly in the development or formation of the axis that runs from the front to the back surface of the body" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal back-front patterning" EXACT []
is_a: MT:0002084 ! developmental patterning

[Term]
id: MT:0001705
name: proximal-distal axis patterning
namespace: Trait.ontology
def: "anomaly in the formation or development of a body structure, often a limb, in relation to the structure's proximity to the trunk or point of origin" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002084 ! developmental patterning

[Term]
id: MT:0001706
name: left-right axis patterning
namespace: Trait.ontology
def: "anomaly in the formation or development of the body or a specific organ of the body in relation to the left and right sides of the body or organ" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002084 ! developmental patterning

[Term]
id: MT:0001710
name: amniotic fold morphology
namespace: Trait.ontology
def: "failure of amnion to form involutions" [J:40594]
synonym: "absence of amniotic folds" EXACT []
is_a: MT:0005029 ! amnion morphology

[Term]
id: MT:0001711
name: placenta morphology
namespace: Trait.ontology
def: "any anomaly in the size or shape of the organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002086 ! extraembryonic tissue morphology

[Term]
id: MT:0001712
name: placental development
namespace: Trait.ontology
def: "malformed or incomplete differentiation of the organ of metabolic exchange between the fetus and mother" [J:61790, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001711 ! placenta morphology

[Term]
id: MT:0001713
name: trophoblast giant cell number
namespace: Trait.ontology
def: "fewer than normal number of cells of the extraembryonic cell layer that contributes to the placenta" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:23171, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005033 ! trophoblast giant cell morphology

[Term]
id: MT:0001716
name: placental labyrinth morphology
namespace: Trait.ontology
def: "malformed structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [J:23171]
synonym: "abnormal labyrinth layer" RELATED []
is_a: MT:0001711 ! placenta morphology

[Term]
id: MT:0001718
name: yolk sac morphology
namespace: Trait.ontology
def: "malformed extraembryonic tissue which contributes to hematopoietic circulation" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:12623, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal exocoelomic cavity" EXACT []
is_a: MT:0002086 ! extraembryonic tissue morphology

[Term]
id: MT:0001721
name: blood island morphology
namespace: Trait.ontology
def: "missing pools of blood in the yolk sac" [J:12623]
synonym: "absence of blood islands" EXACT []
is_a: MT:0001718 ! yolk sac morphology

[Term]
id: MT:0001722
name: yolk sac color
namespace: Trait.ontology
def: "bloodless yolk sac" [J:62571]
is_a: MT:0001718 ! yolk sac morphology

[Term]
id: MT:0001723
name: yolk sac vascular plexus morphology
namespace: Trait.ontology
def: "anomaly in the pattern of the primary (honeycomb-like) vasculature of the yolk sac prior to remodeling into a mature vascular network" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0003229 ! vitelline vascular morphology

[Term]
id: MT:0001724
name: extraembryonic endoderm formation
namespace: Trait.ontology
def: "malformation of the endoderm of the extraembryonic tissue that appears prior to gastrulation and performs critical functions during embryogenesis including nutrient uptake and transport from the mother to the embryo" [J:62628]
synonym: "abnormal visceral endoderm development" EXACT []
is_a: MT:0002086 ! extraembryonic tissue morphology

[Term]
id: MT:0001725
name: umbilical cord morphology
namespace: Trait.ontology
def: "malformed connective stalk between the fetus and the placenta" [J:40203, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002086 ! extraembryonic tissue morphology

[Term]
id: MT:0001726
name: allantois morphology
namespace: Trait.ontology
def: "malformed fetal membrane which contributes to the formation of the umbilical cord and placental blood vessels" [J:12622, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002086 ! extraembryonic tissue morphology

[Term]
id: MT:0001727
name: embryo implantation
namespace: Trait.ontology
def: "failure or reduced ability of the blastocyst to attach to the endometrium of the uterus due to defects in the embryo" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001672 ! embryogenesis/ development

[Term]
id: MT:0001731
name: postnatal growth rate
namespace: Trait.ontology
def: "anomaly in reaching a developmental stage or stages after birth" [il:Ira Lu_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0002089 ! postnatal growth/weight/body size

[Term]
id: MT:0001739
name: adrenal secretion
namespace: Trait.ontology
def: "altered ability of the surparenal gland to secrete hormones " [hdene:Howard Dene_Mouse Genome Informatics Curator]
is_a: MT:0002909 ! adrenal gland physiology

[Term]
id: MT:0001740
name: adrenal epinephrine secretion
namespace: Trait.ontology
def: "inability of adrenal gland to deliver epinephrine into the blood stream" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:54931, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "failure of adrenaline secretion" EXACT []
synonym: "failure of epinephrine secretion" EXACT []
is_a: MT:0001739 ! adrenal secretion

[Term]
id: MT:0001744
name: corticosterone secretion
namespace: Trait.ontology
def: "increased release of this adrenocortical steroid that induces glycogen deposition and regulates sodium conservation and potassium secretion" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001739 ! adrenal secretion

[Term]
id: MT:0001746
name: pituitary secretion
namespace: Trait.ontology
def: "altered ability of the pituitary to release its products" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0005646 ! pituitary gland physiology

[Term]
id: MT:0001747
name: adrenocorticotropin secretion
namespace: Trait.ontology
def: "increased release of this pituitary hormone from the pituitary gland that stimulates the secretion of adrenal cortical steroids and induces growth of the adrenal cortex" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "hypersecretion of ACTH" EXACT []
is_a: MT:0001746 ! pituitary secretion

[Term]
id: MT:0001752
name: hypothalamus secretion
namespace: Trait.ontology
def: "altered ability of the hypothalamus to release its contents" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0005645 ! hypothalamus physiology

[Term]
id: MT:0001753
name: corticotropin-releasing hormone secretion
namespace: Trait.ontology
def: "excessive release of this factor, which normally stimulates the pituitary to release adrenocorticotropic hormone, from the hypothalamus" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "hypersecretion of CRH" EXACT []
is_a: MT:0001752 ! hypothalamus secretion

[Term]
id: MT:0001754
name: circulating corticotropin-releasing hormone level
namespace: Trait.ontology
def: "higher than average amount of CRH in blood; CRH is normally released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland " [J:57315]
synonym: "elevated serum levels of corticotropin-releasing hormone" EXACT []
synonym: "elevated serum levels of CRH" EXACT []
is_a: MT:0005418 ! circulating hormone level

[Term]
id: MT:0001756
name: urination
namespace: Trait.ontology
def: "anomaly in the production and excretion of urine" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal micturition" EXACT []
is_a: MT:0005502 ! urinary system physiology

[Term]
id: MT:0001757
name: urine chemistry
namespace: Trait.ontology
alt_id: MT:0005427
def: "any anomaly in the examination of urine by chemical, physical, or microscopic means" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal urinalysis" EXACT []
is_a: MT:0005428 ! clinical chemistry
is_a: MT:0005502 ! urinary system physiology

[Term]
id: MT:0001758
name: urine glucose level
namespace: Trait.ontology
def: "any change in the level of excretion of glucose in the urine" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001757 ! urine chemistry

[Term]
id: MT:0001760
name: urine enzyme level
namespace: Trait.ontology
def: "any change in the level of excretion of enzymes in the urine" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001757 ! urine chemistry

[Term]
id: MT:0001761
name: urination pattern
namespace: Trait.ontology
def: "increased or decreased frequency of urination" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001756 ! urination

[Term]
id: MT:0001762
name: polyuria
namespace: Trait.ontology
def: "increased volume of urine produced and excreted" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "diuresis" EXACT []
synonym: "frequent urination" EXACT []
synonym: "increased urine output" EXACT []
is_a: MT:0005555 ! kidney excretion

[Term]
id: MT:0001764
name: homeostasis
namespace: Trait.ontology
def: "anomaly in the state of equilibrium in the body with respect to various functions and to chemical composition of the fluids and tissues" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "homeostasis abnormalities" EXACT []
is_a: MT:0005376 ! homeostasis/metabolism trait

[Term]
id: MT:0001765
name: ion homeostasis
namespace: Trait.ontology
def: "anomaly in the state of equilibrium in the body with respect to charged molecules in the fluids and tissues" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0001764 ! homeostasis

[Term]
id: MT:0001770
name: iron level
namespace: Trait.ontology
alt_id: MT:0000209
alt_id: MT:0001581
def: "anomalous concentrations of this metallic element that normally occurs in the heme of hemoglobin, myoglobin, transferrin, ferritin, and iron-containing porphyrins; it is an essential component of enzymes such as catalase, peroxidase, and various cytochromes" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000192 ! mineral level
is_a: MT:0005637 ! iron homeostasis

[Term]
id: MT:0001771
name: circulating magnesium level
namespace: Trait.ontology
def: "anomalous blood concentration of this bioelement" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal magnesium level" EXACT []
is_a: MT:0000179 ! blood chemistry
is_a: MT:0001765 ! ion homeostasis

[Term]
id: MT:0001775
name: selenium level
namespace: Trait.ontology
def: "anomalous concentration of this essential trace element, required for glutathione peroxidase and other enzymes" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000192 ! mineral level

[Term]
id: MT:0001776
name: circulating sodium level
namespace: Trait.ontology
def: "anomalous concentration in the blood of this metallic element, the most plentiful extracellular ion in the body and the principal determinant of extracellular fluid volume" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal sodium level" EXACT []
is_a: MT:0000179 ! blood chemistry
is_a: MT:0001765 ! ion homeostasis

[Term]
id: MT:0001777
name: body temperature regulation
namespace: Trait.ontology
def: "anomalous control of the body's heat" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal temperature regulation" EXACT []
synonym: "abnormal thermoregulation" EXACT []
is_a: MT:0005535 ! body temperature

[Term]
id: MT:0001778
name: brown fat amount
namespace: Trait.ontology
alt_id: MT:0000004
synonym: "abnormal brown fat" EXACT []
is_a: MT:0002971 ! brown fat morphology
is_a: MT:0005452 ! body fat amount

[Term]
id: MT:0001781
name: white fat amount
namespace: Trait.ontology
alt_id: MT:0000007
subset: slim_cattle
subset: slim_pig
synonym: "abnormal white fat" EXACT []
is_a: MT:0002970 ! white fat morphology
is_a: MT:0005452 ! body fat amount

[Term]
id: MT:0001784
name: fluid regulation
namespace: Trait.ontology
def: "anomalous control of intracellular and/or extracellular fluid" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
is_a: MT:0001764 ! homeostasis

[Term]
id: MT:0001785
name: edema
namespace: Trait.ontology
alt_id: MT:0001338
def: "an accumulation of an excessive amount of watery fluid in cells or intercellular tissues" [J:54065, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_chkn
synonym: "oedema" EXACT []
is_a: MT:0001784 ! fluid regulation

[Term]
id: MT:0001786
name: skin edema
namespace: Trait.ontology
alt_id: MT:0001207
def: "accumulation of an excessive amount of fluid in the skin" [J:65039]
is_a: MT:0001191 ! skin condition
is_a: MT:0001785 ! edema

[Term]
id: MT:0001787
name: pericardial edema*
namespace: Trait.ontology
alt_id: MT:0000290
def: "accumulation of watery fluid in the pericardial sac of the heart" [J:52597]
subset: slim_chkn
synonym: "fluid in the heart sac" EXACT []
synonym: "pericardial edema" EXACT []
is_a: MT:0001785 ! edema

[Term]
id: MT:0001788
name: periorbital edema
namespace: Trait.ontology
alt_id: MT:0001339
def: "accumulation of an excessive amount of fluid in the area around the orbit	" [J:60896, tc:Teresa Chu_Mouse Genome Informatics Curator]
is_a: MT:0001785 ! edema
is_a: MT:0005246 ! orbit morphology

[Term]
id: MT:0001790
name: immune system physiology
namespace: Trait.ontology
alt_id: MT:0001789
def: "deviation from the normal function of the immune system" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
comment: pslim term (new)
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "Immune System" EXACT []
synonym: "immune system/response abnormalities" EXACT []
synonym: "immune system: response/ function abnormalities" EXACT []
xref: GO:0006955
is_a: MT:0005387 ! immune system trait

[Term]
id: MT:0001791
name: immunodeficiency
namespace: Trait.ontology
def: "defective immune response; can be primary due to defect in immune system or secondary due to disease" [J:61201, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001790 ! immune system physiology

[Term]
id: MT:0001793
name: susceptibility to infection
namespace: Trait.ontology
alt_id: MT:0002548
def: "a change in the likelihood that an organism will develop ill effects from a pathogenic invasion or from components of or toxins produced by pathogens" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_pig
synonym: "altered resistance to infection" EXACT []
is_a: MT:0005025 ! response to infection

[Term]
id: MT:0001798
name: macrophage phagocytosis
namespace: Trait.ontology
def: "reduced ability of these phagocytic cells to internalize particulate matter" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "decreased macrophage phagocytosis" EXACT []
is_a: MT:0002451 ! macrophage physiology
is_a: MT:0002488 ! phagocytic cell physiology

[Term]
id: MT:0001800
name: humoral immune response
namespace: Trait.ontology
def: "abnormal immune function mediated by antibodies" [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
subset: slim_chkn
subset: slim_pig
synonym: "antibody response" EXACT []
synonym: "antibody-mediated immune response abnormalities" EXACT []
synonym: "humoral immune response dysfunction" EXACT []
is_a: MT:0001790 ! immune system physiology

[Term]
id: MT:0001804
name: complement protein physiology
namespace: Trait.ontology
def: "functional anomaly of any of the complement proteins" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "complement protein dysfunction" EXACT []
is_a: MT:0002468 ! complement physiology

[Term]
id: MT:0001805
name: circulating IgG level
namespace: Trait.ontology
alt_id: MT:0001815
def: "less than normal immunoglobulin class G level" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_pig
synonym: "Decreased Serum Level of Immunoglobulin G" EXACT []
is_a: MT:0002490 ! circulating immunoglobulin concentration

[Term]
id: MT:0001806
name: circulating IgM level
namespace: Trait.ontology
alt_id: MT:0001816
def: "less than normal immunoglobulin class M level" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "Decreased Serum Level of Immunoglobulin M" EXACT []
is_a: MT:0002490 ! circulating immunoglobulin concentration

[Term]
id: MT:0001807
name: circulating IgA level
namespace: Trait.ontology
def: "less than normal immunoglobulin class A level" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002490 ! circulating immunoglobulin concentration

[Term]
id: MT:0001819
name: immune cell physiology
namespace: Trait.ontology
def: "abnormal function of the cells of the immune system" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_pig
synonym: "immune cell dysfunction" EXACT []
is_a: MT:0001790 ! immune system physiology

[Term]
id: MT:0001824
name: thymic involution
namespace: Trait.ontology
alt_id: MT:0000710
def: "premature or late decline in thymic function normally associated with advancing age" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "involuted thymus" EXACT []
is_a: MT:0003763 ! thymus physiology

[Term]
id: MT:0001828
name: T cell activation
namespace: Trait.ontology
def: "anomaly in the process of producing effector T cells from naive T cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
comment: this process requires recognition of a foreign peptide fragment bound to self-MHC and the simultaneous delivery of a co-stimulatory signal by an antigen presenting cell; it results in the clonal expansion of naive T cells and their differentiation into armed effector cells
synonym: "abnormal T-cell activation" EXACT []
is_a: MT:0002444 ! T cell physiology

[Term]
id: MT:0001830
name: activated T cell number
namespace: Trait.ontology
alt_id: MT:0000331
def: "reduced numbers of effector T cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "decreased activated T cell number" EXACT []
synonym: "decreased activated T-cell number" EXACT []
is_a: MT:0001828 ! T cell activation

[Term]
id: MT:0001831
name: T cell immunodeficiency
namespace: Trait.ontology
alt_id: MT:0002537
def: "defective immune response due to defective T-lymphocyte response" [J:33796, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "T-cell deficiency" EXACT []
synonym: "T-cell immunodeficiency" EXACT []
is_a: MT:0001791 ! immunodeficiency

[Term]
id: MT:0001835
name: antigen presentation
namespace: Trait.ontology
def: "aberration in the process by which peptide is presented to lymphocytes in a form they can recognize " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
comment: this process requires ingestion and partial digestion of the antigen followed by presentation of the digested antigen at the cell surface
synonym: "antigen presentation dysfunction" EXACT []
is_a: MT:0001790 ! immune system physiology

[Term]
id: MT:0001836
name: antigen presentation via MHC class I
namespace: Trait.ontology
def: "anomaly in the process by which peptide, bound to major histocompatibility complex class I, is presented to lymphocytes at the surface of antigen presenting cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "inability to present cytosolic antigens to Class-I restricted cytotoxic T cells" EXACT []
is_a: MT:0001835 ! antigen presentation

[Term]
id: MT:0001837
name: assembly of class I molecules
namespace: Trait.ontology
def: "impaired production of major histocompatibility complex class I molecules" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0001836 ! antigen presentation via MHC class I

[Term]
id: MT:0001838
name: intracellular transport of class I molecules
namespace: Trait.ontology
def: "impaired ability to move major histocompatibility complex class I molecules to the cell surface" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0001836 ! antigen presentation via MHC class I

[Term]
id: MT:0001839
name: level of surface class I molecules
namespace: Trait.ontology
def: "deviation from the normal concentration of major histocompatibility complex class I molecules expressed at the cell surface " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
comment: almost all nucleated blood cells express class I molecules on their surfaces (red blood cells, being non-nucleated, do not); MHC class I molecules present peptides from pathogens in the cytosol (often viruses) to CD8 T cells
is_a: MT:0001836 ! antigen presentation via MHC class I

[Term]
id: MT:0001844
name: autoimmune response
namespace: Trait.ontology
def: "condition in which cells and/or antibodies arise from and are directed against one's own tissues " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005005 ! self tolerance

[Term]
id: MT:0001845
name: inflammatory response
namespace: Trait.ontology
def: "aberrant reaction of the microcirculation characterized by movement of fluid and leukocytes from the blood into extravascular tissues" [Pathology:ISBN 0-397-51047-0]
subset: slim_pig
synonym: "inflammation" EXACT []
synonym: "inflammatory response" EXACT []
is_a: MT:0001790 ! immune system physiology

[Term]
id: MT:0001846
name: tissue specific inflammatory response
namespace: Trait.ontology
def: "greater than expected response to injury, infection, or insult" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_pig
is_a: MT:0001845 ! inflammatory response

[Term]
id: MT:0001847
name: brain inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the brain" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "encephalitis" EXACT []
is_a: MT:0006082 ! CNS inflammation

[Term]
id: MT:0001848
name: choroid inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the thin, highly vascularized membrane covering most of the posterior of the eye between the retina and the sclera" [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "choroiditis" EXACT []
is_a: MT:0001851 ! eye inflammation

[Term]
id: MT:0001849
name: susceptibility to ear inflammation
namespace: Trait.ontology
def: "prevalence of or sensitivity to local accumulation of fluid, plasma proteins and leukocytes in the ear" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
is_a: MT:0001846 ! tissue specific inflammatory response
is_a: MT:0005377 ! hearing/vestibular/ear trait

[Term]
id: MT:0001850
name: susceptibility to middle ear inflammation
namespace: Trait.ontology
alt_id: MT:0000050
def: "prevalence of or sensitivity to local accumulation of fluid, plasma proteins and leukocytes in the middle ear" [J:60896, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001849 ! susceptibility to ear inflammation

[Term]
id: MT:0001851
name: eye inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the eye" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
is_a: MT:0001846 ! tissue specific inflammatory response
is_a: MT:0005253 ! eye physiology

[Term]
id: MT:0001852
name: conjunctivitis
namespace: Trait.ontology
alt_id: MT:0001311
def: "inflammation of the mucous membrane that lines the inner surface of the eyelids and the front of the eyeball" [J:60896, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001310 ! conjunctiva morphology
is_a: MT:0001851 ! eye inflammation

[Term]
id: MT:0001853
name: heart inflammation*
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the heart" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "cardiac inflammation" EXACT []
synonym: "carditis" EXACT []
is_a: MT:0001846 ! tissue specific inflammatory response

[Term]
id: MT:0001855
name: atrial thrombosis
namespace: Trait.ontology
def: "formation or presence of a thrombus in the atria of the heart " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0005048 ! thrombosis

[Term]
id: MT:0001858
name: intestinal inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the intestine" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "g.i. inflammation" EXACT []
synonym: "gastrointestinal inflammation" EXACT []
synonym: "inflammation of intestine" EXACT []
is_a: MT:0001663 ! digestive system physiology
is_a: MT:0001846 ! tissue specific inflammatory response

[Term]
id: MT:0001859
name: kidney inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the kidney" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "nephritis" EXACT []
synonym: "renal inflammation" EXACT []
is_a: MT:0001846 ! tissue specific inflammatory response
is_a: MT:0002135 ! kidney morphology

[Term]
id: MT:0001860
name: liver inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the liver" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "hepatic inflammation" EXACT []
synonym: "hepatitis" EXACT []
is_a: MT:0000609 ! liver physiology
is_a: MT:0001846 ! tissue specific inflammatory response

[Term]
id: MT:0001861
name: lung inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the lung" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "pneumonia" EXACT []
synonym: "pulmonary inflammation" EXACT []
is_a: MT:0002405 ! respiratory system inflammation

[Term]
id: MT:0001862
name: interstitial pneumonia
namespace: Trait.ontology
def: "disorder of the lower respiratory tract, primarily affecting the alveolar wall, but may also involve the small airways and blood vessels of the lung parenchyma; this is usually inflammatory in nature" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "interstitial pneumonitis" EXACT []
is_a: MT:0001861 ! lung inflammation

[Term]
id: MT:0001863
name: vascular inflammation*
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in a blood vessel" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
comment: this is an abnormal phenotype so shouldn't be here
is_a: MT:0001846 ! tissue specific inflammatory response

[Term]
id: MT:0001865
name: striated muscle inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the striated muscle" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
is_a: MT:0001846 ! tissue specific inflammatory response
is_a: MT:0002106 ! muscle physiology

[Term]
id: MT:0001866
name: nasal inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the proximal portion of the respiratory passages" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
subset: slim_pig
is_a: MT:0002405 ! respiratory system inflammation

[Term]
id: MT:0001867
name: rhinitis
namespace: Trait.ontology
alt_id: MT:0001113
def: "inflammation of the mucous membrane of the nose" [J:60896, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8, tc:Teresa Chu_Mouse Genome Informatics Curator]
subset: slim_pig
synonym: "nasal catarrh" EXACT []
is_a: MT:0001866 ! nasal inflammation
is_a: MT:0002238 ! nasal mucosa morphology

[Term]
id: MT:0001868
name: ovary inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the ovary" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "oophoritis" EXACT []
synonym: "ovarian inflammation" EXACT []
is_a: MT:0002254 ! reproductive system inflammation
is_a: MT:0003699 ! female reproductive system physiology

[Term]
id: MT:0001869
name: pancreas inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the pancreas " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "pancreatic inflammation" EXACT []
synonym: "pancreatitis" EXACT []
is_a: MT:0001846 ! tissue specific inflammatory response
is_a: MT:0002693 ! pancreas physiology

[Term]
id: MT:0001870
name: salivary gland inflammation
namespace: Trait.ontology
alt_id: MT:0000625
alt_id: MT:0000626
alt_id: MT:001871
def: "local accumulation of fluid, plasma proteins, and leukocytes in the salivary gland" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "increased inflammatory response of the salivary glands" EXACT []
synonym: "sialadenitis" EXACT []
synonym: "sialoadenitis" EXACT []
is_a: MT:0001846 ! tissue specific inflammatory response
is_a: MT:0005310 ! salivary gland physiology

[Term]
id: MT:0001872
name: sinus inflammation
namespace: Trait.ontology
def: "increase in susceptibility of the hollow cavities in bone (usually but not exclusively those in the skull) to allergens and/or pathogens" [J:60896, tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "sinusitis" EXACT []
is_a: MT:0002405 ! respiratory system inflammation

[Term]
id: MT:0001873
name: stomach inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the stomach" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "autoimmune gastritis" EXACT []
is_a: MT:0001663 ! digestive system physiology
is_a: MT:0001846 ! tissue specific inflammatory response

[Term]
id: MT:0001874
name: spinous layer cell number
namespace: Trait.ontology
def: "diffuse hyperplasia of the spinous layer of the skin" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001236 ! spinous layer morphology

[Term]
id: MT:0001875
name: testis inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the testis" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "orchitis" EXACT []
synonym: "testicular inflammation" EXACT []
is_a: MT:0002254 ! reproductive system inflammation
is_a: MT:0003698 ! male reproductive system physiology

[Term]
id: MT:0001878
name: allergic response
namespace: Trait.ontology
def: "hypersensitivity caused by exposure to a specific antigen (allergen) resulting in a marked increase in reactivity to that antigen upon subsequent exposure" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002531 ! type I hypersensitivity reaction

[Term]
id: MT:0001879
name: lymphatic vessel morphology
namespace: Trait.ontology
alt_id: MT:0000309
alt_id: MT:0001638
alt_id: MT:0001639
def: "malformation of the network of vessels which carries lymph around the body" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8, tc:Teresa Chu_Mouse Genome Informatics Curator]
synonym: "lymphatic system abnormalities" EXACT []
is_a: MT:0000685 ! immune system morphology

[Term]
id: MT:0001881
name: mammary gland physiology
namespace: Trait.ontology
def: "aberrant function of the milk-secreting gland that lies within the breast" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_pig
synonym: "abnormal mammary gland function" EXACT []
synonym: "mammary gland abnormalities" EXACT []
is_a: MT:0002164 ! gland physiology
is_a: MT:0003699 ! female reproductive system physiology

[Term]
id: MT:0001882
name: lactation
namespace: Trait.ontology
alt_id: MT:0001383
def: "atypical production of milk from the mammary gland" [J:51296]
subset: slim_cattle
subset: slim_pig
synonym: "lactation abnormalities" EXACT []
synonym: "lactation defects" EXACT []
is_a: MT:0001881 ! mammary gland physiology

[Term]
id: MT:0001883
name: mammary adenocarcinoma
namespace: Trait.ontology
alt_id: MT:0002011
def: "higher than normal incidence of malignant tumors of the mammary gland" [J:62919]
is_a: MT:0002038 ! carcinoma

[Term]
id: MT:0001884
name: mammary alveoli morphology
namespace: Trait.ontology
def: "increased size due to increased cellularity of the sac-like structure of the mammary gland that secretes milk after pregnancy" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000627 ! mammary gland morphology

[Term]
id: MT:0001885
name: mammary duct morphology
namespace: Trait.ontology
def: "increased size due to increased cellularity of the tubular structure running from the nipple to the alveoli clusters in the mammary gland" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000627 ! mammary gland morphology

[Term]
id: MT:0001890
name: anencephaly
namespace: Trait.ontology
alt_id: MT:0000915
def: "absence of the bones of the cranial vault and absent or rudimentary cerebral and cerebellar hemispheres, brainstem, and basal ganglia" [J:31571, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000074 ! neurocranium morphology
is_a: MT:0000913 ! brain development

[Term]
id: MT:0001891
name: hydroencephaly
namespace: Trait.ontology
alt_id: MT:0000916
def: "excessive accumulation of cerebrospinal fluid in the brain, especially the cerebral ventricles, often leading to increased brain size and other brain trauma" [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "hydrocephalus" EXACT []
synonym: "Hydrocephaly" EXACT []
is_a: MT:0000254 ! cerebrospinal fluid volume
is_a: MT:0000913 ! brain development
is_a: MT:0002200 ! brain ventricle/choroid plexus morphology

[Term]
id: MT:0001893
name: non-obstructive hydrocephaly
namespace: Trait.ontology
alt_id: MT:0000918
def: "abnormal cerebrospinal fluid absorption where there is no obstruction to fluid flow in the ventricular system" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "Communicating Hydrocephalus" EXACT []
synonym: "communicating hydrocephaly" EXACT []
is_a: MT:0001891 ! hydroencephaly

[Term]
id: MT:0001895
name: hippocampus function
namespace: Trait.ontology
def: "anomalous activity of the deep lying structure of the cerebrum involved with memory storage" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0001898
name: long term depression
namespace: Trait.ontology
alt_id: MT:0001474
def: "change from the normal, persistent activity-dependent decrease in synaptic efficacy between neurons, often following slow, weak stimulation of neurons" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Principles of Neural Science:ISBN 0-8385-8034-3]
synonym: "abnormal LTD" EXACT []
is_a: MT:0002915 ! synaptic depression

[Term]
id: MT:0001900
name: synaptic plasticity
namespace: Trait.ontology
def: "decreased or inability of the nervous system to change its reactivity as a result of successive activations " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0001901
name: absence of NMDA -mediated synaptic currents
namespace: Trait.ontology
def: "absence of a measured amplitude or response to stimulation of NMDA receptors" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "absence of NMDA -mediated synaptic currents: CA1 region" EXACT []
is_a: MT:0002888 ! NMDA-mediated synaptic currents

[Term]
id: MT:0001905
name: dopamine level
namespace: Trait.ontology
def: "greater or less than the normal concentration of this catecholamine neurotransmitter, derived from tyrosine and the precursor to norepinephrine and epinephrine" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal dopaminergic levels" EXACT []
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0001907
name: cerebellar function
namespace: Trait.ontology
def: "anomalous activity of the portion of the brain in the back of the head between the cerebrum and the pons that controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0001908
name: somatosensory cortex function
namespace: Trait.ontology
def: "anomalous activity of the area of the parietal lobe concerned with receiving general sensations" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0001907 ! cerebellar function

[Term]
id: MT:0001909
name: NMDA receptor mediated synaptic activity in barrel cortex
namespace: Trait.ontology
def: "lower than normal levels of excitatory synaptic current in the barrel cortex" [J:64064, Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
is_a: MT:0001908 ! somatosensory cortex function
is_a: MT:0002888 ! NMDA-mediated synaptic currents

[Term]
id: MT:0001911
name: cerebrospinal fluid production
namespace: Trait.ontology
def: "change in the normal secretion of the fluid that fills the ventricles and other cavities of the brain and spinal cord" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0001915
name: intracranial hemorrhage
namespace: Trait.ontology
def: "bleeding within the skull, including hemorrhage into the brain and within the cranial epidural, subdural, and subarachnoid spaces" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "intracranial bleeding" EXACT []
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0001916
name: intracerebral hemorrhage
namespace: Trait.ontology
def: "bleeding within the cerebrum" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "cerebral hemorrhage" EXACT []
synonym: "intracerebral bleeding" EXACT []
is_a: MT:0001915 ! intracranial hemorrhage

[Term]
id: MT:0001919
name: reproductive system physiology
namespace: Trait.ontology
def: "anomaly in the function of the organs associated with producing offspring" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "reproductive system physiology anomalies" EXACT []
is_a: MT:0005389 ! reproductive system trait

[Term]
id: MT:0001921
name: fertility
namespace: Trait.ontology
alt_id: MT:0001372
def: "diminished ability to produce live offspring" [J:65030]
subset: slim_cattle
subset: slim_pig
synonym: "decreased fecundity" EXACT []
synonym: "semi-sterile" EXACT []
synonym: "semisterile" EXACT []
is_a: MT:0002161 ! fertility/fecundity

[Term]
id: MT:0001922
name: male fertility
namespace: Trait.ontology
def: "reduced ability of male to produce live offspring" [J:61340, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001921 ! fertility
is_a: MT:0003698 ! male reproductive system physiology

[Term]
id: MT:0001923
name: female fertility
namespace: Trait.ontology
def: "reduced ability of female to produce live offspring" [J:60409, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001921 ! fertility
is_a: MT:0003699 ! female reproductive system physiology

[Term]
id: MT:0001927
name: oestrous cycle (sensu Rodentia)
namespace: Trait.ontology
def: "failure of or aberrant timing of the sexual cycle of female animals" [J:34193, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_pig
synonym: "abnormal estrous cycle" EXACT []
synonym: "abnormal estrus cycle" EXACT []
is_a: MT:0003699 ! female reproductive system physiology

[Term]
id: MT:0001928
name: ovulation
namespace: Trait.ontology
def: "aberration in the release of an ovum from a rupturing Graafian follicle, normally regulated by a surge in luteinizing hormone" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_pig
is_a: MT:0001927 ! oestrous cycle (sensu Rodentia)
is_a: MT:0003375 ! menstrual cycle (sensu H. sapiens)

[Term]
id: MT:0001929
name: gametogenesis
namespace: Trait.ontology
def: "defective formation or differentiation of germ cells" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:42324, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0002160 ! reproductive system morphology

[Term]
id: MT:0001930
name: meiosis
namespace: Trait.ontology
def: "malfunction in the process of nuclear division that results in gametes with one half the normal number of the original cell" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001929 ! gametogenesis

[Term]
id: MT:0001931
name: oogenesis
namespace: Trait.ontology
def: "atypical formation or failure to form the female germ cells" [J:35782, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001929 ! gametogenesis

[Term]
id: MT:0001932
name: spermiogenesis
namespace: Trait.ontology
def: "failure of sperm cells to form or differentiate" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001156 ! spermatogenesis

[Term]
id: MT:0001933
name: litter size
namespace: Trait.ontology
def: "deviation from the normal number of live born pups in a litter" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002161 ! fertility/fecundity

[Term]
id: MT:0001937
name: sexual maturation
namespace: Trait.ontology
def: "a delay or a block in the development of the sexual organs at a given age" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0002212 ! secondary sex determination

[Term]
id: MT:0001938
name: time of sexual maturation
namespace: Trait.ontology
def: "immaturity of the sexual organs at a given age" [J:61190]
synonym: "delayed onset of sexual maturity" EXACT []
synonym: "delayed sexual maturity" EXACT []
is_a: MT:0001937 ! sexual maturation

[Term]
id: MT:0001939
name: secondary sex reversal
namespace: Trait.ontology
def: "secondary sexual phenotype is not consistent with the chromosomal sex, i.e., internal and/or external genitalia are inconsistent with chromosomal sex " [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0002212 ! secondary sex determination
is_a: MT:0005652 ! sex reversal

[Term]
id: MT:0001940
name: testicular cell number
namespace: Trait.ontology
def: "decreased cell number in the testicles" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001148 ! testes size

[Term]
id: MT:0001942
name: lung volume
namespace: Trait.ontology
def: "anomaly in the amount of air that the lungs contain at various points of the respiratory cycle" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal lung volume measurements" EXACT []
is_a: MT:0001943 ! respiration

[Term]
id: MT:0001943
name: respiration
namespace: Trait.ontology
def: "anomaly in the movement of gases into and out of the lung " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002133 ! respiratory system physiology

[Term]
id: MT:0001944
name: pancreas morphology
namespace: Trait.ontology
def: "malformation of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [il:Ira Lu_Mouse Genome Informatics Curator]
synonym: "abnormal pancreas" EXACT []
is_a: MT:0000462 ! digestive system morphology
is_a: MT:0002163 ! gland morphology

[Term]
id: MT:0001945
name: bronchoconstriction
namespace: Trait.ontology
def: "reduction in the caliber of the bronchus or bronchi" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002314 ! respiratory mechanics

[Term]
id: MT:0001947
name: mucociliary clearance
namespace: Trait.ontology
def: "anomaly in the rate of ciliary and secretory activity of the respiratory submucosal glands" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002314 ! respiratory mechanics

[Term]
id: MT:0001948
name: vesicoureteral reflux
namespace: Trait.ontology
def: "the retrograde flow of urine from the bladder into the ureters and kidneys" [J:77653, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "VUX" EXACT []
is_a: MT:0002136 ! kidney physiology

[Term]
id: MT:0001949
name: respiratory dead space
namespace: Trait.ontology
def: "anomaly in the section of the respiratory tract that does not exchange oxygen and carbon dioxide with pulmonary capillary blood" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002314 ! respiratory mechanics

[Term]
id: MT:0001950
name: respiratory sounds
namespace: Trait.ontology
def: "anomalous noises heard over any part of the respiratory tract" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002315 ! respiratory signs/symptoms

[Term]
id: MT:0001951
name: breathing
namespace: Trait.ontology
alt_id: MT:0001955
def: "irregular or atypical breathing pattern	" [J:17489, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "irregular breathing" EXACT []
is_a: MT:0002315 ! respiratory signs/symptoms

[Term]
id: MT:0001953
name: respiratory failure
namespace: Trait.ontology
def: "cessation of or failure to commence breathing" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:60159]
is_a: MT:0001943 ! respiration

[Term]
id: MT:0001954
name: respiratory distress
namespace: Trait.ontology
def: "physical difficulty or inability to breathe" [J:54931, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002315 ! respiratory signs/symptoms

[Term]
id: MT:0001956
name: breathing depth
namespace: Trait.ontology
def: "breathing that is shallower and/or slower than normal" [J:64289, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001951 ! breathing

[Term]
id: MT:0001957
name: apnea
namespace: Trait.ontology
def: "absence of breathing; sometimes episodic" [J:17384, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "failure to breathe" EXACT []
is_a: MT:0001951 ! breathing

[Term]
id: MT:0001958
name: emphysema
namespace: Trait.ontology
def: "lung disease characterized by increased size of terminal bronchioles with destructive changes in their walls and reduction in number" [J:33629, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002133 ! respiratory system physiology

[Term]
id: MT:0001961
name: reflex
namespace: Trait.ontology
alt_id: MT:0001476
synonym: "reflexes" EXACT []
is_a: MT:0002067 ! sensory capabilities/reflexes/nociception

[Term]
id: MT:0001963
name: hearing
namespace: Trait.ontology
alt_id: MT:0001960
def: "the ability to receive auditory stimuli" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal auditory perception" EXACT []
synonym: "auditory abnormalities" EXACT []
synonym: "auditory defects" EXACT []
xref: GO:0007605
is_a: MT:0002104 ! hearing physiology

[Term]
id: MT:0001964
name: auditory threshold
namespace: Trait.ontology
def: "anomalies in the average point at which one may first detect auditory signals at given frequencies" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
xref: GO:0007605
is_a: MT:0001963 ! hearing

[Term]
id: MT:0001968
name: touch/ nociception
namespace: Trait.ontology
is_a: MT:0002067 ! sensory capabilities/reflexes/nociception
is_a: MT:0005392 ! touch/vibrissae trait

[Term]
id: MT:0001970
name: pain threshold
namespace: Trait.ontology
is_a: MT:0001968 ! touch/ nociception

[Term]
id: MT:0001983
name: olfactory system physiology
namespace: Trait.ontology
alt_id: MT:0001110
alt_id: MT:0001111
def: "abnormal function of the system relating to smell " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "olfactory abnormalities" EXACT []
synonym: "olfactory defects" EXACT []
synonym: "olfactory system abnormalities" EXACT []
is_a: MT:0005394 ! taste/olfaction trait

[Term]
id: MT:0001984
name: olfaction
namespace: Trait.ontology
def: "change in the ability to smell" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001983 ! olfactory system physiology

[Term]
id: MT:0001985
name: gustatory system physiology
namespace: Trait.ontology
def: "anomalous perception of taste" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal taste physiology" EXACT []
synonym: "abnormal taste response" EXACT []
is_a: MT:0005394 ! taste/olfaction trait

[Term]
id: MT:0001986
name: taste sensitivity
namespace: Trait.ontology
def: "changes in the ability to perceive a particular flavor or suggestion of something imparting a flavor by the chemoreceptors of the gustatory system" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001985 ! gustatory system physiology

[Term]
id: MT:0001992
name: vestibuloocular reflex
namespace: Trait.ontology
alt_id: MT:0001477
is_a: MT:0000353 ! vestibular system physiology
is_a: MT:0001961 ! reflex
is_a: MT:0005253 ! eye physiology

[Term]
id: MT:0001993
name: blinking reflex
namespace: Trait.ontology
alt_id: MT:0001478
is_a: MT:0001961 ! reflex

[Term]
id: MT:0001995
name: blinking frequency
namespace: Trait.ontology
alt_id: MT:0001480
is_a: MT:0001993 ! blinking reflex

[Term]
id: MT:0001999
name: photosensitivity
namespace: Trait.ontology
alt_id: MT:0001484
def: "alterations in the response to sunlight or UV irradiation, especially sensitivity of the eyes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "photosensitivity abnormalities" EXACT []
is_a: MT:0002121 ! metabolism
is_a: MT:0005253 ! eye physiology

[Term]
id: MT:0002001
name: blindness
namespace: Trait.ontology
def: "loss of the sense of sight" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002090 ! vision

[Term]
id: MT:0002006
name: tumorigenesis
namespace: Trait.ontology
def: "induction of new growth" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000001 ! Trait

[Term]
id: MT:0002009
name: preneoplasia
namespace: Trait.ontology
def: "state preceding the pathological process resulting in a neoplasm; does not necessarily imply cancerous development" [J:47225]
is_a: MT:0002166 ! tumor susceptibility

[Term]
id: MT:0002012
name: trichofolliculoma
namespace: Trait.ontology
def: "tumors which contain multiple abortive and/or misaligned hair follicles " [J:51296]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0002013
name: pilomatriculoma
namespace: Trait.ontology
def: "hair follicle tumor" [J:51296]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0002014
name: papilloma
namespace: Trait.ontology
def: "benign epithelial tumor" [J:47225]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0002015
name: epithelioid cysts
namespace: Trait.ontology
def: "abnormal membranous sacs appearing in an epithelium" [J:51296]
is_a: MT:0001191 ! skin condition
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0002016
name: ovarian cysts
namespace: Trait.ontology
def: "cystic ovary; usually refers to a benign growth" [J:35782, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "cystic ovary" EXACT []
synonym: "dermoid cysts" EXACT []
is_a: MT:0001126 ! ovary morphology

[Term]
id: MT:0002017
name: spontaneous tumor
namespace: Trait.ontology
def: "higher than normal incidence of tumors with unknown cause" [J:44427]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0002018
name: malignant tumors
namespace: Trait.ontology
def: "higher than normal incidence of locally invasive, destructive and metastatic tumors " [J:44427, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0002019
name: tumor incidence
namespace: Trait.ontology
def: "deviation from the expected number of abnormal growths of a specific tissue in a specific population" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002166 ! tumor susceptibility

[Term]
id: MT:0002021
name: susceptibility to induced tumors
namespace: Trait.ontology
def: "higher than normal frequency of tumor incidence induced by a carcinogen or mutagen" [J:44427]
is_a: MT:0005514 ! susceptibility to tumor development

[Term]
id: MT:0002022
name: lymphoma
namespace: Trait.ontology
def: "neoplasm of any lymphoid tissue" [J:18542, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "lymphoid tumor" EXACT []
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0002023
name: B cell derived lymphoma
namespace: Trait.ontology
def: "heterogeneous lymphoid tumors generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "B-cell derived lymphoma" EXACT []
is_a: MT:0002022 ! lymphoma

[Term]
id: MT:0002024
name: T cell derived lymphoma
namespace: Trait.ontology
def: "group of heterogeneous lymphoid tumors representing malignant transformations of T-lymphocytes" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "T-cell derived lymphoma" EXACT []
is_a: MT:0002022 ! lymphoma

[Term]
id: MT:0002025
name: B cell/T cell derived lymphoma
namespace: Trait.ontology
def: "group of heterogeneous lymphoid tumors representing malignant transformations of both B-lymphocytes and T-lymphocytes" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "B cell/T cell derived lymphoma" EXACT []
synonym: "B-cell/T-cell derived lymphoma" EXACT []
is_a: MT:0002022 ! lymphoma

[Term]
id: MT:0002026
name: leukemia
namespace: Trait.ontology
def: "progressive proliferation of abnormal leukocytes in hematopoietic tissues, organs and blood" [J:18542, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0002027
name: lung adenocarcinoma
namespace: Trait.ontology
def: "malignant neoplasm of epithelial cells in the lung" [J:18542, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002038 ! carcinoma

[Term]
id: MT:0002028
name: hepatoma
namespace: Trait.ontology
def: "malignant tumor composed of neoplastic liver cells" [J:18542, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "hepatocarcinoma" EXACT []
synonym: "hepatocellular carcinoma" EXACT []
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0002029
name: fibrosarcoma
namespace: Trait.ontology
def: "malignant neoplasm derived from deep fibrous tissue" [J:18542, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002032 ! sarcoma

[Term]
id: MT:0002030
name: neurofibrosarcoma
namespace: Trait.ontology
def: "malignant neoplasm of fibrous tissue of the nervous system" [J:18542, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002032 ! sarcoma

[Term]
id: MT:0002031
name: adrenal tumor
namespace: Trait.ontology
def: "tumors of the adrenal gland, including phaeochomocytomas" [J:18542, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0002032
name: sarcoma
namespace: Trait.ontology
def: "connective tissue neoplasm associated with the proliferation of mesodermal cells" [J:58877, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0002033
name: malignant triton tumors
namespace: Trait.ontology
def: " malignant tumor with neurogenic and myogenic differentiation; usually arises in tissues of neural crest origin" [J:58877, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "MTTs" EXACT []
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0002034
name: malignant peripheral nerve sheath tumors
namespace: Trait.ontology
def: "a highly aggressive tumor arising from the connective tissue surrounding peripheral nerves " [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "malignant neurolemmoma" RELATED []
synonym: "MPNSTs" EXACT []
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0002035
name: leiomyosarcoma
namespace: Trait.ontology
def: "malignant tumor derived from smooth (nonstriated) muscle" [J:58877, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002032 ! sarcoma

[Term]
id: MT:0002036
name: rhabdomyosarcoma
namespace: Trait.ontology
def: "malignant tumor derived from skeletal (striated) muscle" [J:58877, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002032 ! sarcoma

[Term]
id: MT:0002037
name: fibrohistocytoma
namespace: Trait.ontology
def: "slowly growing skin nodule derived from cellular fibrous tissue; often surrounds capillaries" [J:58877, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "dermatofibroma" EXACT []
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0002038
name: carcinoma
namespace: Trait.ontology
def: "malignant neoplasm arising from epithelial cells, usually glandular or squamous" [J:58877, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0002039
name: neuroblastoma
namespace: Trait.ontology
def: "malignant neoplasm characterized by immature nerve cells of embryonic type" [J:58877, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0002041
name: pituitary adenoma
namespace: Trait.ontology
def: "appearance of benign neoplasms of the pituitary" [J:33042, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002815 ! adenoma

[Term]
id: MT:0002043
name: colonic hamartoma
namespace: Trait.ontology
def: "tumor-like focal abnormalities of the intestines; rarely neoplastic" [J:47050]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0002044
name: colonic adenoma
namespace: Trait.ontology
def: "benign tumors of the large intestine" [J:38772]
synonym: "colonic adenomata" EXACT []
is_a: MT:0002404 ! intestinal adenoma

[Term]
id: MT:0002045
name: renal cystadenoma
namespace: Trait.ontology
def: "benign cystic neoplasm of the kidney derived from glandular epithelium origin" [J:57631, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002815 ! adenoma

[Term]
id: MT:0002046
name: renal carcinoma
namespace: Trait.ontology
def: "malignant neoplasm of the kidney" [J:57631, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002038 ! carcinoma

[Term]
id: MT:0002047
name: hepatic hemangioma
namespace: Trait.ontology
def: "neoplastic- like masses in the liver; often undergoes spontaneous regression" [J:57631, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "liver angioma" EXACT []
is_a: MT:0002947 ! hemangioma

[Term]
id: MT:0002048
name: lung adenoma
namespace: Trait.ontology
def: "benign epithelial neoplasm of the lung" [J:57631, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002815 ! adenoma

[Term]
id: MT:0002049
name: extremity angiosarcoma
namespace: Trait.ontology
def: "malignant neoplasm of soft tissues; thought to arise from endothelial cells of blood vessels" [J:57631, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003667 ! hemangiosarcoma

[Term]
id: MT:0002050
name: pheochromocytoma
namespace: Trait.ontology
def: "a benign neoplasm derived from adrenal medullary cells; usually associated with hypertension" [J:63229, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002031 ! adrenal tumor

[Term]
id: MT:0002051
name: skin papilloma
namespace: Trait.ontology
def: "a circumscribed, benign epithelial tumor projecting from the surrounding surface" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002014 ! papilloma
is_a: MT:0005276 ! skin tumor

[Term]
id: MT:0002059
name: seminal gland morphology
namespace: Trait.ontology
alt_id: MT:0000656
def: "anomalous structure of one of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal seminal gland" EXACT []
synonym: "abnormal seminal vesicles" EXACT []
is_a: MT:0000653 ! sex gland morphology
is_a: MT:0001145 ! male reproductive anatomy

[Term]
id: MT:0002060
name: skin morphology
namespace: Trait.ontology
def: "malformation or atypical structure of the membranous protective covering of the body" [J:56777, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
subset: slim_pig
synonym: "abnormal cutis" EXACT []
synonym: "abnormal skin anatomy" EXACT []
is_a: MT:0002096 ! skin condition/ morphology

[Term]
id: MT:0002062
name: conditioning behavior
namespace: Trait.ontology
xref: MGI:2173567
is_a: MT:0002063 ! learning/memory/conditioning

[Term]
id: MT:0002063
name: learning/memory/conditioning
namespace: Trait.ontology
subset: slim_pig
xref: MGI:2173568
is_a: MT:0005386 ! behavior/neurological trait

[Term]
id: MT:0002064
name: seizures
namespace: Trait.ontology
alt_id: MT:0000946
alt_id: MT:0001493
def: "sudden and often acute manifestation of epileptic attack, sometimes convulsive" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "neurological/behavioral: seizures/epilepsy" EXACT []
synonym: "seizures/epilepsy" EXACT []
xref: MGI:2173569
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0002066
name: motor capabilities/coordination/movement
namespace: Trait.ontology
subset: slim_pig
xref: MGI:2173571
is_a: MT:0005386 ! behavior/neurological trait

[Term]
id: MT:0002067
name: sensory capabilities/reflexes/nociception
namespace: Trait.ontology
is_a: MT:0005386 ! behavior/neurological trait

[Term]
id: MT:0002068
name: parental behavior
namespace: Trait.ontology
def: "altered behavior of animals towards offspring" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "neurological/behavioral: parental behavior anomalies" EXACT []
xref: MGI:2173573
is_a: MT:0002557 ! social/conspecific interaction

[Term]
id: MT:0002069
name: eating/drinking behavior
namespace: Trait.ontology
comment: pslim term
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
xref: MGI:2173574
is_a: MT:0005386 ! behavior/neurological trait

[Term]
id: MT:0002070
name: sleep pattern/circadian rhythm
namespace: Trait.ontology
comment: pslim term
is_a: MT:0005386 ! behavior/neurological trait

[Term]
id: MT:0002071
name: other behavior
namespace: Trait.ontology
synonym: "neurological/behavioral: other anomalies" EXACT []
is_a: MT:0005386 ! behavior/neurological trait

[Term]
id: MT:0002073
name: hair growth
namespace: Trait.ontology
alt_id: MT:0000409
def: "absence or reduced amount of hair or abnormal onset of hair growth cycle or development" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
subset: slim_pig
synonym: "coat: hair growth defects" EXACT []
synonym: "hair growth abnormalities" EXACT []
xref: MGI:2173539
is_a: MT:0000367 ! coat/ hair morphology

[Term]
id: MT:0002074
name: hair texture
namespace: Trait.ontology
alt_id: MT:0002077
def: "irregular or unusual appearance of the structure of the hair" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "coat: hair texture defects" EXACT []
synonym: "hair texture abnormalities" EXACT []
xref: MGI:2173540
is_a: MT:0000367 ! coat/ hair morphology

[Term]
id: MT:0002075
name: coat color
namespace: Trait.ontology
alt_id: MT:0000368
def: "irregular or unusual pigmentation of the hair in relation to control animals" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
subset: slim_cattle
subset: slim_pig
synonym: "coat: color anomalies" EXACT []
xref: MGI:2173541
is_a: MT:0000367 ! coat/ hair morphology
is_a: MT:0001186 ! pigmentation trait

[Term]
id: MT:0002076
name: hair follicle structure/orientation
namespace: Trait.ontology
def: "malformation or misalignment of the epidermis from which the hair shaft develops" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "coat: hair follicle structure/orientation anomalies" EXACT []
xref: MGI:2173542
is_a: MT:0000367 ! coat/ hair morphology

[Term]
id: MT:0002078
name: glucose homeostasis
namespace: Trait.ontology
def: "anomaly in the state of equilibrium or processing in the body with respect to glucose in the fluids and tissues" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
subset: slim_chkn
subset: slim_pig
synonym: "abnormal glucose metabolism" EXACT []
synonym: "metabolism: abnormal glucose homeostasis" EXACT []
xref: MGI:2173579
is_a: MT:0001764 ! homeostasis

[Term]
id: MT:0002084
name: developmental patterning
namespace: Trait.ontology
alt_id: MT:0001702
def: "abnormal systematic arrangement of the developing body along an axis" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: phenoslim term
synonym: "embryogenesis: developmental patterning abnormalities" EXACT []
xref: MGI:2173529
is_a: MT:0001672 ! embryogenesis/ development

[Term]
id: MT:0002085
name: embryonic tissue morphology
namespace: Trait.ontology
alt_id: MT:0001673
def: "structural abnormality or development of any embryonic tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: phenoslim term
synonym: "abnormal embryogenesis" EXACT []
synonym: "embryogenesis: embryonic tissue dysmorphology" EXACT []
xref: MGI:2173530
is_a: MT:0001672 ! embryogenesis/ development

[Term]
id: MT:0002086
name: extraembryonic tissue morphology
namespace: Trait.ontology
alt_id: MT:0001708
alt_id: MT:0001709
def: "structural abnormality or development of the membranes involved with embryonic protection and nutrition" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:40594, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
comment: Phenoslim term
synonym: "abnormal extraembryonic tissues" EXACT []
synonym: "embryogenesis: extraembryonic tissue dysmorphology" EXACT []
xref: MGI:2173531
is_a: MT:0001672 ! embryogenesis/ development

[Term]
id: MT:0002088
name: embryonic growth/weight/body size
namespace: Trait.ontology
def: "limited or accelerated growth or development apparent during the embryonic period (sensu Mus: up to E14, or the completion of organogenesis)" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: Phenoslim term
synonym: "growth/weight/body size abnormality: embryonic" EXACT []
xref: MGI:2173533
is_a: MT:0004196 ! prenatal growth/weight/body size

[Term]
id: MT:0002089
name: postnatal growth/weight/body size
namespace: Trait.ontology
alt_id: MT:0001252
def: "increased or decreased average body size, weight or growth characteristic abnormalities manifesting after birth" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: phenoslim term
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "abnormal trunk/ body shape" EXACT []
synonym: "growth/weight/body size abnormality: postnatal" EXACT []
synonym: "trunk/ body shape abnormalities" EXACT []
xref: GO:0040007
xref: GO:0040014
xref: MGI:2173534
is_a: MT:0005378 ! growth/size trait

[Term]
id: MT:0002090
name: vision
namespace: Trait.ontology
alt_id: MT:0001991
alt_id: MT:0002000
def: "inability or decreased ability to see" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: phenoslim term
synonym: "abnormal visual ability" EXACT []
synonym: "eye: visual defects" EXACT []
synonym: "visual defects" EXACT []
xref: MGI:2173535
is_a: MT:0005253 ! eye physiology

[Term]
id: MT:0002092
name: eye morphology
namespace: Trait.ontology
alt_id: MT:0001285
alt_id: MT:0001294
alt_id: MT:0001295
def: "abnormal development of the eye tissues resulting in morphological abnormality or abnormal structure of the visual system" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: phenoslim term
synonym: "abnormal eyes" EXACT []
synonym: "eye abnormalities" EXACT []
synonym: "eye malformation" EXACT []
synonym: "eye tissue abnormalities" EXACT []
synonym: "eye: dysmorphology" EXACT []
synonym: "visual system abnormalities" EXACT []
synonym: "visual system defects" EXACT []
xref: GO:0001654
xref: MGI:2173536
is_a: MT:0005391 ! vision/eye trait

[Term]
id: MT:0002093
name: cornea/lens morphology
namespace: Trait.ontology
def: "any dysmorphology or complete or partial opacity of the lens or cornea" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: phenoslim term
synonym: "eye: corneal/lens defect" EXACT []
xref: MGI:2173537
is_a: MT:0005193 ! anterior eye segment morphology

[Term]
id: MT:0002095
name: skin pigmentation
namespace: Trait.ontology
alt_id: MT:0001187
def: "variation of skin color or complexion" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "skin: pigmentation anomalies" EXACT []
xref: MGI:2173544
is_a: MT:0001186 ! pigmentation trait
is_a: MT:0002096 ! skin condition/ morphology

[Term]
id: MT:0002096
name: skin condition/ morphology
namespace: Trait.ontology
alt_id: MT:0001185
def: "malformed or atypical condition of the skin" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
subset: slim_chkn
subset: slim_pig
synonym: "abnormal skin" EXACT []
synonym: "skin abnormalities" EXACT []
synonym: "skin: texture/condition anomalies" EXACT []
xref: MGI:2173545
is_a: MT:0005393 ! skin/coat/nails/feathers trait

[Term]
id: MT:0002098
name: vibrissae morphology
namespace: Trait.ontology
alt_id: MT:0001271
def: "irregular or unusual structure, appearance, or alignment of the vibrissae" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "abnormal vibrissae" EXACT []
synonym: "abnormal whiskers" EXACT []
synonym: "vibrissae abnormalities" EXACT []
synonym: "vibrissae defects" EXACT []
synonym: "vibrissae: dysmorphology" EXACT []
xref: MGI:2173547
is_a: MT:0005392 ! touch/vibrissae trait

[Term]
id: MT:0002100
name: tooth morphology
namespace: Trait.ontology
alt_id: MT:0000115
alt_id: MT:0000123
def: "atypical size, shape or hard tissue structure of the teeth " [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "abnormal teeth" EXACT []
synonym: "abnormal tooth" EXACT []
synonym: "Abnormal Tooth Structure" EXACT []
synonym: "teeth abnormalities" EXACT []
synonym: "teeth: tooth dysmorphology" EXACT []
xref: MGI:2173553
is_a: MT:0002116 ! craniofacial bone morphology

[Term]
id: MT:0002102
name: ear morphology
namespace: Trait.ontology
alt_id: MT:0000014
alt_id: MT:0000016
def: "form, structure or development of any of the parts of the ear or vestibular system" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "auditory/ vestibular system abnormalities" EXACT []
synonym: "auditory/ vestibular system morphology" EXACT []
synonym: "ear development/ ear formation" EXACT []
synonym: "ears: dysmorphology" EXACT []
xref: GO:0042471
xref: MGI:2173556
is_a: MT:0005377 ! hearing/vestibular/ear trait

[Term]
id: MT:0002104
name: hearing physiology
namespace: Trait.ontology
def: "processes involved in the perception of sound" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "auditory perception" EXACT []
synonym: "auditory physiology" RELATED []
xref: GO:0007605
xref: MGI:2173555
is_a: MT:0003878 ! ear physiology

[Term]
id: MT:0002106
name: muscle physiology
namespace: Trait.ontology
alt_id: MT:0002105
def: "anomalous function of the muscle, not due to an anatomical defect" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: former pslim term
subset: slim_chkn
subset: slim_pig
synonym: "muscle physiology abnormalities" EXACT []
synonym: "musculature: physiological defects" EXACT []
xref: MGI:2173559
is_a: MT:0005369 ! muscle trait

[Term]
id: MT:0002108
name: muscle morphology
namespace: Trait.ontology
alt_id: MT:0000728
alt_id: MT:0000758
def: "abnormal development of muscle tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "abnormal muscle" EXACT []
synonym: "abnormal musculature" EXACT []
synonym: "muscle abnormalities" EXACT []
synonym: "musculature abnormalities" EXACT []
synonym: "musculature: muscle dysmorphology" EXACT []
xref: MGI:2173558
is_a: MT:0005369 ! muscle trait

[Term]
id: MT:0002109
name: limb morphology
namespace: Trait.ontology
alt_id: MT:0000546
def: "form, structure, or number of limbs" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "abnormal limb" EXACT []
synonym: "extremities: limb dysmorphology" EXACT []
synonym: "limb abnormalities" EXACT []
xref: MGI:2173549
is_a: MT:0000545 ! limbs/digits/tail morphology

[Term]
id: MT:0002110
name: digit morphology
namespace: Trait.ontology
alt_id: MT:0000560
def: "abnormal development of the digits resulting in structural abnormality" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "abnormal digit" EXACT []
synonym: "digit abnormalities" EXACT []
synonym: "extremities: digit dysmorphology" EXACT []
xref: MGI:2173550
is_a: MT:0004271 ! paw/hand/foot/hoof morphology

[Term]
id: MT:0002111
name: tail morphology
namespace: Trait.ontology
alt_id: MT:0000584
alt_id: MT:0005173
def: "abnormal development of the tail resulting in structural abnormality" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "abnormal tail" EXACT []
synonym: "abnormal tail structure" EXACT []
synonym: "extremities: tail dysmorphology" EXACT []
synonym: "tail abnormalities" EXACT []
synonym: "tail structure abnormalities" EXACT []
xref: MGI:2173551
is_a: MT:0000545 ! limbs/digits/tail morphology

[Term]
id: MT:0002113
name: skeleton development
namespace: Trait.ontology
alt_id: MT:0000056
alt_id: MT:0001534
alt_id: MT:0001537
def: "anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "abnormal bone development" EXACT []
synonym: "abnormal bone formation/ structure" EXACT []
synonym: "abnormal skeletogenesis" EXACT []
synonym: "skeletal: osteogenesis/developmental anomalies" EXACT []
xref: MGI:2173561
is_a: MT:0005508 ! skeleton morphology

[Term]
id: MT:0002114
name: axial skeleton morphology
namespace: Trait.ontology
def: "abnormal development of vertebral, spinal or sternal bones resulting in morphological abnormality" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
subset: slim_cattle
subset: slim_pig
synonym: "skeletal: axial defects" EXACT []
xref: MGI:2173562
is_a: MT:0005508 ! skeleton morphology

[Term]
id: MT:0002115
name: skeleton extremities morphology
namespace: Trait.ontology
def: "abnormal development of limb, foot or tail bones resulting in morphological abnormality" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
subset: slim_chkn
subset: slim_pig
synonym: "skeletal: extremities defects" EXACT []
xref: MGI:2173563
is_a: MT:0000545 ! limbs/digits/tail morphology
is_a: MT:0005508 ! skeleton morphology

[Term]
id: MT:0002116
name: craniofacial bone morphology
namespace: Trait.ontology
alt_id: MT:0000072
def: "abnormal development of cranial or facial bones resulting in morphological abnormality" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "cranial/facial bone defect" EXACT []
synonym: "craniofacial bone defects" EXACT []
synonym: "skeletal: craniofacial defects" EXACT []
xref: MGI:2173564
is_a: MT:0000428 ! craniofacial morphology
is_a: MT:0005508 ! skeleton morphology

[Term]
id: MT:0002118
name: lipid homeostasis
namespace: Trait.ontology
def: "anomaly in the state of equilibrium in the body with respect to lipids in the fluids and tissues" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "metabolism: abnormal lipid homeostasis" EXACT []
xref: MGI:2173578
is_a: MT:0001764 ! homeostasis

[Term]
id: MT:0002121
name: metabolism
namespace: Trait.ontology
alt_id: MT:0002120
def: "altered chemical and physical processes of the body or of a tissue, not due to lipid or glucose chemistry" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
subset: slim_chkn
subset: slim_pig
synonym: "metabolism: other metabolic defect" EXACT []
synonym: "metabolism: other metabolic defect measured by clinical chemistry" EXACT []
xref: MGI:2173580
xref: MGI:2173581
is_a: MT:0005376 ! homeostasis/metabolism trait

[Term]
id: MT:0002123
name: hematopoiesis
namespace: Trait.ontology
alt_id: MT:0000236
alt_id: MT:0000241
alt_id: MT:0001600
alt_id: MT:0001604
alt_id: MT:0001605
alt_id: MT:0002402
def: "abnormal development of the enucleated fetal and adult erythrocytes that develop in the aorta, genital ridge and mesonephros region and later in the fetal and adult liver" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "abnormal blood development" EXACT []
synonym: "abnormal definitive hematopoiesis" EXACT []
synonym: "abnormal hematogenesis" EXACT []
synonym: "abnormal hematosis" EXACT []
synonym: "abnormal hemogenesis" EXACT []
synonym: "abnormal hemopoiesis" EXACT []
synonym: "abnormal sanguification" EXACT []
synonym: "blood development abnormalities" EXACT []
synonym: "deregulated hematopoiesis" EXACT []
synonym: "hematology: hematopoietic anomalies" EXACT []
synonym: "hematopoiesis abnormalities" EXACT []
synonym: "myeloid stem cell abnormalities" EXACT []
xref: MGI:2173583
is_a: MT:0002429 ! blood cell morphology/development

[Term]
id: MT:0002124
name: red blood cell
namespace: Trait.ontology
def: "anomaly in the structure or maintenance of erythrocytes or oxygen-transporting material in the blood" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
subset: slim_cattle
subset: slim_chkn
synonym: "abnormal erythrocyte" EXACT []
synonym: "hematology: abnormal red blood cell count/anemia" EXACT []
xref: MGI:2173584
is_a: MT:0000245 ! erythropoiesis

[Term]
id: MT:0002127
name: cardiovascular system morphology
namespace: Trait.ontology
alt_id: MT:0000177
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the heart or vasculature" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
subset: slim_chkn
subset: slim_pig
relationship: part_of MT:0005385 ! cardiovascular system trait

[Term]
id: MT:0002128
name: blood circulation
namespace: Trait.ontology
alt_id: MT:0000308
alt_id: MT:0001632
def: "any measurable characteristic of the flow of blood within the body" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
comment: pslim term
xref: MGI:2173588
is_a: MT:0001544 ! cardiovascular system physiology

[Term]
id: MT:0002132
name: respiratory system morphology
namespace: Trait.ontology
alt_id: MT:0001174
def: "anomalous structure of pulmonary tissues" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "respiratory system abnormalities" EXACT []
synonym: "respiratory system: dysmorphology" EXACT []
xref: MGI:2173592
is_a: MT:0005388 ! respiratory system trait

[Term]
id: MT:0002133
name: respiratory system physiology
namespace: Trait.ontology
def: "anomalous function of the pulmonary system; inability or reduced ability to intake and exchange oxygen and carbon dioxide with the environment" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
subset: slim_pig
synonym: "abnormal respiratory function" EXACT []
synonym: "respiratory system dysfunction" EXACT []
synonym: "respiratory system physiology abnormalities" EXACT []
synonym: "respiratory system: respiratory distress/failure/functional anomalies" EXACT []
xref: MGI:2173593
is_a: MT:0005388 ! respiratory system trait

[Term]
id: MT:0002135
name: kidney morphology
namespace: Trait.ontology
alt_id: MT:0000518
def: "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "abnormal kidney" EXACT []
synonym: "abnormal renal morphology" EXACT []
synonym: "kidney abnormalities" EXACT []
synonym: "kidney/renal system: dysmorphology" EXACT []
xref: MGI:2173595
is_a: MT:0000516 ! urinary system morphology

[Term]
id: MT:0002136
name: kidney physiology
namespace: Trait.ontology
def: "altered ability or inability to excrete urine, not due to anatomical defect" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "abnormal kidney function" EXACT []
synonym: "kidney/renal system: functional anomalies" EXACT []
xref: MGI:2173596
is_a: MT:0005502 ! urinary system physiology

[Term]
id: MT:0002138
name: liver/biliary system morphology
namespace: Trait.ontology
alt_id: MT:0002172
def: "structural abnormality or aberrant development of any of the tissues of the liver or biliary system" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
subset: slim_chkn
subset: slim_pig
synonym: "hepatic system abnormalities" EXACT []
synonym: "hepatic system defects" EXACT []
synonym: "liver/hepatic system: dysmorphology" EXACT []
xref: MGI:2173598
is_a: MT:0005370 ! liver/biliary system trait

[Term]
id: MT:0002139
name: liver/biliary system physiology
namespace: Trait.ontology
alt_id: MT:0002173
def: "altered function of the liver not due to anatomical defect" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "abnormal hepatic system physiology" EXACT []
synonym: "hepatic system physiology abnormalities" EXACT []
synonym: "liver/hepatic system: functional anomalies" EXACT []
xref: MGI:2173599
is_a: MT:0005370 ! liver/biliary system trait

[Term]
id: MT:0002144
name: B lymphocyte development
namespace: Trait.ontology
alt_id: MT:0001801
alt_id: MT:0001803
alt_id: MT:0002438
def: "atypical production of or inability to produce mature B cells, and/or accumulation of B cell precursors" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "abnormal B cell development" EXACT []
synonym: "abnormal B cell maturation" EXACT []
synonym: "abnormal B cell morphology/development" EXACT []
synonym: "abnormal B lymphocyte maturation" EXACT []
synonym: "abnormal B-cell development" EXACT []
synonym: "abnormal B-cell maturation" EXACT []
synonym: "abnormal lymphoid development/ B lymphocyte defects" EXACT []
synonym: "B cell abnormalities" EXACT []
synonym: "B lymphocyte abnormalities" EXACT []
synonym: "B-cell abnormalities" EXACT []
synonym: "immune system: lymphoid development/ B lymphocyte defects" EXACT []
xref: MGI:2173604
is_a: MT:0002401 ! lymphopoiesis
is_a: MT:0002619 ! lymphocyte morphology/development

[Term]
id: MT:0002145
name: T lymphocyte development
namespace: Trait.ontology
alt_id: MT:0001821
alt_id: MT:0001822
alt_id: MT:0002431
alt_id: MT:0002489
def: "atypical production of or inability to produce mature T cells, and/or accumulation of T cell precursors" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "abnormal lymphoid development/ T lymphocyte defects" EXACT []
synonym: "abnormal T cell development" EXACT []
synonym: "abnormal T cell maturation" EXACT []
synonym: "abnormal T cell morphology/development" EXACT []
synonym: "abnormal T-cell development" EXACT []
synonym: "abnormal T-cell maturation" EXACT []
synonym: "abnormal thymocyte development" EXACT []
synonym: "immune system: lymphoid development/ T lymphocyte defects" EXACT []
synonym: "T lymphocyte abnormalities" EXACT []
synonym: "T-cell abnormalities" EXACT []
xref: MGI:2173605
is_a: MT:0002401 ! lymphopoiesis
is_a: MT:0002619 ! lymphocyte morphology/development

[Term]
id: MT:0002148
name: immune system: hypersensitivity
namespace: Trait.ontology
def: "immune response that results in tissue injury" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "immunologically mediated tissue injury" EXACT []
xref: MGI:2173608
is_a: MT:0001790 ! immune system physiology

[Term]
id: MT:0002151
name: neural tube morphology/development
namespace: Trait.ontology
alt_id: MT:0000922
def: "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "abnormal neural tube" EXACT []
synonym: "abnormal neural tube morphology" EXACT []
synonym: "central nervous system: neural tube defects" EXACT []
synonym: "neural tube defects" EXACT []
xref: GO:0007420
xref: MGI:2173611
is_a: MT:0003861 ! nervous system development

[Term]
id: MT:0002152
name: brain morphology
namespace: Trait.ontology
alt_id: MT:0000770
alt_id: MT:0000775
def: "anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk]
comment: pslim term
synonym: "abnormal brain" EXACT []
synonym: "abnormal brain structure" EXACT []
synonym: "brain abnormalities" EXACT []
synonym: "brain structure abnormalities" EXACT []
synonym: "central nervous system: brain dysmorphology" EXACT []
xref: MGI:2173612
is_a: MT:0003632 ! nervous system morphology

[Term]
id: MT:0002160
name: reproductive system morphology
namespace: Trait.ontology
alt_id: MT:0001114
alt_id: MT:0001115
def: "structural or developmental anomaly of any of the tissues involved in the reproductive system" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "abnormal reproductive anatomy" EXACT []
synonym: "abnormal reproductive system" EXACT []
synonym: "reproductive system abnormalities" EXACT []
synonym: "reproductive system defects" EXACT []
synonym: "reproductive system: dysmorphology" EXACT []
xref: MGI:2173620
is_a: MT:0005389 ! reproductive system trait

[Term]
id: MT:0002161
name: fertility/fecundity
namespace: Trait.ontology
alt_id: MT:0001920
def: "reduced ability or inability to produce live offspring" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "abnormal fecundity" EXACT []
synonym: "reproductive system: fertility/fecundity anomalies" EXACT []
xref: MGI:2173621
is_a: MT:0001919 ! reproductive system physiology

[Term]
id: MT:0002163
name: gland morphology
namespace: Trait.ontology
alt_id: MT:0000594
def: "abnormal development of any glandular tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
subset: slim_cattle
subset: slim_pig
synonym: "abnormal glands" EXACT []
synonym: "gland abnormalities" EXACT []
synonym: "glands: dysmorphology" EXACT []
xref: MGI:2173623
is_a: MT:0005379 ! endocrine/exocrine gland trait

[Term]
id: MT:0002164
name: gland physiology
namespace: Trait.ontology
alt_id: MT:0001733
alt_id: MT:0001738
alt_id: MT:0002692
def: "altered glandular secretion not due to anatomical defect" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
subset: slim_cattle
subset: slim_pig
synonym: "abnormal endocrine gland function" EXACT []
synonym: "abnormal endocrine system physiology" EXACT []
synonym: "abnormal gland function" EXACT []
synonym: "endocrine system physiology abnormalities" EXACT []
synonym: "gland function abnormalities" EXACT []
synonym: "glands: functional anomalies" EXACT []
xref: MGI:2173624
is_a: MT:0005379 ! endocrine/exocrine gland trait

[Term]
id: MT:0002166
name: tumor susceptibility
namespace: Trait.ontology
def: "greater than or less than the average number of tumors, usually a specific type, arising in a given strain when compared to controls" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "tumorigenesis: altered tumor susceptibility/resistance" EXACT []
xref: MGI:2173626
is_a: MT:0002006 ! tumorigenesis

[Term]
id: MT:0002174
name: gastrulation movements
namespace: Trait.ontology
def: "failure of embryonic cells to migrate, or migrate to the appropriate target during the development and invagination of the primary germ layers" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:52418]
xref: GO:0007669
is_a: MT:0001695 ! gastrulation

[Term]
id: MT:0002176
name: brain weight
namespace: Trait.ontology
def: "greater than average weight of the brain" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000771 ! brain size

[Term]
id: MT:0002177
name: outer ear morphology
namespace: Trait.ontology
def: "malformation or malfunction of any components of the auricles or external acoustic meatus" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal pinna morphology" EXACT []
is_a: MT:0002102 ! ear morphology

[Term]
id: MT:0002181
name: brain cell morphology
namespace: Trait.ontology
def: "any malformation or malfunction of any or all brain cell types" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal brain cells" EXACT []
synonym: "brain cell abnormalities" EXACT []
is_a: MT:0002152 ! brain morphology

[Term]
id: MT:0002182
name: astrocyte morphology
namespace: Trait.ontology
def: "anomalous structure, number or composition of one of the large neuroglia cells of nervous tissue" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal astrocytes" EXACT []
synonym: "abnormal astroglia" EXACT []
is_a: MT:0000952 ! CNS glia morphology

[Term]
id: MT:0002183
name: gliosis
namespace: Trait.ontology
def: "increased growth pattern of neuroglia in a damaged area of the brain or spinal cord" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002182 ! astrocyte morphology

[Term]
id: MT:0002184
name: innervation
namespace: Trait.ontology
def: "the malformation, misprojection or malfunction of the connection of nerve fibers with a target" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal axonal projection" EXACT []
synonym: "abnormal neuronal projection" EXACT []
synonym: "innervation abnormalities" EXACT []
is_a: MT:0003632 ! nervous system morphology

[Term]
id: MT:0002185
name: ectopia
namespace: Trait.ontology
alt_id: MT:0002186
def: "congenital positional anomaly or displacement of any part of the body or organ" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "heterotopia" EXACT []
is_a: MT:0005395 ! other trait

[Term]
id: MT:0002187
name: fibula morphology
namespace: Trait.ontology
def: "malformation of the lateral and smaller bone of the lower limb" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal fibula" EXACT []
is_a: MT:0003723 ! long bone morphology

[Term]
id: MT:0002189
name: heart muscle trabeculae integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the supporting bundles of muscular fibers lining the walls of the heart" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "cardiac muscle trabeculae integrity" RELATED []
synonym: "myocardial trabeculae integrity" RELATED []
relationship: part_of MT:0000062 ! heart muscle trabeculae morphology
relationship: part_of MT:0000073 ! heart muscle integrity

[Term]
id: MT:0002191
name: artery morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the blood vessels that carry blood away from the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
xref: MP:0002191
is_a: MT:0001614 ! blood vessel morphology

[Term]
id: MT:0002192
name: hydrops fetalis
namespace: Trait.ontology
def: "an abnormal accumulation of serous fluid in fetal tissues" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
synonym: "fetal edema" EXACT []
is_a: MT:0001785 ! edema

[Term]
id: MT:0002198
name: skin pigmentation pattern
namespace: Trait.ontology
def: "arrangement of pigmented and/or unpigmented patches of skin" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002095 ! skin pigmentation

[Term]
id: MT:0002199
name: brain commissure morphology
namespace: Trait.ontology
def: "absent or defective structure in a bundle of nerve fibers connecting the two brain hemispheres" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal brain commissure" EXACT []
synonym: "abnormal commissure" EXACT []
is_a: MT:0002152 ! brain morphology

[Term]
id: MT:0002200
name: brain ventricle/choroid plexus morphology
namespace: Trait.ontology
def: "malformation or absence of the brain ventricles or their associated choroid plexuses" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
comment: suggested from TGMC
synonym: "abnormal brain ventricle/choroid plexus" EXACT []
synonym: "abnormal choroid/ventricle" EXACT []
is_a: MT:0002152 ! brain morphology

[Term]
id: MT:0002204
name: neurotransmitter level
namespace: Trait.ontology
def: "aberrant concentration of endogenous signaling molecules secreted by neurons that alter the behavior of neurons or effector cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "neurotransmitter abnormalities" EXACT []
is_a: MT:0003635 ! synaptic transmission

[Term]
id: MT:0002206
name: CNS synaptic transmission
namespace: Trait.ontology
def: "defect in the communication from a neuron to a target across a synapse in the central nervous system" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal CNS neurotransmission" EXACT []
synonym: "abnormal synaptic transmission" EXACT []
is_a: MT:0003635 ! synaptic transmission

[Term]
id: MT:0002207
name: long term potentiation
namespace: Trait.ontology
alt_id: MT:0001472
alt_id: MT:0001896
alt_id: MT:0001897
alt_id: MT:0002154
def: "alterations in a persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal LTP" EXACT []
synonym: "abnormal LTP: CA1 region" EXACT []
synonym: "abnormal LTP: CA3 region" EXACT []
synonym: "central nervous system: LTP anomalies" EXACT []
synonym: "long term potentiation abnormalities" EXACT []
xref: MGI:2173614
is_a: MT:0002206 ! CNS synaptic transmission

[Term]
id: MT:0002208
name: germ cell morphology
namespace: Trait.ontology
def: "anomalous structure of the germ cell, that is, any of the reproductive (generative) cells of a multicellular organism, whether they are undifferentiated or fully differentiated" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal gamete morphology" EXACT []
is_a: MT:0001929 ! gametogenesis

[Term]
id: MT:0002209
name: germ cell number
namespace: Trait.ontology
def: "reduced numbers of any of the reproductive (generative) cells of a multicellular organism, whether they are undifferentiated or fully differentiated" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001929 ! gametogenesis

[Term]
id: MT:0002210
name: sex determination
namespace: Trait.ontology
alt_id: MT:0001936
def: "anomaly of primary or secondary sexual development or characteristics" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "abnormal reproductive system development" EXACT []
synonym: "abnormal sexual differentiation" EXACT []
is_a: MT:0002160 ! reproductive system morphology

[Term]
id: MT:0002211
name: primary sex determination
namespace: Trait.ontology
def: "aberrant gonadal development resulting in either abnormal or absent gonads or the development of gonads inconsistent with the chromosomal sex" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, llw2:Linda Washburn_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_pig
synonym: "abnormal gonad development" EXACT []
is_a: MT:0002210 ! sex determination

[Term]
id: MT:0002212
name: secondary sex determination
namespace: Trait.ontology
def: "gonadal development may or may not be normal, and the phenotype of the animal outside the gonad does not match chromosomal sex or is ambiguous" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0002210 ! sex determination

[Term]
id: MT:0002213
name: true hermaphroditism
namespace: Trait.ontology
def: "having both ovarian and testicular tissue present" [llw2:Linda Washburn_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002211 ! primary sex determination

[Term]
id: MT:0002214
name: streak gonad
namespace: Trait.ontology
def: "impairment of genital ridge development; aplasia of gonadal tissue which is sometimes replaced with functionless tissue" [llw2:Linda Washburn_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "gonadal streak" EXACT []
is_a: MT:0002211 ! primary sex determination
is_a: MT:0003936 ! reproductive system development

[Term]
id: MT:0002216
name: seminiferous tubule morphology
namespace: Trait.ontology
def: "malformation of the tubules in the testes where spermatogenesis occurs" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal seminiferous tubules" EXACT []
is_a: MT:0001146 ! testis morphology

[Term]
id: MT:0002221
name: lymph organ size
namespace: Trait.ontology
def: "change in the normal size of lymphatic tissues" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_chkn
is_a: MT:0002722 ! immune system organ morphology

[Term]
id: MT:0002222
name: lymph organ cellularity
namespace: Trait.ontology
def: "change in the normal number of cells within a lymph organ" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002722 ! immune system organ morphology

[Term]
id: MT:0002224
name: spleen size
namespace: Trait.ontology
def: "deviation from the normal spleen size" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_chkn
is_a: MT:0000689 ! spleen morphology
is_a: MT:0002221 ! lymph organ size

[Term]
id: MT:0002225
name: spleen cellularity
namespace: Trait.ontology
def: "anomaly in the cellular makeup of the spleen" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "spleen cellularity abnormalities" EXACT []
is_a: MT:0000689 ! spleen morphology
is_a: MT:0002222 ! lymph organ cellularity

[Term]
id: MT:0002227
name: spleen capsule morphology
namespace: Trait.ontology
def: "anomalous structure of the connective tissue that surrounds the spleen" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0000689 ! spleen morphology

[Term]
id: MT:0002228
name: spleen trabecular vein morphology
namespace: Trait.ontology
def: "anomalous structure of one of the veins that feed the splenic vein" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology:ISBN 0-397-51047-0]
is_a: MT:0000689 ! spleen morphology

[Term]
id: MT:0002229
name: neural integrity
namespace: Trait.ontology
def: "a retrogressive impairment of function or destruction of neural tissue" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "neuronal degeneration" EXACT []
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0002230
name: primitive streak formation
namespace: Trait.ontology
def: "anomaly in the establishment of the midline ridge of embryonic epiblast that later develops into mesoderm and endoderm" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, The Atlas of Mouse Development:ISBN 0-12-402035-6]
is_a: MT:0002231 ! primitive streak morphology

[Term]
id: MT:0002231
name: primitive streak morphology
namespace: Trait.ontology
def: "anomaly in the midline ridge of the embryonic epiblast that later develops into mesoderm and endoderm" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, The Atlas of Mouse Development:ISBN 0-12-402035-6]
synonym: "defective primitive streak" EXACT []
is_a: MT:0002084 ! developmental patterning

[Term]
id: MT:0002233
name: nose morphology
namespace: Trait.ontology
def: "any structural anomaly of the organ that is specialized for smell and is part of the respiratory system" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_pig
synonym: "abnormal nose" EXACT []
is_a: MT:0002132 ! respiratory system morphology

[Term]
id: MT:0002234
name: pharynx morphology
namespace: Trait.ontology
def: "structural anomaly in the passage between the mouth and the posterior nares and the larynx and esophagus" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal pharynx" EXACT []
is_a: MT:0002132 ! respiratory system morphology

[Term]
id: MT:0002235
name: external nares morphology
namespace: Trait.ontology
def: "any structural anomaly of the anterior opening to the nasal cavity" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal anterior nares" EXACT []
synonym: "abnormal external nares" EXACT []
synonym: "abnormal nostril" EXACT []
is_a: MT:0002233 ! nose morphology

[Term]
id: MT:0002236
name: internal nares morphology
namespace: Trait.ontology
def: "any structural anomaly of the portion of the opening of the nasal cavity into the nasal pharynx " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal choanae" EXACT []
synonym: "abnormal internal nares" EXACT []
synonym: "abnormal posterior nares" EXACT []
is_a: MT:0002233 ! nose morphology

[Term]
id: MT:0002237
name: nasal cavity morphology
namespace: Trait.ontology
def: "any structural anomaly of the portion of the respiratory tract that extends from the nares to the pharynx; the nasal cavity is lined with ciliated mucosa" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal nasal cavity" EXACT []
is_a: MT:0002233 ! nose morphology

[Term]
id: MT:0002238
name: nasal mucosa morphology
namespace: Trait.ontology
alt_id: MT:0001112
def: "any structural anomaly of the mucous membrane that lines the nasal cavity" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_pig
synonym: "abnormal nasal epithelium" EXACT []
synonym: "abnormal nasal mucosa" EXACT []
synonym: "abnormal nasal mucous membrane" EXACT []
is_a: MT:0002233 ! nose morphology
is_a: MT:0002277 ! respiratory mucosa morphology

[Term]
id: MT:0002239
name: nasal septum morphology
namespace: Trait.ontology
def: "any structural anomaly of the structure that separates the two nasal cavities" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal nasal septum" EXACT []
is_a: MT:0002233 ! nose morphology

[Term]
id: MT:0002240
name: paranasal sinus morphology
namespace: Trait.ontology
def: "any structural anomaly of these extensions of the nasal cavity" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal paranasal sinuses" EXACT []
is_a: MT:0002233 ! nose morphology

[Term]
id: MT:0002241
name: laryngeal mucosa goblet cell morphology
namespace: Trait.ontology
def: "any structural anomaly of the epithelial cells lining the larynx, which produce mucins" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings, Pathology_2nd edition:ISBN 0-397-51047-0]
synonym: "abnormal goblet cells of the laryngeal mucosa" EXACT []
is_a: MT:0002261 ! laryngeal mucosa morphology

[Term]
id: MT:0002242
name: olfactory mucosa morphology
namespace: Trait.ontology
def: "any structural anomaly of the portion of the nasal mucosa that contains the olfactory sensory endings" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal olfactory epithelium" EXACT []
synonym: "abnormal olfactory mucosa" EXACT []
is_a: MT:0002238 ! nasal mucosa morphology

[Term]
id: MT:0002243
name: vomeronasal organ morphology
namespace: Trait.ontology
def: "any structural anomaly of the specialized portion of the nasal septum that is composed of chemosensitive cells and lies anteriorly in the nasal cavity" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
comment: this organ is believed to function in sensing pheromones
synonym: "abnormal vomeronasal organ" EXACT []
is_a: MT:0002239 ! nasal septum morphology
is_a: MT:0005499 ! olfactory system morphology

[Term]
id: MT:0002244
name: turbinate morphology
namespace: Trait.ontology
def: "any structural anomaly of the small curved bones that extends horizontally along the lateral wall of the nasal passage" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal nasal concha" EXACT []
synonym: "abnormal turbinates" EXACT []
is_a: MT:0002233 ! nose morphology
is_a: MT:0005274 ! viscerocranium morphology

[Term]
id: MT:0002245
name: ethmoid sinus morphology
namespace: Trait.ontology
def: "any structural anomaly of these small spaces found within the ethmoid bone" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal ethmoid sinus" EXACT []
is_a: MT:0002240 ! paranasal sinus morphology

[Term]
id: MT:0002246
name: frontal sinus morphology
namespace: Trait.ontology
def: "any structural anomaly of these paired air spaces within the frontal bone" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal frontal sinus" EXACT []
is_a: MT:0002240 ! paranasal sinus morphology

[Term]
id: MT:0002247
name: maxillary sinus morphology
namespace: Trait.ontology
def: "any structural anomaly of the air space located within the maxilla, and which opens to the middle meatus of the nasal cavity" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal maxillary sinus" EXACT []
is_a: MT:0002240 ! paranasal sinus morphology

[Term]
id: MT:0002248
name: sphenoid sinus morphology
namespace: Trait.ontology
def: "any structural anomaly of the air space located within the sphenoid bone, and which opens to the highest meatus of the nasal cavity" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal sphenoid sinus" EXACT []
is_a: MT:0002240 ! paranasal sinus morphology

[Term]
id: MT:0002249
name: larynx morphology
namespace: Trait.ontology
def: "any structural anomaly of the most superior portion of the respiratory tract" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology_2nd edition:ISBN 0-397-51047-0]
comment: the larynx is specialized for vocalization and is bounded above by the pharynx and oral cavity, and below byt the first tracheal ring
is_a: MT:0002132 ! respiratory system morphology

[Term]
id: MT:0002250
name: hypopharynx morphology
namespace: Trait.ontology
def: "structural anomaly in the portion of the pharynx that lies below the upper edge of the epiglottis and opens into the larynx and the esophagus" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "hypopharynx abnormalities" EXACT []
is_a: MT:0002234 ! pharynx morphology

[Term]
id: MT:0002251
name: nasopharynx morphology
namespace: Trait.ontology
def: "structural anomaly of the section of the pharynx that lies above the soft palate" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "nasopharynx abnormalities" EXACT []
is_a: MT:0002234 ! pharynx morphology

[Term]
id: MT:0002252
name: oropharynx morphology
namespace: Trait.ontology
def: "structural anomaly of the portion of the pharynx that lies between the soft palate and the upper edge of the epiglottis" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002234 ! pharynx morphology

[Term]
id: MT:0002253
name: pharyngeal muscle morphology
namespace: Trait.ontology
def: "structural anomaly of any of the muscles of the pharynx, the inferior, middle and superior constrictors, salpingopharyngeus, and stylopharyngeus" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "pharyngeal muscle abnormalities" EXACT []
is_a: MT:0000759 ! skeletal muscle morphology
is_a: MT:0002234 ! pharynx morphology

[Term]
id: MT:0002254
name: reproductive system inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in any of the reproductive organs" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
is_a: MT:0001846 ! tissue specific inflammatory response
is_a: MT:0001919 ! reproductive system physiology

[Term]
id: MT:0002255
name: glottis morphology
namespace: Trait.ontology
def: "any structural anomaly of the vocal apparatus of the larynx, which includes the vocal cords and the opening between them" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology_2nd edition:ISBN 0-397-51047-0]
synonym: "abnormal glottis" EXACT []
is_a: MT:0002249 ! larynx morphology

[Term]
id: MT:0002256
name: laryngeal cartilage morphology
namespace: Trait.ontology
def: "any structural anomaly of the cartilaginous structures that support the larynx" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology_2nd edition:ISBN 0-397-51047-0]
synonym: "abnormal laryngeal cartilage" EXACT []
is_a: MT:0000163 ! cartilage morphology
is_a: MT:0002249 ! larynx morphology

[Term]
id: MT:0002257
name: arytenoid cartilage morphology
namespace: Trait.ontology
def: "any structural anomaly of the paired triangular cartilages located postlaterally at the level of the thyroid cartilage" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology_2nd edition:ISBN 0-397-51047-0]
comment: the vocal cords are attached to the arytenoid cartilages; their movement facilitates the vibration of the vocal cords
synonym: "abnormal arytenoid cartilage" EXACT []
is_a: MT:0002256 ! laryngeal cartilage morphology

[Term]
id: MT:0002258
name: cricoid cartilage morphology
namespace: Trait.ontology
def: "any structural anomaly of the most inferior of the laryngeal cartilages" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology_2nd edition:ISBN 0-397-51047-0]
synonym: "abnormal cricoid cartilage" EXACT []
is_a: MT:0002256 ! laryngeal cartilage morphology

[Term]
id: MT:0002259
name: epiglottis morphology
namespace: Trait.ontology
def: "any structural anomaly of the most superior of the laryngeal cartilages, which is found at the root of the tongue and folds back over the entrance to the larynx during swallowing" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology_2nd edition:ISBN 0-397-51047-0]
synonym: "abnormal epiglottis" EXACT []
is_a: MT:0002256 ! laryngeal cartilage morphology

[Term]
id: MT:0002260
name: thyroid cartilage morphology
namespace: Trait.ontology
def: "any structural anomaly of the largest of the laryngeal cartilages" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology_2nd edition:ISBN 0-397-51047-0]
comment: the thyroid cartilage consists of two fused plates; their point of fusion is the "Adam's apple"
synonym: "abnormal thyroid cartilage" EXACT []
is_a: MT:0002256 ! laryngeal cartilage morphology

[Term]
id: MT:0002261
name: laryngeal mucosa morphology
namespace: Trait.ontology
def: "any structural anomaly of the mucous lining of the larynx, which is composed of squamous epithelium in the upper larynx and ciliated columnar epithelium in the lower larynx" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology_2nd edition:ISBN 0-397-51047-0]
synonym: "abnormal laryngeal mucosa" EXACT []
is_a: MT:0002249 ! larynx morphology
is_a: MT:0002277 ! respiratory mucosa morphology

[Term]
id: MT:0002262
name: nasal mucosa goblet cell morphology
namespace: Trait.ontology
def: "any structural abnormality of the cells lining the nasal epithelium that produce and secrete mucins" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal goblet cells of the nasal mucosa" EXACT []
synonym: "abnormal nasal mucous membrane" EXACT []
is_a: MT:0002238 ! nasal mucosa morphology

[Term]
id: MT:0002263
name: laryngeal muscle morphology
namespace: Trait.ontology
def: "any structural anomaly of the muscles associated with the larynx" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings, Pathology_2nd edition:ISBN 0-397-51047-0]
synonym: "abnormal laryngeal muscles" EXACT []
is_a: MT:0000759 ! skeletal muscle morphology
is_a: MT:0002249 ! larynx morphology

[Term]
id: MT:0002264
name: bronchus morphology
namespace: Trait.ontology
def: "any structural anomaly of the upper conducting airways of the lung; these airways arise from the terminus of the trachea" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings, Pathology_2nd edition:ISBN 0-397-51047-0]
comment: the bronchi contain both cartilage and mucous glands in their walls
synonym: "abnormal bronchi" EXACT []
is_a: MT:0004391 ! respiratory conducting tube

[Term]
id: MT:0002265
name: left major bronchus morphology
namespace: Trait.ontology
def: "any structural anomaly of the conducting airway leading to the left lobe of the lungs" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology_2nd edition:ISBN 0-397-51047-0]
synonym: "abnormal left major bronchus" EXACT []
is_a: MT:0002264 ! bronchus morphology

[Term]
id: MT:0002266
name: right major bronchus morphology
namespace: Trait.ontology
def: "any structural anomaly of the conducting airway leading to the right lobe of the lungs" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology_2nd edition:ISBN 0-397-51047-0]
synonym: "abnormal right major bronchus" EXACT []
is_a: MT:0002264 ! bronchus morphology

[Term]
id: MT:0002267
name: bronchiole morphology
namespace: Trait.ontology
def: "any structural anomaly of the conducting airway of the lungs found terminal to the bronchi; these structures contain neither cartilage nor mucous-secreting glands; the epithelium of the bronchioles becomes thinner with each branching" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology_2nd edition:ISBN 0-397-51047-0]
synonym: "abnormal bronchioles" EXACT []
is_a: MT:0004391 ! respiratory conducting tube

[Term]
id: MT:0002268
name: terminal bronchiole morphology
namespace: Trait.ontology
def: "any structural anomaly of the last conducting structure of non-respiratory bronchioles; after this point, the airways have alveoli in their walls" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology_2nd edition:ISBN 0-397-51047-0]
synonym: "abnormal terminal bronchioles" EXACT []
is_a: MT:0002267 ! bronchiole morphology

[Term]
id: MT:0002269
name: muscle size
namespace: Trait.ontology
def: "a wasting of muscle tissue resulting in a derangement of the muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [cml:Cathleen M. Lutz_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "muscle atrophy" EXACT []
is_a: MT:0002108 ! muscle morphology

[Term]
id: MT:0002270
name: respiratory alveoli morphology
namespace: Trait.ontology
def: "any structural anomaly of the small sac-like dilations of the distal airspace of the lung; they are present along the walls of the alveolar sacs, alveolar ducts and terminal bronchioles; gas exchange of oxygen and carbon dioxide between alveolar air and blood in the pulmonary capillaries takes place across the cell walls" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal alveoli" EXACT []
synonym: "abnormal pulmonary alveoli morphology" EXACT []
is_a: MT:0001175 ! lung morphology

[Term]
id: MT:0002271
name: respiratory alveolar duct morphology
namespace: Trait.ontology
def: "any structural anomaly of the respiratory conducting tubes distal to the respiratory bronchiole that lead to the alveolar sacs and the alveoli" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal alveolar ducts" EXACT []
is_a: MT:0004391 ! respiratory conducting tube

[Term]
id: MT:0002272
name: nervous system electrophysiology
namespace: Trait.ontology
alt_id: MT:0002677
def: "anomaly in the function of the nervous system as it relates to electrical phenomena" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal electrophysiology" EXACT []
synonym: "electrophysiology abnormalities" EXACT []
synonym: "PNS electrophysiology abnormalities" NARROW []
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0002273
name: respiratory alveolar epithelial cell morphology
namespace: Trait.ontology
def: "any structural anomaly of the cells lining the alveoli" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal alveolar epithelial cells" EXACT []
synonym: "abnormal lung epithelial cells" EXACT []
is_a: MT:0002270 ! respiratory alveoli morphology

[Term]
id: MT:0002274
name: type I pneumocyte morphology
namespace: Trait.ontology
def: "any structural anomaly of the epithelial cells lining the alveoli through which gas exchange occurs; these are thin cells with a large surface area" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology_2nd edition:ISBN 0-397-51047-0]
synonym: "abnormal type I cells" EXACT []
synonym: "abnormal type I pneumocytes" EXACT []
is_a: MT:0002273 ! respiratory alveolar epithelial cell morphology

[Term]
id: MT:0002275
name: type II pneumocyte morphology
namespace: Trait.ontology
def: "any structural anomaly of the epithelial cells lining the alveoli that produce surfactant" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology_2nd edition:ISBN 0-397-51047-0]
synonym: "abnormal type II cells" EXACT []
synonym: "abnormal type II pneumocytes" EXACT []
is_a: MT:0002273 ! respiratory alveolar epithelial cell morphology

[Term]
id: MT:0002276
name: lung interstitium morphology
namespace: Trait.ontology
def: "any structural anomaly of the lung tissue, but not including the conducting airways (bronchi, bronchioles, alveoli)" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology_2nd edition:ISBN 0-397-51047-0]
synonym: "abnormal lung interstitium" EXACT []
synonym: "abnormal pulmonary interstitium" EXACT []
is_a: MT:0001175 ! lung morphology

[Term]
id: MT:0002277
name: respiratory mucosa morphology
namespace: Trait.ontology
def: "structural anomaly of the mucous membrane lining the respiratory tract" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_pig
synonym: "abnormal respiratory mucosa" EXACT []
is_a: MT:0002132 ! respiratory system morphology

[Term]
id: MT:0002278
name: respiratory muscle morphology
namespace: Trait.ontology
def: "structural anomaly of any of the muscles involved in breathing" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_pig
is_a: MT:0002132 ! respiratory system morphology

[Term]
id: MT:0002279
name: diaphragm morphology
namespace: Trait.ontology
alt_id: MT:0000760
def: "structural defect in the thin musculomebranous barrier that separates the abdominal and thoracic cavities; these muscles often used for breathing control" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_pig
synonym: "abnormal diaphragm muscle" EXACT []
is_a: MT:0002278 ! respiratory muscle morphology
is_a: MT:0003358 ! hypaxial muscle morphology

[Term]
id: MT:0002280
name: intercostal muscle morphology
namespace: Trait.ontology
def: "anomaly in the respiratory muscles that arise from the lower border of one rib and insert into the upper border of the adjoining rib" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_cattle
synonym: "abnormal intercostal muscles" EXACT []
is_a: MT:0002278 ! respiratory muscle morphology
is_a: MT:0003358 ! hypaxial muscle morphology

[Term]
id: MT:0002281
name: respiratory mucosa goblet cell morphology
namespace: Trait.ontology
def: "structural anomaly of the cells of the respiratory epithelial lining that produce and secrete mucins" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002277 ! respiratory mucosa morphology

[Term]
id: MT:0002282
name: trachea morphology
namespace: Trait.ontology
def: "structural anomaly of the tube descending from the larynx and branching into the right and left main bronchi" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002132 ! respiratory system morphology

[Term]
id: MT:0002284
name: tracheal smooth muscle morphology
namespace: Trait.ontology
def: "structural anomaly of the smooth muscle lining the trachea" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology:ISBN 0-397-51047-0]
is_a: MT:0000767 ! smooth muscle morphology
is_a: MT:0002282 ! trachea morphology

[Term]
id: MT:0002285
name: tracheal ciliated epithelium morphology
namespace: Trait.ontology
def: "structural anomaly of the epithelial lining of the trachea which contains numerous ciliated cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology:ISBN 0-397-51047-0]
is_a: MT:0002282 ! trachea morphology

[Term]
id: MT:0002286
name: cryptorchism
namespace: Trait.ontology
def: "failure of one or both of the testes to descend into the scrotum around the time of birth" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "cryptorchidism" EXACT []
synonym: "undescended testes" EXACT []
is_a: MT:0001146 ! testis morphology

[Term]
id: MT:0002292
name: gestational length
namespace: Trait.ontology
def: "anomaly in the usual duration of time between when a fertilized egg implants in the wall of the uterus and the birth of offspring" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_pig
is_a: MT:0003699 ! female reproductive system physiology

[Term]
id: MT:0002295
name: pulmonary circulation
namespace: Trait.ontology
alt_id: MT:0001941
def: "flow of blood through the lungs" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "respiratory circulation" EXACT []
is_a: MT:0002128 ! blood circulation
is_a: MT:0002133 ! respiratory system physiology

[Term]
id: MT:0002296
name: aspiration
namespace: Trait.ontology
def: "inspiration into the airways of fluid or any foreign material " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002314 ! respiratory mechanics

[Term]
id: MT:0002297
name: forced expiratory flow rates
namespace: Trait.ontology
def: "anomaly in the rates of airflow during forced vital capacity determination" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002327 ! respiratory function

[Term]
id: MT:0002304
name: total lung capacity
namespace: Trait.ontology
def: "anomaly in the volume of air contained in the lungs at the end of maximal inspiration" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0001942 ! lung volume
is_a: MT:0002314 ! respiratory mechanics

[Term]
id: MT:0002306
name: functional residual capacity
namespace: Trait.ontology
def: "anomaly in the volume of air remaining in the lungs at the end of a normal expiration" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002304 ! total lung capacity

[Term]
id: MT:0002308
name: residual volume
namespace: Trait.ontology
def: "anomaly in the volume of air remaining in the lungs at the end of maximal expiration" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002306 ! functional residual capacity

[Term]
id: MT:0002309
name: vital capacity
namespace: Trait.ontology
def: "anomaly in the amount of air that is exhaled by a maximal expiration following a maximal inspiration" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002304 ! total lung capacity

[Term]
id: MT:0002310
name: susceptibility to fatty liver development
namespace: Trait.ontology
def: "less likely than normal to develop hepatic steatosis " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002628 ! fatty liver

[Term]
id: MT:0002311
name: inspiratory capacity
namespace: Trait.ontology
def: "anomaly in the maximal volume of air that can be inspired after the end of a normal expiration" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002309 ! vital capacity

[Term]
id: MT:0002312
name: inspiratory reserve volume
namespace: Trait.ontology
def: "anomaly in the extra volume of air that can be inspired with maximal effort after reaching the end of a normal inspiration" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002311 ! inspiratory capacity

[Term]
id: MT:0002313
name: tidal volume
namespace: Trait.ontology
def: "anomaly in the volume of air inspired or expired during each normal respiratory cycle" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002311 ! inspiratory capacity

[Term]
id: MT:0002314
name: respiratory mechanics
namespace: Trait.ontology
def: "anomaly in the action of the lungs, diaphragm, ribs and chest wall during respiration" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0001943 ! respiration

[Term]
id: MT:0002315
name: respiratory signs/symptoms
namespace: Trait.ontology
def: "manifestations of diseases of the respiratory tract " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0001943 ! respiration

[Term]
id: MT:0002317
name: dyspnea
namespace: Trait.ontology
def: "shortness of breath; distress in breathing " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "gasping" EXACT []
is_a: MT:0001951 ! breathing

[Term]
id: MT:0002320
name: alveolar ventilation
namespace: Trait.ontology
def: "increased alveolar ventilation relative to metabolic carbon dioxide production; results in carbon dioxide pressure decreasing below normal" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002315 ! respiratory signs/symptoms
is_a: MT:0002338 ! pulmonary ventilation

[Term]
id: MT:0002322
name: respiratory transport
namespace: Trait.ontology
def: "anomaly in the process of gas exchange" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0001943 ! respiration

[Term]
id: MT:0002323
name: susceptibility to induced hyperlipidemia
namespace: Trait.ontology
def: "less likely than normal to develop abnormally high levels of circulating lipids" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002118 ! lipid homeostasis

[Term]
id: MT:0002324
name: blood-air barrier
namespace: Trait.ontology
def: "anomaly in the membrane between the capillary blood and alveolar air, comprised of the alveolar epithelium and the capillary epithelium and their adherent basement membranes and epithelial cell cytoplasm " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0001175 ! lung morphology
is_a: MT:0002336 ! pulmonary gas exchange

[Term]
id: MT:0002325
name: pulmonary diffusing capacity
namespace: Trait.ontology
def: "anomaly in the amount of gas taken up by pulmonary capillary blood per minute per unit of average oxygen pressure gradient between alveolar gas and pulmonary capillary blood" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002336 ! pulmonary gas exchange

[Term]
id: MT:0002326
name: ventilation-perfusion ratio
namespace: Trait.ontology
def: "ratio of alveolar ventilation to simultaneous capillary blood flow in the lung" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
comment: changes in this ratio alter the amount of O2 or CO2 in the blood
is_a: MT:0002295 ! pulmonary circulation
is_a: MT:0002336 ! pulmonary gas exchange
is_a: MT:0002338 ! pulmonary ventilation

[Term]
id: MT:0002327
name: respiratory function
namespace: Trait.ontology
def: "anomaly in any measure of the processes involved in respiration" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0001943 ! respiration

[Term]
id: MT:0002328
name: airway resistance
namespace: Trait.ontology
def: "anomaly in the opposition to flow of air caused by the forces of friction, measured as the ratio of driving pressure to the rate of air flow" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002314 ! respiratory mechanics
is_a: MT:0002327 ! respiratory function

[Term]
id: MT:0002329
name: blood gas level
namespace: Trait.ontology
def: "anomaly in the amount of oxygen and carbon dioxide in the blood" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0003948 ! gas homeostasis

[Term]
id: MT:0002330
name: bronchial provocation
namespace: Trait.ontology
def: "anomaly in the results of measures of responsiveness to allergens, pharmacological solutions, or control solutions" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
comment: used in asthma diagnosis
is_a: MT:0002327 ! respiratory function

[Term]
id: MT:0002332
name: exercise endurance
namespace: Trait.ontology
def: "improved or impaired performance during controlled physical activity" [MeSH:National Library of Medicine_Medical Subject Headings, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal exercise fitness" EXACT []
synonym: "abnormal exercise tests" EXACT []
is_a: MT:0002121 ! metabolism

[Term]
id: MT:0002333
name: lung compliance
namespace: Trait.ontology
def: "anomalous pulmonary volume change per unit pressure change " [MeSH:National Library of Medicine_Medical Subject Headings]
comment: this is a measure of the stiffness of the lung and indicative for diseases that cause fibrosis or edema in the lungs
is_a: MT:0002314 ! respiratory mechanics
is_a: MT:0002327 ! respiratory function

[Term]
id: MT:0002334
name: airway responsiveness
namespace: Trait.ontology
alt_id: MT:0002331
def: "anomalous response in bronchial provocation tests" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal methacholine challenge" EXACT []
is_a: MT:0002330 ! bronchial provocation

[Term]
id: MT:0002336
name: pulmonary gas exchange
namespace: Trait.ontology
def: "anomaly in the exchange of oxygen and carbon dioxide between the alveolar air and pulmonary capillary blood" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002322 ! respiratory transport

[Term]
id: MT:0002337
name: whole-body plethysmography
namespace: Trait.ontology
def: "anomaly in the measurements gathered in a chamber that encloses the body and in which changes in volume are recorded" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002327 ! respiratory function

[Term]
id: MT:0002338
name: pulmonary ventilation
namespace: Trait.ontology
def: "anomaly in the total volume of gas per minute inspired or expired " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002314 ! respiratory mechanics

[Term]
id: MT:0002339
name: lymph node morphology
namespace: Trait.ontology
alt_id: MT:0000699
def: "anomalous structure, size, or cellularity of the oval or bean shaped bodies located along the lymphatic system" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal lymph node" EXACT []
synonym: "lymph node abnormalities" EXACT []
is_a: MT:0002722 ! immune system organ morphology

[Term]
id: MT:0002340
name: axillary lymph node morphology
namespace: Trait.ontology
def: "anomalous structure, development, or number of the lymph nodes located in the upper body" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "axillary lymph node abnormalities" EXACT []
is_a: MT:0002339 ! lymph node morphology

[Term]
id: MT:0002342
name: lymph node trabeculae
namespace: Trait.ontology
def: "anomaly of the supporting structure of the lymph node" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
is_a: MT:0005024 ! lymph node structure

[Term]
id: MT:0002343
name: lymph node cortex morphology
namespace: Trait.ontology
def: "anomaly in the outer area of the lymph node that has B and T cell domains" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
is_a: MT:0005024 ! lymph node structure

[Term]
id: MT:0002344
name: lymph node B cell domain morphology
namespace: Trait.ontology
def: "anomaly in the lymph node cortex in which B lymphocytes reside" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology:ISBN 0-397-51047-0]
synonym: "abnormal B cell dependent cortex" EXACT []
synonym: "abnormal B-cell domain" EXACT []
synonym: "abnormal lymph node germinal center" EXACT []
is_a: MT:0002343 ! lymph node cortex morphology

[Term]
id: MT:0002345
name: lymph node primary follicle morphology
namespace: Trait.ontology
def: "anomaly in the immunologically inactive B cell area of the lymph node cortex" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology:ISBN 0-397-51047-0]
comment: cells in the primary follicle consist of cohesive aggregates of small, normal-appearing lymphocytes
is_a: MT:0002344 ! lymph node B cell domain morphology

[Term]
id: MT:0002346
name: lymph node secondary follicle morphology
namespace: Trait.ontology
def: "anomaly in the immunologically active area of the lymph node cortex " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology:ISBN 0-397-51047-0]
comment: cells size in the germinal centers varies
synonym: "abnormal germinal centers" EXACT []
is_a: MT:0002344 ! lymph node B cell domain morphology

[Term]
id: MT:0002347
name: lymph node T cell domain morphology
namespace: Trait.ontology
def: "anomaly in the area of the lymph node in which T lymphocytes reside" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7, Pathology:ISBN 0-397-51047-0]
synonym: "abnormal T cell dependent paracortex" EXACT []
synonym: "abnormal T-cell domain" EXACT []
synonym: "deep cortex" EXACT []
is_a: MT:0002343 ! lymph node cortex morphology

[Term]
id: MT:0002348
name: lymph node medulla morphology
namespace: Trait.ontology
def: "anomaly in the area of the lymph node through which lymph leaves the node; it contains macrophages and antibody-secreting plasma cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "abnormal medullary sinus" EXACT []
is_a: MT:0005024 ! lymph node structure

[Term]
id: MT:0002349
name: afferent lymphatic vessel morphology
namespace: Trait.ontology
def: "structural anomaly in the tube entering the lymph node" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0001879 ! lymphatic vessel morphology
is_a: MT:0005024 ! lymph node structure

[Term]
id: MT:0002350
name: efferent lymphatic vessel morphology
namespace: Trait.ontology
def: "structural anomaly in the tube exiting the lymph node" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0001879 ! lymphatic vessel morphology
is_a: MT:0005024 ! lymph node structure

[Term]
id: MT:0002351
name: cervical lymph node morphology
namespace: Trait.ontology
def: "anomalous structure, development, or number of the lymph nodes found near the neck and shoulders" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "cervical lymph node abnormalities" EXACT []
is_a: MT:0002339 ! lymph node morphology

[Term]
id: MT:0002352
name: popliteal lymph node morphology
namespace: Trait.ontology
def: "anomalous structure, development, or number of the lymph nodes which drain the legs" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "popliteal lymph node abnormalities" EXACT []
is_a: MT:0002339 ! lymph node morphology

[Term]
id: MT:0002353
name: inguinal lymph node morphology
namespace: Trait.ontology
def: "anomalous structure, development, or number of the lymph nodes located in the groin area" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "inguinal lymph node abnormalities" EXACT []
is_a: MT:0002339 ! lymph node morphology

[Term]
id: MT:0002354
name: spleen trabecular artery integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of one of the branches of the splenic artery" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0000689 ! spleen morphology
is_a: MT:0003410 ! artery integrity

[Term]
id: MT:0002356
name: spleen red pulp morphology
namespace: Trait.ontology
def: "anomalous structure of the area of the spleen that screens and eliminates defective or foreign cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology:ISBN 0-397-51047-0]
is_a: MT:0000689 ! spleen morphology

[Term]
id: MT:0002357
name: spleen white pulp morphology
namespace: Trait.ontology
def: "anomalous structure or formation of the splenic area consisting of lymph nodules and diffuse lymphatic tissue" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
is_a: MT:0000689 ! spleen morphology

[Term]
id: MT:0002358
name: spleen periarteriolar lymphoid sheath morphology
namespace: Trait.ontology
def: "anomalous structure of the area of the spleen in which T cells surround the central arteriole" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7, Pathology:ISBN 0-397-51047-0]
synonym: "abnormal PALS" EXACT []
synonym: "abnormal T cell domain of the splenic white pulp" EXACT []
is_a: MT:0002357 ! spleen white pulp morphology

[Term]
id: MT:0002359
name: spleen germinal center morphology
namespace: Trait.ontology
def: "anomalous structure or formation of the area of the spleen in which activated follicles are located" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology:ISBN 0-397-51047-0]
is_a: MT:0002357 ! spleen white pulp morphology

[Term]
id: MT:0002360
name: spleen B cell corona morphology
namespace: Trait.ontology
def: "anomalous structure of the area of the splenic white pulp dominated by B lymphocyte follicles" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology:ISBN 0-397-51047-0]
synonym: "abnormal B cell domain of the spleen" EXACT []
synonym: "abnormal spleen B-cell corona" EXACT []
is_a: MT:0002357 ! spleen white pulp morphology

[Term]
id: MT:0002361
name: spleen central arteriole morphology
namespace: Trait.ontology
def: "anomalous structure of the blood vessel within the spleen that connects the trabecular artery to the trabecular vein" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
is_a: MT:0002357 ! spleen white pulp morphology

[Term]
id: MT:0002362
name: spleen marginal zone morphology
namespace: Trait.ontology
def: "anomalous structure of the area surrounding the marginal sinus and containing lymphocytes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
is_a: MT:0000689 ! spleen morphology

[Term]
id: MT:0002363
name: spleen marginal sinus morphology
namespace: Trait.ontology
def: "anomalous structure of the area of the spleen through which blood enters" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
is_a: MT:0000689 ! spleen morphology

[Term]
id: MT:0002364
name: thymus size
namespace: Trait.ontology
def: "deviation from the normal size of the thymus" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0000703 ! thymus morphology
is_a: MT:0002221 ! lymph organ size

[Term]
id: MT:0002365
name: thymus cellularity
namespace: Trait.ontology
def: "anomaly in the cellular makeup of the thymus" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0000703 ! thymus morphology
is_a: MT:0002222 ! lymph organ cellularity

[Term]
id: MT:0002367
name: thymus lobule morphology
namespace: Trait.ontology
def: "anomalous structure or development of the basic structural unit of the thymus" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology:ISBN 0-397-51047-0]
synonym: "abnormal thymus lobule" EXACT []
is_a: MT:0000703 ! thymus morphology

[Term]
id: MT:0002368
name: thymus capsule morphology
namespace: Trait.ontology
def: "anomalous structure or development of the fibrous connective tissue surrounding the thymus" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal thymus capsule" EXACT []
is_a: MT:0000703 ! thymus morphology

[Term]
id: MT:0002369
name: thymus subcapsular epithelium morphology
namespace: Trait.ontology
def: "anomalous structure or development of the epithelial cells lining the capsule and trabeculae of the thymus" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "abnormal subcapsular epithelium of the thymus" EXACT []
is_a: MT:0002368 ! thymus capsule morphology

[Term]
id: MT:0002370
name: thymus trabeculae morphology
namespace: Trait.ontology
def: "anomalous structure or development of the thymic connective tissue which extends into the parenchyma" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology:ISBN 0-397-51047-0]
is_a: MT:0000703 ! thymus morphology

[Term]
id: MT:0002371
name: thymus cortex morphology
namespace: Trait.ontology
def: "anomalous structure or development of the outer area of thymus lobules" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
comment: the cortex contains immature thymocytes, cortical epithelial cells, and scattered macrophages
synonym: "abnormal thymus cortex" EXACT []
is_a: MT:0002367 ! thymus lobule morphology

[Term]
id: MT:0002375
name: thymus medulla morphology
namespace: Trait.ontology
def: "anomalous structure or development of the inner area of thymus lobules" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
comment: the medulla contains mature thymocytes, medualla epithelial cells, macrophages and dendritic cells
synonym: "abnormal thymus medulla" EXACT []
is_a: MT:0002367 ! thymus lobule morphology

[Term]
id: MT:0002376
name: dendritic cell physiology
namespace: Trait.ontology
def: "failure or atypical function of the immunocompetent cells of the lymphoid and hemopoietic systems and skin, which function to process antigens and present them to T cells, thus stimulating cellular immunity" [J:85808, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal dendritic cell function" EXACT []
synonym: "abnormal interdigitating reticular cell" EXACT []
is_a: MT:0001819 ! immune cell physiology

[Term]
id: MT:0002377
name: mucosa-associated lymphoid tissue morphology
namespace: Trait.ontology
def: "anomalous structure or development of the regional immune system associated with the mucosa" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "MALT abnormalities" EXACT []
synonym: "mucosa-associated lymphoid tissue abnormalities" EXACT []
is_a: MT:0002722 ! immune system organ morphology

[Term]
id: MT:0002378
name: gut-associated lymphoid tissue morphology
namespace: Trait.ontology
def: "anomalous structure or development of the regional immune system located in the gut" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "GALT abnormalities" EXACT []
synonym: "gut-associated lymphoid tissue abnormalities" EXACT []
is_a: MT:0002722 ! immune system organ morphology

[Term]
id: MT:0002379
name: oropharyngeal lymphoid tissue morphology
namespace: Trait.ontology
def: "anomalous structure or development of the circular lymphoid tissue formed by the lingual, pharyngeal, and faucial tonsils" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal oropharyngeal lymphoid tissue" EXACT []
synonym: "abnormal Waldeyer's ring" EXACT []
is_a: MT:0002377 ! mucosa-associated lymphoid tissue morphology

[Term]
id: MT:0002380
name: tonsil morphology
namespace: Trait.ontology
def: "anomalous structure or development of either of the two small almond-shaped masses of lymph tissue found on either side of the oropharynx" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal palatine tonsils" EXACT []
is_a: MT:0002379 ! oropharyngeal lymphoid tissue morphology

[Term]
id: MT:0002384
name: nasopharyngeal tonsil morphology
namespace: Trait.ontology
def: "anomalous structure or development of the lymph tissue in the roof and posterior wall of the nasopharynx" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal adenoids" EXACT []
is_a: MT:0002379 ! oropharyngeal lymphoid tissue morphology

[Term]
id: MT:0002385
name: lingual tonsillar tissue morphology
namespace: Trait.ontology
def: "anomalous structure or development of the lymph tissue on the floor of the oropharyngeal passage, near the root of the tongue" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal lingual tonsillar tissue" EXACT []
is_a: MT:0002379 ! oropharyngeal lymphoid tissue morphology

[Term]
id: MT:0002386
name: tubal tonsil morphology
namespace: Trait.ontology
def: "anomalous structure or development of the lymph tissue associated with the pharyngeal opening of the auditory tube" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002379 ! oropharyngeal lymphoid tissue morphology

[Term]
id: MT:0002387
name: prevalence of Peyer's patches
namespace: Trait.ontology
def: "the distribution and/or number of Peyer's patches " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0000696 ! Peyer's patch morphology

[Term]
id: MT:0002388
name: Peyer's patch epithelium morphology
namespace: Trait.ontology
def: "anomalous structure of the specialized epithelium of the Peyer's patch " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
comment: antigen normally enters the Peyer's patch via this specialized epithelium
synonym: "abnormal M cells" EXACT []
is_a: MT:0000696 ! Peyer's patch morphology

[Term]
id: MT:0002389
name: Peyer's patch follicle morphology
namespace: Trait.ontology
def: "anomaly of the structure, development, or size of the Peyer's patch normally occupied by B cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
is_a: MT:0000696 ! Peyer's patch morphology

[Term]
id: MT:0002391
name: Peyer's patch germinal center morphology
namespace: Trait.ontology
def: "anomalous structure or differentiation of the area of the Peyer's patch where B cells proliferate and differentiate into plasma cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
is_a: MT:0000696 ! Peyer's patch morphology

[Term]
id: MT:0002392
name: Peyer's patch T cell area
namespace: Trait.ontology
def: "anomalous structure or development of the Peyer's patch normally occupied by T lymphocytes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "abnormal Peyer's patch T-cell area" EXACT []
is_a: MT:0000696 ! Peyer's patch morphology

[Term]
id: MT:0002393
name: bronchus-associated lymphoid tissue morphology
namespace: Trait.ontology
def: "anomalous structure or development of the regional immune system located near the bronchus" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "BALT abnormalities" EXACT []
synonym: "bronchial-associated lymphoid tissue abnormalities" EXACT []
synonym: "bronchus-associated lymphoid tissue abnormalities" EXACT []
is_a: MT:0002722 ! immune system organ morphology

[Term]
id: MT:0002396
name: hematopoietic system morphology/development
namespace: Trait.ontology
def: "any structural or developmental anomaly of the blood cells or the organs associated with the development and formation of blood cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "abnormal blood morphology" EXACT []
synonym: "abnormal hemopoietic system morphology/development" EXACT []
synonym: "hematopoietic organ abnormalities" EXACT []
is_a: MT:0005397 ! hematopoietic system trait

[Term]
id: MT:0002397
name: bone marrow morphology
namespace: Trait.ontology
def: "structural anomalies in the soft tissue that fills the cavities of bones" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "bone marrow abnormalities" EXACT []
is_a: MT:0003795 ! bone structure

[Term]
id: MT:0002398
name: bone marrow cell morphology/development
namespace: Trait.ontology
def: "anomalous structure or formation of the cells found in the bone marrow" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_pig
synonym: "bone marrow cell abnormalities" EXACT []
is_a: MT:0002396 ! hematopoietic system morphology/development

[Term]
id: MT:0002399
name: pluripotent precursor cell morphology/development
namespace: Trait.ontology
def: "anomalous structure or formation of the cells that give rise to most types of cells necessary for fetal development" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "pluripotent stem cell abnormalities" EXACT []
is_a: MT:0002085 ! embryonic tissue morphology

[Term]
id: MT:0002400
name: multipotent stem cell morphology/development
namespace: Trait.ontology
def: "anomalies of the specialized cells that are committed to giving rise to cells with particular functions" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002399 ! pluripotent precursor cell morphology/development

[Term]
id: MT:0002401
name: lymphopoiesis
namespace: Trait.ontology
alt_id: MT:0000310
alt_id: MT:0001640
alt_id: MT:0001880
def: "atypical formation of lymphocytes and plasma cells from lymphoid stem cells which develop from the pluripotent hematopoietic stem cells in the bone marrow; these lymphoid stem cells differentiate into T-lymphocytes; B-lymphocytes; plasma cells; or NK-cells (natural killer cells), depending on the organ or tissues to which they migrate" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_pig
synonym: "abnormal lymphopoiesis" EXACT []
synonym: "lymphoid stem cell abnormalities" EXACT []
synonym: "lymphopoiesis abnormalities" EXACT []
is_a: MT:0005460 ! leukopoiesis

[Term]
id: MT:0002403
name: pre-B cell morphology/development
namespace: Trait.ontology
def: "anomalous structure, development, or number of the cells in the B lymphocyte lineage that have undergone VDJ rearrangement of the immunoglobulin heavy chain and are in the process of V-J rearrangement of the light chain: these cells express mu heavy chain on the cell surface" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
comment: these cells express the mu heavy chain in both the cytoplasm and on the cell surface; in addition to the mu heavy chain, other cell surface markers include: CD45R, MHC class II, CD19, CD20, CD38, CD40
synonym: "pre-B cell abnormalities" EXACT []
synonym: "pre-B-cell abnormalities" EXACT []
is_a: MT:0002144 ! B lymphocyte development

[Term]
id: MT:0002404
name: intestinal adenoma
namespace: Trait.ontology
def: "benign tumors of the small and large intestine" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "intestinal adenomata" EXACT []
is_a: MT:0002815 ! adenoma

[Term]
id: MT:0002405
name: respiratory system inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the respiratory system" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
subset: slim_pig
is_a: MT:0001846 ! tissue specific inflammatory response
is_a: MT:0002133 ! respiratory system physiology

[Term]
id: MT:0002407
name: double-negative T cell morphology/development
namespace: Trait.ontology
def: "anomalous structure, development, or number of the subset of T cells found in the thymus that express neither CD4 nor CD8" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
comment: these are precursors to mature T cells; normally, they do not circulate, but are found in the thymus; they have not undergone rearrangement of the alpha and beta T cell receptor genes
synonym: "CD4-CD8- T cell abnormalities" EXACT []
synonym: "double-negative T cell abnormalities" EXACT []
synonym: "double-negative T-cell abnormalities" EXACT []
is_a: MT:0002145 ! T lymphocyte development

[Term]
id: MT:0002408
name: double-positive T cell morphology/development
namespace: Trait.ontology
def: "anomalous development or number of the subset of T cells found in the thymus that express both CD4 and CD8" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
comment: these cells are precursors to mature T cells and are generally located in the thymus; during their development, the alpha and beta chains of the T cell receptor are rearranged and the receptor can be expressed
synonym: "CD4+CD8+ T cell abnormalities" EXACT []
synonym: "double-positive T cell abnormalities" EXACT []
synonym: "double-positive T-cell abnormalities" EXACT []
is_a: MT:0002145 ! T lymphocyte development

[Term]
id: MT:0002410
name: susceptibility to viral infection
namespace: Trait.ontology
def: "reduced likelihood that an organism will develop ill effects from a viral infection or from components of or toxins produced by a virus" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_pig
synonym: "increased resistance to viral infection" EXACT []
is_a: MT:0001793 ! susceptibility to infection

[Term]
id: MT:0002411
name: susceptibility to bacterial infection
namespace: Trait.ontology
def: "reduced likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_pig
synonym: "increased resistance to bacterial infection" EXACT []
is_a: MT:0001793 ! susceptibility to infection

[Term]
id: MT:0002413
name: megakaryoblast morphology/development
namespace: Trait.ontology
def: "anomalous structure or development of the progenitor cells of the thrombocytic (platelet) line of cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "megakaryoblast abnormalities" EXACT []
is_a: MT:0002398 ! bone marrow cell morphology/development

[Term]
id: MT:0002414
name: myeloblast morphology/development
namespace: Trait.ontology
def: "anomalous structure, formation, or numbers of the cells found in the bone marrow that give rise to the granulocyte line of blood cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_pig
synonym: "myeloblast abnormalities" EXACT []
is_a: MT:0002398 ! bone marrow cell morphology/development

[Term]
id: MT:0002415
name: neutrophil morphology/development
namespace: Trait.ontology
def: "anomalous structure, differentiation, or number of the granular leukocytes that have a three- to five-lobed nucleus and a cytoplasm that contains inconspicuous granules stainable by neutral dyes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_pig
synonym: "neutrophil abnormalities" EXACT []
is_a: MT:0002414 ! myeloblast morphology/development
is_a: MT:0002441 ! granulocyte morphology/development

[Term]
id: MT:0002416
name: proerythroblast morphology/development
namespace: Trait.ontology
def: "anomalous structure, formation, or numbers of the immature, nucleated erythrocyte precursors that give rise to reticulocytes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal erythroid progenitor morphology/development" EXACT []
synonym: "normoblast abnormalities" EXACT []
synonym: "proerythroblast abnormalities" EXACT []
is_a: MT:0002398 ! bone marrow cell morphology/development

[Term]
id: MT:0002417
name: megakaryocyte morphology/development
namespace: Trait.ontology
def: "anomalous structure or formation of the very large cells found in the bone marrow that release platelets" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "megakaryocyte abnormalities" EXACT []
is_a: MT:0002413 ! megakaryoblast morphology/development

[Term]
id: MT:0002419
name: innate immunity
namespace: Trait.ontology
def: "anomaly in the function of the early phase of the response to infection; normally, it is present at all times, does not increase with exposure to specific pathogens, and does not discriminate between pathogens" [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "innate immunity dysfunction" EXACT []
synonym: "natural immunity abnormalities" EXACT []
is_a: MT:0001790 ! immune system physiology

[Term]
id: MT:0002420
name: adaptive immunity
namespace: Trait.ontology
def: "anomaly in the function of the response of antigen-specific lymphocytes to antigen, including the development of immunological memory" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
subset: slim_pig
synonym: "acquired immune response dysfunction" EXACT []
synonym: "adaptive immunity dysfunction" EXACT []
is_a: MT:0001790 ! immune system physiology

[Term]
id: MT:0002421
name: cell-mediated immunity
namespace: Trait.ontology
def: "abnormal function of any adaptive immune response in which T cells play a main role" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
comment: this encompasses all adaptive immunity that cannot be transferred to a naive recipient with serum antibody (the definition of humoral immunity)
subset: slim_pig
synonym: "cell-mediated immunity dysfunction" EXACT []
is_a: MT:0002420 ! adaptive immunity

[Term]
id: MT:0002422
name: basophil morphology/development
namespace: Trait.ontology
def: "anomalous structure, differentiation, or number of the granular leukocytes that are characterized by pale-staining, lobate nucleus and cytoplasm and contain dark-staining granules of varying size and are stained by basic dyes " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "basophil abnormalities" EXACT []
is_a: MT:0002414 ! myeloblast morphology/development
is_a: MT:0002441 ! granulocyte morphology/development

[Term]
id: MT:0002423
name: mast cell physiology
namespace: Trait.ontology
def: "anomalous response of the granulated cells found in most tissues and which contain large amounts of histamine and heparin in granules" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal mast cell function" EXACT []
synonym: "mast cell abnormalities" EXACT []
is_a: MT:0001819 ! immune cell physiology

[Term]
id: MT:0002424
name: reticulocyte morphology/development
namespace: Trait.ontology
def: "anomalous structure, formation, or numbers of immature erythrocytes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "reticulocyte abnormalities" EXACT []
is_a: MT:0002416 ! proerythroblast morphology/development

[Term]
id: MT:0002425
name: susceptibility to autoimmune disorder
namespace: Trait.ontology
def: "likelihood that an organism will develop disease characterized by production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "autoimmune disorder susceptibility" EXACT []
synonym: "autoimmune disorders" EXACT []
is_a: MT:0001844 ! autoimmune response

[Term]
id: MT:0002427
name: dwarfism
namespace: Trait.ontology
def: "abnormally undersized with disproportionate body parts" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003956 ! body size

[Term]
id: MT:0002428
name: semicircular canal
namespace: Trait.ontology
def: "anomaly of the organ of balance composed of three long bony tubes of the labyrinth" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002729 ! canal morphology

[Term]
id: MT:0002429
name: blood cell morphology/development
namespace: Trait.ontology
alt_id: MT:0000178
alt_id: MT:0000205
alt_id: MT:0001576
alt_id: MT:0002545
def: "anomalous structure, differentiation, or number of any of the cells found in the blood" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "blood cell abnormalities" EXACT []
synonym: "blood cell defects" EXACT []
is_a: MT:0002396 ! hematopoietic system morphology/development

[Term]
id: MT:0002432
name: CD4+ T cell morphology/development
namespace: Trait.ontology
def: "anomalous structure, differentiation, or number of the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "CD4+ T-cell abnormalities" EXACT []
synonym: "helper T cell abnormalities" EXACT []
is_a: MT:0002435 ! effector T cell morphology/development

[Term]
id: MT:0002433
name: T helper 1 morphology/development
namespace: Trait.ontology
def: "anomalous structure, formation, or numbers of the subset of helper T cells that enhance cell-mediated immune responses; these cells secrete IL-1 and gamma-IFN and are generally involved in inflammatory responses" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "T helper 1 abnormalities" EXACT []
synonym: "TH1 abnormalities" EXACT []
synonym: "Th1 abnormalities" EXACT []
is_a: MT:0002432 ! CD4+ T cell morphology/development

[Term]
id: MT:0002434
name: T helper 2 morphology/development
namespace: Trait.ontology
def: "anomalous structure, formation, or numbers of the subset of T helper cells that enhance humoral immunity and inhibit cell-mediated immune responses; these cells produce IL-4 and induce B cells to produce IgE and IgG1, while also supporting eosinophil and mast cell functions" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "T helper 2 abnormalities" EXACT []
synonym: "TH2 abnormalities" EXACT []
synonym: "Th2 abnormalities" EXACT []
is_a: MT:0002432 ! CD4+ T cell morphology/development

[Term]
id: MT:0002435
name: effector T cell morphology/development
namespace: Trait.ontology
def: "anomalous structure, formation, or numbers of the set of T lymphocytes that are able to respond immediately upon contact with cells bearing the appropriate peptide:MHC complex for the cell" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal single positive T cell" EXACT []
synonym: "effector T cell abnormalities" EXACT []
synonym: "effector T-cell abnormalities" EXACT []
is_a: MT:0002145 ! T lymphocyte development

[Term]
id: MT:0002436
name: cytotoxic T cell morphology/development
namespace: Trait.ontology
def: "anomalous structure, formation, or numbers of the subset of CD8+ T lymphocytes capable of directly killing appropriately targeted cells " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "CD8+ T cell abnormalities" EXACT []
synonym: "cytotoxic T cell abnormalities" EXACT []
synonym: "cytotoxic T-cell abnormalities" EXACT []
is_a: MT:0005010 ! CD8+ T cell morphology/development

[Term]
id: MT:0002437
name: suppressor T cell morphology/development
namespace: Trait.ontology
def: "anomalous structure, formation, or numbers of the subset of CD8+ lymphocytes that suppress antibody production or inhibit immune responses" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "suppressor T cell abnormalities" EXACT []
synonym: "suppressor T-cell abnormalities" EXACT []
is_a: MT:0005010 ! CD8+ T cell morphology/development

[Term]
id: MT:0002439
name: plasma cell morphology/development
namespace: Trait.ontology
def: "anomalous structure, differentiation, or number of the specialized forms of B-lymphocytes which produce and secrete immunoglobulin" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
comment: these are terminally differentiated B cells and no longer respond to antigens or helper T cells; in addition, they no longer express surface Ig or surface MHC class II; they are tailored to secrete antibody at high rates
synonym: "plasma cell abnormalities" EXACT []
is_a: MT:0002144 ! B lymphocyte development

[Term]
id: MT:0002440
name: memory B cell morphology/development
namespace: Trait.ontology
def: "anomalous structure, differentiation, or number of cells of the B lymphocyte lineage that do not secrete antibody after an initial contact with antigen, but can be rapidly activated after a second challenge with the same antigen" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "memory B cell abnormalities" EXACT []
synonym: "memory B-cell abnormalities" EXACT []
is_a: MT:0002144 ! B lymphocyte development

[Term]
id: MT:0002441
name: granulocyte morphology/development
namespace: Trait.ontology
def: "anomalous structure, differentiation, or number of leukocytes that have abundant granules in the cytoplasm: basophils, neutrophils, or eosinophils" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_pig
synonym: "granulocyte abnormalities" EXACT []
is_a: MT:0001601 ! myelopoiesis

[Term]
id: MT:0002442
name: leukocyte physiology
namespace: Trait.ontology
def: "abnormal function of any of the white blood cells (basophils, eosinophils, neutrophils, lymphocytes, or monocytes)" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_pig
synonym: "leukocyte dysfunction" EXACT []
is_a: MT:0001819 ! immune cell physiology
is_a: MT:0002420 ! adaptive immunity
is_a: MT:0002421 ! cell-mediated immunity

[Term]
id: MT:0002443
name: eosinophil morphology/development
namespace: Trait.ontology
def: "anomalous structure, differentiation or number of the granular leukocytes having a two-lobed nucleus and cytoplasm containing coarse, round granules that are uniform in size and stainable by eosin" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "eosinophil abnormalities" EXACT []
is_a: MT:0002414 ! myeloblast morphology/development
is_a: MT:0002441 ! granulocyte morphology/development

[Term]
id: MT:0002444
name: T cell physiology
namespace: Trait.ontology
def: "anomalous response of T lymphocytes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_pig
synonym: "abnormal T cell function" EXACT []
synonym: "abnormal T lymphocyte function" EXACT []
synonym: "t lymphocyte dysfunction" EXACT []
synonym: "T-cell dysfunction" EXACT []
is_a: MT:0003945 ! lymphocyte physiology

[Term]
id: MT:0002445
name: mononuclear leukocyte morphology/development
namespace: Trait.ontology
def: "anomalous structure, differentiation, or number of either of the mature lymphocytes or monocytes found in the blood" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_pig
synonym: "mononuclear leukocyte abnormalities" EXACT []
is_a: MT:0002414 ! myeloblast morphology/development
is_a: MT:0005460 ! leukopoiesis

[Term]
id: MT:0002446
name: macrophage morphology/development
namespace: Trait.ontology
def: "anomalous structure, number, or composition of the large mononuclear phagocytic cells found in most tissues of the body" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "macrophage abnormalities" EXACT []
synonym: "mononuclear phagocyte abnormalities" EXACT []
is_a: MT:0002620 ! monocyte morphology/development

[Term]
id: MT:0002447
name: erythrocyte morphology
namespace: Trait.ontology
def: "structural anomaly of the fetal and adult cells in the blood that carry oxygen, red blood cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "erythrocyte abnormalities" EXACT []
synonym: "red blood cell abnormalities" EXACT []
is_a: MT:0002124 ! red blood cell
is_a: MT:0002424 ! reticulocyte morphology/development

[Term]
id: MT:0002449
name: immune cell development
namespace: Trait.ontology
def: "atypical formation of the cells of the immune system" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_pig
synonym: "immune cell developmental abnormalities" EXACT []
is_a: MT:0000716 ! immune system cell morphology

[Term]
id: MT:0002450
name: lymph organ development
namespace: Trait.ontology
def: "anomaly in the process of morphological maturation of the organs of the lymph system" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "lymph organ developmental abnormalities" EXACT []
is_a: MT:0002722 ! immune system organ morphology

[Term]
id: MT:0002451
name: macrophage physiology
namespace: Trait.ontology
def: "abnormal function or response of the phagocytic leukocytes involved in innate immunity, early non-adaptive phases of host-defense, antigen presentation, and which act as effector cells in humoral and cell-mediated immunity" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "macrophage dysfunction" EXACT []
is_a: MT:0002442 ! leukocyte physiology

[Term]
id: MT:0002452
name: antigen presenting cell physiology
namespace: Trait.ontology
def: "impairment or abnormality of the function of cells involved in making antigen recognizable by lymphocytes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "antigen presenting cell dysfunction" EXACT []
is_a: MT:0001835 ! antigen presentation
is_a: MT:0002420 ! adaptive immunity
is_a: MT:0002421 ! cell-mediated immunity

[Term]
id: MT:0002453
name: B lymphocyte antigen presentation
namespace: Trait.ontology
def: "impairment in the ability of B lymphocyte to process and/or present antigen" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "B cell antigen presentation abnormalities" EXACT []
synonym: "lymphocyte antigen presentation dysfunction" EXACT []
is_a: MT:0002452 ! antigen presenting cell physiology

[Term]
id: MT:0002454
name: macrophage antigen presentation
namespace: Trait.ontology
def: "impairment of these phagocytic cells to process and present antigen to T lymphocytes" [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "macrophage antigen presentation dysfunction" EXACT []
is_a: MT:0002451 ! macrophage physiology
is_a: MT:0002452 ! antigen presenting cell physiology

[Term]
id: MT:0002455
name: dendritic cell antigen presentation
namespace: Trait.ontology
def: "impairment of these specialized cells to process and present antigen to T lymphocytes" [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "dendritic cell antigen presentation dysfunction" EXACT []
is_a: MT:0002376 ! dendritic cell physiology
is_a: MT:0002452 ! antigen presenting cell physiology

[Term]
id: MT:0002456
name: Langerhans cell antigen presentation
namespace: Trait.ontology
def: "impairment of phagocytic cells of the epidermis to display antigen for recognition by T lymphocytes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "interdigitating reticular cell antigen presentation dysfunction" EXACT []
synonym: "Langerhans cell antigen presentation dysfunction" EXACT []
is_a: MT:0002455 ! dendritic cell antigen presentation
is_a: MT:0005362 ! Langerhans cell physiology

[Term]
id: MT:0002458
name: B cell number
namespace: Trait.ontology
def: "count of cells that are formed in the bone marrow, migrate to the peripheral lymphatic system, and mature into plasma cells or memory cells; these cells are involved in humoral immunity " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "B lymphocyte number" EXACT []
synonym: "B-cell number" EXACT []
is_a: MT:0000717 ! lymphocyte number
is_a: MT:0002144 ! B lymphocyte development

[Term]
id: MT:0002459
name: B cell physiology
namespace: Trait.ontology
def: "abnormal function of B lymphocytes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_pig
synonym: "B cell dysfunction" EXACT []
synonym: "B lymphocyte dysfunction" EXACT []
synonym: "B lymphocyte functional anomalies" EXACT []
synonym: "B-cell dysfunction" EXACT []
is_a: MT:0003945 ! lymphocyte physiology

[Term]
id: MT:0002462
name: granulocyte physiology
namespace: Trait.ontology
def: "functional anomaly of neutrophils, eosinophils, or basophils " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "granulocyte dysfunction" EXACT []
is_a: MT:0002442 ! leukocyte physiology

[Term]
id: MT:0002463
name: neutrophil physiology
namespace: Trait.ontology
def: "abnormal function of these granular leukocytes, which stain with neutral dyes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "neutrophil dysfunction" EXACT []
is_a: MT:0002462 ! granulocyte physiology

[Term]
id: MT:0002464
name: basophil physiology
namespace: Trait.ontology
def: "abnormal function of the leukocyte that contains granules that stain with basic dyes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "basophil dysfunction" EXACT []
is_a: MT:0002462 ! granulocyte physiology

[Term]
id: MT:0002465
name: eosinophil physiology
namespace: Trait.ontology
def: "abnormal function of the leukocyte that stains with eosin and is involved in clearance of parasitic infections and in allergic reactions " [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "eosinophil dysfunction" EXACT []
is_a: MT:0002462 ! granulocyte physiology

[Term]
id: MT:0002467
name: neutrophil phagocytosis
namespace: Trait.ontology
def: "reduced ability of these leukocytes to internalize particulate matter" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
is_a: MT:0002463 ! neutrophil physiology
is_a: MT:0002488 ! phagocytic cell physiology

[Term]
id: MT:0002468
name: complement physiology
namespace: Trait.ontology
def: "abnormal function of the set of plasma proteins that act together to attack extracellular pathogens" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "complement dysfunction" EXACT []
is_a: MT:0001800 ! humoral immune response
is_a: MT:0002419 ! innate immunity
is_a: MT:0002723 ! immune serum protein physiology

[Term]
id: MT:0002469
name: C1 physiology
namespace: Trait.ontology
def: "abnormal function of the complement protein, C1" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "C1 dysfunction" EXACT []
is_a: MT:0001804 ! complement protein physiology

[Term]
id: MT:0002470
name: C2 physiology
namespace: Trait.ontology
def: "abnormal function of the complement protein, C2" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "C2 dysfunction" EXACT []
is_a: MT:0001804 ! complement protein physiology

[Term]
id: MT:0002471
name: complement cascade
namespace: Trait.ontology
def: "impaired ability of the complement proteins to act in concert and attack extracellular pathogens" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "complement cascade dysfunction" EXACT []
is_a: MT:0002468 ! complement physiology

[Term]
id: MT:0002472
name: complement alternative pathway function
namespace: Trait.ontology
def: "abnormal function of the plasma protein cascade triggered by direct contact with pathogen surfaces" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
is_a: MT:0002471 ! complement cascade

[Term]
id: MT:0002473
name: complement classical pathway function
namespace: Trait.ontology
def: "abnormal function of the plasma protein cascade triggered by antigen:antibody complexes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
is_a: MT:0002471 ! complement cascade

[Term]
id: MT:0002474
name: C3 physiology
namespace: Trait.ontology
def: "abnormal function of the complement protein, C3" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "C3 dysfunction" EXACT []
is_a: MT:0001804 ! complement protein physiology

[Term]
id: MT:0002475
name: C4 physiology
namespace: Trait.ontology
def: "abnormal function of the complement protein, C4" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "C4 dysfunction" EXACT []
is_a: MT:0001804 ! complement protein physiology

[Term]
id: MT:0002476
name: C5 physiology
namespace: Trait.ontology
def: "abnormal function of the complement protein, C5" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "C5 dysfunction" EXACT []
is_a: MT:0001804 ! complement protein physiology

[Term]
id: MT:0002477
name: C6 physiology
namespace: Trait.ontology
def: "abnormal function of the complement protein, C6" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "C6 dysfunction" EXACT []
is_a: MT:0001804 ! complement protein physiology

[Term]
id: MT:0002478
name: C7 physiology
namespace: Trait.ontology
def: "abnormal function of the complement protein, C7" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "C7 dysfunction" EXACT []
is_a: MT:0001804 ! complement protein physiology

[Term]
id: MT:0002479
name: C8 physiology
namespace: Trait.ontology
def: "abnormal function of the complement protein, C8" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "C8 dysfunction" EXACT []
is_a: MT:0001804 ! complement protein physiology

[Term]
id: MT:0002480
name: C9 physiology
namespace: Trait.ontology
def: "abnormal function of the complement protein, C9" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "C9 dysfunction" EXACT []
is_a: MT:0001804 ! complement protein physiology

[Term]
id: MT:0002481
name: factor B physiology
namespace: Trait.ontology
def: "abnormal function of the complement protein, factor B" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "Bf abnormalities" EXACT []
synonym: "factor B dysfunction" EXACT []
is_a: MT:0001804 ! complement protein physiology

[Term]
id: MT:0002482
name: factor D physiology
namespace: Trait.ontology
def: "abnormal function of the complement protein, factor D" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "factor D dysfunction" EXACT []
is_a: MT:0001804 ! complement protein physiology

[Term]
id: MT:0002483
name: acute phase protein physiology
namespace: Trait.ontology
def: "functional anomaly in the series of proteins found in the blood shortly after infection and which participate in the early phases of host defense against infection" [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "acute phase protein dysfunction" EXACT []
is_a: MT:0002419 ! innate immunity
is_a: MT:0002723 ! immune serum protein physiology

[Term]
id: MT:0002484
name: C-reactive protein physiology
namespace: Trait.ontology
def: "anomaly in the function of this plasma protein that normally circulates in increased amounts during inflammation or after tissue damage" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "C-reactive protein dysfunction" EXACT []
is_a: MT:0002483 ! acute phase protein physiology

[Term]
id: MT:0002485
name: mannose-binding protein physiology
namespace: Trait.ontology
def: "an anomaly in the function of this acute phase protein that normally opsonizes pathogens bearing mannose on their surfaces and can activate the complement system" [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "mannose-binding protein dysfunction" EXACT []
is_a: MT:0002483 ! acute phase protein physiology

[Term]
id: MT:0002486
name: serum amyloid protein physiology
namespace: Trait.ontology
def: "functional anomaly in a serum protein believed to be a precursor to amyloid protein; it is present in very high levels during acute inflammatory episodes" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "serum amyloid protein dysfunction" EXACT []
is_a: MT:0002483 ! acute phase protein physiology

[Term]
id: MT:0002487
name: fibrinogen physiology
namespace: Trait.ontology
def: "an anomaly in the function of this coaguable protein in the blood plasma" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "fibrinogen dysfunction" EXACT []
is_a: MT:0002483 ! acute phase protein physiology
is_a: MT:0002551 ! blood coagulation

[Term]
id: MT:0002488
name: phagocytic cell physiology
namespace: Trait.ontology
def: "anomaly in the ability of these cells to ingest and internalize particulate matter" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "phagocytic cell dysfunction" EXACT []
is_a: MT:0002419 ! innate immunity

[Term]
id: MT:0002490
name: circulating immunoglobulin concentration
namespace: Trait.ontology
alt_id: MT:0001810
def: "deviation from the normal levels of glycoproteins present in the blood and other tissue, often functioning as antibodies" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_pig
synonym: "abnormal immunoglobulin concentration" EXACT []
synonym: "abnormal serum immunoglobulin concentration" EXACT []
synonym: "Abnormal Serum Level of Immunoglobulin" EXACT []
is_a: MT:0001800 ! humoral immune response
is_a: MT:0002459 ! B cell physiology
is_a: MT:0002723 ! immune serum protein physiology

[Term]
id: MT:0002491
name: circulating IgD level
namespace: Trait.ontology
def: "less than normal immunoglobulin class D level" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002490 ! circulating immunoglobulin concentration

[Term]
id: MT:0002492
name: circulating IgE level
namespace: Trait.ontology
def: "less than normal immunoglobulin class E level" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002490 ! circulating immunoglobulin concentration

[Term]
id: MT:0002498
name: acute inflammation
namespace: Trait.ontology
def: "aberrant early and often transient reaction of the microcirculation, characterized by movement of fluid and leukocytes from the blood into extravascular tissues; initiated by injury, infection, or local immune response " [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7, Pathology:ISBN 0-397-51047-0]
comment: characterized by: accumulation of fluid and plasma components in the affected tissue, intravascular stimulation of platelets, presence of polymorphonuclear leukocytes, cwg
synonym: "acute inflammation" EXACT []
is_a: MT:0001845 ! inflammatory response

[Term]
id: MT:0002499
name: chronic inflammation
namespace: Trait.ontology
def: "persistent inflammatory response, often caused by persistent infection or during an autoimmune response" [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
comment: characterized by: lymphocytes, plasma cells, and macrophages, cwg
is_a: MT:0001845 ! inflammatory response

[Term]
id: MT:0002500
name: granulomatous inflammation
namespace: Trait.ontology
def: "chronic inflammation resulting from the failure of the acute inflammatory response and persistence of the injurious agent; characterized by a central area of macrophages, often fused into giant cells, and surrounded by T cells " [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7, Pathology:ISBN 0-397-51047-0]
is_a: MT:0002499 ! chronic inflammation

[Term]
id: MT:0002501
name: inflammatory mediator physiology
namespace: Trait.ontology
def: "functional anomaly of any of the endogenous compounds that mediate the local accumulation of fluid, plasma proteins, and leukocytes at the site of injury, insult, or infection" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
subset: slim_pig
synonym: "inflammatory mediators" EXACT []
is_a: MT:0001845 ! inflammatory response
is_a: MT:0002723 ! immune serum protein physiology

[Term]
id: MT:0002502
name: vasoactive mediator physiology
namespace: Trait.ontology
def: "functional of any of the endogenous compounds that act on the vasculature" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0000249 ! blood vessel physiology

[Term]
id: MT:0002503
name: histamine physiology
namespace: Trait.ontology
def: "functional anomaly of this amine that is involved in local immune response, in regulating physiological function in the gut, and that acts as a neurotransmitter" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
comment: orig definition: functional anomaly of this potent vasoactive peptide stored in mast cells; it is normally released by antigen binding to IgE and results in dilation of local blood vessels and smooth muscle cell contraction; moved from immune system to homeostasis since this involves more than just immune system.
is_a: MT:0001764 ! homeostasis

[Term]
id: MT:0002504
name: serotonin activity
namespace: Trait.ontology
def: "function of this biochemical messenger and regulator, found in the CNS, gastrointestinal tract, and produced by platelets; it normally mediates neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "5-HT physiology" EXACT []
is_a: MT:0002206 ! CNS synaptic transmission
is_a: MT:0002502 ! vasoactive mediator physiology

[Term]
id: MT:0002505
name: bradykinin activity
namespace: Trait.ontology
def: "function of this potent, short-lived vasoactive peptide that causes arteriolar dilation and increased capillary permeability" [ISBN:0-397-51047-0 "Rubin E & Farber, JL (ed) Pathology"]
is_a: MT:0002502 ! vasoactive mediator physiology

[Term]
id: MT:0002506
name: anaphylotoxin activity
namespace: Trait.ontology
def: "function of any of the small fragments of complement proteins released by cleavage during complement activation, they are chemotactic and vasoactive" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0002502 ! vasoactive mediator physiology

[Term]
id: MT:0002507
name: C4a activity
namespace: Trait.ontology
def: "function of complement fragment C4a, which is normally involved in increasing vascular permeability and enhancing smooth muscle contraction" [ISBN:0-397-51047-0 "Rubin E & Farber, JL (ed) Pathology", MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"]
is_a: MT:0002506 ! anaphylotoxin activity

[Term]
id: MT:0002508
name: C5a activity
namespace: Trait.ontology
def: "function of this product of complement activation that is a potent chemotactic factor for neutrophils, monocytes, and basophils and enhances smooth muscle contraction and vascular permeability" [ISBN:0-397-51047-0 "Rubin E & Farber, JL (ed) Pathology", MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"]
is_a: MT:0002506 ! anaphylotoxin activity
is_a: MT:0002523 ! chemotactic complement factor physiology

[Term]
id: MT:0002509
name: C3a activity
namespace: Trait.ontology
def: "function of complement fragment C3a, which is normally involved in increasing vascular permeability and enhancing smooth muscle contraction" [ISBN:0-397-51047-0 "Rubin E & Farber, JL (ed) Pathology", MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"]
is_a: MT:0002506 ! anaphylotoxin activity

[Term]
id: MT:0002510
name: leukotriene activity
namespace: Trait.ontology
def: "function of any of a family of mediators derived from arachadonic acid which normally stimulate smooth muscle contraction, increase vascular permeability, and may be chemoattractants for inflammatory cells" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0002502 ! vasoactive mediator physiology

[Term]
id: MT:0002511
name: LTC4 activity
namespace: Trait.ontology
def: "function of this member of a family of mediators derived from arachadonic acid that normally stimulates smooth muscle contraction, increases vascular permeability, and may be chemoattractant for inflammatory cells" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "leukotriene C4 physiology" EXACT []
is_a: MT:0002510 ! leukotriene activity

[Term]
id: MT:0002512
name: LTD4 activity
namespace: Trait.ontology
def: "function of this member of a family of mediators derived from arachadonic acid that normally stimulates smooth muscle contraction, increases vascular permeability, and may be chemoattractant for inflammatory cells" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "leukotriene D4 physiology" EXACT []
is_a: MT:0002510 ! leukotriene activity

[Term]
id: MT:0002513
name: LTE4 activity
namespace: Trait.ontology
def: "function of this member of a family of mediators derived from arachadonic acid that normally stimulates smooth muscle contraction, increases vascular permeability, and may be chemoattractant for inflammatory cells" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "leukotriene E4 physiology" EXACT []
is_a: MT:0002510 ! leukotriene activity

[Term]
id: MT:0002514
name: prostaglandin activity
namespace: Trait.ontology
def: "function of any of a class of mediators with effects of vasodilation, vasoconstriction, and smooth muscle stimulation" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0002502 ! vasoactive mediator physiology

[Term]
id: MT:0002516
name: PGE2 activity
namespace: Trait.ontology
def: "function of this member of the prostaglandin family, which normally has vasodilatory effects, increasing vascular permeability" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "prostaglandin E2 physiology" EXACT []
is_a: MT:0002514 ! prostaglandin activity

[Term]
id: MT:0002517
name: PGI2 activity
namespace: Trait.ontology
def: "function of this member of the prostaglandin family that normally has vasodilatory effects, increasing vascular permeability" [ISBN:0-397-51047-0 "Rubin E & Farber, JL (ed) Pathology"]
synonym: "prostacyclin physiology" EXACT []
synonym: "prostaglandin I2 physiology" EXACT []
is_a: MT:0002514 ! prostaglandin activity

[Term]
id: MT:0002518
name: PGF2alpha activity
namespace: Trait.ontology
def: "function of this prostaglandin that normally has vasocontractile, oxytocic, luteolytic, and abortifacient activities" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "prostaglandin F2alpha physiology" EXACT []
is_a: MT:0002514 ! prostaglandin activity

[Term]
id: MT:0002519
name: thromboxane activity
namespace: Trait.ontology
def: "function of any of the members of a family of mediators with vasoactive effects" [MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"]
synonym: "TxB2 physiology" EXACT []
is_a: MT:0002502 ! vasoactive mediator physiology

[Term]
id: MT:0002520
name: TxA2 activity
namespace: Trait.ontology
def: "function of this potent vasoconstrictor that also mediates platelet aggregation" [ISBN:0-397-51047-0 "Rubin E & Farber, JL (ed) Pathology"]
synonym: "thromboxane A2 physiology" EXACT []
is_a: MT:0002519 ! thromboxane activity

[Term]
id: MT:0002521
name: platelet activating factor activity
namespace: Trait.ontology
def: "function of this mediator generated by nearly all activated inflammatory cells, endothelial cells, and injured tissue cells; normally it is a potent vasodilator and enhances microvasculature permeability, in addition, it induces platelet aggregation and degranulation at sites of injury and enhances the release of serotonin" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "PAF physiology" EXACT []
is_a: MT:0002502 ! vasoactive mediator physiology

[Term]
id: MT:0002522
name: chemotactic factor physiology
namespace: Trait.ontology
def: "functional anomaly of any of a class of pro-inflammatory proteins that attract and activate leukocytes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology:ISBN 0-397-51047-0]
synonym: "chemotactic factors" EXACT []
is_a: MT:0002501 ! inflammatory mediator physiology

[Term]
id: MT:0002523
name: chemotactic complement factor physiology
namespace: Trait.ontology
def: "functional anomaly of any of a subset of complement fragments that are involved in recruitment of leukocytes to the site of injury " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "chemotactic complement factors" EXACT []
is_a: MT:0002522 ! chemotactic factor physiology

[Term]
id: MT:0002525
name: LTB4 physiology
namespace: Trait.ontology
def: "functional anomaly of this product of inflammatory cell activation that is a potent chemoattractant for macrophages and neutrophils" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology:ISBN 0-397-51047-0]
synonym: "abnormal leukotriene B4 physiology" EXACT []
is_a: MT:0005467 ! chemotactic leukotriene physiology

[Term]
id: MT:0002526
name: chemokine physiology
namespace: Trait.ontology
def: "functional anomaly of any of the class of pro-inflammatory cytokines that attract and activate leukocytes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "chemokines" EXACT []
is_a: MT:0002522 ! chemotactic factor physiology

[Term]
id: MT:0002527
name: IL-8 physiology
namespace: Trait.ontology
def: "functional anomaly of this protein secreted by macrophages and is chemotactic for neutrophils and T cells" [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "abnormal interleukin-8 physiology" EXACT []
is_a: MT:0002529 ! interleukin physiology
is_a: MT:0005050 ! chemotactic interleukin physiology

[Term]
id: MT:0002528
name: IL-1 physiology
namespace: Trait.ontology
def: "functional anomaly of this soluble factor produced by macrophages/monocytes that activates vascular endothelium and lymphocytes" [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "abnormal interleukin-1 physiology" EXACT []
is_a: MT:0002529 ! interleukin physiology

[Term]
id: MT:0002529
name: interleukin physiology
namespace: Trait.ontology
def: "functional anomaly of any of the cytokines produced by leukocytes" [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
subset: slim_pig
synonym: "abnormal lymphokines physiology" EXACT []
is_a: MT:0005049 ! cytokine physiology

[Term]
id: MT:0002530
name: TNF physiology
namespace: Trait.ontology
def: "functional anomaly of this cytokine produced by macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium " [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "abnormal cachectin physiology" EXACT []
synonym: "abnormal tumor necrosis factor alpha physiology" EXACT []
is_a: MT:0005049 ! cytokine physiology

[Term]
id: MT:0002531
name: type I hypersensitivity reaction
namespace: Trait.ontology
def: "a reaction manifested by localized or generalized reaction that occurs immediately (minutes) after exposure to an antigen to which the person/animal was previously sensitized; it is IgE-mediated, and mast cell activation and degranulation are hallmarks" [Pathology_2nd edition:ISBN 0-397-51047-0]
comment: examples: hay fever, asthma, anaphylaxis
synonym: "anaphylaxis" EXACT []
synonym: "immediate type hypersensitivity" EXACT []
is_a: MT:0002148 ! immune system: hypersensitivity

[Term]
id: MT:0002532
name: type II hypersensitivity reaction
namespace: Trait.ontology
def: "response caused by an Ag-Ab reaction; antibodies are directly or indirectly cytotoxic to antigens on cell surfaces or in connective tissues; most often involves IgG and IgM; complement activation is usually involved" [Pathology_2nd edition:ISBN 0-397-51047-0]
comment: examples: autoimmune diseases: autoimmune hemolytic anemias, antibody-dependent cellular cytotoxicity (ADCC), Goodpasture disease, myasthenia gravis, Graves disease, pemphigous, pemphigoid
synonym: "antibody-mediated cellular toxicity" EXACT []
synonym: "cytotoxic type hypersensitivity" EXACT []
is_a: MT:0002148 ! immune system: hypersensitivity

[Term]
id: MT:0002533
name: type III hypersensitivity reaction
namespace: Trait.ontology
def: "tissue injury mediated by immune complexes; generally involves immune complexes formed in the blood via Abs encountering circulating Ag; Ag-Ab complexes then deposit in tissues (especially blood vessels and glomeruli), induce complement activation, and result in tissue injury" [Pathology_2nd edition:ISBN 0-397-51047-0]
comment: Examples: Autoimmune diseases: systemic lupus erythmatosus (SLE), rheumatoid arthritis, sjogren syndrome, scleroderma glomerulonephritis
synonym: "immune complex mediated hypersensitivity" EXACT []
is_a: MT:0002148 ! immune system: hypersensitivity

[Term]
id: MT:0002534
name: type IV hypersensitivity reaction
namespace: Trait.ontology
def: "an antigen-elicited cellular immune reaction that results in tissue damage, but does not require Ab participation; the response is seen at the area of contact" [Pathology_2nd edition:ISBN 0-397-51047-0]
comment: Examples: granulomatous diseases: tuberculosis, sarcoidosis. contact dermatitis: elicited by poison ivy, detergents, clothing, etc.
synonym: "cell-mediated hypersensitivity" EXACT []
synonym: "contact hypersensitivity" EXACT []
synonym: "delayed type hypersensitivity" EXACT []
is_a: MT:0002148 ! immune system: hypersensitivity

[Term]
id: MT:0002535
name: combined T cell/ B cell deficiency
namespace: Trait.ontology
def: "defective or absent host defense involving both B and T cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "combined T-cell/B-cell deficiency" EXACT []
is_a: MT:0001791 ! immunodeficiency

[Term]
id: MT:0002536
name: severe combined immunodeficiency disease
namespace: Trait.ontology
def: "rare congenital disorder characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "SCID" EXACT []
is_a: MT:0001800 ! humoral immune response
is_a: MT:0002421 ! cell-mediated immunity
is_a: MT:0002535 ! combined T cell/ B cell deficiency

[Term]
id: MT:0002539
name: B cell deficiency
namespace: Trait.ontology
def: "defective or absent host defense involving B cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "B-cell deficiency" EXACT []
synonym: "deficiency of antibody immunity" EXACT []
is_a: MT:0001791 ! immunodeficiency

[Term]
id: MT:0002540
name: congenital X-linked infantile hypogammaglobulinemia
namespace: Trait.ontology
def: "an immunologic deficiency state characterized by very low level of generally all classes of gamma-immunoglobulins " [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0001805 ! circulating IgG level

[Term]
id: MT:0002541
name: selective IgA deficiency
namespace: Trait.ontology
def: "an immunologic deficiency state characterized by very low levels of the immunoglobulin class A" [OMIM:Online Mendelian Inheritance in Man]
is_a: MT:0002539 ! B cell deficiency

[Term]
id: MT:0002543
name: phalanx length
namespace: Trait.ontology
def: "abnormally short phalanges" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005306 ! phalanx morphology

[Term]
id: MT:0002544
name: digit length
namespace: Trait.ontology
def: "abnormally short digits" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002110 ! digit morphology

[Term]
id: MT:0002546
name: synchronization of pupil reflex
namespace: Trait.ontology
is_a: MT:0002638 ! pupillary reflex

[Term]
id: MT:0002551
name: blood coagulation
namespace: Trait.ontology
alt_id: MT:0000210
alt_id: MT:0001582
def: "altered ability or inability of the blood to clot" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: pslim term
synonym: "abnormal clotting" EXACT []
synonym: "hematology: abnormal blood coagulation" EXACT []
xref: MGI:2173585
is_a: MT:0001764 ! homeostasis

[Term]
id: MT:0002557
name: social/conspecific interaction
namespace: Trait.ontology
alt_id: MT:0001351
subset: slim_cattle
subset: slim_chkn
synonym: "abnormal social behavior" EXACT []
synonym: "abnormal socialization" EXACT []
synonym: "neurological/behavioral: social/conspecific interaction anomalies" EXACT []
is_a: MT:0005386 ! behavior/neurological trait

[Term]
id: MT:0002558
name: circadian period
namespace: Trait.ontology
is_a: MT:0001502 ! circadian rhythm

[Term]
id: MT:0002559
name: circadian persistence
namespace: Trait.ontology
is_a: MT:0001502 ! circadian rhythm

[Term]
id: MT:0002561
name: circadian phase
namespace: Trait.ontology
is_a: MT:0001502 ! circadian rhythm

[Term]
id: MT:0002566
name: sexual interaction
namespace: Trait.ontology
alt_id: MT:0001369
alt_id: MT:0001370
alt_id: MT:0001374
def: "altered initiation, failure of initiation or incomplete mating behavior" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal breeding" EXACT []
synonym: "abnormal breeding/mating" EXACT []
synonym: "abnormal mating" EXACT []
is_a: MT:0002557 ! social/conspecific interaction

[Term]
id: MT:0002568
name: response to addictive substances
namespace: Trait.ontology
synonym: "neurological/behavioral: addiction/drug abuse" EXACT []
is_a: MT:0005386 ! behavior/neurological trait

[Term]
id: MT:0002572
name: emotion/affect behavior
namespace: Trait.ontology
subset: slim_chkn
subset: slim_pig
is_a: MT:0005386 ! behavior/neurological trait

[Term]
id: MT:0002574
name: vertical activity level
namespace: Trait.ontology
is_a: MT:0001399 ! activity level

[Term]
id: MT:0002576
name: enamel morphology
namespace: Trait.ontology
def: "malformation of the hard outer coating of the exposed portion of the tooth" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:71126, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal enamel" EXACT []
is_a: MT:0003930 ! tooth hard tissue morphology

[Term]
id: MT:0002578
name: ability to fire action potentials
namespace: Trait.ontology
def: "anomaly resulting in reduced changes in membrane potentials occurring in nerve or other excitable tissue when excitation occurs" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:51377]
is_a: MT:0005402 ! action potential

[Term]
id: MT:0002579
name: secondary lens fiber morphology
namespace: Trait.ontology
def: "deformation or misalignment of the elongated cells that form the crystalline lens" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:70385, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002840 ! lens fiber morphology

[Term]
id: MT:0002580
name: duodenal lesions
namespace: Trait.ontology
def: "any pathological change in the structure of the wall of the duodenum" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:70183]
is_a: MT:0003271 ! duodenum morphology

[Term]
id: MT:0002581
name: ileum morphology
namespace: Trait.ontology
def: "malformation of the portion of the small intestine that extends from the jejunum to the colon" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:70183, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal ileum" EXACT []
is_a: MT:0000496 ! small intestine morphology

[Term]
id: MT:0002582
name: disorganized extraembryonic tissue
namespace: Trait.ontology
def: "a lack of the regular arrangement of the membranes involved with the embryo's protection and nutrition" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:40596]
is_a: MT:0002086 ! extraembryonic tissue morphology

[Term]
id: MT:0002585
name: response/metabolism to xenobiotics
namespace: Trait.ontology
def: "altered ability or inability to metabolize or respond to foreign substances" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:55555]
synonym: "abnormal metabolism of xenobiotics" EXACT []
is_a: MT:0002121 ! metabolism

[Term]
id: MT:0002586
name: platelet volume
namespace: Trait.ontology
def: "anomaly in the content of platelet cells over normal" [cml:Cathleen M. Lutz_Mouse Genome Informatics Curator]
is_a: MT:0000228 ! thrombopoiesis

[Term]
id: MT:0002594
name: mean erythrocyte count
namespace: Trait.ontology
def: "less than average numbers of red blood cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "low mean RBC count" EXACT []
synonym: "low mean red blood cell count" EXACT []
is_a: MT:0001586 ! erythrocyte count

[Term]
id: MT:0002596
name: hematocrit
namespace: Trait.ontology
alt_id: MT:0000206
alt_id: MT:0001578
def: "greater or less than the average percentage of a volume of a blood sample occupied by red blood cells" [MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_cattle
subset: slim_chkn
synonym: "hematocrit traits" EXACT []
synonym: "packed cell volume" EXACT []
is_a: MT:0002124 ! red blood cell

[Term]
id: MT:0002599
name: mean platelet volume
namespace: Trait.ontology
def: "increased content of platelet cells over normal" [cml:Cathleen M. Lutz_Mouse Genome Informatics Curator]
synonym: "high mean platelet volume" EXACT []
is_a: MT:0002586 ! platelet volume

[Term]
id: MT:0002607
name: basophil count
namespace: Trait.ontology
def: "lower than average number of basophils as measured by the percent of the total number of leukocytes" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, MPD:Mouse Phenome Database]
synonym: "decreased basophil number" EXACT []
synonym: "low basophil count" EXACT []
is_a: MT:0000334 ! granulocyte number
is_a: MT:0002422 ! basophil morphology/development

[Term]
id: MT:0002619
name: lymphocyte morphology/development
namespace: Trait.ontology
alt_id: MT:0005063
def: "anomalous structure, differentiation, or number of the white blood cells formed in the body's lymphoid tissue" [MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_pig
synonym: "lymphocyte abnormalities" EXACT []
synonym: "lymphocyte structural abnormalities" EXACT []
is_a: MT:0002445 ! mononuclear leukocyte morphology/development

[Term]
id: MT:0002620
name: monocyte morphology/development
namespace: Trait.ontology
def: "anomalous structure, number, or development of the white blood cells that are precursors to macrophages" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "monocyte abnormalities" EXACT []
is_a: MT:0001601 ! myelopoiesis
is_a: MT:0002445 ! mononuclear leukocyte morphology/development

[Term]
id: MT:0002621
name: time of neural tube closure
namespace: Trait.ontology
def: "delayed fusion of the neuroepithelial layer in early development" [cml:Cathleen M. Lutz_Mouse Genome Informatics Curator, J:79790]
synonym: "delayed spina bifida" EXACT []
is_a: MT:0003720 ! neural tube closure

[Term]
id: MT:0002622
name: cochlear hair cell morphology
namespace: Trait.ontology
def: "structure, form, organization, or number of the sensory epithelial cells of the cochlea; these cells are in synaptic contact with the auditory nerve" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000042 ! organ of Corti
is_a: MT:0000045 ! hair cell morphology
is_a: MT:0003308 ! cochlear sensory epithelium morphology

[Term]
id: MT:0002623
name: vestibular hair cell morphology
namespace: Trait.ontology
def: "form, structure, organization, or number of the sensory epithelium of the maculae and cristae of the membranous labyrinth of the internal ear; afferent and efferent nerve fibers of the vestibular nerve end synaptically on them; from the apical end of each cell a bundle of stereocilia and a kinocilium extend into the statoconial membrane of the maculae and the cupula of the cristae" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000034 ! vestibule morphology
is_a: MT:0000045 ! hair cell morphology

[Term]
id: MT:0002624
name: tricuspid valve integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the valve located between the right atrium and the right ventricle of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0002745 ! atrioventricular valve integrity
relationship: part_of MT:0000036 ! tricuspid valve morphology

[Term]
id: MT:0002625
name: left ventricle cell size
namespace: Trait.ontology
def: "the physical dimensions, proportions, magnitude, or extent of the cells in the left lower chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "left ventricular cell size" RELATED []
is_a: MT:0001625 ! heart cell size
relationship: part_of MT:0003921 ! left ventricle morphology

[Term]
id: MT:0002627
name: teratoma
namespace: Trait.ontology
def: "neoplasms composed of multiple tissue types; includes types not found in tissue in which lesion arises" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0002628
name: fatty liver
namespace: Trait.ontology
def: "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "hepatic steatosis" EXACT []
synonym: "liver adiposis" EXACT []
synonym: "liver steatosis" EXACT []
is_a: MT:0000598 ! liver morphology

[Term]
id: MT:0002629
name: activity elicited by ethanol administration
namespace: Trait.ontology
is_a: MT:0001399 ! activity level

[Term]
id: MT:0002630
name: endocochlear potential
namespace: Trait.ontology
def: "the electrical potential difference between the endolymphatic and perilymphatic compartments of the cochlea" [J:80917, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "abnormal endolymphatic potential" EXACT []
is_a: MT:0000319 ! endolymph physiology
is_a: MT:0000365 ! hearing electrophysiology
is_a: MT:0000483 ! sensorineural hearing function

[Term]
id: MT:0002631
name: epididymis morphology
namespace: Trait.ontology
def: "malformation of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "parorchis" EXACT []
is_a: MT:0001145 ! male reproductive anatomy

[Term]
id: MT:0002634
name: sensorimotor gating
namespace: Trait.ontology
def: "malfunction of the process by which inhibitory neural pathways filter multiple stimuli and allow attention to be focused on one stimulus; usually measured by pre-pulse inhibition (PPI)" [J:42758, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0002636
name: time of vaginal opening
namespace: Trait.ontology
def: "the opening of the genital canal in a female occurring at a later than expected age" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "delayed vaginal opening time" EXACT []
is_a: MT:0001938 ! time of sexual maturation

[Term]
id: MT:0002637
name: uterus size
namespace: Trait.ontology
def: "reduced size of the female muscular organ of gestation" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
subset: slim_pig
is_a: MT:0001120 ! uterus morphology

[Term]
id: MT:0002638
name: pupillary reflex
namespace: Trait.ontology
def: "change in pupil diameter as a reflex response to any stimulus" [cml:Cathleen M. Lutz_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001961 ! reflex
is_a: MT:0005253 ! eye physiology

[Term]
id: MT:0002640
name: reticulocytosis
namespace: Trait.ontology
def: "an increase in the number of reticulocytes in the blood" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:78271]
is_a: MT:0002124 ! red blood cell

[Term]
id: MT:0002641
name: anisopoikilocytosis
namespace: Trait.ontology
def: "presence in blood of RBCs of abnormal shapes and sizes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:78271]
is_a: MT:0002447 ! erythrocyte morphology

[Term]
id: MT:0002642
name: anisocytosis
namespace: Trait.ontology
alt_id: MT:0000246
alt_id: MT:0001609
def: "blood cells of variable size on smear" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:7209]
synonym: "anisocytosis" EXACT []
is_a: MT:0002641 ! anisopoikilocytosis

[Term]
id: MT:0002643
name: poikilocytosis
namespace: Trait.ontology
def: "blood cells of variable shape on smear" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:7209]
is_a: MT:0002641 ! anisopoikilocytosis

[Term]
id: MT:0002644
name: circulating triglyceride level
namespace: Trait.ontology
alt_id: MT:0005143
def: "lower than normal concentration of triacylglycerols in the blood" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
synonym: "low plasma triacylglycerol level" EXACT []
synonym: "low plasma triglyceride level" EXACT []
synonym: "low serum triacylglycerol level" EXACT []
synonym: "low serum triglyceride level" EXACT []
is_a: MT:0000187 ! triglyceride level
is_a: MT:0003949 ! circulating lipid level

[Term]
id: MT:0002645
name: cholesterol absorption
namespace: Trait.ontology
def: "anomalous ability of the body to take in these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005342 ! lipid absorption

[Term]
id: MT:0002648
name: delaminated enamel
namespace: Trait.ontology
def: "separation of the hard outer coating of the exposed portion of the tooth from the underlying hard tissue" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002576 ! enamel morphology

[Term]
id: MT:0002649
name: enamel rod pattern
namespace: Trait.ontology
def: "anomalous orientation of the structural unit of tooth enamel " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002576 ! enamel morphology

[Term]
id: MT:0002650
name: ameloblast morphology
namespace: Trait.ontology
def: "malformation of the epithelial cells of the inner layer of the enamel organ of the developing tooth" [il:Ira Lu_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal ameloblast" EXACT []
is_a: MT:0000116 ! tooth development

[Term]
id: MT:0002651
name: sciatic nerve morphology
namespace: Trait.ontology
def: "malformation, absence or misprojection of the nerve which originates in the lumbar and sacral spinal cord (L4 to S3) and supplies motor and sensory innervation to the lower extremity" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0001077 ! spinal nerve morphology

[Term]
id: MT:0002653
name: ependyma morphology
namespace: Trait.ontology
def: "malformation or absence of the cellular membrane that lines the brain ventricles and the central canal of the spinal cord" [il:Ira Lu_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal ependyma" EXACT []
is_a: MT:0002200 ! brain ventricle/choroid plexus morphology
is_a: MT:0003632 ! nervous system morphology

[Term]
id: MT:0002654
name: spongiform encephalopathy
namespace: Trait.ontology
def: "a neurodegenerative state characterized by the appearance of large vacuolated areas in the brain cells, resembling a sponge" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "spongiform degeneration" EXACT []
is_a: MT:0002229 ! neural integrity

[Term]
id: MT:0002655
name: keratinocyte morphology
namespace: Trait.ontology
def: "structural or developmental anomaly of the cells of the epidermis that produce keratin in the process of differentiating into the dead and fully keratinized cells of the stratum corneum" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001216 ! epidermal layer morphology

[Term]
id: MT:0002656
name: keratinocyte differentiation
namespace: Trait.ontology
def: "developmental anomaly of the cells of the epidermis that produce keratin in the process of differentiating into the dead and fully keratinized cells of the stratum corneum" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002655 ! keratinocyte morphology

[Term]
id: MT:0002657
name: chondrodystrophy
namespace: Trait.ontology
def: "abnormal development of the cartilage primordia of long bones, resulting in abnormally short extremities but normal head and trunk" [il:Ira Lu_Mouse Genome Informatics Curator]
synonym: "chondrodysplasia" EXACT []
is_a: MT:0000164 ! cartilage development
is_a: MT:0002113 ! skeleton development

[Term]
id: MT:0002658
name: liver regeneration
namespace: Trait.ontology
def: "deviation from the normal ability of liver to regenerate healthy tissue following partial hepatectomy" [il:Ira Lu_Mouse Genome Informatics Curator]
is_a: MT:0000598 ! liver morphology

[Term]
id: MT:0002660
name: caput morphology
namespace: Trait.ontology
def: "anomalous structure of the head of the epididymis" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002631 ! epididymis morphology

[Term]
id: MT:0002661
name: corpus morphology
namespace: Trait.ontology
def: "anomalous structure of the body of the epididymis" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002631 ! epididymis morphology

[Term]
id: MT:0002662
name: cauda morphology
namespace: Trait.ontology
def: "anomalous structure of the tail of the epididymis" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002631 ! epididymis morphology

[Term]
id: MT:0002663
name: blastocele formation
namespace: Trait.ontology
def: "developmental anomaly resulting in the absence of the cavity in the blastula of the developing embryo" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:19904, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal cavitation" EXACT []
synonym: "absent blastocoel cavity" EXACT []
synonym: "absent blastocoele" EXACT []
synonym: "failure to cavitate" EXACT []
synonym: "failure to form blastocyst cavity" EXACT []
is_a: MT:0002085 ! embryonic tissue morphology

[Term]
id: MT:0002664
name: circulating adrenocorticotropin level
namespace: Trait.ontology
def: "decreased concentration in the blood of the pituitary hormone that stimulates the secretion of adrenal cortical steroids and induces growth of the adrenal cortex" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_pig
synonym: "circulating adrenocorticotropic hormone level" EXACT []
synonym: "decreased serum levels of ACTH" EXACT []
synonym: "decreased serum levels of adrenocorticotropin" EXACT []
is_a: MT:0003966 ! adrenocorticotropin level
is_a: MT:0005116 ! circulating pituitary hormone level

[Term]
id: MT:0002668
name: circulating potassium level
namespace: Trait.ontology
def: "anomalous concentration in the blood of this alkaline metallic element, the most abundant intracellular ion; anomalies in the extracellular (circulating) concentration have important implications for the function of excitable tissues, such as nerve and muscle" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal potassium level" EXACT []
is_a: MT:0000179 ! blood chemistry
is_a: MT:0001765 ! ion homeostasis

[Term]
id: MT:0002669
name: scrotum morphology
namespace: Trait.ontology
def: "malformation of the external sac of skin that encloses the testes" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_pig
is_a: MT:0001145 ! male reproductive anatomy

[Term]
id: MT:0002671
name: belted
namespace: Trait.ontology
def: "the appearance of a stripe of white fur around the circumference of the abdomen" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002075 ! coat color

[Term]
id: MT:0002672
name: branchial arch artery integrity
namespace: Trait.ontology
alt_id: MT:0001617
alt_id: MT:0001618
def: "completion, soundness or configuration of the vessels formed within the five pairs of branchial arches in embryogenesis; in the adult, some of these vessels give rise to the great vessels" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal aortic arches" EXACT []
synonym: "abnormal branchial arch arteries" EXACT []
is_a: MT:0002884 ! branchial arches

[Term]
id: MT:0002673
name: sperm count
namespace: Trait.ontology
def: "increased or decreased numbers of spermatozoa" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
synonym: "abnormal sperm number" EXACT []
is_a: MT:0001929 ! gametogenesis

[Term]
id: MT:0002674
name: sperm motility
namespace: Trait.ontology
def: "anomalies in the mobility of the spermatozoa" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_chkn
is_a: MT:0001929 ! gametogenesis

[Term]
id: MT:0002675
name: asthenozoospermia
namespace: Trait.ontology
def: "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "asthenospermia" EXACT []
synonym: "impaired sperm motility" EXACT []
is_a: MT:0002674 ! sperm motility

[Term]
id: MT:0002679
name: corpora lutea morphology
namespace: Trait.ontology
def: "malformed or absent yellow endocrine body formed in the ovary after follicle rupture" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
subset: slim_pig
synonym: "abnormal corpus luteum" EXACT []
is_a: MT:0003356 ! luteinization

[Term]
id: MT:0002680
name: number of corpora lutea
namespace: Trait.ontology
def: "fewer than normal numbers of yellow endocrine body formed in the ovary after follicle rupture in a given oestrous cycle" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
subset: slim_pig
is_a: MT:0002679 ! corpora lutea morphology

[Term]
id: MT:0002682
name: number of mature ovarian follicles
namespace: Trait.ontology
def: "fewer than normal numbers of spheroid cell aggregations in the ovary containing the ovum" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001131 ! ovarian follicle morphology

[Term]
id: MT:0002683
name: onset of fertility
namespace: Trait.ontology
def: "age at which animals develop the ability to produce live offspring" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "age at first breeding" NARROW []
synonym: "age at first egg" NARROW []
synonym: "age at puberty" EXACT []
synonym: "age at sexual maturity" EXACT []
is_a: MT:0001937 ! sexual maturation
is_a: MT:0002161 ! fertility/fecundity

[Term]
id: MT:0002685
name: proliferation of spermatogonia
namespace: Trait.ontology
def: "reduction in the proliferation of the spermatogonial stem cells either due to reduced mitosis or increased apoptosis" [J:62271, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
is_a: MT:0001156 ! spermatogenesis

[Term]
id: MT:0002686
name: globozoospermia
namespace: Trait.ontology
def: "malformation of the acrosome resulting in a round sperm head" [J:57312, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "acrosome malformation of spermatozoa" EXACT []
synonym: "round sperm heads" EXACT []
synonym: "round-headed spermatozoa" EXACT []
is_a: MT:0001156 ! spermatogenesis
is_a: MT:0002208 ! germ cell morphology

[Term]
id: MT:0002687
name: oligozoospermia
namespace: Trait.ontology
alt_id: MT:0002684
def: "reduced concentration of spermatozoa " [J:57312, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "oligospermia" EXACT []
synonym: "reduced sperm count" EXACT []
synonym: "reduced sperm number" EXACT []
is_a: MT:0001156 ! spermatogenesis
is_a: MT:0002209 ! germ cell number
is_a: MT:0002673 ! sperm count

[Term]
id: MT:0002689
name: molar morphology
namespace: Trait.ontology
def: "structural defect of the most posterior teeth located on either side of the jaw, and characterized by a large crown and broad chewing surface" [il:Ira Lu_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal molars" EXACT []
is_a: MT:0002100 ! tooth morphology

[Term]
id: MT:0002693
name: pancreas physiology
namespace: Trait.ontology
def: "aberrant function of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal pancreas function" EXACT []
is_a: MT:0001663 ! digestive system physiology
is_a: MT:0002164 ! gland physiology

[Term]
id: MT:0002694
name: pancreas secretion
namespace: Trait.ontology
def: "altered ability of the pancreas to release its products" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002693 ! pancreas physiology

[Term]
id: MT:0002695
name: circulating glucagon level
namespace: Trait.ontology
def: "anomalous blood concentration of this peptide hormone secreted by the alpha cells of the pancreas; normally leads to a rise in plasma glucose" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal glucagon level" EXACT []
is_a: MT:0002078 ! glucose homeostasis

[Term]
id: MT:0002697
name: eye size
namespace: Trait.ontology
def: "anomalous bulk of the organ of vision" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "eye size abnormalities" EXACT []
is_a: MT:0002092 ! eye morphology

[Term]
id: MT:0002698
name: sclera morphology
namespace: Trait.ontology
def: "structural anomaly of the fibrous, outer envelope of the eyeball, covering it entirely excepting the segment covered anteriorly by the cornea " [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "sclera abnormalities" EXACT []
synonym: "sclerotic coat abnormalities" EXACT []
synonym: "sclerotica abnormalities" EXACT []
synonym: "tunica albuginea oculi abnormalities" EXACT []
synonym: "tunica sclerotica abnormalities" EXACT []
is_a: MT:0002092 ! eye morphology

[Term]
id: MT:0002699
name: vitreous body
namespace: Trait.ontology
def: "anomalies of the transparent, semigelatinous substance that fills the cavity behind the crystalline lens of the eye and in front of the retina" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "vitreous abnormalities" EXACT []
synonym: "vitreous body abnormalities" EXACT []
is_a: MT:0005195 ! posterior eye segment morphology
is_a: MT:0005299 ! eye posterior chamber

[Term]
id: MT:0002700
name: opacity of vitreous body
namespace: Trait.ontology
alt_id: MT:0001291
def: "milky or cloudy eyeball that is impervious to light" [J:30249]
synonym: "opacity of eyeball" EXACT []
is_a: MT:0002699 ! vitreous body

[Term]
id: MT:0002703
name: renal tubule morphology
namespace: Trait.ontology
def: "anomalous structure or development of the loops of Henle and collecting ducts in the kidney" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0003881 ! nephron morphology

[Term]
id: MT:0002704
name: tubular nephritis
namespace: Trait.ontology
def: "inflammation of the renal tubules" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001859 ! kidney inflammation
is_a: MT:0002703 ! renal tubule morphology

[Term]
id: MT:0002705
name: renal tubule size
namespace: Trait.ontology
def: "enlarged lumens of the loops of Henle and/or collecting ducts of the kidney" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002703 ! renal tubule morphology

[Term]
id: MT:0002706
name: kidney size
namespace: Trait.ontology
def: "anomalous physical bulk one or both of the organs responsible for urine secretion" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002135 ! kidney morphology

[Term]
id: MT:0002707
name: kidney weight
namespace: Trait.ontology
def: "anomaly in the heft of the organs responsible for urine secretion" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002706 ! kidney size

[Term]
id: MT:0002708
name: kidney stones
namespace: Trait.ontology
alt_id: MT:0002709
def: "calculi occurring in the kidney" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "kidney calcium calculi" EXACT []
is_a: MT:0005360 ! urolithiasis

[Term]
id: MT:0002713
name: glycogen catabolism
namespace: Trait.ontology
def: "inability to breakdown glycogen; or reduced or increased rate of glycogen breakdown" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal glycogenolysis" EXACT []
is_a: MT:0005438 ! glycogen homeostasis

[Term]
id: MT:0002716
name: preputial gland size
namespace: Trait.ontology
def: "reduced size of the sebaceous glands of the corona and neck of the glans penis" [il:Ira Lu_Mouse Genome Informatics Curator, J:82312, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002717 ! preputial gland morphology

[Term]
id: MT:0002717
name: preputial gland morphology
namespace: Trait.ontology
def: "anomalous structure of the sebaceous glands of the corona and neck of the glans penis" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal preputial glands" EXACT []
is_a: MT:0000653 ! sex gland morphology

[Term]
id: MT:0002718
name: inner cell mass morphology
namespace: Trait.ontology
def: "malformed or absent cells of the blastocyst that develop into the body of the embryo" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal embryoblast" EXACT []
is_a: MT:0002085 ! embryonic tissue morphology

[Term]
id: MT:0002722
name: immune system organ morphology
namespace: Trait.ontology
alt_id: MT:0000686
def: "anomalous structure/organization or development of lymphoid organs" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_chkn
synonym: "abnormal lymph organ" EXACT []
synonym: "immune system: organ abnormalities" EXACT []
is_a: MT:0000685 ! immune system morphology

[Term]
id: MT:0002723
name: immune serum protein physiology
namespace: Trait.ontology
def: "abnormal concentration or function of circulating immune proteins" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_pig
synonym: "immune system: serum protein abnormalities" EXACT []
is_a: MT:0001790 ! immune system physiology

[Term]
id: MT:0002725
name: vein morphology
namespace: Trait.ontology
def: "any measurable or observable structural characterisitic of the blood vessels that carry blood towards the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "venous morphology" EXACT []
xref: MP:0002725
is_a: MT:0001614 ! blood vessel morphology

[Term]
id: MT:0002726
name: pulmonary vein morphology
namespace: Trait.ontology
def: "any measurable or observable structural characterisitic of the blood vessels that return oxygenated blood from the lungs to the left atrium of the heart" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "pulmonary venous morphology" EXACT []
is_a: MT:0002725 ! vein morphology

[Term]
id: MT:0002729
name: canal morphology
namespace: Trait.ontology
def: "any anomaly or malformation of the tubular ducts of the inner ear" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal canals" EXACT []
is_a: MT:0000026 ! inner ear morphology

[Term]
id: MT:0002731
name: megacolon
namespace: Trait.ontology
def: "extreme dilation of the colon" [J:40722, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "giant colon" EXACT []
is_a: MT:0000495 ! colon morphology

[Term]
id: MT:0002732
name: trichoepithelioma
namespace: Trait.ontology
def: "benign hair follicle tumors that lack mature hair follicles, derived from basal cells of the hair follicles enclosing small keratin cysts" [il:Ira Lu_Mouse Genome Informatics Curator]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0002733
name: thermal nociception
namespace: Trait.ontology
alt_id: MT:0001972
is_a: MT:0001968 ! touch/ nociception

[Term]
id: MT:0002734
name: mechanical nociception
namespace: Trait.ontology
alt_id: MT:0002737
is_a: MT:0001968 ! touch/ nociception

[Term]
id: MT:0002735
name: chemical nociception
namespace: Trait.ontology
is_a: MT:0001968 ! touch/ nociception

[Term]
id: MT:0002739
name: olfactory bulb development
namespace: Trait.ontology
def: "abnormality in the progression of the formation of the olfactory bulb" [J:65380, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
is_a: MT:0000819 ! olfactory bulb morphology
is_a: MT:0000913 ! brain development

[Term]
id: MT:0002741
name: olfactory bulb size
namespace: Trait.ontology
def: "reduced size of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [J:79871]
is_a: MT:0000819 ! olfactory bulb morphology

[Term]
id: MT:0002743
name: glomerulonephritis
namespace: Trait.ontology
def: "glomerular disease characterized by diffuse inflammatory reaction that is not the acute response to infection of the kidneys" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "glomerular nephritis" EXACT []
is_a: MT:0000523 ! cortical glomerulopathies
is_a: MT:0001859 ! kidney inflammation

[Term]
id: MT:0002745
name: atrioventricular valve integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the valves that gate the flow of blood from the atria into the ventricles" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
comment: take out this layer
synonym: "abnormal atrioventricular valves" EXACT []
relationship: part_of MT:0000025 ! atrioventricular valve morphology
relationship: part_of MT:0000053 ! heart integrity

[Term]
id: MT:0002746
name: semilunar valve morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the valves that gate the flow of blood from the ventricles into the aorta and pulmonary trunk" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
is_a: MT:0000285 ! heart valve morphology

[Term]
id: MT:0002747
name: aortic valve integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the valve between the left ventricle and the ascending aorta" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0006049 ! semilunar valve integrity
relationship: part_of MT:0000040 ! aortic valve morphology

[Term]
id: MT:0002748
name: pulmonary valve integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the valve between the right ventricle and the pulmonary trunk" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0006049 ! semilunar valve integrity
relationship: part_of MT:0000044 ! pulmonary valve morphology

[Term]
id: MT:0002750
name: exophthalmos
namespace: Trait.ontology
def: "protrusion of one or both eyeballs" [il:Ira Lu_Mouse Genome Informatics Curator, J:47965]
synonym: "bulging eyes" EXACT []
synonym: "proptosis" EXACT []
synonym: "protruding eyes" EXACT []
is_a: MT:0006195 ! position of eyes in the eye socket

[Term]
id: MT:0002751
name: autonomic nervous system morphology
namespace: Trait.ontology
def: "any malformation or absence of neurons in the motor system for the viscera, the smooth muscles of the body or exocrine glands; includes the enteric, parasympathetic, and sympathetic nervous systems taken together" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "autonomic nervous system abnormalities" EXACT []
is_a: MT:0003632 ! nervous system morphology

[Term]
id: MT:0002752
name: somatic nervous system morphology
namespace: Trait.ontology
def: "malformation or absence of any of the cranial and spinal nerves or their ganglia or the peripheral sensory receptors" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "somatic nervous system abnormalities" EXACT []
is_a: MT:0003632 ! nervous system morphology

[Term]
id: MT:0002753
name: left ventricle size
namespace: Trait.ontology
def: "the physical dimensions, proportions, magnitude, or extent of the left lower chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "left ventricular size" RELATED []
relationship: part_of MT:0003921 ! left ventricle morphology
relationship: part_of MT:0005406 ! heart size

[Term]
id: MT:0002754
name: right ventricle size
namespace: Trait.ontology
def: "the physical dimensions, proportions, magnitude, or extent of the right lower chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
subset: slim_chkn
synonym: "right ventricular size" RELATED []
relationship: part_of MT:0003920 ! right ventricle morphology
relationship: part_of MT:0005406 ! heart size

[Term]
id: MT:0002756
name: pyramidal neuron number
namespace: Trait.ontology
def: "fewer than average number of projection neurons in the hippocampus" [cml:Cathleen M. Lutz_Mouse Genome Informatics Curator, J:82964]
synonym: "decreased pyramidal cell number" EXACT []
synonym: "reduced number of pyramidal cells" EXACT []
synonym: "reduced pyramidal cell number" EXACT []
is_a: MT:0005442 ! pyramidal neuron morphology

[Term]
id: MT:0002758
name: tail length
namespace: Trait.ontology
def: "straight line distance from the tip of the tail to the point of attachment to the body" [J:82849, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
is_a: MT:0003456 ! tail size

[Term]
id: MT:0002759
name: caudal vertebrae morphology
namespace: Trait.ontology
alt_id: MT:0000456
def: "malformed bony segments of the tail, usually 27-30 present" [J:82849, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "abnormal tail vertebrae morphology" EXACT []
is_a: MT:0000137 ! vertebrae morphology
is_a: MT:0002111 ! tail morphology
is_a: MT:0002115 ! skeleton extremities morphology

[Term]
id: MT:0002760
name: ectopic pyramidal neurons
namespace: Trait.ontology
def: "mispositioned, triangular shaped projection neurons in the hippocampus" [J:4978, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "ectopic pyramidal cells" EXACT []
synonym: "heterotopic pyramidal cells" EXACT []
is_a: MT:0005442 ! pyramidal neuron morphology

[Term]
id: MT:0002761
name: hippocampal mossy fiber morphology
namespace: Trait.ontology
def: "absence or misprojection of axons of neuronal cells in the dentate gyrus" [J:4978, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal hippocampal mossy fibers" EXACT []
is_a: MT:0000807 ! hippocampus morphology

[Term]
id: MT:0002762
name: ectopic granule cells
namespace: Trait.ontology
def: "granule cell body resides in a place other than the external or internal granule layer of the cerebellum" [J:4978]
synonym: "ectopic granule neuron" EXACT []
synonym: "heterotopic granule cells" EXACT []
is_a: MT:0004098 ! granule neuron morphology

[Term]
id: MT:0002763
name: ectopic Bergmann glia cells
namespace: Trait.ontology
def: "mispositioned astrocyte-type glia cell associated with Purkinje cells in the cerebellum" [J:4978, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "heterotopic Bergmann glia cells" EXACT []
is_a: MT:0000875 ! cerebellar Purkinje cell layer morphology
is_a: MT:0002182 ! astrocyte morphology

[Term]
id: MT:0002766
name: situs inversus
namespace: Trait.ontology
def: "lateral transposition of the viscera of the thorax and abdomen, sometimes incomplete" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "visceral inversion" EXACT []
is_a: MT:0002089 ! postnatal growth/weight/body size

[Term]
id: MT:0002767
name: situs ambiguus
namespace: Trait.ontology
def: "abnormal organ position" [J:62608]
is_a: MT:0002089 ! postnatal growth/weight/body size

[Term]
id: MT:0002769
name: vas deferens morphology
namespace: Trait.ontology
def: "malformation of the secretory duct of the testicle that carries spermatozoa, running from the epididymis, of which it is the continuation, to the prostatic urethra where it terminates to form ejaculatory duct" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001145 ! male reproductive anatomy

[Term]
id: MT:0002773
name: circulating luteinizing hormone level
namespace: Trait.ontology
def: "lower than normal levels in the bloodstream of LH, the hormone that regulates steroid production by the interstitial cells of the testis and the ovary" [J:35132, MeSH:National Library of Medicine_Medical Subject Headings, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "decreased serum levels of LH" EXACT []
synonym: "decreased serum levels of luteinizing hormone" EXACT []
synonym: "decreased serum levels of lutropin" EXACT []
is_a: MT:0003361 ! circulating gonadotropin level
is_a: MT:0003969 ! luteinizing hormone level
is_a: MT:0005116 ! circulating pituitary hormone level

[Term]
id: MT:0002778
name: meroanencephaly
namespace: Trait.ontology
def: "type of anencephaly in which the brain and cranium are present in rudimentary form" [il:Ira Lu_Mouse Genome Informatics Curator, J:33716, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001890 ! anencephaly

[Term]
id: MT:0002779
name: sex gland secretion
namespace: Trait.ontology
def: "malfunction of the production and/or release of hormones from a cell or a gland of the reproductive system " [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0005647 ! sex gland physiology

[Term]
id: MT:0002782
name: testicular secretion
namespace: Trait.ontology
def: "malfunction of the production and/or release of hormones from testicular tissue" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000051 ! testes physiology
is_a: MT:0002779 ! sex gland secretion

[Term]
id: MT:0002783
name: ovarian secretion
namespace: Trait.ontology
def: "malfunction of the production and/or release of hormones from ovarian tissue" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002779 ! sex gland secretion
is_a: MT:0003507 ! ovary physiology

[Term]
id: MT:0002784
name: Sertoli cell morphology
namespace: Trait.ontology
def: "malformation of the cells of the seminiferous tubules that create the blood-testes barrier and enable spermatogenesis" [J:65900, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "abnormal Sertoli cells" EXACT []
is_a: MT:0002216 ! seminiferous tubule morphology

[Term]
id: MT:0002785
name: Leydig cell number
namespace: Trait.ontology
def: "lack of the interstitial cells of the seminiferous tubules that secrete testosterone" [J:65900, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "absence of Leydig cells" EXACT []
is_a: MT:0001940 ! testicular cell number
is_a: MT:0002786 ! Leydig cell morphology

[Term]
id: MT:0002786
name: Leydig cell morphology
namespace: Trait.ontology
def: "malformation or absence of the interstitial cells of the seminiferous tubules that secrete testosterone" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "abnormal Leydig cells" EXACT []
is_a: MT:0002216 ! seminiferous tubule morphology

[Term]
id: MT:0002787
name: pseudohermaphroditism
namespace: Trait.ontology
def: "unambiguous gonadal sex (i.e. possesses either testes or ovaries, consistent with chromosomal sex) but has ambiguous secondary sexual characteristics" [llw2:Linda Washburn_Mouse Genome Informatics Curator, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "false hermaphroditism" EXACT []
is_a: MT:0002212 ! secondary sex determination

[Term]
id: MT:0002788
name: female pseudohermaphroditism
namespace: Trait.ontology
def: "pseudohermaphroditism in which the gonads are female (ovaries) and the karyotype is XX but the secondary sex characteristics are male-like or ambiguous" [llw2:Linda Washburn_Mouse Genome Informatics Curator, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
is_a: MT:0002787 ! pseudohermaphroditism

[Term]
id: MT:0002789
name: male pseudohermaphroditism
namespace: Trait.ontology
def: "pseudohermaphroditism in which the gonads are male (testes) and the karyotype is XY but the secondary sex characteristics are female-like or ambiguous" [llw2:Linda Washburn_Mouse Genome Informatics Curator, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
is_a: MT:0002787 ! pseudohermaphroditism

[Term]
id: MT:0002790
name: circulating follicle stimulating hormone level
namespace: Trait.ontology
def: "less than expected blood concentration of the hormone that, in females, stimulates the graafian follicles of the ovary and assists in follicular maturation and the secretion of estradiol; in the male it stimulates the epithelium of the seminiferous tubules and is partly responsible for spermatogenesis" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "decreased serum levels of follicle stimulating hormone" EXACT []
synonym: "decreased serum levels of follitropin" EXACT []
synonym: "decreased serum levels of FSH" EXACT []
synonym: "decreased serum levels of gametokinetic hormone" EXACT []
is_a: MT:0003361 ! circulating gonadotropin level
is_a: MT:0003967 ! follicle stimulating hormone level
is_a: MT:0005116 ! circulating pituitary hormone level

[Term]
id: MT:0002791
name: steatorrhea
namespace: Trait.ontology
def: "passage of large amounts of fat in the feces due to the inability to digest and absorb it" [J:75167]
is_a: MT:0001666 ! nutrient absorption
is_a: MT:0003868 ! feces composition

[Term]
id: MT:0002792
name: retina blood vessel morphology
namespace: Trait.ontology
alt_id: MT:0006189
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the blood vessels supplying the retina" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "morphology of the retinal vasculature" RELATED []
synonym: "retinal vascular morphology" RELATED []
xref: MP:0002792
is_a: MT:0001325 ! retina morphology
is_a: MT:0001614 ! blood vessel morphology

[Term]
id: MT:0002794
name: lenticonus
namespace: Trait.ontology
def: "a conical bulging of the lens capsule and the underlying cortex of the eye" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001286 ! eye development
is_a: MT:0001303 ! lens morphology

[Term]
id: MT:0002796
name: skin barrier function
namespace: Trait.ontology
def: "impaired ability of the skin to regulate water loss; frequently leads to dehydration" [J:56641]
is_a: MT:0001784 ! fluid regulation
is_a: MT:0005501 ! skin physiology

[Term]
id: MT:0002800
name: short-term recognition memory
namespace: Trait.ontology
is_a: MT:0001458 ! object recognition memory
is_a: MT:0001468 ! temporal memory

[Term]
id: MT:0002801
name: long-term recognition memory
namespace: Trait.ontology
is_a: MT:0001458 ! object recognition memory
is_a: MT:0001468 ! temporal memory

[Term]
id: MT:0002802
name: discrimination learning
namespace: Trait.ontology
is_a: MT:0001449 ! learning/ memory

[Term]
id: MT:0002803
name: operant conditional behavior
namespace: Trait.ontology
is_a: MT:0002062 ! conditioning behavior

[Term]
id: MT:0002804
name: motor learning
namespace: Trait.ontology
is_a: MT:0001449 ! learning/ memory

[Term]
id: MT:0002806
name: conditioned emotional response
namespace: Trait.ontology
is_a: MT:0002062 ! conditioning behavior

[Term]
id: MT:0002807
name: eye blink conditioning behavior
namespace: Trait.ontology
is_a: MT:0002062 ! conditioning behavior

[Term]
id: MT:0002808
name: barbering
namespace: Trait.ontology
is_a: MT:0001440 ! grooming behavior

[Term]
id: MT:0002809
name: spinal cord size
namespace: Trait.ontology
def: "larger appearance of the spinal cord" [J:83935]
is_a: MT:0000955 ! spinal cord morphology

[Term]
id: MT:0002810
name: microcytic anemia
namespace: Trait.ontology
def: "anemia in which the circulating erythrocyte corpuscular volume is smaller than normal" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001577 ! anemia

[Term]
id: MT:0002811
name: macrocytic anemia
namespace: Trait.ontology
def: "anemia in which the circulating erythrocyte corpuscular volume is larger than normal" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001577 ! anemia

[Term]
id: MT:0002812
name: spherocytosis
namespace: Trait.ontology
def: "the presence of sphere-shaped erythrocytes in the circulating blood" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002447 ! erythrocyte morphology

[Term]
id: MT:0002813
name: microcytosis
namespace: Trait.ontology
def: "the presence of unusually small erythrocytes in the circulating blood" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "microcythemia" EXACT []
is_a: MT:0002447 ! erythrocyte morphology

[Term]
id: MT:0002814
name: hyperchromasia
namespace: Trait.ontology
def: "increased capacity of a cell to stain with dye; usually refers to staining of cell nuclei with hematoxylin" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "hyperchromatism" EXACT []
is_a: MT:0002447 ! erythrocyte morphology

[Term]
id: MT:0002815
name: adenoma
namespace: Trait.ontology
def: "a benign epithelial neoplasm with a glandular organization; usually does not invade or infiltrate surrounding tissue" [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0002816
name: colitis
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the colon region of the large intestine" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003304 ! large intestinal inflammation

[Term]
id: MT:0002817
name: tooth mineralization
namespace: Trait.ontology
def: "abnormalities in the process by which calcium salts are deposited into the dental enamel, dentin and cementum " [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "tooth mineralization defects" EXACT []
is_a: MT:0000116 ! tooth development
is_a: MT:0003930 ! tooth hard tissue morphology

[Term]
id: MT:0002818
name: dentin morphology
namespace: Trait.ontology
def: "defects in the hard portion of the tooth surrounding the pulp, covered by enamel on the crown and cementum on the root" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal dentin" EXACT []
synonym: "dentin abnormalities" EXACT []
synonym: "dentine abnormalities" EXACT []
is_a: MT:0003930 ! tooth hard tissue morphology

[Term]
id: MT:0002819
name: pulp cavity morphology
namespace: Trait.ontology
def: "defects in the central hollow space of a tooth" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal pulp cavity" EXACT []
synonym: "pulp cavity abnormalities" EXACT []
is_a: MT:0002100 ! tooth morphology

[Term]
id: MT:0002820
name: premaxilla morphology
namespace: Trait.ontology
def: "malformation or absence of the anterior and inner portion of the maxilla" [J:76662, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal incisive bone" EXACT []
synonym: "abnormal incisor bone" EXACT []
synonym: "abnormal intermaxillary bone" EXACT []
synonym: "abnormal premaxilla" EXACT []
is_a: MT:0000455 ! maxilla morphology

[Term]
id: MT:0002823
name: rib development
namespace: Trait.ontology
def: "anomalous formation of the bones forming the bony wall of the chest" [J:84754, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
is_a: MT:0000150 ! rib morphology
is_a: MT:0002113 ! skeleton development

[Term]
id: MT:0002824
name: chorioallantoic fusion
namespace: Trait.ontology
def: "abnormal process of or failure of the formation of the membrane that forms the fetal portion of the placenta; derived from the fusion of the chorion and the allantois" [hdene:Howard Dene_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001712 ! placental development
is_a: MT:0001726 ! allantois morphology
is_a: MT:0002836 ! chorion morphology

[Term]
id: MT:0002825
name: notochord morphology
namespace: Trait.ontology
def: "malformation or absence of the axial fibrocellular cord in embryos around which develops the vertebral primordia" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002085 ! embryonic tissue morphology

[Term]
id: MT:0002827
name: renal corpuscle morphology
namespace: Trait.ontology
def: "anomalous structure or development of either Bowman's capsules and/or the glomeruli contained therein" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
is_a: MT:0000521 ! kidney cortex
is_a: MT:0003881 ! nephron morphology

[Term]
id: MT:0002828
name: glomerular capsule morphology
namespace: Trait.ontology
def: "anomalous structure or development of the expanded beginning of a nephron that contains the glomerulus" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "abnormal Bowman's capsule" EXACT []
synonym: "abnormal capsula glomeruli" EXACT []
synonym: "abnormal malphighian capsule" EXACT []
is_a: MT:0002827 ! renal corpuscle morphology

[Term]
id: MT:0002829
name: juxtaglomerular apparatus morphology
namespace: Trait.ontology
def: "anomalous structure or development of the complex of modified smooth muscle cells consisting of juxtaglomerular cells, extraglomerular mesangium lacis cells, the macula densa of the distal convoluted tubule, and granular epithelial peripolar cells; these cells are found in the walls of afferent and efferent glomerular arterioles" [MeSH:National Library of Medicine_Medical Subject Headings, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
is_a: MT:0005325 ! glomerulus morphology

[Term]
id: MT:0002830
name: gallstones
namespace: Trait.ontology
def: "caliculi in the gallbladder or a bile duct; chemical composition of cholesterol, calcium carbonate or calcium bilirubinate" [il:Ira Lu_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "biliary caliculi" EXACT []
synonym: "cholelithiasis" EXACT []
synonym: "gall stone" EXACT []
is_a: MT:0005085 ! gall bladder physiology

[Term]
id: MT:0002831
name: Peyer's patch size
namespace: Trait.ontology
def: "area of lymphoid tissue of the mucosa of the small intestine" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "absence of Peyer's patches" EXACT []
is_a: MT:0000696 ! Peyer's patch morphology

[Term]
id: MT:0002832
name: coarse hair
namespace: Trait.ontology
def: "hair shafts that are twisted or coiled and are of uneven thickness produce an overall rugged or uneven appearance and roughness to the touch" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:56826, llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0002074 ! hair texture

[Term]
id: MT:0002835
name: cranial suture morphology
namespace: Trait.ontology
def: "defects of the fibrous joint in the bones of the head" [J:62161, MeSH:National Library of Medicine_Medical Subject Headings, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "abnormal cranial sutures" EXACT []
is_a: MT:0000438 ! skull morphology

[Term]
id: MT:0002836
name: chorion morphology
namespace: Trait.ontology
def: "malformations of the outermost extraembryonic membrane" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002086 ! extraembryonic tissue morphology

[Term]
id: MT:0002840
name: lens fiber morphology
namespace: Trait.ontology
def: "structural anomaly of the elongated cells of the crystalline lens of the eye" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005545 ! lens development

[Term]
id: MT:0002845
name: aorta weight
namespace: Trait.ontology
def: "mass of the main trunk of the systemic arteries times gravity" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "aortic weight" RELATED []
relationship: part_of MT:0007090 ! aorta size

[Term]
id: MT:0002846
name: aorta volume
namespace: Trait.ontology
def: "physical bulk of or total amount of space encompassed by the main trunk of the systemic arteries" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "aorta mass" RELATED []
synonym: "aortic volume" RELATED []
relationship: part_of MT:0007090 ! aorta size

[Term]
id: MT:0002847
name: glomerular filtration rate
namespace: Trait.ontology
def: "deviation from the normal volume of water filtered out of the plasma through glomerular capillary walls into the Bowman's capsule per unit time" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0003606 ! kidney function

[Term]
id: MT:0002849
name: saccharin consumption
namespace: Trait.ontology
is_a: MT:0001432 ! food preference

[Term]
id: MT:0002851
name: circulating sulfate level
namespace: Trait.ontology
def: "altered concentration of sulfate in the blood" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "abnormal sulfate level" EXACT []
is_a: MT:0000179 ! blood chemistry

[Term]
id: MT:0002855
name: cochlear ganglion morphology
namespace: Trait.ontology
def: "malformation, malfunction or absence of the group of nerve cell bodies that conveys auditory sensation from the organ of Corti to the hindbrain and resides on the cochlear part of the vestibulocochlear nerve (eighth cranial nerve)" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal auditory ganglion" EXACT []
synonym: "abnormal Corti ganglion" EXACT []
synonym: "abnormal spiral ganglion of vestibulocochlear (VIII) nerve" EXACT []
synonym: "cranial ganglion VIII" EXACT []
is_a: MT:0001081 ! cranial ganglia morphology

[Term]
id: MT:0002856
name: vestibular ganglion morphology
namespace: Trait.ontology
def: "malformation of the group of neurons associated with the vestibular part of the eighth cranial nerve that are involved in equilibration" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal Scarpa ganglion" EXACT []
synonym: "abnormal spiral ganglion" EXACT []
synonym: "abnormal vestibular ganglion of the vestibulocochlear (VIII) nerve" EXACT []
synonym: "cranial ganglion VIII" EXACT []
is_a: MT:0001081 ! cranial ganglia morphology

[Term]
id: MT:0002857
name: cochlear ganglion integrity
namespace: Trait.ontology
def: "loss of neural cell bodies in the group of nerve cell bodies that conveys auditory sensation from the organ of Corti to the hindbrain" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "degeneration of cochlear ganglion" EXACT []
synonym: "degeneration of spiral ganglion" EXACT []
is_a: MT:0002855 ! cochlear ganglion morphology

[Term]
id: MT:0002858
name: posterior semicircular canal
namespace: Trait.ontology
def: "form or structure of the posterior segment of the long bony tube of the labyrinth that is involved in the sense of balance" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002428 ! semicircular canal

[Term]
id: MT:0002860
name: dilated pupils
namespace: Trait.ontology
def: "pupils that remain widely opened regardless of light conditions" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001317 ! pupil morphology

[Term]
id: MT:0002861
name: tail bud morphology
namespace: Trait.ontology
def: "anomalous formation of the primordial region of the embryo that arises to form the tail of the adult; appears approximately ten days following conception as a short stump, and then initiates elongation and thinning in normal development" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0006281 ! tail development

[Term]
id: MT:0002862
name: righting response
namespace: Trait.ontology
is_a: MT:0001516 ! motor coordination/ balance

[Term]
id: MT:0002864
name: ocular fundus morphology
namespace: Trait.ontology
def: "malformation of the posterior concave interior of the eye, consisting of the retina, the choroid, the posterior segment of the sclera, the optic disk, and blood vessels, visible by an ophthalmoscope" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal fundus oculus" EXACT []
is_a: MT:0005195 ! posterior eye segment morphology

[Term]
id: MT:0002866
name: glutamic acid decarboxylase level
namespace: Trait.ontology
def: "aberrant concentration of this enzyme, which catalyzes the conversion of glutamate to gamma-aminobutyric acid (GABA) and carbon dioxide; determines GABA levels in nervous tissues" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
is_a: MT:0005319 ! enzyme/ coenzyme level

[Term]
id: MT:0002870
name: insulin autoantibody level
namespace: Trait.ontology
def: "reduced level of antibodies to insulin present in the sera" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0003726 ! autoantibody level

[Term]
id: MT:0002871
name: urine albumin level
namespace: Trait.ontology
def: "presence of excess albumin in the urine" [RGD:Rat Genome Database submission, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005160 ! urine protein level

[Term]
id: MT:0002872
name: polycythemia
namespace: Trait.ontology
def: "an excess of circulating red blood cells" [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001586 ! erythrocyte count

[Term]
id: MT:0002876
name: thyroid physiology
namespace: Trait.ontology
def: "anomalous function of this endocrine gland that normally produces hormones that regulate the metabolic rate of the body " [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal thyroid function" EXACT []
is_a: MT:0002164 ! gland physiology

[Term]
id: MT:0002877
name: melanocyte morphology
namespace: Trait.ontology
def: "malformation of the cells that produce pigment " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001186 ! pigmentation trait

[Term]
id: MT:0002878
name: corticospinal tract morphology
namespace: Trait.ontology
def: "anomaly in the structure of the fibers that arise from the cells within the cerebral cortex layer V, pass through the medullary pyramid, and descend into the gray matter of the spinal cord" [MeSH:National Library of Medicine_Medical Subject Headings, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "abnormal corticobulbar tract" EXACT []
synonym: "abnormal pyramidal tract" EXACT []
is_a: MT:0000778 ! tract morphology

[Term]
id: MT:0002879
name: cellular sensitivity to X-ray irradiation
namespace: Trait.ontology
def: "increased incidence of cell death following exposure to high levels of X-ray irradiation" [RGD:Rat Genome Database submission]
is_a: MT:0004228 ! cellular sensitivity to ionizing radiation

[Term]
id: MT:0002880
name: opisthotonus
namespace: Trait.ontology
def: "a form of tetanic spasm in which the head, neck and spine are bent backward and the body is bowed forward" [MeSH:National Library of Medicine_Medical Subject Headings]
comment: Stedman's says that both the -us and the -os spellings are correct and synonymous
synonym: "opisthotonos" EXACT []
is_a: MT:0000743 ! muscle spasms

[Term]
id: MT:0002882
name: neuron
namespace: Trait.ontology
def: "anomaly in the functional cells of the nervous system that receive, conduct, and transmit impulses " [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0003632 ! nervous system morphology

[Term]
id: MT:0002883
name: chromatolysis
namespace: Trait.ontology
def: "the dissolution of the granules of chromophil substance in a nerve cell body that may occur in injured cells or axons" [dlb:Donna Burkart_Mouse Genome Informatics Curator]
is_a: MT:0002882 ! neuron

[Term]
id: MT:0002884
name: branchial arches
namespace: Trait.ontology
def: "malformation or anomaly in the transient structures of the embryo that develop into regions of the head, neck and ears" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal pharyngeal arches" EXACT []
is_a: MT:0002085 ! embryonic tissue morphology
is_a: MT:0003935 ! craniofacial development

[Term]
id: MT:0002885
name: AMPA-mediated synaptic currents
namespace: Trait.ontology
def: "change in the measured amplitude or duration of response to stimulation of AMPA receptors" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002886 ! glutamate receptor currents

[Term]
id: MT:0002886
name: glutamate receptor currents
namespace: Trait.ontology
def: "change in the measured amplitude or duration of response to stimulation of glutamanergic receptors" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
is_a: MT:0002206 ! CNS synaptic transmission

[Term]
id: MT:0002888
name: NMDA-mediated synaptic currents
namespace: Trait.ontology
def: "change in the measured amplitude or duration of response to stimulation of NMDA receptors" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002886 ! glutamate receptor currents

[Term]
id: MT:0002889
name: hepatoma susceptibility
namespace: Trait.ontology
def: "likelihood of developing a malignant tumor composed of neoplastic liver cells" [RGD:Rat Genome Database submission]
is_a: MT:0002028 ! hepatoma

[Term]
id: MT:0002890
name: hepatoma resistance
namespace: Trait.ontology
def: "decreased likelihood of developing a malignant tumor composed of neoplastic liver cells" [RGD:Rat Genome Database submission]
is_a: MT:0002028 ! hepatoma

[Term]
id: MT:0002891
name: insulin sensitivity
namespace: Trait.ontology
def: "ability to clear glucose from the bloodstream when given insulin than normal; can result in hypoglycemia" [RGD:Rat Genome Database submission]
is_a: MT:0002078 ! glucose homeostasis

[Term]
id: MT:0002893
name: urine keto acid level
namespace: Trait.ontology
def: "excretion of urine having an elevated concentration of keto acids" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001757 ! urine chemistry

[Term]
id: MT:0002894
name: otolith morphology
namespace: Trait.ontology
def: "structure, form, or number of the crystalline particles composed of calcium carbonate and a protein which adhere to the gelatinous membrane of the maculae of the utricle and saccule (otolithic membrane)" [llw2:Linda Washburn_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "ear crystal morphology" EXACT []
synonym: "otoconia morphology" EXACT []
synonym: "statoconia morphology" EXACT []
synonym: "statolith morphology" EXACT []
is_a: MT:0002895 ! otolithic membrane morphology

[Term]
id: MT:0002895
name: otolithic membrane morphology
namespace: Trait.ontology
def: "form or structure of the gelatinous membrane which is supported by the stereocilia of the hair cells of the maculae of the saccule and utriculus of the inner ear;  adhering to its surface are numerous calciferous crystalline particles called otoliths (statoconia)" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "membrana statoconiorum morphology" EXACT []
synonym: "statoconial membrane morphology" EXACT []
is_a: MT:0004425 ! otolith organ morphology

[Term]
id: MT:0002896
name: bone mineralization
namespace: Trait.ontology
def: "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
subset: slim_chkn
is_a: MT:0001533 ! skeleton physiology

[Term]
id: MT:0002897
name: blotchy skin
namespace: Trait.ontology
def: "regions of spotted discoloration appearing in the dermal tissue" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001191 ! skin condition

[Term]
id: MT:0002899
name: stamina
namespace: Trait.ontology
synonym: "fatigability" EXACT []
synonym: "fatigable" EXACT []
is_a: MT:0002071 ! other behavior

[Term]
id: MT:0002900
name: urine phosphate level
namespace: Trait.ontology
def: "any change in the level of excretion of phosphate in the urine" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001757 ! urine chemistry

[Term]
id: MT:0002903
name: circulating parathyroid hormone level
namespace: Trait.ontology
def: "aberration in the blood concentration of this regulator of calcium and phosphorous concentration" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "abnormal circulating level of parathyroid hormone" EXACT []
synonym: "abnormal circulating PTH level" EXACT []
is_a: MT:0005418 ! circulating hormone level

[Term]
id: MT:0002907
name: parturition
namespace: Trait.ontology
def: "defect in the process of labor and delivery in female animals" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_pig
is_a: MT:0003699 ! female reproductive system physiology

[Term]
id: MT:0002908
name: time to wound healing
namespace: Trait.ontology
def: "longer time requirement for the ability to self-repair and close wounds than normal" [J:63037]
is_a: MT:0005023 ! wound healing

[Term]
id: MT:0002909
name: adrenal gland physiology
namespace: Trait.ontology
def: "altered ability of the surparenal gland to produce and secrete hormones " [hdene:Howard Dene_Mouse Genome Informatics Curator]
synonym: "abnormal adrenal gland function" EXACT []
is_a: MT:0002164 ! gland physiology

[Term]
id: MT:0002910
name: excitatory postsynaptic currents
namespace: Trait.ontology
def: "defect in the size or duration of currents detected in postsynaptic cells when an excitatory impulse arrives at the synapse causing depolarization" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal EPSCs" EXACT []
is_a: MT:0002206 ! CNS synaptic transmission

[Term]
id: MT:0002911
name: inhibitory postsynaptic potential
namespace: Trait.ontology
def: "defect in the membrane potential detected in postsynaptic cells when an inhibitory impulse arrives at the synapse causing hyperpolarization" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal IPSP" EXACT []
is_a: MT:0002206 ! CNS synaptic transmission

[Term]
id: MT:0002912
name: excitatory postsynaptic potential
namespace: Trait.ontology
def: "defect in the potential detected in postsynaptic cells when an excitatory impulse arrives at the synapse causing depolarization" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal EPSP" EXACT []
is_a: MT:0002206 ! CNS synaptic transmission

[Term]
id: MT:0002913
name: PNS synaptic transmission
namespace: Trait.ontology
def: "defect in the communication from a neuron to a target across a synapse in the peripheral nervous system" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0003635 ! synaptic transmission

[Term]
id: MT:0002914
name: endplate potential activity
namespace: Trait.ontology
def: "defect in the excitatory response of peripheral synapses to stimulation; these amplitudes are larger than central synapse potentials" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal end plate potential activity" EXACT []
synonym: "abnormal EPP activity" EXACT []
is_a: MT:0002913 ! PNS synaptic transmission

[Term]
id: MT:0002915
name: synaptic depression
namespace: Trait.ontology
def: "changes in the duration of the reduction of effectiveness of synaptic connections between neurons and target after repetitive stimulation" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
is_a: MT:0002206 ! CNS synaptic transmission

[Term]
id: MT:0002918
name: paired-pulse facilitation
namespace: Trait.ontology
def: "defects in the response of central synapses when activated twice in rapid succession; indicative of defects in short-term plasticity due to lack of increase of neurotransmitter release at the second stimulus" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal PPF" EXACT []
is_a: MT:0002206 ! CNS synaptic transmission

[Term]
id: MT:0002921
name: post-tetanic potential
namespace: Trait.ontology
def: "defects in the size or duration of potentials that persist after tetanic stimulation of central synapses" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal PTP" EXACT []
is_a: MT:0002206 ! CNS synaptic transmission

[Term]
id: MT:0002924
name: CNS synapse formation
namespace: Trait.ontology
def: "increase in time required to complete the process of generating connections between an axon and effector tissue or neuron " [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0000913 ! brain development

[Term]
id: MT:0002926
name: aganglionic megacolon
namespace: Trait.ontology
def: "extreme dilation of the colon due to defects in innervation from the ganglia, or absence of the ganglia of the myenteric plexus" [RGD:Rat Genome Database submission, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002731 ! megacolon

[Term]
id: MT:0002927
name: toxic megacolon
namespace: Trait.ontology
def: "severe non-obstructive dilation of the colon" [RGD:Rat Genome Database submission, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002731 ! megacolon

[Term]
id: MT:0002928
name: bile duct morphology
namespace: Trait.ontology
def: "malformation of the channels that secrete bile from the liver to the gall bladder and intestines" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
synonym: "abnormal bile duct" EXACT []
is_a: MT:0005083 ! biliary tract morphology

[Term]
id: MT:0002929
name: bile duct development
namespace: Trait.ontology
def: "incomplete or aberrant differentiation of the channels that secrete bile from the liver to the gall bladder and intestines" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
is_a: MT:0002928 ! bile duct morphology
is_a: MT:0003943 ! liver/biliary system development

[Term]
id: MT:0002931
name: glutaricadicuria
namespace: Trait.ontology
def: "an accumulation of an intermediate of tryptophan catabolism in the urine" [RGD:Rat Genome Database submission, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001757 ! urine chemistry

[Term]
id: MT:0002932
name: joint morphology
namespace: Trait.ontology
def: "defect in the articulation point of two or more bones" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
subset: slim_pig
is_a: MT:0005508 ! skeleton morphology

[Term]
id: MT:0002933
name: joint inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the joints" [RGD:Rat Genome Database submission]
is_a: MT:0001846 ! tissue specific inflammatory response
is_a: MT:0002932 ! joint morphology

[Term]
id: MT:0002934
name: acute joint inflammation
namespace: Trait.ontology
def: "early and often transient reaction of the microcirculation, characterized by movement of fluid and leukocytes from the blood into the joints; initiated by injury, infection, or local immune response " [RGD:Rat Genome Database submission]
is_a: MT:0002933 ! joint inflammation

[Term]
id: MT:0002935
name: chronic joint inflammation
namespace: Trait.ontology
def: "persistent inflammatory response in the joints, often caused by persistent infection or during an autoimmune response" [RGD:Rat Genome Database submission]
is_a: MT:0002933 ! joint inflammation

[Term]
id: MT:0002936
name: joint swelling
namespace: Trait.ontology
def: "enlargement of the joints, usually due to an accumulation of fluid" [RGD:Rat Genome Database submission]
subset: slim_pig
is_a: MT:0002932 ! joint morphology

[Term]
id: MT:0002937
name: synovial blood flow rate
namespace: Trait.ontology
def: "blood flow rate to the a synovial joint" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0001533 ! skeleton physiology
is_a: MT:0002128 ! blood circulation

[Term]
id: MT:0002938
name: white spotting
namespace: Trait.ontology
def: "the appearance of patches of white fur" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002075 ! coat color

[Term]
id: MT:0002939
name: head spot
namespace: Trait.ontology
def: "the appearance of a round area of white fur on the head" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002938 ! white spotting

[Term]
id: MT:0002940
name: variable body spotting
namespace: Trait.ontology
alt_id: MT:0000369
def: "the appearance of patches of white fur at random on the coat" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "white spotting" EXACT []
is_a: MT:0002938 ! white spotting

[Term]
id: MT:0002943
name: lactate dehydrogenase level
namespace: Trait.ontology
def: "aberrant concentration of this enzyme, which catalyzes the interconversion of lactate and pyruvate" [J:87714, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "abnormal LDH level" EXACT []
is_a: MT:0005319 ! enzyme/ coenzyme level

[Term]
id: MT:0002945
name: inhibitory postsynaptic currents
namespace: Trait.ontology
def: "defect in the size or duration of currents detected in postsynaptic cells when an inhibitory impulse arrives at the synapse causing hyperpolarization" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal IPSCs" EXACT []
is_a: MT:0002206 ! CNS synaptic transmission

[Term]
id: MT:0002946
name: time of axon outgrowth
namespace: Trait.ontology
def: "an increased amount of time required for an axon to extend from a neuron cell body and find the target" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:77048]
is_a: MT:0003651 ! axon outgrowth

[Term]
id: MT:0002947
name: hemangioma
namespace: Trait.ontology
def: "proliferation of blood vessels leading to a mass that resembles a neoplasm" [J:87544, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "angioma" EXACT []
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0002948
name: neuron specification
namespace: Trait.ontology
def: "defects in the developmental patterning of neurons resulting in ectopic placement, decreased numbers or absence of mature neurons" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:87948]
is_a: MT:0002882 ! neuron

[Term]
id: MT:0002949
name: neural crest cells morphology/development
namespace: Trait.ontology
def: "defect in the transient and migratory group of cells that emerge from the dorsal region of the neural tube and disperse to many peripheral locations to form various tissues of the adult" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
is_a: MT:0002151 ! neural tube morphology/development

[Term]
id: MT:0002950
name: neural crest cell migration
namespace: Trait.ontology
def: "defect in the dispersion of the transient and migratory group of cells that emerge from the dorsal region of the neural tube and migrate to many peripheral locations to form various tissues of the adult" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
is_a: MT:0002949 ! neural crest cells morphology/development

[Term]
id: MT:0002954
name: aerobic energy metabolism
namespace: Trait.ontology
alt_id: MT:0005622
def: "defect in respiratory chain energy production (oxidative metabolism) process in all living cells where oxygen is consumed and carbon dioxide and water are produced" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal cell respiration" EXACT []
synonym: "abnormal mitochondrial energy production" EXACT []
synonym: "abnormal respiratory chain function" EXACT []
is_a: MT:0006036 ! mitochondrial physiology

[Term]
id: MT:0002956
name: compensatory renal growth
namespace: Trait.ontology
def: "decreased additional growth of a kidney upon removal of the other kidney through surgery or disease" [RGD:Rat Genome Database submission]
is_a: MT:0002706 ! kidney size

[Term]
id: MT:0002957
name: intestinal adenocarcinoma
namespace: Trait.ontology
def: "malignant neoplasm of epithelial cells in the intestine" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
is_a: MT:0002038 ! carcinoma

[Term]
id: MT:0002958
name: aqueductal stenosis
namespace: Trait.ontology
def: "the most common form of obstructive hydrocephaly and results from narrowing of the aqueduct of Sylvius, which connects the third and fourth ventricles" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000917 ! obstructive hydrocephaly

[Term]
id: MT:0002960
name: microalbumin excretion
namespace: Trait.ontology
def: "less than the normal amount of fragments of this protein voided by the kidneys" [RGD:Rat Genome Database submission]
is_a: MT:0005555 ! kidney excretion

[Term]
id: MT:0002961
name: axon guidance
namespace: Trait.ontology
def: "defect in the signaling mechanisms that allow precise navigation and connections of axonal growth cones to effector tissues " [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
is_a: MT:0006008 ! neurogenesis

[Term]
id: MT:0002963
name: protein excretion
namespace: Trait.ontology
def: "less than the normal amount of serum proteins voided by the kidneys" [RGD:Rat Genome Database submission]
is_a: MT:0005555 ! kidney excretion

[Term]
id: MT:0002969
name: social transmission of food preference
namespace: Trait.ontology
is_a: MT:0002802 ! discrimination learning

[Term]
id: MT:0002970
name: white fat morphology
namespace: Trait.ontology
subset: slim_cattle
subset: slim_pig
is_a: MT:0000003 ! adipose tissue morphology

[Term]
id: MT:0002971
name: brown fat morphology
namespace: Trait.ontology
is_a: MT:0000003 ! adipose tissue morphology

[Term]
id: MT:0002972
name: cardiac muscle contractility
namespace: Trait.ontology
def: "ability of the heart muscle to shorten or to develop increased tension, often measured by dP/dT max" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
subset: slim_chkn
is_a: MT:0001544 ! cardiovascular system physiology
is_a: MT:0005620 ! muscle contractility

[Term]
id: MT:0002975
name: vascular smooth muscle size
namespace: Trait.ontology
def: "the physical dimensions, proportions, magnitude, or extent of the nonstriated, involuntary muscle tissue of the blood vessels" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0005592 ! blood vessel smooth muscle morphology

[Term]
id: MT:0002979
name: vestibular response
namespace: Trait.ontology
is_a: MT:0000353 ! vestibular system physiology
is_a: MT:0001525 ! balance

[Term]
id: MT:0002980
name: postural reflex
namespace: Trait.ontology
is_a: MT:0001961 ! reflex
is_a: MT:0003492 ! involuntary movement

[Term]
id: MT:0002982
name: germ cell migration
namespace: Trait.ontology
def: "defects in the orderly movement of a germ cell, a cell specialized to produce haploid gametes, from one site to another during development" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0001919 ! reproductive system physiology

[Term]
id: MT:0002983
name: retinal ganglion cell number
namespace: Trait.ontology
def: "greater number of cells in the innermost nuclear layer of the retina, which projects axons through the optic nerve to the brain" [il:Ira Lu_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0000965 ! sensory neuron morphology
is_a: MT:0005241 ! retinal ganglion layer morphology

[Term]
id: MT:0002985
name: urine calcium level
namespace: Trait.ontology
def: "any change in the level of excretion of calcium in the urine" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001757 ! urine chemistry

[Term]
id: MT:0002987
name: urine osmolarity
namespace: Trait.ontology
def: "changes in the concentration of ions in the urine compared to the normal state" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:83000]
is_a: MT:0001757 ! urine chemistry

[Term]
id: MT:0002990
name: ureter length
namespace: Trait.ontology
def: "reduced length of the tube that conducts the urine from the renal pelvis to the bladder" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003585 ! ureter size

[Term]
id: MT:0002991
name: sebaceous gland physiology
namespace: Trait.ontology
def: "anomalous function of any of the small, sacculated organs found within the dermis that normally secrete sebum" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "al sebaceous gland function" EXACT []
is_a: MT:0002164 ! gland physiology

[Term]
id: MT:0002992
name: sebaceous lipid secretion
namespace: Trait.ontology
def: "abnormal function of the sebaceous gland resulting in changes to the lipid profile secreted onto the hair and skin" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002991 ! sebaceous gland physiology

[Term]
id: MT:0002993
name: arthritis
namespace: Trait.ontology
def: "joint inflammation, marked by changes in the synovial membranes and thickening of articular structures, widespread degeneration of the collagen fibers in connective tissues, and by atrophy and rarefaction of bony structures" [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "rheumatoid arthritis" EXACT []
is_a: MT:0002933 ! joint inflammation

[Term]
id: MT:0002995
name: primary sex reversal
namespace: Trait.ontology
def: "gonad type is not consistent with chromosomal sex" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
synonym: "sex-reversed gonad" EXACT []
is_a: MT:0002211 ! primary sex determination
is_a: MT:0005652 ! sex reversal

[Term]
id: MT:0002996
name: ovotestis
namespace: Trait.ontology
def: "gonad with both ovarian and testicular tissue" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0002211 ! primary sex determination
is_a: MT:0003936 ! reproductive system development

[Term]
id: MT:0002997
name: seminal gland size
namespace: Trait.ontology
def: "increased size, compared to the normal state, of one of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0002059 ! seminal gland morphology

[Term]
id: MT:0002998
name: bone remodeling
namespace: Trait.ontology
def: "aberrant process of the turnover of bone matrix that involves a balance of resorption and formation by osteoclasts and osteoblasts, respectively" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0001533 ! skeleton physiology

[Term]
id: MT:0002999
name: bone healing
namespace: Trait.ontology
def: "defects in the restoration of integrity to bone after trauma" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002998 ! bone remodeling

[Term]
id: MT:0003000
name: susceptibility to lymphoma
namespace: Trait.ontology
def: "decreased likelihood of developing a neoplasm of any lymphoid tissue" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:87536, smb:Susan M. Bello]
is_a: MT:0005514 ! susceptibility to tumor development

[Term]
id: MT:0003005
name: hippocampal fimbria morphology
namespace: Trait.ontology
def: "malformations in the flattened band of efferent fibers arising from the subiculum and medial border of the hippocampus, which then thickens to form the fornix and fibers of the hippocampal commissure" [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000807 ! hippocampus morphology

[Term]
id: MT:0003006
name: hippocampal fornix morphology
namespace: Trait.ontology
def: "malformations in the compact, white, heavily myelinated fiber bundle arising from the Ammon horn of the hippocampus in each cerebral hemisphere and projecting to the hypothalamus and the mammillary body" [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000807 ! hippocampus morphology

[Term]
id: MT:0003007
name: ectopic thymus
namespace: Trait.ontology
def: "ectopic location of the thymus primordium, which normally resides in the superior mediastinum and lower part of the neck" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:76015]
is_a: MT:0000703 ! thymus morphology

[Term]
id: MT:0003009
name: cytokine secretion
namespace: Trait.ontology
def: "impairment or increase of the cellular release of any of the non-antibody proteins made by inflammatory leukocytes and some non-leukocytic cells that affect the behavior of other cells " [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005049 ! cytokine physiology

[Term]
id: MT:0003010
name: mortality induced by ionizing radiation
namespace: Trait.ontology
def: "reduced sensitivity to lethal doses of ionizing radiation such as ultraviolet light, X-rays, or gamma rays" [J:88888, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001657 ! induced morbidity/mortality

[Term]
id: MT:0003011
name: dark adaptation
namespace: Trait.ontology
def: "increase in time required for the eye to recover its sensitivity in the dark following exposure to bright lights" [hdene:Howard Dene_Mouse Genome Informatics Curator, J:68444]
is_a: MT:0005253 ! eye physiology

[Term]
id: MT:0003013
name: renal integrity
namespace: Trait.ontology
def: "wasting of the kidney due to injury or disease resulting in reduced size" [J:88636, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002136 ! kidney physiology

[Term]
id: MT:0003014
name: kidney medulla morphology
namespace: Trait.ontology
def: "anomalous structure of the inner portion of the kidney consisting of the renal pyramids" [J:88636, smb:Susan M. Bello_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal renal medulla" EXACT []
is_a: MT:0002135 ! kidney morphology

[Term]
id: MT:0003015
name: circulating bicarbonate level
namespace: Trait.ontology
def: "aberrant concentration of inorganic salts that contain the -HCO3 radical in the circulation, which are an important factor in regulating the pH of the blood " [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
is_a: MT:0000179 ! blood chemistry

[Term]
id: MT:0003018
name: circulating chloride level
namespace: Trait.ontology
def: "aberrant concentration of chlorine salts in the circulation" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
is_a: MT:0000179 ! blood chemistry

[Term]
id: MT:0003021
name: coronary flow rate
namespace: Trait.ontology
def: "rate of blood flow in the blood vessels supplying the heart" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0000233 ! blood flow velocity

[Term]
id: MT:0003024
name: coronary artery patency
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the openness of any of the blood vessels supplying the heart" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
relationship: part_of MT:0007053 ! coronary artery integrity

[Term]
id: MT:0003027
name: blood pH regulation
namespace: Trait.ontology
def: "anomaly in the function of the buffer systems of the blood in combination with the respiratory and renal systems that control the relative acidity or alkalinity of the blood, as measured by the concentration of the hydrogen ion" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, RGD:Rat Genome Database submission]
is_a: MT:0000179 ! blood chemistry
is_a: MT:0004043 ! pH regulation

[Term]
id: MT:0003028
name: alkalosis
namespace: Trait.ontology
def: "a pathological condition characterized by a decrease in the hydrogen ion concentration of arterial blood; caused by an increase in the concentration of alkaline compounds, or by a decrease in the concentration of acidic compounds or carbon dioxide to the body fluids" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003027 ! blood pH regulation

[Term]
id: MT:0003029
name: alkalemia
namespace: Trait.ontology
def: "decreased concentration of H-ion in the blood or a rise in pH" [RGD:Rat Genome Database submission, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003027 ! blood pH regulation

[Term]
id: MT:0003030
name: acidemia
namespace: Trait.ontology
def: "increased concentration of H-ion in the blood or a fall below normal in pH" [RGD:Rat Genome Database submission, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003027 ! blood pH regulation

[Term]
id: MT:0003031
name: acidosis
namespace: Trait.ontology
def: "a pathological state characterized by an increase in the hydrogen ion concentration of arterial blood; caused by an decrease in the concentration of alkaline compounds, or by a increase in the concentration of acidic compounds or carbon dioxide to the body fluids" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003027 ! blood pH regulation

[Term]
id: MT:0003033
name: pulmonary vascular resistance
namespace: Trait.ontology
def: "force opposing blood flow in the lung blood vessels" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0005532 ! vascular resistance

[Term]
id: MT:0003036
name: vertebral homeotic transformation
namespace: Trait.ontology
alt_id: MT:0000144
alt_id: MT:0000145
alt_id: MT:0000146
alt_id: MT:0000147
def: "homeotic transformation of a specific vertebrae to adopt the fate of another" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "transformation of C7 to T1" NARROW []
synonym: "transformation of L6 to S1" NARROW []
synonym: "transformation of T7 to T8" NARROW []
synonym: "transformation of TX to L1" NARROW []
synonym: "vertebral transformation" EXACT []
is_a: MT:0000137 ! vertebrae morphology

[Term]
id: MT:0003044
name: basement membrane formation
namespace: Trait.ontology
def: "defect in the development of the extracellular supportive tissue closely adjacent to the basal surface of the epithelium of muscle cells, fat cells and Schwann cells, which is comprised of type IV collagen, laminin, and sulfated proteoglycans and other components" [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "impaired basement lamina formation" EXACT []
is_a: MT:0004272 ! basement membrane morphology

[Term]
id: MT:0003045
name: fibrosis
namespace: Trait.ontology
def: "invasion of fibrous connective tissue into any organ or multiple organs, often resulting from inflammation or injury " [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0005395 ! other trait

[Term]
id: MT:0003046
name: liver cirrhosis
namespace: Trait.ontology
def: "liver disease in which the occurrence of fibrotic nodules cause diffuse damage to parenchymal cells, disruptions in microcirculation, vascular anatomy and hepatic architecture, resulting in hepatic dysfunction and ultimately, hepatic failure" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000598 ! liver morphology

[Term]
id: MT:0003047
name: thoracic vertebrae morphology
namespace: Trait.ontology
def: "malformation of any or all of the thirteen bony segments of the spine located anterior to the lumbar vertebrae and posterior to the cervical vertebrae" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_cattle
subset: slim_pig
is_a: MT:0000137 ! vertebrae morphology

[Term]
id: MT:0003048
name: cervical vertebrae morphology
namespace: Trait.ontology
def: "malformation of any or all of the seven bony segments of the spine located anterior to the thoracic vertebrae" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0000137 ! vertebrae morphology

[Term]
id: MT:0003049
name: lumbar vertebrae morphology
namespace: Trait.ontology
def: "malformation of any or all of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_cattle
subset: slim_pig
is_a: MT:0000137 ! vertebrae morphology

[Term]
id: MT:0003050
name: sacral vertebrae morphology
namespace: Trait.ontology
def: "malformation of any or all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0000137 ! vertebrae morphology

[Term]
id: MT:0003051
name: tail shape
namespace: Trait.ontology
def: "form of the tail" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002111 ! tail morphology

[Term]
id: MT:0003052
name: omphalocele
namespace: Trait.ontology
def: "protrusion of abdominal viscera at the base of the umbilical cord, with a covering membranous sac of peritoneum-amnion" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "amniocele" EXACT []
synonym: "exomphalos" EXACT []
synonym: "exumbilication" EXACT []
synonym: "umbilical hernia" EXACT []
is_a: MT:0001725 ! umbilical cord morphology
is_a: MT:0003257 ! abdominal wall morphology

[Term]
id: MT:0003054
name: spina bifida
namespace: Trait.ontology
def: "common congenital midline defect of fusion of the vertebral arch" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0000929 ! open neural tube

[Term]
id: MT:0003055
name: epiphyseal plate morphology
namespace: Trait.ontology
def: "malformed or absent cartilaginous center of ossification on the long bones permitting growth of the bone in both directions during development" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal growth plate morphology" EXACT []
is_a: MT:0000163 ! cartilage morphology
is_a: MT:0002113 ! skeleton development

[Term]
id: MT:0003056
name: hyoid bone morphology
namespace: Trait.ontology
def: "anomalous structure of the U-shaped bone lying between the mandible and the larynx that supports the tongue muscles" [hdene:Howard Dene_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal lingual bone" EXACT []
is_a: MT:0002116 ! craniofacial bone morphology

[Term]
id: MT:0003057
name: epicardium morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the visceral layer of the pericardium that surrounds and attaches to all the surfaces of the heart" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "lamina visceralis pericardii morphology" EXACT []
synonym: "morphology of the visceral layer of serous pericardium" EXACT []
xref: MP:0003057
relationship: part_of MT:0000288 ! pericardium morphology

[Term]
id: MT:0003061
name: aerobic running capacity
namespace: Trait.ontology
def: "reduced ability to run at defined speeds and/or distances compared to controls" [RGD:Rat Genome Database submission]
is_a: MT:0000348 ! aerobic fitness

[Term]
id: MT:0003065
name: hepatic copper content
namespace: Trait.ontology
def: "anomalous level of copper present in the liver tissue" [RGD:Rat Genome Database submission]
synonym: "abnormal liver copper concentration" EXACT []
is_a: MT:0000609 ! liver physiology
is_a: MT:0003952 ! copper level

[Term]
id: MT:0003069
name: superior semicircular canal
namespace: Trait.ontology
def: "form or structure of the upper, superior segment of the long bony tube of the labyrinth that is involved in the sense of balance" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "anterior semicircular canal morphology" EXACT []
is_a: MT:0002428 ! semicircular canal

[Term]
id: MT:0003072
name: metatarsal bone morphology
namespace: Trait.ontology
def: "anomaly in the five bones of the hindpaws that articulate proximally with the cuneiform and cuboid bones of the tarsus and distally with the phalanges" [Anatomy of the Rat:Greene EC_Hafner Publishing Co_1935, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
subset: slim_pig
is_a: MT:0002115 ! skeleton extremities morphology

[Term]
id: MT:0003073
name: metacarpal bone morphology
namespace: Trait.ontology
def: "anomaly in the five bones of the forepaws that articulate proximally with the carpal bones and distally with the phalanges" [Anatomy of the Rat:Greene EC_Hafner Publishing Co_1935, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_pig
is_a: MT:0002115 ! skeleton extremities morphology

[Term]
id: MT:0003074
name: metacarpal bone number
namespace: Trait.ontology
def: "number of bones of the forepaws/hands that articulate proximally with the carpal bones and distally with the phalanges" [Anatomy of the Rat:Greene EC_Hafner Publishing Co_1935, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003073 ! metacarpal bone morphology

[Term]
id: MT:0003075
name: response to CNS ischemic injury
namespace: Trait.ontology
def: "abnormal response to loss of circulation in a region of the brain; may be induced or spontaneous" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "response to stroke" EXACT []
is_a: MT:0006080 ! CNS ischemia

[Term]
id: MT:0003077
name: cell cycle
namespace: Trait.ontology
def: "failure to progress or abnormal progression through the stages of the cell cycle" [J:91266, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005621 ! cell physiology

[Term]
id: MT:0003078
name: aphakia
namespace: Trait.ontology
def: "absence of the crystalline lens of the eye" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "absence of lens" EXACT []
synonym: "absent lens" EXACT []
is_a: MT:0001303 ! lens morphology

[Term]
id: MT:0003079
name: susceptibility to induced joint inflammation
namespace: Trait.ontology
def: "reduced or absent inflammatory response in the joints due to chemical or mechanical agents" [RGD:Rat Genome Database submission]
is_a: MT:0002933 ! joint inflammation

[Term]
id: MT:0003080
name: NK cell cytolysis
namespace: Trait.ontology
def: "ability of these cells to destroy or dissolve targeted cells" [RGD:Rat Genome Database submission]
is_a: MT:0005069 ! NK cell physiology

[Term]
id: MT:0003081
name: soleus morphology
namespace: Trait.ontology
def: "anomaly in the superficial flat broad muscle of the calf that is responsible for plantar flexion of the foot" [smb:Susan M. Bello_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003358 ! hypaxial muscle morphology

[Term]
id: MT:0003082
name: gastrocnemius morphology
namespace: Trait.ontology
def: "anomaly in the two-headed large muscle of the posterior portion of the lower hindleg, the most superficial of the calf muscles" [smb:Susan M. Bello_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003358 ! hypaxial muscle morphology

[Term]
id: MT:0003083
name: tibialis anterior morphology
namespace: Trait.ontology
def: "anomaly in the muscle of the shin that is responsible for dorsiflexion and inversion of the foot" [smb:Susan M. Bello_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003358 ! hypaxial muscle morphology

[Term]
id: MT:0003084
name: skeletal muscle fiber morphology
namespace: Trait.ontology
def: "anomalous structure of the skeletal muscle fibers, the large multinucleated cells that make up the skeletal muscles" [smb:Susan M. Bello_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_pig
is_a: MT:0000759 ! skeletal muscle morphology
is_a: MT:0004087 ! muscle fiber morphology

[Term]
id: MT:0003085
name: egg cylinder morphology
namespace: Trait.ontology
def: "anomaly in the transient cup-like structure of the epiblast that consists of a single layer of embryonic cells" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002085 ! embryonic tissue morphology

[Term]
id: MT:0003086
name: hydromyelia
namespace: Trait.ontology
def: "increased fluid in the central canal of the spinal cord" [J:57948, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "hydrorrhachis" EXACT []
is_a: MT:0000254 ! cerebrospinal fluid volume
is_a: MT:0000955 ! spinal cord morphology

[Term]
id: MT:0003088
name: prepulse inhibition
namespace: Trait.ontology
def: "increase or decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [J:91131, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002206 ! CNS synaptic transmission

[Term]
id: MT:0003090
name: muscle progenitor cell migration
namespace: Trait.ontology
def: "defects in the movement of cells that will develop into muscle cells out of the somites and/or to the appropriate location in the body" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal myogenic progenitor cell migration" EXACT []
is_a: MT:0000729 ! myogenesis

[Term]
id: MT:0003091
name: cell migration
namespace: Trait.ontology
def: "defect in the movement of cells during developmental processes" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005384 ! cellular trait

[Term]
id: MT:0003092
name: corneal stroma thickness
namespace: Trait.ontology
def: "reduced width of the lamellated connective tissue layer of the cornea" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:81616]
is_a: MT:0005300 ! corneal stroma morphology
is_a: MT:0005543 ! corneal thickness

[Term]
id: MT:0003093
name: anterior stroma morphology
namespace: Trait.ontology
def: "structural anomaly of the anterior segment of the lamellated connective tissue layer of the cornea" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:81616, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0005300 ! corneal stroma morphology

[Term]
id: MT:0003094
name: posterior stroma morphology
namespace: Trait.ontology
def: "structural anomaly of the posterior segment of the lamellated connective tissue layer of the cornea" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:81616, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0005300 ! corneal stroma morphology

[Term]
id: MT:0003095
name: corneal stroma development
namespace: Trait.ontology
def: "anomalous differentiation of the lamellated connective tissue layer of the cornea" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:81616]
is_a: MT:0001286 ! eye development
is_a: MT:0005300 ! corneal stroma morphology

[Term]
id: MT:0003096
name: corneal light-scattering
namespace: Trait.ontology
def: "anomaly in the normal transmission of light through the cornea; light is reflected or absorbed instead; often due to anomalies in the arrangement of lamella in the corneal stroma" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, J:81616]
is_a: MT:0005253 ! eye physiology

[Term]
id: MT:0003097
name: tendon stiffness
namespace: Trait.ontology
def: "altered ability of tendon to maintain tensile strength and load" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0002106 ! muscle physiology

[Term]
id: MT:0003099
name: retinal detachment
namespace: Trait.ontology
def: "detachment of the retina from the underlying inner wall of the eye, often from tension of the vitreous; may occur with aging or as a result of trauma" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:83544]
synonym: "detached retina" EXACT []
synonym: "retinal tear" EXACT []
is_a: MT:0001325 ! retina morphology

[Term]
id: MT:0003100
name: myopia
namespace: Trait.ontology
def: "optical condition in which only rays from a finite distance from the eye focus on the retina" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:83544]
synonym: "near sight" EXACT []
synonym: "nearsightedness" EXACT []
synonym: "short sight" EXACT []
synonym: "shortsightedness" EXACT []
is_a: MT:0002090 ! vision

[Term]
id: MT:0003101
name: high myopia
namespace: Trait.ontology
def: "an optical condition involving enlarging of the eye, scleral thinning and frequent detachment of the retina resulting from stress associated with excessive axial elongation" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:83544]
is_a: MT:0003100 ! myopia

[Term]
id: MT:0003102
name: sclera thickness
namespace: Trait.ontology
def: "reduction in the width of the fibrous, outer envelope of the eyeball, the sclera may appear blue as a result of the underlying epithelium showing through" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:83544]
synonym: "blue sclera" EXACT []
is_a: MT:0002698 ! sclera morphology

[Term]
id: MT:0003103
name: liver integrity
namespace: Trait.ontology
def: "deterioration of the liver due to injury or disease, often accompanied by loss of function" [J:91653, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000609 ! liver physiology

[Term]
id: MT:0003104
name: skull size
namespace: Trait.ontology
def: "volume or area of the skull" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:33716]
synonym: "absent skull" EXACT []
is_a: MT:0000438 ! skull morphology

[Term]
id: MT:0003105
name: heart atrium morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the upper chamber(s) of the heart that recieve blood from the vasculature and send blood into a ventricle" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "cardiac atrial morphology" RELATED []
synonym: "cardiac atrium morphology" RELATED []
relationship: part_of MT:0000266 ! cardiac morphology

[Term]
id: MT:0003107
name: response to novelty
namespace: Trait.ontology
subset: slim_chkn
subset: slim_pig
is_a: MT:0002572 ! emotion/affect behavior

[Term]
id: MT:0003110
name: malleal processus brevis morphology
namespace: Trait.ontology
def: "form or structure of the part of the malleus that contacts the upper part of the tympanic membrane where the tympanic cavity makes a deep pocket (epitympanic pocket) surrounding this cartilaginous nodule" [PMID:12701100]
is_a: MT:0000029 ! malleus morphology

[Term]
id: MT:0003111
name: nucleus morphology
namespace: Trait.ontology
def: "abnormalities in the nucleus and/or its surrounding membrane" [J:91473, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000358 ! cell content/ morphology

[Term]
id: MT:0003112
name: parathyroid gland size
namespace: Trait.ontology
def: "increased size of the two small, paired endocrine glands, usually found embedded in the connective tissue capsule on the posterior surface of the thyroid gland; they secrete parathyroid hormone (PTH) that regulates calcium and phosphorous metabolism" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000678 ! parathyroid gland morphology

[Term]
id: MT:0003114
name: pigmented parathyroid gland
namespace: Trait.ontology
def: "presence of melanocytes and/or melanin in either of the two small, paired endocrine glands, usually found embedded in the connective tissue capsule on the posterior surface of the thyroid gland; they secrete parathyroid hormone (PTH) that regulates calcium and phosphorous metabolism" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000678 ! parathyroid gland morphology

[Term]
id: MT:0003115
name: respiratory system development
namespace: Trait.ontology
def: "aberrant differentiation of pulmonary tissues" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002132 ! respiratory system morphology

[Term]
id: MT:0003116
name: rickets
namespace: Trait.ontology
def: "overproduction and deficient calcification of osteoid tissue due to vitamin D deficiency; can lead to skeletal deformities, growth defects, hypocalcemia, and sometimes tetany; skeletal fractures occur frequently" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002896 ! bone mineralization

[Term]
id: MT:0003117
name: tracheal-esophageal septation
namespace: Trait.ontology
def: "partial or complete failure of the trachea and esophagus to separate during development" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003115 ! respiratory system development
is_a: MT:0003119 ! digestive system development

[Term]
id: MT:0003118
name: tracheal-bronchial branching morphogenesis
namespace: Trait.ontology
def: "partial or complete failure of the trachea and bronchi to repeatedly divide during development of the lung" [J:91723, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003115 ! respiratory system development
is_a: MT:0003119 ! digestive system development

[Term]
id: MT:0003119
name: digestive system development
namespace: Trait.ontology
def: "dysmorphology of the organ system that converts ingested food to nutrients and energy" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000462 ! digestive system morphology

[Term]
id: MT:0003120
name: tracheal cartilage morphology
namespace: Trait.ontology
def: "any structural anomaly of the cartilaginous structures that support the trachea" [J:97123, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002282 ! trachea morphology

[Term]
id: MT:0003121
name: genomic imprinting
namespace: Trait.ontology
def: "phenotype resulting from inactivation of specific loci during gametogenesis, but not encoded by the DNA itself" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0005395 ! other trait

[Term]
id: MT:0003122
name: maternal imprinting
namespace: Trait.ontology
def: "specific loci are inactivated during oogenesis and are not expressed in offspring" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0003121 ! genomic imprinting

[Term]
id: MT:0003123
name: paternal imprinting
namespace: Trait.ontology
def: "specific loci are inactivated during spermatogenesis and are not expressed in offspring " [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0003121 ! genomic imprinting

[Term]
id: MT:0003124
name: hypospadia
namespace: Trait.ontology
def: "a urethral opening located below the normal location; in males, the opening is usually on the ventral surface of the penis, and in females, the opening is usually in the vagina" [J:91491, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "hypospadis" EXACT []
is_a: MT:0000537 ! urethra morphology

[Term]
id: MT:0003125
name: septation of the cloaca
namespace: Trait.ontology
def: "absence of or reduction in the separation of the single opening of the digestive, urinary, and reproductive tracts (cloaca) into multiple isolated openings during development, may result in hypospadia, reduced anogenital distance, or persistent cloaca" [J:91491, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003119 ! digestive system development
is_a: MT:0003936 ! reproductive system development
is_a: MT:0003942 ! urinary system development

[Term]
id: MT:0003126
name: vulva morphology
namespace: Trait.ontology
def: "anomaly in the structure of the external genitalia of the female" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001119 ! female reproductive anatomy

[Term]
id: MT:0003127
name: clitoris morphology
namespace: Trait.ontology
def: "anomaly in the structure of the small, erectile body located at the anterior end of the vulva" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003126 ! vulva morphology

[Term]
id: MT:0003128
name: splayed clitoris
namespace: Trait.ontology
def: "flattened or spread out clitoris" [J:91491, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003127 ! clitoris morphology

[Term]
id: MT:0003129
name: persistent cloaca
namespace: Trait.ontology
def: "the presence of a single external opening to which the urinary, digestive and reproductive tracts all connect" [J:91491, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000516 ! urinary system morphology
is_a: MT:0003125 ! septation of the cloaca
is_a: MT:0003936 ! reproductive system development

[Term]
id: MT:0003130
name: anal atresia
namespace: Trait.ontology
def: "absence of a connection between the anal pit and the rectum" [J:91491, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000492 ! rectum morphology
is_a: MT:0005034 ! anus morphology

[Term]
id: MT:0003132
name: pre-B cell number
namespace: Trait.ontology
def: "greater number of progenitor cells that form the B cell component of the immune system" [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7, J:91592, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002403 ! pre-B cell morphology/development

[Term]
id: MT:0003133
name: early pro-B cell number
namespace: Trait.ontology
def: "greater number of cells in the B lymphocyte lineage that undergo D-J rearrangement of the immunoglobulin heavy chain" [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7, J:91592, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005019 ! early pro-B cell morphology/development

[Term]
id: MT:0003134
name: late pro-B cell number
namespace: Trait.ontology
def: "greater number of the cells in the B lymphocyte lineage that undergo V-DJ rearrangement of the immunoglobulin heavy chain" [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7, J:91592, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005020 ! late pro-B cell morphology/development

[Term]
id: MT:0003135
name: erythrocyte precursor number
namespace: Trait.ontology
def: "greater numbers of progenitors of the erythrocyte lineage" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002424 ! reticulocyte morphology/development

[Term]
id: MT:0003136
name: yellow coat color
namespace: Trait.ontology
def: "amount and distribution of yellow pigment (phaeomelanin) relative to black or brown pigment (eumelanin) is increased compared to wild-type agouti" [llw2:Linda L. Washburn_Mouse Genome Informatics Curator]
is_a: MT:0002075 ! coat color

[Term]
id: MT:0003137
name: impulse conducting system function
namespace: Trait.ontology
def: "function of the impulse-conducting system composed of modified cardiac muscle and having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0001544 ! cardiovascular system physiology

[Term]
id: MT:0003140
name: atrium size
namespace: Trait.ontology
def: "the physical dimensions, proportions, magnitude, or extent of the upper chamber(s) of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "atrial size" RELATED []
relationship: part_of MT:0003105 ! heart atrium morphology
relationship: part_of MT:0005406 ! heart size

[Term]
id: MT:0003141
name: heart tissue composition
namespace: Trait.ontology
def: "any measurable or observable characteristic pertaining to the types and ratios of cells within the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "cardiac tissue composition" RELATED []
relationship: part_of MT:0000266 ! cardiac morphology

[Term]
id: MT:0003143
name: otolith size
namespace: Trait.ontology
def: "average diameter or volume of the crystalline calciferous particles adhering to the otolithic membrane" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:67072]
synonym: "ear crystal size" EXACT []
synonym: "otoconia size" EXACT []
synonym: "statoconia size" EXACT []
synonym: "statolith size" EXACT []
is_a: MT:0002894 ! otolith morphology

[Term]
id: MT:0003144
name: otolith number
namespace: Trait.ontology
def: "average number of the crystalline calciferous particles adhering to the otolithic membrane" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:30611]
synonym: "decreased number of otoliths" EXACT []
synonym: "reduced number of otoconia" EXACT []
is_a: MT:0002894 ! otolith morphology

[Term]
id: MT:0003145
name: otolithic membrane integrity
namespace: Trait.ontology
def: "susceptibility of the otolithic (otoconial) membrane to detach from the underlying neuroepithelium" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:60193]
is_a: MT:0002895 ! otolithic membrane morphology

[Term]
id: MT:0003148
name: cochlear coiling
namespace: Trait.ontology
def: "number of turns in the cochlea; in wild-type mice, the cochlea most commonly exhibits one and three-fourth turns" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:56294]
is_a: MT:0000031 ! cochlea morphology

[Term]
id: MT:0003149
name: tectorial membrane morphology
namespace: Trait.ontology
def: "form or structure of the overlaying membrane of cochlear duct, an extracellular matrix of the inner ear that contacts the stereocilia bundles of specialized sensory hair cells; sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia, and leads to fluctuations in hair cell membrane potential, transducing sound into electrical signals" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:77634]
is_a: MT:0003169 ! scala media morphology

[Term]
id: MT:0003150
name: tectorial membrane integrity
namespace: Trait.ontology
def: "tendency of the tectorial membrane to detach from the cochlear epithelium or spiral limbus" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:77634]
is_a: MT:0003149 ! tectorial membrane morphology

[Term]
id: MT:0003151
name: tunnel of Corti morphology
namespace: Trait.ontology
def: "form or structure of the triangular, fluid-filled space normally found between the inner and outer rows of supporting pillar cells in the organ of Corti" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:32991]
is_a: MT:0000042 ! organ of Corti

[Term]
id: MT:0003152
name: pillar cell differentiation
namespace: Trait.ontology
def: "process by which cells attain the specialized charateristics of the supporting cells that form the inner and outer walls of the tunnel in the organ of Corti" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:32991]
is_a: MT:0004300 ! organ of Corti supporting cell morphology

[Term]
id: MT:0003154
name: soft palate
namespace: Trait.ontology
def: "abnormality in the musculomembranous fold that partly separates the mouth and pharynx, located behind the hard palate" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal velum" EXACT []
synonym: "abnormal velum palatinum" EXACT []
is_a: MT:0003755 ! palate

[Term]
id: MT:0003155
name: telomere length
namespace: Trait.ontology
def: "abnormal length of the terminal section of a chromosome which has a specialized structure and which is involved in chromosomal replication and stability; normal length is a few hundred base pairs" [hdene:Howard Dene_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0003702 ! chromosome morphology

[Term]
id: MT:0003156
name: lymphocyte migration/homing
namespace: Trait.ontology
def: "altered ability of blood lymphocytes to bind to high endothelial venules (HEV), tether and roll along the luminal aspects of HEV, and migrate into the lymph nodes" [acv:Alicia Valenzuela_Genetic Resources Curator, J:92231]
is_a: MT:0002442 ! leukocyte physiology

[Term]
id: MT:0003158
name: ease of swallowing
namespace: Trait.ontology
def: "difficulty in swallowing food or liquid" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "impaired swallowing" EXACT []
is_a: MT:0001663 ! digestive system physiology

[Term]
id: MT:0003159
name: esophageal smooth muscle morphology
namespace: Trait.ontology
def: "structural anomaly of the nonstriated, involuntary muscle tissue lining the esophagus" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000767 ! smooth muscle morphology

[Term]
id: MT:0003160
name: esophageal development
namespace: Trait.ontology
def: "aberrant formation of the part of the digestive canal through which food passes from the pharynx to the stomach" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000467 ! esophagus morphology
is_a: MT:0003119 ! digestive system development

[Term]
id: MT:0003162
name: lateral semicircular canal size
namespace: Trait.ontology
def: "area or volume of the lateral long bony tube of the labyrinth that is involved in the sense of balance " [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000037 ! lateral semicircular canal

[Term]
id: MT:0003164
name: posterior semicircular canal size
namespace: Trait.ontology
def: "area or volume of the posterior segment of the long bony tube of the labyrinth that is involved in the sense of balance" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002858 ! posterior semicircular canal

[Term]
id: MT:0003166
name: superior semicircular canal size
namespace: Trait.ontology
def: "area or volume of the upper, superior segment of the long bony tube of the labyrinth that is involved in the sense of balance" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "anterior semicircular canal size" EXACT []
is_a: MT:0003069 ! superior semicircular canal

[Term]
id: MT:0003167
name: scala tympani morphology
namespace: Trait.ontology
def: "form of structure of the division of the spiral canal of the cochlea lying on the basal side of the spiral lamina" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:56294]
is_a: MT:0000031 ! cochlea morphology

[Term]
id: MT:0003168
name: scala vestibuli morphology
namespace: Trait.ontology
def: "form or structure of the division of the spiral canal of the cochlea lying on the apical side of the spiral lamina and vestibular membrane" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "perilymphatic space morphology" EXACT []
synonym: "vestibular canal morphology" EXACT []
synonym: "vestibular chamber morphology" EXACT []
is_a: MT:0000031 ! cochlea morphology

[Term]
id: MT:0003169
name: scala media morphology
namespace: Trait.ontology
def: "form or structure of the division of the spiral canal of the cochlea that contains the organ of Corti (the neuroepithelial receptor organ for hearing)" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:23837, J:46972]
synonym: "cochlear chamber morphology" EXACT []
synonym: "cochlear duct morphology" EXACT []
synonym: "Lowenberg scala morphology" EXACT []
is_a: MT:0000031 ! cochlea morphology

[Term]
id: MT:0003170
name: susceptibility to stomach tumor
namespace: Trait.ontology
def: "reduced likelihood of developing an abnormal growth of gastric tissue" [RGD:Rat Genome Database submission]
synonym: "resistance to gastric tumor" EXACT []
is_a: MT:0005514 ! susceptibility to tumor development

[Term]
id: MT:0003172
name: lysosome physiology
namespace: Trait.ontology
def: "ability of lysosomes to produce enzymes necessary for digestion of exogenous material is impaired" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0005621 ! cell physiology

[Term]
id: MT:0003173
name: lysosomal enzyme secretion
namespace: Trait.ontology
def: "production of glycoprotein hydrolytic enzymes is decreased compared to normal" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
synonym: "reduced lysosomal enzyme secretion" EXACT []
is_a: MT:0003172 ! lysosome physiology

[Term]
id: MT:0003178
name: left pulmonary isomerism
namespace: Trait.ontology
def: "bilaterally symmetric left lung pattern (or altered asymmetric patterning of the lung)" [J:93051, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000542 ! left-sided isomerism
is_a: MT:0001175 ! lung morphology

[Term]
id: MT:0003179
name: platelet count
namespace: Trait.ontology
alt_id: MT:0002749
def: "fewer than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, hdene:Howard Dene_Mouse Genome Informatics Curator, J:93052]
synonym: "reduced platelet count" EXACT []
synonym: "thrombocytopenia" EXACT []
synonym: "thrombopenia" EXACT []
is_a: MT:0000228 ! thrombopoiesis

[Term]
id: MT:0003180
name: pulmonary endothelial cell surface area
namespace: Trait.ontology
def: "area of the semipermeable membrane that encloses the cytoplasm of a pulmonary endothelial cell" [ms:mary shimoyama]
relationship: part_of MT:0000484 ! pulmonary artery morphology
relationship: part_of MT:0004007 ! lung blood vessel morphology
relationship: part_of MT:0006055 ! blood vessel endothelial cell morphology

[Term]
id: MT:0003183
name: peptide metabolism
namespace: Trait.ontology
def: "anomaly in the biochemical modification and homeostasis of molecules consisting of linked amino acids and their derivatives" [RGD:Rat Genome Database submission]
is_a: MT:0005621 ! cell physiology

[Term]
id: MT:0003185
name: angiotensin I-converting enzyme activity
namespace: Trait.ontology
def: "reduced activity of the exopeptidase that catalyses the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, and is also involved in the inactivation of bradykinin" [RGD:Rat Genome Database submission]
synonym: "decreased ACE activity" EXACT []
is_a: MT:0003183 ! peptide metabolism

[Term]
id: MT:0003186
name: redox activity
namespace: Trait.ontology
def: "defect in the processes that maintain the redox environment of a cell or compartment within a cell " [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0005621 ! cell physiology

[Term]
id: MT:0003189
name: fused joints
namespace: Trait.ontology
def: "partial or complete absence of the articulation point of two or more bones" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002932 ! joint morphology

[Term]
id: MT:0003190
name: fused synovial joints
namespace: Trait.ontology
def: "partial or complete absence of separations containing synovial fluid between bones" [J:93028, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003189 ! fused joints

[Term]
id: MT:0003191
name: cellular cholesterol metabolism
namespace: Trait.ontology
def: "impaired regulation of cellular cholesterol levels" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0005621 ! cell physiology

[Term]
id: MT:0003193
name: cholesterol efflux
namespace: Trait.ontology
def: "reduced level of removal of excess cholesterol from cells by an active transport pathway" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, RGD:Rat Genome Database submission]
is_a: MT:0003191 ! cellular cholesterol metabolism

[Term]
id: MT:0003194
name: frequency of paradoxical sleep
namespace: Trait.ontology
synonym: "abnormal frequency of REM sleep" EXACT []
is_a: MT:0001501 ! sleep pattern

[Term]
id: MT:0003195
name: calcinosis
namespace: Trait.ontology
def: "pathologic deposition of calcium salts in tissues " [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
is_a: MT:0005395 ! other trait

[Term]
id: MT:0003196
name: skin calcification
namespace: Trait.ontology
def: "pathologic deposition of calcium salts in the skin" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
is_a: MT:0005501 ! skin physiology

[Term]
id: MT:0003197
name: kidney calcification
namespace: Trait.ontology
def: "pathologic deposition of calcium salts in the kidney" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
is_a: MT:0002136 ! kidney physiology

[Term]
id: MT:0003198
name: tendon calcification
namespace: Trait.ontology
def: "pathologic deposition of calcium salts in the tendons" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
is_a: MT:0001533 ! skeleton physiology

[Term]
id: MT:0003199
name: muscle calcification
namespace: Trait.ontology
def: "pathologic deposition of calcium salts in muscle" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
is_a: MT:0002106 ! muscle physiology

[Term]
id: MT:0003200
name: joint calcification
namespace: Trait.ontology
def: "pathologic deposition of calcium salts in the joints" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
is_a: MT:0001533 ! skeleton physiology

[Term]
id: MT:0003201
name: extremity edema
namespace: Trait.ontology
def: "an accumulation of serous fluid in the limbs, paws and tail" [RGD:Rat Genome Database submission]
is_a: MT:0001785 ! edema

[Term]
id: MT:0003202
name: neuron apoptosis
namespace: Trait.ontology
def: "change in the timing or the number of neurons undergoing programmed cell death" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002882 ! neuron

[Term]
id: MT:0003207
name: cellular sensitivity to gamma-irradiation
namespace: Trait.ontology
def: "decreased incidence of cell death following exposure to high levels of gamma-irradiation" [J:92917, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0004228 ! cellular sensitivity to ionizing radiation

[Term]
id: MT:0003208
name: neuromere morphology
namespace: Trait.ontology
def: "malformation of the segments of the developing neural tube" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002151 ! neural tube morphology/development

[Term]
id: MT:0003209
name: pulmonary elastic fiber morphology
namespace: Trait.ontology
def: "malformation of a slender connective tissue fiber in pulmonary tissue characterized by great elasticity" [RGD:Rat Genome Database submission, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001175 ! lung morphology

[Term]
id: MT:0003210
name: heart elastic fiber morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the slender connective tissue fiber in cardiac tissue characterized by great elasticity" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "cardiac elastic fiber morphology" RELATED []
xref: MP:0003210
relationship: part_of MT:0000266 ! cardiac morphology

[Term]
id: MT:0003211
name: aorta elastic tissue morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the slender connective tissue fiber in aortic tissue characterized by great elasticity" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "aortic elastic fiber morphology" RELATED []
relationship: part_of MT:0000272 ! aorta morphology
relationship: part_of MT:0006083 ! blood vessel elastic tissue morphology

[Term]
id: MT:0003212
name: susceptibility to age related obesity
namespace: Trait.ontology
def: "probability of excessive weight gain that is progressive with age" [RGD:Rat Genome Database submission]
is_a: MT:0005456 ! weight gain

[Term]
id: MT:0003214
name: neurofibrillary tangles
namespace: Trait.ontology
def: "dense intraneuronal accumulations of helical filaments (neurofilaments and microtubules) that assume twisted contorted patterns; found in subclasses of cells of the neocortex, hippocampus, brain stem, and diencephalon in individuals with Alzheimer disease and other tauopathies" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002152 ! brain morphology

[Term]
id: MT:0003215
name: renal interstitial fibrosis
namespace: Trait.ontology
def: "formation of fibrous tissue within the interstices of the kidney as a result of repair or a reactive process" [RGD:Rat Genome Database submission]
is_a: MT:0003985 ! renal fibrosis

[Term]
id: MT:0003224
name: neuron integrity
namespace: Trait.ontology
def: "a retrogressive impairment of function or destruction of the functional cells of the nervous system that receive, conduct, and transmit impulses " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002229 ! neural integrity

[Term]
id: MT:0003225
name: axonal dystrophy
namespace: Trait.ontology
def: "axon degeneration resulting from inadequate or faulty metabolism" [RGD:Rat Genome Database submission]
is_a: MT:0005405 ! axon integrity

[Term]
id: MT:0003228
name: sinus venosus morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the cavity at the caudal end of the embryonic cardiac tube in which the veins from the intra- and extraembryonic circulatory arcs unite; in the adult this becomes the portion of the right atrium known as the sinus of the vena cava" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0000267 ! heart development

[Term]
id: MT:0003229
name: vitelline vascular morphology
namespace: Trait.ontology
def: "malformation in the vessels of the yolk sac" [J:93257, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal yolk sac vasculature" EXACT []
is_a: MT:0001718 ! yolk sac morphology

[Term]
id: MT:0003231
name: placental vascular morphology
namespace: Trait.ontology
def: "malformation in the vessels of the placenta" [J:93157, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001711 ! placenta morphology

[Term]
id: MT:0003232
name: forebrain development
namespace: Trait.ontology
def: "anomaly in the formation or patterning of the anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [J:93081, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000783 ! forebrain morphology
is_a: MT:0000913 ! brain development

[Term]
id: MT:0003235
name: alisphenoid bone morphology
namespace: Trait.ontology
def: "malformation in either of the broad curved wing like expanses on each side of the sphenoid bone in adults; may exist independently in the young" [J:93183, smb:Susan M. Bello_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000104 ! sphenoid bone morphology

[Term]
id: MT:0003236
name: lens capsule morphology
namespace: Trait.ontology
def: "malformation in the elastic, clear, membrane-like structure, that is outer most layer of the lens" [J:93301, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001303 ! lens morphology

[Term]
id: MT:0003237
name: lens epithelium morphology
namespace: Trait.ontology
def: "malformation in the one or more of the layers of epithelial cells in the lens" [J:93301, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001303 ! lens morphology

[Term]
id: MT:0003239
name: REM rate
namespace: Trait.ontology
synonym: "fast rapid eye movement" EXACT []
is_a: MT:0001501 ! sleep pattern

[Term]
id: MT:0003240
name: hippocampal neuron number
namespace: Trait.ontology
def: "loss of neurons in the hippocampal region of the brain, commonly due to an apoptotic event" [RGD:Rat Genome Database submission]
comment: note Charles W. considered this a distinct term from degeneration
is_a: MT:0000807 ! hippocampus morphology

[Term]
id: MT:0003241
name: cerebral cortex neuron number
namespace: Trait.ontology
def: "loss of neurons in the cortex region of the brain, commonly due to an apoptotic event" [RGD:Rat Genome Database submission]
comment: Note that charles w. considers this distinct from degeneration
is_a: MT:0000788 ! cerebral cortex morphology

[Term]
id: MT:0003242
name: basal ganglia neuron number
namespace: Trait.ontology
def: "loss of neurons in the basal ganglia of the brain, commonly due to an apoptotic event" [RGD:Rat Genome Database submission]
comment: Note that Charles W. considers this distinct from degeneration
is_a: MT:0006007 ! basal ganglion morphology

[Term]
id: MT:0003243
name: dopaminergic neuron morphology
namespace: Trait.ontology
def: "malformation or absence of the neurons that utilize dopamine as a neurotransmitter " [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
is_a: MT:0002882 ! neuron

[Term]
id: MT:0003244
name: dopaminergic neuron number
namespace: Trait.ontology
def: "loss of the neurons that utilize dopamine as a neurotransmitter, commonly due to an apoptotic event" [RGD:Rat Genome Database submission]
is_a: MT:0003243 ! dopaminergic neuron morphology

[Term]
id: MT:0003245
name: GABA neuron morphology
namespace: Trait.ontology
def: "malformation or absence of the neurons that utilize gamma-aminobutyric acid as a neurotransmitter " [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal GABA neurons" EXACT []
is_a: MT:0002882 ! neuron

[Term]
id: MT:0003246
name: GABA neuron number
namespace: Trait.ontology
def: "loss of the neurons that utilize gamma-aminobutyric acid as a neurotransmitter, commonly due to an apoptotic event" [RGD:Rat Genome Database submission]
is_a: MT:0003245 ! GABA neuron morphology

[Term]
id: MT:0003247
name: glutaminergic neuron
namespace: Trait.ontology
def: "malformation or absence of the neurons that utilize glutamate as a neurotransmitter " [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
is_a: MT:0002882 ! neuron

[Term]
id: MT:0003248
name: glutamate neuron number
namespace: Trait.ontology
def: "loss of the neurons that utilize glutamate as a neurotransmitter, commonly due to an apoptotic event" [RGD:Rat Genome Database submission]
is_a: MT:0003247 ! glutaminergic neuron

[Term]
id: MT:0003249
name: muscle free fatty acid level
namespace: Trait.ontology
def: "higher than normal muscle level of organic, monobasic acids derived from hydrocarbons; they are saturated and unsaturated" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
synonym: "elevated muscle free fatty acid (FFA)" EXACT []
is_a: MT:0002106 ! muscle physiology

[Term]
id: MT:0003251
name: gall bladder inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the gall bladder" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001846 ! tissue specific inflammatory response
is_a: MT:0005085 ! gall bladder physiology

[Term]
id: MT:0003252
name: bile duct physiology
namespace: Trait.ontology
def: "anomalous action or function of the channels that secrete bile from the liver to the gall bladder and intestines" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002139 ! liver/biliary system physiology

[Term]
id: MT:0003253
name: bile duct size
namespace: Trait.ontology
def: "abnormal distention of the bile ducts due to accumulation of fluid or bile" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003252 ! bile duct physiology

[Term]
id: MT:0003254
name: bile duct inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the bile ducts" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "cholangitis" EXACT []
is_a: MT:0001846 ! tissue specific inflammatory response
is_a: MT:0003252 ! bile duct physiology

[Term]
id: MT:0003255
name: bile duct proliferation
namespace: Trait.ontology
def: "the appearance of an increased number of bile ducts in the liver; a sign of progressive liver disease" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003252 ! bile duct physiology

[Term]
id: MT:0003256
name: biliary cirrhosis
namespace: Trait.ontology
def: "liver damage to parenchymal cells due to obstruction of bile flow in the bile ducts" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003252 ! bile duct physiology

[Term]
id: MT:0003257
name: abdominal wall morphology
namespace: Trait.ontology
def: "malformation in the margins that enclose the abdominal cavity; the major part is muscular but also includes skin, subcutaneous fat, fascia and the parietal peritoneum" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003385 ! body wall morphology

[Term]
id: MT:0003258
name: hiatal hernia
namespace: Trait.ontology
def: "protrusion of abdominal structures through the esophageal hiatus of the diaphragm" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003257 ! abdominal wall morphology

[Term]
id: MT:0003259
name: nausea
namespace: Trait.ontology
def: "gastric discomfort associated with the inclination to vomit" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001664 ! digestion

[Term]
id: MT:0003260
name: vomiting
namespace: Trait.ontology
def: "the retrograde expulsion of gastric contents through the oral cavity" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001664 ! digestion

[Term]
id: MT:0003261
name: hematemesis
namespace: Trait.ontology
def: "vomiting of blood; indicative of bleeding in the upper gastrointestinal tract" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
synonym: "vomiting blood" EXACT []
is_a: MT:0003260 ! vomiting

[Term]
id: MT:0003262
name: intestinal/bowel diverticulum
namespace: Trait.ontology
def: "a pouch or sac protruding from the intestinal or bowel wall " [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000477 ! intestine morphology

[Term]
id: MT:0003263
name: cholesterol biosynthesis
namespace: Trait.ontology
def: "altered ability to form cholesterol from constituent compounds" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003191 ! cellular cholesterol metabolism

[Term]
id: MT:0003266
name: biliary cysts
namespace: Trait.ontology
def: "the appearance of fluid-filled sacs within the bile ducts" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
synonym: "choledochal cyst" EXACT []
synonym: "choledochocele" EXACT []
synonym: "common bile duct cyst" EXACT []
is_a: MT:0002928 ! bile duct morphology

[Term]
id: MT:0003267
name: constipation
namespace: Trait.ontology
def: "incomplete, infrequent or difficult evacuation of fecal matter " [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003866 ! defecation

[Term]
id: MT:0003268
name: chronic constipation
namespace: Trait.ontology
def: "prolonged or long-term difficulty in evacuation of fecal matter " [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003267 ! constipation

[Term]
id: MT:0003269
name: colonic polyps
namespace: Trait.ontology
def: "abnormal tissue masses that protrude into the lumen of the colon and are tethered to the wall of the colon" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000495 ! colon morphology

[Term]
id: MT:0003270
name: intestinal obstruction
namespace: Trait.ontology
def: "any impediment, blockage, or reversal of the normal flow of the intestinal contents toward the anus " [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001664 ! digestion

[Term]
id: MT:0003271
name: duodenum morphology
namespace: Trait.ontology
def: "malformation in the first division of the small intestine that extends from the pyloris to the junction with the jejunum " [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0000496 ! small intestine morphology

[Term]
id: MT:0003272
name: duodenal atresia
namespace: Trait.ontology
def: "congenital blockage or absence of the lumen of the duodenum" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003271 ! duodenum morphology

[Term]
id: MT:0003273
name: duodenal ulcer
namespace: Trait.ontology
def: "a lesion on the mucosal surface of the duodenum, usually produced by the sloughing of inflammatory necrotic tissue" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
synonym: "Curling ulcer" EXACT []
is_a: MT:0003271 ! duodenum morphology
is_a: MT:0003301 ! peptic ulcer

[Term]
id: MT:0003274
name: intestinal microaneurysm
namespace: Trait.ontology
def: "focal dilation of arteriocapillary junctions in the intestine" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000477 ! intestine morphology

[Term]
id: MT:0003275
name: gastric microaneurysm
namespace: Trait.ontology
def: "focal dilation of arteriocapillary junctions in the stomach" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000470 ! stomach morphology

[Term]
id: MT:0003276
name: esophageal atresia
namespace: Trait.ontology
def: "congenital blockage or absence of the lumen of the esophagus" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
synonym: "esophageal narrowing" EXACT []
is_a: MT:0000467 ! esophagus morphology

[Term]
id: MT:0003277
name: esophageal papilloma
namespace: Trait.ontology
def: "benign epithelial tumor of the esophagus" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0002014 ! papilloma

[Term]
id: MT:0003278
name: esophageal inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins and leukocytes in the esophagus" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
synonym: "esophagitis" EXACT []
synonym: "inflammation of esophagus" EXACT []
is_a: MT:0001663 ! digestive system physiology
is_a: MT:0001846 ! tissue specific inflammatory response

[Term]
id: MT:0003280
name: urinary incontinence
namespace: Trait.ontology
def: "inability to control the urinary excretory functions" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001756 ! urination

[Term]
id: MT:0003281
name: fecal incontinence
namespace: Trait.ontology
def: "inability to control the anal sphincter resulting in the involuntary passage of feces" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003866 ! defecation

[Term]
id: MT:0003282
name: gastric ulcer
namespace: Trait.ontology
def: "a lesion on the mucosal surface of the stomach, usually produced by the sloughing of inflammatory necrotic tissue" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000470 ! stomach morphology
is_a: MT:0003301 ! peptic ulcer

[Term]
id: MT:0003283
name: digestive organ placement
namespace: Trait.ontology
def: "different location or arrangement of any of the alimentary tract organs" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000462 ! digestive system morphology

[Term]
id: MT:0003284
name: large intestine placement
namespace: Trait.ontology
def: "different location or arrangement of the large intestinal tract" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000489 ! large intestine morphology
is_a: MT:0003283 ! digestive organ placement

[Term]
id: MT:0003286
name: gastroesophageal reflux
namespace: Trait.ontology
def: "retrograde movement of gastric or duodenal contents into the esophagus" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001664 ! digestion

[Term]
id: MT:0003287
name: intestinal hemangioma
namespace: Trait.ontology
def: "a benign tumor of the intestine, originating from the overgrowth of blood vessels" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
synonym: "intestinal angioma" EXACT []
is_a: MT:0002947 ! hemangioma

[Term]
id: MT:0003288
name: intestinal edema
namespace: Trait.ontology
def: "an accumulation of an excessive amount of serous fluid in the intestine or intestinal cells " [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001663 ! digestive system physiology
is_a: MT:0001785 ! edema

[Term]
id: MT:0003289
name: intestinal peristalsis
namespace: Trait.ontology
def: "altered intestinal movement characterized by waves of alternate circular contraction and relaxation of the muscular walls of the bowel that move bowel contents forward" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001664 ! digestion

[Term]
id: MT:0003292
name: melena
namespace: Trait.ontology
def: "dark colored, foul-smelling feces due to the presence of blood" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "blood in feces" EXACT []
synonym: "melanorhhagia" EXACT []
synonym: "melanorrhea" EXACT []
is_a: MT:0003868 ! feces composition

[Term]
id: MT:0003293
name: rectal hemorrhage
namespace: Trait.ontology
def: "bleeding in the rectum" [ncbi:Matthew Mailman_NCBI request]
synonym: "rectal bleeding" EXACT []
is_a: MT:0000465 ! gastrointestinal hemorrhage

[Term]
id: MT:0003294
name: intussusception
namespace: Trait.ontology
def: "telescoping of the intestine, or the prolapse of one part of the bowel to another; usually results in obstruction" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000477 ! intestine morphology

[Term]
id: MT:0003295
name: lymphomesenteric cysts
namespace: Trait.ontology
def: "cystic mass in the abdominal mesenchyme containing lymph; sometimes becomes calcified" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000462 ! digestive system morphology

[Term]
id: MT:0003296
name: microcolon
namespace: Trait.ontology
def: "small, unused colon in neonates, usually due to atresia or other gastrointestinal blockage" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000495 ! colon morphology

[Term]
id: MT:0003297
name: fibromatosis
namespace: Trait.ontology
def: "widespread or multiple benign tumors of fibrous or fully developed connective tissue " [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
synonym: "fibroma" EXACT []
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0003298
name: choking
namespace: Trait.ontology
def: "spasm of the larynx and trachea due to prevention of respiration by compression or obstruction" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002133 ! respiratory system physiology

[Term]
id: MT:0003299
name: gastric polyps
namespace: Trait.ontology
def: "abnormal tissue masses that protrude into the lumen of the stomach and are tethered to the wall of the colon" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000470 ! stomach morphology

[Term]
id: MT:0003300
name: gastrointestinal ulcer
namespace: Trait.ontology
def: "any lesion on the mucosal surface of the gastrointestinal tract, usually produced by the sloughing of inflammatory necrotic tissue" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000462 ! digestive system morphology

[Term]
id: MT:0003301
name: peptic ulcer
namespace: Trait.ontology
def: "any lesion on the mucosal surface of the portion of the alimentary tract that is exposed to gastric acid, usually in the stomach or the duodenum" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "gastroduodenal ulcer" EXACT []
synonym: "marginal ulcer" EXACT []
is_a: MT:0003300 ! gastrointestinal ulcer

[Term]
id: MT:0003302
name: perirectal abscess
namespace: Trait.ontology
def: "acute focal inflammation of the tissues surrounding the rectum, often with accumulation of purulent material" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000492 ! rectum morphology

[Term]
id: MT:0003303
name: peritoneal inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the membrane that lines the abdominal cavity and covers most of the viscera" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "peritoneum inflammation" EXACT []
is_a: MT:0001663 ! digestive system physiology
is_a: MT:0001846 ! tissue specific inflammatory response

[Term]
id: MT:0003304
name: large intestinal inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the large intestine" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001858 ! intestinal inflammation

[Term]
id: MT:0003305
name: proctitis
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the mucous membrane of the rectum" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003304 ! large intestinal inflammation

[Term]
id: MT:0003306
name: small intestinal inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the small intestine" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001858 ! intestinal inflammation

[Term]
id: MT:0003307
name: pyloric stenosis
namespace: Trait.ontology
def: "a narrowing of the gastric outlet of the stomach, often due to muscular hypertrophy or scarring from local inflammation" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000470 ! stomach morphology

[Term]
id: MT:0003308
name: cochlear sensory epithelium morphology
namespace: Trait.ontology
def: "structure of the epithelial cell layer containing the sensory hair cells and their associated sensory nerve terminals" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "cochlear neuroepithelium morphology" EXACT []
synonym: "inner ear neuroepithelium morphology" EXACT []
is_a: MT:0000031 ! cochlea morphology

[Term]
id: MT:0003309
name: modiolus morphology
namespace: Trait.ontology
def: "form or internal structure of the central conical bony pillar of the cochlea" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:66787]
is_a: MT:0000031 ! cochlea morphology

[Term]
id: MT:0003310
name: modiolus size
namespace: Trait.ontology
def: "length, width, volume, or area of the central conical bony pillar of the cochlea" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:66787]
is_a: MT:0003309 ! modiolus morphology

[Term]
id: MT:0003311
name: urine amino acid level
namespace: Trait.ontology
def: "excretion of amino acids in the urine, especially in excessive amounts" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:66560]
synonym: "hyperaminoaciduria" EXACT []
is_a: MT:0001757 ! urine chemistry

[Term]
id: MT:0003312
name: locomotor coordination
namespace: Trait.ontology
is_a: MT:0001392 ! locomotor activity

[Term]
id: MT:0003313
name: locomotor activation
namespace: Trait.ontology
subset: slim_pig
is_a: MT:0001392 ! locomotor activity

[Term]
id: MT:0003314
name: control of range of motion
namespace: Trait.ontology
is_a: MT:0001516 ! motor coordination/ balance

[Term]
id: MT:0003315
name: perineum morphology
namespace: Trait.ontology
def: "malformation in the area between the genital organs and the anus that lies beneath the pelvic diaphragm" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000462 ! digestive system morphology
is_a: MT:0002160 ! reproductive system morphology

[Term]
id: MT:0003316
name: perineal fistula
namespace: Trait.ontology
def: "an abnormal anatomical passage that connects the perineum to organs such as the bladder or the rectum " [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003315 ! perineum morphology

[Term]
id: MT:0003317
name: anoperineal fistula
namespace: Trait.ontology
def: "an abnormal anatomical passage that connects the perineum to the anus" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003316 ! perineal fistula
is_a: MT:0005034 ! anus morphology

[Term]
id: MT:0003318
name: rectoperineal fistula
namespace: Trait.ontology
def: "an abnormal anatomical passage that connects the perineum to the rectum " [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
synonym: "rectoperitoneal fistula" EXACT []
is_a: MT:0000492 ! rectum morphology
is_a: MT:0003316 ! perineal fistula

[Term]
id: MT:0003319
name: anal fistula
namespace: Trait.ontology
def: "an abnormal anatomical passage at or near the anus that usually opens into the rectum above the internal sphincter" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005034 ! anus morphology

[Term]
id: MT:0003320
name: rectovaginal fistula
namespace: Trait.ontology
def: "an abnormal anatomical passage connecting the rectum and the vagina " [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000492 ! rectum morphology
is_a: MT:0001139 ! vagina morphology

[Term]
id: MT:0003321
name: tracheoesophageal fistula
namespace: Trait.ontology
def: "an abnormal passage between the esophagus and the trachea, acquired or congenital, often associated with esophageal atresia" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
synonym: "esophagotracheal fistula" EXACT []
is_a: MT:0000467 ! esophagus morphology
is_a: MT:0002282 ! trachea morphology

[Term]
id: MT:0003322
name: biliary fistula
namespace: Trait.ontology
def: "an abnormal anatomical passage that connects any organ of the biliary tract and other organs " [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0005083 ! biliary tract morphology

[Term]
id: MT:0003323
name: gastrocolic fistula
namespace: Trait.ontology
def: "an abnormal anatomical passage between the stomach and the colon" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000470 ! stomach morphology
is_a: MT:0000495 ! colon morphology

[Term]
id: MT:0003324
name: liver adenoma
namespace: Trait.ontology
def: "benign epithelial neoplasm of the liver" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002815 ! adenoma

[Term]
id: MT:0003325
name: liver function
namespace: Trait.ontology
def: "reduced normal function of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000609 ! liver physiology

[Term]
id: MT:0003326
name: liver failure
namespace: Trait.ontology
def: "cessation of function of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000609 ! liver physiology

[Term]
id: MT:0003327
name: liver cysts
namespace: Trait.ontology
def: "abnormal membranous sacs in any portion of the liver" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000598 ! liver morphology

[Term]
id: MT:0003328
name: portal blood pressure
namespace: Trait.ontology
def: "elevation of arterial blood pressure in the hepatic portal system, often a result of cirrhosis or of blockage of the portal vein" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000609 ! liver physiology

[Term]
id: MT:0003329
name: amyloid beta deposits
namespace: Trait.ontology
def: "formation of self-assembled aggregates of the App Abeta protein fragment; often seen in neurodegenerative disorders such as Alzheimer's disease" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "amyloid beta plaques" EXACT []
is_a: MT:0003632 ! nervous system morphology

[Term]
id: MT:0003330
name: auditory tube morphology
namespace: Trait.ontology
def: "form or structure of the tube connecting the tympanic cavity and the nasopharynx that allows equalization of pressure between the tympanic cavity and the environment" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "Eustachian tube morphology" EXACT []
synonym: "pharyngotympanic tube morphology" EXACT []
is_a: MT:0000049 ! middle ear morphology

[Term]
id: MT:0003331
name: hepatocellular carcinoma
namespace: Trait.ontology
alt_id: MT:0005510
def: "malignant neoplasm arising from liver cells" [ncbi:Matthew Mailman_NCBI request]
synonym: "liver neoplasia" EXACT []
synonym: "liver neoplasm" EXACT []
synonym: "neoplastic liver" EXACT []
is_a: MT:0002019 ! tumor incidence
is_a: MT:0002038 ! carcinoma

[Term]
id: MT:0003332
name: liver abscess
namespace: Trait.ontology
def: "collection of purulent exudate within the liver as a result of infection by bacteria, protozoa, or other agents " [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000598 ! liver morphology

[Term]
id: MT:0003333
name: liver fibrosis
namespace: Trait.ontology
def: "invasion of fibrous connective tissue into the liver, often resulting from inflammation or injury " [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
synonym: "hepatic fibrosis" EXACT []
is_a: MT:0000598 ! liver morphology

[Term]
id: MT:0003334
name: pancreatic fibrosis
namespace: Trait.ontology
def: "invasion of fibrous connective tissue into the pancreas, often resulting from inflammation or injury " [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001944 ! pancreas morphology

[Term]
id: MT:0003336
name: pancreatic cysts
namespace: Trait.ontology
def: "the appearance of fluid-filled sacs within the pancreas" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001944 ! pancreas morphology

[Term]
id: MT:0003338
name: pancreatic lipomatosis
namespace: Trait.ontology
def: "an accumulation of abnormally localized or tumor-like fat in the pancreas" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001944 ! pancreas morphology

[Term]
id: MT:0003339
name: number of pancreatic beta cells
namespace: Trait.ontology
def: "fewer than normal number of the cells of the pancreas that secrete insulin" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0005217 ! pancreatic beta cell morphology

[Term]
id: MT:0003340
name: acute pancreas inflammation
namespace: Trait.ontology
def: "early and often transient reaction of the microcirculation, characterized by movement of fluid and leukocytes from the blood into the pancreas; initiated by injury, infection, or local immune response " [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001869 ! pancreas inflammation

[Term]
id: MT:0003341
name: chronic pancreas inflammation
namespace: Trait.ontology
def: "persistent inflammatory response in the pancreas, often caused by persistent infection or during an autoimmune response" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001869 ! pancreas inflammation

[Term]
id: MT:0003342
name: accessory spleen
namespace: Trait.ontology
def: "the splenic tissue is divided into equal masses; often related to situs inversus" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "polysplenia" EXACT []
is_a: MT:0000689 ! spleen morphology

[Term]
id: MT:0003343
name: fibroadenoma
namespace: Trait.ontology
def: "a benign epithelial neoplasm containing fibrous tissue" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0002815 ! adenoma

[Term]
id: MT:0003345
name: number of ribs
namespace: Trait.ontology
def: "fewer than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000150 ! rib morphology

[Term]
id: MT:0003346
name: pectoral muscle morphology
namespace: Trait.ontology
def: "anomaly in the two muscles that make up the upper and fore part of the chest that adduct and rotate the arm and lift the ribs" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
is_a: MT:0000759 ! skeletal muscle morphology

[Term]
id: MT:0003349
name: circulating renin level
namespace: Trait.ontology
def: "aberrant blood concentration of this enzyme which is secreted by the kidney; it cleaves a bond in angiotensionogen to generate angiotensin I " [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000179 ! blood chemistry
is_a: MT:0005319 ! enzyme/ coenzyme level

[Term]
id: MT:0003351
name: circulating levels of thyroid hormone
namespace: Trait.ontology
def: "reduced concentration of hormones in the blood that are synthesized and secreted by the thyroid" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0005418 ! circulating hormone level
is_a: MT:0005468 ! thyroid hormone level

[Term]
id: MT:0003354
name: astrocytosis
namespace: Trait.ontology
def: "a proliferation or spread of astrocytes in the area of a degenerative lesion or damaged tissue" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002183 ! gliosis

[Term]
id: MT:0003356
name: luteinization
namespace: Trait.ontology
def: "atypical transformation of the mature ovarian follicle and its theca interna into a corpus luteum after ovulation" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:43075, J:57854]
subset: slim_pig
is_a: MT:0001126 ! ovary morphology

[Term]
id: MT:0003357
name: granulosa cell differentiation
namespace: Trait.ontology
def: "atypical differentiation of the layer of small cells that forms the wall of an ovarian follicle" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:43075]
is_a: MT:0001131 ! ovarian follicle morphology

[Term]
id: MT:0003358
name: hypaxial muscle morphology
namespace: Trait.ontology
def: "malformation of the muscles derived from the lateral myotome and lateral portion of the dermomyotome; these include the thoracic intercostal and abdominal muscles, limb muscles and superficial back muscles, as well as the diaphragm and the tip of the tongue" [PMID:1591996]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "abnormal limb muscle morphology" EXACT []
is_a: MT:0000759 ! skeletal muscle morphology

[Term]
id: MT:0003359
name: hypaxial muscle cell number
namespace: Trait.ontology
def: "reduced cell number in the thoracic intercostal and abdominal muscles, limb muscles and superficial back muscles, as well as the diaphragm and the tip of the tongue" [PMID:1591996]
is_a: MT:0003358 ! hypaxial muscle morphology

[Term]
id: MT:0003361
name: circulating gonadotropin level
namespace: Trait.ontology
def: "aberrant blood concentration of the peptide hormones that stimulate gonadal functions such as gametogenesis and sex steroid hormone production in the ovary and the testis" [MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0005418 ! circulating hormone level

[Term]
id: MT:0003364
name: insulinoma
namespace: Trait.ontology
def: "a pancreatic islet beta cell adenoma that secretes excess insulin" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "beta-cell adenoma" EXACT []
synonym: "beta-cell tumor" EXACT []
synonym: "insuloma" EXACT []
is_a: MT:0003430 ! islet cell adenoma

[Term]
id: MT:0003365
name: glucagonoma
namespace: Trait.ontology
def: "a pancreatic islet alpha cell adenoma that secretes excess glucagon" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
synonym: "alpha-cell adenoma" EXACT []
synonym: "alpha-cell tumor" EXACT []
is_a: MT:0003430 ! islet cell adenoma

[Term]
id: MT:0003366
name: circulating glucocorticoid level
namespace: Trait.ontology
def: "aberrant blood concentration of the corticosteroids regulating carbohydrate metabolism and exhibiting anti-inflammatory activity" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
subset: slim_pig
is_a: MT:0005418 ! circulating hormone level

[Term]
id: MT:0003369
name: circulating estrogen level
namespace: Trait.ontology
def: "aberration in the blood concentration of any substance that causes development of the female reproductive organs and secondary sexual characteristics" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005418 ! circulating hormone level

[Term]
id: MT:0003372
name: circulating mineralcorticoid level
namespace: Trait.ontology
def: "aberrant blood concentration of corticosteroids that influence water and electrolyte metabolism and balance " [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal circulating mineralocorticoid level" EXACT []
is_a: MT:0005418 ! circulating hormone level

[Term]
id: MT:0003375
name: menstrual cycle (sensu H. sapiens)
namespace: Trait.ontology
def: "a recurring cycle in human primates in which the endometrial lining of the uterus prepares for pregnancy and ovulation occurs; if pregnancy does not occur the lining is discharged at menstruation" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003699 ! female reproductive system physiology

[Term]
id: MT:0003376
name: amenorrhea (sensu H. sapiens)
namespace: Trait.ontology
def: "absence or abnormal cessation of the shedding of the endometrium and associated bleeding in primates" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
synonym: "absent menstruation" EXACT []
is_a: MT:0003375 ! menstrual cycle (sensu H. sapiens)

[Term]
id: MT:0003377
name: onset of menarche
namespace: Trait.ontology
def: "the onset of menstrual cycles occurs at a later age than normal" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001938 ! time of sexual maturation

[Term]
id: MT:0003380
name: intestine regeneration
namespace: Trait.ontology
def: "deviation from the normal ability of the intestine to regenerate healthy tissue following injury" [J:93428, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001663 ! digestive system physiology

[Term]
id: MT:0003381
name: vitreal fibroplasia
namespace: Trait.ontology
def: "production of excess fibrous tissue in the vitreous body of the eye" [brs:Beverly Richards-Smith_Mouse Genome Informatics Curator]
is_a: MT:0002699 ! vitreous body

[Term]
id: MT:0003382
name: tail position
namespace: Trait.ontology
is_a: MT:0001391 ! tail movements

[Term]
id: MT:0003383
name: gluconeogenesis
namespace: Trait.ontology
def: "anomaly in the formation of glucose from non-carbohydrates, such as proteins or fat" [J:93896]
is_a: MT:0002078 ! glucose homeostasis

[Term]
id: MT:0003384
name: ventral body wall morphology
namespace: Trait.ontology
def: "malformation in the anterior portion of a human body or the lower surface of an animal body comprised of ectoderm and mesoderm layers that encloses the body cavity" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
synonym: "ventral body wall defects" EXACT []
is_a: MT:0003385 ! body wall morphology

[Term]
id: MT:0003385
name: body wall morphology
namespace: Trait.ontology
def: "malformation in the external portion of an animal body comprised of ectoderm and mesoderm layers that encloses the body cavity " [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002085 ! embryonic tissue morphology

[Term]
id: MT:0003387
name: aorta patency
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the openness of the main trunk of the systemic arteries" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "aortic patency" RELATED []
relationship: part_of MT:0007044 ! aorta integrity

[Term]
id: MT:0003390
name: lymphedema
namespace: Trait.ontology
def: "abnormal swelling in the soft tissues of the limbs, or less often the trunk, caused by the buildup of lymph fluid" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001785 ! edema

[Term]
id: MT:0003391
name: myxoma
namespace: Trait.ontology
def: "a benign tumor composed of connective tissue embedded in mucus" [smb:Susan M. Bello_Mouse Genome Informatics Curator, Taber's Cyclopedic Medical Dictionary_19th edition:ISBN N 0-8036-0655-99]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0003392
name: atrial myxoma
namespace: Trait.ontology
def: "a primary intracardiac tumor occurring in either the left or right atrium" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003391 ! myxoma

[Term]
id: MT:0003395
name: subclavian artery integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the subclavaian arteries; the right subclavian artery extends from the brachiocephalic artery to the right side of the body, the left subclavian artery extends from the aortic arch to the left side of the body." [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0003410 ! artery integrity

[Term]
id: MT:0003396
name: embryonic hematopoiesis
namespace: Trait.ontology
def: "anomaly in the development of primarily large, nucleated erythroblasts as well as some megakaryocytes and primitive macrophages occurring in blood islands in the yolk sac, generally occurs from E7-E11 in the mouse and through 10 weeks in humans" [J:94136, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal primitive erythropoiesis" EXACT []
synonym: "abnormal primitive hematopoiesis" EXACT []
is_a: MT:0002086 ! extraembryonic tissue morphology
is_a: MT:0002429 ! blood cell morphology/development

[Term]
id: MT:0003398
name: skeletal muscle size
namespace: Trait.ontology
def: "greater than average dimensions of one or more of the muscles of the skeleton" [J:94134, smb:Susan M. Bello_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0000759 ! skeletal muscle morphology

[Term]
id: MT:0003399
name: skeletal muscle fiber size
namespace: Trait.ontology
def: "increase in the size of the large multinucleated cells that make up the skeletal muscles" [J:94134, smb:Susan M. Bello_Mouse Genome Informatics Curator]
subset: slim_pig
is_a: MT:0003084 ! skeletal muscle fiber morphology

[Term]
id: MT:0003400
name: kinked neural tube
namespace: Trait.ontology
def: "twists or kinks in the embryonic neural tube" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:66514]
is_a: MT:0002151 ! neural tube morphology/development

[Term]
id: MT:0003401
name: tail bud size
namespace: Trait.ontology
def: "increased size or area of the primordial region of the embryo that arises to form the tail of the adult" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0002861 ! tail bud morphology

[Term]
id: MT:0003402
name: liver weight
namespace: Trait.ontology
def: "reduced average weight of the bile-secreting exocrine gland" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
subset: slim_chkn
subset: slim_pig
is_a: MT:0000598 ! liver morphology

[Term]
id: MT:0003405
name: platelet shape
namespace: Trait.ontology
def: "change in the normal small, disk-like shape of blood plasma cells derived from megakaryocytes and which function to promote blood clotting" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0000228 ! thrombopoiesis

[Term]
id: MT:0003407
name: CNS regeneration
namespace: Trait.ontology
def: "changes in the ability or inability of healthy central nervous system tissue to regenerate following injury or disease" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0003409
name: hypertrophic chondrocyte zone width
namespace: Trait.ontology
def: "decreased width of cartilage cell matrix layer " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000165 ! hypertrophic chondrocyte zone morphology

[Term]
id: MT:0003410
name: artery integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the blood vessels that carry blood away from the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "arterial integrity" RELATED []
is_a: MT:0000088 ! blood vessel integrity
relationship: part_of MT:0002191 ! artery morphology

[Term]
id: MT:0003412
name: afterhyperpolarization
namespace: Trait.ontology
def: "anomaly in the currents that follow an action potential and influence firing frequency and neuronal integration" [J:94941, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal AHP" EXACT []
is_a: MT:0002272 ! nervous system electrophysiology

[Term]
id: MT:0003413
name: hair follicle integrity
namespace: Trait.ontology
def: "a retrogressive impairment of function or destruction of the hair follicle" [J:94517, monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0000375 ! hair follicle structure

[Term]
id: MT:0003414
name: epidermal cyst
namespace: Trait.ontology
def: "a cyst formed of a mass of epidermal cells which is present beneath the epidermis; the wall is lined with stratified squamous epithelium and exhibits increased/abnormal keratinization" [MeSH:National Library of Medicine_Medical Subject Headings, monikat:Monika Tomczuk_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001191 ! skin condition

[Term]
id: MT:0003415
name: priapism
namespace: Trait.ontology
def: "prolonged penile erection, often painful and without sexual desire" [MeSH:National Library of Medicine_Medical Subject Headings, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001379 ! penile erection function

[Term]
id: MT:0003419
name: onset of endochondral bone ossification
namespace: Trait.ontology
def: "late onset of bone formation in bones that form from cartilage" [J:94631, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000060 ! onset of bone ossification

[Term]
id: MT:0003420
name: onset of intramembranous bone ossification
namespace: Trait.ontology
def: "late onset of bone formation in bones that form without a cartilaginous intermediate including the cranium and clavicle" [J:94631, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000060 ! onset of bone ossification

[Term]
id: MT:0003421
name: thyroid gland development
namespace: Trait.ontology
def: "failure or abnormality in the formation of the thyroid gland during organogenesis" [J:95017, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000681 ! thyroid gland morphology

[Term]
id: MT:0003422
name: thrombolysis
namespace: Trait.ontology
def: "altered ability to break up (lyse) blood clots that are restricting the blood flow" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:17427]
is_a: MT:0002551 ! blood coagulation

[Term]
id: MT:0003424
name: neuronal precursor differentiation
namespace: Trait.ontology
def: "earlier than normal transformation of neuronal precursor cells into neurons" [J:94391, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006008 ! neurogenesis

[Term]
id: MT:0003425
name: optic vesicle formation
namespace: Trait.ontology
def: "anomalous formation of the hollow outgrowth from the lateral aspects of the embryonic forebrain from which the retina and optic nerve develop" [J:94391, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001286 ! eye development

[Term]
id: MT:0003426
name: pulmonary interstitial fibrosis
namespace: Trait.ontology
def: "formation of fibrous tissue within the interstices of the lung as a result of repair or a reactive process" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:63134]
is_a: MT:0002276 ! lung interstitium morphology
is_a: MT:0006050 ! pulmonary fibrosis

[Term]
id: MT:0003427
name: parakeratosis
namespace: Trait.ontology
def: "abnormal retention of the nuclei of the keratinocytes in the stratum corneum of the epidermis" [smb:Susan M. Bello_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001240 ! cornified layer morphology

[Term]
id: MT:0003429
name: response to growth hormone
namespace: Trait.ontology
def: "no growth response to exogenous growth hormone" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003638 ! response/metabolism to endogenous compounds

[Term]
id: MT:0003430
name: islet cell adenoma
namespace: Trait.ontology
def: "a benign epithelial neoplasm with a glandular organization present in islet cells of the pancreas" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0002815 ! adenoma

[Term]
id: MT:0003431
name: parathyroid gland physiology
namespace: Trait.ontology
def: "anomalous function of this paired endocrine gland that normally produces parathyroid hormone (PTH) that regulates calcium and phosphorous metabolism" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0002164 ! gland physiology

[Term]
id: MT:0003435
name: herniated seminal glands
namespace: Trait.ontology
def: "protrusion of the seminal vesicles through the pelvic outlet" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:73613]
synonym: "herniated seminal vesicles" EXACT []
is_a: MT:0002059 ! seminal gland morphology

[Term]
id: MT:0003436
name: resistance to induced arthritis
namespace: Trait.ontology
def: "less likely to be stricken with changes in the synovial membranes and thickening of articular structures, widespread degeneration of the collagen fibers in connective tissues, and by atrophy and rarefaction of bony structures that are induced by inflammatory responses caused by chemical or mechanical agents" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:75303]
is_a: MT:0002993 ! arthritis

[Term]
id: MT:0003437
name: carotid body morphology
namespace: Trait.ontology
def: "any malformation in a small epithelioid structure consisting of a small cluster of chemoreceptive and supporting cells located near the bifurcation of the common carotid artery that serves as a chemoreceptive organ that senses the pH, carbon dioxide, and oxygen concentrations in the blood and plays a crucial role in their homeostatic control" [MeSH:National Library of Medicine_Medical Subject Headings, monikat:Monika Tomczuk_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001001 ! chemoreceptor morphology

[Term]
id: MT:0003438
name: carotid body activity
namespace: Trait.ontology
def: "function of a small epithelioid structure consisting of a small cluster of chemoreceptive and supporting cells located near the bifurcation of the common carotid artery that serves as a chemoreceptive organ that senses the pH, carbon dioxide, and oxygen concentrations in the blood and plays a crucial role in their homeostatic control" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0001544 ! cardiovascular system physiology

[Term]
id: MT:0003439
name: glycerol level
namespace: Trait.ontology
def: "anomalous concentration of this molecule, the backbone of lipids, which is important for gluconeogenesis during starvation" [J:95278, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001547 ! lipid level

[Term]
id: MT:0003442
name: circulating glycerol level
namespace: Trait.ontology
def: "lower than normal concentration of glycerol in the blood" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003439 ! glycerol level
is_a: MT:0003949 ! circulating lipid level

[Term]
id: MT:0003444
name: neurotransmitter uptake
namespace: Trait.ontology
def: "aberration in the reabsorbtion of endogenous signaling molecules normally taken in by neurons that alter the behavior of neurons or effector cells" [J:95639, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002204 ! neurotransmitter level

[Term]
id: MT:0003445
name: sirenomelia
namespace: Trait.ontology
def: "fusion of the posterior limbs often with partial or complete fusion of the autopods" [J:67375]
is_a: MT:0005221 ! rostral-caudal axis patterning

[Term]
id: MT:0003446
name: kidney cell number
namespace: Trait.ontology
def: "decreased cell number in the kidney leading to reduced size" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
synonym: "hypoplastic kidney" EXACT []
synonym: "kidney hypoplasia" EXACT []
is_a: MT:0002706 ! kidney size

[Term]
id: MT:0003448
name: tumor morphology
namespace: Trait.ontology
def: "changes in the expected pathology for a given tumor type compared to controls" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "abnormal tumor morphology" EXACT []
synonym: "altered tumor characteristics" EXACT []
is_a: MT:0002166 ! tumor susceptibility

[Term]
id: MT:0003449
name: intestinal goblet cell morphology
namespace: Trait.ontology
def: "malformation of the unicellular mucin-secreting glands" [J:95282, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000511 ! intestinal mucosa morphology

[Term]
id: MT:0003450
name: pancreas size
namespace: Trait.ontology
def: "increase of the size of the pancreas compared to controls" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001944 ! pancreas morphology

[Term]
id: MT:0003452
name: parotid gland morphology
namespace: Trait.ontology
def: "malformation of either of the largest of the major salivary glands situated below and in front of each ear and opening into the parotid duct" [J:94478, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003792 ! major salivary gland morphology

[Term]
id: MT:0003453
name: keratinocyte physiology
namespace: Trait.ontology
def: "atypical function of the cells of the epidermis that produce keratin" [J:94860, monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0005501 ! skin physiology

[Term]
id: MT:0003454
name: erythroderma
namespace: Trait.ontology
def: "exfoliation and widespread, intense reddening of the skin due to inflammatory skin disease" [J:95549, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001194 ! dermatitis

[Term]
id: MT:0003455
name: resistance to induced retinal damage
namespace: Trait.ontology
def: "reduced or absent pathological changes in the retina due to chemical or mechanical agents" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:93533]
is_a: MT:0001325 ! retina morphology

[Term]
id: MT:0003456
name: tail size
namespace: Trait.ontology
alt_id: MT:0005080
def: "length, width or volume of the appendage at the caudal end of the vertebral column " [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "tail less" EXACT []
synonym: "tailless" EXACT []
is_a: MT:0002111 ! tail morphology

[Term]
id: MT:0003457
name: circulating ketone body level
namespace: Trait.ontology
def: "aberrant amount of acetoacetate, 3-hydroxybutyrate and acteone in the blood; produced by fatty acid and carbohydrate metabolism and seen in conditions such as starvation and diabetes mellitus" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003949 ! circulating lipid level

[Term]
id: MT:0003461
name: response to novel object
namespace: Trait.ontology
is_a: MT:0003107 ! response to novelty

[Term]
id: MT:0003462
name: response to novel odor
namespace: Trait.ontology
is_a: MT:0003107 ! response to novelty

[Term]
id: MT:0003463
name: single cell response
namespace: Trait.ontology
def: "altered values from controls obtained upon extra- or intracellular recordings from single cells" [Nmice:Neuromice Consortium Submission]
is_a: MT:0002272 ! nervous system electrophysiology

[Term]
id: MT:0003464
name: single cell response threshold
namespace: Trait.ontology
def: "any change in the value at which a stimulus first elicits a recordable response recorded in a single cell" [Nmice:Neuromice Consortium Submission]
is_a: MT:0003463 ! single cell response

[Term]
id: MT:0003467
name: single cell response intensity
namespace: Trait.ontology
def: "any change in the value for changes in the degree of de- or hyperpolarization or number of action potentials in response to a specific stimulus recorded in a single cell" [Nmice:Neuromice Consortium Submission]
is_a: MT:0003463 ! single cell response

[Term]
id: MT:0003470
name: summary potential
namespace: Trait.ontology
def: "anomaly in the electrophysiological recording of the activity of several cells" [Nmice:Neuromice Consortium Submission]
is_a: MT:0002272 ! nervous system electrophysiology

[Term]
id: MT:0003471
name: summary potential threshold
namespace: Trait.ontology
def: "any change in the value at which a stimulus first elicits a recordable response recorded in several cells or a tissue slice" [Nmice:Neuromice Consortium Submission]
is_a: MT:0003470 ! summary potential

[Term]
id: MT:0003474
name: summary potential intensity
namespace: Trait.ontology
def: "any change in the value for changes in the degree of de- or hyperpolarization or number of action potentials in response to a specific stimulus recorded in several cells or a tissue slice" [Nmice:Neuromice Consortium Submission]
is_a: MT:0003470 ! summary potential

[Term]
id: MT:0003477
name: nerve fiber response
namespace: Trait.ontology
def: "anomaly in the electrophysiological recordings from a single or several nerve fiber(s)" [Nmice:Neuromice Consortium Submission]
is_a: MT:0002272 ! nervous system electrophysiology

[Term]
id: MT:0003478
name: nerve fiber response threshold
namespace: Trait.ontology
def: "any change in the value at which a stimulus first elicits a recordable response recorded in a single or several nerve fiber(s)" [Nmice:Neuromice Consortium Submission]
is_a: MT:0003477 ! nerve fiber response

[Term]
id: MT:0003479
name: nerve fiber response intensity
namespace: Trait.ontology
def: "any change in the value for changes in the degree of de- or hyperpolarization or number of action potentials in response to a specific stimulus recorded in a single or several nerve fiber(s)" [Nmice:Neuromice Consortium Submission]
is_a: MT:0003477 ! nerve fiber response

[Term]
id: MT:0003484
name: channel response
namespace: Trait.ontology
alt_id: MT:0002203
def: "anomalies in the electrophysiological recordings from ion channels" [Nmice:Neuromice Consortium Submission]
synonym: "channel defects" EXACT []
is_a: MT:0002272 ! nervous system electrophysiology
is_a: MT:0003635 ! synaptic transmission

[Term]
id: MT:0003485
name: channel response threshold
namespace: Trait.ontology
def: "any change in the value at which a stimulus first elicits a recordable response recorded from ion channels" [Nmice:Neuromice Consortium Submission]
is_a: MT:0003484 ! channel response

[Term]
id: MT:0003486
name: channel response intensity
namespace: Trait.ontology
def: "any change in the value for changes in the degree of de- or hyperpolarization or number of action potentials in response to a specific stimulus recorded from ion channels" [Nmice:Neuromice Consortium Submission]
is_a: MT:0003484 ! channel response

[Term]
id: MT:0003491
name: voluntary movement
namespace: Trait.ontology
subset: slim_pig
is_a: MT:0002066 ! motor capabilities/coordination/movement

[Term]
id: MT:0003492
name: involuntary movement
namespace: Trait.ontology
is_a: MT:0002066 ! motor capabilities/coordination/movement

[Term]
id: MT:0003495
name: parathyroid adenoma
namespace: Trait.ontology
def: "appearance of benign neoplasms in the parathyroid gland" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0002815 ! adenoma

[Term]
id: MT:0003496
name: thyroid adenoma
namespace: Trait.ontology
def: "appearance of benign neoplasms in the thyroid gland" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0002815 ! adenoma

[Term]
id: MT:0003497
name: response to parathyroid hormone
namespace: Trait.ontology
def: "no changes in calcium homeostasis in response to endogenous or exogenous hormone" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003638 ! response/metabolism to endogenous compounds

[Term]
id: MT:0003498
name: thyroid gland cell number
namespace: Trait.ontology
def: "increased size due to increased cell number of the endocrine gland located in the front and to the sides of the upper part of the trachea and which secretes thyroid hormone and calcitonin" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005355 ! thyroid gland size

[Term]
id: MT:0003501
name: iodide oxidation
namespace: Trait.ontology
def: "thyroid defect in oxidation and organification of iodide" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0002876 ! thyroid physiology

[Term]
id: MT:0003504
name: thyroid inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the thyroid gland" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001846 ! tissue specific inflammatory response
is_a: MT:0002876 ! thyroid physiology

[Term]
id: MT:0003505
name: prolactinoma
namespace: Trait.ontology
def: "a pituitary adenoma characterized by secretion of prolactin" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0002041 ! pituitary adenoma

[Term]
id: MT:0003506
name: growth hormone secretion
namespace: Trait.ontology
def: "excessive secretion of growth hormone resulting in progressive enlargement of the face, hands, feet, head, and thorax; organomegaly and impaired glucose homeostasis may ensue" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "increased growth hormone secretion" EXACT []
is_a: MT:0001746 ! pituitary secretion

[Term]
id: MT:0003507
name: ovary physiology
namespace: Trait.ontology
def: "anomaly or loss either the production of female germ cells or the endocrine cells for the production of estrogen and progesterone" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0005647 ! sex gland physiology

[Term]
id: MT:0003508
name: circulating levels of dihydrotestosterone
namespace: Trait.ontology
def: "aberration in the blood concentration of this potent androgenic metabolite of testosterone" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
synonym: "abnormal circulating level of stanolone" EXACT []
is_a: MT:0005418 ! circulating hormone level

[Term]
id: MT:0003511
name: labium morphology
namespace: Trait.ontology
def: "malformation of the folds of skin which form the inner lips (labia minora) and outer lips (labia majora) on both sides of the vaginal opening " [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003126 ! vulva morphology

[Term]
id: MT:0003512
name: labia size
namespace: Trait.ontology
def: "increased size of the folds of skin which form the inner lips (labia minora) and outer lips (labia majora) on both sides of the vaginal opening " [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003511 ! labium morphology

[Term]
id: MT:0003514
name: interlabial sulcus
namespace: Trait.ontology
def: "the presence of grooves or furrows in the folds of skin which lips on both sides of the vaginal opening " [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003511 ! labium morphology

[Term]
id: MT:0003515
name: labia majora morphology
namespace: Trait.ontology
def: "malformation of the folds of skin which form the outer lips (labia majora) on both sides of the vaginal opening " [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003511 ! labium morphology

[Term]
id: MT:0003517
name: labia majora size
namespace: Trait.ontology
def: "increased size of the folds of skin which form the outer lips (labia majora) on both sides of the vaginal opening" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003512 ! labia size
is_a: MT:0003515 ! labia majora morphology

[Term]
id: MT:0003519
name: labia majora shape
namespace: Trait.ontology
def: "appearance of the folds of skin which form the outer lips (labia majora) on both sides of the vaginal opening" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003515 ! labia majora morphology

[Term]
id: MT:0003520
name: labia minora morphology
namespace: Trait.ontology
def: "malformation of the folds of skin which form the inner lips (labia minora) on both sides of the vaginal opening " [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003511 ! labium morphology

[Term]
id: MT:0003522
name: labia minora size
namespace: Trait.ontology
def: "increased size of the folds of skin which form the inner lips (labia minora) on both sides of the vaginal opening " [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003512 ! labia size
is_a: MT:0003520 ! labia minora morphology

[Term]
id: MT:0003524
name: labia minora shape
namespace: Trait.ontology
def: "appearance of the folds of skin which form the inner lips (labia minora) on both sides of the vaginal opening " [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003520 ! labia minora morphology

[Term]
id: MT:0003525
name: vulval warts
namespace: Trait.ontology
def: "benign epithelial growths of the external genitalia of the female" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003126 ! vulva morphology

[Term]
id: MT:0003526
name: vulval cysts
namespace: Trait.ontology
def: "cystic vulva; usually refers to a benign growth" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003126 ! vulva morphology

[Term]
id: MT:0003528
name: vulva size
namespace: Trait.ontology
def: "increased size of the external genitalia of the female" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003126 ! vulva morphology

[Term]
id: MT:0003529
name: clitoris size
namespace: Trait.ontology
def: "increased size of the small, erectile body located at the anterior end of the vulva" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003127 ! clitoris morphology

[Term]
id: MT:0003531
name: vagina development
namespace: Trait.ontology
def: "abnormal morphogenesis of the female reproductive canal located between the uterus and the vulva" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001139 ! vagina morphology
is_a: MT:0003936 ! reproductive system development

[Term]
id: MT:0003532
name: rudimentary vagina
namespace: Trait.ontology
def: "not fully developed or remnant of the female reproductive canal located between the uterus and the vulva" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003531 ! vagina development

[Term]
id: MT:0003533
name: bifid vagina
namespace: Trait.ontology
def: "cleft of the female reproductive canal located between the uterus and the vulva into two parts or branches" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "double vagina" EXACT []
is_a: MT:0003531 ! vagina development

[Term]
id: MT:0003534
name: blind vagina
namespace: Trait.ontology
def: "presence the female reproductive canal that ends in a sac and does not connect to internal genitalia" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, ncbi:Matthew Mailman_NCBI request]
comment: this is our best guess at the definition of this term based on other similar terms--csmith
is_a: MT:0003531 ! vagina development

[Term]
id: MT:0003536
name: vaginal dryness
namespace: Trait.ontology
def: "lack of the normal presence or reduced presence of secretions in the vagina" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001139 ! vagina morphology

[Term]
id: MT:0003537
name: hydrometrocolops
namespace: Trait.ontology
def: "collection of fluid in the vagina; often due to a congenital obstruction" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001139 ! vagina morphology

[Term]
id: MT:0003538
name: hymen development
namespace: Trait.ontology
def: "anomaly in the morphogenesis of the thin membrane which may partially occlude the opening of the vagina; often absent in normal females" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001142 ! vaginal opening

[Term]
id: MT:0003541
name: vaginal inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the vagina" [ncbi:Matthew Mailman_NCBI request]
synonym: "vaginitis" EXACT []
is_a: MT:0001139 ! vagina morphology
is_a: MT:0001846 ! tissue specific inflammatory response

[Term]
id: MT:0003547
name: pulmonary pressure
namespace: Trait.ontology
def: "tension of the blood within the pulmonary arteries" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0002295 ! pulmonary circulation

[Term]
id: MT:0003550
name: short perineum
namespace: Trait.ontology
def: "reduced length of the area between the genital organs and the anus that lies beneath the pelvic diaphragm" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0005189 ! anogenital distance

[Term]
id: MT:0003551
name: blind perineal pouch
namespace: Trait.ontology
def: "opening in the perineum leading to a blind-ending sac " [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003315 ! perineum morphology

[Term]
id: MT:0003552
name: vaginal cysts
namespace: Trait.ontology
def: "benign epithelial growths of the female reproductive canal located between the uterus and the vulva" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001139 ! vagina morphology

[Term]
id: MT:0003553
name: foreskin morphology
namespace: Trait.ontology
def: "anomaly of the loose fold of skin that covers the penis" [ncbi:Matthew Mailman_NCBI request]
synonym: "abnormal prepuce" EXACT []
is_a: MT:0005187 ! penis morphology

[Term]
id: MT:0003554
name: phimosis
namespace: Trait.ontology
def: "narrow opening of the foreskin resulting in the inability to retract the foreskin over the glans penis " [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003553 ! foreskin morphology

[Term]
id: MT:0003555
name: chordee
namespace: Trait.ontology
def: "acute angulation of the penis upon erection; often painful and due to disease or congenital malformation" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003698 ! male reproductive system physiology

[Term]
id: MT:0003559
name: bifid uterus
namespace: Trait.ontology
def: "cleft of the female muscular organ of gestation into two parts or branches, often having the appearance of two lobes" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001120 ! uterus morphology

[Term]
id: MT:0003560
name: osteoarthritis
namespace: Trait.ontology
def: "a type of arthritis that is caused by the breakdown and eventual loss of the cartilage of one or more joints" [J:95374, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002993 ! arthritis

[Term]
id: MT:0003561
name: rheumatoid arthritis
namespace: Trait.ontology
def: "an autoimmune disease that causes chronic inflammation of the joints and may also cause inflammation of the tissue around the joints, as well as other organs in the body" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002993 ! arthritis

[Term]
id: MT:0003562
name: pancreatic beta cell physiology
namespace: Trait.ontology
def: "anomaly in the function of the insulin-producing cells of the islets of Langerhans in the pancreas" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002693 ! pancreas physiology

[Term]
id: MT:0003563
name: pancreatic alpha cell physiology
namespace: Trait.ontology
def: "anomaly in the function of the glucagon-producing cells of the islets of Langerhans in the pancreas" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002693 ! pancreas physiology

[Term]
id: MT:0003564
name: insulin secretion
namespace: Trait.ontology
def: "aberrant release of this hormone secreted by beta cells of the pancreas, that promotes glucose utilization, protein synthesis, and the formation and storage of neutral lipids " [MeSH:National Library of Medicine_Medical Subject Headings, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002694 ! pancreas secretion
is_a: MT:0003562 ! pancreatic beta cell physiology

[Term]
id: MT:0003565
name: glucagon secretion
namespace: Trait.ontology
def: "anomaly in the release of this hormone secreted by the alpha cells of the islets of Langerhans; it normally plays a role in regulation of blood glucose concentration, ketone metabolism, and other biochemical and physiological processes" [MeSH:National Library of Medicine_Medical Subject Headings, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002694 ! pancreas secretion
is_a: MT:0003563 ! pancreatic alpha cell physiology

[Term]
id: MT:0003566
name: cell adhesion
namespace: Trait.ontology
def: "altered ability of a cell to adhere to another cell or to a non-cellular component of the environment" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0005621 ! cell physiology

[Term]
id: MT:0003568
name: uterine lumen morphology
namespace: Trait.ontology
def: "congenital absence of the normal opening or lumen of the uterus" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "uterus atresia" EXACT []
is_a: MT:0001120 ! uterus morphology

[Term]
id: MT:0003569
name: leiomyoma
namespace: Trait.ontology
def: "a benign tumor derived from smooth (nonstriated) muscle " [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "fibroid tumor" EXACT []
synonym: "fibromyoma" EXACT []
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0003570
name: uterine leiomyoma
namespace: Trait.ontology
def: "a benign tumor derived from the smooth muscle tissue of the uterus" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
synonym: "fibroid uterus" EXACT []
synonym: "uterine fibroids" EXACT []
is_a: MT:0003569 ! leiomyoma

[Term]
id: MT:0003571
name: uterine rupture
namespace: Trait.ontology
def: "tearing of the uterine tissue; may be due to trauma or pregnancy complications" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
synonym: "rupture of uterus" EXACT []
is_a: MT:0001120 ! uterus morphology

[Term]
id: MT:0003572
name: uterus development
namespace: Trait.ontology
def: "abnormal morphogenesis of the female muscular organ of gestation" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001120 ! uterus morphology
is_a: MT:0003936 ! reproductive system development

[Term]
id: MT:0003573
name: rudimentary uterus
namespace: Trait.ontology
def: "not fully developed or remnant of the female muscular organ of gestation" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003572 ! uterus development

[Term]
id: MT:0003574
name: oviduct morphology
namespace: Trait.ontology
def: "malformation of the tube through which the ova pass from the ovary to the uterus" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal fallopian tube morphology" EXACT []
is_a: MT:0001119 ! female reproductive anatomy

[Term]
id: MT:0003576
name: oviduct size
namespace: Trait.ontology
def: "reduced size of the tube through which the ova pass from the ovary to the uterus due to decreased cell number" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "fallopian tube hypoplasia" EXACT []
is_a: MT:0003574 ! oviduct morphology

[Term]
id: MT:0003577
name: rudimentary oviduct
namespace: Trait.ontology
def: "not fully developed or remnant of the tube through which the ova pass from the ovary to the uterus" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "rudimentary fallopian tubes" EXACT []
is_a: MT:0003574 ! oviduct morphology

[Term]
id: MT:0003579
name: ovarian carcinoma
namespace: Trait.ontology
def: "malignant neoplasm arising from ovarian tissue" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0002038 ! carcinoma

[Term]
id: MT:0003580
name: fibroma
namespace: Trait.ontology
def: "a benign tumor of fibrous or fully developed connective tissue " [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0003581
name: ovarian fibroma
namespace: Trait.ontology
def: "a benign tumor of the ovary" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003580 ! fibroma

[Term]
id: MT:0003582
name: ovary development
namespace: Trait.ontology
def: "abnormal morphogenesis of the female reproductive gland containing the germ cells" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0001126 ! ovary morphology
is_a: MT:0003936 ! reproductive system development

[Term]
id: MT:0003583
name: rudimentary ovary
namespace: Trait.ontology
def: "not fully developed or remnant of the female reproductive gland containing the germ cells" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0003582 ! ovary development

[Term]
id: MT:0003584
name: bifid ureter
namespace: Trait.ontology
def: "cleft of the ureter into two parts or branches" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000534 ! ureter morphology

[Term]
id: MT:0003585
name: ureter size
namespace: Trait.ontology
def: "increased size or length of the tube that conducts the urine from the renal pelvis to the bladder" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "megaureter" EXACT []
is_a: MT:0000534 ! ureter morphology

[Term]
id: MT:0003586
name: ureter dilation
namespace: Trait.ontology
def: "abnormal distention of the ureter due to accumulation of fluid" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000534 ! ureter morphology

[Term]
id: MT:0003587
name: ureter obstruction
namespace: Trait.ontology
def: "any impediment, blockage, or reversal of the normal flow of the urine towards the bladder" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000534 ! ureter morphology

[Term]
id: MT:0003588
name: ureter stenosis
namespace: Trait.ontology
def: "abnormal narrowing or constriction of the ureter" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003585 ! ureter size

[Term]
id: MT:0003589
name: ureter physiology
namespace: Trait.ontology
def: "anomalous function of the tube that conducts the urine from the renal pelvis to the bladder" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0005502 ! urinary system physiology

[Term]
id: MT:0003590
name: ureteral reflux
namespace: Trait.ontology
def: "retrograde movement of urine from the bladder to the kidney" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003589 ! ureter physiology

[Term]
id: MT:0003591
name: urethra atresia
namespace: Trait.ontology
def: "closure, or failure to develop a connection in the canal that leads from the bladder and discharges urine externally" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000537 ! urethra morphology

[Term]
id: MT:0003592
name: urethra stenosis
namespace: Trait.ontology
def: "abnormal narrowing or constriction of the urethra" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000537 ! urethra morphology

[Term]
id: MT:0003593
name: urethrovaginal fistula
namespace: Trait.ontology
def: "an abnormal anatomical passage connecting the urethra and the vagina" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000537 ! urethra morphology
is_a: MT:0001139 ! vagina morphology

[Term]
id: MT:0003594
name: urethra size
namespace: Trait.ontology
def: "decreased size or length of the canal that leads from the bladder and discharges urine externally" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000537 ! urethra morphology

[Term]
id: MT:0003595
name: epididymal cyst
namespace: Trait.ontology
def: "benign growths present in the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0002631 ! epididymis morphology

[Term]
id: MT:0003596
name: epididymal inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001846 ! tissue specific inflammatory response

[Term]
id: MT:0003597
name: epididymal cystademona
namespace: Trait.ontology
def: "a benign epithelial neoplasm with a glandular organization arising from epididymal tissue" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002815 ! adenoma

[Term]
id: MT:0003598
name: epispadias
namespace: Trait.ontology
def: "congenital absence of the upper wall of the urethra" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000537 ! urethra morphology
is_a: MT:0005187 ! penis morphology

[Term]
id: MT:0003599
name: penis size
namespace: Trait.ontology
def: "enlarged size of the organ of copulation and urination in the male" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005187 ! penis morphology

[Term]
id: MT:0003600
name: ectopic kidney
namespace: Trait.ontology
def: "kidney located in a position not normally occupied by this tissue" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0002135 ! kidney morphology

[Term]
id: MT:0003601
name: bifid kidney
namespace: Trait.ontology
def: "cleft of the kidney into two parts or branches, often having the appearance of two lobes" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003650 ! kidney shape

[Term]
id: MT:0003602
name: renal hamartoma
namespace: Trait.ontology
def: "a benign formation of a mass of tissue of disproportionate size and distribution in the kidney, but composed of an overgrowth of mature cells and tissues that normally occur in this tissue" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0003603
name: renal hemangioblastoma
namespace: Trait.ontology
def: "a benign cyst-like tumor of the kidney that is composed of multiple capillary and sinusoidal channels lined with endothelial cells " [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0003604
name: single kidney
namespace: Trait.ontology
def: "presence of  only one of the paired organs responsible for urine secretion" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000527 ! kidney development

[Term]
id: MT:0003605
name: fused kidneys
namespace: Trait.ontology
def: "a defect in which there is a single malformed organ resulting from partial or complete fusion of the two renal anlage" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "cake kidney" NARROW []
synonym: "disk kidney" NARROW []
synonym: "horseshoe kidney" NARROW []
is_a: MT:0000527 ! kidney development

[Term]
id: MT:0003606
name: kidney function
namespace: Trait.ontology
def: "cessation of renal function" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0002136 ! kidney physiology

[Term]
id: MT:0003607
name: prostate physiology
namespace: Trait.ontology
def: "malfunction of the gland in males that secretes part of the seminiferous fluid" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003698 ! male reproductive system physiology
is_a: MT:0005647 ! sex gland physiology

[Term]
id: MT:0003608
name: prostate inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the prostate" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0001846 ! tissue specific inflammatory response
is_a: MT:0002254 ! reproductive system inflammation
is_a: MT:0003607 ! prostate physiology

[Term]
id: MT:0003610
name: scrotum cell number
namespace: Trait.ontology
def: "increase in size, usually due to an increase in cell number, of the external sac of skin that encloses the testes" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001150 ! scrotum size

[Term]
id: MT:0003612
name: bifid scrotum
namespace: Trait.ontology
def: "cleft of the scrotum into two parts or branches, often having the appearance of two lobes " [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0002669 ! scrotum morphology

[Term]
id: MT:0003613
name: kidney medulla development
namespace: Trait.ontology
is_a: MT:0000527 ! kidney development

[Term]
id: MT:0003614
name: urinary bladder prolapse
namespace: Trait.ontology
def: "downward movement, and possible external appearance, of the bladder through the urethra" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000538 ! urinary bladder morphology

[Term]
id: MT:0003615
name: urinary bladder diverticulum
namespace: Trait.ontology
def: "a pouch or sac protruding from the urinary bladder wall" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000538 ! urinary bladder morphology

[Term]
id: MT:0003616
name: urachus
namespace: Trait.ontology
def: "fibrous connection between bladder and umbilicus" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000538 ! urinary bladder morphology
is_a: MT:0001725 ! umbilical cord morphology

[Term]
id: MT:0003617
name: urinary bladder cell number
namespace: Trait.ontology
def: "reduced number of cells comprising the urinary bladder, often resulting in a small size" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000538 ! urinary bladder morphology

[Term]
id: MT:0003618
name: cervical opening size
namespace: Trait.ontology
def: "narrowing of the cervical opening" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001135 ! cervix morphology

[Term]
id: MT:0003619
name: urine color
namespace: Trait.ontology
def: "any alteration from the usual straw-coloration of the urine" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001757 ! urine chemistry

[Term]
id: MT:0003620
name: urine output
namespace: Trait.ontology
def: "decreased volume of urine produced and excreted" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001756 ! urination
is_a: MT:0005555 ! kidney excretion

[Term]
id: MT:0003621
name: dysuria
namespace: Trait.ontology
def: "difficult or painful urination" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001756 ! urination

[Term]
id: MT:0003622
name: incomplete emptying of bladder
namespace: Trait.ontology
def: "upon urination, some urine is retained in the bladder instead of being excreted" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001756 ! urination

[Term]
id: MT:0003623
name: hydrocele
namespace: Trait.ontology
def: "accumulation of fluid around testes" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001146 ! testis morphology

[Term]
id: MT:0003626
name: kidney medulla cell number
namespace: Trait.ontology
def: "decreased size due to increased cell number of the inner portion of the kidney consisting of the renal pyramids" [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003014 ! kidney medulla morphology
is_a: MT:0003446 ! kidney cell number

[Term]
id: MT:0003627
name: lymphocyte rolling
namespace: Trait.ontology
def: "anomaly in the number or velocity of lymphocytes rolling along the luminal aspects of high endothelial venules" [J:95656, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003156 ! lymphocyte migration/homing

[Term]
id: MT:0003628
name: lymphocyte adhesion
namespace: Trait.ontology
def: "anomaly in the number of or process by which lymphocytes adhere to the luminal aspects of high endothelial venules prior to transmigration out of the vessel" [J:95656, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal lymphocyte firm adhesion" EXACT []
is_a: MT:0003156 ! lymphocyte migration/homing

[Term]
id: MT:0003629
name: lymphocyte transmigration
namespace: Trait.ontology
def: "anomaly in the number of or process by which lymphocytes cross out of high endothelial venules into the surrounding tissue" [J:95656, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003156 ! lymphocyte migration/homing

[Term]
id: MT:0003630
name: urothelium
namespace: Trait.ontology
def: "malformation of the mucus lining in organs of the urinary tract, consisting in the bladder of three to seven cell layers" [J:95622, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000516 ! urinary system morphology

[Term]
id: MT:0003631
name: nervous system trait
namespace: Trait.ontology
alt_id: MT:0005368
alt_id: MT:0005383
synonym: "central nervous system phenotype" EXACT []
synonym: "CNS" EXACT []
synonym: "peripheral nervous system phenotype" EXACT []
synonym: "PNS" EXACT []
is_a: MT:0000001 ! Trait

[Term]
id: MT:0003632
name: nervous system morphology
namespace: Trait.ontology
alt_id: MT:0000769
alt_id: MT:0000957
alt_id: MT:0002153
alt_id: MT:0002157
alt_id: MT:0002170
alt_id: MT:0002171
synonym: "abnormal central nervous system morphology" EXACT []
synonym: "abnormal peripheral nervous system" EXACT []
synonym: "abnormal peripheral nervous system morphology" EXACT []
synonym: "central nervous system abnormalities" EXACT []
synonym: "central nervous system defects" EXACT []
synonym: "central nervous system: other dysmorphology" EXACT []
synonym: "other abnormal central nervous system morphology" EXACT []
synonym: "peripheral nervous system abnormalities" EXACT []
synonym: "peripheral nervous system abnormality" EXACT []
synonym: "peripheral nervous system defects" EXACT []
synonym: "peripheral nervous system: dysmorphology" EXACT []
xref: GO:0007417
xref: MGI:2173613
xref: MGI:2173617
is_a: MT:0003631 ! nervous system trait

[Term]
id: MT:0003633
name: nervous system physiology
namespace: Trait.ontology
alt_id: MT:0000945
alt_id: MT:0001887
alt_id: MT:0001910
alt_id: MT:0001918
alt_id: MT:0002155
alt_id: MT:0002158
synonym: "abnormal brain function" NARROW []
synonym: "abnormal central nervous system physiology" NARROW []
synonym: "abnormal peripheral nervous system physiology" NARROW []
synonym: "central nervous system functional abnormalities" NARROW []
synonym: "central nervous system: other functional anomalies" NARROW []
synonym: "peripheral nervous system: functional anomalies" NARROW []
xref: MGI:2173615
xref: MGI:2173618
is_a: MT:0003631 ! nervous system trait

[Term]
id: MT:0003634
name: glia morphology
namespace: Trait.ontology
def: "malformation or absence of non-neuronal cells of the nervous system that form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0003632 ! nervous system morphology

[Term]
id: MT:0003635
name: synaptic transmission
namespace: Trait.ontology
alt_id: MT:0002202
def: "defect in the communication from a neuron to a target across a synapse " [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal neurotransmission" EXACT []
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0003637
name: cochlear ganglion cell number
namespace: Trait.ontology
def: "reduced numbers of the group of nerve cell bodies that conveys auditory sensation from the organ of Corti to the hindbrain and resides on the cochlear part of the vestibulocochlear nerve (eighth cranial nerve)" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "reduced number of spiral ganglion cells" EXACT []
synonym: "spiral ganglion hypoplasia" EXACT []
is_a: MT:0003986 ! cochlear ganglion size

[Term]
id: MT:0003638
name: response/metabolism to endogenous compounds
namespace: Trait.ontology
def: "altered ability or inability to metabolize or respond to substances normally present in the body" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal metabolism of endogenous compounds" EXACT []
is_a: MT:0002121 ! metabolism

[Term]
id: MT:0003639
name: response to vitamins
namespace: Trait.ontology
def: "altered ability or inability to respond to or metabolize a group of organic substances that are required in trace amounts for the normal metabolic homeostasis of the body " [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal metabolism of vitamins" EXACT []
is_a: MT:0003638 ! response/metabolism to endogenous compounds
is_a: MT:0004019 ! vitamin homeostasis

[Term]
id: MT:0003640
name: susceptibility to lung neoplasm
namespace: Trait.ontology
def: "reduced likelihood of developing an abnormal growth of lung tissue" [J:95491, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005514 ! susceptibility to tumor development

[Term]
id: MT:0003641
name: lung size
namespace: Trait.ontology
def: "reduced size of the lung relative to normal" [J:95332, smb:Susan M. Bello_Mouse Genome Informatics Curator]
subset: slim_chkn
is_a: MT:0001175 ! lung morphology

[Term]
id: MT:0003646
name: muscle stamina
namespace: Trait.ontology
def: "increased muscle exhaustion or increased susceptibility to muscle exhaustion" [J:96306]
synonym: "muscle fatigability" EXACT []
is_a: MT:0002106 ! muscle physiology

[Term]
id: MT:0003647
name: oligodendrocyte number
namespace: Trait.ontology
def: "absence of the neuroglia of the central nervous system that form the insulating myelin sheath of axons in the CNS" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0000953 ! oligodendrocyte morphology

[Term]
id: MT:0003648
name: radial glial cell morphology
namespace: Trait.ontology
def: "anomalous structure, number, or composition of the supporting cells of the developing central nervous system that guide neuronal migration during development and exchange metabolites with developing and migrating neurons; these cells differentiate into astrocytes and some neuronal types in the adult" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal radial glia" EXACT []
is_a: MT:0000952 ! CNS glia morphology
is_a: MT:0006008 ! neurogenesis

[Term]
id: MT:0003650
name: kidney shape
namespace: Trait.ontology
def: "alteration in the size, shape or organization of cells of the kidney" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:67732]
synonym: "kidney dysplasia" EXACT []
is_a: MT:0002135 ! kidney morphology

[Term]
id: MT:0003651
name: axon outgrowth
namespace: Trait.ontology
def: "defect/abnormality in the ability of an axon to extend from a neuron cell body" [J:96121, monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0006008 ! neurogenesis

[Term]
id: MT:0003652
name: skin turgor
namespace: Trait.ontology
def: "anomaly in the ability of the skin to resist deformation; influential factors include dehydration and age" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal turgor" EXACT []
is_a: MT:0001191 ! skin condition

[Term]
id: MT:0003656
name: erythrocyte physiology
namespace: Trait.ontology
def: "functional anomaly of the cells in the blood that carry oxygen, red blood cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0001545 ! hematopoietic system physiology

[Term]
id: MT:0003657
name: erythrocyte lysis
namespace: Trait.ontology
def: "increase or decrease in the ability of RBCs to withstand changes in osmolarity" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "erythrocyte fragility" EXACT []
is_a: MT:0003656 ! erythrocyte physiology

[Term]
id: MT:0003658
name: capillary integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness minute blood vessels that connect arterioles and venules" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0000088 ! blood vessel integrity
relationship: part_of MT:0000087 ! capillary morphology

[Term]
id: MT:0003659
name: lymph circulation
namespace: Trait.ontology
def: "flow of the lymph from the tissues into the veins of the circulatory system" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
is_a: MT:0001790 ! immune system physiology
is_a: MT:0002128 ! blood circulation

[Term]
id: MT:0003661
name: locus ceruleus morphology
namespace: Trait.ontology
def: "anomaly in a dense cluster of neurons within the dorsorostral pons; it is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic" [J:96328, Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
is_a: MT:0000848 ! pons morphology

[Term]
id: MT:0003662
name: epiphyseal plate proliferative zone morphology
namespace: Trait.ontology
def: "germinal layer of the epiphyseal plate where cells are actively dividing as well as producing extracellular matrix" [J:96254, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000164 ! cartilage development
is_a: MT:0003055 ! epiphyseal plate morphology

[Term]
id: MT:0003663
name: thermosensation
namespace: Trait.ontology
synonym: "abnormal thermal preference" EXACT []
synonym: "impaired thermosensation" EXACT []
is_a: MT:0002067 ! sensory capabilities/reflexes/nociception

[Term]
id: MT:0003664
name: ocular pterygium
namespace: Trait.ontology
def: "mass of tissue arising from the conjunctiva of the inner corner of the eye that obstructs vision by growing over the cornea" [J:96018, monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0001310 ! conjunctiva morphology

[Term]
id: MT:0003665
name: endophthalmitis
namespace: Trait.ontology
def: "inflammation of the internal structures of the tissues in the eyeball" [J:96018, monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0001851 ! eye inflammation
is_a: MT:0005195 ! posterior eye segment morphology

[Term]
id: MT:0003666
name: sperm capacitation
namespace: Trait.ontology
def: "anomaly in the change undergone by spermatozoa in the female genital tract that enables them to penetrate and fertilize an egg" [J:96669, monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0003698 ! male reproductive system physiology

[Term]
id: MT:0003667
name: hemangiosarcoma
namespace: Trait.ontology
def: "a malignant tumor characterized by rapidly proliferating, extensively infiltrating, anaplastic cells derived from blood vessels and appear as irregular blood-filled or lumpy sacs that are typically filled with blood; rupture of the tumor can cause rapid death from bleeding" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:53511, MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "angiosarcoma" EXACT []
is_a: MT:0002032 ! sarcoma

[Term]
id: MT:0003668
name: periodontal ligament morphology
namespace: Trait.ontology
def: "any structural anomaly in the fibrous connective tissue that surrounds the root of a tooth, separating it from and attaching it to the alveolar bone; normally extends from the base of the gingival mucosa to the fundus of the bony socket, and its main function is to hold the tooth in its socket" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:66512]
synonym: "abnormal periodontium" EXACT []
is_a: MT:0002100 ! tooth morphology

[Term]
id: MT:0003670
name: glomerular capsule size
namespace: Trait.ontology
def: "an expansion in volume of the expanded beginning of a nephron that contains the glomerulus" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:91499]
synonym: "dilated Bowman's capsule" EXACT []
is_a: MT:0002828 ! glomerular capsule morphology

[Term]
id: MT:0003671
name: eyelid opening
namespace: Trait.ontology
def: "partially or completely shut eyes " [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001340 ! eyelid morphology

[Term]
id: MT:0003672
name: ureter development
namespace: Trait.ontology
def: "anomalous differentiation of the tube that conducts the urine from the renal pelvis to the bladder" [J:96485, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000534 ! ureter morphology
is_a: MT:0003942 ! urinary system development

[Term]
id: MT:0003673
name: inguinal canal morphology
namespace: Trait.ontology
def: "the passage in the lower abdominal wall through which the spermatic cord in the male or the round ligament in the female, nerves and vessels pass from the pelvic cavity to the scrotum or labia majora, respectively " [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002160 ! reproductive system morphology

[Term]
id: MT:0003674
name: oxidative stress
namespace: Trait.ontology
def: "condition characterized by an accumulation of free radical groups in the body, which creates a potentially unstable and damaging cellular environment linked to tissue damage, accelerated aging, and degenerative disease; can result from many factors, including exposure to alcohol, medications, poor nutrition, trauma, cold or toxins; may be indicated by low antioxidant levels measured in blood plasma" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0003186 ! redox activity

[Term]
id: MT:0003675
name: kidney cysts
namespace: Trait.ontology
alt_id: MT:0005347
def: "abnormal membranous sacs in any portion of the pair of organs responsible for urine secretion" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "cystic kidney" EXACT []
synonym: "renal cysts" EXACT []
is_a: MT:0002135 ! kidney morphology

[Term]
id: MT:0003677
name: ear lobe morphology
namespace: Trait.ontology
def: "form or structure of the soft tissue at the base of the outer ear; consists of fat and fibrous tissue not reinforced by the auricular cartilage " [ncbi:Matthew Mailman_NCBI request, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002177 ! outer ear morphology

[Term]
id: MT:0003679
name: ear lobe size
namespace: Trait.ontology
def: "length, width, thickness, or area of the ear lobes" [ncbi:Matthew Mailman_NCBI request]
synonym: "hypoplastic ear lobes" EXACT []
is_a: MT:0003677 ! ear lobe morphology

[Term]
id: MT:0003684
name: inferior olivary complex morphology
namespace: Trait.ontology
def: "any structural abnormality in the capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids; neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex and have been implicated in various functions, such as learning and timing of movements" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal inferior olivary nucleus" EXACT []
synonym: "abnormal inferior olive" EXACT []
synonym: "abnormal oliva" EXACT []
is_a: MT:0000846 ! medulla oblongata

[Term]
id: MT:0003685
name: cardiac ganglion morphology
namespace: Trait.ontology
def: "any anomaly of the parasympathetic ganglia of the cardiac plexus between the arch of the aorta and the bifurcation of the pulmonary artery " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal cardiac ganglia" EXACT []
synonym: "abnormal Wrisberg ganglion" EXACT []
is_a: MT:0001034 ! parasympathetic ganglia morphology

[Term]
id: MT:0003686
name: eye muscle morphology
namespace: Trait.ontology
def: "malformation of the muscles of the eye" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002092 ! eye morphology
is_a: MT:0002108 ! muscle morphology

[Term]
id: MT:0003687
name: intraocular muscle morphology
namespace: Trait.ontology
def: "malformation of the smooth muscles within the eye" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000767 ! smooth muscle morphology
is_a: MT:0003686 ! eye muscle morphology

[Term]
id: MT:0003688
name: eye muscle strength
namespace: Trait.ontology
is_a: MT:0000747 ! muscle strength
is_a: MT:0001389 ! eye movements

[Term]
id: MT:0003689
name: ability to move the eye muscles
namespace: Trait.ontology
is_a: MT:0000753 ! ability to move
is_a: MT:0001389 ! eye movements
is_a: MT:0002106 ! muscle physiology

[Term]
id: MT:0003690
name: glial cell physiology
namespace: Trait.ontology
def: "anomalous function of non-neuronal cells of the central nervous system that form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal glial cell function" EXACT []
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0003691
name: microglial cell physiology
namespace: Trait.ontology
def: "anomalous activity of the small neuroglial cells, possibly of mesodermal origin, which may become phagocytic, in areas of neural damage or inflammation" [hdene:Howard Dene_Mouse Genome Informatics Curator]
is_a: MT:0003690 ! glial cell physiology

[Term]
id: MT:0003692
name: xanthoma
namespace: Trait.ontology
def: "a deposit of cholesterol rich material in a tissue, most often in the skin but also seen in tendons and in the brain" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002118 ! lipid homeostasis

[Term]
id: MT:0003693
name: embryo hatching
namespace: Trait.ontology
def: "anomalies in the ability of the embryo to break out of the zona pellucida, the thick solid transparent outer membrane that surrounds the developing ovum and embryo prior to implantation, may be seen in vivo or in cultured embryos" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001672 ! embryogenesis/ development

[Term]
id: MT:0003696
name: zona pellucida morphology
namespace: Trait.ontology
def: "anomaly or absence of the thick solid transparent outer membrane that surrounds the developing ovum and embryo prior to implantation" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001131 ! ovarian follicle morphology

[Term]
id: MT:0003698
name: male reproductive system physiology
namespace: Trait.ontology
def: "anomaly in the function of the male organs associated with producing offspring " [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001919 ! reproductive system physiology

[Term]
id: MT:0003699
name: female reproductive system physiology
namespace: Trait.ontology
def: "anomaly in the function of the female organs associated with producing offspring" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_pig
is_a: MT:0001919 ! reproductive system physiology

[Term]
id: MT:0003700
name: oviduct transport
namespace: Trait.ontology
def: "increased or decreased rate of passage of embryos or oocytes from the ovary to the uterus" [J:97633, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0004015 ! oviduct environment

[Term]
id: MT:0003701
name: level of sister chromatid exchange
namespace: Trait.ontology
def: "increased number of crossovers between sister chromatids during meiosis resulting in increased numbers of reciprocal exchanges of DNA between the two chromosomes" [hdene:Howard Dene_Mouse Genome Informatics Curator, J:97667]
is_a: MT:0003702 ! chromosome morphology

[Term]
id: MT:0003702
name: chromosome morphology
namespace: Trait.ontology
def: "anomalies in the structure of the compact, intertwined molecules of DNA found in the nucleus which carry genetic information " [hdene:Howard Dene_Mouse Genome Informatics Curator]
is_a: MT:0003111 ! nucleus morphology

[Term]
id: MT:0003703
name: vestibulocochlear ganglion morphology
namespace: Trait.ontology
alt_id: MT:0001090
def: "malformed group of neuron cell bodies associated with the eighth cranial nerve during embryogenesis; splits in later development to form the cochlear and vestibular ganglia" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal spiral ganglion" EXACT []
synonym: "abnormal vestibular cochlear ganglion" EXACT []
synonym: "abnormal vestibular cochlear ganglion morphology" EXACT []
is_a: MT:0003861 ! nervous system development

[Term]
id: MT:0003704
name: hair follicle development
namespace: Trait.ontology
def: "anomalous development of the epidermis from which the hair shaft develops" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0000367 ! coat/ hair morphology

[Term]
id: MT:0003705
name: hypodermis morphology
namespace: Trait.ontology
def: "malformed or atypical condition of the innermost and thickest layer of the skin composed of loose connective tissue containing adipocytes" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0002060 ! skin morphology

[Term]
id: MT:0003706
name: nucleus count
namespace: Trait.ontology
def: "absent or greater than one nuclei present per cell body when one is expected; often due to failed cytokinesis or events leading to apoptosis" [pg:Philip Groth submission]
is_a: MT:0000358 ! cell content/ morphology

[Term]
id: MT:0003710
name: vascularization
namespace: Trait.ontology
def: "new blood vessel development" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0000249 ! blood vessel physiology

[Term]
id: MT:0003713
name: ear rotation
namespace: Trait.ontology
def: "orientation of the outer ears in relation to the anterior-posterior body axis, does not refer to the point of emergence on the head" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0002177 ! outer ear morphology

[Term]
id: MT:0003714
name: absence of platelets
namespace: Trait.ontology
def: "lack of non-nucleated cells found in the blood and involved in blood coagulation " [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0003179 ! platelet count

[Term]
id: MT:0003717
name: skin color
namespace: Trait.ontology
def: "an unnatural paleness to the skin, generally attributable to anemia" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "pale skin" EXACT []
synonym: "pallid" EXACT []
is_a: MT:0001191 ! skin condition

[Term]
id: MT:0003718
name: maternal effect
namespace: Trait.ontology
def: "expression of a phenotypic trait in an female animal's offspring that is dependent on the maternal genotype" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0005389 ! reproductive system trait

[Term]
id: MT:0003719
name: pericyte integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the connective tissue cells that occurs around capillaries or other small blood vessels" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
relationship: part_of MT:0000088 ! blood vessel integrity

[Term]
id: MT:0003720
name: neural tube closure
namespace: Trait.ontology
def: "abnormal invagination and fusion of the neuroepithelial layer in early development" [J:99099, monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0002151 ! neural tube morphology/development

[Term]
id: MT:0003721
name: tumor growth/size
namespace: Trait.ontology
def: "greater than expected development of tumorous growth when compared to controls" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003448 ! tumor morphology

[Term]
id: MT:0003722
name: ureter number
namespace: Trait.ontology
def: "missing the tube that conducts the urine from the renal pelvis to the bladder" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000534 ! ureter morphology

[Term]
id: MT:0003723
name: long bone morphology
namespace: Trait.ontology
def: "malformation of any of the several elongated bones of the extremities" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
subset: slim_chkn
subset: slim_pig
is_a: MT:0002115 ! skeleton extremities morphology

[Term]
id: MT:0003724
name: susceptibility to induced arthritis
namespace: Trait.ontology
def: "more likely to be stricken with changes in the synovial membranes and thickening of articular structures, widespread degeneration of the collagen fibers in connective tissues, and by atrophy and rarefaction of bony structures that are induced by inflammatory responses caused by chemical or mechanical agents" [acv:Alicia Valenzuela_Genetic Resources Curator]
is_a: MT:0002993 ! arthritis

[Term]
id: MT:0003726
name: autoantibody level
namespace: Trait.ontology
def: "reduced level of antibodies to self-antigens present in the sera" [acv:Alicia Valenzuela_Genetic Resources Curator, csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001844 ! autoimmune response

[Term]
id: MT:0003727
name: retinal layer morphology
namespace: Trait.ontology
def: "malformation in any of the layers that make up the retina" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001325 ! retina morphology

[Term]
id: MT:0003728
name: photoreceptor layer
namespace: Trait.ontology
def: "malformation/anomalous structure of the photoreceptor layer" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0006069 ! retinal neuronal layer morphology

[Term]
id: MT:0003729
name: photoreceptor outer segments
namespace: Trait.ontology
def: "malformation/anomalous structure of the photoreceptor layer which contains stacks of membranous discs that are rich in the visual pigment rhodopsin " [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0003728 ! photoreceptor layer

[Term]
id: MT:0003730
name: photoreceptor inner segments
namespace: Trait.ontology
def: "malformation/anomalous structure of the photoreceptor layer which contains the machinery of the cell (mitochondria, golgi, endoplasmic reticulum, etc)" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0003728 ! photoreceptor layer

[Term]
id: MT:0003731
name: outer nuclear layer morphology
namespace: Trait.ontology
def: "malformation/anomalous structure of the retinal layer that contains the nuclei and cell bodies of rods and cones" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0006069 ! retinal neuronal layer morphology

[Term]
id: MT:0003732
name: outer plexiform layer morphology
namespace: Trait.ontology
def: "malformation/anomalous structure of the retinal layer that is the site of synapses between the rods and cones (axons) and the horizontal and bipolar cells (dendrites)" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0006069 ! retinal neuronal layer morphology

[Term]
id: MT:0003733
name: inner nuclear layer morphology
namespace: Trait.ontology
def: "malformation/anomalous structure of the retinal layer which contains the cell bodies of bipolar, horizontal, and amacrine cells" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0006069 ! retinal neuronal layer morphology

[Term]
id: MT:0003734
name: inner plexiform layer morphology
namespace: Trait.ontology
def: "malformation/anomalous structure of the retinal cell layer where bipolar and amacrine cell axons synapse with ganglion cell dendrites" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0006069 ! retinal neuronal layer morphology

[Term]
id: MT:0003737
name: outer ear cartilage morphology
namespace: Trait.ontology
def: "structure or form of the cartilage of the outer ear" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0002177 ! outer ear morphology

[Term]
id: MT:0003739
name: middle ear ossicle size
namespace: Trait.ontology
def: "length, width, or volume of the three small bones of the middle ear" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0005105 ! middle ear ossicle morphology

[Term]
id: MT:0003743
name: facial morphology
namespace: Trait.ontology
def: "anomalous structure or development of the face" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000432 ! head morphology

[Term]
id: MT:0003744
name: orofacial morphology
namespace: Trait.ontology
def: "anomalous structure or development of the oral cavities of the face" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003743 ! facial morphology

[Term]
id: MT:0003745
name: mucosal lining of the mouth
namespace: Trait.ontology
def: "anomalous structure or development of the mucus -secreting tissue that lines the oral cavity" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000452 ! mouth morphology

[Term]
id: MT:0003746
name: stomatitis
namespace: Trait.ontology
def: "inflammation of the mucous lining of the mouth" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001846 ! tissue specific inflammatory response
is_a: MT:0003745 ! mucosal lining of the mouth

[Term]
id: MT:0003747
name: mouth mucosal ulceration
namespace: Trait.ontology
def: "lesions through the mucous membrane of the mouth" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003745 ! mucosal lining of the mouth

[Term]
id: MT:0003748
name: oral mucosa hemangioma
namespace: Trait.ontology
def: "proliferation of blood vessels in the oral mucosa that leads to a mass that resembles a benign neoplasm" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0002947 ! hemangioma
is_a: MT:0003750 ! mouth tumor

[Term]
id: MT:0003749
name: down-turned corners of mouth
namespace: Trait.ontology
def: "the lateral points of the oral cavity opening appear in a lower position that the rest of the lips" [ncbi:Matthew Mailman_NCBI request]
synonym: "down slanted corners of mouth" EXACT []
synonym: "down turned corners of mouth" EXACT []
synonym: "down-slanted corners of mouth" EXACT []
is_a: MT:0000452 ! mouth morphology

[Term]
id: MT:0003750
name: mouth tumor
namespace: Trait.ontology
def: "presence of abnormal rapidly proliferating cells in the mouth, usually in the form of a distinct mass" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0003751
name: oral leukoplakia
namespace: Trait.ontology
def: "white precancerous lesions of the mucous membranes of the oral cavity" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003750 ! mouth tumor

[Term]
id: MT:0003752
name: oral papilloma
namespace: Trait.ontology
def: "benign epithelial tumor of the oral cavity" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0002014 ! papilloma
is_a: MT:0003750 ! mouth tumor

[Term]
id: MT:0003753
name: lip papilloma
namespace: Trait.ontology
def: "benign epithelial tumor of the lip of the oral cavity" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003752 ! oral papilloma
is_a: MT:0003780 ! lip tumor

[Term]
id: MT:0003754
name: gingival papilloma
namespace: Trait.ontology
def: "benign epithelial tumor of the oral gum tissue" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003752 ! oral papilloma

[Term]
id: MT:0003755
name: palate
namespace: Trait.ontology
def: "anomaly in the roof of the mouth in vertebrates formed anteriorly by a bony projection of the upper jaw (hard palate) and posteriorly by the fold of connective tissue (soft palate) " [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0000452 ! mouth morphology

[Term]
id: MT:0003756
name: hard palate
namespace: Trait.ontology
def: "abnormality in the anterior part of the palate that is supported by and includes the palatal extensions of the maxillary and palatine bones " [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003755 ! palate

[Term]
id: MT:0003759
name: palate width
namespace: Trait.ontology
def: "abnormally wide shape to the roof of the oral cavity" [ncbi:Matthew Mailman_NCBI request]
synonym: "wide palate" EXACT []
is_a: MT:0003755 ! palate

[Term]
id: MT:0003760
name: palate length
namespace: Trait.ontology
def: "length to the roof of the oral cavity" [ncbi:Matthew Mailman_NCBI request, smb:MGI_curator]
is_a: MT:0003755 ! palate

[Term]
id: MT:0003761
name: arched palate
namespace: Trait.ontology
def: "concave shape to the roof of the oral cavity" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003755 ! palate

[Term]
id: MT:0003762
name: immune organ physiology
namespace: Trait.ontology
def: "abnormal function of the organs of the immune system" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001790 ! immune system physiology

[Term]
id: MT:0003763
name: thymus physiology
namespace: Trait.ontology
def: "anomalous function of the primary lymphoid organ that is required for immune system development" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001545 ! hematopoietic system physiology
is_a: MT:0003762 ! immune organ physiology

[Term]
id: MT:0003764
name: palatal depth
namespace: Trait.ontology
def: "any change in the average distance of the deepest point in the midline of the palate relative to the midline point on the anterior crest of the alveolar gum pad ridge" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003755 ! palate

[Term]
id: MT:0003767
name: palatial inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins and leukocytes in the palate" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001846 ! tissue specific inflammatory response
is_a: MT:0003755 ! palate

[Term]
id: MT:0003768
name: palatal telangiectases*
namespace: Trait.ontology
def: "vascular lesion formed by dilation of a group of small blood vessels in the palate" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003755 ! palate

[Term]
id: MT:0003769
name: lip morphology
namespace: Trait.ontology
def: "anomalous structure or development of the fleshy margins of the mouth" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003744 ! orofacial morphology

[Term]
id: MT:0003770
name: lip ulceration
namespace: Trait.ontology
def: "lesions through the mucous membrane of the inner surface of the lip" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003769 ! lip morphology

[Term]
id: MT:0003771
name: lip shape
namespace: Trait.ontology
def: "changes in the characteristic contours of the fleshy margins of the mouth" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003769 ! lip morphology

[Term]
id: MT:0003772
name: lip pits
namespace: Trait.ontology
def: "a hollow or depression in the fleshy margins of the mouth" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003769 ! lip morphology

[Term]
id: MT:0003773
name: everted lip
namespace: Trait.ontology
def: "an outward turning of the inner surface of the lip" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003769 ! lip morphology

[Term]
id: MT:0003774
name: fleshy lip
namespace: Trait.ontology
def: "lips having an abundance and often an excess of soft tissue" [ncbi:Matthew Mailman_NCBI request]
synonym: "full lip" EXACT []
synonym: "thick lip" EXACT []
is_a: MT:0003769 ! lip morphology

[Term]
id: MT:0003777
name: lip inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins and leukocytes in the lips" [MeSH:National Library of Medicine_Medical Subject Headings, ncbi:Matthew Mailman_NCBI request]
is_a: MT:0001846 ! tissue specific inflammatory response
is_a: MT:0003769 ! lip morphology

[Term]
id: MT:0003778
name: lip telangiectases*
namespace: Trait.ontology
def: "vascular lesion formed by dilation of a group of small blood vessels in the lip" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003769 ! lip morphology

[Term]
id: MT:0003779
name: lip cysts
namespace: Trait.ontology
def: "fluid-filled membranous sacs present in the lips" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003769 ! lip morphology

[Term]
id: MT:0003780
name: lip tumor
namespace: Trait.ontology
def: "presence of abnormal rapidly proliferating cells in the lip, usually in the form of a distinct mass" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0003781
name: lip neuroma
namespace: Trait.ontology
def: "tumor derived from nerve cells or fibers residing in the lip" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003780 ! lip tumor

[Term]
id: MT:0003783
name: tented upper lip
namespace: Trait.ontology
def: "an upper lip having an inverted V- shape " [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003769 ! lip morphology

[Term]
id: MT:0003784
name: lip vermillion border
namespace: Trait.ontology
def: "reduced thickness of the line between the lip and the facial skin around the mouth " [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003769 ! lip morphology

[Term]
id: MT:0003785
name: lip mucosal nodules
namespace: Trait.ontology
def: "small mass of tissue or aggregation of cells in the mucosal tissue of the inner lip" [ncbi:Matthew Mailman_NCBI request]
is_a: MT:0003769 ! lip morphology

[Term]
id: MT:0003786
name: onset of aging
namespace: Trait.ontology
def: "earlier than normal occurrence of the normal signs of aging" [J:97764, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005372 ! life span/aging trait

[Term]
id: MT:0003788
name: interferon physiology
namespace: Trait.ontology
def: "impairment or increase of the cellular release of any of the cytokines produced by T cells, fibroblasts and other cells in response to a challenge by a foreign agents such as viruses, bacteria, parasites and tumor cells " [hdene:Howard Dene_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005049 ! cytokine physiology

[Term]
id: MT:0003789
name: osteosarcoma
namespace: Trait.ontology
def: "malignant neoplasm derived from bone" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002032 ! sarcoma

[Term]
id: MT:0003790
name: absent CD4+8- cells
namespace: Trait.ontology
def: "lack of the set of single-positive T cells that express CD4 on their surface" [acv:Alicia Valenzuela_Genetic Resources Curator, csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002432 ! CD4+ T cell morphology/development

[Term]
id: MT:0003791
name: minor salivary gland morphology
namespace: Trait.ontology
def: "any structural malformations of the smaller, largely mucus-secreting, exocrine glands of the oral cavity, consisting of the labial, buccal, molar, lingual, and palatine glands" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000613 ! salivary gland morphology

[Term]
id: MT:0003792
name: major salivary gland morphology
namespace: Trait.ontology
def: "any structural malformations of the three largest glands of the oral cavity that secrete most of the saliva, including the parotid, submandibular, and sublingual glands " [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000613 ! salivary gland morphology

[Term]
id: MT:0003793
name: submandibular gland morphology
namespace: Trait.ontology
def: "any structural malformation of either of the large major salivary glands situated beneath the mandible" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0003792 ! major salivary gland morphology

[Term]
id: MT:0003794
name: onset of somite formation
namespace: Trait.ontology
def: "late onset of the induction and/or differentiation of the somites" [J:99723, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001688 ! somite development

[Term]
id: MT:0003795
name: bone structure
namespace: Trait.ontology
def: "anomaly in the composite material or the layered arrangement of the bony endoskeleton of the body" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_pig
is_a: MT:0005508 ! skeleton morphology

[Term]
id: MT:0003796
name: cortical bone morphology
namespace: Trait.ontology
def: "structural anomaly of the superficial thin layer of compact bone" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003797 ! compact bone morphology

[Term]
id: MT:0003797
name: compact bone morphology
namespace: Trait.ontology
def: "structural anomaly of the outer layers of solid, hard bone that covers spongy bone; consists of parallel osteons containing mineral deposits and interstitial lamellae" [hdene:Howard Dene_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal dense bone" EXACT []
synonym: "abnormal lamellar bone" EXACT []
is_a: MT:0003795 ! bone structure

[Term]
id: MT:0003798
name: Harderian gland pigmentation
namespace: Trait.ontology
def: "anomalous coloring of the sebaceous gland located behind the eyeball in the orbit that excretes fluid that facilitates movement of the third eyelid" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0001186 ! pigmentation trait

[Term]
id: MT:0003799
name: macrophage migration
namespace: Trait.ontology
def: "defect in the ability of macrophages to move up a chemotactic gradient" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005495 ! macrophage recruitment

[Term]
id: MT:0003800
name: monodactyly
namespace: Trait.ontology
def: "having only one toe or digit on each extremity" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
synonym: "monodactylous" EXACT []
is_a: MT:0002110 ! digit morphology

[Term]
id: MT:0003801
name: histocompatibility locus
namespace: Trait.ontology
def: "deviation from the parental type of histocompatibility" [mberry:Melissa Berry_Genetics Resources Curator]
synonym: "altered histocompatibility locus" EXACT []
is_a: MT:0001790 ! immune system physiology

[Term]
id: MT:0003802
name: class I histocompatibility locus
namespace: Trait.ontology
def: "deviation from the parental type of class I histocompatibility" [mberry:Melissa Berry_Genetics Resources Curator]
is_a: MT:0003801 ! histocompatibility locus

[Term]
id: MT:0003803
name: class II histocompatibility locus
namespace: Trait.ontology
def: "deviation from the parental type of class II histocompatibility" [mberry:Melissa Berry_Genetics Resources Curator]
is_a: MT:0003801 ! histocompatibility locus

[Term]
id: MT:0003804
name: minor histocompatibility locus
namespace: Trait.ontology
def: "deviation from the parental type of minor histocompatibility" [mberry:Melissa Berry_Genetics Resources Curator]
is_a: MT:0003801 ! histocompatibility locus

[Term]
id: MT:0003805
name: histocompatibility-related locus
namespace: Trait.ontology
def: "deviation from the parental type of a histocompatibility-related locus" [mberry:Melissa Berry_Genetics Resources Curator]
is_a: MT:0003801 ! histocompatibility locus

[Term]
id: MT:0003806
name: nucleotide metabolism
namespace: Trait.ontology
def: "impaired regulation of nucleotide levels in either production or breakdown of these structural components of nucleic acids" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002121 ! metabolism

[Term]
id: MT:0003807
name: camptodactyly
namespace: Trait.ontology
def: "permanent flexion of one or more digits; contractures may also be seen in the wrists and at the elbows" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002110 ! digit morphology

[Term]
id: MT:0003809
name: hair shaft morphology
namespace: Trait.ontology
alt_id: MT:0002854
def: "irregular or unusual structure of the cuticle, and/or cortex and/or medulla of a hair" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
synonym: "abnormal hair shaft" EXACT []
is_a: MT:0000367 ! coat/ hair morphology

[Term]
id: MT:0003810
name: hair cuticle morphology
namespace: Trait.ontology
def: "anomalies in the thin, smooth and glossy outer protective cell layer of hair shaft" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0003809 ! hair shaft morphology

[Term]
id: MT:0003811
name: hair cortex morphology
namespace: Trait.ontology
def: "anomalies in the spindle shaped cells of the hair shaft that contains keratin fibrils and matrix" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0003809 ! hair shaft morphology

[Term]
id: MT:0003812
name: hair medulla morphology
namespace: Trait.ontology
def: "anomalies of hair medullary cell formation and arrangement of the innermost core of the hair shaft " [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0003809 ! hair shaft morphology

[Term]
id: MT:0003813
name: dermal papilla morphology
namespace: Trait.ontology
def: "abnormalities in this specialized group of mesenchymal cells necessary for initiation of follicle development" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0002076 ! hair follicle structure/orientation

[Term]
id: MT:0003815
name: hair number
namespace: Trait.ontology
def: "total number of hairs" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
subset: slim_pig
synonym: "amount of hair" RELATED []
is_a: MT:0001510 ! coat appearance
is_a: MT:0002073 ! hair growth

[Term]
id: MT:0003816
name: pituitary gland development
namespace: Trait.ontology
def: "malformation or incomplete differentiation of the compound gland suspended from the base of the hypothalamus, which secretes somatotropins, prolactin, TSH (thyroid-stimulating hormone), gonadotropins, adrenal corticotropin" [J:51160, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000633 ! pituitary gland morphology

[Term]
id: MT:0003817
name: Rathke's pouch morphology
namespace: Trait.ontology
def: "malformation or incomplete differentiation of a pouch of ectoderm that grows out from the upper surface of the embryonic stomodeum and gives rise to the anterior and intermediate lobes of the pituitary gland" [J:51160, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal Rathke's pocket" EXACT []
is_a: MT:0003816 ! pituitary gland development

[Term]
id: MT:0003818
name: eye muscle development
namespace: Trait.ontology
def: "malformation or arrest of differentiation of the muscles of the eye" [J:51160, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000733 ! muscle development
is_a: MT:0001286 ! eye development

[Term]
id: MT:0003821
name: left ventricle diastolic pressure
namespace: Trait.ontology
def: "decrease in the pressure in the left ventricle between heart beats when the heart is relaxed" [RGD:cur "Rat Genome Database submission"]
is_a: MT:0006263 ! diastolic blood pressure

[Term]
id: MT:0003822
name: left ventricle systolic pressure
namespace: Trait.ontology
def: "pressure in the left ventricle as the heart contracts and pumps blood into the arteries" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0006264 ! systolic blood pressure

[Term]
id: MT:0003824
name: left ventricular developed pressure
namespace: Trait.ontology
def: "difference between left ventricular systolic and diastolic pressures" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0000230 ! blood pressure

[Term]
id: MT:0003825
name: pillar cell morphology
namespace: Trait.ontology
def: "form, structure or number of the supporting cells that form the inner and outer walls of the tunnel in the organ of Corti " [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0004300 ! organ of Corti supporting cell morphology

[Term]
id: MT:0003826
name: Mullerian duct morphology
namespace: Trait.ontology
def: "malformation of the transient embryonic tubes that empty into the cloaca and in the female develop into the oviducts, uterus, and vagina" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal Muller duct morphology" EXACT []
is_a: MT:0003936 ! reproductive system development

[Term]
id: MT:0003827
name: Wolffian duct morphology
namespace: Trait.ontology
def: "malformation of the transient embryonic tubes that empty into the cloaca and degenerate in the male " [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0003936 ! reproductive system development

[Term]
id: MT:0003828
name: pulmonary edema
namespace: Trait.ontology
def: "an accumulation of an excessive amount of watery fluid in the lung " [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:44108]
is_a: MT:0001785 ! edema
is_a: MT:0002133 ! respiratory system physiology

[Term]
id: MT:0003829
name: febrile response
namespace: Trait.ontology
def: "reduced or absent febrile response to exogenous or endogenous pyrogens" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:70534]
is_a: MT:0001777 ! body temperature regulation

[Term]
id: MT:0003830
name: testis development
namespace: Trait.ontology
def: "abnormal morphogenesis of the male reproductive gland containing the germ cells" [J:100020, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001146 ! testis morphology
is_a: MT:0003936 ! reproductive system development

[Term]
id: MT:0003831
name: prostate tumor
namespace: Trait.ontology
def: "presence of abnormal rapidly proliferating cells in the prostate, usually in the form of a distinct mass" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0003833
name: number of satellite cells
namespace: Trait.ontology
def: "less than the normal number of unfused cells in muscle that play a role in muscle regeneration" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000759 ! skeletal muscle morphology

[Term]
id: MT:0003834
name: adrenergic chromaffin cell morphology
namespace: Trait.ontology
def: "malformation of the cells responsible for epinephrine and norepinephrine secretion" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000639 ! adrenal gland morphology

[Term]
id: MT:0003838
name: milk ejection
namespace: Trait.ontology
def: "impaired milk ejection reflex in response to suckling during lactation" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:36926]
is_a: MT:0001882 ! lactation

[Term]
id: MT:0003839
name: insulin clearance
namespace: Trait.ontology
def: "increase or decrease in the rate at which insulin is removed from the blood stream" [J:99786, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002078 ! glucose homeostasis

[Term]
id: MT:0003840
name: coronal suture morphology
namespace: Trait.ontology
def: "malformation of the articulation between the parietal bones and the frontal bone" [smb:Susan M. Bello_Mouse Genome Informatics Curator, Taber's Cyclopedic Medical Dictionary_19th edition:ISBN N 0-8036-0655-99]
synonym: "abnormal frontoparietal suture morphology" EXACT []
is_a: MT:0002835 ! cranial suture morphology

[Term]
id: MT:0003841
name: lambdoidal suture morphology
namespace: Trait.ontology
def: "malformation of the articulation of the parietal bones and the occipital bone" [smb:Susan M. Bello_Mouse Genome Informatics Curator, Taber's Cyclopedic Medical Dictionary_19th edition:ISBN N 0-8036-0655-99]
synonym: "abnormal occipital suture morphology" EXACT []
synonym: "abnormal occipitoparietal suture morphology" EXACT []
is_a: MT:0002835 ! cranial suture morphology

[Term]
id: MT:0003842
name: metopic suture morphology
namespace: Trait.ontology
def: "malformation of the articulation of the frontal bone from the sagittal suture to the root of the nose" [smb:Susan M. Bello_Mouse Genome Informatics Curator, Taber's Cyclopedic Medical Dictionary_19th edition:ISBN N 0-8036-0655-99]
synonym: "abnormal frontal suture morphology" EXACT []
synonym: "abnormal mediofrontal suture morphology" EXACT []
is_a: MT:0002835 ! cranial suture morphology

[Term]
id: MT:0003843
name: sagittal suture morphology
namespace: Trait.ontology
def: "malformation of the articulation between the parietal bones" [smb:Susan M. Bello_Mouse Genome Informatics Curator, Taber's Cyclopedic Medical Dictionary_19th edition:ISBN N 0-8036-0655-99]
synonym: "abnormal interparietal suture morphology" EXACT []
synonym: "abnormal longitudinal suture morphology" EXACT []
synonym: "abnormal parietal suture morphology" EXACT []
is_a: MT:0002835 ! cranial suture morphology

[Term]
id: MT:0003844
name: squamo-parietal suture morphology
namespace: Trait.ontology
def: "malformation of the articulation of the squamous portion of the temporal bones with the parietal bones" [smb:Susan M. Bello_Mouse Genome Informatics Curator, Taber's Cyclopedic Medical Dictionary_19th edition:ISBN N 0-8036-0655-99]
is_a: MT:0002835 ! cranial suture morphology

[Term]
id: MT:0003845
name: decidualization
namespace: Trait.ontology
def: "disrupted proliferation, differentiation or transformation of endometrial stromal cells into decidual cells in the maternal uterus following embryo implantation" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:43609, J:48920]
synonym: "defective decidualization" EXACT []
is_a: MT:0004014 ! uterine environment

[Term]
id: MT:0003846
name: matted coat
namespace: Trait.ontology
def: "coat hairs sticks together to form clumps and does not lie flat" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0001510 ! coat appearance
is_a: MT:0002074 ! hair texture

[Term]
id: MT:0003847
name: lens bow organization
namespace: Trait.ontology
def: "derangement of the area where the lens epithelium pushes into the lens proper and forms new lens fibers" [brs:Beverly Richards-Smith_Mouse Genome Informatics Curator]
is_a: MT:0001303 ! lens morphology

[Term]
id: MT:0003848
name: brittle hair
namespace: Trait.ontology
def: "hair is susceptible to breakage " [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0002074 ! hair texture

[Term]
id: MT:0003849
name: greasy coat
namespace: Trait.ontology
def: "fur is oily in appearance or texture" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0001510 ! coat appearance

[Term]
id: MT:0003850
name: thymocyte activation/response
namespace: Trait.ontology
def: "anomaly in the process of producing activated thymocytes from naive thymocytes" [mberry:Melissa Berry_Genetics Resources Curator]
is_a: MT:0001819 ! immune cell physiology

[Term]
id: MT:0003851
name: skeletal muscle interstitial fibrosis
namespace: Trait.ontology
def: "formation of fibrous tissue within the interstices of skeletal muscle as a result of repair or a reactive process" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000759 ! skeletal muscle morphology

[Term]
id: MT:0003852
name: skeletal muscle necrosis
namespace: Trait.ontology
def: "pathological cell death in the skeletal muscle, usually due to irreversible damage" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000759 ! skeletal muscle morphology

[Term]
id: MT:0003853
name: skin moisture level
namespace: Trait.ontology
def: "skin characterized by the lack of natural or normal moisture" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0001191 ! skin condition

[Term]
id: MT:0003854
name: forelimb stylopod morphology
namespace: Trait.ontology
def: "malformation of the proximal element of the developing forelimb that will give rise to the humerus" [PMID:12560810]
is_a: MT:0006279 ! limb development

[Term]
id: MT:0003855
name: forelimb zeugopod morphology
namespace: Trait.ontology
def: "malformation of the distal elements of the developing forelimb that will give rise to the radius and ulna" [PMID:12560810]
is_a: MT:0006279 ! limb development

[Term]
id: MT:0003856
name: hindlimb stylopod morphology
namespace: Trait.ontology
def: "malformation of the proximal element of the developing hindlimb that will give rise to the femur" [PMID:12560810]
is_a: MT:0006279 ! limb development

[Term]
id: MT:0003857
name: hindlimb zeugopod morphology
namespace: Trait.ontology
def: "malformation of the distal elements of the developing hindlimb that will give rise to the tibia and fibula" [PMID:12560810]
is_a: MT:0006279 ! limb development

[Term]
id: MT:0003859
name: Harderian gland physiology
namespace: Trait.ontology
def: "anomalous function of the sebaceous gland located behind the eyeball in the orbit that secretes lipids, porphyrins, and indoles such as melatonin" [J:44727, monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0002164 ! gland physiology

[Term]
id: MT:0003860
name: carbon dioxide level
namespace: Trait.ontology
def: "anomalous concentration of CO2 in the blood, alveoli or other tissues resulting in the increased pressure of this component of body gases" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0003948 ! gas homeostasis

[Term]
id: MT:0003861
name: nervous system development
namespace: Trait.ontology
def: "impaired or altered growth of the components of the nervous system" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0003632 ! nervous system morphology

[Term]
id: MT:0003864
name: midbrain development
namespace: Trait.ontology
def: "anomaly in the formation of or the patterning of the part of the brainstem developing from the middle of the three primary cerebral vesicles of the embryo" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000913 ! brain development

[Term]
id: MT:0003865
name: lymph node inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the lymph nodes" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
synonym: "lymphadenitis" EXACT []
is_a: MT:0001846 ! tissue specific inflammatory response

[Term]
id: MT:0003866
name: defecation
namespace: Trait.ontology
def: "anomaly in the production and excretion of feces" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001663 ! digestive system physiology

[Term]
id: MT:0003868
name: feces composition
namespace: Trait.ontology
def: "increase or decrease in the amount of compounds normally found in the feces (fat, protein etc) or presence of material not normally seen in the feces" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001663 ! digestive system physiology

[Term]
id: MT:0003869
name: ectopic cartilage
namespace: Trait.ontology
def: "positional abnormality of cartilage" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000163 ! cartilage morphology

[Term]
id: MT:0003871
name: myelin sheath morphology
namespace: Trait.ontology
def: "malformation of the insulating envelope that surrounds nerve fibers or axons" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005404 ! axon morphology

[Term]
id: MT:0003875
name: hair follicle regression
namespace: Trait.ontology
def: "abnormal length of time for the onset of catagen phase of the cyclic transformation of the hair follicle" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0002076 ! hair follicle structure/orientation

[Term]
id: MT:0003876
name: cerebral function
namespace: Trait.ontology
def: "anomalous activity of the thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon and folds into gyri that is responsible for higher mental functions" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0003877
name: serotonergic neuron morphology
namespace: Trait.ontology
def: "malformation or absence of the neurons that secrete serotonin" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:54240]
is_a: MT:0002882 ! neuron

[Term]
id: MT:0003878
name: ear physiology
namespace: Trait.ontology
def: "functions and processes of the ear" [J:100987, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005377 ! hearing/vestibular/ear trait

[Term]
id: MT:0003879
name: hair cell physiology
namespace: Trait.ontology
def: "function of the sensory epithelial cells of the inner ear" [J:100987, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003878 ! ear physiology
is_a: MT:0005423 ! somatic nervous system physiology

[Term]
id: MT:0003880
name: central pattern generator function
namespace: Trait.ontology
def: "anomalous function of the neural networks that produce rhythmic patterned output without sensory input and underlie rhythmic motor patterns" [J:101019, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0003881
name: nephron morphology
namespace: Trait.ontology
def: "malformation of the filtering unit of the kidney that includes the renal corpuscle, proximal and distal convoluted tubules, and loop of Henle" [J:71588, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002135 ! kidney morphology

[Term]
id: MT:0003882
name: pulse pressure
namespace: Trait.ontology
def: "difference between systolic and diastolic blood pressure" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0000230 ! blood pressure

[Term]
id: MT:0003883
name: stomach size
namespace: Trait.ontology
def: "increased size of the stomach" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0000470 ! stomach morphology

[Term]
id: MT:0003884
name: macrophage count
namespace: Trait.ontology
def: "fewer than the normal numbers of macrophages" [acv:Alicia Valenzuela_Genetic Resources Curator]
is_a: MT:0000223 ! monocyte count
is_a: MT:0002446 ! macrophage morphology/development

[Term]
id: MT:0003885
name: rostro-caudal body axis extension
namespace: Trait.ontology
def: "anomaly in or failure of the long (rostral-caudal) axis of the body to elongate normally once patterning has been established" [brs:Beverly Richards-Smith_Mouse Genome Informatics Curator]
is_a: MT:0002085 ! embryonic tissue morphology

[Term]
id: MT:0003886
name: embryonic epiblast morphology
namespace: Trait.ontology
def: "anomaly in the development/organization of the tissue that gives rise to the ectoderm, endoderm and mesoderm of the embryo proper" [brs:Beverly Richards-Smith_Mouse Genome Informatics Curator]
is_a: MT:0002085 ! embryonic tissue morphology

[Term]
id: MT:0003887
name: hepatocyte apoptosis
namespace: Trait.ontology
def: "increase in the number of hepatocytes undergoing programmed cell death" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000607 ! hepatocyte morphology

[Term]
id: MT:0003890
name: embryonic-extraembryonic boundary morphology
namespace: Trait.ontology
def: "anomaly in the normal development /maintenance of the connection between the embryo proper and extraembryonic tissues" [brs:Beverly Richards-Smith_Mouse Genome Informatics Curator]
is_a: MT:0001672 ! embryogenesis/ development

[Term]
id: MT:0003892
name: gastric gland morphology
namespace: Trait.ontology
def: "anomaly of any of the branched tubular glands in the mucosa of the fundus and body of the stomach that contain parietal cells that secrete hydrochloric acid and zymogenic cells that produce pepsin " [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
synonym: "abnormal fundus gland" EXACT []
synonym: "abnormal gastric follicle" EXACT []
is_a: MT:0005209 ! gastric mucosa morphology

[Term]
id: MT:0003893
name: hepatocyte proliferation
namespace: Trait.ontology
def: "anomalous growth and reproduction of hepatocyte cells of the liver" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000607 ! hepatocyte morphology

[Term]
id: MT:0003894
name: Purkinje cell innervation
namespace: Trait.ontology
def: "malformation or absence of the supply of nerve fibers that connect to the Purkinje cells" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000877 ! Purkinje cell morphology
is_a: MT:0002184 ! innervation

[Term]
id: MT:0003902
name: cell mass
namespace: Trait.ontology
def: "anomaly in the total physical bulk or volume of a cell compared to the normal state" [RGD:Rat Genome Database submission]
is_a: MT:0000358 ! cell content/ morphology

[Term]
id: MT:0003905
name: aorta elastin content
namespace: Trait.ontology
def: "physical amount of elastin in the aorta" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "aortic elastin content" RELATED []
relationship: part_of MT:0007048 ! aorta elastic tissue composition

[Term]
id: MT:0003919
name: lymph node cellularity
namespace: Trait.ontology
def: "anomaly in the cellular make up of the lymph nodes" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002222 ! lymph organ cellularity
is_a: MT:0002339 ! lymph node morphology

[Term]
id: MT:0003920
name: right ventricle morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the right lower chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
subset: slim_chkn
synonym: "right ventricular morphology" RELATED []
xref: MP:0003920
is_a: MT:0005294 ! heart ventricle morphology

[Term]
id: MT:0003921
name: left ventricle morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the left lower chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "left ventricular morphology" RELATED []
xref: MP:0003921
is_a: MT:0005294 ! heart ventricle morphology

[Term]
id: MT:0003922
name: right atrium integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the right upper chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
relationship: part_of MT:0000019 ! right atrium morphology
relationship: part_of MT:0000053 ! heart integrity

[Term]
id: MT:0003923
name: left atrium integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the left upper chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "left atrial integrity" RELATED []
relationship: part_of MT:0000020 ! left atrium morphology
relationship: part_of MT:0000053 ! heart integrity

[Term]
id: MT:0003924
name: herniated diaphragm
namespace: Trait.ontology
def: "protrusion of abdominal contents into the thoracic cavity through the diaphragm" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002279 ! diaphragm morphology

[Term]
id: MT:0003925
name: cellular glucose import
namespace: Trait.ontology
def: "anomaly in the ability of a cell to take in glucose from the environment" [RGD:Rat Genome Database submission]
is_a: MT:0005621 ! cell physiology

[Term]
id: MT:0003929
name: heart rate regularity
namespace: Trait.ontology
def: "consistency of beat-to-beat intervals of the heart" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "heart rate variablility" RELATED []
is_a: MT:0001629 ! heart rate

[Term]
id: MT:0003930
name: tooth hard tissue morphology
namespace: Trait.ontology
def: "defects in the hard portion of the tooth surrounding the pulp, including the dentin, enamel and the cementum on the root" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002100 ! tooth morphology

[Term]
id: MT:0003932
name: molar crown morphology
namespace: Trait.ontology
def: "defects in the upper part of the molar, which is normally covered with enamel " [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002689 ! molar morphology

[Term]
id: MT:0003933
name: cementum morphology
namespace: Trait.ontology
def: "defects in the bonelike rigid connective tissue covering the root of a tooth" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0003930 ! tooth hard tissue morphology

[Term]
id: MT:0003934
name: pancreas development
namespace: Trait.ontology
def: "anomaly in the formation of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001944 ! pancreas morphology
is_a: MT:0003119 ! digestive system development

[Term]
id: MT:0003935
name: craniofacial development
namespace: Trait.ontology
def: "anomaly in the process of forming the face and/or cranium" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000428 ! craniofacial morphology

[Term]
id: MT:0003936
name: reproductive system development
namespace: Trait.ontology
def: "developmental anomaly of any of the organs involved in the reproductive system" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002160 ! reproductive system morphology

[Term]
id: MT:0003937
name: limbs/digits/tail development
namespace: Trait.ontology
def: "anomaly of the formation of the digits, autopod, limbs, or tail" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000545 ! limbs/digits/tail morphology

[Term]
id: MT:0003938
name: ear development
namespace: Trait.ontology
def: "development of any of the structures involved in the ear or vestibular system" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002102 ! ear morphology

[Term]
id: MT:0003939
name: myotome morphology
namespace: Trait.ontology
def: "structural anomaly in the mesoderm that is derived from the somite that is fated to become the musculature" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000733 ! muscle development

[Term]
id: MT:0003940
name: dermatome morphology
namespace: Trait.ontology
def: "anomaly in the mesoderm that is derived from the somite that is fated to become the dermis" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0003941 ! skin development

[Term]
id: MT:0003941
name: skin development
namespace: Trait.ontology
def: "anomaly in the formation of the membranous protective covering of the body" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002096 ! skin condition/ morphology

[Term]
id: MT:0003942
name: urinary system development
namespace: Trait.ontology
is_a: MT:0000516 ! urinary system morphology

[Term]
id: MT:0003943
name: liver/biliary system development
namespace: Trait.ontology
def: "developmental anomaly of any of the tissues of the liver or biliary system" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002138 ! liver/biliary system morphology

[Term]
id: MT:0003944
name: T cell subpopulation ratio
namespace: Trait.ontology
def: "deviation from the standard ratios of T cell subpopulations (e.g. double positive to single positive ratio) compared to control samples" [mberry:Melissa Berry_Genetics Resources Curator]
is_a: MT:0000717 ! lymphocyte number

[Term]
id: MT:0003945
name: lymphocyte physiology
namespace: Trait.ontology
def: "abnormal function of any of the white blood cells that includes B cells, T cells, and NK cells" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
subset: slim_pig
is_a: MT:0002442 ! leukocyte physiology

[Term]
id: MT:0003946
name: renal necrosis
namespace: Trait.ontology
def: "pathological cell death in the kidney, usually due to irreversible damage" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "kidney necrosis" EXACT []
is_a: MT:0002135 ! kidney morphology

[Term]
id: MT:0003947
name: cholesterol level
namespace: Trait.ontology
def: "anomaly in the concentration in the body of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
subset: slim_pig
is_a: MT:0001547 ! lipid level
is_a: MT:0005278 ! cholesterol homeostasis

[Term]
id: MT:0003948
name: gas homeostasis
namespace: Trait.ontology
def: "anomaly in the state of equilibrium in the body of gaseous elements in animal tissues or blood" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001764 ! homeostasis

[Term]
id: MT:0003949
name: circulating lipid level
namespace: Trait.ontology
def: "anomalous concentrations of fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water) in the blood" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
is_a: MT:0000179 ! blood chemistry
is_a: MT:0001547 ! lipid level

[Term]
id: MT:0003950
name: plasma membrane morphology
namespace: Trait.ontology
def: "anomalous structure of the semi-permeable membrane that encloses the cytoplasm of a cell" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
synonym: "abnormal cell membrane morphology" EXACT []
is_a: MT:0000358 ! cell content/ morphology

[Term]
id: MT:0003951
name: copper homeostasis
namespace: Trait.ontology
def: "anomaly in the state of equilibrium in the body with respect to this metallic element that normally occurs in a number of proteins including amine oxidases and chaperone proteins" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0005636 ! mineral homeostasis

[Term]
id: MT:0003952
name: copper level
namespace: Trait.ontology
def: "anomaly in the concentration in the body with respect to this metallic element that normally occurs in a number of proteins including amine oxidases and chaperone proteins" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0000192 ! mineral level
is_a: MT:0003951 ! copper homeostasis

[Term]
id: MT:0003953
name: hormone level
namespace: Trait.ontology
def: "aberrant tissue or circulating concentration of any substance, usually a peptide or steroid, that has a specific metabolic regulatory effect on the activity or behavior of cells expressing a receptor for the hormone" [MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0001764 ! homeostasis

[Term]
id: MT:0003954
name: Reichert's membrane morphology
namespace: Trait.ontology
def: "aberrant structure of the extraembryonic basement membrane that forms on the inner surface of the trophectoderm beginning at E6.0 and is secreted by the distal endoderm; required for the maternofetal exchange of nutrients and is important for the postgastrulation development" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002086 ! extraembryonic tissue morphology

[Term]
id: MT:0003955
name: ultimobranchial body morphology
namespace: Trait.ontology
def: "a sac-like structure emanating from the caudal-most branchial pouch of the embryo; develops into the lateral portion of the thyroid that produced calcitonin in higher vertebrates" [hdene:Howard Dene_Mouse Genome Informatics Curator]
is_a: MT:0003421 ! thyroid gland development
is_a: MT:0006031 ! branchial pouch morphology

[Term]
id: MT:0003956
name: body size
namespace: Trait.ontology
def: "anomaly in the average body weight, height and/or length of an organism compared to controls" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_pig
is_a: MT:0002089 ! postnatal growth/weight/body size

[Term]
id: MT:0003957
name: nitric oxide homeostasis
namespace: Trait.ontology
def: "anomaly in the state of equilibrium in the body of nitric oxide, a free radical gas and a potent vasodilator" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal endothelium derived relaxation factor homeostasis" EXACT []
is_a: MT:0003948 ! gas homeostasis

[Term]
id: MT:0003959
name: lean body mass
namespace: Trait.ontology
def: "aberrant fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda_Mouse Genome Informatics Curator]
is_a: MT:0002089 ! postnatal growth/weight/body size

[Term]
id: MT:0003962
name: adrenaline level
namespace: Trait.ontology
alt_id: MT:0003835
def: "aberrant concentration in the blood or tissues of this catecholamine hormone that stimulates the adrenergic receptors and that causes systemic vasoconstriction and gastrointestinal relaxation, stimulates the heart, and dilates bronchi and cerebral vessels" [pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "abnormal adrenal adrenaline level" EXACT []
synonym: "abnormal adrenal epinephrine level" EXACT []
is_a: MT:0003953 ! hormone level

[Term]
id: MT:0003963
name: corticosterone level
namespace: Trait.ontology
alt_id: MT:0003837
def: "anomalous blood or tissue concentration of this adrenocortical steroid; induces glycogen deposition and regulates sodium conservation and potassium secretion" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
subset: slim_chkn
synonym: "abnormal adrenal corticosterone level" EXACT []
is_a: ID:0000671 ! glucocorticoid level

[Term]
id: MT:0003964
name: noradrenaline level
namespace: Trait.ontology
alt_id: MT:0003836
def: "aberrant concentration of this precursor of epinephrine that is a widespread central and autonomic neurotransmitter" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal adrenal noradrenaline level" EXACT []
synonym: "abnormal adrenal norepinephrine level" EXACT []
is_a: MT:0003953 ! hormone level

[Term]
id: MT:0003965
name: pituitary hormone level
namespace: Trait.ontology
alt_id: MT:0005125
def: "aberration in the blood or tissue concentration of any of the hormones secreted by the pituitary" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0003953 ! hormone level

[Term]
id: MT:0003966
name: adrenocorticotropin level
namespace: Trait.ontology
def: "anomalous concentration of the pituitary hormone that stimulates the secretion of adrenal cortical steroids and induces growth of the adrenal cortex" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_pig
is_a: MT:0003965 ! pituitary hormone level

[Term]
id: MT:0003967
name: follicle stimulating hormone level
namespace: Trait.ontology
def: "anomalous concentration of the hormone that, in females, stimulates the graafian follicles of the ovary and assists in follicular maturation and the secretion of estradiol; in the male it stimulates the epithelium of the seminiferous tubules and is partly responsible for spermatogenesis" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0003965 ! pituitary hormone level

[Term]
id: MT:0003968
name: growth hormone level
namespace: Trait.ontology
def: "anomalous concentration of the hormone that promotes body growth, fat mobilization, and inhibition of glucose utilization" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003965 ! pituitary hormone level

[Term]
id: MT:0003969
name: luteinizing hormone level
namespace: Trait.ontology
def: "aberrant levels in the bloodstream of LH, the hormone that regulates steroid production by the interstitial cells of the testis and the ovary" [MeSH:National Library of Medicine_Medical Subject Headings, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "abnormal LH level" RELATED []
synonym: "abnormal lutropin level" RELATED []
is_a: MT:0003965 ! pituitary hormone level

[Term]
id: MT:0003970
name: prolactin level
namespace: Trait.ontology
def: "anomalous concentration of the hormone that stimulates milk secretion " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003965 ! pituitary hormone level

[Term]
id: MT:0003971
name: thyroid-stimulating hormone level
namespace: Trait.ontology
def: "anomalous concentration of the hormone that stimulates the growth and function of the thyroid gland" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_pig
is_a: MT:0003965 ! pituitary hormone level

[Term]
id: MT:0003974
name: endocardium morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the thin serous membrane, primarily composed of endothelial tissue, that lines the interior of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
relationship: part_of MT:0000266 ! cardiac morphology

[Term]
id: MT:0003976
name: circulating VLDL triglyceride level
namespace: Trait.ontology
def: "lower than average concentration in the blood of very low density lipoprotein, which normally transports triglycerides from the intestine and liver to muscle and adipose tissue" [brs:Beverly Richards-Smith_Mouse Genome Informatics Curator]
is_a: MT:0002644 ! circulating triglyceride level

[Term]
id: MT:0003977
name: circulating carnitine level
namespace: Trait.ontology
def: "aberrant concentration in the blood of carnitine, a quaternary ammonium amino acid derivative involved in transport of fatty acids across the mitochondrial membrane" [brs:Beverly Richards-Smith_Mouse Genome Informatics Curator]
is_a: MT:0000179 ! blood chemistry

[Term]
id: MT:0003984
name: embryonic growth rate
namespace: Trait.ontology
alt_id: MT:0001692
def: "slow or limited development during the embryonic period (sensu Mus: up to E14, or the completion of organogenesis)" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "delayed embryonic development" EXACT []
is_a: MT:0001672 ! embryogenesis/ development
is_a: MT:0002088 ! embryonic growth/weight/body size

[Term]
id: MT:0003985
name: renal fibrosis
namespace: Trait.ontology
def: "formation of fibrous tissue in the kidney as a result of repair or a reactive process" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002135 ! kidney morphology

[Term]
id: MT:0003986
name: cochlear ganglion size
namespace: Trait.ontology
def: "reduced size of the cochlear ganglion or of the sensory neuron cell bodies that conveys auditory sensation from the organ of Corti to the hindbrain and resides on the cochlear part of the vestibulocochlear nerve (eighth cranial nerve)" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0002855 ! cochlear ganglion morphology

[Term]
id: MT:0003987
name: vestibular ganglion size
namespace: Trait.ontology
def: "reduced size of the vestibular ganglion or of the sensory neuron cell bodies associated with the eighth cranial nerve" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0002856 ! vestibular ganglion morphology

[Term]
id: MT:0003989
name: barrel cortex morphology
namespace: Trait.ontology
def: "structure of the discrete functional units of the somatosensory cortex that processes tactile information derived from the vibrissae" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0000860 ! primary somatosensory cortex morphology

[Term]
id: MT:0003993
name: ventral spinal root morphology
namespace: Trait.ontology
def: "any anomaly, deformity, or malformation of the anterior bundle of nerves emerging from the spinal cord to join with the posterior/dorsal nerve bundle at each spinal cord segment to form one of the 31 paired peripheral nerves" [brs:Beverly Richards-Smith_Mouse Genome Informatics Curator]
is_a: MT:0001077 ! spinal nerve morphology

[Term]
id: MT:0003994
name: dorsal spinal root morphology
namespace: Trait.ontology
def: "any anomaly, deformity, or malformation of the posterior bundle of nerves emerging from the spinal cord to join with the anterior/ventral nerve bundle at each spinal cord segment to form one of the 31 paired peripheral nerves" [brs:Beverly Richards-Smith_Mouse Genome Informatics Curator]
is_a: MT:0001077 ! spinal nerve morphology

[Term]
id: MT:0003995
name: uterine artery integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the branch of the internal iliac artery that supplies the uterus and the upper part of the vagina" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0001120 ! uterus morphology
is_a: MT:0003410 ! artery integrity

[Term]
id: MT:0004002
name: jejunum morphology
namespace: Trait.ontology
def: "malformation of the portion of the small intestine that extends from the duodenum to the ileum" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0000496 ! small intestine morphology

[Term]
id: MT:0004003
name: blood vessel endothelial cell function
namespace: Trait.ontology
def: "function of the cells that line the vasculature" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "vascular endothelial cell fundtion" RELATED []
is_a: MT:0000249 ! blood vessel physiology

[Term]
id: MT:0004005
name: intestinal smooth muscle contractility
namespace: Trait.ontology
def: "inability or reduced ability of intestinal smooth muscle to shorten or to develop increased tension" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0000740 ! smooth muscle contractility

[Term]
id: MT:0004006
name: jejunal smooth muscle contractility
namespace: Trait.ontology
def: "inability or reduced ability of the jejunal smooth muscle to shorter or to develop increased tension" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0004005 ! intestinal smooth muscle contractility

[Term]
id: MT:0004007
name: lung blood vessel morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the blood vessels of the lung" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "lung vascular morphology" RELATED []
synonym: "pulmonary vasculature" RELATED []
xref: MP:0004007
is_a: MT:0001175 ! lung morphology
is_a: MT:0001614 ! blood vessel morphology

[Term]
id: MT:0004008
name: GABA receptor currents
namespace: Trait.ontology
def: "change in the measured amplitude or duration of response to stimulation of GABA receptors" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal gamma-amino-n-butyric acid receptor currents" EXACT []
is_a: MT:0002206 ! CNS synaptic transmission

[Term]
id: MT:0004009
name: diastolic filling velocity
namespace: Trait.ontology
def: "rate of fluid inflow to the heart during diastole; usually measured in the left ventricle" [RGD:cur "Rat Genome Database submission"]
is_a: MT:0002128 ! blood circulation

[Term]
id: MT:0004014
name: uterine environment
namespace: Trait.ontology
def: "anomaly or inability of the uterus to support embryonic development" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0003699 ! female reproductive system physiology

[Term]
id: MT:0004015
name: oviduct environment
namespace: Trait.ontology
def: "anomaly or inability of the oviduct to support egg viability" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0003699 ! female reproductive system physiology

[Term]
id: MT:0004016
name: bone mass
namespace: Trait.ontology
def: "a reduction in the total amount of bone tissue contained in the skeleton" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0003795 ! bone structure

[Term]
id: MT:0004017
name: duplex kidney
namespace: Trait.ontology
def: "a kidney that is split into two separate collecting systems; there may be a duplex ureter or a single ureter; may present unilaterally or bilaterally" [rbabiuk:Randall Babiuk_Mouse Genome Informatics Curator]
is_a: MT:0002135 ! kidney morphology

[Term]
id: MT:0004018
name: galactose homeostasis
namespace: Trait.ontology
def: "anomaly in the state of equilibrium or processing in the body with respect to galactose in the fluids and tissues" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001764 ! homeostasis

[Term]
id: MT:0004019
name: vitamin homeostasis
namespace: Trait.ontology
def: "anomaly in the state of equilibrium in the body of organic substances found in food and are not synthesized by the body and are necessary in trace amounts for normal metabolic function" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001764 ! homeostasis

[Term]
id: MT:0004020
name: amniotic fluid volume
namespace: Trait.ontology
def: "abnormally high amniotic fluid volume; may result from maternal diabetes, chromosomal abnormalities or other congenital abnormalities" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0001784 ! fluid regulation

[Term]
id: MT:0004021
name: rod electrophysiology
namespace: Trait.ontology
def: "anomaly in the function of dark adapted vision mediated by the rods" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal scotopic response" EXACT []
is_a: MT:0005551 ! eye electrophysiology

[Term]
id: MT:0004022
name: cone electrophysiology
namespace: Trait.ontology
def: "anomaly in the function of light adapted vision mediated by the cones" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal photopic response" EXACT []
is_a: MT:0005551 ! eye electrophysiology

[Term]
id: MT:0004023
name: chromosome number
namespace: Trait.ontology
def: "chromosome count is other than the expected diploid chromosome number" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0003111 ! nucleus morphology

[Term]
id: MT:0004024
name: aneuploidy
namespace: Trait.ontology
def: "chromosome count is not an exact multiple of the haploid number " [llw2:Linda Washburn_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0004023 ! chromosome number

[Term]
id: MT:0004025
name: polyploidy
namespace: Trait.ontology
def: "more than two chromosome sets are present" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0004023 ! chromosome number

[Term]
id: MT:0004026
name: monosomy
namespace: Trait.ontology
def: "one chromosome missing from an otherwise diploid chromosome set" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0004024 ! aneuploidy

[Term]
id: MT:0004027
name: trisomy
namespace: Trait.ontology
def: "presence of an extra chromosome in an otherwise diploid chromosome set" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0004024 ! aneuploidy

[Term]
id: MT:0004028
name: chromosome breakage
namespace: Trait.ontology
alt_id: MT:0002008
def: "chromosome instability in the from of increased frequency of spontaneous breakage with or without rearrangements" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
synonym: "chromosomal instability" EXACT []
is_a: MT:0003111 ! nucleus morphology

[Term]
id: MT:0004029
name: spontaneous chromosome breakage
namespace: Trait.ontology
def: "chromosome breakage due to inherent instability of chromosomes" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0004028 ! chromosome breakage

[Term]
id: MT:0004030
name: induced chromosome breakage
namespace: Trait.ontology
def: "chromosome breakage following treatment with a DNA-damaging agent " [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0004028 ! chromosome breakage

[Term]
id: MT:0004031
name: insulitis
namespace: Trait.ontology
def: "a histological change in the islets of Langerhans characterized by edema and the infiltration of small numbers of white blood cells" [rbabiuk:Randall Babiuk_Mouse Genome Informatics Curator]
is_a: MT:0001869 ! pancreas inflammation

[Term]
id: MT:0004032
name: interventricular groove morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the indentation dividing the two ventricles, comprised of the sulcus interventricularis anterior and the sulcus interventricularis posterior" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "interventricular sulcus morphology" EXACT []
relationship: part_of MT:0000266 ! cardiac morphology

[Term]
id: MT:0004034
name: belly blaze
namespace: Trait.ontology
def: "the appearance of a stripe or zigzag of white fur on the ventrum" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0002075 ! coat color

[Term]
id: MT:0004035
name: sublingual gland morphology
namespace: Trait.ontology
def: "malformation of the small mucin-producing salivary glands in the floor of the mouth beneath the tongue, anterior to the submandibular gland" [hdene:Howard Dene_Mouse Genome Informatics Curator]
is_a: MT:0003792 ! major salivary gland morphology

[Term]
id: MT:0004036
name: muscle relaxation
namespace: Trait.ontology
def: "altered ability of the muscle to lengthen following contractions" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0002106 ! muscle physiology

[Term]
id: MT:0004038
name: lymphangiectasis
namespace: Trait.ontology
def: "dilation of the lymphatic vessels, the basic process that may result in the formation of a lymphangioma" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:71816]
synonym: "dilated lymphatic vessels" EXACT []
synonym: "lymphectasia" EXACT []
synonym: "telangiectasia lymphatica" EXACT []
is_a: MT:0001879 ! lymphatic vessel morphology

[Term]
id: MT:0004039
name: cardiac cell glucose uptake
namespace: Trait.ontology
def: "ability of the cells of the heart to take in glucose" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0001544 ! cardiovascular system physiology

[Term]
id: MT:0004040
name: susceptibility to kidney reperfusion injury
namespace: Trait.ontology
def: "a change in the likelihood or extent of damage to the kidney when the blood supply is restored after a period of ischemia " [brs:Beverly Richards-Smith_Mouse Genome Informatics Curator]
is_a: MT:0002136 ! kidney physiology

[Term]
id: MT:0004043
name: pH regulation
namespace: Trait.ontology
def: "anomaly in the function of the buffer systems of the body in combination with the respiratory and renal systems that control the relative acidity or alkalinity of the body, as measured by the concentration of hydrogen ion" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
subset: slim_pig
is_a: MT:0001764 ! homeostasis

[Term]
id: MT:0004045
name: cell cycle checkpoint function
namespace: Trait.ontology
def: "anomaly in the amount of time spent at the points in the cell cycle (end of G1 phase, end of G2 phase, and during metaphase) which prevent the cell from progressing to the next phase when conditions are unfavorable" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003077 ! cell cycle

[Term]
id: MT:0004046
name: mitosis
namespace: Trait.ontology
def: "anomaly in the process of cell division including both division of the nucleus (karyokinesis) and the cytoplasm (cytokinesis) " [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003077 ! cell cycle

[Term]
id: MT:0004047
name: milk composition
namespace: Trait.ontology
def: "anomaly in the protein or lipid content or the appearance of milk" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
subset: slim_cattle
relationship: part_of MT:0001882 ! lactation

[Term]
id: MT:0004049
name: acute promyelocytic leukemia
namespace: Trait.ontology
def: "rapid onset of abnormal leukocyte proliferation, manifesting as a severe bleeding disorder from coagulation abnormalities, and bone marrow infiltration of abnormal promyelocytes and myelocytes" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002026 ! leukemia

[Term]
id: MT:0004050
name: renal sympathetic nerve activity
namespace: Trait.ontology
is_a: MT:0002136 ! kidney physiology

[Term]
id: MT:0004053
name: synchondrosis
namespace: Trait.ontology
def: "anomalous or persistent cartilaginous fusion of two bones " [J:102870, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000164 ! cartilage development

[Term]
id: MT:0004054
name: periocular mesenchyme morphology
namespace: Trait.ontology
def: "malformation in the mesenchymal cells that give rise to the corneal endothelium, corneal stroma, sclera, iris stroma, ciliary muscle, ciliary stroma, and trabecular meshwork of the eye" [J:102847, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001286 ! eye development

[Term]
id: MT:0004056
name: heart muscle compact layer integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the outer, dense layer of the myocardium" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "myocardial compact layer integrity" RELATED []
relationship: part_of MT:0000058 ! heart muscle compact layer morphology
relationship: part_of MT:0000073 ! heart muscle integrity

[Term]
id: MT:0004058
name: ventricle papillary muscle integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of one of the group of myocardial bundles which terminate in the chordae tendineae that attach to the cusps of the atrioventricular valves; each ventricle has an anterior and a posterior papillary muscle; the right ventricle sometimes has a septal papillary muscle" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "musculus papillaris integrity" RELATED []
synonym: "ventricular papillary muscle integrity" RELATED []
relationship: part_of MT:0000063 ! ventricle papillary muscle morphology
relationship: part_of MT:0000073 ! heart muscle integrity

[Term]
id: MT:0004062
name: right atrium volume
namespace: Trait.ontology
def: "physical bulk of or total amount of space encompassed by the left upper chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "right atrial mass" RELATED []
synonym: "right atrial volume" RELATED []
synonym: "right atrium mass" RELATED []
relationship: part_of MT:0000005 ! right atrium size

[Term]
id: MT:0004063
name: left atrium volume
namespace: Trait.ontology
def: "physical bulk of or total amount of space encompassed by the left upper chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "left atrial mass" RELATED []
synonym: "left atrial volume" RELATED []
synonym: "left atrium mass" RELATED []
relationship: part_of MT:0000012 ! left atrium size

[Term]
id: MT:0004065
name: susceptibility to induced muscular atrophy
namespace: Trait.ontology
def: "greater than expected wasting of muscle tissue after experimental manipulation (starvation, neurectomy, immobilization, etc)" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002106 ! muscle physiology

[Term]
id: MT:0004066
name: Henson's node morphology
namespace: Trait.ontology
def: "malformation of cells in the small pit at the anterior end of the primitive streak that are important in determining left-right asymmetry" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal embryonic node morphology" EXACT []
is_a: MT:0002231 ! primitive streak morphology

[Term]
id: MT:0004067
name: ventricle trabeculae morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the supporting bundles of muscular fibers lining the walls of the ventricles of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "ventricular trabeculae morphology" RELATED []
relationship: part_of MT:0005294 ! heart ventricle morphology

[Term]
id: MT:0004069
name: muscle spindle morphology
namespace: Trait.ontology
def: "anomalous structure of the sensory organs in muscle that are involved in the stretch reflex" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
is_a: MT:0000990 ! skeletal muscle mechanoreceptor morphology

[Term]
id: MT:0004074
name: Schwann cell precursor morphology
namespace: Trait.ontology
def: "malformation or absence of the progenitors of cells that sheath the axons of the peripheral nervous system" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0001106 ! Schwann cell morphology

[Term]
id: MT:0004075
name: Schwann cell precursor number
namespace: Trait.ontology
def: "fewer numbers than normal of the progenitors of cells that sheath the axons of the peripheral nervous system" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0004074 ! Schwann cell precursor morphology

[Term]
id: MT:0004076
name: vitelline vascular remodeling
namespace: Trait.ontology
def: "anomaly in the conversion of the primary (honeycomb-like) vascular plexus of the yolk sac into a mature vascular network" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003229 ! vitelline vascular morphology

[Term]
id: MT:0004077
name: striatum morphology
namespace: Trait.ontology
def: "malformation of a large cluster of dopaminergic nerve cells, consisting of the caudate nucleus and the putamen, that controls movement, balance, and walking" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal neostriatum morphology" EXACT []
synonym: "abnormal striate body" EXACT []
is_a: MT:0000787 ! telencephalon morphology
is_a: MT:0006007 ! basal ganglion morphology

[Term]
id: MT:0004078
name: caudate nucleus morphology
namespace: Trait.ontology
def: "malformation of one or both C-shaped structures containing input neurons involved with control of voluntary movement in the brain" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
is_a: MT:0004102 ! dorsal striatum morphology

[Term]
id: MT:0004079
name: putamen morphology
namespace: Trait.ontology
def: "malformation of the lens-shaped basal ganglion involved with control of voluntary movement in the brain" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
is_a: MT:0004102 ! dorsal striatum morphology

[Term]
id: MT:0004080
name: nucleus accumbens morphology
namespace: Trait.ontology
def: "malformation in the group of neurons located at the head of the caudate nucleus and anterior to the putamen; these neurons normally are involved in sensations of pleasure and reactions to addictive substances " [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal accumbens nucleus morphology" EXACT []
synonym: "abnormal Nacc morphology" EXACT []
is_a: MT:0004103 ! ventral striatum morphology
is_a: MT:0004166 ! limbic system morphology

[Term]
id: MT:0004081
name: globus pallidus morphology
namespace: Trait.ontology
def: "malformation of one of the basal ganglia involved with control of voluntary movement in the brain; consists of an external and an internal segment" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal paleostriatum" EXACT []
synonym: "abnormal pallidum morphology" EXACT []
is_a: MT:0000830 ! diencephalon morphology
is_a: MT:0006007 ! basal ganglion morphology

[Term]
id: MT:0004082
name: habenula development
namespace: Trait.ontology
def: "anomaly in the group of nuclei that makes up the small eminence on the dorsomedial surface of the thalamus, just in front of the dorsal commissure on the lateral edge of the habenular trigone" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: Note that the habenula term originally denoted the stalk of the pineal gland, but now refers to the habenular nucleus, a neighboring group of neurons in the epithalamus
synonym: "abnormal pineal peduncle" EXACT []
is_a: MT:0000840 ! epithalamus morphology

[Term]
id: MT:0004083
name: polysyndactyly
namespace: Trait.ontology
def: "greater than 5 digits present on an autopod with interdigital webbing also present" [rbabiuk:Randall Babiuk_Mouse Genome Informatics Curator]
is_a: MT:0000562 ! polydactyly
is_a: MT:0000564 ! syndactyly

[Term]
id: MT:0004084
name: cardiac muscle relaxation
namespace: Trait.ontology
def: "ability of the cardiac/heart muscle to lengthen following contractions, often measured by dP/dt min" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0001544 ! cardiovascular system physiology
is_a: MT:0004036 ! muscle relaxation

[Term]
id: MT:0004085
name: heartbeat
namespace: Trait.ontology
def: "regularly spaced contractions of the heart" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0001544 ! cardiovascular system physiology

[Term]
id: MT:0004087
name: muscle fiber morphology
namespace: Trait.ontology
def: "malformed or poorly developed muscle fibers, the cylindrical multinucleated muscle cells that contract when stimulated" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
subset: slim_pig
is_a: MT:0002108 ! muscle morphology

[Term]
id: MT:0004088
name: sarcoplasmic reticulum morphology
namespace: Trait.ontology
def: "any structural abnormality in the endoplasmic reticulum of skeletal and cardiac muscle, i.e. the complex of vesicles, tubules, and cisternae that form a continuous structure around striated myofibrils, with a repetition of structure within each sarcomere " [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004087 ! muscle fiber morphology

[Term]
id: MT:0004089
name: dilated sarcoplasmic reticulum
namespace: Trait.ontology
def: "an expansion in the volume in the endoplasmic reticulum of skeletal and cardiac muscle, i.e. the complex of vesicles, tubules, and cisternae that form a continuous structure around striated myofibrils, with a repetition of structure within each sarcomere" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004088 ! sarcoplasmic reticulum morphology

[Term]
id: MT:0004090
name: sarcomere morphology
namespace: Trait.ontology
def: "any structural abnormality in the segment of a myofibril between two Z lines comprised of multi-protein complexes composed of three different filament systems; these systems work together to contract and relax muscle" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_pig
is_a: MT:0004087 ! muscle fiber morphology

[Term]
id: MT:0004091
name: Z lines morphology
namespace: Trait.ontology
def: "any structural abnormality in the cross-striation bisecting the I band of striated muscle myofibrils and serving as the anchoring point of actin filaments at either end of the sarcomere" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "abnormal intermediate disk" EXACT []
synonym: "abnormal Z band" EXACT []
synonym: "abnormal Z disk" EXACT []
is_a: MT:0004090 ! sarcomere morphology

[Term]
id: MT:0004092
name: Z line number
namespace: Trait.ontology
def: "count of the cross-striation bisecting the I band of striated muscle myofibrils and serving as the anchoring point of actin filaments at either end of the sarcomere" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004091 ! Z lines morphology

[Term]
id: MT:0004093
name: Z line pattern
namespace: Trait.ontology
def: "organization of the cross-striation bisecting the I band of striated muscle myofibrils and serving as the anchoring point of actin filaments at either end of the sarcomere" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004091 ! Z lines morphology

[Term]
id: MT:0004094
name: M line morphology
namespace: Trait.ontology
def: "any structural anomaly in the band in the center of the H band that contains proteins that crosslink the thick filament system (myosins) and the M-band part of the elastic filaments" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004090 ! sarcomere morphology

[Term]
id: MT:0004095
name: ocular distichiasis
namespace: Trait.ontology
def: "presence of a double row of eyelashes on an eyelid, one or both of which are turned in against the eyeball" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:83436]
is_a: MT:0001340 ! eyelid morphology

[Term]
id: MT:0004096
name: midbrain-hindbrain boundary development
namespace: Trait.ontology
def: "anomaly in the formation of the midbrain-hindbrain domain, comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages; an organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0003864 ! midbrain development

[Term]
id: MT:0004097
name: cerebellar cortex morphology
namespace: Trait.ontology
def: "any structural anomaly of the thin mantle of gray matter that covers the surface of each cerebral hemisphere, including the six layers of nerve cells and the nerve pathways that connect them; together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
is_a: MT:0000849 ! cerebellum morphology

[Term]
id: MT:0004098
name: granule neuron morphology
namespace: Trait.ontology
def: "any structural anomaly of the small neurons of the granule cell layer that send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal granule cell" EXACT []
is_a: MT:0000886 ! cerebellar granule layer morphology

[Term]
id: MT:0004099
name: cerebellar glomerulus morphology
namespace: Trait.ontology
def: "any structural anomaly of an intertwined cluster of nerve fibers surrounded by glia where mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal cerebellar glomeruli" EXACT []
is_a: MT:0000886 ! cerebellar granule layer morphology

[Term]
id: MT:0004100
name: spinal cord interneuron morphology
namespace: Trait.ontology
def: "malformation or absence of neurons that exclusively interact with other neurons in the spinal cord" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0006004 ! interneuron morphology

[Term]
id: MT:0004101
name: brain interneuron morphology
namespace: Trait.ontology
def: "malformation or absence of neurons that exclusively interact with other neurons in the brain; this includes most brain neuronal cell types" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0006004 ! interneuron morphology

[Term]
id: MT:0004102
name: dorsal striatum morphology
namespace: Trait.ontology
def: "any structural abnormality of the regions of the caudate nucleus and the putamen that lie dorsal to the anterior commissure" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal caudate putamen complex" EXACT []
synonym: "abnormal caudate-putamen morphology" EXACT []
synonym: "abnormal caudatoputamen morphology" EXACT []
synonym: "abnormal dorsal basal ganglia" EXACT []
is_a: MT:0004077 ! striatum morphology

[Term]
id: MT:0004103
name: ventral striatum morphology
namespace: Trait.ontology
def: "any structural abnormality of the regions of the nucleus accumbens and some nuclei of the olfactory tubercle that lie ventral to the anterior commissure" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0004077 ! striatum morphology

[Term]
id: MT:0004104
name: eye shape
namespace: Trait.ontology
def: "alteration in the size, shape or organization of cells of the eye " [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0002092 ! eye morphology

[Term]
id: MT:0004105
name: corneal abrasion
namespace: Trait.ontology
def: "scraping away or denuding of the corneal surface" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0001312 ! cornea morphology

[Term]
id: MT:0004106
name: lymphatic vessel cell number
namespace: Trait.ontology
def: "increased cell number in lymphatic vessels" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0001879 ! lymphatic vessel morphology

[Term]
id: MT:0004107
name: thoracic duct morphology
namespace: Trait.ontology
def: "any structural abnormality in the largest lymph vessel in the body, beginning at the cisterna chyli at about the level of the second lumbar vertebra" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "abnormal ductus thoracicus" EXACT []
synonym: "abnormal Pecquet duct" EXACT []
synonym: "abnormal van Horne canal" EXACT []
is_a: MT:0001879 ! lymphatic vessel morphology

[Term]
id: MT:0004108
name: esophageal peristalsis
namespace: Trait.ontology
def: "altered esophageal movement characterized by waves of alternate circular contraction and relaxation of the muscular walls that move the esophagus contents forward" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001664 ! digestion

[Term]
id: MT:0004109
name: Sertoli cell development
namespace: Trait.ontology
def: "anomalous differentiation of cells that support germ cell differentiation in males" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0003830 ! testis development

[Term]
id: MT:0004111
name: coronary artery morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of any of the arteries that branch from the aorta to supply blood to the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
xref: MP:0004111
is_a: MT:0002191 ! artery morphology

[Term]
id: MT:0004112
name: arteriole integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the small diameter vessels that branch from the arteries and lead to the capillaries" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0003410 ! artery integrity

[Term]
id: MT:0004113
name: aortic arch morphology
namespace: Trait.ontology
def: "structural completeness, soundness, or configuration of the portion of the descending aorta proceeding from the arch of the aorta and extending to the diaphram" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
relationship: part_of MT:0000272 ! aorta morphology

[Term]
id: MT:0004114
name: atrioventricular node morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the small nodular mass of specialized muscle fibers located in the interatrial septum near the opening of the coronary sinus; this node gives rise to the electrical connection between the atria and ventricles and responds to the sinoatrial node" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
relationship: part_of MT:0000019 ! right atrium morphology
relationship: part_of MT:0004123 ! impulse conducting system morphology

[Term]
id: MT:0004115
name: sinoatrial node morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the small mass of modified cardiac muscle fibers located at the junction of the superior vena cava and the right atrium that is the source of contraction impulses for the heart" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "pacemaker morphology" EXACT []
synonym: "sinus node morphology" EXACT []
relationship: part_of MT:0000019 ! right atrium morphology
relationship: part_of MT:0004123 ! impulse conducting system morphology

[Term]
id: MT:0004116
name: atrioventricular bundle conduction
namespace: Trait.ontology
def: "transfer of cardiac electrical impulses through the specialized cardiac muscle fibers that originates in the atrioventricular node and extends into the ventricle" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "bundle of His conduction" EXACT []
is_a: MT:0003137 ! impulse conducting system function

[Term]
id: MT:0004117
name: atrioventricular bundle morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the specialized cardiac muscle fibers that originate in the atrioventricular node and extend into the ventricle" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
relationship: part_of MT:0000019 ! right atrium morphology
relationship: part_of MT:0004123 ! impulse conducting system morphology

[Term]
id: MT:0004118
name: baroreceptor morphology
namespace: Trait.ontology
def: "anomaly in the sensory nerve endings in the wall of the atria of the heart, vena cava, aortic arch and carotid sinus that are sensitive to changes in blood pressure" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal pressoreceptor morphology" EXACT []
is_a: MT:0000972 ! mechanoreceptor morphology

[Term]
id: MT:0004121
name: sarcolemma morphology
namespace: Trait.ontology
def: "structural anomaly in the plasma membrane of a muscle fiber that is capable of conducting electrical impulses" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal myolemma morphology" EXACT []
is_a: MT:0004087 ! muscle fiber morphology

[Term]
id: MT:0004122
name: sinoatrial node function
namespace: Trait.ontology
def: "function of the sinoatrial node" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0001636 ! heartbeat regularity

[Term]
id: MT:0004123
name: impulse conducting system morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the impulse-conducting system composed of modified cardiac muscle and having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
xref: MP:0004123
relationship: part_of MT:0000266 ! cardiac morphology

[Term]
id: MT:0004124
name: Purkinje fiber morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the cardiac muscle fibers composing the terminal portion of the heart conduction system located in the ventricle" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
relationship: part_of MT:0004123 ! impulse conducting system morphology

[Term]
id: MT:0004125
name: venule integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the minute vessels that collect deoxygenated blood from the capillary plexuses returns it to the veins" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0000118 ! vein integrity

[Term]
id: MT:0004127
name: hypodermis thickness
namespace: Trait.ontology
def: "increase in the width of the innermost and thickest layer of the skin composed of loose connective tissue containing adipocytes" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0003705 ! hypodermis morphology

[Term]
id: MT:0004128
name: adipocyte morphology
namespace: Trait.ontology
is_a: MT:0000003 ! adipose tissue morphology

[Term]
id: MT:0004129
name: respiratory quotient
namespace: Trait.ontology
def: "the ratio of the volume of carbon dioxide released to oxygen consumed by a body tissue or an organism" [J:94416]
synonym: "abnormal respiratory exchange ratio" EXACT []
is_a: MT:0003948 ! gas homeostasis

[Term]
id: MT:0004130
name: muscle cell glucose uptake
namespace: Trait.ontology
def: "anomaly in the ability of muscle cells to take in glucose" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002106 ! muscle physiology

[Term]
id: MT:0004131
name: embryonic ciliary morphology
namespace: Trait.ontology
def: "any structural malformation of the earliest cilia of the mouse embryo found on the cells of the embryonic node" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004066 ! Henson's node morphology

[Term]
id: MT:0004133
name: heterotaxia
namespace: Trait.ontology
def: "abnormal arrangement of organs or parts of the body in relation to each other" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "heterotaxis" EXACT []
synonym: "heterotaxy" EXACT []
is_a: MT:0002089 ! postnatal growth/weight/body size

[Term]
id: MT:0004134
name: chest morphology
namespace: Trait.ontology
def: "malformation of the part of the body between the neck and the abdomen" [J:59168, smb:Susan M. Bello_Mouse Genome Informatics Curator]
subset: slim_cattle
synonym: "abnormal thorax morphology" EXACT []
is_a: MT:0002089 ! postnatal growth/weight/body size

[Term]
id: MT:0004135
name: mammary gland embryonic development
namespace: Trait.ontology
def: "aberration in the differentiation of the mammary gland during early embryogenesis" [llw2:Linda Washburn_Mouse Genome Informatics Curator, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000628 ! mammary gland development

[Term]
id: MT:0004136
name: tongue muscle morphology
namespace: Trait.ontology
def: "anomalous structure or development of the muscular portion of the tongue" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000759 ! skeletal muscle morphology

[Term]
id: MT:0004137
name: gastric surface mucous cell morphology
namespace: Trait.ontology
def: "malformation of the mucus secreting epithelial cells that line the luminal surface of the stomach, gastric pits and gastric glands" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0005209 ! gastric mucosa morphology

[Term]
id: MT:0004138
name: mucous neck cell morphology
namespace: Trait.ontology
def: "malformation of the mucin-producing epithelial cells present in the neck of the gastric glands " [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0003892 ! gastric gland morphology

[Term]
id: MT:0004139
name: gastric parietal cell morphology
namespace: Trait.ontology
def: "malformation of the gastric acid producing epithelial cells that are distributed throughout the length of the gastric gland " [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
synonym: "abnormal parietal cell morphology" EXACT []
is_a: MT:0003892 ! gastric gland morphology

[Term]
id: MT:0004140
name: chief cell morphology
namespace: Trait.ontology
def: "malformation of the pepsinogen producing epithelial cells that are clustered at the base of the gastric gland " [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0003892 ! gastric gland morphology

[Term]
id: MT:0004141
name: enteroendocrine cell morphology
namespace: Trait.ontology
def: "malformation of the somatostatin and gastrin secreting epithelial cells present throughout the epithelium of the digestive tract" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0000511 ! intestinal mucosa morphology
is_a: MT:0003892 ! gastric gland morphology

[Term]
id: MT:0004142
name: muscle tone
namespace: Trait.ontology
def: "anomaly in the resting tautness or laxity of a muscle, normally somewhere in the middle of the range between total contraction and total relaxation" [hdene:Howard Dene_Mouse Genome Informatics Curator]
is_a: MT:0002106 ! muscle physiology

[Term]
id: MT:0004145
name: muscle electrophysiology
namespace: Trait.ontology
def: "anomaly in the function of the musculature as it relates to electrical phenomena" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal muscle electrical activity" EXACT []
is_a: MT:0002106 ! muscle physiology

[Term]
id: MT:0004146
name: M line number
namespace: Trait.ontology
def: "count of the band in the center of the H band that contains proteins that crosslink the thick filament system (myosins) and the M-band part of the elastic filaments" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004094 ! M line morphology

[Term]
id: MT:0004147
name: porphyrin level
namespace: Trait.ontology
def: "elevated concentration of porphyrins or protoporphyrins" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001764 ! homeostasis

[Term]
id: MT:0004150
name: caveolae morphology
namespace: Trait.ontology
def: "physical appearance of the small pockets, vesicles, caves, or recesses communicating with the outside of a cell and extending inward, indenting the cytoplasm and the cell membrane" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0003950 ! plasma membrane morphology

[Term]
id: MT:0004152
name: circulating iron level
namespace: Trait.ontology
def: "anomalous blood concentration of this metallic element that normally occurs in the heme of hemoglobin, myoglobin, transferrin, ferritin, and iron-containing porphyrins; it is an essential component of enzymes such as catalase, peroxidase, and various cytochromes" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000179 ! blood chemistry
is_a: MT:0001770 ! iron level

[Term]
id: MT:0004153
name: renal tubule apoptosis
namespace: Trait.ontology
def: "increase in the number of renal tubule cells undergoing programmed cell death" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0002703 ! renal tubule morphology

[Term]
id: MT:0004154
name: renal tubular necrosis
namespace: Trait.ontology
def: "pathological cell death in the proximal and/or distal renal tubules, usually due to irreversible damage " [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0003946 ! renal necrosis

[Term]
id: MT:0004155
name: susceptibility to induced pancreatitis
namespace: Trait.ontology
def: "level of inflammatory response in the pancreatic tissue after experimental manipulation" [honda:Hiraoki Onda_Mouse Genome Informatics Curator]
is_a: MT:0001869 ! pancreas inflammation

[Term]
id: MT:0004162
name: mammillary body morphology
namespace: Trait.ontology
def: "any malformation or absence of the protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000837 ! hypothalamus morphology

[Term]
id: MT:0004163
name: adenophysis morphology
namespace: Trait.ontology
def: "any malformation or absence of the anterior part of the pituitary that secretes a variety of hormones; its function is regulated by the hypothalamus" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal adenohypophysis morphology" EXACT []
is_a: MT:0000633 ! pituitary gland morphology

[Term]
id: MT:0004164
name: neurophysis morphology
namespace: Trait.ontology
def: "any malformation or absence of the part of the pituitary gland that secretes hormones involved in blood pressure regulation" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000633 ! pituitary gland morphology

[Term]
id: MT:0004165
name: lateral geniculate nucleus morphology
namespace: Trait.ontology
def: "any malformation or absence of the group of neurons that serve as the primary processor of visual information received from the retina via the optic tract and send processed information to the visual cortex of the occipital lobe" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal LGN morphology" EXACT []
is_a: MT:0000832 ! thalamus morphology

[Term]
id: MT:0004166
name: limbic system morphology
namespace: Trait.ontology
def: "any malformation or absence of any of a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory; these structures act together to control the endocrine system and the autonomic nervous system" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000783 ! forebrain morphology

[Term]
id: MT:0004167
name: cingulate gyrus morphology
namespace: Trait.ontology
def: "any malformation or absence of the ridge in the cerebral cortex located dorsal to the corpus callosum that controls autonomic functions regulating heart rate and blood pressure as well as cognitive and attentional processing" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal callosal gyrus morphology" EXACT []
synonym: "abnormal falciform lobe" EXACT []
is_a: MT:0000788 ! cerebral cortex morphology
is_a: MT:0004169 ! fornicate gyrus morphology

[Term]
id: MT:0004168
name: parahippocampal gyrus morphology
namespace: Trait.ontology
def: "any malformation or absence of the ridge in the cerebral cortex that contains the olfactory cortex and that plays a role in the formation of topographical memory" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000801 ! temporal lobe morphology
is_a: MT:0004169 ! fornicate gyrus morphology

[Term]
id: MT:0004169
name: fornicate gyrus morphology
namespace: Trait.ontology
def: "any malformation or absence of the horseshoe-shaped gyrus of the cerebral cortex that consists of the cingulate gyrus and the parahippocampal gyrus" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal limbic lobe morphology" EXACT []
is_a: MT:0004166 ! limbic system morphology

[Term]
id: MT:0004170
name: orbitofrontal cortex morphology
namespace: Trait.ontology
def: "any malformation or absence of the region of the cerebral cortex covering the basal surface of the frontal lobes; this region normally controls emotion and decision making" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000798 ! frontal lobe morphology
is_a: MT:0004166 ! limbic system morphology

[Term]
id: MT:0004171
name: pallium development
namespace: Trait.ontology
def: "anomaly in the progression of the formation of the roof region of the telencephalon" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000934 ! telencephalon development

[Term]
id: MT:0004172
name: subpallium development
namespace: Trait.ontology
def: "anomaly in the progression of the formation of the base region of the telencephalon" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000934 ! telencephalon development

[Term]
id: MT:0004173
name: intervertebral disk morphology
namespace: Trait.ontology
def: "malformation of the cartilaginous and gelatinous structure found between vertebrae" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal intervertebral disc morphology" EXACT []
is_a: MT:0000137 ! vertebrae morphology
is_a: MT:0000163 ! cartilage morphology

[Term]
id: MT:0004174
name: spine curvature
namespace: Trait.ontology
def: "deviation from the typical S-shape of the spine" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002114 ! axial skeleton morphology

[Term]
id: MT:0004179
name: transmission ratio distortion
namespace: Trait.ontology
def: "the occurrence of an allele or haplotype in the offspring of an organism at skewed Mendelian ratios" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0005395 ! other trait

[Term]
id: MT:0004181
name: carotid artery integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of any of the four arteries (two on each side of the neck; right and left internal carotid arteries, and right and left external carotid arteries) that deliver oxygen-rich blood from the heart to the head and brain" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0003410 ! artery integrity

[Term]
id: MT:0004182
name: spermiation
namespace: Trait.ontology
def: "failure of mature spermatozoa to release from supporting Sertoli cells into the lumen of seminiferous tubules" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0001932 ! spermiogenesis

[Term]
id: MT:0004183
name: sympathetic nervous system physiology
namespace: Trait.ontology
def: "anomaly in the function of the part of the autonomic nervous system that innervates smooth muscle, cardiac muscle and glands and mediates the body's response to stressful situations" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0006276 ! autonomic nervous system physiology

[Term]
id: MT:0004184
name: baroreceptor physiology
namespace: Trait.ontology
def: "anomaly in the function of the sensory nerve endings found in the wall of the atria of the heart, vena cava, aortic arch and carotid sinus that are sensitive to changes in blood pressure" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "abnormal baroreflex function" EXACT []
synonym: "abnormal pressoreceptor physiology" EXACT []
is_a: MT:0004183 ! sympathetic nervous system physiology

[Term]
id: MT:0004185
name: adipocyte glucose uptake
namespace: Trait.ontology
is_a: MT:0005666 ! adipose tissue physiology

[Term]
id: MT:0004186
name: area postrema morphology
namespace: Trait.ontology
def: "structural malformation or absence of the small, elevated area in the lateral wall of the inferior recess of the fourth ventricle, involved in the control of cardiorespiratory physiology" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000828 ! fourth ventricle morphology

[Term]
id: MT:0004188
name: timing of embryo turning
namespace: Trait.ontology
def: "completion of axial rotation occurs later than in controls but is eventually completed" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001700 ! embryo turning

[Term]
id: MT:0004189
name: alveolar process
namespace: Trait.ontology
def: "malformation of the thickened ridge of bone that holds the tooth sockets" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal alveolar body" EXACT []
synonym: "abnormal alveolar bone" EXACT []
is_a: MT:0000454 ! jaw morphology

[Term]
id: MT:0004190
name: direction of embryo turning
namespace: Trait.ontology
def: "axial rotation of the embryo in a direction other than the normal anticlockwise direction when viewed towards the caudal pole during the late primitive streak/early somite stage (Mus E8.5-E9.5); clockwise rotation is frequently associated with heart and visceral defects" [The Atlas of Mouse Development:ISBN 0-12-402035-6]
is_a: MT:0001700 ! embryo turning

[Term]
id: MT:0004191
name: neuronal intranuclear inclusions
namespace: Trait.ontology
def: "presence of aggregates of protein within the nuclei of neurons; frequently seen in Huntington's disease" [acv:Alicia Valenzuela_Genetic Resources Curator]
is_a: MT:0002882 ! neuron

[Term]
id: MT:0004192
name: kidney pyramid morphology
namespace: Trait.ontology
def: "malformation of the conical mass of tissue, containing part of the secreting and collecting tubules, whose base faces the renal cortex" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal malpighian pyramid morphology" EXACT []
synonym: "abnormal medullary pyramid morphology" EXACT []
is_a: MT:0003014 ! kidney medulla morphology

[Term]
id: MT:0004193
name: kidney papilla morphology
namespace: Trait.ontology
def: "malformation of the apex of the renal pyramid that projects into a calyx" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0004192 ! kidney pyramid morphology

[Term]
id: MT:0004194
name: kidney pelvis morphology
namespace: Trait.ontology
def: "malformation of the funnel shaped proximal portion of the ureter that is formed by convergence of the major calices" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002135 ! kidney morphology

[Term]
id: MT:0004195
name: calyx morphology
namespace: Trait.ontology
def: "malformation of any of the branches of the renal pelvis that surround each renal papilla and collect urine" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0004194 ! kidney pelvis morphology

[Term]
id: MT:0004196
name: prenatal growth/weight/body size
namespace: Trait.ontology
def: "limited or accelerated growth or development apparent before birth" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0005378 ! growth/size trait

[Term]
id: MT:0004197
name: fetal growth/weight/body size
namespace: Trait.ontology
def: "limited or accelerated growth or development apparent during the fetal period (sensu Mus: from E14 through birth)" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0004196 ! prenatal growth/weight/body size

[Term]
id: MT:0004198
name: fetal size
namespace: Trait.ontology
def: "anomalous proportions of a fetus compared to littermates (sensu Mus: from E14 through birth)" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0004197 ! fetal growth/weight/body size

[Term]
id: MT:0004201
name: fetal growth rate
namespace: Trait.ontology
def: "slow or limited development during the fetal period (sensu Mus: from E14 through birth)" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0004197 ! fetal growth/weight/body size

[Term]
id: MT:0004203
name: cranial flexure morphology
namespace: Trait.ontology
def: "any structural abnormality or absence of the sharp, ventrally concave bend in the developing midbrain of the embryo" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:10730]
synonym: "abnormal cephalic flexure" EXACT []
synonym: "abnormal cerebral flexure" EXACT []
synonym: "abnormal mesencephalic flexure" EXACT []
is_a: MT:0003864 ! midbrain development

[Term]
id: MT:0004204
name: stapes size
namespace: Trait.ontology
def: "lenght, width, or area of the smallest and innermost of the three auditory ossicles" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0003739 ! middle ear ossicle size
is_a: MT:0005107 ! stapes morphology

[Term]
id: MT:0004206
name: dermomyotome development
namespace: Trait.ontology
def: "malformation or absence of the portion of the embryonic somite that remains after migration of the sclerotomic tissue" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:50279]
synonym: "abnormal dermamyotome development" EXACT []
is_a: MT:0000737 ! myotome development

[Term]
id: MT:0004207
name: squamous cell carcinoma
namespace: Trait.ontology
def: "a carcinoma that arises from stratified squamous epithelium that occurs in sites where glandular or columnar epithelium is normally present, such as the skin, esophagus, lungs and cervix" [rbabiuk:Randall Babiuk_Mouse Genome Informatics Curator]
is_a: MT:0002038 ! carcinoma

[Term]
id: MT:0004208
name: basal cell carcinoma
namespace: Trait.ontology
def: "a slow-growing, invasive, but usually non-metastasizing neoplasm that originates from basal keratinocytes in the epidermis" [rbabiuk:Randall Babiuk_Mouse Genome Informatics Curator]
is_a: MT:0002038 ! carcinoma

[Term]
id: MT:0004209
name: sweet taste sensitivity
namespace: Trait.ontology
def: "changes in the ability to perceive a particular flavor or suggestion of something sweet by the chemoreceptors of the gustatory system" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001986 ! taste sensitivity

[Term]
id: MT:0004210
name: bitter taste sensitivity
namespace: Trait.ontology
def: "changes in the ability to perceive a particular flavor or suggestion of something bitter by the chemoreceptors of the gustatory system" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001986 ! taste sensitivity

[Term]
id: MT:0004211
name: sour taste sensitivity
namespace: Trait.ontology
def: "changes in the ability to perceive a particular flavor or suggestion of something sour by the chemoreceptors of the gustatory system" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001986 ! taste sensitivity

[Term]
id: MT:0004212
name: salty taste sensitivity
namespace: Trait.ontology
def: "changes in the ability to perceive a particular flavor or suggestion of something salty by the chemoreceptors of the gustatory system" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001986 ! taste sensitivity

[Term]
id: MT:0004213
name: unami taste sensitivity
namespace: Trait.ontology
def: "changes in the ability to perceive a particular flavor or suggestion of something unami (savory) by the chemoreceptors of the gustatory system" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001986 ! taste sensitivity

[Term]
id: MT:0004214
name: long bone diaphysis morphology
namespace: Trait.ontology
def: "abnormality/malformation of the main or mid section (shaft) of a long bone" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
synonym: "abnormal long bone shaft morphology" EXACT []
is_a: MT:0003723 ! long bone morphology

[Term]
id: MT:0004215
name: myocardial fiber function
namespace: Trait.ontology
def: "function of the multinucleated muscle cells of the heart" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0001544 ! cardiovascular system physiology

[Term]
id: MT:0004218
name: meiotic nondisjunction during M1 phase
namespace: Trait.ontology
def: "abnormal separation of pairs of homologous chromosomes during anaphase of the first meiotic division such that each daughter cell receives one set of paired chromosomes" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001930 ! meiosis

[Term]
id: MT:0004219
name: meiotic nondisjunction during M2 phase
namespace: Trait.ontology
def: "abnormal separation of chromosomes during anaphase of the second meiotic division such that one complete chromosome goes to each daughter cell" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001930 ! meiosis

[Term]
id: MT:0004220
name: peripheral nervous system regeneration
namespace: Trait.ontology
def: "changes in the ability or inability of healthy peripheral nervous system tissue to regenerate following injury or disease" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0004221
name: iridocorneal angle morphology
namespace: Trait.ontology
def: "any structural abnormality of the acute angle occurring between the iris and the cornea at the periphery of the anterior chamber of the eye" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "abnormal angle of the iris" EXACT []
synonym: "abnormal filtration angle" EXACT []
is_a: MT:0005198 ! aqueous drainage system morphology

[Term]
id: MT:0004222
name: synechia
namespace: Trait.ontology
def: "an adhesion of parts, especially involving the iris e.g. attachments of the iris to the trabecular meshwork and peripheral cornea" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "synechiae" EXACT []
is_a: MT:0001322 ! iris morphology

[Term]
id: MT:0004223
name: trabecular meshwork size
namespace: Trait.ontology
def: "reduced size of the pore-like structure surrounding the entire circumference of the anterior chamber through which aqueous humor circulates" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0005203 ! trabecular meshwork morphology

[Term]
id: MT:0004226
name: Schlemm's canal size
namespace: Trait.ontology
def: "length, width, area, or volume of the vascular structure encircling the anterior chamber of the eye, through which the aqueous humor is returned to the blood circulation" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005204 ! canal of Schlemm morphology

[Term]
id: MT:0004228
name: cellular sensitivity to ionizing radiation
namespace: Trait.ontology
def: "level of ionizing radiation needed to induce a specific amount of cell death" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000313 ! cell death

[Term]
id: MT:0004229
name: embryonic erythropoiesis
namespace: Trait.ontology
def: "anomaly in the development of primarily large, nucleated erythroblasts occurring in blood islands in the yolk sac, generally occurs from E7-E11 in the mouse and through 10 weeks in humans" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal primitive erythropoiesis" EXACT []
is_a: MT:0003396 ! embryonic hematopoiesis

[Term]
id: MT:0004230
name: embryonic erythrocyte morphology
namespace: Trait.ontology
def: "structural anomaly of the embryonic blood cells that carry oxygen" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal primitive erythrocyte morphology" EXACT []
is_a: MT:0004229 ! embryonic erythropoiesis

[Term]
id: MT:0004231
name: calcium ion homeostasis
namespace: Trait.ontology
def: "anomaly in the regulation of the levels, transport, and metabolism of calcium ions within the body or between a cell and its external environment" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
comment: not sure if this is the correct GO term; this is a cellular homeostasis term, not a whole-body physiologuiccal term
xref: GO:0006874
is_a: MT:0001765 ! ion homeostasis

[Term]
id: MT:0004233
name: muscle weight
namespace: Trait.ontology
def: "any anomaly in the average muscle weight" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0002269 ! muscle size

[Term]
id: MT:0004234
name: masticatory muscle morphology
namespace: Trait.ontology
def: "anomalous structure of any of the muscles responsible for the movement of the jaws during mastication, including the masseter, temporal, and medial and lateral pterygoid muscles" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000759 ! skeletal muscle morphology

[Term]
id: MT:0004235
name: masseter muscle morphology
namespace: Trait.ontology
def: "anomalous structure of the masticatory muscle of posterior cheek with origin from the inferior border and medial surface of the zygomatic arch, with insertion into the lateral surface of the ramus of the mandible, with nerve supply from the masseteric nerve, and whose action closes the jaw during chewing" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004234 ! masticatory muscle morphology

[Term]
id: MT:0004236
name: masseter muscle size
namespace: Trait.ontology
def: "physical bulk of the masticatory muscle of posterior cheek" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004235 ! masseter muscle morphology

[Term]
id: MT:0004237
name: pterygoid muscle morphology
namespace: Trait.ontology
def: "anomalous structure of the muscles descending from the sphenoid bone to the lower jaw including the internal, or medial, pterygoid muscle and external, or lateral, pterygoid muscle. Action of the former is closing the jaws and that of the latter is opening the jaws, protruding the mandible, and moving the mandible from side to side" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004234 ! masticatory muscle morphology

[Term]
id: MT:0004238
name: pterygoid muscle size
namespace: Trait.ontology
def: "physical bulk of either the internal or external or of both pterygoid muscles" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004237 ! pterygoid muscle morphology

[Term]
id: MT:0004239
name: temporalis muscle morphology
namespace: Trait.ontology
def: "anomalous structure of the superior-most masticatory muscle" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "abnormal musculus temporalis" EXACT []
synonym: "abnormal temporal muscle" EXACT []
synonym: "abnormal temporalis" EXACT []
is_a: MT:0004234 ! masticatory muscle morphology

[Term]
id: MT:0004240
name: temporalis muscle size
namespace: Trait.ontology
def: "length, width, or volume of the superior-most masticatory muscle" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004239 ! temporalis muscle morphology

[Term]
id: MT:0004241
name: acantholysis
namespace: Trait.ontology
def: "separation of prickle cells of the spinous layer of the epidermis, resulting in atrophy of the prickle cell layer, as in conditions such as pemphigus vulgaris and Darier disease" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0001236 ! spinous layer morphology

[Term]
id: MT:0004242
name: plasmacytoid dendritic cell morphology
namespace: Trait.ontology
is_a: MT:0005461 ! dendritic cell morphology/development

[Term]
id: MT:0004243
name: motor nerve terminal sprouting
namespace: Trait.ontology
def: "aberrant response of a motor neuron to form new neuritic processes (sprouts) that emerge from the nodes of Ranvier or terminal arborizations in response to nerve injury (such as denervation), application of nerve toxin, or muscle inactivity (usually due to disease)" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000940 ! motor neuron innervation

[Term]
id: MT:0004244
name: spontaneous abortion
namespace: Trait.ontology
def: "the natural or accidental termination of a pregnancy at a stage where the embryo or the fetus is incapable of surviving independently of the mother" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
subset: slim_cattle
synonym: "miscarriage" EXACT []
is_a: MT:0003699 ! female reproductive system physiology

[Term]
id: MT:0004245
name: genital hemorrhage
namespace: Trait.ontology
def: "bleeding into the genitals" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0003699 ! female reproductive system physiology

[Term]
id: MT:0004246
name: extensor digitorum longus morphology
namespace: Trait.ontology
def: "malformation of penniform muscle of the lateral front part of the leg responsible for extension of the toes and dorsiflexion of the ankle" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal EDL morphology" EXACT []
is_a: MT:0003358 ! hypaxial muscle morphology

[Term]
id: MT:0004248
name: epaxial muscle morphology
namespace: Trait.ontology
def: "malformation of the muscles derived from the medial myotome; includes the intrinsic back muscles" [PMID:1591996]
subset: slim_cattle
subset: slim_pig
is_a: MT:0000759 ! skeletal muscle morphology

[Term]
id: MT:0004249
name: crista ampullaris morphology
namespace: Trait.ontology
def: "form or structure of the elevation found on the inner surface of the ampullae of each semicircular duct; filaments of the vestibular nerve pass through the crista to reach hair cells on its surface; the hair cells are capped by the cupula, a gelatinous protein-polysaccharide mass" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:60193]
synonym: "cristae morphology" EXACT []
is_a: MT:0002428 ! semicircular canal

[Term]
id: MT:0004250
name: tau protein deposits
namespace: Trait.ontology
def: "formation of self-assembled tangles of paired helical filaments and straight filaments due to hyperphosphorylation of the tau protein; often seen in neuronal tissues of individuals with neurodegenerative disorders" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "tau protein tangles" EXACT []
is_a: MT:0002152 ! brain morphology

[Term]
id: MT:0004252
name: heart tube looping direction
namespace: Trait.ontology
def: "orientation of bending during looping morphogenesis" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "cardiac looping direction" RELATED []
relationship: part_of MT:0000269 ! heart tube looping morphogenesis

[Term]
id: MT:0004253
name: atrium appendage integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the small trabeculated chamber projecting  from the atrium proper" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "atrial appendage integrity" RELATED []
relationship: part_of MT:0000024 ! atrium appendage morphology
relationship: part_of MT:0000053 ! heart integrity

[Term]
id: MT:0004254
name: cerebral amyloid angiopathy
namespace: Trait.ontology
def: "a pathological condition where there is a deposition of amyloid in the walls of the small cerebral vessels which supply the brain; this results in an increased risk of infarcts and/or intracerebral hemorrhage, possibly resulting in dementia" [acv:Alicia Valenzuela_Genetic Resources Curator]
is_a: MT:0002152 ! brain morphology

[Term]
id: MT:0004255
name: spongiotrophoblast layer morphology (sensu Rodentia)
namespace: Trait.ontology
def: "anomaly in the structure of the outer structural layer of the rodent placenta" [PMID:11433360]
is_a: MT:0001711 ! placenta morphology

[Term]
id: MT:0004256
name: maternal decidual layer morphology
namespace: Trait.ontology
def: "anomaly in the structure of the maternal uterine-derived portion of the placenta" [PMID:11433360]
is_a: MT:0001711 ! placenta morphology

[Term]
id: MT:0004257
name: placenta weight
namespace: Trait.ontology
def: "any change in a measure of heaviness of the placenta compared to controls" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0004258 ! placenta size

[Term]
id: MT:0004258
name: placenta size
namespace: Trait.ontology
def: "anomaly in the size or shape of the organ of metabolic interchange between fetus and mother" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001711 ! placenta morphology

[Term]
id: MT:0004261
name: embryonic neuroepithelium morphology
namespace: Trait.ontology
def: "structural anomaly in the epithelial cells that line the neural tube and develop into the neurons and glia of the nervous system and into the neural crest cells" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator, Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
is_a: MT:0003861 ! nervous system development

[Term]
id: MT:0004262
name: physical strength
namespace: Trait.ontology
is_a: MT:0002066 ! motor capabilities/coordination/movement

[Term]
id: MT:0004263
name: limb posture
namespace: Trait.ontology
is_a: MT:0001504 ! posture

[Term]
id: MT:0004264
name: extraembryonic tissue physiology
namespace: Trait.ontology
def: "functional anomaly of the membranes involved with embryonic protection and nutrition" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001672 ! embryogenesis/ development

[Term]
id: MT:0004265
name: placental transport
namespace: Trait.ontology
def: "anomaly in the conveyance of metabolic products and nutrients across the placenta" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0004264 ! extraembryonic tissue physiology

[Term]
id: MT:0004266
name: pale placenta
namespace: Trait.ontology
def: "placenta lacking normal reddish coloration, often refers to bloodless condition" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001711 ! placenta morphology

[Term]
id: MT:0004267
name: optic tract morphology
namespace: Trait.ontology
def: "malformation of the band of optic nerve fibers running from the optic chiasma to the lateral geniculate body and midbrain" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0000778 ! tract morphology

[Term]
id: MT:0004268
name: optic stalk morphology
namespace: Trait.ontology
def: "malformation of the narrow, proximal portion of the optic vesicle which connects the embryonic eye and forebrain" [Gray's Anatomy:ISBN 0-914294-08-3]
is_a: MT:0001286 ! eye development

[Term]
id: MT:0004269
name: optic cup morphology
namespace: Trait.ontology
def: "malformation of double walled stuctured formed by expansion and invagination of the distal end of the optic vesicle that develops into the pigmented and sensory layers of the retina while the mouth of the optic cup eventually forms the pupil of the eye" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001286 ! eye development

[Term]
id: MT:0004271
name: paw/hand/foot/hoof morphology
namespace: Trait.ontology
def: "malformation of the pedal or prehensile extremity of vertebrates" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_pig
synonym: "abnormal paw morphology" EXACT []
synonym: "abnormal paws" EXACT []
synonym: "paw abnormalities" RELATED []
is_a: MT:0002109 ! limb morphology

[Term]
id: MT:0004272
name: basement membrane morphology
namespace: Trait.ontology
def: "anomaly in the structure, organization and/or placement of the extracellular supportive tissue adjacent to the basal surface of the epithelia, including the epithelium of muscle cells, fat cells and Schwann cells; it is comprised of type IV collagen, laminin, and sulfated proteoglycans and other components and consists of two layers, the basal lamina and the lamina reticularis" [MeSH:National Library of Medicine_Medical Subject Headings, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
comment: Note: basal lamina and lamina reticularis (or of two basal laminae) compose the basement membrane. thus, in strict sense, the term basement membrane is different from and should not be confused with basal lamina.
synonym: "abnormal basement lamina morphology" EXACT []
is_a: MT:0005395 ! other trait

[Term]
id: MT:0004273
name: basal lamina morphology
namespace: Trait.ontology
def: "anomaly in the structure of the sheet of extracellular matrix characteristically situated under epithelial cells, around muscles, nerves, capillaries, and fat cells, and situated between these elements and the underlying or surrounding connective tissue" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
comment: Note: basal lamina and lamina reticularis (or of two basal laminae) compose the basement membrane. thus, in strict sense, the term basement membrane is different from and should not be confused with basal lamina.
is_a: MT:0004272 ! basement membrane morphology

[Term]
id: MT:0004274
name: embryonic/fetal subventricular zone morphology
namespace: Trait.ontology
synonym: "abnormal embryonic subventricular zone" EXACT []
synonym: "abnormal subventricular zone" BROAD []
synonym: "abnormal SVZ" BROAD []
is_a: MT:0003861 ! nervous system development

[Term]
id: MT:0004275
name: postnatal subventricular zone morphology
namespace: Trait.ontology
synonym: "abnormal subependymal layer" EXACT []
synonym: "abnormal subependymal plate" EXACT []
synonym: "abnormal subependymal zone" EXACT []
synonym: "abnormal subventricular zone" BROAD []
synonym: "abnormal SVZ" BROAD []
is_a: MT:0002152 ! brain morphology

[Term]
id: MT:0004276
name: medial ganglionic eminence morphology
namespace: Trait.ontology
synonym: "abnormal MGE" EXACT []
is_a: MT:0004274 ! embryonic/fetal subventricular zone morphology

[Term]
id: MT:0004277
name: lateral ganglionic eminence morphology
namespace: Trait.ontology
synonym: "abnormal LGE" EXACT []
is_a: MT:0004274 ! embryonic/fetal subventricular zone morphology

[Term]
id: MT:0004278
name: caudal ganglionic eminence morphology
namespace: Trait.ontology
synonym: "abnormal CGE" EXACT []
is_a: MT:0004274 ! embryonic/fetal subventricular zone morphology

[Term]
id: MT:0004279
name: rostral migratory stream morphology
namespace: Trait.ontology
def: "malformation of the transient structure formed by neurons migrating from the subventricular zone into the olfactory bulbs" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006009 ! neuronal migration

[Term]
id: MT:0004280
name: oculomotor nucleus morphology
namespace: Trait.ontology
def: "malformation or disorganization of the group of motor neurons in the floor of the midbrain that gives rise to motor fibers of the oculomotor nerve " [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0000897 ! midbrain morphology

[Term]
id: MT:0004281
name: hypoglossal nucleus morphology
namespace: Trait.ontology
def: "malformation or disorganization of the group of motor neurons throughout most of the length of the medulla oblongata that give rise to the motor fibers of the hypoglossal nerve" [monikat:Monika Tomczuk_Mouse Genome Informatics Curator]
is_a: MT:0000846 ! medulla oblongata

[Term]
id: MT:0004284
name: Descemet membrane morphology
namespace: Trait.ontology
def: "any structural abnormality in the transparent homogeneous acellular layer found between the substantia propria and the endothelial layer of the cornea, considered to be a highly developed basement membrane" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:100136]
synonym: "abnormal Descemet's membrane" EXACT []
synonym: "abnormal Duddell membrane" EXACT []
synonym: "abnormal entocornea" EXACT []
synonym: "abnormal hyaloid membrane" EXACT []
synonym: "abnormal lamina elastica posterior" EXACT []
synonym: "abnormal lamina limitans posterior corneae" EXACT []
synonym: "abnormal membrana hyaloidea" EXACT []
synonym: "abnormal membrana vitrea" EXACT []
synonym: "abnormal posterior elastic layer" EXACT []
synonym: "abnormal posterior limiting lamina of cornea" EXACT []
synonym: "abnormal posterior limiting layer of cornea" EXACT []
synonym: "abnormal tunica vitrea" EXACT []
synonym: "abnormal vitreous membrane" EXACT []
is_a: MT:0001312 ! cornea morphology

[Term]
id: MT:0004286
name: internal auditory canal morphology
namespace: Trait.ontology
def: "form or structure of the canal beginning at the opening of the internal acoustic meatus in the posterior cranial fossa, passing laterally through the petrous portion of the temporal bone to end at the fundus, where a thin plate of bone separates it from the vestibule; it gives passage to the facial and vestibulocochlear nerves together with the labyrinthine artery and veins" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "internal acoustic meatus morphology" EXACT []
synonym: "internal auditory meatus morphology" EXACT []
synonym: "meatus auditorius internus morphology" EXACT []
is_a: MT:0000026 ! inner ear morphology

[Term]
id: MT:0004287
name: spiral limbus morphology
namespace: Trait.ontology
def: "form or structure of the border of the spiral lamina, i.e. the thickened periosteum covering the upper plate of the bony spiral lamina of the cochlea" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "limbus laminae spiralis osseae morphology" EXACT []
synonym: "limbus spiralis morphology" EXACT []
is_a: MT:0000031 ! cochlea morphology

[Term]
id: MT:0004288
name: spiral ligament morphology
namespace: Trait.ontology
def: "form or structure of the thickened periosteal lining of the bony cochlea that forms the outer wall of the cochlear duct to which the basal lamina attaches" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "crista spiralis morphology" EXACT []
synonym: "ligamentum spirale cochleae morphology" EXACT []
synonym: "ligamentum spirale ductus cochlearis morphology" EXACT []
synonym: "spiral crest morphology" EXACT []
synonym: "spiral ligament of cochlea morphology" EXACT []
synonym: "spiral ligament of cochlear duct morphology" EXACT []
is_a: MT:0003169 ! scala media morphology

[Term]
id: MT:0004289
name: bony labyrinth morphology
namespace: Trait.ontology
def: "any structural abnormality in the series of cavities (cochlea, vestibule, and semicircular canals) contained within the otic capsule of the petrous portion of the temporal bone; the bony labyrinth is filled with perilymph, in which the delicate, endolymph-filled membranous labyrinth is suspended" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "abnormal labyrinthus osseus" EXACT []
synonym: "abnormal osseous labyrinth" EXACT []
is_a: MT:0000026 ! inner ear morphology

[Term]
id: MT:0004290
name: stapes footplate morphology
namespace: Trait.ontology
def: "form or structure of the flat portion of the stapes that fits in the oval window" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "base of stapes" EXACT []
synonym: "basis stapedis morphology" EXACT []
is_a: MT:0005107 ! stapes morphology

[Term]
id: MT:0004291
name: conductive hearing function
namespace: Trait.ontology
def: "sound conduction through the middle-ear apparatus e.g. velocity transfer responses at the umbo or incus level during sound stimulation of the tympanic membrane" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "middle-ear sound conduction" RELATED []
is_a: MT:0001963 ! hearing

[Term]
id: MT:0004292
name: spiral ligament fibrocyte morphology
namespace: Trait.ontology
def: "form or structure of any of the four types of fibrocytes (types I, II , III and IV) that constitute the spiral ligament" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004288 ! spiral ligament morphology

[Term]
id: MT:0004293
name: type I spiral ligament fibrocyte morphology
namespace: Trait.ontology
def: "form or structure of type I spiral ligament fibrocytes which occupy the region beneath the stria vascularis" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004292 ! spiral ligament fibrocyte morphology

[Term]
id: MT:0004294
name: type II spiral ligament fibrocytes morphology
namespace: Trait.ontology
def: "form or structure of type II spiral ligament fibrocytes found in the suprastrial zone and the central area of the spiral ligament beneath the spiral prominence" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004292 ! spiral ligament fibrocyte morphology

[Term]
id: MT:0004295
name: type III spiral ligament fibrocyte morphology
namespace: Trait.ontology
def: "form or structure of type III spiral ligament fibrocytes which form a cell layer attached to the otic capsule" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004292 ! spiral ligament fibrocyte morphology

[Term]
id: MT:0004296
name: type IV spiral ligament fibrocyte morphology
namespace: Trait.ontology
def: "form or structure of type IV spiral ligament fibrocytes found in the triangular space inferior to the basilar crest" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004292 ! spiral ligament fibrocyte morphology

[Term]
id: MT:0004297
name: proprioceptive neuron morphology
namespace: Trait.ontology
def: "anomaly in the sensory neurons of the dorsal root ganglia that sense body position and send information about how much the muscle is stretched to the spinal cord" [hdene:Howard Dene_Mouse Genome Informatics Curator]
is_a: MT:0000965 ! sensory neuron morphology
is_a: MT:0002882 ! neuron

[Term]
id: MT:0004298
name: vestibular ganglion integrity
namespace: Trait.ontology
def: "loss of the group of bipolar sensory nerve cell bodies concerned with equilibration that form a swelling on the vestibular part of the eighth cranial nerve in the fundus of the internal acoustic meatus " [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "degeneration of ganglion vestibulare " EXACT []
synonym: "degeneration of Scarpa ganglion" EXACT []
is_a: MT:0002856 ! vestibular ganglion morphology

[Term]
id: MT:0004300
name: organ of Corti supporting cell morphology
namespace: Trait.ontology
def: "form, structure, or number of the highly differentiated epithelial cells with distinctive morphological features surrounding the hair cells in the organ of Corti; inner hair cells (IHCs) are normally surrounded by (inner and outer) phalangeal cells while OHCs are in contact with Deiters and pillar cells; Hensen cells are positioned further laterally in the organ of Corti" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000042 ! organ of Corti

[Term]
id: MT:0004302
name: Dieters cell morphology
namespace: Trait.ontology
def: "form, structure or number of the supporting cells of the spiral organ which are attached to the basement membrane and receive the hair cells between their free extremities" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "abnormal phalangeal cell morphology" EXACT []
is_a: MT:0004300 ! organ of Corti supporting cell morphology

[Term]
id: MT:0004303
name: Hensen cell morphology
namespace: Trait.ontology
def: "form, structure or number of the supporting cells that form the lateral border of the organ of Corti, immediately to the outer side of Deiters' cells " [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004300 ! organ of Corti supporting cell morphology

[Term]
id: MT:0004305
name: Rosenthal canal morphology
namespace: Trait.ontology
def: "form or structure of the winding tube of the bony labyrinth that makes two and a half turns about the modiolus of the cochlea; it is divided incompletely into two compartments by a winding shelf of bone, the bony spiral lamina" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "canalis spiralis cochleae morphology" EXACT []
synonym: "cochlear canal morphology" EXACT []
is_a: MT:0000031 ! cochlea morphology
is_a: MT:0002729 ! canal morphology

[Term]
id: MT:0004306
name: Rosenthal canal size
namespace: Trait.ontology
def: "reduced size of the winding tube of the bony labyrinth that makes two and a half turns about the modiolus of the cochlea" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "small canalis spiralis cochleae" EXACT []
synonym: "small cochlear canal" EXACT []
is_a: MT:0004305 ! Rosenthal canal morphology

[Term]
id: MT:0004308
name: basilar membrane morphology
namespace: Trait.ontology
def: "form or structure of the membrane extending from the bony spiral membrane to the basilar crest of the cochlea; it forms the greater part of the floor of the cochlear duct separating the latter from the scala tympani, and it supports the organ of Corti" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "basilar lamina morphology" EXACT []
synonym: "lamina basilaris cochleae morphology" EXACT []
synonym: "lamina basilaris ductus cochlearis morphology" EXACT []
synonym: "membrana basilaris morphology" EXACT []
synonym: "morphology of the basilar membrane of cochlear duct" EXACT []
is_a: MT:0000031 ! cochlea morphology

[Term]
id: MT:0004310
name: otic vesicle size
namespace: Trait.ontology
def: "area or volume of the simple epithelial sac formed from the otic placode that gives rise to the structures of the inner ear" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "otocyst size" EXACT []
is_a: MT:0006030 ! otic vesicle formation

[Term]
id: MT:0004311
name: otic vesicle cell number
namespace: Trait.ontology
def: "number of cells in the simple epithelial sac formed from the otic placode that gives rise to the structures of the inner ear" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0006030 ! otic vesicle formation

[Term]
id: MT:0004313
name: vestibulocochlear ganglion size
namespace: Trait.ontology
def: "area of the group of neuron cell bodies associated with the eighth cranial nerve during embryogenesis; splits in later development to form the cochlear and vestibular ganglia" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0003703 ! vestibulocochlear ganglion morphology

[Term]
id: MT:0004316
name: saccule size
namespace: Trait.ontology
def: "length, width, area, or volume of the cavity between the semicircular canals and the cochlea of the inner ear" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0006089 ! saccule morphology

[Term]
id: MT:0004320
name: sternum shape
namespace: Trait.ontology
def: "appearance of the long flat bone of the chest which articulates with clavicle and first seven rib pairs" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000157 ! sternum morphology

[Term]
id: MT:0004321
name: sternum length
namespace: Trait.ontology
def: "reduced length of the long flat bone of the chest which articulates with clavicle and first seven rib pairs" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0004323 ! sternum size

[Term]
id: MT:0004322
name: sternebra morphology
namespace: Trait.ontology
def: "malformation of one segments of the primordial sternum of the embryo; these segments fuse to form the body of the adult vertebrate sternum" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal sternebrae morphology" EXACT []
is_a: MT:0000157 ! sternum morphology
is_a: MT:0002113 ! skeleton development

[Term]
id: MT:0004323
name: sternum size
namespace: Trait.ontology
def: "reduced size of the sternum due to decreased cell number" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000157 ! sternum morphology

[Term]
id: MT:0004324
name: vestibular hair cell integrity
namespace: Trait.ontology
def: "susceptibility of the vestibular hairs to loss or degeneration" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0002623 ! vestibular hair cell morphology

[Term]
id: MT:0004326
name: vestibular hair cell number
namespace: Trait.ontology
def: "number of cells in the sensory epithelium of the maculae and cristae of the membranous labyrinth of the internal ear" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0002623 ! vestibular hair cell morphology

[Term]
id: MT:0004329
name: saccular integrity
namespace: Trait.ontology
def: "susceptibility of the smaller of the two sacs in the vestibule to loss or degeneration" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0006089 ! saccule morphology

[Term]
id: MT:0004330
name: saccular macula morphology
namespace: Trait.ontology
def: "structure or form of the oval neuroepithelial sensory receptor in the anterior wall of the saccule; hair cells of the neuroepithelium support the statoconial membrane and have terminal arborizations of vestibular nerve fibers around their bodies" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "macula sacculi morphology" EXACT []
synonym: "saccular spot morphology " RELATED []
is_a: MT:0006089 ! saccule morphology

[Term]
id: MT:0004331
name: saccular macula integrity
namespace: Trait.ontology
def: "susceptibility of the oval neuroepithelial sensory receptor in the anterior wall of the saccule to degeneration or loss" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004330 ! saccular macula morphology

[Term]
id: MT:0004332
name: utricular integrity
namespace: Trait.ontology
def: "susceptibility of the larger of the two sacs in the vestibule to degeneration or loss" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0006090 ! utricle morphology

[Term]
id: MT:0004333
name: utricular macula morphology
namespace: Trait.ontology
def: "structure or form of the neuroepithelial sensory receptor in the inferolateral wall of the utricle; hair cells of the neuroepithelium support the statoconial membrane and have terminal arborizations of vestibular nerve fibers around their bodies; normally sensitive to linear acceleration in the longitudinal axis of the body and to gravitational influences" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "macula utriculi morphology" EXACT []
synonym: "utricular spot morphology" EXACT []
is_a: MT:0006090 ! utricle morphology

[Term]
id: MT:0004334
name: utricular macular integrity
namespace: Trait.ontology
def: "susceptibility of the neuroepithelial sensory receptor in the inferolateral wall of the utricle to loss or degeneration" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004333 ! utricular macula morphology

[Term]
id: MT:0004335
name: utricle size
namespace: Trait.ontology
def: "length, width, area, or volume of the larger of the two sacs in the vestibule" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0006090 ! utricle morphology

[Term]
id: MT:0004337
name: clavicle cell number
namespace: Trait.ontology
def: "reduced cell number resulting in reduced size of one or both of the doubly curved long bone that forms part of the shoulder girdle and articulates with the sternum and the scapula" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "hypoplastic clavicles" EXACT []
is_a: MT:0004338 ! clavicle size

[Term]
id: MT:0004338
name: clavicle size
namespace: Trait.ontology
def: "reduced size of one or both of the doubly curved long bone that forms part of the shoulder girdle and articulates with the sternum and the scapula" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005298 ! clavicle morphology

[Term]
id: MT:0004340
name: scapula length
namespace: Trait.ontology
def: "reduced length of of either or both of the large, flat bones of the back part of the shoulder" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0004343 ! scapula size

[Term]
id: MT:0004342
name: scapular bone foramen
namespace: Trait.ontology
def: "presence of a hole in either or both of the large, flat bones of the back part of the shoulder" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "hole in scapula" EXACT []
synonym: "scapula foramen" EXACT []
synonym: "scapula hole" EXACT []
synonym: "scapular hole" EXACT []
is_a: MT:0000149 ! scapula morphology

[Term]
id: MT:0004343
name: scapula size
namespace: Trait.ontology
def: "reduced size of either or both of the large, flat bones of the back part of the shoulder" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000149 ! scapula morphology

[Term]
id: MT:0004344
name: scapular bone cell number
namespace: Trait.ontology
def: "reduced bone cell number in either or both of the large, flat bones of the back part of the shoulder" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0004343 ! scapula size

[Term]
id: MT:0004345
name: acromion morphology
namespace: Trait.ontology
def: "any structural anomaly of the lateral end of the spine of the scapula which projects as a broad flattened process and articulates with the clavicle, and forms the point of the shoulder" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal acromial process morphology" EXACT []
is_a: MT:0000149 ! scapula morphology

[Term]
id: MT:0004347
name: scapular spine morphology
namespace: Trait.ontology
def: "any structural anomaly of the trianguar ridge on the dorsal aspect of the scapula which separates the supra- from the infraspinatous fossa and where the trapezius and deltoid muscles are attached " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal spine of scapula" EXACT []
is_a: MT:0000149 ! scapula morphology

[Term]
id: MT:0004348
name: femur length
namespace: Trait.ontology
def: "increased length of the long bone of the thigh" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: ID:0000369 ! femur dimensions

[Term]
id: MT:0004350
name: humerus length
namespace: Trait.ontology
def: "increased length of one or both of the bones of the forelimb that articulates with the scapula above and the radius and ulna below" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
is_a: MT:0005296 ! humerus morphology

[Term]
id: MT:0004353
name: deltoid tuberosity morphology
namespace: Trait.ontology
def: "any structural anomaly of a rough elevation at the middle of the lateral side of the shaft of the humerus to which the the deltoid muscle attaches" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal deltoid crest" EXACT []
synonym: "abnormal deltoid eminence" EXACT []
synonym: "abnormal deltoid impression" EXACT []
synonym: "abnormal deltoid process" EXACT []
is_a: MT:0005296 ! humerus morphology

[Term]
id: MT:0004355
name: radius length
namespace: Trait.ontology
def: "reduced length of the short bone of the lateral forearm" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000552 ! radius morphology

[Term]
id: MT:0004356
name: radius cell number
namespace: Trait.ontology
def: "reduced cell number in the short bone of the lateral forearm resulting in decreased size" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000552 ! radius morphology

[Term]
id: MT:0004357
name: tibia length
namespace: Trait.ontology
def: "increased length of the medial and larger of the two bones of the lower leg" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
is_a: MT:0000558 ! tibia morphology

[Term]
id: MT:0004358
name: tibia curvature
namespace: Trait.ontology
def: "curvature of the medial and larger of the two bones of the lower leg" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "bent tibia" EXACT []
is_a: MT:0000558 ! tibia morphology

[Term]
id: MT:0004361
name: ulna curvature
namespace: Trait.ontology
def: "curvature of the medial and larger of the two bones of the forearm" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "bent ulna" EXACT []
is_a: MT:0005108 ! ulna morphology

[Term]
id: MT:0004362
name: cochlear hair cell integrity
namespace: Trait.ontology
def: "susceptipility of the sensory epithelial cells of the cochlea; these cells are in synaptic contact with the auditory nerve to degeneration or loss" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002622 ! cochlear hair cell morphology

[Term]
id: MT:0004363
name: stria vascularis integrity
namespace: Trait.ontology
def: "susceptibility of the stria vascularis to degeneration or loss" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000048 ! stria vascularis morphology

[Term]
id: MT:0004364
name: stria vascularis size
namespace: Trait.ontology
def: "length, width, or area of the stria vascularis" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000048 ! stria vascularis morphology

[Term]
id: MT:0004365
name: strial basal cell morphology
namespace: Trait.ontology
def: "form or structure of the polarized cells which are juxtaposed to fibrocytes in the underlying spiral ligament" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000048 ! stria vascularis morphology

[Term]
id: MT:0004366
name: strial marginal cell morphology
namespace: Trait.ontology
def: "form or structure of the polarized columnar cells of epithelial origin which cover the lateral surface of the cochlear duct, secrete K+ and form a continuous sheet in contact with the endolymph; marginal cells form extensive interdigitations with the basal and intermediate cells in the normal adult stria" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000048 ! stria vascularis morphology

[Term]
id: MT:0004367
name: strial intermediate cell morphology
namespace: Trait.ontology
def: "form or structure of the melanocytes known to migrate from the neural crest during ontogeny to become located between the epithelial marginal cell layer and the mesodermal basal cell layer within the intrastrial space; the predominant cellular component of the electrogenic machinery that generates an endocochlear potential (80-100 mV)" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "cochlear melanocyte morphology" EXACT []
synonym: "stria vascularis intermediate cell morphology" EXACT []
synonym: "stria vascularis melanocyte morphology" RELATED []
synonym: "strial melanocyte morphology" EXACT []
is_a: MT:0000048 ! stria vascularis morphology
is_a: MT:0002877 ! melanocyte morphology

[Term]
id: MT:0004368
name: stria vascularis blood vessel morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the blood vessels supplying the stria vascularis in the cochlea of the inner ear" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "morphology of the stria vascularis vasculature" EXACT []
synonym: "strial vascular morphology" EXACT []
xref: MP:0004368
is_a: MT:0000048 ! stria vascularis morphology
is_a: MT:0001614 ! blood vessel morphology

[Term]
id: MT:0004370
name: ulna length
namespace: Trait.ontology
def: "increased length of the medial and larger of the two bones of the forearm" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005108 ! ulna morphology

[Term]
id: MT:0004371
name: femur curvature
namespace: Trait.ontology
def: "curvature of the long bone of the thigh" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "bent femur" EXACT []
is_a: MT:0000559 ! femur morphology

[Term]
id: MT:0004372
name: fibula curvature
namespace: Trait.ontology
def: "curvature of the lateral and smaller bone of the lower limb" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "bent fibula" EXACT []
is_a: MT:0002187 ! fibula morphology

[Term]
id: MT:0004373
name: humerus curvature
namespace: Trait.ontology
def: "curvature of the bone of the forelimb that articulates with the scapula above and the radius and ulna below" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "bent humerus" EXACT []
is_a: MT:0005296 ! humerus morphology

[Term]
id: MT:0004374
name: radius curvature
namespace: Trait.ontology
def: "curvature of the short bone of the lateral forearm" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000552 ! radius morphology

[Term]
id: MT:0004381
name: hair follicle melanocyte morphology
namespace: Trait.ontology
def: "any structural anomaly of the cells that produce pigment in the hair follicles" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0002075 ! coat color
is_a: MT:0002877 ! melanocyte morphology

[Term]
id: MT:0004382
name: hair follicle melanogenesis
namespace: Trait.ontology
def: "failure of or anomaly in the biosynthetic pathway of melanin formation in hair follicles" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0002075 ! coat color
is_a: MT:0005077 ! melanogenesis

[Term]
id: MT:0004387
name: prechordal plate morphology
namespace: Trait.ontology
def: "any structural anomaly of the horseshoe-shaped thickening of the endoderm at the cranial (rostral) end of the primitive streak formed by the involution of Spemann's organizer cells which, together with the notochord, induces the formation of the neural plate from the overlying ectodermal cells and contributes mesodermal type cells to the surrounding tissue" [Principles of Neural Science_3rd edition:ISBN 0-8385-8034-3]
synonym: "abnormal prochordal plate morphology" EXACT []
is_a: MT:0002084 ! developmental patterning

[Term]
id: MT:0004389
name: respiratory bronchiole morphology
namespace: Trait.ontology
def: "any structural anomaly of the smallest bronchioles, which connect the terminal bronchioles to alveolar ducts and have alveoli rising from their walls" [brs:Beverly Richards-Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002267 ! bronchiole morphology

[Term]
id: MT:0004390
name: bronchoalveolar duct junction morphology
namespace: Trait.ontology
def: "any structural anomaly of the branch point connecting the respiratory bronchioles to the alveolar ducts" [brs:Beverly Richards-Smith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002271 ! respiratory alveolar duct morphology
is_a: MT:0004389 ! respiratory bronchiole morphology

[Term]
id: MT:0004391
name: respiratory conducting tube
namespace: Trait.ontology
def: "any structural anomaly of the tubes of the respiratory system that allows passage of air from the trachea to the alveoli of the lungs" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal respiratory passage" EXACT []
is_a: MT:0001175 ! lung morphology

[Term]
id: MT:0004392
name: CD8+ T cell physiology
namespace: Trait.ontology
def: "anomalous response of the subset of T lymphocytes that carry the CD8 marker" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
subset: slim_pig
is_a: MT:0002444 ! T cell physiology

[Term]
id: MT:0004393
name: cochlear inner hair cell morphology
namespace: Trait.ontology
def: "structure or form of the sensory cells of the organ of Corti which are in synaptic contact with sensory as well as efferent fibers of the auditory nerve; there is a single row of flask-shaped inner hair cells tightly surrounded by supporting interphalangeal cells; the apical end of each cell is anchored to the cuticular plate and about 100 stereocilia arranged in a more or less linear (or shallow) U-shaped pattern extend from the cell's surface through the cuticular plate into the endolymphic space inferior to the tectorial membrane" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "cochlear IHC morphology" EXACT []
is_a: MT:0002622 ! cochlear hair cell morphology

[Term]
id: MT:0004394
name: cochlear inner hair cell number
namespace: Trait.ontology
def: "number of the flask-shaped inner hair sensory cells of the organ of Corti which are in synaptic contact with sensory as well as efferent fibers of the auditory nerve" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004393 ! cochlear inner hair cell morphology
is_a: MT:0004406 ! cochlear hair cell number

[Term]
id: MT:0004398
name: cochlear inner hair cell integrity
namespace: Trait.ontology
def: "susceptibility of the single row of flask-shaped inner hair sensory cells of the organ of Corti to degeneration or loss" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004362 ! cochlear hair cell integrity
is_a: MT:0004393 ! cochlear inner hair cell morphology

[Term]
id: MT:0004399
name: cochlear outer hair cell morphology
namespace: Trait.ontology
def: "structure or form of the sensory cells of the organ of Corti which are in synaptic contact with sensory as well as efferent fibers of the auditory nerve; there are three rows of columnar outer hair cells largely surrounded by cortilymph and supporting phalangeal cells; the apical end of each cell is anchored to the cuticular plate and about 100 stereocilia arranged in a V-shaped pattern extend from the cell's surface through the cuticular plate into the tectorial membrane" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "cochlear OHC morphology" EXACT []
is_a: MT:0002622 ! cochlear hair cell morphology

[Term]
id: MT:0004400
name: cochlear outer hair cell number
namespace: Trait.ontology
def: "number of the columnar outer hair sensory cells of the organ of Corti" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004399 ! cochlear outer hair cell morphology
is_a: MT:0004406 ! cochlear hair cell number

[Term]
id: MT:0004404
name: cochlear outer hair cell integrity
namespace: Trait.ontology
def: "susceptibility of the columnar outer hair sensory cells of the organ of Corti to degeneration or loss" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004362 ! cochlear hair cell integrity
is_a: MT:0004399 ! cochlear outer hair cell morphology

[Term]
id: MT:0004406
name: cochlear hair cell number
namespace: Trait.ontology
def: "number of the sensory epithelial cells of the cochlea, which are normally in synaptic contact with the auditory nerve" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0002622 ! cochlear hair cell morphology

[Term]
id: MT:0004409
name: ampullary crest neuroepithelium morphology
namespace: Trait.ontology
def: "shape or structure of the specialized sensory hair cells of the ampullary crest of the ampulla of each semicircular duct" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004249 ! crista ampullaris morphology

[Term]
id: MT:0004412
name: cochlear potential
namespace: Trait.ontology
def: "bioelectric potentials produced by the hair cells of the organ of Corti in response to sound; cochlear microphonics faithfully represent the frequency and intensity of the acoustic stimulation" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "abnormal cochlear microphonic(s)" EXACT []
is_a: MT:0000365 ! hearing electrophysiology
is_a: MT:0000483 ! sensorineural hearing function

[Term]
id: MT:0004415
name: cochlear nerve compound action potential
namespace: Trait.ontology
def: "the combined potentials resulting from activation of the auditory division of the eighth cranial nerve" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "auditory nerve compound action potential" RELATED []
is_a: MT:0000365 ! hearing electrophysiology
is_a: MT:0000483 ! sensorineural hearing function
is_a: MT:0005402 ! action potential

[Term]
id: MT:0004423
name: squamosal bone morphology
namespace: Trait.ontology
def: "any structural anomaly of the thin, platelike part of the temporal bone" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0005272 ! temporal bone morphology

[Term]
id: MT:0004425
name: otolith organ morphology
namespace: Trait.ontology
def: "form or structure of the utricle and saccule of the inner ear which possess otoliths and respond to linear acceleration and deceleration, including gravity" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000034 ! vestibule morphology

[Term]
id: MT:0004426
name: cochlear labyrinth morphology
namespace: Trait.ontology
def: "form or structure of the portion of the membranous labyrinth concerned with the sense of hearing (vs. the vestibular labyrinth, which is concerned with the sense of equilibration) and innervated by the cochlear nerve; it is located within the cochlea of the bony labyrinth, and consists of the cochlear duct, which contains the spiral organ " [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "labyrinthus cochlearis morphology" EXACT []
synonym: "organ of hearing morphology" EXACT []
is_a: MT:0000035 ! membranous labyrinth

[Term]
id: MT:0004427
name: vestibular labyrinth morphology
namespace: Trait.ontology
def: "form or structure of the portion of the membranous labyrinth concerned with the sense of equilibration (vs. the cochlear labyrinth, which is concerned with the sense of hearing) and innervated by the vestibular nerve; it is located within the semicircular canals and vestibule of the bony labyrinth, and consists of the utricle, saccule, and the semicircular, utriculosaccular, and endolymphatic ducts " [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "labyrinthus vestibularis morphology" EXACT []
synonym: "vestibular organ morphology" EXACT []
is_a: MT:0000035 ! membranous labyrinth

[Term]
id: MT:0004428
name: type I vestibular cell morphology
namespace: Trait.ontology
def: "form, structure, number or organization of the flask-shaped sensory cells of the maculae and cristae of the vestibular labyrinth of the inner ear, which are normally enclosed in calyx endings of afferent neurons; afferent and efferent nerve fibers of the vestibular nerve synapse with them; from the apical end of each cell a bundle of stereocilia and a kinocilium extend into the otolithic membrane of the maculae or the cupula of the cristae " [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0002623 ! vestibular hair cell morphology

[Term]
id: MT:0004429
name: type II vestibular cell morphology
namespace: Trait.ontology
def: "form, structure, number or organization of the cylindrical sensory cells of the maculae and cristae of the vestibular labyrinth of the inner ear which are normally contacted by bouton endings of afferent and efferent neurons; afferent and efferent nerve fibers of the vestibular nerve synapse with them; from the apical end of each cell a bundle of stereocilia and a kinocilium extend into the otolithic membrane of the maculae or the cupula of the cristae" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0002623 ! vestibular hair cell morphology

[Term]
id: MT:0004430
name: Claudius cell morphology
namespace: Trait.ontology
def: "form or structure of the columnar cells located on the floor of the ductus cochlearis external to the spiral organ" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0003169 ! scala media morphology

[Term]
id: MT:0004431
name: hair cell mechanoelectric transduction
namespace: Trait.ontology
def: "conversion of mechanical energy into electric(al) energy by sensory cells, such as auditory and vestibular hair cells, required for auditory sensation" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0003879 ! hair cell physiology

[Term]
id: MT:0004432
name: cochlear hair cell physiology
namespace: Trait.ontology
def: "processes pertinent to the integrated function of cochlear hair cells i.e. the sensory cells in the spiral organ which are in synaptic contact with sensory as well as efferent fibers of the cochlear (auditory) nerve " [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0003879 ! hair cell physiology

[Term]
id: MT:0004433
name: cochlear inner hair cell physiology
namespace: Trait.ontology
def: "processes pertinent to the function of cochlear IHCs which constitute the true sensory cell type sending impulses via the cochlear (auditory) nerve" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "abnormal cochlear IHC physiology" EXACT []
is_a: MT:0004432 ! cochlear hair cell physiology

[Term]
id: MT:0004434
name: cochlear outer hair cell physiology
namespace: Trait.ontology
def: "processes pertinent to the function of cochlear OHCs which are known to enhance the performance of the cochlea, both qualitatively (increased selectivity) and quantitatively (increased sensitivity); in addition to the mechanoelectric transduction required for auditory sensation, OHCs also perform electromechanical transduction, whereby transmembrane voltage drives rapid changes in the length and stiffness of OHCs at audio frequencies in vitro (electromotility)" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "abnormal cochlear OHC physiology" EXACT []
is_a: MT:0004432 ! cochlear hair cell physiology

[Term]
id: MT:0004435
name: cochlear outer hair cell electromotility
namespace: Trait.ontology
def: "motility of the cochlear OHCs in response to electrical stimulation; normally, the motile response (i.e. rapid change in length and stiffness of OHCs) is closely coupled to the changing transduction current and provides a region-specific amplification in the movement of the spiral organ that enhances transduction at the IHCs in that specific region of the cochlear spiral, increasing both sensitivity and specificity; electromotility is believed to arise through voltage-gated conformational changes in motor protein (prestin) or proteins located in the lateral wall of the OHC" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
synonym: "abnormal electromechanical transduction" EXACT []
synonym: "abnormal OHC electromotility" EXACT []
is_a: MT:0004434 ! cochlear outer hair cell physiology

[Term]
id: MT:0004438
name: vestibular hair cell physiology
namespace: Trait.ontology
def: "processes pertinent to the integrated function of the sensory epithelium of the maculae and cristae in the membranous labyrinth of the inner ear" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0003879 ! hair cell physiology

[Term]
id: MT:0004442
name: occipital bone foramen
namespace: Trait.ontology
def: "presence of a hole in the bone at the lower, posterior part of the skull" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "hole in occipital bone" EXACT []
synonym: "occipital bone hole" EXACT []
is_a: MT:0005269 ! occipital bone morphology

[Term]
id: MT:0004446
name: split exoccipital bone
namespace: Trait.ontology
def: "the appearance of a division in the bone or region on the lateral sides of the great foremen of the skull, which often forms a part of the occipital in the adult, but is usually distinct in the young" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000080 ! exoccipital bone morphology

[Term]
id: MT:0004448
name: presphenoid bone morphology
namespace: Trait.ontology
def: "any structural anomaly of the anterior part of the body of the sphenoid bone in front of the basisphenoid; it is usually a separate bone in the young or fetus, but becomes a part of the sphenoid in the adult" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000104 ! sphenoid bone morphology

[Term]
id: MT:0004452
name: pterygoid process morphology
namespace: Trait.ontology
def: "any structural anomaly of the process projecting downward from either side of the sphenoid bone, in vertebrates divided into two plates, an inner and an outer (sometimes called the lateral and medial); the posterior nares pass through the space, called the pterygoid fossa, between the processes" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000104 ! sphenoid bone morphology

[Term]
id: MT:0004453
name: pterygoid bone morphology
namespace: Trait.ontology
def: "any structural anomaly of the bone region which corresponds to the inner plate of the pterygoid process of the mammalian skull" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0004452 ! pterygoid process morphology

[Term]
id: MT:0004457
name: orbitosphenoid bone morphology
namespace: Trait.ontology
def: "any structural anomaly of the bone that is situated in the orbit on either side of the presphenoid; it generally forms a part of the sphenoid in the adult, and may be independent in the young" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000104 ! sphenoid bone morphology

[Term]
id: MT:0004463
name: basisphenoid bone foramen
namespace: Trait.ontology
def: "the presence of one or more holes in part of the base of the cranium between the basioccipital and the presphenoid, which usually ossifies separately in the embryo or in the young, and becomes a part of the sphenoid in the adult; in many animals it persists as a separate bone between the basioccipital bone and the presphenoidal bone" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "basisphenoid bone hole" EXACT []
synonym: "hole in basisphenoid bone" EXACT []
is_a: MT:0000106 ! basisphenoid bone morphology

[Term]
id: MT:0004465
name: integrity of the supporting cells of the organ of Corti
namespace: Trait.ontology
def: "degeneration or loss of the highly differentiated epithelial cells with distinctive morphological features that surround all hair cells in the organ of Corti" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004300 ! organ of Corti supporting cell morphology

[Term]
id: MT:0004466
name: cochlear outer hair cell length
namespace: Trait.ontology
def: "distance from tip to root of the cochlear outer hair cells" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0004399 ! cochlear outer hair cell morphology

[Term]
id: MT:0004469
name: zygomatic arch morphology
namespace: Trait.ontology
def: "any structural anomaly of the the bony arch in vertebrates that extends along the side or front of the skull beneath the eye socket and is formed by the temporal process of the zygomatic bone and the zygomatic process of the temporal bone" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal malar arch morphology" EXACT []
synonym: "abnormal zygoma morphology" EXACT []
is_a: MT:0005270 ! zygomatic bone morphology
is_a: MT:0005272 ! temporal bone morphology

[Term]
id: MT:0004478
name: testicular teratoma
namespace: Trait.ontology
def: "neoplasms found in the testis that are composed of multiple tissue types; includes types not normally found in tesis" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002627 ! teratoma
is_a: MT:0006262 ! testis tumor

[Term]
id: MT:0004479
name: oval window morphology
namespace: Trait.ontology
def: "structure or form of the oval opening on the medial wall of the tympanic cavity leading into the vestibule, close to the foot of the stapes" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "fenestra ovalis morphology" EXACT []
synonym: "fenestra vestibuli morphology" EXACT []
synonym: "morphology of the fenestra of the vestibule" EXACT []
synonym: "vestibular window morphology" EXACT []
is_a: MT:0000049 ! middle ear morphology

[Term]
id: MT:0004480
name: round window morphology
namespace: Trait.ontology
def: "structure or form of the opening on the medial wall of the middle ear leading into the cochlea, closed in life by the secondary tympanic membrane; serves to regulate fluid pressure in the inner ear" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "cochlear window morphology" EXACT []
synonym: "fenestra cochleae morphology" EXACT []
synonym: "fenestra rotunda morphology" EXACT []
synonym: "morphology of the fenestra of the cochlea" EXACT []
is_a: MT:0000049 ! middle ear morphology

[Term]
id: MT:0004481
name: conjunctival epithelium morphology
namespace: Trait.ontology
def: "any structural anomaly in the conjunctival layer of epithelial cells covering inner surface of the eyelid and the front of the eyeball except over the cornea" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001310 ! conjunctiva morphology

[Term]
id: MT:0004482
name: interdental cell morphology
namespace: Trait.ontology
def: "form, structure, or number of the long, spindle-shaped cells arranged in parallel rows, oriented with their vertical axis perpendicular to the luminal surface of the spiral limbus; they secrete K+ into the endolymph and secrete the tectoral membrane" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0004287 ! spiral limbus morphology

[Term]
id: MT:0004487
name: type I spiral ligament fibrocyte integrity
namespace: Trait.ontology
def: "susceptibility of type I spiral ligament fibrocytes to degeneration or loss" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004293 ! type I spiral ligament fibrocyte morphology

[Term]
id: MT:0004488
name: type II spiral ligament fibrocyte integrity
namespace: Trait.ontology
def: "susceptibility of type II spiral ligament fibrocytes to degeneration or loss" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004294 ! type II spiral ligament fibrocytes morphology

[Term]
id: MT:0004489
name: type III spiral ligament fibrocyte integrity
namespace: Trait.ontology
def: "susceptibility of type III spiral ligament fibrocytes to degeneration or loss" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004295 ! type III spiral ligament fibrocyte morphology

[Term]
id: MT:0004490
name: type IV spiral ligament fibrocyte integrity
namespace: Trait.ontology
def: "susceptibility of type IV spiral ligament fibrocytes to degeneration or loss" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0004296 ! type IV spiral ligament fibrocyte morphology

[Term]
id: MT:0004491
name: orientation of outer hair cell stereociliary bundles
namespace: Trait.ontology
def: "rotational direction of outer hair cell (OHC) stereociliary bundles, resulting in planar cell polarity of the inner ear sensory epithelium " [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000892 ! orientation of cochlear hair cell stereociliary bundles
is_a: MT:0001028 ! outer hair cell stereociliary bundle morphology

[Term]
id: MT:0004492
name: orientation of inner hair cell stereociliary bundles
namespace: Trait.ontology
def: "rotational direction of inner hair cell (IHC) stereociliary bundles, resulting in planar cell polarity of the inner ear sensory epithelium" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator]
is_a: MT:0000892 ! orientation of cochlear hair cell stereociliary bundles
is_a: MT:0001180 ! inner hair cell stereociliary bundle morphology

[Term]
id: MT:0004493
name: cochlear size
namespace: Trait.ontology
def: "area or volume of the cochlea" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0000031 ! cochlea morphology

[Term]
id: MT:0005000
name: immune tolerance
namespace: Trait.ontology
def: "the failure to respond to an antigen" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
is_a: MT:0001790 ! immune system physiology

[Term]
id: MT:0005001
name: clonal deletion
namespace: Trait.ontology
def: "a defect in the process of removal of immature lymphocytes that interact with self antigens during maturation" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "clonal deletion abnormalities" EXACT []
is_a: MT:0005000 ! immune tolerance

[Term]
id: MT:0005002
name: T cell clonal deletion
namespace: Trait.ontology
def: "a defect in the process of removal of immature T lymphocytes that interact with self antigens during maturation" [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "T cell clonal deletion abnormalities" EXACT []
synonym: "T lymphocyte clonal deletion abnormalities" EXACT []
synonym: "T-cell clonal deletion abnormalities" EXACT []
is_a: MT:0005001 ! clonal deletion

[Term]
id: MT:0005004
name: clonal anergy
namespace: Trait.ontology
def: "unresponsiveness to an antigen" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "anergy" EXACT []
is_a: MT:0005000 ! immune tolerance

[Term]
id: MT:0005005
name: self tolerance
namespace: Trait.ontology
def: "a defect in the normal lack of response to autologous (self) antigens" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "self tolerance abnormalities" EXACT []
is_a: MT:0005000 ! immune tolerance

[Term]
id: MT:0005006
name: osteoblast physiology
namespace: Trait.ontology
def: "anomalous function of this bone-forming cell, which normally forms an osseous matrix in which it becomes enclosed as an osteocyte" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001533 ! skeleton physiology

[Term]
id: MT:0005007
name: bone density
namespace: Trait.ontology
def: "abnormal mineral content of bone" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_chkn
synonym: "bone density anomalies" EXACT []
is_a: MT:0002896 ! bone mineralization

[Term]
id: MT:0005008
name: osteoblast formation
namespace: Trait.ontology
def: "anomalous development of this bone-forming cell, which normally forms an osseous matrix in which it becomes enclosed as an osteocyte" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal osteoplast formation" EXACT []
is_a: MT:0000057 ! osteogenesis

[Term]
id: MT:0005010
name: CD8+ T cell morphology/development
namespace: Trait.ontology
def: "anomalous structure, formation, or numbers of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "CD8+ T cell abnormalities" EXACT []
synonym: "CD8+ T-cell abnormalities" EXACT []
is_a: MT:0002435 ! effector T cell morphology/development

[Term]
id: MT:0005012
name: eosinophil count
namespace: Trait.ontology
def: "fewer than normal eosinophil numbers " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "decreased eosinophil number" EXACT []
is_a: MT:0000334 ! granulocyte number
is_a: MT:0002443 ! eosinophil morphology/development

[Term]
id: MT:0005018
name: T cell number
namespace: Trait.ontology
def: "fewer than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "decreased T cell count" EXACT []
synonym: "decreased T-cell count" EXACT []
synonym: "decreased T-cell number" EXACT []
is_a: MT:0002145 ! T lymphocyte development

[Term]
id: MT:0005019
name: early pro-B cell morphology/development
namespace: Trait.ontology
def: "anomalous structure, development, or number of cells in the B lymphocyte lineage that undergo D-J rearrangement of the immunoglobulin heavy chain" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
comment: these cells express no surface Ig; cell surface markers for these cells are: CD45R, MHC class II, CD19, CD38, CD40
synonym: "early pro-B cell abnormalities" EXACT []
synonym: "early pro-B-cell abnormalities" EXACT []
is_a: MT:0005432 ! pro-B cell morphology/development

[Term]
id: MT:0005020
name: late pro-B cell morphology/development
namespace: Trait.ontology
def: "anomalous structure, development, or number of the cells in the B lymphocyte lineage that undergo V-DJ rearrangement of the immunoglobulin heavy chain" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
comment: these cells express no surface Ig; cell surface markers for these cells are: CD45R, MHC class II, CD19, CD38, CD40
synonym: "late pro-B cell abnormalities" EXACT []
synonym: "late pro-B-cell abnormalities" EXACT []
is_a: MT:0005432 ! pro-B cell morphology/development

[Term]
id: MT:0005022
name: immature B cell morphology/development
namespace: Trait.ontology
def: "anomalous structure, development, or number of the cells of the B lymphocyte lineage that have undergone VDJ rearrangement of the heavy chain and V-J rearrangement of the light chain; these cells express IgM on the cell surface but have not yet been selected for self-reactivity" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
comment: these cells express IgM on their surface, in addition MT: CD45R, MHC class II, CD19, CD20, CD21, CD40
synonym: "immature B cell abnormalities" EXACT []
synonym: "immature B lymphocyte abnormalities" EXACT []
synonym: "immature B-cell abnormalities" EXACT []
is_a: MT:0002144 ! B lymphocyte development

[Term]
id: MT:0005023
name: wound healing
namespace: Trait.ontology
def: "aberrant process of repair of trauma to any tissues of the body, especially that caused by physical means" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005164 ! response to injury

[Term]
id: MT:0005024
name: lymph node structure
namespace: Trait.ontology
def: "anomaly in lymph node morphology" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002339 ! lymph node morphology

[Term]
id: MT:0005025
name: response to infection
namespace: Trait.ontology
def: "the body's reaction to invasion and multiplication of microorganisms in its tissues, or the body's reaction to components of or toxins produced by pathogenic microorganisms" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0001790 ! immune system physiology

[Term]
id: MT:0005026
name: susceptibility to parasitic infection
namespace: Trait.ontology
def: "reduced likelihood that an organism will develop ill effects from a parasitic infection or from components of or toxins produced by parasites" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_cattle
synonym: "increased resistance to parasitic infection" EXACT []
is_a: MT:0001793 ! susceptibility to infection

[Term]
id: MT:0005028
name: trophectoderm morphology
namespace: Trait.ontology
def: "malformed outermost layer of cells in the blastodermic vesicle, which will develop into the trophoblast layer and then contact the endometrium and take part in establishing the embryo's means of nutrition" [dlb:Donna Burkart_Mouse Genome Informatics Curator, J:57761, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001712 ! placental development
is_a: MT:0002085 ! embryonic tissue morphology

[Term]
id: MT:0005029
name: amnion morphology
namespace: Trait.ontology
def: "malformed innermost layer of the extraembryonic membranes" [dlb:Donna Burkart_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002086 ! extraembryonic tissue morphology

[Term]
id: MT:0005031
name: trophoblast layer morphology
namespace: Trait.ontology
def: "malformation of the mesectodermal cell layer arising from the trophectoderm that erodes the uterine mucosa and contributes to the formation of the placenta" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal trophoblast" RELATED []
is_a: MT:0001711 ! placenta morphology

[Term]
id: MT:0005032
name: ectoplacental cone morphology
namespace: Trait.ontology
def: "any morphological anomaly of the thickened trophoblast of the blastocyst in rodents that becomes the fetal portion of the placenta" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0001712 ! placental development

[Term]
id: MT:0005033
name: trophoblast giant cell morphology
namespace: Trait.ontology
def: "anomaly of the cells covering the blastocyst that erode the uterine mucosa and contribute to the formation of the placenta" [dlb:Donna Burkart_Mouse Genome Informatics Curator, J:57761, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005031 ! trophoblast layer morphology

[Term]
id: MT:0005034
name: anus morphology
namespace: Trait.ontology
def: "structural anomaly of the lower opening of the digestive tract" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal anus" EXACT []
synonym: "anus abnormalities" EXACT []
is_a: MT:0000462 ! digestive system morphology

[Term]
id: MT:0005035
name: perianal ulceration
namespace: Trait.ontology
def: "lesion around or near the anus" [cml:Cathleen M. Lutz_Mouse Genome Informatics Curator, J:71506]
is_a: MT:0005034 ! anus morphology

[Term]
id: MT:0005036
name: diarrhea
namespace: Trait.ontology
def: "abnormally frequent discharge of semi-solid or fluid fecal matter from the bowel" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003866 ! defecation

[Term]
id: MT:0005037
name: mucous diarrhea
namespace: Trait.ontology
def: "presence of considerable mucous in the stools" [J:71506, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "anal mucous discharge" EXACT []
is_a: MT:0005036 ! diarrhea

[Term]
id: MT:0005040
name: MHC II cell surface expression on macrophages
namespace: Trait.ontology
def: "anomaly in the ability of macrophages to express major histocompatibility complex class II at the cell surface" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:31326]
is_a: MT:0002454 ! macrophage antigen presentation
is_a: MT:0005042 ! level of surface class II molecules

[Term]
id: MT:0005041
name: antigen presentation via MHC class II
namespace: Trait.ontology
alt_id: MT:0001843
def: "anomaly in the process by which peptide, bound to major histocompatibility complex class II, is presented to lymphocytes at the surface of antigen presenting cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0001835 ! antigen presentation
is_a: MT:0002453 ! B lymphocyte antigen presentation

[Term]
id: MT:0005042
name: level of surface class II molecules
namespace: Trait.ontology
def: "deviation from the normal concentration of major histocompatibility complex class II molecules expressed at the cell surface" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
comment: unlike class I, which is expressed by almost all nucleated cells, only B cells, macrophages, other antigen presenting cells (e.g., Langerhans' cells), and epithelial cells of the thymus express MHC class II at their surface
is_a: MT:0005041 ! antigen presentation via MHC class II

[Term]
id: MT:0005043
name: assembly of class II molecules
namespace: Trait.ontology
def: "impaired production of major histocompatibility complex class II molecules" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0005041 ! antigen presentation via MHC class II

[Term]
id: MT:0005044
name: sepsis
namespace: Trait.ontology
def: "presence of various pathogenic organisms, or their toxins, in the blood or tissues" [J:82434, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005025 ! response to infection

[Term]
id: MT:0005045
name: thymus cortex area
namespace: Trait.ontology
def: "reduced size of outer section of the thymus lobule" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:31167]
is_a: MT:0002371 ! thymus cortex morphology

[Term]
id: MT:0005046
name: spleen white pulp formation
namespace: Trait.ontology
def: "lack of development of the lymphoid area of the spleen" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:31167]
synonym: "absent spleen white pulp" EXACT []
is_a: MT:0002357 ! spleen white pulp morphology

[Term]
id: MT:0005047
name: celiac lymph node size
namespace: Trait.ontology
def: "increased size of the celiac lymph nodes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:31167]
is_a: MT:0000701 ! lymph node size

[Term]
id: MT:0005048
name: thrombosis
namespace: Trait.ontology
def: "formation within a tissue or the vascular lumen of a thrombus, an aggregation of coagulated blood containing platelets, fibrin, and entrapped cellular elements " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology:ISBN 0-397-51047-0]
is_a: MT:0002551 ! blood coagulation

[Term]
id: MT:0005049
name: cytokine physiology
namespace: Trait.ontology
def: "functional anomaly of any of the non-antibody proteins made by inflammatory leukocytes and some non-leukocytic cells that affect the behavior of other cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
subset: slim_pig
is_a: MT:0002501 ! inflammatory mediator physiology

[Term]
id: MT:0005050
name: chemotactic interleukin physiology
namespace: Trait.ontology
def: "functional anomaly of any of a subset of interleukins that are involved in attracting leukocytes to a site of tissue injury" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "chemotactic interleukins" EXACT []
is_a: MT:0002526 ! chemokine physiology

[Term]
id: MT:0005051
name: response to anesthetics
namespace: Trait.ontology
def: "a reaction that differs from normal to compounds that reversibly depress neuronal function" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "altered sensitivity to anesthetics" EXACT []
is_a: MT:0002585 ! response/metabolism to xenobiotics

[Term]
id: MT:0005053
name: response to pentobarbital
namespace: Trait.ontology
def: "a reaction to this anesthetic that differs from normal " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "altered sensitivity to pentobarbital" EXACT []
is_a: MT:0005051 ! response to anesthetics

[Term]
id: MT:0005054
name: response to tribromoethanol
namespace: Trait.ontology
def: "a reaction to this anesthetic that differs from normal " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "altered sensitivity to tribromoethanol" EXACT []
is_a: MT:0005051 ! response to anesthetics

[Term]
id: MT:0005055
name: response to alphaxalone
namespace: Trait.ontology
def: "a reaction to this anesthetic that differs from normal " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "altered sensitivity to alphaxalone" EXACT []
is_a: MT:0005051 ! response to anesthetics

[Term]
id: MT:0005058
name: lysosome morphology
namespace: Trait.ontology
def: "anomalous structure of any of the cytoplasmic, membrane bound vesicles that contain a variety of hydrolases" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal lysosome" EXACT []
xref: GO:0005764
is_a: MT:0000358 ! cell content/ morphology

[Term]
id: MT:0005059
name: lysosomal protein accumulation
namespace: Trait.ontology
def: "buildup of protein in the lysosome" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
xref: GO:0007041
is_a: MT:0003172 ! lysosome physiology

[Term]
id: MT:0005060
name: accumulation of giant lysosomes in kidney/renal tubule cells
namespace: Trait.ontology
def: "buildup of contents in lysosomes in cells of the kidney tubules " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:5590]
is_a: MT:0002703 ! renal tubule morphology
is_a: MT:0005058 ! lysosome morphology

[Term]
id: MT:0005061
name: eosinophil morphology
namespace: Trait.ontology
def: "structural anomaly of the granular leukocytes having a two-lobed nucleus and cytoplasm containing coarse, round granules that are uniform in size and stainable by eosin" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "eosinophil structural abnormalities" EXACT []
is_a: MT:0002443 ! eosinophil morphology/development

[Term]
id: MT:0005062
name: presence of giant granules in eosinophils
namespace: Trait.ontology
def: "increased size of granules within these cells" [J:5078]
is_a: MT:0005061 ! eosinophil morphology

[Term]
id: MT:0005064
name: presence of giant granules in lymphocytes
namespace: Trait.ontology
def: "increased size of granules within these cells" [J:5078]
is_a: MT:0002619 ! lymphocyte morphology/development

[Term]
id: MT:0005065
name: neutrophil morphology
namespace: Trait.ontology
def: "structural anomaly of the granular leukocytes that have a three- to five-lobed nucleus and a cytoplasm that contains inconspicuous granules stainable by neutral dyes" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal polymorphonuclear cell" EXACT []
synonym: "neutrophil structural abnormalities" EXACT []
is_a: MT:0002415 ! neutrophil morphology/development

[Term]
id: MT:0005066
name: presence of giant granules in neutrophils
namespace: Trait.ontology
def: "increased size of the granules within these cells" [J:5078]
is_a: MT:0005065 ! neutrophil morphology

[Term]
id: MT:0005067
name: presence of melanin granules in retina
namespace: Trait.ontology
def: "pigment particles found in retina" [J:5078]
is_a: MT:0005103 ! retinal pigmentation

[Term]
id: MT:0005068
name: NK cell morphology/development
namespace: Trait.ontology
def: "anomalous structure, differentiation, or number of non-T, non-B lymphocytes, having a granular morphology and which are important in innate immunity to viruses and other intracellular pathogens; in addition, these cells can kill certain tumor cells" [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "abnormal NK cells" EXACT []
synonym: "natural killer cell abnormalities" EXACT []
synonym: "NK cell abnormalities" EXACT []
is_a: MT:0002619 ! lymphocyte morphology/development

[Term]
id: MT:0005069
name: NK cell physiology
namespace: Trait.ontology
def: "impaired function of non-T, non-B lymphocytes, having a granular morphology and which are important in innate immunity to viruses and other intracellular pathogens; in addition, these cells can kill certain tumor cells" [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "dysfunctional NK cells" EXACT []
synonym: "natural killer cell dysfunction" EXACT []
synonym: "NK cell dysfunction" EXACT []
is_a: MT:0003945 ! lymphocyte physiology

[Term]
id: MT:0005071
name: hair follicle melanin granule size
namespace: Trait.ontology
def: "increased size of the pigment particles in the hair follicle" [J:5078]
is_a: MT:0005072 ! hair follicle melanin granule morphology

[Term]
id: MT:0005072
name: hair follicle melanin granule morphology
namespace: Trait.ontology
def: "anomalous pigment particles in the hair follicles" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "hair follicle melanin granule abnormalities" EXACT []
is_a: MT:0002076 ! hair follicle structure/orientation
is_a: MT:0004381 ! hair follicle melanocyte morphology
is_a: MT:0005075 ! melanosome morphology

[Term]
id: MT:0005073
name: granulocyte chemotaxis
namespace: Trait.ontology
def: "inability or reduced ability of neutrophils, eosinophils, or basophils to move in response to chemical stimuli" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:5405, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002462 ! granulocyte physiology

[Term]
id: MT:0005074
name: granulocyte bactericidal activity
namespace: Trait.ontology
def: "inability or reduced ability of neutrophils, eosinophils, or basophils to kill bacteria" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:5405]
is_a: MT:0002462 ! granulocyte physiology

[Term]
id: MT:0005075
name: melanosome morphology
namespace: Trait.ontology
def: "anomalous structure of these tissue-specific cytoplasmic organelles within which melanin pigments are synthesized and stored" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:5346]
synonym: "abnormal melanosome" EXACT []
xref: GO:0042470
is_a: MT:0002877 ! melanocyte morphology

[Term]
id: MT:0005076
name: cell differentiation
namespace: Trait.ontology
def: "anomaly in the process whereby relatively unspecialized cells, e. g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
xref: GO:0030154
is_a: MT:0005621 ! cell physiology

[Term]
id: MT:0005077
name: melanogenesis
namespace: Trait.ontology
def: "failure of or anomaly in the biosynthetic pathway of melanin formation in cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:5346]
is_a: MT:0001186 ! pigmentation trait

[Term]
id: MT:0005078
name: cytotoxic T cell physiology
namespace: Trait.ontology
def: "impaired function of the subset of CD8+ T lymphocytes capable of directly killing appropriately targeted cells " [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "CTL dysfunction" EXACT []
synonym: "cytotoxic T cell dysfunction" EXACT []
synonym: "cytotoxic T lymphocyte dysfunction" EXACT []
synonym: "cytotoxic T-cell dysfunction" EXACT []
is_a: MT:0004392 ! CD8+ T cell physiology

[Term]
id: MT:0005079
name: cytotoxic T cell cytolysis
namespace: Trait.ontology
def: "impaired ability of these cells to destroy or dissolve targeted cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:6692]
synonym: "defective CTL cytolysis" EXACT []
synonym: "defective cytotoxic T lymphocyte cytolysis" EXACT []
synonym: "defective cytotoxic T-cell cytolysis" EXACT []
is_a: MT:0005078 ! cytotoxic T cell physiology

[Term]
id: MT:0005081
name: stratum reticulare morphology
namespace: Trait.ontology
def: "structural anomaly of the thicker, deeper layer of the dermis, containing blood and lymph vessels, nerves and nerve endings, and hair follicles" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal stratum reticulare" EXACT []
synonym: "abnormal stratum reticulare corii" EXACT []
synonym: "abnormal stratum reticulare cutis" EXACT []
synonym: "abnormal tunica propria corii" EXACT []
is_a: MT:0001243 ! dermal layer morphology

[Term]
id: MT:0005082
name: clear layer morphology
namespace: Trait.ontology
def: "structural or developmental anomaly of the layer of lightly staining corneocytes in the deepest level of the stratum corneum; found primarily in the thick epidermis of the palmar and plantar skin" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal stratum lucidum" EXACT []
is_a: MT:0001240 ! cornified layer morphology

[Term]
id: MT:0005083
name: biliary tract morphology
namespace: Trait.ontology
def: "anomalous structure or development of the gall bladder or its ducts" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal biliary tract" EXACT []
is_a: MT:0002138 ! liver/biliary system morphology

[Term]
id: MT:0005084
name: gall bladder morphology
namespace: Trait.ontology
def: "anomalous structure or development of the organ which serves as a storage reservoir for bile" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal gall bladder" EXACT []
synonym: "gallbladder abnormalities" EXACT []
is_a: MT:0005083 ! biliary tract morphology

[Term]
id: MT:0005085
name: gall bladder physiology
namespace: Trait.ontology
def: "anomalous action or function of the organ that stores and concentrates bile" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal gall bladder function" EXACT []
synonym: "abnormal gallbladder function" EXACT []
is_a: MT:0002139 ! liver/biliary system physiology

[Term]
id: MT:0005086
name: bile volume
namespace: Trait.ontology
def: "anomalous amount of bile in the gall bladder" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:82951]
is_a: MT:0005085 ! gall bladder physiology

[Term]
id: MT:0005089
name: double-negative T cell count
namespace: Trait.ontology
def: "reduced numbers of the subset of T cells found in the thymus that express neither CD4 nor CD8" [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "decreased CD4-CD8- T cell count" EXACT []
synonym: "decreased CD4-CD8- T cell numbers" EXACT []
synonym: "decreased double-negative T cell numbers" EXACT []
synonym: "decreased double-negative T-cell numbers" EXACT []
is_a: MT:0002407 ! double-negative T cell morphology/development

[Term]
id: MT:0005092
name: double-positive T cell count
namespace: Trait.ontology
def: "less than the expected number of the subset of T cells found in the thymus that express both CD4 and CD8" [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "decreased CD4+CD8+ T cell count" EXACT []
synonym: "decreased CD4+CD8+ T cell numbers" EXACT []
synonym: "decreased double-positive T cell numbers" EXACT []
synonym: "decreased double-positive T-cell numbers" EXACT []
is_a: MT:0002408 ! double-positive T cell morphology/development

[Term]
id: MT:0005094
name: T cell proliferation
namespace: Trait.ontology
def: "anomaly in the clonal expansion of naive T cells" [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "abnormal T-cell proliferation" EXACT []
is_a: MT:0001828 ! T cell activation

[Term]
id: MT:0005096
name: erythroblastosis
namespace: Trait.ontology
def: "presence of erythroblasts in great number in the blood" [J:305, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001586 ! erythrocyte count

[Term]
id: MT:0005097
name: polychromatophilia
namespace: Trait.ontology
def: "condition characterized by the presence of red blood cells that have an affinity for acid, basic, and neutral stains" [J:305, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "polychromasia" EXACT []
is_a: MT:0002447 ! erythrocyte morphology

[Term]
id: MT:0005098
name: choroid morphology
namespace: Trait.ontology
def: "anomalous structure of the thin, highly vascularized membrane covering most of the posterior of the eye between the retina and the sclera" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "choroid abnormalities" EXACT []
is_a: MT:0005196 ! posterior uvea morphology

[Term]
id: MT:0005099
name: ciliary body morphology
namespace: Trait.ontology
def: "structural anomaly of the thickened portion of the vascular tunic, which lies between the choroid and the iris" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "ciliary body abnormalities" EXACT []
is_a: MT:0005194 ! anterior uvea morphology

[Term]
id: MT:0005100
name: choroid pigmentation
namespace: Trait.ontology
def: "anomalous coloring of the thin, highly vascularized membrane covering most of the posterior of the eye between the retina and the sclera" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001324 ! eye pigmentation
is_a: MT:0005098 ! choroid morphology

[Term]
id: MT:0005101
name: ciliary body pigmentation
namespace: Trait.ontology
def: "anomalous coloring of the thickened portion of the vascular tunic, which lies between the choroid and the iris" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005200 ! pigment epithelium of the eye

[Term]
id: MT:0005102
name: iris pigmentation
namespace: Trait.ontology
def: "anomalous coloring of the adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001322 ! iris morphology
is_a: MT:0001324 ! eye pigmentation

[Term]
id: MT:0005103
name: retinal pigmentation
namespace: Trait.ontology
def: "anomalous coloring of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005201 ! retinal pigment epithelium morphology

[Term]
id: MT:0005104
name: tarsus morphology
namespace: Trait.ontology
def: "malformation or absence of any of the eight bones of the instep of the paw: tibiale, talus, calcaneus, navicular, 3 cuneiform, and cuboid bones" [Anatomy of the Rat:Greene EC_Hafner Publishing Co_1935, J:83132, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
comment: Note that humans only have seven tarsal bones, while rodents have eight.
synonym: "abnormal tarsal bone" EXACT []
synonym: "abnormal tarsals" EXACT []
synonym: "abnormal tarsus" EXACT []
is_a: MT:0002115 ! skeleton extremities morphology

[Term]
id: MT:0005105
name: middle ear ossicle morphology
namespace: Trait.ontology
alt_id: MT:0003738
def: "form or structure of the three small bones of the middle ear" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "middle ear bone morphology" EXACT []
is_a: MT:0000049 ! middle ear morphology
is_a: MT:0005508 ! skeleton morphology

[Term]
id: MT:0005106
name: incus morphology
namespace: Trait.ontology
def: "form or structure of the middle of the three auditory ossicles" [J:83132, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005105 ! middle ear ossicle morphology

[Term]
id: MT:0005107
name: stapes morphology
namespace: Trait.ontology
def: "structure or form of the smallest and innermost of the three auditory ossicles" [J:83132, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal stapes" EXACT []
is_a: MT:0005105 ! middle ear ossicle morphology

[Term]
id: MT:0005108
name: ulna morphology
namespace: Trait.ontology
def: "malformation of the medial and larger of the two bones of the forearm" [J:83132, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal ulna" EXACT []
is_a: MT:0003723 ! long bone morphology

[Term]
id: MT:0005109
name: talus morphology
namespace: Trait.ontology
def: "malformation of the bone that articulates with the tibia and fibula" [J:83132, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal ankle bone" EXACT []
synonym: "abnormal talus" EXACT []
is_a: MT:0005104 ! tarsus morphology

[Term]
id: MT:0005110
name: talus size
namespace: Trait.ontology
def: "length, width, or area of the bone that articulates with the tibia and fibula" [J:83132, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005109 ! talus morphology

[Term]
id: MT:0005112
name: anterior horn morphology
namespace: Trait.ontology
def: "anomalous structure of the ventral gray column of the spinal cord" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal anterior horn" EXACT []
synonym: "abnormal ventral horn" EXACT []
is_a: MT:0000955 ! spinal cord morphology

[Term]
id: MT:0005113
name: number of anterior horn cells
namespace: Trait.ontology
def: "fewer than the expected number of cells in the ventral gray column of the spinal cord" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005112 ! anterior horn morphology

[Term]
id: MT:0005116
name: circulating pituitary hormone level
namespace: Trait.ontology
alt_id: MT:0005115
def: "aberration in the blood concentration of any of the hormones secreted by the pituitary" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "abnormal circulating level of pituitary hormone" EXACT []
synonym: "abnormal serum level of pituitary hormone" EXACT []
is_a: MT:0003965 ! pituitary hormone level
is_a: MT:0005418 ! circulating hormone level

[Term]
id: MT:0005119
name: circulating thyroid-stimulating hormone level
namespace: Trait.ontology
def: "less than expected blood concentration of the hormone that stimulates the growth and function of the thyroid gland" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_pig
synonym: "decreased serum levels of thyroid-stimulating hormone" EXACT []
synonym: "decreased serum levels of thyropic hormone" EXACT []
synonym: "decreased serum levels of thyrotrophin" EXACT []
synonym: "decreased serum levels of thyrotropin" EXACT []
synonym: "decreased serum levels of TSH" EXACT []
is_a: MT:0003971 ! thyroid-stimulating hormone level
is_a: MT:0005116 ! circulating pituitary hormone level

[Term]
id: MT:0005120
name: circulating growth hormone level
namespace: Trait.ontology
def: "less than the expected blood concentration of the hormone that promotes body growth, fat mobilization, and inhibition of glucose utilization" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "decreased serum levels of GH" EXACT []
synonym: "decreased serum levels of growth hormone" EXACT []
synonym: "decreased serum levels of pituitary growth hormone" EXACT []
synonym: "decreased serum levels of somatotropic hormone" EXACT []
synonym: "decreased serum levels of somatropin" EXACT []
is_a: MT:0003968 ! growth hormone level
is_a: MT:0005116 ! circulating pituitary hormone level

[Term]
id: MT:0005121
name: circulating prolactin level
namespace: Trait.ontology
def: "less than expected blood concentration of the hormone that stimulates milk secretion " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "decreased serum levels of galactopoietic hormone" EXACT []
synonym: "decreased serum levels of lactation hormone" EXACT []
synonym: "decreased serum levels of lactogenic hormone" EXACT []
synonym: "decreased serum levels of lactotropin" EXACT []
synonym: "decreased serum levels of mammotropic factor" EXACT []
synonym: "decreased serum levels of mammotropic hormone" EXACT []
synonym: "decreased serum levels of PRL" EXACT []
synonym: "decreased serum levels of prolactin" EXACT []
is_a: MT:0003361 ! circulating gonadotropin level
is_a: MT:0003970 ! prolactin level
is_a: MT:0005116 ! circulating pituitary hormone level

[Term]
id: MT:0005144
name: circulating VLDL cholesterol level
namespace: Trait.ontology
def: "anomalous concentration in the blood of very low density lipoprotein, which normally transports triglycerides from the intestine and liver to muscle and adipose tissue" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal VLDL cholesterol level" EXACT []
is_a: MT:0000180 ! circulating cholesterol level

[Term]
id: MT:0005149
name: gubernaculum morphology
namespace: Trait.ontology
def: "dysmorphology of the genitoinguinal ligaments that, in the male, connect the fetal testis to the developing scrotum, and, in the female, connect the ovaries to the uterus" [J:55881, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal gubernaculae" EXACT []
is_a: MT:0002160 ! reproductive system morphology

[Term]
id: MT:0005150
name: cachexia
namespace: Trait.ontology
def: "general weight loss and wasting occurring in the course of chronic disease" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "emaciation" EXACT []
synonym: "wasting" EXACT []
is_a: MT:0001263 ! weight loss

[Term]
id: MT:0005151
name: diffuse hepatic necrosis
namespace: Trait.ontology
def: "disseminated pathologic death of cells within the liver" [J:20450, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001654 ! hepatic necrosis

[Term]
id: MT:0005152
name: pancytopenia
namespace: Trait.ontology
def: "reduction in the number of erythrocytes, all types of white blood cells, and platelets in the circulating blood" [J:20450, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000221 ! WBC count
is_a: MT:0000228 ! thrombopoiesis
is_a: MT:0001586 ! erythrocyte count

[Term]
id: MT:0005153
name: B cell proliferation
namespace: Trait.ontology
def: "change from normal in the ability of B cells to grow and divide in response to stimuli " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal B lymphocyte proliferation" EXACT []
synonym: "abnormal B-cell proliferation" EXACT []
is_a: MT:0002459 ! B cell physiology

[Term]
id: MT:0005155
name: herniated intestine
namespace: Trait.ontology
def: "protrusion of any portion of the intestine from its normal anatomical position" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "intestinal hernia" EXACT []
synonym: "intestinal herniation" EXACT []
is_a: MT:0000477 ! intestine morphology

[Term]
id: MT:0005157
name: holoprosencephaly
namespace: Trait.ontology
def: "presence of a single forebrain hemisphere or lobe; often accompanied by a deficit in median facial development" [J:83058, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000913 ! brain development

[Term]
id: MT:0005158
name: ovary cell number
namespace: Trait.ontology
def: "underdeveloped ovaries, usually due to reduced cell number" [J:78931, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "hypoplastic ovaries" EXACT []
synonym: "hypoplastic ovary" EXACT []
synonym: "ovarian hypoplasia" EXACT []
is_a: MT:0001127 ! ovary size

[Term]
id: MT:0005159
name: azoospermia
namespace: Trait.ontology
def: "absence of living spermatozoa " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "absence of sperm" EXACT []
synonym: "absent sperm" EXACT []
synonym: "aspermia" EXACT []
is_a: MT:0001156 ! spermatogenesis
is_a: MT:0002209 ! germ cell number
is_a: MT:0002673 ! sperm count

[Term]
id: MT:0005160
name: urine protein level
namespace: Trait.ontology
def: "presence of excess serum protein in the urine, usually albumin, but also globulin" [J:78193, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001757 ! urine chemistry

[Term]
id: MT:0005161
name: hematuria
namespace: Trait.ontology
def: "presence of blood in the urine" [J:78193, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001757 ! urine chemistry

[Term]
id: MT:0005162
name: ability to move the wrist/hand
namespace: Trait.ontology
is_a: MT:0000753 ! ability to move

[Term]
id: MT:0005163
name: cyclopia
namespace: Trait.ontology
def: "a congenital defect in which the two orbits are united to form a single cavity containing one eye" [J:60303, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "cyclopea" EXACT []
synonym: "one eye" EXACT []
synonym: "synophthalmia" EXACT []
synonym: "synophthalmus" EXACT []
is_a: MT:0001286 ! eye development

[Term]
id: MT:0005164
name: response to injury
namespace: Trait.ontology
def: "anomaly in the body's reaction to trauma, especially that by physical means" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001790 ! immune system physiology

[Term]
id: MT:0005166
name: susceptibility to injury
namespace: Trait.ontology
def: "less than the normal reaction to trauma, especially that by physical means" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "decreased response to injury" EXACT []
is_a: MT:0005164 ! response to injury

[Term]
id: MT:0005167
name: blood-brain barrier integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the group of barriers and transport systems in the brain capillary endothelium that controls the entrance of substances into the brain extracellular space from the blood" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
comment: this should only be in the morphology branch
relationship: part_of MT:0000075 ! blood-brain barrier morphology

[Term]
id: MT:0005168
name: female meiosis
namespace: Trait.ontology
def: "malfunction in the process of nuclear division that results in ova with one half the normal chromosome number of the original cell" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
xref: GO:0007143
is_a: MT:0001930 ! meiosis
is_a: MT:0001931 ! oogenesis

[Term]
id: MT:0005169
name: male meiosis
namespace: Trait.ontology
def: "malfunction in the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
xref: GO:0007140
is_a: MT:0001156 ! spermatogenesis
is_a: MT:0001930 ! meiosis

[Term]
id: MT:0005170
name: cleft lip
namespace: Trait.ontology
def: "defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "harelip" EXACT []
is_a: MT:0003769 ! lip morphology

[Term]
id: MT:0005171
name: lack of coat pigmentation
namespace: Trait.ontology
def: "fur is devoid of coloration and appears white " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:83500]
synonym: "absent coat pigmentation" EXACT []
is_a: MT:0002075 ! coat color

[Term]
id: MT:0005172
name: lack of eye pigmentation
namespace: Trait.ontology
def: "visual organs are devoid of coloring pigment in relation to control animals, usually resulting in a red or pink color" [J:83500]
synonym: "ocular albinism" EXACT []
is_a: MT:0001324 ! eye pigmentation

[Term]
id: MT:0005174
name: tail pigmentation
namespace: Trait.ontology
def: "anomalous color of the tail in relation to control animals" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "tail pigmentation abnormalities" EXACT []
is_a: MT:0002095 ! skin pigmentation
is_a: MT:0002111 ! tail morphology

[Term]
id: MT:0005175
name: non-pigmented tail tip
namespace: Trait.ontology
def: "lack of color at the end of the tail " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:83500]
is_a: MT:0005174 ! tail pigmentation

[Term]
id: MT:0005176
name: eyelids fail to open
namespace: Trait.ontology
def: "eyes remain shut throughout life" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:83500]
synonym: "closed eyes" EXACT []
synonym: "eyelids don't open" EXACT []
synonym: "eyes fail to open" EXACT []
is_a: MT:0003671 ! eyelid opening

[Term]
id: MT:0005177
name: total circulating cholesterol level
namespace: Trait.ontology
alt_id: MT:0001549
def: "anomalous concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
synonym: "abnormal total plasma cholesterol level" EXACT []
synonym: "abnormal total serum cholesterol level" EXACT []
is_a: MT:0000180 ! circulating cholesterol level

[Term]
id: MT:0005180
name: circulating testosterone level
namespace: Trait.ontology
def: "aberration in the blood concentration of this most potent androgen" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal circulating level of testosterone" EXACT []
is_a: MT:0005418 ! circulating hormone level

[Term]
id: MT:0005183
name: circulating estradiol level
namespace: Trait.ontology
def: "aberration in the blood concentration of this most potent estrogen" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal circulating level of estradiol" EXACT []
is_a: MT:0003369 ! circulating estrogen level

[Term]
id: MT:0005184
name: circulating progesterone level
namespace: Trait.ontology
def: "aberration in the blood concentration of this antiestrogenic steroid" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_chkn
synonym: "abnormal circulating level of progesterone" EXACT []
is_a: MT:0005418 ! circulating hormone level

[Term]
id: MT:0005187
name: penis morphology
namespace: Trait.ontology
def: "anomalous structure of the organ of copulation and urination in the male" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000516 ! urinary system morphology
is_a: MT:0001145 ! male reproductive anatomy

[Term]
id: MT:0005189
name: anogenital distance
namespace: Trait.ontology
def: "the measure of the length of space from the genitals to the anus" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal ano-genital distance" EXACT []
is_a: MT:0003315 ! perineum morphology

[Term]
id: MT:0005190
name: osteomyelitis
namespace: Trait.ontology
def: "bone inflammation" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001533 ! skeleton physiology
is_a: MT:0001846 ! tissue specific inflammatory response

[Term]
id: MT:0005193
name: anterior eye segment morphology
namespace: Trait.ontology
alt_id: MT:0000095
def: "anomalous structure of any of the parts of the eye that lie in front of, or ventral to, the lens (inclusive)" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal anterior segment" EXACT []
is_a: MT:0002092 ! eye morphology

[Term]
id: MT:0005194
name: anterior uvea morphology
namespace: Trait.ontology
def: "anomalous structure of any of the parts of the front, or ventral, portion of the vascular, pigmentary, or middle coat of the eye, including the ciliary body and the iris" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "anterior uvea abnormalities" EXACT []
synonym: "Haller tunica vascula abnormalities" EXACT []
synonym: "tunica vasculosa bulbosa abnormalities" EXACT []
synonym: "uveal tract abnormalities" EXACT []
synonym: "vascular layer of the eyeball" EXACT []
synonym: "vascular tunic of the eye" EXACT []
synonym: "vasculosa oculi abnormalities" EXACT []
is_a: MT:0005193 ! anterior eye segment morphology
is_a: MT:0005197 ! uvea morphology

[Term]
id: MT:0005195
name: posterior eye segment morphology
namespace: Trait.ontology
def: "anomalous structure of any of the parts of the eye that lie in back of, or dorsal to, the lens (but not inclusive)" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "posterior eye segment abnormalities" EXACT []
is_a: MT:0002092 ! eye morphology

[Term]
id: MT:0005196
name: posterior uvea morphology
namespace: Trait.ontology
def: "structural anomaly of the rear, or dorsal, portion of the vascular, pigmentary, or middle coat of the eye, includes the choroid" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "posterior uvea abnormalities" EXACT []
synonym: "tunica vasculosa bulbi" EXACT []
synonym: "tunica vasculosa oculi abnormalities" EXACT []
synonym: "uveal tract abnormalities" EXACT []
synonym: "vascular layer of the eyeball" EXACT []
synonym: "vascular tunic of the eye abnormalities" EXACT []
is_a: MT:0002864 ! ocular fundus morphology
is_a: MT:0005197 ! uvea morphology

[Term]
id: MT:0005197
name: uvea morphology
namespace: Trait.ontology
def: "structural anomaly of the pigmented vascular coat of the eyeball, consisting of the iris, ciliary body, and choroid" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "uvea abnormalities" EXACT []
synonym: "vascular layer of the eyeball" EXACT []
is_a: MT:0002092 ! eye morphology

[Term]
id: MT:0005198
name: aqueous drainage system morphology
namespace: Trait.ontology
def: "anomalies in the structures associated with drainage of the aqueous humor from the eye, these include the trabecular meshwork, Schlemm's canal, the uveoscleral network, and the aqueous veins" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0005194 ! anterior uvea morphology

[Term]
id: MT:0005199
name: iris pigment epithelium
namespace: Trait.ontology
def: "anomaly in the epithelial layer of the iris composed of cells containing pigment granules" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001322 ! iris morphology
is_a: MT:0005200 ! pigment epithelium of the eye

[Term]
id: MT:0005200
name: pigment epithelium of the eye
namespace: Trait.ontology
def: "anomaly in the epithelial layer of the retina, ciliary body, or iris composed of cells containing pigment granules" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0001324 ! eye pigmentation

[Term]
id: MT:0005201
name: retinal pigment epithelium morphology
namespace: Trait.ontology
def: "anomaly in the epithelial layer of the retina composed of cells containing pigment granules" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0003727 ! retinal layer morphology
is_a: MT:0005200 ! pigment epithelium of the eye

[Term]
id: MT:0005202
name: level of alertness
namespace: Trait.ontology
is_a: MT:0003313 ! locomotor activation

[Term]
id: MT:0005203
name: trabecular meshwork morphology
namespace: Trait.ontology
def: "structural anomaly in the pore-like structure surrounding the entire circumference of the anterior chamber through which aqueous humor circulates" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0004221 ! iridocorneal angle morphology

[Term]
id: MT:0005204
name: canal of Schlemm morphology
namespace: Trait.ontology
def: "structural anomaly in the vascular structure encircling the anterior chamber of the eye, through which the aqueous humor is returned to the blood circulation" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "circular sinus abnormalities" EXACT []
synonym: "Fontana canal abnormalities" EXACT []
synonym: "Lauth canal abnormalities" EXACT []
synonym: "Schlemm's canal" EXACT []
synonym: "scleral venous sinus abnormalities" EXACT []
synonym: "sinus circularis abnormalities" EXACT []
synonym: "sinus venosus sclerae abnormalities" EXACT []
synonym: "venous sinus of sclera abnormalities" EXACT []
is_a: MT:0004221 ! iridocorneal angle morphology

[Term]
id: MT:0005205
name: eye anterior chamber
namespace: Trait.ontology
def: "anomaly of the space in the eye, filled with aqueous humor, and bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and part of the crystalline lens" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "eye anterior chamber abnormalities" EXACT []
is_a: MT:0005193 ! anterior eye segment morphology

[Term]
id: MT:0005206
name: aqueous humor morphology
namespace: Trait.ontology
def: "anomaly in the clear, watery fluid that fills the anterior and posterior chambers of the eye" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "aqueous humor abnormalities" EXACT []
is_a: MT:0005205 ! eye anterior chamber

[Term]
id: MT:0005207
name: aqueous vein morphology
namespace: Trait.ontology
def: "structural anomaly of this vessel that receives aqueous humor from the sinus venosus sclerae (canal of Schlemm)" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0004221 ! iridocorneal angle morphology

[Term]
id: MT:0005208
name: iris stroma morphology
namespace: Trait.ontology
def: "structural anomaly of the lamellated connective tissue of the iris" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0001322 ! iris morphology

[Term]
id: MT:0005209
name: gastric mucosa morphology
namespace: Trait.ontology
def: "anomaly of the surface epithelium of the stomach, which is made up of several different cell types " [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal gastric mucosa" EXACT []
is_a: MT:0000473 ! stomach glandular epithelium morphology

[Term]
id: MT:0005211
name: thickness of gastric mucosa
namespace: Trait.ontology
def: "depth or width of the epithelial layer of the stomach" [J:77398, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "expanded mucosal thickness of the stomach" EXACT []
is_a: MT:0005209 ! gastric mucosa morphology

[Term]
id: MT:0005212
name: immature goblet-like cells in stomach
namespace: Trait.ontology
def: "unusual appearance of stomach mucosa in which one finds cells resembling those that produce and secrete mucins" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:77398]
is_a: MT:0005209 ! gastric mucosa morphology

[Term]
id: MT:0005213
name: gastric metaplasia
namespace: Trait.ontology
def: "condition in which there is a change of one adult cell type to another adult cell type in the stomach " [J:77398, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0005209 ! gastric mucosa morphology

[Term]
id: MT:0005214
name: regional gastric metaplasia
namespace: Trait.ontology
def: "localized areas of the stomach in which there is a change from one adult cell type to another adult cell type" [J:77398, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0005213 ! gastric metaplasia

[Term]
id: MT:0005215
name: islet of Langerhans morphology
namespace: Trait.ontology
alt_id: MT:0001946
alt_id: MT:0005219
def: "anomalous morphology of these structures that are scattered throughout the pancreas and comprise its endocrine portion; within each islet there are three cell types: alpha, beta, and delta" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal endocrine pancreas" EXACT []
synonym: "abnormal islet of Langerhans" EXACT []
synonym: "beta cell abnormalities" EXACT []
synonym: "islet cell abnormalities" EXACT []
is_a: MT:0001944 ! pancreas morphology

[Term]
id: MT:0005216
name: pancreatic alpha cell morphology
namespace: Trait.ontology
def: "malformation of the cells of the pancreas that secrete glucagon" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal pancreatic alpha cells" EXACT []
is_a: MT:0005215 ! islet of Langerhans morphology

[Term]
id: MT:0005217
name: pancreatic beta cell morphology
namespace: Trait.ontology
def: "malformation of the cells of the pancreas that secrete insulin" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal pancreatic beta cells" EXACT []
is_a: MT:0005215 ! islet of Langerhans morphology

[Term]
id: MT:0005218
name: pancreatic delta cell morphology
namespace: Trait.ontology
def: "malformation of the cells found in the pancreas and gastrointestinal tract that secrete somatostatin" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal D cells" EXACT []
synonym: "abnormal pancreatic delta cells" EXACT []
is_a: MT:0005215 ! islet of Langerhans morphology

[Term]
id: MT:0005220
name: exocrine pancreas morphology
namespace: Trait.ontology
def: "malformation of the acinar gland portion of the pancreas that secretes digestive enzymes " [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal exocrine pancreas" EXACT []
is_a: MT:0001944 ! pancreas morphology

[Term]
id: MT:0005221
name: rostral-caudal axis patterning
namespace: Trait.ontology
alt_id: MT:0001703
def: "anomaly in the development or formation of the axis that runs from the head to the tail of the body" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal anterior-posterior axis patterning" EXACT []
synonym: "abnormal head-tail axis patterning" EXACT []
synonym: "abnormal rostro-caudal axis patterning" EXACT []
is_a: MT:0002084 ! developmental patterning

[Term]
id: MT:0005222
name: somite size
namespace: Trait.ontology
def: "atypical size of any of the segmental masses along the notochord of the developing embryo" [J:72325]
synonym: "irregular somite size" EXACT []
is_a: MT:0001688 ! somite development

[Term]
id: MT:0005223
name: anterior-posterior polarity of the somites
namespace: Trait.ontology
def: "anomalous development or formation of the somites along the axis that runs from the front to the back surface of the body" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:72325]
is_a: MT:0001688 ! somite development
is_a: MT:0005221 ! rostral-caudal axis patterning

[Term]
id: MT:0005224
name: left-right axis symmetry of the somites
namespace: Trait.ontology
def: "anomaly in the formation or development of the somites in relation to the left and right sides of the body " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "left-right asymmetry" EXACT []
is_a: MT:0001688 ! somite development
is_a: MT:0001706 ! left-right axis patterning

[Term]
id: MT:0005225
name: vertebrae development
namespace: Trait.ontology
def: "anomalous formation of the vertebrae from the sclerotome" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0000137 ! vertebrae morphology
is_a: MT:0002113 ! skeleton development

[Term]
id: MT:0005226
name: vertebral arch development
namespace: Trait.ontology
def: "anomalous formation of the posterior projection from the body of a vertebra that encloses the vertebral foramen " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005225 ! vertebrae development

[Term]
id: MT:0005227
name: vertebral body development
namespace: Trait.ontology
def: "anomalous formation of the main portion of the vertebra anterior to the vertebral canal, and distinct from the vertebral arch" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005225 ! vertebrae development

[Term]
id: MT:0005228
name: fusion of vertebral bodies/neural arches
namespace: Trait.ontology
def: "improper joining of the main portion of the vertebra anterior to the vertebral canal and the cartilaginous or bony arch that encloses and protects the spinal cord on the back" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "vertebral body/neural arch fusion" EXACT []
is_a: MT:0005227 ! vertebral body development

[Term]
id: MT:0005229
name: intervertebral disk development
namespace: Trait.ontology
def: "anomalous formation of the cartilaginous and gelatinous structure found between vertebrae" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal intervertebral disc formation" EXACT []
synonym: "abnormal intervertebral disk formation" EXACT []
is_a: MT:0000164 ! cartilage development
is_a: MT:0005225 ! vertebrae development

[Term]
id: MT:0005230
name: ectrodactyly
namespace: Trait.ontology
def: "absence of the middle rays, i.e., the central digits of the paws; usually associated with cleft paws and may also include syndactyly or aplasia of remaining digits" [OMIM:Online Mendelian Inheritance in Man]
is_a: MT:0002110 ! digit morphology

[Term]
id: MT:0005231
name: brachial lymph node morphology
namespace: Trait.ontology
def: "anomalous structure, development, or number of the lymph nodes located along the brachial vein that receive drainage from most of the free upper limb and send efferent vessels to the central axillary lymph nodes" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "brachial lymph node abnormalities" EXACT []
synonym: "humeral axillary lymph node abnormalities" EXACT []
is_a: MT:0002340 ! axillary lymph node morphology

[Term]
id: MT:0005232
name: mesenteric lymph node morphology
namespace: Trait.ontology
def: "anomalous structure, development, or number of the lymph nodes located in the mesentary, of which there are 3 classes: ileocolic, juxtaintestinal mesenteric, and central superior group" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "mesenteric lymph node abnormalities" EXACT []
is_a: MT:0002339 ! lymph node morphology

[Term]
id: MT:0005233
name: plasmacytoma
namespace: Trait.ontology
def: "discrete, presumably solitary mass of neoplastic plasma cells in bone or in one of the extramedullary sites" [J:78204, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0005234
name: thymic lymphoma
namespace: Trait.ontology
alt_id: MT:0003832
def: "a neoplasm originating from thymic tissue, usually benign, and frequently encapsulated" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "thymoma" EXACT []
is_a: MT:0002019 ! tumor incidence
is_a: MT:0002022 ! lymphoma

[Term]
id: MT:0005235
name: olfactory pathway morphology
namespace: Trait.ontology
def: "anomalous structure of any of the set of nerve fibers conducting impulses from olfactory receptors to the cerebral cortex, including the olfactory nerve; olfactory bulb; olfactory tract, olfactory tubercle, anterior perforated substance, and olfactory cortex" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal olfactory pathways" EXACT []
is_a: MT:0000787 ! telencephalon morphology

[Term]
id: MT:0005236
name: olfactory nerve morphology
namespace: Trait.ontology
alt_id: MT:0001057
def: "anomalous structure of the first cranial nerve, which conveys the sense of smell" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal olfactory nerve" EXACT []
synonym: "CN-I" EXACT []
synonym: "olfactory nerve abnormalities" EXACT []
is_a: MT:0001056 ! cranial nerve morphology
is_a: MT:0005235 ! olfactory pathway morphology

[Term]
id: MT:0005237
name: olfactory tract morphology
namespace: Trait.ontology
def: "structural anomaly of the nerve-like, white band composed primarily of nerve fibers originating from the mitral cells and tufted cells of the olfactory bulb, but also containing the scattered cells of the anterior olfactory nucleus" [J:34460, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal olfactory tract" EXACT []
is_a: MT:0005235 ! olfactory pathway morphology

[Term]
id: MT:0005239
name: Bruch membrane morphology
namespace: Trait.ontology
def: "anomalous structure of the transparent, nearly structureless inner layer of the choroid in contact with the pigmented layer of the retina" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "basal lamina of the choroid abnormalities" EXACT []
synonym: "basal layer of the choroid abnormalities" EXACT []
synonym: "Bruch's membrane abnormalities" EXACT []
synonym: "Henle membrane abnormalities" EXACT []
synonym: "lamina basalis choroidae abnormalities" EXACT []
synonym: "lamina vitrea abnormalities" EXACT []
synonym: "vitreous lamella abnormalities" EXACT []
is_a: MT:0005098 ! choroid morphology

[Term]
id: MT:0005240
name: amacrine cell morphology
namespace: Trait.ontology
def: "anomalous structure of the interneurons of the retina" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal amacrine cells" EXACT []
is_a: MT:0000965 ! sensory neuron morphology
is_a: MT:0001325 ! retina morphology

[Term]
id: MT:0005241
name: retinal ganglion layer morphology
namespace: Trait.ontology
def: "anomalous structure of the innermost nuclear layer of the retina, which projects axons through the optic nerve to the brain" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal retinal ganglion cell morphology" EXACT []
synonym: "abnormal retinal ganglion cells" EXACT []
is_a: MT:0006069 ! retinal neuronal layer morphology

[Term]
id: MT:0005245
name: hemarthrosis
namespace: Trait.ontology
def: "bleeding into a joint space" [Pathology:ISBN 0-397-51047-0]
is_a: MT:0002932 ! joint morphology

[Term]
id: MT:0005246
name: orbit morphology
namespace: Trait.ontology
def: "structural anomaly of the contents of the bony cavity that contains the eyeball or of any of the parts of eight bones in the mouse which form the cavity" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal orbit" EXACT []
synonym: "orbit abnormalities" EXACT []
is_a: MT:0002092 ! eye morphology

[Term]
id: MT:0005247
name: extraocular muscle morphology
namespace: Trait.ontology
def: "structural anomaly of any of the striated muscles that move the eye and include: superior rectus, inferior rectus, medial rectus, lateral rectus, superior oblique, inferior oblique, retractor bulbi" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0000759 ! skeletal muscle morphology
is_a: MT:0003686 ! eye muscle morphology

[Term]
id: MT:0005248
name: Harderian gland morphology
namespace: Trait.ontology
def: "structural anomaly of the sebaceous gland located behind the eyeball in the orbit that excretes fluid that facilitates movement of the third eyelid" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "Harderian gland abnormalities" EXACT []
is_a: MT:0002163 ! gland morphology
is_a: MT:0005246 ! orbit morphology

[Term]
id: MT:0005249
name: palatine bone morphology
namespace: Trait.ontology
def: "any structural anomaly of either of two irregularly shaped bones that form the back of the hard palate and helps to form the nasal cavity and the floor of the orbits" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal hard palate" EXACT []
synonym: "abnormal palatine bone" EXACT []
is_a: MT:0005274 ! viscerocranium morphology
is_a: MT:0005552 ! orbital bone morphology

[Term]
id: MT:0005250
name: Sertoli cell number
namespace: Trait.ontology
def: "decreased number of cells of the seminiferous tubules that create the blood-testes barrier and enable spermatogenesis" [J:70212, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "decreased sertoli cell number" EXACT []
is_a: MT:0001940 ! testicular cell number
is_a: MT:0002784 ! Sertoli cell morphology
is_a: MT:0004109 ! Sertoli cell development

[Term]
id: MT:0005251
name: blepharitis
namespace: Trait.ontology
def: "inflammation of the eyelids" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "inflamed eyelids" EXACT []
is_a: MT:0001340 ! eyelid morphology
is_a: MT:0001851 ! eye inflammation

[Term]
id: MT:0005252
name: meibomian gland morphology
namespace: Trait.ontology
def: "structural anomaly of the sebaceous glands embedded in the tarsal plate of each eyelid" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001340 ! eyelid morphology
is_a: MT:0002163 ! gland morphology

[Term]
id: MT:0005253
name: eye physiology
namespace: Trait.ontology
def: "anomalous function and/or activity of the ocular system or any of its parts" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0005391 ! vision/eye trait

[Term]
id: MT:0005254
name: strabismus
namespace: Trait.ontology
def: "misalignment of the visual axes of the eyes" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002092 ! eye morphology

[Term]
id: MT:0005255
name: exotropia
namespace: Trait.ontology
def: "a form of ocular misalignment in which the lateral rectus muscle pulls the eye in an outward direction" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0005254 ! strabismus

[Term]
id: MT:0005256
name: esotropia
namespace: Trait.ontology
def: "a form of ocular misalignment in which there is excessive convergence of the visual axes, giving a cross-eyed appearance" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "cross eyed" EXACT []
is_a: MT:0005254 ! strabismus

[Term]
id: MT:0005257
name: intraocular pressure
namespace: Trait.ontology
def: "anomaly in the amount of force per unit area exerted by the intraocular fluid within the eye" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005253 ! eye physiology

[Term]
id: MT:0005261
name: aniridia
namespace: Trait.ontology
def: "abnormality in which there is only a rudimentary iris, due to the failure of optic cup growth" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0001286 ! eye development

[Term]
id: MT:0005262
name: coloboma
namespace: Trait.ontology
def: "anomaly in which some of the structures of the eye are absent due to incomplete fusion of the fetal intraocular fissure during gestation" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0001286 ! eye development

[Term]
id: MT:0005263
name: ectopia lentis
namespace: Trait.ontology
def: "congenital displacement of the lens due to defective zonule formation" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "lens displacement" EXACT []
is_a: MT:0001286 ! eye development
is_a: MT:0001303 ! lens morphology

[Term]
id: MT:0005264
name: glomerulosclerosis
namespace: Trait.ontology
def: "hyaline deposits or scarring within the renal glomeruli, often occurring with renal arteriosclerosis or diabetes" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "glomerular sclerosis" EXACT []
is_a: MT:0000523 ! cortical glomerulopathies

[Term]
id: MT:0005265
name: blood urea nitrogen level
namespace: Trait.ontology
def: "aberrant circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal blood urea nitrogen" EXACT []
synonym: "abnormal BUN" EXACT []
is_a: MT:0000179 ! blood chemistry

[Term]
id: MT:0005267
name: olfactory cortex morphology
namespace: Trait.ontology
def: "anomalous structure of piriform cortex, part of the olfactory tract, which receives its major afferents from the olfactory bulb, and is primarily responsible for the identification of odors" [J:83884, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal olfactory cortex" EXACT []
synonym: "abnormal piriform area" EXACT []
synonym: "abnormal piriform cortex" EXACT []
is_a: MT:0005235 ! olfactory pathway morphology

[Term]
id: MT:0005269
name: occipital bone morphology
namespace: Trait.ontology
def: "anomalous structure of the bone at the lower, posterior part of the skull" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal occipital bone" EXACT []
is_a: MT:0000076 ! calvaria morphology
is_a: MT:0005273 ! cranial base morphology

[Term]
id: MT:0005270
name: zygomatic bone morphology
namespace: Trait.ontology
def: "any structural anomaly of the quadrilateral bone that forms the prominence of the cheek" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal cheek bone" EXACT []
synonym: "abnormal jugal bone" EXACT []
synonym: "abnormal malar bone" EXACT []
synonym: "abnormal yoke bone" EXACT []
synonym: "abnormal zygomatic bone" EXACT []
is_a: MT:0005274 ! viscerocranium morphology
is_a: MT:0005552 ! orbital bone morphology

[Term]
id: MT:0005271
name: lacrimal bone morphology
namespace: Trait.ontology
def: "anomalous structure of the irregularly thin plate that forms part of the medial wall of the orbit behind the frontal process of the maxilla" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal lacrimal bone" EXACT []
is_a: MT:0005274 ! viscerocranium morphology
is_a: MT:0005552 ! orbital bone morphology

[Term]
id: MT:0005272
name: temporal bone morphology
namespace: Trait.ontology
def: "anomalous structure of the large, irregular bone located at the base and side of the skull; consists of three parts at birth: squamous, tympanic, and petrous" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal squamosal bone" EXACT []
synonym: "abnormal temporal bone" EXACT []
is_a: MT:0000076 ! calvaria morphology
is_a: MT:0005552 ! orbital bone morphology

[Term]
id: MT:0005273
name: cranial base morphology
namespace: Trait.ontology
def: "anomalous structure or formation of the bones that form the floor of the cranial cavity" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal base of skull" EXACT []
synonym: "abnormal basicranium morphology" EXACT []
synonym: "abnormal basis cranii" RELATED []
synonym: "abnormal cranial base" EXACT []
is_a: MT:0000074 ! neurocranium morphology

[Term]
id: MT:0005274
name: viscerocranium morphology
namespace: Trait.ontology
def: "anomalous structure or formation of the part of the skull that comprises the facial bones " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal facial bones" EXACT []
synonym: "abnormal viscerocranium" EXACT []
is_a: MT:0000438 ! skull morphology

[Term]
id: MT:0005275
name: skin tensile strength
namespace: Trait.ontology
def: "change from the normal maximum tension the skin can withstand without tearing" [J:84062, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001191 ! skin condition

[Term]
id: MT:0005276
name: skin tumor
namespace: Trait.ontology
def: "presence of abnormal rapidly proliferating cells in the dermis and/or epidermis, usually in the form of a distinct mass" [J:73649, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001191 ! skin condition
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0005277
name: brainstem morphology
namespace: Trait.ontology
def: "anomalous structure of the midbrain, pons, or medulla" [J:82670, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "abnormal brain stem" EXACT []
synonym: "abnormal brainstem" EXACT []
is_a: MT:0002152 ! brain morphology

[Term]
id: MT:0005278
name: cholesterol homeostasis
namespace: Trait.ontology
def: "anomaly in the state of equilibrium in the body of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [J:71350, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
subset: slim_pig
is_a: MT:0002118 ! lipid homeostasis

[Term]
id: MT:0005280
name: fatty acid level
namespace: Trait.ontology
def: "anomalous concentration of organic, monobasic acids derived from hydrocarbons and which are complexed with serum albumin for transport; they are saturated and unsaturated" [MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_cattle
subset: slim_pig
is_a: MT:0001547 ! lipid level
relationship: part_of MT:0005666 ! adipose tissue physiology

[Term]
id: MT:0005285
name: unsaturated fatty acid level
namespace: Trait.ontology
def: "less than normal non-circulating level of organic, monobasic acids derived from hydrocarbons in which the carbon chain has one or more double or triple carbon-carbon bonds" [MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_pig
synonym: "lowered unsaturated fatty acid level" EXACT []
is_a: MT:0005280 ! fatty acid level

[Term]
id: MT:0005286
name: saturated fatty acid level
namespace: Trait.ontology
def: "less than normal non-circulating level of organic, monobasic acids derived from hydrocarbons in which the carbon chain contains only single carbon-carbon bonds" [MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_pig
synonym: "lowered saturated fatty acid level" EXACT []
is_a: MT:0005280 ! fatty acid level

[Term]
id: MT:0005288
name: oxygen consumption rate
namespace: Trait.ontology
def: "deviation from the normal rate at which oxygen enters the blood from alveolar gas; this is equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal metabolic rate" EXACT []
is_a: MT:0003948 ! gas homeostasis

[Term]
id: MT:0005291
name: glucose tolerance
namespace: Trait.ontology
def: "deviation from the normal response to oral consumption or intravenous injection of specified amounts of glucose; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002078 ! glucose homeostasis

[Term]
id: MT:0005294
name: heart ventricle morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the lower chamber(s) of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
subset: slim_chkn
synonym: "cardiac ventricle morphology" RELATED []
synonym: "cardiac ventricular morphology" RELATED []
synonym: "heart ventricular morphology" EXACT []
relationship: part_of MT:0000266 ! cardiac morphology

[Term]
id: MT:0005295
name: left ventricle integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the left lower chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0000053 ! heart integrity
relationship: part_of MT:0003921 ! left ventricle morphology

[Term]
id: MT:0005296
name: humerus morphology
namespace: Trait.ontology
def: "malformation of the bone of the forelimb that articulates with the scapula above and the radius and ulna below" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
synonym: "abnormal humerus" EXACT []
is_a: MT:0003723 ! long bone morphology

[Term]
id: MT:0005297
name: spina bifida occulta
namespace: Trait.ontology
def: "common congenital midline defect of fusion of the vertebral arch without protrusion of the spinal cord or meninges" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "closed spinal bifida" EXACT []
synonym: "occult spina bifida" EXACT []
is_a: MT:0003054 ! spina bifida

[Term]
id: MT:0005298
name: clavicle morphology
namespace: Trait.ontology
def: "malformation of the doubly curved long bone that forms part of the shoulder girdle and articulates with the sternum and the scapula" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal clavicle" EXACT []
synonym: "abnormal collar bone" EXACT []
is_a: MT:0000148 ! shoulder/ pelvic girdle morphology

[Term]
id: MT:0005299
name: eye posterior chamber
namespace: Trait.ontology
def: "anomaly of the ring-like space, filled with aqueous humor, between the iris/pupil anteriorly and the lens and ciliary body posteriorly" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "eye posterior chamber abnormalities" EXACT []
is_a: MT:0005193 ! anterior eye segment morphology

[Term]
id: MT:0005300
name: corneal stroma morphology
namespace: Trait.ontology
def: "structural anomaly of the lamellated connective tissue of the cornea" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001312 ! cornea morphology

[Term]
id: MT:0005301
name: corneal endothelium morphology
namespace: Trait.ontology
def: "anomalous structure of the single layer of large flattened cells that cover the surface of the cornea" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0001312 ! cornea morphology

[Term]
id: MT:0005302
name: neurogenic bladder
namespace: Trait.ontology
def: "defective functioning of the bladder due to impaired innervation, either within the CNS or the PNS" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "neuropathic bladder" EXACT []
is_a: MT:0002184 ! innervation
is_a: MT:0005303 ! urinary bladder physiology

[Term]
id: MT:0005303
name: urinary bladder physiology
namespace: Trait.ontology
def: "abnormal working of the inflatable musculomembranous bag for holding urine" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "urinary bladder dysfunction" EXACT []
is_a: MT:0001756 ! urination

[Term]
id: MT:0005304
name: cystic bulbourethral gland
namespace: Trait.ontology
def: "presence of membrane-lined sacs containing gas, fluid, or semisolid matter in the gland in males that lies along the prostate gland and secretes a fluid component of the seminal fluid into the urethra" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "cystic Cowper's gland" EXACT []
is_a: MT:0001169 ! bulbourethral gland morphology

[Term]
id: MT:0005305
name: coagulating gland size
namespace: Trait.ontology
def: "increased number of normal cells in the anterior lobe of the prostate" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "hyperplastic coagulating gland" EXACT []
is_a: MT:0001163 ! coagulating gland morphology

[Term]
id: MT:0005306
name: phalanx morphology
namespace: Trait.ontology
def: "aberrant structure of any of the long bones of the digits" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal phalanges" EXACT []
synonym: "abnormal phalanxes" EXACT []
is_a: MT:0002115 ! skeleton extremities morphology

[Term]
id: MT:0005308
name: circulating ammonia level
namespace: Trait.ontology
def: "aberrant concentration in the blood of this colorless alkaline gas, formed in the body during organic decomposition" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal ammonia level" EXACT []
is_a: MT:0000179 ! blood chemistry

[Term]
id: MT:0005310
name: salivary gland physiology
namespace: Trait.ontology
def: "anomalous function of any of the glands in the mouth that secrete saliva" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal salivary gland function" EXACT []
is_a: MT:0001663 ! digestive system physiology
is_a: MT:0002164 ! gland physiology

[Term]
id: MT:0005311
name: circulating amino acid level
namespace: Trait.ontology
def: "aberrant concentration in the blood of these organic compounds, which, when polymerized, form proteins" [J:83263, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal blood amino acid level" EXACT []
is_a: MT:0000179 ! blood chemistry
is_a: MT:0005332 ! amino acid level

[Term]
id: MT:0005316
name: response to tactile stimuli
namespace: Trait.ontology
is_a: MT:0002734 ! mechanical nociception

[Term]
id: MT:0005319
name: enzyme/ coenzyme level
namespace: Trait.ontology
def: "altered concentration of any of these proteins, or their cofactors, that act as catalysts to induce chemical changes in other substances" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
subset: slim_pig
is_a: MT:0001764 ! homeostasis

[Term]
id: MT:0005320
name: biopterin level
namespace: Trait.ontology
def: "anomalous concentration of this pterin found in yeast, the fruit fly and in normal human urine, the reduced form of which acts as a coenzyme for many enzymatic reactions" [J:84533, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005319 ! enzyme/ coenzyme level

[Term]
id: MT:0005321
name: neopterin level
namespace: Trait.ontology
def: "anomalous concentration of this pteridine derivative, which is present in body fluids and is a precursor in the biosynthesis of biopterin; elevated levels result from immune activation, malignant disease, allograft rejection, and viral infection" [J:84533, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005320 ! biopterin level

[Term]
id: MT:0005322
name: serotonin level
namespace: Trait.ontology
def: "anomalous concentration of biochemical messenger and regulator, found in the CNS, gastrointestinal tract, and produced by platelets; it mediates neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity" [ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition"]
synonym: "5-HT level" EXACT []
is_a: MT:0002504 ! serotonin activity

[Term]
id: MT:0005324
name: ascites
namespace: Trait.ontology
def: "accumulation or retention of fluid within the peritoneal cavity" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001784 ! fluid regulation

[Term]
id: MT:0005325
name: glomerulus morphology
namespace: Trait.ontology
def: "anomalous structure of the capillary loops of the kidney that normally function as a filtration unit" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:57971]
synonym: "abnormal glomerular capillaries" EXACT []
synonym: "abnormal glomeruli" EXACT []
is_a: MT:0002827 ! renal corpuscle morphology

[Term]
id: MT:0005326
name: podocyte morphology
namespace: Trait.ontology
def: "anomalous structure of the foot processes of the epithelial cells of the glomerulus" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:57971]
synonym: "abnormal glomerular epithelial cells" EXACT []
is_a: MT:0005325 ! glomerulus morphology

[Term]
id: MT:0005327
name: mesangial cell morphology
namespace: Trait.ontology
def: "anomalous structure of the phagocytic cell in the capillary tuft of the renal glomerulus, interposed between endothelial cells and the basement membrane in the central or stalk region of the tuft" [J:57971, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal deep cell" EXACT []
synonym: "abnormal intercapillary cell" EXACT []
is_a: MT:0005325 ! glomerulus morphology

[Term]
id: MT:0005328
name: circulating creatinine level
namespace: Trait.ontology
def: "anomalous blood concentration of this product of creatine catabolism; abnormal levels indicative of renal dysfunction" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal creatinine level" EXACT []
is_a: MT:0000179 ! blood chemistry

[Term]
id: MT:0005329
name: heart muscle morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the involuntary muscle comprising the myocardium" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "cardiac muscle morphology" RELATED []
synonym: "myocardial morphology" RELATED []
xref: MP:0005329
is_a: MT:0002108 ! muscle morphology
relationship: part_of MT:0000266 ! cardiac morphology

[Term]
id: MT:0005332
name: amino acid level
namespace: Trait.ontology
def: "aberrant concentration of these organic compounds, which, when polymerized, form proteins" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0001764 ! homeostasis

[Term]
id: MT:0005334
name: fat pad morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the encapsulated adipose tissue" [CP:Cari Park_Iowa State University curator]
subset: slim_chkn
is_a: MT:0000003 ! adipose tissue morphology

[Term]
id: MT:0005335
name: gonadal fat pad morphology
namespace: Trait.ontology
is_a: MT:0005334 ! fat pad morphology

[Term]
id: MT:0005336
name: inguinal fat pad morphology
namespace: Trait.ontology
is_a: MT:0005334 ! fat pad morphology

[Term]
id: MT:0005337
name: retroperitoneal fat pad morphology
namespace: Trait.ontology
is_a: MT:0005334 ! fat pad morphology

[Term]
id: MT:0005342
name: lipid absorption
namespace: Trait.ontology
def: "anomalous ability of the body to take in fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water" [J:85204, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
is_a: MT:0001666 ! nutrient absorption
is_a: MT:0002118 ! lipid homeostasis

[Term]
id: MT:0005345
name: circulating corticosterone level
namespace: Trait.ontology
def: "anomalous blood concentration of this adrenocortical steroid; induces glycogen deposition and regulates sodium conservation and potassium secretion" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_chkn
synonym: "abnormal serum level of corticosterone" EXACT []
is_a: MT:0003366 ! circulating glucocorticoid level
is_a: MT:0003963 ! corticosterone level

[Term]
id: MT:0005346
name: circulating aldosterone level
namespace: Trait.ontology
def: "anomalous blood concentration of this hormone, secreted by the adrenal cortex, in the bloodstream; regulates sodium conservation and potassium secretion in the distal renal tubule" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal serum level of aldosterone" EXACT []
is_a: MT:0005418 ! circulating hormone level

[Term]
id: MT:0005349
name: IL-6 physiology
namespace: Trait.ontology
def: "functional anomaly of this soluble factor produced by B- and T-cells, with effects on T- and B-cell growth and differentiation, and in acute phase reactions" [Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
is_a: MT:0002529 ! interleukin physiology

[Term]
id: MT:0005353
name: patella morphology
namespace: Trait.ontology
def: "anomalous structure of the large sesamoid bone that covers the anterior surface of the knee" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:47316, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal kneecap" EXACT []
synonym: "abnormal patella" EXACT []
is_a: MT:0002115 ! skeleton extremities morphology

[Term]
id: MT:0005354
name: ilium morphology
namespace: Trait.ontology
def: "structural anomaly of the broad, flaring portion of the hip bone, which is distinct at birth, but later fuses with the ischium and the pubis " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:47316, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal iliac bone" EXACT []
synonym: "abnormal ilium" EXACT []
is_a: MT:0000148 ! shoulder/ pelvic girdle morphology

[Term]
id: MT:0005355
name: thyroid gland size
namespace: Trait.ontology
def: "increased size of the endocrine gland located in the front and to the sides of the upper part of the trachea, and which secretes thyroid hormone and calcitonin " [J:85158, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000681 ! thyroid gland morphology

[Term]
id: MT:0005357
name: locomotor activation in a new environment
namespace: Trait.ontology
subset: slim_pig
synonym: "locomotion" RELATED []
is_a: MT:0001413 ! response to new environment
is_a: MT:0003313 ! locomotor activation

[Term]
id: MT:0005358
name: incisor morphology
namespace: Trait.ontology
def: "structural defect of the long pointed teeth; most anterior and prominent in the jaw" [J:85574, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "abnormal incisors" EXACT []
is_a: MT:0002100 ! tooth morphology

[Term]
id: MT:0005359
name: growth of incisors
namespace: Trait.ontology
def: "developmental delay of the growth of the incisors, the long pointed teeth, most anterior and prominent in the jaw " [J:85574, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
is_a: MT:0000116 ! tooth development

[Term]
id: MT:0005360
name: urolithiasis
namespace: Trait.ontology
def: "presence of calculi in any part of the urinary system" [J:85461, J:85462, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005502 ! urinary system physiology

[Term]
id: MT:0005361
name: pituitary gland size
namespace: Trait.ontology
def: "reduced size of the pituitary gland, the compound gland suspended from the base of the hypothalamus, which secretes somatotropins, prolactin, TSH (thyroid-stimulating hormone), gonadotropins, adrenal corticotropin" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0000633 ! pituitary gland morphology

[Term]
id: MT:0005362
name: Langerhans cell physiology
namespace: Trait.ontology
def: "atypical or failure of normal function of the phagocytic dendritic cells principally found in the epidermis" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "abnormal Langerhans cell function" EXACT []
is_a: MT:0002376 ! dendritic cell physiology

[Term]
id: MT:0005363
name: susceptibility to prion infection
namespace: Trait.ontology
alt_id: MT:0003003
def: "reduced likelihood that an organism will develop ill effects from the small proteinaceous infectious particles which are resistant to inactivation by procedures that modify nucleic acids and which contain an abnormal isoform of a cellular protein that is a major and necessary component" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "resistance to prion infection" EXACT []
is_a: MT:0001793 ! susceptibility to infection

[Term]
id: MT:0005365
name: bile salt homeostasis
namespace: Trait.ontology
def: "anomalous regulation of the steroid salts derived from cholesterol in the liver and which play an important role in the digestion and absorption of fats" [J:86154, MeSH:National Library of Medicine_Medical Subject Headings, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
is_a: MT:0001764 ! homeostasis

[Term]
id: MT:0005366
name: variegated coat color
namespace: Trait.ontology
def: "dappled coloration of the fur; mosaic" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
synonym: "variegated or mosaic" EXACT []
is_a: MT:0000372 ! irregular coat pigmentation

[Term]
id: MT:0005367
name: renal/urinary system trait
namespace: Trait.ontology
synonym: "kidney" EXACT []
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005369
name: muscle trait
namespace: Trait.ontology
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005370
name: liver/biliary system trait
namespace: Trait.ontology
subset: slim_chkn
subset: slim_pig
synonym: "hepatic" EXACT []
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005371
name: limbs/digits/tail trait
namespace: Trait.ontology
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005372
name: life span/aging trait
namespace: Trait.ontology
subset: slim_cattle
subset: slim_pig
synonym: "lifespan" EXACT []
synonym: "survival" EXACT []
synonym: "viability" EXACT []
synonym: "viable" EXACT []
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005375
name: adipose tissue trait
namespace: Trait.ontology
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "fat" EXACT []
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005376
name: homeostasis/metabolism trait
namespace: Trait.ontology
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005377
name: hearing/vestibular/ear trait
namespace: Trait.ontology
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005378
name: growth/size trait
namespace: Trait.ontology
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005379
name: endocrine/exocrine gland trait
namespace: Trait.ontology
subset: slim_cattle
subset: slim_pig
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005380
name: embryogenesis trait
namespace: Trait.ontology
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005381
name: digestive/alimentary trait
namespace: Trait.ontology
subset: slim_chkn
subset: slim_pig
synonym: "gastrointestinal" EXACT []
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005382
name: craniofacial trait
namespace: Trait.ontology
subset: slim_pig
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005384
name: cellular trait
namespace: Trait.ontology
synonym: "cell" EXACT []
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005385
name: cardiovascular system trait
namespace: Trait.ontology
def: "any measurable or observable characterisitic of the heart and/or vasculature" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
subset: slim_chkn
subset: slim_pig
synonym: "cardiac" EXACT []
synonym: "circulatory" EXACT []
synonym: "heart" EXACT []
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005386
name: behavior/neurological trait
namespace: Trait.ontology
alt_id: MT:0001350
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005387
name: immune system trait
namespace: Trait.ontology
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005388
name: respiratory system trait
namespace: Trait.ontology
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "lung" EXACT []
synonym: "pulmonary" EXACT []
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005389
name: reproductive system trait
namespace: Trait.ontology
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "reproduction" EXACT []
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005390
name: skeleton trait
namespace: Trait.ontology
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "bone" EXACT []
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005391
name: vision/eye trait
namespace: Trait.ontology
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005392
name: touch/vibrissae trait
namespace: Trait.ontology
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005393
name: skin/coat/nails/feathers trait
namespace: Trait.ontology
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005394
name: taste/olfaction trait
namespace: Trait.ontology
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005395
name: other trait
namespace: Trait.ontology
subset: slim_cattle
subset: slim_pig
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005397
name: hematopoietic system trait
namespace: Trait.ontology
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "hemopoietic system phenotype" EXACT []
is_a: MT:0000001 ! Trait

[Term]
id: MT:0005398
name: susceptibility to fungal infection
namespace: Trait.ontology
def: "reduced likelihood that an organism will develop ill effects from infection by a yeast or mold, or from components of, or toxins produced by, these organisms " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "decreased susceptibility to mold infection" EXACT []
synonym: "decreased susceptibility to yeast infection" EXACT []
is_a: MT:0001793 ! susceptibility to infection

[Term]
id: MT:0005400
name: vitamin level
namespace: Trait.ontology
def: "anomalous concentration of any of the organic substances found in food that are necessary in trace amounts for normal metabolic function" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0004019 ! vitamin homeostasis

[Term]
id: MT:0005401
name: fat-soluble vitamin level
namespace: Trait.ontology
def: "anomalous concentration of any of the organic substances found in food that are necessary in trace amounts for normal metabolic function and which require the presence of lipids for assimilation in the body" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0005400 ! vitamin level

[Term]
id: MT:0005402
name: action potential
namespace: Trait.ontology
def: "change in the electric response of a nerve or other excitable tissue to its stimulation" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0002272 ! nervous system electrophysiology

[Term]
id: MT:0005403
name: nerve conduction
namespace: Trait.ontology
def: "anomaly in the act of transmitting electricity along a single nerve" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002272 ! nervous system electrophysiology

[Term]
id: MT:0005404
name: axon morphology
namespace: Trait.ontology
def: "anomaly in the structure of the single process of a nerve cell that normally conducts impulses away from the cell body" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002882 ! neuron

[Term]
id: MT:0005405
name: axon integrity
namespace: Trait.ontology
def: "retrogressive pathologic change in the single process of a nerve cell " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000958 ! peripheral nervous system integrity
is_a: MT:0002229 ! neural integrity

[Term]
id: MT:0005406
name: heart size
namespace: Trait.ontology
def: "the physical dimensions, proportions, magnitude, or extent of the cardiac muscle or any of its component structures" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
subset: slim_chkn
subset: slim_pig
synonym: "cardiac size" RELATED []
relationship: part_of MT:0000266 ! cardiac morphology

[Term]
id: MT:0005409
name: coat color intensity
namespace: Trait.ontology
def: "amount and distribution of yellow pigment (phaeomelanin) relative to black or brown pigment (eumelanin) is decreased when compared to wild-type agouti" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0002075 ! coat color

[Term]
id: MT:0005410
name: fertilization
namespace: Trait.ontology
def: "anomaly in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronuclei" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_chkn
is_a: MT:0001919 ! reproductive system physiology

[Term]
id: MT:0005411
name: onset of fertilization
namespace: Trait.ontology
def: "a lag in the normal time of onset of the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronuclei" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005410 ! fertilization

[Term]
id: MT:0005412
name: blood vessel patency
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the openness of the tubes that carry blood through the body" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "vascular patency" RELATED []
relationship: part_of MT:0000088 ! blood vessel integrity

[Term]
id: MT:0005414
name: extrahepatic cholestasis
namespace: Trait.ontology
def: "impairment of bile flow in the large bile ducts by mechanical obstruction or stricture due to benign or malignant process" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "extrahepatic bile duct obstruction" EXACT []
synonym: "extrahepatic bile stasis" EXACT []
synonym: "extrahepatic biliary stasis" EXACT []
is_a: MT:0000610 ! cholestasis

[Term]
id: MT:0005415
name: intrahepatic cholestasis
namespace: Trait.ontology
def: "impairment of bile flow due to injury to the hepatocytes, bile canaliculi, or the intrahepatic bile ducts" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "intrahepatic bile duct obstruction" EXACT []
synonym: "intrahepatic bile stasis" EXACT []
synonym: "intrahepatic biliary stasis" EXACT []
is_a: MT:0000610 ! cholestasis

[Term]
id: MT:0005416
name: circulating protein level
namespace: Trait.ontology
def: "anomalous blood concentration of any of the macromolecules consisting of long chains of amino acids in peptide linkage" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
subset: slim_pig
synonym: "abnormal protein level" EXACT []
is_a: MT:0000179 ! blood chemistry

[Term]
id: MT:0005418
name: circulating hormone level
namespace: Trait.ontology
def: "anomalous blood concentration of any of the chemical substances that have specific regulatory effects on the activity of a certain organ or organs; originally applied to substances secreted by various endocrine glands and transported in the bloodstream to the target organs, it is sometimes extended to include substances that are not produced by the endocrine glands but that have similar effects" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0000179 ! blood chemistry
is_a: MT:0003953 ! hormone level

[Term]
id: MT:0005421
name: loose skin
namespace: Trait.ontology
def: "condition in which the skin hangs in folds" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "cutis laxa" EXACT []
synonym: "dermatochalasis" EXACT []
is_a: MT:0001191 ! skin condition

[Term]
id: MT:0005422
name: osteosclerosis
namespace: Trait.ontology
def: "abnormal hardening or eburnation (change in exposed subchondral bone in degenerative joint disease in which bone is converted into a dense substance with a smooth surface) of bone " [cml:Cathleen M. Lutz_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "bone sclerosis" EXACT []
is_a: MT:0003795 ! bone structure

[Term]
id: MT:0005423
name: somatic nervous system physiology
namespace: Trait.ontology
def: "anomalous function of any of the cranial and spinal nerves or their ganglia or the peripheral sensory receptors" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0005424
name: body movement
namespace: Trait.ontology
is_a: MT:0001516 ! motor coordination/ balance

[Term]
id: MT:0005428
name: clinical chemistry
namespace: Trait.ontology
def: "any anomaly in the laboratory tests that show the presence of physiologically significant substances in the blood, urine, tissue, and body fluids with application to the diagnosis or therapy of disease" [MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0001764 ! homeostasis

[Term]
id: MT:0005429
name: pine bedding color after urinary excretion
namespace: Trait.ontology
def: "with normal urine coloration, a change in the hue of the pine bedding of a mouse, often to a bright yellow or chartreuse, after excretion of urine by the animal housed with this type of bedding; indicative of a metabolic defect" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0001757 ! urine chemistry

[Term]
id: MT:0005431
name: oocyte number
namespace: Trait.ontology
def: "reduced numbers or absence of germ cells in the female" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, llw2:Linda Washburn_Mouse Genome Informatics Curator]
synonym: "female germ cell depletion" EXACT []
is_a: MT:0002209 ! germ cell number

[Term]
id: MT:0005432
name: pro-B cell morphology/development
namespace: Trait.ontology
def: "anomalous structure, development, or number of cells in the developing B cell lineage that have displayed B cell surface markers, but have not yet completed heavy chain gene rearrangement" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "pro-B cell abnormalities" EXACT []
is_a: MT:0002144 ! B lymphocyte development

[Term]
id: MT:0005437
name: glycogen level
namespace: Trait.ontology
def: "anomalous concentration of this readily converted carbohydrate reserve, found in most tissues of the body, especially liver and muscle" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_pig
relationship: part_of ID:0000694 ! muscle glycogen homeostasis
relationship: part_of MT:0005438 ! glycogen homeostasis

[Term]
id: MT:0005438
name: glycogen homeostasis
namespace: Trait.ontology
def: "abnormal processing and or utilization of this readily converted carbohydrate reserve, found in most tissues of the body, especially liver and muscle" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_pig
is_a: MT:0002078 ! glucose homeostasis

[Term]
id: MT:0005442
name: pyramidal neuron morphology
namespace: Trait.ontology
def: "anomaly of the malformed projection neurons in the cerebral cortex and hippocampus" [MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal pyramidal cell" EXACT []
is_a: MT:0000788 ! cerebral cortex morphology
is_a: MT:0000807 ! hippocampus morphology
is_a: MT:0002882 ! neuron

[Term]
id: MT:0005443
name: ethanol metabolism
namespace: Trait.ontology
def: "altered ability to metabolize the clear, colorless liquid that is the primary ingredient in alcoholic beverages" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:55555, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal alcohol metabolism" EXACT []
is_a: MT:0002585 ! response/metabolism to xenobiotics

[Term]
id: MT:0005444
name: retinol metabolism
namespace: Trait.ontology
def: "altered ability to metabolize this organic compound that plays an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:55555, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0004019 ! vitamin homeostasis

[Term]
id: MT:0005445
name: neurotransmitter release
namespace: Trait.ontology
def: "aberration in the secretion of endogenous signaling molecules normally secreted by neurons that alter the behavior of neurons or effector cells" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002204 ! neurotransmitter level

[Term]
id: MT:0005446
name: synaptic epinephrine release
namespace: Trait.ontology
def: "aberrant secretion across synapses of the active sympathomimetic hormone that stimulates both the alpha- and beta- adrenergic systems, causes systemic vasoconstriction and gastrointestinal relaxation, stimulates the heart, and dilates bronchi and cerebral vessels" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal synaptic adrenaline release" EXACT []
is_a: MT:0005445 ! neurotransmitter release

[Term]
id: MT:0005447
name: synaptic norepinephrine release
namespace: Trait.ontology
def: "aberrant secretion across synapses of this widespread central and autonomic neurotransmitter, the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal synaptic norepinephrine release" EXACT []
is_a: MT:0005445 ! neurotransmitter release

[Term]
id: MT:0005448
name: energy balance
namespace: Trait.ontology
def: "aberrant intake or expenditure of calories as compared to the normal state" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002121 ! metabolism

[Term]
id: MT:0005449
name: food intake
namespace: Trait.ontology
subset: slim_cattle
subset: slim_pig
synonym: "feed consumption" EXACT []
synonym: "food consumption" EXACT []
is_a: MT:0001431 ! eating behavior

[Term]
id: MT:0005450
name: energy expenditure
namespace: Trait.ontology
def: "utilization of calories that differs from normal " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal energy metabolism" EXACT []
is_a: MT:0005448 ! energy balance

[Term]
id: MT:0005451
name: body composition
namespace: Trait.ontology
def: "anomalous relative amounts of various components of the body, such as percent body fat" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_pig
is_a: MT:0001764 ! homeostasis

[Term]
id: MT:0005452
name: body fat amount
namespace: Trait.ontology
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_a: MT:0000003 ! adipose tissue morphology

[Term]
id: MT:0005456
name: weight gain
namespace: Trait.ontology
def: "number of excess calories needed to increase body weight by a specified amount" [MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_cattle
subset: slim_pig
is_a: MT:0001259 ! body weight

[Term]
id: MT:0005457
name: percent body fat
namespace: Trait.ontology
is_a: MT:0005452 ! body fat amount

[Term]
id: MT:0005460
name: leukopoiesis
namespace: Trait.ontology
alt_id: MT:0002430
def: "anomalous process of generating white blood cells (leukocytes) from the pluripotent hematopoietic stem cells of the bone marrow; two significant pathways generate various types of leukocytes: myelopoiesis, in which leukocytes in the blood are derived from myeloid stem cells, and lymphopoiesis, in which leukocytes of the lymphatic system (lymphocytes) are generated from lymphoid stem cells" [MeSH:National Library of Medicine_Medical Subject Headings]
subset: slim_pig
synonym: "abnormal leukocyte morphology/development" EXACT []
synonym: "leukocyte abnormalities" EXACT []
synonym: "white blood cell abnormalities" EXACT []
is_a: MT:0002123 ! hematopoiesis
is_a: MT:0002449 ! immune cell development

[Term]
id: MT:0005461
name: dendritic cell morphology/development
namespace: Trait.ontology
def: "anomalous structure or atypical formation of the immunocompetent cells of the lymphoid and hemopoietic systems and skin, which function to process antigens and present them to T cells, thus stimulating cellular immunity" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0005460 ! leukopoiesis

[Term]
id: MT:0005462
name: mast cell morphology/development
namespace: Trait.ontology
def: "anomalous structure, development or number of the granulated cells found in most tissues and which contain large amounts of histamine and heparin in granules" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002422 ! basophil morphology/development

[Term]
id: MT:0005463
name: CD4+ T cell physiology
namespace: Trait.ontology
def: "anomalous response of the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
subset: slim_pig
synonym: "abnormal CD4+ T cell function" EXACT []
synonym: "CD4+ T cell dysfunction" EXACT []
is_a: MT:0002444 ! T cell physiology

[Term]
id: MT:0005464
name: platelet physiology
namespace: Trait.ontology
def: "atypical response of the non-nucleated cells found in the blood and involved in blood coagulation" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal platelet function" EXACT []
is_a: MT:0001545 ! hematopoietic system physiology
is_a: MT:0002551 ! blood coagulation

[Term]
id: MT:0005465
name: T helper 1 physiology
namespace: Trait.ontology
def: "anomalous response of the subset of helper T cells that enhance cell-mediated immune responses; these cells secrete IL-1 and gamma-IFN and are generally involved in inflammatory responses" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Immunobiology_The Immune System in Health and Disease:ISBN 0-8153-1691-7]
synonym: "abnormal T helper 1 function" EXACT []
synonym: "abnormal TH1 function" EXACT []
synonym: "abnormal Th1 function" EXACT []
is_a: MT:0005463 ! CD4+ T cell physiology

[Term]
id: MT:0005466
name: T helper 2 physiology
namespace: Trait.ontology
def: "anomalous response of the subset of T helper cells that enhance humoral immunity and inhibit cell-mediated immune responses; these cells produce IL-4 and induce B cells to produce IgE and IgG1, while also supporting eosinophil and mast cell functions" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "abnormal T helper 2 function" EXACT []
synonym: "abnormal TH2 function" EXACT []
synonym: "abnormal Th2 function" EXACT []
is_a: MT:0005463 ! CD4+ T cell physiology

[Term]
id: MT:0005467
name: chemotactic leukotriene physiology
namespace: Trait.ontology
def: "functional anomaly of any of a subset of leukotrienes that are involved in attracting leukocytes to a site of tissue injury" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0002522 ! chemotactic factor physiology

[Term]
id: MT:0005468
name: thyroid hormone level
namespace: Trait.ontology
def: "aberrant concentration of any of the hormones secreted by the thyroid gland" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:13923, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0003953 ! hormone level

[Term]
id: MT:0005469
name: thyroxine level
namespace: Trait.ontology
def: "anomalous concentration of the major hormone derived from the thyroid gland; it normally affects cellular metabolism" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:13923, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal T4 level" EXACT []
synonym: "abnormal thyroxin level" EXACT []
is_a: MT:0005468 ! thyroid hormone level

[Term]
id: MT:0005472
name: triiodothyronine level
namespace: Trait.ontology
def: "aberrant concentration of this hormone synthesized and secreted by the thyroid; normally, this is the main thyroid hormone used by the tissues" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal T3 level" EXACT []
is_a: MT:0005468 ! thyroid hormone level

[Term]
id: MT:0005475
name: circulating thryoxine level
namespace: Trait.ontology
def: "anomalous blood concentration of the major hormone derived from the thyroid gland; it normally affects cellular metabolism" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal circulating level of T4" EXACT []
synonym: "abnormal circulating level of thryoxin" EXACT []
synonym: "abnormal circulating level of thryoxine" EXACT []
is_a: MT:0005469 ! thyroxine level

[Term]
id: MT:0005476
name: circulating triiodothyronine level
namespace: Trait.ontology
def: "aberration in the blood concentration of this hormone synthesized and secreted by the thyroid; normally, this is the main thyroid hormone used by the tissues" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal circulating level of T3" EXACT []
synonym: "abnormal circulating level of triiodothyronine" EXACT []
is_a: MT:0003351 ! circulating levels of thyroid hormone
is_a: MT:0005472 ! triiodothyronine level

[Term]
id: MT:0005478
name: circulating thyroxine level
namespace: Trait.ontology
def: "less than the normal blood concentration of the major hormone derived from the thyroid gland; it normally affects cellular metabolism" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "decreased circulating level of T4" EXACT []
synonym: "decreased circulating level of thyroxin" EXACT []
synonym: "decreased circulating level of thyroxine" EXACT []
is_a: MT:0003351 ! circulating levels of thyroid hormone

[Term]
id: MT:0005481
name: chronic myelocytic leukemia
namespace: Trait.ontology
def: "a heterogeneous group of myeloproliferative disorders that may evolve into acute leukemia in late stages " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "chronic granulocytic leukemia" EXACT []
synonym: "chronic myelogenous leukemia" EXACT []
synonym: "chronic myeloid leukemia" EXACT []
synonym: "CML" EXACT []
is_a: MT:0002026 ! leukemia

[Term]
id: MT:0005488
name: bronchial epithelial cell number
namespace: Trait.ontology
def: "increased numbers of cells lining the inner surfaces of the bronchi" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002264 ! bronchus morphology

[Term]
id: MT:0005490
name: Clara cell number
namespace: Trait.ontology
def: "increased numbers of the rounded, club-shaped, nonciliated cells found between ciliated cells in bronchiolar epithelium" [J:48446, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002264 ! bronchus morphology

[Term]
id: MT:0005493
name: stomach epithelial cell number
namespace: Trait.ontology
synonym: "gastric epithelial hyperplasia" EXACT []
is_a: MT:0000471 ! stomach epithelium morphology

[Term]
id: MT:0005494
name: esophagogastric junction metaplasia
namespace: Trait.ontology
def: "conversion of one differentiated cell type to another differentiated cell type at the terminal end of the esophagus and beginning of the stomach" [J:48446, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "G-E junction metaplasia" EXACT []
is_a: MT:0000467 ! esophagus morphology
is_a: MT:0005213 ! gastric metaplasia

[Term]
id: MT:0005495
name: macrophage recruitment
namespace: Trait.ontology
def: "fewer than normal macrophages accumulate in a specific location in response to a wide variety of substances released at the sites of inflammatory reactions" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002451 ! macrophage physiology

[Term]
id: MT:0005497
name: optic nerve cupping
namespace: Trait.ontology
def: "concave shape of the nerve often as a result of the force of pressure from glaucoma" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "cupping of optic nerve" EXACT []
is_a: MT:0001330 ! optic nerve morphology

[Term]
id: MT:0005499
name: olfactory system morphology
namespace: Trait.ontology
def: "anomalous structure of the organs involved in smell" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0005394 ! taste/olfaction trait

[Term]
id: MT:0005500
name: gustatory system morphology
namespace: Trait.ontology
def: "structural anomaly of the organs involved in taste" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005394 ! taste/olfaction trait

[Term]
id: MT:0005501
name: skin physiology
namespace: Trait.ontology
def: "atypical function of the membranous protective covering of the body" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005393 ! skin/coat/nails/feathers trait

[Term]
id: MT:0005502
name: urinary system physiology
namespace: Trait.ontology
def: "functional anomaly of any of the organs involved in the production or excretion of urine" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
synonym: "abnormal urinary system function" EXACT []
is_a: MT:0005367 ! renal/urinary system trait

[Term]
id: MT:0005503
name: tendon morphology
namespace: Trait.ontology
def: "structural anomaly of the fibrous bands or cords of connective tissue at the ends of muscle fibers that attach muscles to bones and other structures" [J:45509, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0002108 ! muscle morphology
is_a: MT:0005508 ! skeleton morphology

[Term]
id: MT:0005504
name: ligament morphology
namespace: Trait.ontology
def: "structural anomaly of the flexible bands of fibrous tissue that connect the articular extremities of bones" [J:45509, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0005508 ! skeleton morphology

[Term]
id: MT:0005508
name: skeleton morphology
namespace: Trait.ontology
alt_id: MT:0000055
def: "malformation of the bony framework of the body in vertebrates" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
synonym: "abnormal bone/ skeleton" EXACT []
synonym: "bone/ skeletal abnormalities" EXACT []
is_a: MT:0005390 ! skeleton trait

[Term]
id: MT:0005509
name: tongue neoplasm
namespace: Trait.ontology
def: "new abnormal growth of the tongue" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0005511
name: susceptibility to tongue neoplasm
namespace: Trait.ontology
def: "reduced likelihood of developing an abnormal growth of tongue tissue" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
synonym: "resistance to tongue tumor" EXACT []
is_a: MT:0005514 ! susceptibility to tumor development

[Term]
id: MT:0005512
name: susceptibility to mammary neoplasm
namespace: Trait.ontology
def: "reduced likelihood of developing an abnormal growth of mammary tissue" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
synonym: "resistance to mammary tumor" EXACT []
is_a: MT:0005514 ! susceptibility to tumor development

[Term]
id: MT:0005513
name: susceptibility to liver neoplasm
namespace: Trait.ontology
def: "likelihood of developing an abnormal growth of liver tissue" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
synonym: "resistance to liver tumor" EXACT []
is_a: MT:0005514 ! susceptibility to tumor development

[Term]
id: MT:0005514
name: susceptibility to tumor development
namespace: Trait.ontology
def: "reduced likelihood of developing new abnormal growth of any tissue" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator, cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, RGD:Rat Genome Database submission]
synonym: "resistance to neoplasm development" EXACT []
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0005515
name: uveitis
namespace: Trait.ontology
def: "inflammation of part or all of the uvea, the middle (vascular) tunic of the eye, and commonly involving the other tunics (sclera and cornea, and the retina)" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
is_a: MT:0001851 ! eye inflammation
is_a: MT:0005197 ! uvea morphology

[Term]
id: MT:0005518
name: pancreas regeneration
namespace: Trait.ontology
def: "deviation from the normal ability of the pancreas to regenerate healthy tissue following injury" [RGD:Rat Genome Database submission]
is_a: MT:0002693 ! pancreas physiology

[Term]
id: MT:0005521
name: circulating atrial natriuretic factor level
namespace: Trait.ontology
def: "deviation from the normal concentration of this peptide hormone in the blood; it regulates the water-electrolyte balance and acts as a vasodilator" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
is_a: MT:0005418 ! circulating hormone level

[Term]
id: MT:0005524
name: renal plasma flow rate
namespace: Trait.ontology
def: "volume of plasma passing through the kidney per unit time" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0000233 ! blood flow velocity
is_a: MT:0002136 ! kidney physiology

[Term]
id: MT:0005529
name: renal vascular resistance
namespace: Trait.ontology
def: "force opposing blood flow in the kidney blood vessels" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0002136 ! kidney physiology
is_a: MT:0005532 ! vascular resistance

[Term]
id: MT:0005532
name: vascular resistance
namespace: Trait.ontology
def: "force opposing the flow of blood through a vascular bed; it is equal to the difference in blood pressure across the vascular bed divided by the cardiac output" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0002128 ! blood circulation

[Term]
id: MT:0005535
name: body temperature
namespace: Trait.ontology
def: "deviation in the level of heat natural to a living being" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, RGD:Rat Genome Database submission, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_pig
is_a: MT:0001764 ! homeostasis

[Term]
id: MT:0005537
name: cerebral aqueduct morphology
namespace: Trait.ontology
def: "anomalous structure of the channel in the mesencephalon that connects the third and fourth ventricles" [hdene:Howard Dene_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "abnormal aqueduct of Sylvius" EXACT []
is_a: MT:0000897 ! midbrain morphology

[Term]
id: MT:0005540
name: albumin excretion
namespace: Trait.ontology
def: "less than the normal amount of this protein voided by the kidneys" [RGD:Rat Genome Database submission]
is_a: MT:0005555 ! kidney excretion

[Term]
id: MT:0005541
name: iris stromal pigmentation
namespace: Trait.ontology
def: "anomalous coloring of the framework of the iris" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0005102 ! iris pigmentation
is_a: MT:0005208 ! iris stroma morphology

[Term]
id: MT:0005542
name: corneal vascularization
namespace: Trait.ontology
def: "formation of blood vessels in the cornea, which normally lacks vessels" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001312 ! cornea morphology

[Term]
id: MT:0005543
name: corneal thickness
namespace: Trait.ontology
def: "decreased thickness of the cornea, the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "thin cornea" EXACT []
is_a: MT:0001312 ! cornea morphology

[Term]
id: MT:0005544
name: corneal deposits
namespace: Trait.ontology
def: "accumulation of minerals, proteins, or other anomalous substances on the cornea" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0001312 ! cornea morphology

[Term]
id: MT:0005545
name: lens development
namespace: Trait.ontology
def: "aberrant formation of the transparent structure of the eye responsible for focusing light rays" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0001286 ! eye development
is_a: MT:0001303 ! lens morphology

[Term]
id: MT:0005546
name: choroidal vascularization
namespace: Trait.ontology
def: "new vessel development of the thin, highly vascularized membrane covering most of the posterior of the eye between the retina and the sclera" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0003710 ! vascularization

[Term]
id: MT:0005547
name: Muller cell morphology
namespace: Trait.ontology
def: "anomalous structure of the elongated neuroglial cells that traverse all the layers of the retina and that act as supporting elements" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal Muller fiber morphology" EXACT []
is_a: MT:0001325 ! retina morphology

[Term]
id: MT:0005548
name: retinal pigment epithelium size
namespace: Trait.ontology
def: "wasting or decreased size of the epithelial layer of the retina composed of cells containing pigment granules " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "atrophy of retinal pigment epithelium" EXACT []
is_a: MT:0005201 ! retinal pigment epithelium morphology

[Term]
id: MT:0005549
name: retinal pigment epithelium cell number
namespace: Trait.ontology
def: "increased numbers of cells in the epithelial layer of the retina composed of cells containing pigment granules " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
synonym: "hyperplasia of retinal pigment epithelium" EXACT []
is_a: MT:0005548 ! retinal pigment epithelium size

[Term]
id: MT:0005550
name: orbital hemorrhage
namespace: Trait.ontology
def: "escape of blood into the orbit " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0005246 ! orbit morphology

[Term]
id: MT:0005551
name: eye electrophysiology
namespace: Trait.ontology
def: "abnormal function of the eye as determined through electrophysiological recordings from single cells or summary recordings from multiple cells (e.g. electroretinogram)" [NMF:Stephanie Pretel_Neuroscience Mutagenesis Facility Curator]
is_a: MT:0005253 ! eye physiology

[Term]
id: MT:0005552
name: orbital bone morphology
namespace: Trait.ontology
def: "structural anomaly of the bony cavity that contains the eyeball and is formed by parts of eight bones in the mouse: maxilla, lacrimal, zygomatic, frontal, temporal, sphenoid, ethmoid, palatine " [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal orbital bones" EXACT []
is_a: MT:0000438 ! skull morphology

[Term]
id: MT:0005555
name: kidney excretion
namespace: Trait.ontology
def: "altered ability of the kidneys to void specific substances" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0003606 ! kidney function

[Term]
id: MT:0005556
name: kidney clearance
namespace: Trait.ontology
def: "altered ability of the kidneys to remove substances from the plasma for excretion in a specific period of time" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0003606 ! kidney function

[Term]
id: MT:0005558
name: creatinine clearance
namespace: Trait.ontology
def: "less than the normal amount of this creatine metabolite filtered by the kidneys in a specific period of time; indicative of kidney function" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, RGD:Rat Genome Database submission]
is_a: MT:0005556 ! kidney clearance

[Term]
id: MT:0005563
name: hemoglobin content
namespace: Trait.ontology
def: "deviation from the normal total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith_Mouse Genome Informatics Curator]
is_a: MT:0001588 ! hemoglobin

[Term]
id: MT:0005567
name: circulating total protein level
namespace: Trait.ontology
def: "less than the average total concentration of these macromolecules in the blood " [RGD:Rat Genome Database submission]
synonym: "decreased plasma total protein level" EXACT []
synonym: "decreased total protein level" EXACT []
is_a: MT:0005416 ! circulating protein level

[Term]
id: MT:0005570
name: sodium excretion
namespace: Trait.ontology
def: "less than the normal amount of this element voided by the kidneys in a specific period of time" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, RGD:Rat Genome Database submission]
is_a: MT:0005555 ! kidney excretion

[Term]
id: MT:0005572
name: breathing frequency
namespace: Trait.ontology
def: "deviation from the normal number of breaths in a given period of time" [RGD:Rat Genome Database submission]
is_a: MT:0001951 ! breathing

[Term]
id: MT:0005577
name: uterine prolapse
namespace: Trait.ontology
def: "downward movement, and possible external appearance, of the uterus through the vagina" [J:88284, MeSH:National Library of Medicine_Medical Subject Headings, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
is_a: MT:0001120 ! uterus morphology

[Term]
id: MT:0005578
name: teratozoospermia
namespace: Trait.ontology
def: "presence of malformed spermatozoa in the semen; malformations include the physical bending of the sperm to produce kinks or bends" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "teratospermia" EXACT []
is_a: MT:0001156 ! spermatogenesis
is_a: MT:0002208 ! germ cell morphology

[Term]
id: MT:0005580
name: periinsulitis
namespace: Trait.ontology
def: "early pancreatic infiltration of mononuclear cells around pancreatic Langerhans islets" [il:Ira Lu_Mouse Genome Informatics Curator, J:11442]
synonym: "peri-insulitis" EXACT []
synonym: "periinsulinitis" EXACT []
is_a: MT:0001869 ! pancreas inflammation

[Term]
id: MT:0005581
name: renin activity
namespace: Trait.ontology
def: "altered ability of this enzyme to cleave angiotensinogen and create angiotensin I" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
synonym: "abnormal angiotensinogenase activity" EXACT []
is_a: MT:0005584 ! enzyme/coenzyme activity

[Term]
id: MT:0005584
name: enzyme/coenzyme activity
namespace: Trait.ontology
def: "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002121 ! metabolism

[Term]
id: MT:0005587
name: Meckel's cartilage morphology
namespace: Trait.ontology
def: "formation or structure of this cartilage bar in the mandibular arch that forms a temporary supporting structure in the embryonic mandible; gives rise to middle ear bones and sphenomandibular and anterior malleolar ligaments" [J:17694, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "mandibular cartilage morphology" EXACT []
synonym: "Meckel cartilage morphology" EXACT []
is_a: MT:0000163 ! cartilage morphology
is_a: MT:0003935 ! craniofacial development
is_a: MT:0003938 ! ear development

[Term]
id: MT:0005592
name: blood vessel smooth muscle morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the nonstriated, involuntary muscle tissue of the blood vessels" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "vascular smooth muscle morphology" RELATED []
xref: MP:0005592
is_a: MT:0000767 ! smooth muscle morphology
relationship: part_of MT:0001614 ! blood vessel morphology

[Term]
id: MT:0005593
name: vascular smooth muscle contraction
namespace: Trait.ontology
def: "altered or unexpected constriction of the nonstriated, involuntary muscle tissue of the blood vessels" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
is_a: MT:0000740 ! smooth muscle contractility
is_a: MT:0005595 ! vascular smooth muscle physiology

[Term]
id: MT:0005594
name: vascular smooth muscle dilation
namespace: Trait.ontology
def: "altered or unexpected widening of the nonstriated, involuntary muscle tissue of the blood vessels" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
is_a: MT:0005595 ! vascular smooth muscle physiology

[Term]
id: MT:0005595
name: vascular smooth muscle physiology
namespace: Trait.ontology
def: "anomalous function of the nonstriated, involuntary muscle tissue of the blood vessels" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
is_a: MT:0002106 ! muscle physiology

[Term]
id: MT:0005597
name: susceptibility to type I hypersensitivity reaction
namespace: Trait.ontology
def: "less likelihood or resistance to developing a response manifested by localized or generalized reaction that occurs immediately (minutes) after exposure to an antigen to which the person/animal was previously sensitized; it is IgE-mediated, and mast cell activation and degranulation are hallmarks" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:68588, Pathology:ISBN 0-397-51047-0]
comment: examples: hay fever, asthma, anaphylaxis
synonym: "decreased susceptibility to anaphylaxis" EXACT []
synonym: "decreased susceptibility to immediate type hypersensitivity" EXACT []
is_a: MT:0002531 ! type I hypersensitivity reaction

[Term]
id: MT:0005598
name: ventricle muscle contractility
namespace: Trait.ontology
def: "ability of the heart ventricle muscle to shorten or to develop increased tension" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "ventricular muscle contractility" EXACT []
is_a: MT:0002972 ! cardiac muscle contractility

[Term]
id: MT:0005603
name: neuron size
namespace: Trait.ontology
def: "increased mass of any of the structural and functional units of the nervous system, which consist of the nerve cell body, the dendrites, and the axon" [RGD:Rat Genome Database submission, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "neuronal hypertrophy" EXACT []
is_a: MT:0002882 ! neuron

[Term]
id: MT:0005607
name: bleeding time
namespace: Trait.ontology
def: "less than the normal duration of blood flow after skin puncture; indicative of platelet and capillary function" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
is_a: MT:0002551 ! blood coagulation

[Term]
id: MT:0005608
name: heart interstices patency
namespace: Trait.ontology
def: "openness of the small spaces within the tissue of the heart" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "cardiac interstices patency" RELATED []
relationship: part_of MT:0000053 ! heart integrity

[Term]
id: MT:0005609
name: circulating antidiuretic hormone level
namespace: Trait.ontology
def: "deviation from the normal concentration of this peptide hormone in the blood; it is normally released by the neurohypophysis to control water metabolism and balance by regulating water loss; it also contracts smooth muscle" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
synonym: "abnormal circulating level of ADH" EXACT []
synonym: "abnormal circulating level of antidiuretic hormone" EXACT []
synonym: "abnormal circulating level of vasopressin" EXACT []
is_a: MT:0005418 ! circulating hormone level

[Term]
id: MT:0005612
name: susceptibility to type II hypersensitivity reaction
namespace: Trait.ontology
def: "less likelihood of or resistance to developing a response caused by an Ag-Ab reaction; antibodies are directly or indirectly cytotoxic to antigens on cell surfaces or in connective tissues; most often involves IgG and IgM; complement activation is usually involved" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology:ISBN 0-397-51047-0]
comment: examples: autoimmune diseases: autoimmune hemolytic anemias, antibody-dependent cellular cytotoxicity (ADCC), Goodpasture disease, myasthenia gravis, Graves disease, pemphigous, pemphigoid
synonym: "decreased susceptibility to antibody-mediated cellular toxicity" EXACT []
synonym: "decreased susceptibility to cytotoxic type hypersensitivity" EXACT []
is_a: MT:0002532 ! type II hypersensitivity reaction

[Term]
id: MT:0005614
name: susceptibility to type III hypersensitivity reaction
namespace: Trait.ontology
def: "less likelihood of or resistance to developing tissue injury mediated by immune complexes; generally involves immune complexes formed in the blood via Abs encountering circulating Ag; Ag-Ab complexes then deposit in tissues (especially blood vessels and glomeruli), induce complement activation, and result in tissue injury" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology:ISBN 0-397-51047-0]
comment: Examples: Autoimmune diseases: systemic lupus erythmatosus (SLE), rheumatoid arthritis, sjogren syndrome, scleroderma. glomerulonephritis
synonym: "decreased susceptibility to immune complex mediated hypersensitivity" EXACT []
is_a: MT:0002533 ! type III hypersensitivity reaction

[Term]
id: MT:0005616
name: susceptibility to type IV hypersensitivity reaction
namespace: Trait.ontology
def: "less likelihood of or resistance to developing an antigen-elicited cellular immune reaction that results in tissue damage, but does not require Ab participation; the response is seen at the area of contact" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Pathology:ISBN 0-397-51047-0]
comment: Examples: granulomatous diseases: tuberculosis, sarcoidosis. contact dermatitis: elicited by poison ivy, detergents, clothing, etc.
synonym: "decreased susceptibility to cell-mediated hypersensitivity" EXACT []
synonym: "decreased susceptibility to delayed type hypersensitivity" EXACT []
is_a: MT:0002534 ! type IV hypersensitivity reaction

[Term]
id: MT:0005618
name: potassium excretion
namespace: Trait.ontology
def: "less than the normal amount of this alkaline metallic element, the most abundant intracellular ion, voided by the kidneys" [MeSH:National Library of Medicine_Medical Subject Headings, RGD:Rat Genome Database submission]
is_a: MT:0005555 ! kidney excretion

[Term]
id: MT:0005620
name: muscle contractility
namespace: Trait.ontology
def: "aberrant ability of a muscle to shorten or to develop increased tension" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
subset: slim_chkn
is_a: MT:0002106 ! muscle physiology

[Term]
id: MT:0005621
name: cell physiology
namespace: Trait.ontology
def: "aberration in the vital processes of the cell " [hdene:Howard Dene_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005384 ! cellular trait

[Term]
id: MT:0005623
name: meninges morphology
namespace: Trait.ontology
def: "anomaly in any of the membranes covering the spinal cord and brain, including the dura mater (external), arachnoid (middle), and pia mater (internal)" [J:48079, smb:Susan M. Bello_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0000955 ! spinal cord morphology
is_a: MT:0002152 ! brain morphology

[Term]
id: MT:0005624
name: plasma anion gap
namespace: Trait.ontology
def: "measurement of the interval between the sum of routinely measured cations minus the sum of the routinely measured anions in the blood; the anion gap = (Na+ + K+) - (Cl- + HCO3-) where Na- is sodium, K+ is potassium, Cl- is chloride, and HCO3- is bicarbonate " [RGD:Rat Genome Database submission]
is_a: MT:0001765 ! ion homeostasis

[Term]
id: MT:0005629
name: lung weight
namespace: Trait.ontology
def: "any change from the normal state in the physical heaviness of the lung" [RGD:Rat Genome Database submission]
subset: slim_chkn
is_a: MT:0003641 ! lung size

[Term]
id: MT:0005636
name: mineral homeostasis
namespace: Trait.ontology
def: "anomaly in the state of equilibrium in the body with respect to any of the inorganic substance that have importance in body functions" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001764 ! homeostasis

[Term]
id: MT:0005637
name: iron homeostasis
namespace: Trait.ontology
def: "anomaly in the state of equilibrium in the body with respect to this metallic element that normally occurs in the heme of hemoglobin, myoglobin, transferrin, ferritin, and iron-containing porphyrins; it is an essential component of enzymes such as catalase, peroxidase, and various cytochromes" [J:64456, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0005636 ! mineral homeostasis

[Term]
id: MT:0005638
name: hemochromatosis
namespace: Trait.ontology
def: "disorder due to the deposition of hemosiderin in the parenchymal cells, causing tissue damage and dysfunction of the liver, pancreas, heart, and pituitary" [J:64456, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0001770 ! iron level

[Term]
id: MT:0005639
name: hemosiderosis
namespace: Trait.ontology
def: "condition in which there is a generalized increase in the iron stores of body tissues, particularly of liver and the reticuloendothelial system, without demonstrable tissue damage" [MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0001770 ! iron level

[Term]
id: MT:0005640
name: mean corpuscular hemoglobin concentration
namespace: Trait.ontology
def: "deviation from the normal Hgb/Hct; the average hemoglobin concentration in a given volume of packed red cells, calculated from the hemoglobin therein and the hematocrit, in erythrocyte indices" [J:8936, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
synonym: "abnormal MCHC" EXACT []
is_a: MT:0001588 ! hemoglobin

[Term]
id: MT:0005644
name: agonadal
namespace: Trait.ontology
def: "denoting the absence of gonads" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0002211 ! primary sex determination

[Term]
id: MT:0005645
name: hypothalamus physiology
namespace: Trait.ontology
def: "anomalous function of the ventral and medial region of the diencephalon forming the walls of the ventral half of the third ventricle, which is normally involved in the functions of the autonomic (visceral motor) nervous system and, through its vascular link with the anterior lobe of the pituitary gland, in endocrine mechanisms" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002164 ! gland physiology
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0005646
name: pituitary gland physiology
namespace: Trait.ontology
def: "anomalous function of this unpaired compound gland suspended from the base of the hypothalamus by a short extension of the infundibulum, the infundibular or pituitary stalk" [Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0002164 ! gland physiology

[Term]
id: MT:0005647
name: sex gland physiology
namespace: Trait.ontology
def: "anomalous function of any of the organized aggregations of cells that function as secretory or excretory organs and are associated with reproduction" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0001919 ! reproductive system physiology
is_a: MT:0002164 ! gland physiology

[Term]
id: MT:0005649
name: spleen neoplasm
namespace: Trait.ontology
def: "abnormal new cellular growth of the spleen" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:70407]
synonym: "neoplastic spleen" EXACT []
synonym: "spleen neoplasia" EXACT []
is_a: MT:0002019 ! tumor incidence
is_a: MT:0002225 ! spleen cellularity

[Term]
id: MT:0005650
name: limb bud morphology
namespace: Trait.ontology
def: "aberrant structure or development of any of the swellings on the trunk of the embryo that become limbs" [hdene:Howard Dene_Mouse Genome Informatics Curator, J:61460, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0006279 ! limb development

[Term]
id: MT:0005651
name: gonad rudiment morphology
namespace: Trait.ontology
def: "absence or structural anomaly of the undifferentiated mesoderm that gives rise to the gonads" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0002210 ! sex determination

[Term]
id: MT:0005652
name: sex reversal
namespace: Trait.ontology
def: "development of the reproductive system is inconsistent with the chromosomal sex" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0002210 ! sex determination

[Term]
id: MT:0005653
name: phototoxicity
namespace: Trait.ontology
def: "condition caused by overexposure to UV light or from the combination of exposure to specific wavelengths and a phototoxic substance" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:80519, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0001191 ! skin condition
is_a: MT:0002121 ! metabolism
is_a: MT:0005501 ! skin physiology

[Term]
id: MT:0005654
name: porphyria
namespace: Trait.ontology
def: "acquired or inherited group of disorders characterized by excessive production of porphyrins or their precursors; if acquired, it results from inhibition of enzymes in the heme metabolic pathway by drugs, toxins or abnormal metabolites" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0004147 ! porphyrin level

[Term]
id: MT:0005657
name: neural plate morphology
namespace: Trait.ontology
def: "malformation or absence of the flat, thickened layer of ectodermal cells in the neuroectodermal area of the embryo's dorsal surface that develops into the neural tube and neural crest" [hdene:Howard Dene_Mouse Genome Informatics Curator, J:68142, Stedman's Medical Dictionary_27th edition:ISBN 0-683-40008-8]
is_a: MT:0003861 ! nervous system development

[Term]
id: MT:0005658
name: susceptibility to diet-induced obesity
namespace: Trait.ontology
def: "probability of become excessively fat or to increase fat in the subcutaneous connective tissue as a result of consuming a diet geared to increase body fat " [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator]
is_a: MT:0005450 ! energy expenditure

[Term]
id: MT:0005660
name: circulating adrenaline level
namespace: Trait.ontology
def: "aberrant concentration in the blood of this catecholamine hormone that stimulates the adrenergic receptors and that causes systemic vasoconstriction and gastrointestinal relaxation, stimulates the heart, and dilates bronchi and cerebral vessels" [MeSH:National Library of Medicine_Medical Subject Headings, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
is_a: MT:0003962 ! adrenaline level
is_a: MT:0005418 ! circulating hormone level

[Term]
id: MT:0005663
name: circulating noradrenaline level
namespace: Trait.ontology
def: "aberrant blood concentration of this precursor of epinephrine that is a widespread central and autonomic neurotransmitter" [MeSH:National Library of Medicine_Medical Subject Headings, pvb:Pierre Vanden Borre_Mouse Genome Informatics Curator]
synonym: "abnormal circulating norepinephrine level" EXACT []
is_a: MT:0003964 ! noradrenaline level
is_a: MT:0005418 ! circulating hormone level

[Term]
id: MT:0005666
name: adipose tissue physiology
namespace: Trait.ontology
subset: slim_cattle
subset: slim_pig
is_a: MT:0005375 ! adipose tissue trait

[Term]
id: MT:0005667
name: circulating leptin level
namespace: Trait.ontology
def: "aberrant blood concentration of the peptide hormone secreted by white adipocytes and believed to regulate food intake and energy balance" [J:34751, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0005418 ! circulating hormone level

[Term]
id: MT:0005670
name: white fat physiology
namespace: Trait.ontology
is_a: MT:0005666 ! adipose tissue physiology

[Term]
id: MT:0005671
name: response to transplant
namespace: Trait.ontology
def: "the body's reaction to the grafting of organs, tissues, or cells taken from the same individual for another area of the body or from another individual" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:52834, MeSH:National Library of Medicine_Medical Subject Headings]
is_a: MT:0001790 ! immune system physiology

[Term]
id: MT:0005673
name: susceptibility to graft versus host disease
namespace: Trait.ontology
def: "less likelihood of developing clinical symptoms of anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the a graft versus host reaction, which is an immunological attack mounted by a graft against the host because of tissue incompatibility when immunologically competent cells are transplanted to an immunologically incompetent host" [cwg:Carroll-Ann W. Goldsmith_Mouse Genome Informatics Curator, J:52834, MeSH:National Library of Medicine_Medical Subject Headings]
synonym: "decreased susceptibility to graft vs host disease" EXACT []
synonym: "decreased susceptibility to GVHD" EXACT []
is_a: MT:0005671 ! response to transplant

[Term]
id: MT:0005674
name: arterial trunk division completeness
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the extent of septation of the path through which blood exits the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0000135 ! outflow tract morphology

[Term]
id: MT:0005675
name: gall bladder size
namespace: Trait.ontology
def: "reduced size of the gall bladder, the organ that serves as a storage reservoir for bile" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:25724]
is_a: MT:0005084 ! gall bladder morphology

[Term]
id: MT:0006000
name: corneal epithelium morphology
namespace: Trait.ontology
def: "malformation in the one or more of the layers of epithelial cells covering the front of the cornea" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001312 ! cornea morphology

[Term]
id: MT:0006001
name: intestinal transit time
namespace: Trait.ontology
def: "increase or decrease in the time it takes for a bolus of material to pass through the intestine" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001664 ! digestion

[Term]
id: MT:0006002
name: small intestinal transit time
namespace: Trait.ontology
def: "increase or decrease in the time it takes for a bolus of material to pass through the small intestine" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006001 ! intestinal transit time

[Term]
id: MT:0006003
name: large intestinal transit time
namespace: Trait.ontology
def: "increase or decrease in the time it takes for a bolus of material to pass through the large intestine" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006001 ! intestinal transit time

[Term]
id: MT:0006004
name: interneuron morphology
namespace: Trait.ontology
def: "malformation or absence of neurons that exclusively interact with other neurons" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002882 ! neuron

[Term]
id: MT:0006005
name: interneuron number
namespace: Trait.ontology
def: "fewer than normal number of neurons that interact only with other neurons" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006004 ! interneuron morphology

[Term]
id: MT:0006006
name: sensory neuron number
namespace: Trait.ontology
def: "greater than normal numbers of cells that innervate an effector (muscle or glandular) tissue" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000965 ! sensory neuron morphology

[Term]
id: MT:0006007
name: basal ganglion morphology
namespace: Trait.ontology
def: "malformation or absence of any of a group of nuclei associated with the ability to carry out willed movements, including the caudate, putamen, nucleus accumbens, globus pallidus, substantia nigra, and subthalamic nucleus" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal basal ganglia morphology" EXACT []
is_a: MT:0000783 ! forebrain morphology

[Term]
id: MT:0006008
name: neurogenesis
namespace: Trait.ontology
def: "impaired or altered growth or development of neurons" [smb:Susan M. Bello_Mouse Genome Informatics Curator, Taber's Cyclopedic Medical Dictionary_19th edition:ISBN N 0-8036-0655-99]
synonym: "abnormal neuronal proliferation" EXACT []
is_a: MT:0003861 ! nervous system development

[Term]
id: MT:0006009
name: neuronal migration
namespace: Trait.ontology
def: "defective or impaired movement of immature neurons from germinal zones to specific positions where they will reside as they mature" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006008 ! neurogenesis

[Term]
id: MT:0006011
name: endolymphatic duct morphology
namespace: Trait.ontology
def: "form or structure of the small membranous canal, connecting with both saccule and utricle of the membranous labyrinth, passing through the aqueduct of vestibule, and terminating in the endolymphatic sac." [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal ductus endolymphaticus" EXACT []
is_a: MT:0000026 ! inner ear morphology

[Term]
id: MT:0006014
name: endolymphatic sac size
namespace: Trait.ontology
def: "diameter or volume of the endolymphatic sac" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:67072, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006011 ! endolymphatic duct morphology

[Term]
id: MT:0006018
name: tympanic membrane morphology
namespace: Trait.ontology
def: "form or structure of the thin, tense membrane forming the greater part of the lateral wall of the tympanic cavity and separating it from the external acoustic meatus; the tympanic membrane constitutes the boundary between the external and middle ear." [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:46639, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "drum membrane morphology" EXACT []
synonym: "membrana tympani morphology" EXACT []
synonym: "myringa morphology" EXACT []
synonym: "myrinx morphology" EXACT []
is_a: MT:0000049 ! middle ear morphology

[Term]
id: MT:0006019
name: tympanic membrane size
namespace: Trait.ontology
def: "area of the drum membrane that forms the greater part of the lateral wall of the tympanic cavity" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006018 ! tympanic membrane morphology

[Term]
id: MT:0006020
name: tympanic ring size
namespace: Trait.ontology
def: "diameter or area of the tympanic ring" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000030 ! tympanic ring morphology

[Term]
id: MT:0006021
name: Reissner membrane morphology
namespace: Trait.ontology
def: "form or structure of Reissner's membrane which separates the cochlear duct from the vestibular canal, i.e. the endolymph of the scala media from the perilymph of the scala vestibuli; the Reissner membrane consists of squamous epithelial cells with microvilli toward the ductus, a basement membrane, and a thin layer of connective tissue toward the scala. " [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "membrana vestibularis ductus cochlearis morphology" EXACT []
synonym: "morphology of the vestibular wall of cochlear duct" EXACT []
synonym: "paries vestibularis ductus cochlearis morphology" EXACT []
synonym: "Reissner's membrane morphology" EXACT []
synonym: "vestibular membrane morphology" EXACT []
is_a: MT:0000031 ! cochlea morphology

[Term]
id: MT:0006023
name: Reissner membrane integrity
namespace: Trait.ontology
def: "susceptibility of the membrane to loss of attachment or collapse" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "Reissner's membrane integrity" EXACT []
is_a: MT:0006021 ! Reissner membrane morphology

[Term]
id: MT:0006025
name: Reissner membrane size
namespace: Trait.ontology
def: "an increase in the volume of endolymphatic fluid that results in distortion of the vestibular membrane" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "distended Reissner's membrane" EXACT []
is_a: MT:0006021 ! Reissner membrane morphology

[Term]
id: MT:0006026
name: terminal bronchiole tube size
namespace: Trait.ontology
def: "increased volume of the terminal lung buds" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:85546, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "dilated terminal lung buds" EXACT []
is_a: MT:0002268 ! terminal bronchiole morphology

[Term]
id: MT:0006027
name: respiratory alveologenesis
namespace: Trait.ontology
def: "a block or reduction in the generation of alveoli" [J:85546, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "reduced alveolar formation" EXACT []
synonym: "reduced alveolarization" EXACT []
is_a: MT:0001176 ! lung development

[Term]
id: MT:0006028
name: bronchiole branching
namespace: Trait.ontology
def: "a block or reduction in the morphogenesis of the bronchioles" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "reduced bronchiole branching" EXACT []
is_a: MT:0001176 ! lung development

[Term]
id: MT:0006029
name: sclerotome
namespace: Trait.ontology
def: "malformation of the one or more of the masses of mesodermal tissue that is derived from the somites and is adjacent to the notochord that give rise to the ribs and vertebrae" [smb:Susan M. Bello_Mouse Genome Informatics Curator, Taber's Cyclopedic Medical Dictionary_19th edition:ISBN N 0-8036-0655-99]
is_a: MT:0002113 ! skeleton development

[Term]
id: MT:0006030
name: otic vesicle formation
namespace: Trait.ontology
def: "formation of the simple epithelial sac formed from the otic placode that gives rise to the structures of the inner ear" [J:57313, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "otocyst formation" EXACT []
is_a: MT:0003938 ! ear development

[Term]
id: MT:0006031
name: branchial pouch morphology
namespace: Trait.ontology
def: "malformation or anomaly in the series of grooves that form between the branchial arches; these endodermal evaginations develop into epithelial tissues and organs" [Gray's Anatomy:ISBN 0-914294-08-3, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal pharyngeal pouch morphology" EXACT []
is_a: MT:0002085 ! embryonic tissue morphology

[Term]
id: MT:0006032
name: ureteric bud morphology
namespace: Trait.ontology
def: "anomaly in the formation or development of the ureteric bud that with the metanephric mesenchyme gives rise to the kidneys " [J:57313, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000527 ! kidney development

[Term]
id: MT:0006033
name: external auditory canal morphology
namespace: Trait.ontology
def: "form or structure of the canal that connects the outer and middle ear" [J:57313, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "external meatus morphology" EXACT []
is_a: MT:0002177 ! outer ear morphology

[Term]
id: MT:0006034
name: urine myoglobin level
namespace: Trait.ontology
def: "presence of myoglobin in the urine" [RGD:Rat Genome Database submission, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "myoglobinuria" RELATED []
is_a: MT:0005160 ! urine protein level

[Term]
id: MT:0006035
name: mitochondrial morphology
namespace: Trait.ontology
def: "anomalous structure of the cellular organelles responsible for energy production" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000358 ! cell content/ morphology

[Term]
id: MT:0006036
name: mitochondrial physiology
namespace: Trait.ontology
def: "anomalous function of of the cellular organelles responsible for energy production" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005621 ! cell physiology

[Term]
id: MT:0006037
name: mitochondrial proliferation
namespace: Trait.ontology
def: "anomalous reproduction of the cellular organelles responsible for energy production" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006036 ! mitochondrial physiology

[Term]
id: MT:0006049
name: semilunar valve integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the valves that gate the flow of blood from the ventricles into the aorta and pulmonary trunk" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0000053 ! heart integrity
relationship: part_of MT:0002746 ! semilunar valve morphology

[Term]
id: MT:0006050
name: pulmonary fibrosis
namespace: Trait.ontology
def: "formation of fibrous tissue within the lung often resulting from inflammation or injury " [RGD:Rat Genome Database submission, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "lung fibrosis" EXACT []
is_a: MT:0001175 ! lung morphology

[Term]
id: MT:0006051
name: brainstem hemorrhage
namespace: Trait.ontology
def: "bleeding into the brain stem" [RGD:Rat Genome Database submission, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "brain stem bleeding" EXACT []
synonym: "brain stem hemorrhage" EXACT []
is_a: MT:0001915 ! intracranial hemorrhage

[Term]
id: MT:0006052
name: cerebellum hemorrhage
namespace: Trait.ontology
def: "bleeding into the cerebellum" [RGD:Rat Genome Database submission, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "cerebellum bleeding" EXACT []
is_a: MT:0001915 ! intracranial hemorrhage

[Term]
id: MT:0006053
name: hypothalamus hemorrhage
namespace: Trait.ontology
def: "bleeding into the hypothalamus" [RGD:Rat Genome Database submission, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "hypothalamic bleeding" EXACT []
is_a: MT:0001915 ! intracranial hemorrhage

[Term]
id: MT:0006054
name: spinal hemorrhage
namespace: Trait.ontology
def: "bleeding into the spine" [RGD:Rat Genome Database submission, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "spinal bleeding" EXACT []
synonym: "spinal cord hemorrhage" EXACT []
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0006055
name: blood vessel endothelial cell morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the cells that line the blood vessels" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "vascular endothelial cell morphology" RELATED []
synonym: "vascular endothelium morphology" EXACT []
xref: MP:0006005
relationship: part_of MT:0001614 ! blood vessel morphology

[Term]
id: MT:0006057
name: blood vessel endothelial cell number
namespace: Trait.ontology
def: "count of the cells that line blood vessels" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "vascular endothelial cell number" RELATED []
relationship: part_of MT:0006055 ! blood vessel endothelial cell morphology

[Term]
id: MT:0006058
name: cerebral infarction size
namespace: Trait.ontology
def: "decreased size of necrotic area of the cerebrum resulting from a sudden insufficiency of arterial or venous blood supply " [RGD:Rat Genome Database submission, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003075 ! response to CNS ischemic injury

[Term]
id: MT:0006061
name: atrium symmetry
namespace: Trait.ontology
def: "the degree to which the sturcture of the right and left atria reflect each other" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "atrial symmetry" RELATED []
relationship: part_of MT:0000508 ! right-sided isomerism
relationship: part_of MT:0003105 ! heart atrium morphology

[Term]
id: MT:0006062
name: vena cava morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of either of the two largest veins in the body" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "caval vein morphology" EXACT []
xref: MP:0006062
is_a: MT:0002725 ! vein morphology

[Term]
id: MT:0006063
name: inferior vena cava morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the principal vein draining blood from the lower portion of the body" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "abnormal inferior caval vein" EXACT []
is_a: MT:0006062 ! vena cava morphology

[Term]
id: MT:0006064
name: superior vena cava morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the principal vein draining blood from the upper portion of the body" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "abnormal superior caval vein" EXACT []
is_a: MT:0006062 ! vena cava morphology

[Term]
id: MT:0006065
name: heart position
namespace: Trait.ontology
def: "the location or orientation of the heart within the chest cavity" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "cardiac position" RELATED []
relationship: part_of MT:0000266 ! cardiac morphology

[Term]
id: MT:0006066
name: clearance of atrial thrombosis
namespace: Trait.ontology
def: "slower removal of a thrombus from the atria of the heart" [RGD:Rat Genome Database submission, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001855 ! atrial thrombosis

[Term]
id: MT:0006068
name: horizontal cell morphology
namespace: Trait.ontology
def: "anomalous structure of the laterally interconnecting neurons in the outer plexiform layer" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000965 ! sensory neuron morphology
is_a: MT:0001325 ! retina morphology

[Term]
id: MT:0006069
name: retinal neuronal layer morphology
namespace: Trait.ontology
def: "malformation in any of the neuronal layers that make up the retina, including the ganglion cell, inner plexiform, inner nuclear, outer plexiform, outer nuclear layers, the inner and outer segments" [Gray's Anatomy:ISBN 0-914294-08-3, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003727 ! retinal layer morphology

[Term]
id: MT:0006070
name: retinal photoreceptor number
namespace: Trait.ontology
def: "greater than the expected number of rods and/or cones" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001004 ! photoreceptor morphology

[Term]
id: MT:0006071
name: retinal progenitor morphology
namespace: Trait.ontology
def: "anomaly in the proliferation or differentiation of the cells that give rise to the various cells of the retina" [J:92622, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001286 ! eye development

[Term]
id: MT:0006072
name: retinal apoptosis
namespace: Trait.ontology
def: "increase or decrease in the number of cells in the retina undergoing programmed cell death" [J:92622, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001325 ! retina morphology

[Term]
id: MT:0006073
name: retinal bipolar cell morphology
namespace: Trait.ontology
def: "anomalous structure of the cells that transmit signals from the photoreceptors to retinal amacrine and ganglion cells" [J:92623, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001325 ! retina morphology

[Term]
id: MT:0006074
name: retinal rod bipolar cell morphology
namespace: Trait.ontology
def: "anomalous structure of the bipolar cells that function in low light and transmit signals only through amacrine cells" [J:92623, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006073 ! retinal bipolar cell morphology

[Term]
id: MT:0006075
name: retinal cone bipolar cell morphology
namespace: Trait.ontology
def: "anomalous structure of the retinal bipolar cells that connect to both ganglion and amacrine cells" [J:92623, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006073 ! retinal bipolar cell morphology

[Term]
id: MT:0006076
name: circulating homocysteine level
namespace: Trait.ontology
def: "aberrant concentration in the blood of this amino acid" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal blood serum homocysteine level" EXACT []
is_a: MT:0005311 ! circulating amino acid level

[Term]
id: MT:0006077
name: inguinal hernia
namespace: Trait.ontology
def: "hernia through the abdominal wall in the region of the groin known as Hesselbach's triangle" [J:74295, smb:Susan M. Bello_Mouse Genome Informatics Curator, Taber's Cyclopedic Medical Dictionary_19th edition:ISBN N 0-8036-0655-99]
is_a: MT:0000757 ! herniated abdominal wall

[Term]
id: MT:0006078
name: nipple morphology
namespace: Trait.ontology
def: "malformation of the erectile protuberance at the tip of the mammary gland" [J:92627, smb:Susan M. Bello_Mouse Genome Informatics Curator, Taber's Cyclopedic Medical Dictionary_19th edition:ISBN N 0-8036-0655-99]
subset: slim_cattle
subset: slim_pig
synonym: "teat morphology" EXACT []
is_a: MT:0000627 ! mammary gland morphology

[Term]
id: MT:0006079
name: stomach tumor
namespace: Trait.ontology
def: "presence of abnormal rapidly proliferating cells in the stomach, usually in the form of a distinct mass" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "gastric tumor" EXACT []
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0006080
name: CNS ischemia
namespace: Trait.ontology
def: "abnormal incidence of or response to loss of circulation in a region of the brain; may be induced or spontaneous" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "CNS stroke" EXACT []
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0006081
name: spontaneous CNS ischemia
namespace: Trait.ontology
def: "greater than normal occurrence of loss of circulation in a region of the brain" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "increased CNS stroke" EXACT []
is_a: MT:0006080 ! CNS ischemia

[Term]
id: MT:0006082
name: CNS inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the brain and/or spinal cord" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "encephalomyelitis" EXACT []
is_a: MT:0001846 ! tissue specific inflammatory response
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0006083
name: blood vessel elastic tissue morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the tissue that is found in the tunica media of the vessels wall and allows vessels to stretch" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "elastic laminae morphology" EXACT []
synonym: "vascular elastic tissue morphology" RELATED []
relationship: part_of MT:0001614 ! blood vessel morphology

[Term]
id: MT:0006084
name: circulating phospholipid level
namespace: Trait.ontology
def: "anomalous concentration in the blood of the fat derivatives in which one fatty acid has been replaced by a phosphate group" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003949 ! circulating lipid level

[Term]
id: MT:0006087
name: body mass index
namespace: Trait.ontology
def: "greater than normal average of a measure of weight for height" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
subset: slim_pig
synonym: "increased BMI" EXACT []
is_a: MT:0001259 ! body weight

[Term]
id: MT:0006088
name: blood-cerebrospinal fluid barrier integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness  group of barriers and transport systems in the choroid plexus located in the lateral, third, and fourth brain ventricles that controls the entrance of substances into the cerebrospinal fluid from the blood" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
comment: this should only be in morphology
synonym: "abnormal blood-CSF barrier" EXACT []
relationship: part_of MT:0000085 ! blood-cerebrospinal fluid barrier morphology

[Term]
id: MT:0006089
name: saccule morphology
namespace: Trait.ontology
def: "structure or form of the smaller of the two sacs in the vestibule" [J:92940, smb:Susan M. Bello_Mouse Genome Informatics Curator, Taber's Cyclopedic Medical Dictionary_19th edition:ISBN N 0-8036-0655-99]
is_a: MT:0004425 ! otolith organ morphology

[Term]
id: MT:0006090
name: utricle morphology
namespace: Trait.ontology
def: "structure or form of the larger of the two sacs in the vestibule" [J:92940, smb:Susan M. Bello_Mouse Genome Informatics Curator, Taber's Cyclopedic Medical Dictionary_19th edition:ISBN N 0-8036-0655-99]
is_a: MT:0004425 ! otolith organ morphology

[Term]
id: MT:0006091
name: olfactory epithelium morphology
namespace: Trait.ontology
def: "malformation in the epithelial cells that line the interior of the nose" [J:92950, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005499 ! olfactory system morphology

[Term]
id: MT:0006092
name: olfactory neuron morphology
namespace: Trait.ontology
def: "malformation in the neurons that are activated by specific odorants" [J:92950, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000965 ! sensory neuron morphology

[Term]
id: MT:0006093
name: artery vein separation
namespace: Trait.ontology
def: "non-fusion of an artery and vein" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_obsolete: true

[Term]
id: MT:0006096
name: retinal bipolar cell number
namespace: Trait.ontology
def: "count of the cells that transmit signals from the photoreceptors to retinal amacrine and ganglion cells" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:65410, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006073 ! retinal bipolar cell morphology

[Term]
id: MT:0006097
name: cerebellar lobule formation
namespace: Trait.ontology
def: "anomaly in the formation of the lobes of the cerebellum" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:65410, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000854 ! cerebellum development

[Term]
id: MT:0006099
name: granule layer thickness
namespace: Trait.ontology
def: "reduced thickness of the innermost cortical layer of the cerebellum that contains granule cells" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:65410, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "thin internal granule layer" EXACT []
is_a: MT:0000886 ! cerebellar granule layer morphology

[Term]
id: MT:0006100
name: tegmentum morphology
namespace: Trait.ontology
def: "any structural alterations or malfunction of the floor of the midbrain which extends from the substantia nigra to the level of the cerebral aqueduct." [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal mesencephalic tegmentum" EXACT []
is_a: MT:0000897 ! midbrain morphology

[Term]
id: MT:0006102
name: tegmentum size
namespace: Trait.ontology
def: "reduced size of the floor of the midbrain which extends from the substantia nigra to the level of the cerebral aqueduct" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "thin tegmentum" EXACT []
is_a: MT:0006100 ! tegmentum morphology

[Term]
id: MT:0006103
name: midbrain roof plate morphology
namespace: Trait.ontology
def: "any structural alterations or malfunction of the mesencephalic roof plate, including the caudal and rostral part of the midbrain roof" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000897 ! midbrain morphology

[Term]
id: MT:0006104
name: tectum morphology
namespace: Trait.ontology
def: "any structural alterations or malfunction of the rostral part of the midbrain roof" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:65762, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006103 ! midbrain roof plate morphology

[Term]
id: MT:0006105
name: tectum size
namespace: Trait.ontology
def: "reduced size of the rostral part of the midbrain roof" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:65410, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "thin tectum" EXACT []
is_a: MT:0006104 ! tectum morphology

[Term]
id: MT:0006107
name: atrioventricular canal morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the common canal connecting the primordial atrium and ventricle" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
relationship: part_of MT:0000267 ! heart development

[Term]
id: MT:0006108
name: hindbrain development
namespace: Trait.ontology
def: "anomaly in the formation or pattering of the caudal region of the brain" [J:93573, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000913 ! brain development

[Term]
id: MT:0006109
name: fibrillation
namespace: Trait.ontology
def: "contraction or quivering of individual cardiac muscle fibers" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0001636 ! heartbeat regularity

[Term]
id: MT:0006110
name: ventricular fibrillation
namespace: Trait.ontology
def: "contraction or quivering of individual cardiac muscle fibers in the ventricles" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0006109 ! fibrillation

[Term]
id: MT:0006111
name: coronary circulation
namespace: Trait.ontology
def: "flow of blood through the vessels that supply the heart" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0002128 ! blood circulation

[Term]
id: MT:0006113
name: heart septum morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the wall between the atria or ventricles of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "cardiac septum morphology" EXACT []
synonym: "heart septal morphology" EXACT []
relationship: part_of MT:0000266 ! cardiac morphology

[Term]
id: MT:0006114
name: cardiac sounds
namespace: Trait.ontology
def: "heart sounds resulting from blood flow through the valves or outflow tract" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0002128 ! blood circulation

[Term]
id: MT:0006117
name: aortic valve patency
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the openness of the valve between the left ventricle and the ascending aorta" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
relationship: part_of MT:0002747 ! aortic valve integrity

[Term]
id: MT:0006122
name: mitral valve patency
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the openness of the valve between the left atrium and left ventricle of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
relationship: part_of MT:0000286 ! mitral valve integrity

[Term]
id: MT:0006124
name: tricuspid valve patency
namespace: Trait.ontology
def: "openness of the valve between the right atrium and the right ventricle of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
relationship: part_of MT:0002624 ! tricuspid valve integrity

[Term]
id: MT:0006126
name: outflow tract development
namespace: Trait.ontology
def: "any measurable or observable characteristics pertaining to the process by which the outflow tract transforms from a simple sphincter into its mature form" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0000267 ! heart development

[Term]
id: MT:0006127
name: great vessel configuration
namespace: Trait.ontology
def: "any measurable characteristic of the arrangement of the pulmonary vessels and aorta in relation to the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0000135 ! outflow tract morphology

[Term]
id: MT:0006128
name: pulmonary valve patency
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the openness of the valve between the right ventricle and the pulmonary trunk" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
relationship: part_of MT:0002748 ! pulmonary valve integrity

[Term]
id: MT:0006133
name: artery composition
namespace: Trait.ontology
def: "any measurable or observable characteristic pertaining to the types and ratios of cells or substances within the blood vessels that carry blood away from the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "arterial composition" RELATED []
relationship: part_of MT:0002191 ! artery morphology

[Term]
id: MT:0006135
name: artery patency
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the openness of the blood vessels that carry blood away from the heart" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "arterial patency" RELATED []
is_a: MT:0005412 ! blood vessel patency
relationship: part_of MT:0003410 ! artery integrity

[Term]
id: MT:0006137
name: vein patency
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the openness of the blood vessels that carry blood towards the heart" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "venous patency" RELATED []
is_a: MT:0005412 ! blood vessel patency
relationship: part_of MT:0000118 ! vein integrity

[Term]
id: MT:0006138
name: cardiac function
namespace: Trait.ontology
def: "ability of the heart to adequately pump blood throughout the body" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0001544 ! cardiovascular system physiology

[Term]
id: MT:0006139
name: rhabdomyoma
namespace: Trait.ontology
def: "a benign neoplasm of striated muscle " [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0006140
name: cardiac rhabdomyoma
namespace: Trait.ontology
def: "the most common benign tumor of the myocardium it may be associated with tuberous sclerosis" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006139 ! rhabdomyoma

[Term]
id: MT:0006141
name: atrioventricular node conduction
namespace: Trait.ontology
def: "generation or transfer of cardiac electrical impulses from the atrioventricular node to the atrioventricular bundle" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0003137 ! impulse conducting system function

[Term]
id: MT:0006142
name: sinoatrial node conduction
namespace: Trait.ontology
def: "the generation or transfer of electrical impulses that trigger contraction of the atria and ventricles" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "sinus node conduction" EXACT []
is_a: MT:0003137 ! impulse conducting system function

[Term]
id: MT:0006145
name: legal blindness (sensu H. sapiens)
namespace: Trait.ontology
def: "the best corrected visual acuity is 20/200, or the visual field is 20 degrees or less" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002001 ! blindness

[Term]
id: MT:0006146
name: night blindness
namespace: Trait.ontology
def: "poor vision at night or in dim light" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002001 ! blindness

[Term]
id: MT:0006147
name: monocular blindness
namespace: Trait.ontology
def: "loss of vision in only one eye, may be transient" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002001 ! blindness

[Term]
id: MT:0006148
name: binocular blindness
namespace: Trait.ontology
def: "loss of vision in both eyes, may be transient" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002001 ! blindness

[Term]
id: MT:0006149
name: blurred vision
namespace: Trait.ontology
def: "loss of visual acuity or ability to distinguish small details" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002090 ! vision

[Term]
id: MT:0006150
name: double vision
namespace: Trait.ontology
def: "two images are perceived when only a single object is present" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "diplopia" EXACT []
is_a: MT:0002090 ! vision

[Term]
id: MT:0006151
name: astigmatism
namespace: Trait.ontology
def: "the cornea is asymmetrically curved, causing out-of-focus vision" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001312 ! cornea morphology

[Term]
id: MT:0006152
name: tunnel vision
namespace: Trait.ontology
def: "loss of peripheral vision" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002090 ! vision

[Term]
id: MT:0006153
name: hypermetropia
namespace: Trait.ontology
def: "light entering the eye focuses behind the retina, instead of directly on it" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "farsighted" EXACT []
synonym: "hyperopia" EXACT []
is_a: MT:0002090 ! vision

[Term]
id: MT:0006154
name: eye movement relative to the midline
namespace: Trait.ontology
is_a: MT:0001389 ! eye movements

[Term]
id: MT:0006156
name: visual pursuit
namespace: Trait.ontology
is_a: MT:0001389 ! eye movements

[Term]
id: MT:0006158
name: vertical supranuclear eye movement
namespace: Trait.ontology
is_a: MT:0001389 ! eye movements

[Term]
id: MT:0006159
name: ocular albinism
namespace: Trait.ontology
def: "absence of melanin production in the eye only" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005172 ! lack of eye pigmentation

[Term]
id: MT:0006160
name: heterochromatic iridis
namespace: Trait.ontology
def: "a difference in color between the irises of the two eyes or between parts of one iris" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005102 ! iris pigmentation

[Term]
id: MT:0006162
name: eyelid thickness
namespace: Trait.ontology
def: "increased width of the eyelid" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001340 ! eyelid morphology

[Term]
id: MT:0006163
name: ankyloblepharon filiform
namespace: Trait.ontology
def: "abnormal connection of the upper and lower eyelids formed by fibrous tissue" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001340 ! eyelid morphology

[Term]
id: MT:0006164
name: ectropion
namespace: Trait.ontology
def: "abnormal eversion of the upper or lower eyelid that leaves the eye exposed and dry" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "rolled out eyelids" EXACT []
is_a: MT:0001340 ! eyelid morphology

[Term]
id: MT:0006165
name: entropion
namespace: Trait.ontology
def: "abnormal inward rolling of the eyelid, most commonly the lower lid" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "rolled in eyelids" EXACT []
is_a: MT:0001340 ! eyelid morphology

[Term]
id: MT:0006166
name: width of eyelid opening
namespace: Trait.ontology
def: "eyelids open abnormally wide" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003671 ! eyelid opening

[Term]
id: MT:0006167
name: eyelid edema
namespace: Trait.ontology
def: "an abnormal accumulation of fluid in the eyelid" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001340 ! eyelid morphology
is_a: MT:0001785 ! edema

[Term]
id: MT:0006168
name: epicanthus inversus
namespace: Trait.ontology
def: "a vertical fold of skin runs from the lower eyelid up either side of the nose" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001340 ! eyelid morphology

[Term]
id: MT:0006169
name: eyelid tumor
namespace: Trait.ontology
def: "presence of abnormal rapidly proliferating cells in the eyelid, usually in the form of a distinct mass" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "tumor of the eyelid" EXACT []
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0006170
name: eyelid myxoma
namespace: Trait.ontology
def: "a benign tumor composed of connective tissue embedded in mucus found in the eyelid" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003391 ! myxoma
is_a: MT:0006169 ! eyelid tumor

[Term]
id: MT:0006171
name: eyelid neuroma
namespace: Trait.ontology
def: "a tumor composed of nerve tissue found in the eyelid" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006169 ! eyelid tumor

[Term]
id: MT:0006172
name: eyelid lipodermoid
namespace: Trait.ontology
def: "a congenital, yellowish-white, fatty, benign tumor located beneath the conjunctiva of the eye" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006169 ! eyelid tumor

[Term]
id: MT:0006173
name: myeloid dendritic cell morphology
namespace: Trait.ontology
def: "anomaly in the formation or structure of phagocytic dendritic cells principally found in the epidermis and mucosal epithelium" [J:95147, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal Langerhans cell morphology/development" EXACT []
is_a: MT:0001601 ! myelopoiesis
is_a: MT:0005461 ! dendritic cell morphology/development

[Term]
id: MT:0006174
name: isthmic organizer morphology
namespace: Trait.ontology
def: "malformation in the organizing signaling center that forms at the boundary between the midbrain and hindbrain and plays essential role in development of the midbrain and anterior hindbrain" [J:71074, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000913 ! brain development

[Term]
id: MT:0006175
name: choroid size
namespace: Trait.ontology
def: "wasting of the choroid" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005098 ! choroid morphology

[Term]
id: MT:0006176
name: choroid integrity
namespace: Trait.ontology
def: "a retrogressive impairment of function or destruction of the choroid" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "choroid dystrophy" EXACT []
is_a: MT:0005098 ! choroid morphology

[Term]
id: MT:0006177
name: choroid sclerosis
namespace: Trait.ontology
def: "thickening or hardening of the choroid usually secondary to atrophy" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005098 ! choroid morphology

[Term]
id: MT:0006178
name: eye tumor
namespace: Trait.ontology
def: "presence of abnormal rapidly proliferating cells in the eye, usually in the form of a distinct mass" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0006179
name: choroid tumor
namespace: Trait.ontology
def: "presence of abnormal rapidly proliferating cells in the choroid, usually in the form of a distinct mass" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006178 ! eye tumor

[Term]
id: MT:0006180
name: choroid hemangioma
namespace: Trait.ontology
def: "a benign tumor of the choroid, originating from the overgrowth of blood vessels" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002947 ! hemangioma
is_a: MT:0006179 ! choroid tumor

[Term]
id: MT:0006181
name: retina tumor
namespace: Trait.ontology
def: "presence of abnormal rapidly proliferating cells in the retina, usually in the form of a distinct mass" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006178 ! eye tumor

[Term]
id: MT:0006182
name: retinal hemangioma
namespace: Trait.ontology
def: "a benign tumor of the retina, originating from the overgrowth of blood vessels" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "retinal angioma" EXACT []
is_a: MT:0002947 ! hemangioma
is_a: MT:0006181 ! retina tumor

[Term]
id: MT:0006183
name: retinal hamartoma
namespace: Trait.ontology
def: "tumor-like focal abnormalities of the retina; rarely neoplastic" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006181 ! retina tumor

[Term]
id: MT:0006184
name: retinal astrocytoma
namespace: Trait.ontology
def: "a malignant tumor of nervous tissue composed of well-differentiated astrocytes located in the retina" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006181 ! retina tumor

[Term]
id: MT:0006185
name: retinal hemorrhage
namespace: Trait.ontology
def: "bleeding into the retina" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001325 ! retina morphology

[Term]
id: MT:0006186
name: retinal fibrosis
namespace: Trait.ontology
def: "invasion of fibrous connective tissue into the retina, often resulting from inflammation or injury" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001325 ! retina morphology

[Term]
id: MT:0006187
name: retinal deposits
namespace: Trait.ontology
def: "abnormal accumulation of material on the retina" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001325 ! retina morphology

[Term]
id: MT:0006188
name: retinal calcification
namespace: Trait.ontology
def: "pathologic deposition of calcium salts in the retina" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006187 ! retinal deposits
is_a: MT:0006209 ! intraocular calcification

[Term]
id: MT:0006190
name: retinal ischemia
namespace: Trait.ontology
def: "abnormal incidence of or response to loss of circulation in the retina; may be induced or spontaneous" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005253 ! eye physiology

[Term]
id: MT:0006191
name: conjunctival deposits
namespace: Trait.ontology
def: "abnormal accumulation of material on the conjunctiva" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001310 ! conjunctiva morphology

[Term]
id: MT:0006192
name: conjunctival blood vessel morphology
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the blood vessel network of the conjunctiva" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "conjunctival vascular morphology" RELATED []
synonym: "conjunctival vasculature" RELATED []
xref: MP:0006192
is_a: MT:0001310 ! conjunctiva morphology
is_a: MT:0001614 ! blood vessel morphology

[Term]
id: MT:0006194
name: keratoconjunctivitis
namespace: Trait.ontology
def: "inflammation of the conjunctiva and cornea" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001852 ! conjunctivitis

[Term]
id: MT:0006195
name: position of eyes in the eye socket
namespace: Trait.ontology
def: "eyes located further back in the eye socket than normal" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001299 ! eye distance/ position

[Term]
id: MT:0006196
name: ocular proptosis
namespace: Trait.ontology
def: "abnormal protrusion of the eyeball" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001299 ! eye distance/ position

[Term]
id: MT:0006198
name: enophthalmos
namespace: Trait.ontology
def: "sinking or retraction of the eye back into the socket" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "sunken eyes" EXACT []
is_a: MT:0006195 ! position of eyes in the eye socket

[Term]
id: MT:0006199
name: hypertropia
namespace: Trait.ontology
def: "vertical misalignment between the eyes " [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001299 ! eye distance/ position

[Term]
id: MT:0006200
name: vitreous body deposition
namespace: Trait.ontology
def: "abnormal accumulation of material in the vitreous body" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002699 ! vitreous body

[Term]
id: MT:0006201
name: vitreous body inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins, and leukocytes in the vitreous body" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001851 ! eye inflammation
is_a: MT:0002699 ! vitreous body

[Term]
id: MT:0006202
name: vitreous body hemorrhage
namespace: Trait.ontology
def: "bleeding into the vitreous body" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002699 ! vitreous body

[Term]
id: MT:0006209
name: intraocular calcification
namespace: Trait.ontology
def: "pathologic deposition of calcium salts in the eye" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002092 ! eye morphology

[Term]
id: MT:0006210
name: orbit size
namespace: Trait.ontology
def: "deviation from the normal size of the orbit" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005246 ! orbit morphology

[Term]
id: MT:0006212
name: orbit width
namespace: Trait.ontology
def: "increased size of the orbits" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006210 ! orbit size

[Term]
id: MT:0006213
name: orbit depth
namespace: Trait.ontology
def: "decrease in the depth of the orbit" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006210 ! orbit size

[Term]
id: MT:0006214
name: asymmetrical orbits
namespace: Trait.ontology
def: "loss of bilateral symmetry in the orbits" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005246 ! orbit morphology

[Term]
id: MT:0006215
name: optic disc morphology
namespace: Trait.ontology
alt_id: MT:0002793
def: "malformation of the area in the retina where all of the axons of the ganglion cells exit the retina to form the optic nerve" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001330 ! optic nerve morphology
is_a: MT:0002864 ! ocular fundus morphology

[Term]
id: MT:0006216
name: optic disc size
namespace: Trait.ontology
def: "deviation from the normal size of the optic disc" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006215 ! optic disc morphology

[Term]
id: MT:0006219
name: optic nerve integrity
namespace: Trait.ontology
def: "retrogressive pathologic change of the optic nerve" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001330 ! optic nerve morphology

[Term]
id: MT:0006220
name: optic nerve compression
namespace: Trait.ontology
def: "constriction of the optic nerve" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001330 ! optic nerve morphology

[Term]
id: MT:0006221
name: optic nerve fiber number
namespace: Trait.ontology
def: "less than the normal number of fibers in the optic nerve" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001330 ! optic nerve morphology

[Term]
id: MT:0006222
name: optic neuropathy
namespace: Trait.ontology
def: "damage of the optic nerve due to a blockage of its blood supply, to nutritional deficiencies, or to toxins" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001330 ! optic nerve morphology

[Term]
id: MT:0006223
name: optic nerve swelling
namespace: Trait.ontology
def: "accumulation of an excessive amount of fluid in the optic nerve; usually associated with an increase in intraocular pressure" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "papilledema" EXACT []
synonym: "pseudopapilledema" EXACT []
is_a: MT:0001330 ! optic nerve morphology
is_a: MT:0001785 ! edema

[Term]
id: MT:0006224
name: control of horizontal eye movement
namespace: Trait.ontology
is_a: MT:0001389 ! eye movements

[Term]
id: MT:0006225
name: ocular rupture
namespace: Trait.ontology
def: "tearing of the tissues of the eye" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002092 ! eye morphology

[Term]
id: MT:0006226
name: iris cell number
namespace: Trait.ontology
def: "less than the normal number of cells in the iris" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001322 ! iris morphology

[Term]
id: MT:0006227
name: iris development
namespace: Trait.ontology
def: "abnormal development or growth of the iris resulting in abnormal structure of the iris " [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001286 ! eye development
is_a: MT:0001322 ! iris morphology

[Term]
id: MT:0006228
name: iris size
namespace: Trait.ontology
def: "wasting of the iris" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001322 ! iris morphology

[Term]
id: MT:0006229
name: iris inflammation
namespace: Trait.ontology
def: "local accumulation of fluid, plasma proteins and leukocytes in the iris" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001851 ! eye inflammation

[Term]
id: MT:0006230
name: iris stroma cell number
namespace: Trait.ontology
def: "less than the normal number of cells in the iris stroma" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005208 ! iris stroma morphology
is_a: MT:0006226 ! iris cell number

[Term]
id: MT:0006231
name: iris tumor
namespace: Trait.ontology
def: "presence of abnormal rapidly proliferating cells in the iris, usually in the form of a distinct mass" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006178 ! eye tumor

[Term]
id: MT:0006232
name: Lisch nodule
namespace: Trait.ontology
def: "a focal growth that resembles a neoplasm but results from faulty development in the iris and containing melanocytes" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "iris hamartoma" EXACT []
is_a: MT:0006231 ! iris tumor

[Term]
id: MT:0006233
name: corneal adhesion to iris
namespace: Trait.ontology
def: "abnormal connection of the iris and cornea" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "irido-corneal adhesion" EXACT []
is_a: MT:0001312 ! cornea morphology
is_a: MT:0004222 ! synechia

[Term]
id: MT:0006234
name: iridoschisis
namespace: Trait.ontology
def: "separation of the anterior iris stroma from the posterior stroma and muscle layers" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001322 ! iris morphology

[Term]
id: MT:0006235
name: polycoria
namespace: Trait.ontology
def: "two or more pupils in one iris each with sphincter muscle." [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001317 ! pupil morphology

[Term]
id: MT:0006237
name: choroid blood vessel morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the blood vessels of the choroid" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "choroid vascular morphology" RELATED []
synonym: "choroid vasculature" RELATED []
is_a: MT:0001614 ! blood vessel morphology
is_a: MT:0005098 ! choroid morphology

[Term]
id: MT:0006238
name: choriocapillaris integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the capillaries forming the inner vascular layer of the choroid of the eye" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
relationship: part_of MT:0000093 ! choroid blood vessel integrity

[Term]
id: MT:0006240
name: anisocoria
namespace: Trait.ontology
def: "unequal size of pupils" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001317 ! pupil morphology

[Term]
id: MT:0006241
name: placement of pupils
namespace: Trait.ontology
def: "abnormal location of the pupil so that it is not in the center of the iris" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "corectopia" EXACT []
is_a: MT:0001317 ! pupil morphology

[Term]
id: MT:0006242
name: white pupil
namespace: Trait.ontology
def: "reflective white mass within the eye that gives the appearance of white pupil" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "leukokoria" EXACT []
is_a: MT:0001317 ! pupil morphology

[Term]
id: MT:0006243
name: pupil dilation reaction to light
namespace: Trait.ontology
is_a: MT:0002638 ! pupillary reflex

[Term]
id: MT:0006244
name: involuntary contraction of eyelids
namespace: Trait.ontology
def: "spasmodic winking caused by the involuntary contraction of an eyelid muscle" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "blepharospasm" EXACT []
is_a: MT:0005253 ! eye physiology

[Term]
id: MT:0006245
name: dislocated lens
namespace: Trait.ontology
def: "the lens is moved out of position because some or all of the supporting ligaments have broken" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001303 ! lens morphology

[Term]
id: MT:0006246
name: tumor of uvea
namespace: Trait.ontology
def: "presence of abnormal rapidly proliferating cells in the uvea, usually in the form of a distinct mass" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006178 ! eye tumor

[Term]
id: MT:0006247
name: intraocular melanoma
namespace: Trait.ontology
def: "a dark-pigmented, usually malignant tumor arising from a melanocyte occurring in the eye" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006246 ! tumor of uvea

[Term]
id: MT:0006248
name: lagopthalmos
namespace: Trait.ontology
def: "inability to completely close the eye" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005253 ! eye physiology

[Term]
id: MT:0006249
name: phthisis bulbi
namespace: Trait.ontology
def: "small, shrunken, malformed eye usually occurs as the end result of eye disease" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002697 ! eye size

[Term]
id: MT:0006250
name: line of Schwalbe morphology
namespace: Trait.ontology
def: "malformation of the thickened peripheral margin of the vitreous membrane of the cornea" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal Schwalbe's ring" EXACT []
is_a: MT:0005203 ! trabecular meshwork morphology

[Term]
id: MT:0006251
name: ability to open eyelids
namespace: Trait.ontology
def: "impaired ability to open the eyelids without any gross defect in eyelid morphology" [ncbi:Matthew Mailman_NCBI request, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0005253 ! eye physiology

[Term]
id: MT:0006252
name: lateral rectus eye movement
namespace: Trait.ontology
is_a: MT:0001389 ! eye movements

[Term]
id: MT:0006253
name: clinodactyly
namespace: Trait.ontology
def: "abnormal lateral curvature of one or more digits towards or away from each other" [J:98519, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002110 ! digit morphology

[Term]
id: MT:0006254
name: thin cerebral cortex
namespace: Trait.ontology
def: "decreased depth of the mantle covering the surface of the cerebral hemispheres" [J:84683, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000788 ! cerebral cortex morphology

[Term]
id: MT:0006256
name: gustatory papillae morphology
namespace: Trait.ontology
def: "malformation, absence, or atypical size or shape of the papillae that contain taste buds, including the fungiform, foliate, and circumvallate papillae" [J:55127, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal taste papillae" EXACT []
is_a: MT:0000764 ! tongue epithelium morphology

[Term]
id: MT:0006257
name: fungiform papillae morphology
namespace: Trait.ontology
def: "malformation, absence, or atypical size or shape of the mushroom-shaped papillae, which have a single taste bud at the tip, located mostly on the dorsal anterior portion of the tongue" [J:55127, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0006256 ! gustatory papillae morphology

[Term]
id: MT:0006258
name: circumvallate papillae morphology
namespace: Trait.ontology
def: "malformation, absence, or atypical size or shape of the large papillae, which have multiple taste buds in the trough surrounding the papillae, located near the base and on the dorsal side of the tongue" [J:55127, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal vallate papillae" EXACT []
is_a: MT:0006256 ! gustatory papillae morphology

[Term]
id: MT:0006259
name: foliate papillae morphology
namespace: Trait.ontology
def: "malformation, absence, or atypical size or shape of the papillae located on the sides of the tongue" [smb:Susan M. Bello_Mouse Genome Informatics Curator, Taber's Cyclopedic Medical Dictionary_19th edition:ISBN N 0-8036-0655-99]
is_a: MT:0006256 ! gustatory papillae morphology

[Term]
id: MT:0006260
name: gustatory papillae taste bud morphology
namespace: Trait.ontology
def: "malformation, absence, or atypical size or shape of the taste buds located on the gustatory papillae, which includes the fungiform, foliate, and circumvallate papillae" [J:55127, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001002 ! taste bud morphology

[Term]
id: MT:0006261
name: annular pancreas
namespace: Trait.ontology
def: "an abnormal ring or collar of pancreatic tissue that encircles the duodenum" [J:69854, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001944 ! pancreas morphology

[Term]
id: MT:0006262
name: testis tumor
namespace: Trait.ontology
def: "presence of abnormal rapidly proliferating cells in the testis, usually in the form of a distinct mass" [J:60034, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0006263
name: diastolic blood pressure
namespace: Trait.ontology
def: "the pressure in the arteries between heart beats when the heart is relaxed" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0000230 ! blood pressure

[Term]
id: MT:0006264
name: systolic blood pressure
namespace: Trait.ontology
def: "pressure in the arteries as the heart contracts and pumps blood into the arteries" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0000230 ! blood pressure

[Term]
id: MT:0006267
name: intercalated disc integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the electron dense junctional complex, at the end to end contacts of cardiac muscle cells, that contains two types of membrane junctions i.e. gap junctions and desmosomes" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
relationship: part_of MT:0000278 ! heart muscle fiber integrity

[Term]
id: MT:0006268
name: heart muscle desmosome integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of one type of membrane junctions found within the intercalated discs that provide mechanical integrity and prevent separation of adjacent cells during contraction of cardiac tissue" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "cardiac desmosome integrity" RELATED []
relationship: part_of MT:0000278 ! heart muscle fiber integrity

[Term]
id: MT:0006269
name: mammary gland growth during pregnancy
namespace: Trait.ontology
def: "anomaly in the extensive and rapid branching of the mammary ducts, expansion of mammary epithelium in the stroma between the ducts with or without abnormalities in nipple maturation " [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0000628 ! mammary gland development

[Term]
id: MT:0006270
name: mammary gland growth during lactation
namespace: Trait.ontology
def: "anomaly in the final stage of mammary growth that occurs during the start of lactation" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0000628 ! mammary gland development

[Term]
id: MT:0006271
name: involution of the mammary gland
namespace: Trait.ontology
def: "anomaly in the process during which mammary glands suspend milk protein production, the mammary alveolar structures collapse and secretory epithelial cells are lost" [llw2:Linda Washburn_Mouse Genome Informatics Curator]
is_a: MT:0000628 ! mammary gland development

[Term]
id: MT:0006272
name: renal organic anion excretion
namespace: Trait.ontology
def: "anomaly in the ability of the kidneys to eliminate organic acids (represented by the prototypical substrate para-aminohippurate (PAH))" [J:108655, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal renal organic anion secretion" EXACT []
is_a: MT:0005555 ! kidney excretion

[Term]
id: MT:0006273
name: renal organic cation excretion
namespace: Trait.ontology
def: "anomaly in the ability of the kidneys to eliminate organic bases (represented by the prototypical substrate tetraethylammonium (TEA))" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal renal organic cation secretion" EXACT []
is_a: MT:0005555 ! kidney excretion

[Term]
id: MT:0006274
name: urine sodium level
namespace: Trait.ontology
def: "any change in the level of excretion of sodium in the urine" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0001757 ! urine chemistry

[Term]
id: MT:0006276
name: autonomic nervous system physiology
namespace: Trait.ontology
def: "anomaly in the function of the sensory and motor neurons that run between the central nervous system (especially the hypothalamus and medulla oblongata) and various internal organs (heart, lungs, endocrine and exocrine glands), responsible for controlling involuntary bodily functions" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, smb:Susan M. Bello_Mouse Genome Informatics Curator, Taber's Cyclopedic Medical Dictionary_19th edition:ISBN N 0-8036-0655-99]
is_a: MT:0003633 ! nervous system physiology

[Term]
id: MT:0006277
name: parasympathetic nervous system physiology
namespace: Trait.ontology
def: "anomaly in the function of the craniosacral portion of the autonomic nervous system" [anna:Anna V. Anagnostopoulos_Mouse Genome Informatics Curator, J:78031, Taber's Cyclopedic Medical Dictionary_19th edition:ISBN N 0-8036-0655-99]
is_a: MT:0006276 ! autonomic nervous system physiology

[Term]
id: MT:0006279
name: limb development
namespace: Trait.ontology
def: "anomaly in the formation of the limbs" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003937 ! limbs/digits/tail development

[Term]
id: MT:0006280
name: digit development
namespace: Trait.ontology
def: "anomaly in the formation of the digits" [J:70592, smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0000572 ! autopod morphology

[Term]
id: MT:0006281
name: tail development
namespace: Trait.ontology
def: "anomaly in the formation of the tail" [smb:Susan M. Bello_Mouse Genome Informatics Curator]
is_a: MT:0003937 ! limbs/digits/tail development

[Term]
id: MT:0006282
name: posterior horn morphology
namespace: Trait.ontology
def: "anomalous structure of the dorsal gray matter of the spinal cord" [J:77764, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "abnormal dorsal horn morphology" EXACT []
synonym: "abnormal posterior column morphology" EXACT []
synonym: "abnormal posterior cornu morphology" EXACT []
is_a: MT:0000955 ! spinal cord morphology

[Term]
id: MT:0006283
name: medulloblastoma
namespace: Trait.ontology
def: "a solid, cancerous tumor originating in the cerebellum of the brain and of primitive neuroectodermal origin " [rbabiuk:Randall Babiuk_Mouse Genome Informatics Curator, smb:Susan M. Bello_Mouse Genome Informatics Curator]
synonym: "primitive neuroendocrine tumor" EXACT []
is_a: MT:0002019 ! tumor incidence

[Term]
id: MT:0007000
name: heart apex orientation
namespace: Trait.ontology
def: "the angle of the top of the heart in relation the the rostral-caudal axis of the body" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "cardiac apex directionality" RELATED []
relationship: part_of MT:0006065 ! heart position

[Term]
id: MT:0007001
name: endocardial cushion morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the mounds of embryonic connective tissue that bulge into the embryonic atrioventricular canal; these mounds eventually fuse to form the valves between the right and left atrioventricular orifices" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0000267 ! heart development

[Term]
id: MT:0007002
name: endocardial cushion size
namespace: Trait.ontology
def: "the physical dimensions, proportions, magnitude, or extent of the mounds of embryonic connective tissue that bulge into the embryonic atrioventricular canal; these mounds fuse to form the valves between the right and left atrioventricular orifices" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0007001 ! endocardial cushion morphology

[Term]
id: MT:0007003
name: endocardial cushion thickness
namespace: Trait.ontology
def: "the breadth of the mounds of embryonic connective tissue that bulge into the embryonic atrioventricular canal; these mounds fuse to form the valves between the right and left atrioventricular orifices" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0007002 ! endocardial cushion size

[Term]
id: MT:0007004
name: heart tube looping integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the completeness or soundness of the process by which the embryonic heart tube bends to transform from a straight tube into the final folded configuration of the adult heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0000269 ! heart tube looping morphogenesis

[Term]
id: MT:0007005
name: atrioventricular canal completeness
namespace: Trait.ontology
def: "any measurable or observable characteristic pertaining to the wholeness of the common canal connecting the primordial atrium and ventricle" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0006107 ! atrioventricular canal morphology

[Term]
id: MT:0007007
name: atrioventricular canal configuration
namespace: Trait.ontology
def: "any measurable characteristic of the arrangement of the common canal connecting the primordial atrium and ventricle" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0006107 ! atrioventricular canal morphology

[Term]
id: MT:0007009
name: atrium septum configuration
namespace: Trait.ontology
def: "any measurable or observable characteristic of the arrangement of the wall separating the upper chambers of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "atrial septal configuration" RELATED []
relationship: part_of MT:0007081 ! atrium septum morphology

[Term]
id: MT:0007010
name: cardiomyocyte number
namespace: Trait.ontology
def: "count of muscle cells in the heart as a whole or in any substructure of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "heart muscle cell number" RELATED []
relationship: part_of MT:0000061 ! heart muscle fiber morphology

[Term]
id: MT:0007012
name: mitral valve configuration
namespace: Trait.ontology
def: "any measurable characteristic of the arrangement of the valve between the left atrium and the left ventricle of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0000033 ! mitral valve morphology

[Term]
id: MT:0007013
name: mitral valve completeness
namespace: Trait.ontology
def: "any measurable or observable characteristic pertaining to the wholeness of the valve between the left atrium and the left ventricle of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0000286 ! mitral valve integrity

[Term]
id: MT:0007014
name: tricuspid valve completeness
namespace: Trait.ontology
def: "any measurable or observable characteristic pertaining to the wholeness of the valve between the right atrium and the right ventricle of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0002624 ! tricuspid valve integrity

[Term]
id: MT:0007016
name: tricuspid valve configuration
namespace: Trait.ontology
def: "any measurable characteristic of the arrangement of the valve between the right atrium and the right ventricle of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0000036 ! tricuspid valve morphology

[Term]
id: MT:0007017
name: aortic valve completeness
namespace: Trait.ontology
def: "any measurable or observable characteristic pertaining to the wholeness of the valve between the left ventricle and the ascending aorta" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0002747 ! aortic valve integrity

[Term]
id: MT:0007019
name: aortic valve configuration
namespace: Trait.ontology
def: "any measurable or observable characteristic of the arrangement of the valve between the left ventricle and the ascending aorta" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0000040 ! aortic valve morphology

[Term]
id: MT:0007021
name: pulmonary valve completeness
namespace: Trait.ontology
def: "any measurable or observable characteristic pertaining to the wholeness of the valve between the right ventricle and the pulmonary trunk" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0002748 ! pulmonary valve integrity

[Term]
id: MT:0007022
name: pulmonary valve configuration
namespace: Trait.ontology
def: "any measurable or observable characteristic of the arrangement of the valve between the right ventricle and the pulmonary trunk" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0000044 ! pulmonary valve morphology

[Term]
id: MT:0007024
name: left atrium configuration
namespace: Trait.ontology
def: "any measurable characteristic of the arrangement of the left upper chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0000020 ! left atrium morphology

[Term]
id: MT:0007025
name: left atrium completeness
namespace: Trait.ontology
def: "any measurable or observable characteristic pertaining to the wholeness of the left upper chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "left atrial completeness" RELATED []
relationship: part_of MT:0003923 ! left atrium integrity

[Term]
id: MT:0007026
name: left atrium weight
namespace: Trait.ontology
def: "mass of the left upper chamber of the heart times gravity" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "left atrial weight" RELATED []
relationship: part_of MT:0000012 ! left atrium size

[Term]
id: MT:0007027
name: right atrium weight
namespace: Trait.ontology
def: "mass of the right upper chamber of the heart times gravity" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "right atrial weight" RELATED []
relationship: part_of MT:0000005 ! right atrium size

[Term]
id: MT:0007028
name: heart weight
namespace: Trait.ontology
def: "mass of the heart times gravity" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
subset: slim_chkn
subset: slim_pig
synonym: "cardiac weight" RELATED []
is_a: MT:0005406 ! heart size

[Term]
id: MT:0007029
name: heart dimensions
namespace: Trait.ontology
def: "any measurable characteristic of the spacial extent of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "cardiac dimensions" RELATED []
is_a: MT:0005406 ! heart size

[Term]
id: MT:0007030
name: left ventricle volume
namespace: Trait.ontology
alt_id: MT:0007092
def: "physical bulk of or total amount of space encompassed by the left lower chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "left ventricle mass" EXACT []
relationship: part_of MT:0002753 ! left ventricle size

[Term]
id: MT:0007031
name: left ventricle weight
namespace: Trait.ontology
def: "mass of the left lower chamber of the heart times gravity" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0002753 ! left ventricle size

[Term]
id: MT:0007032
name: right ventricle volume
namespace: Trait.ontology
alt_id: MT:0007093
def: "physical bulk of or total amount of space encompassed by the right lower chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "right ventricle mass" EXACT []
synonym: "right ventricular mass" RELATED []
synonym: "right ventricular volume" RELATED []
relationship: part_of MT:0002754 ! right ventricle size

[Term]
id: MT:0007033
name: right ventricle weight
namespace: Trait.ontology
def: "mass of the right lower chamber of the heart times gravity" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
subset: slim_chkn
synonym: "right ventricular weight" RELATED []
relationship: part_of MT:0002754 ! right ventricle size

[Term]
id: MT:0007035
name: pericardium integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the fibroserous membrane covering the heart and beginning of the great vessels" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
comment: By this I mean measures that determine if the structure has all of the required parts, if there are any extra parts, and if there are any holes or disease present. - smb
synonym: "pericardial integrity" RELATED []
relationship: part_of MT:0000053 ! heart integrity
relationship: part_of MT:0000288 ! pericardium morphology

[Term]
id: MT:0007036
name: pericardium configuration
namespace: Trait.ontology
def: "any measurable characteristic of the arrangement of the pericardium in relation to the heart and/or great vessels" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "pericardial configuration" RELATED []
relationship: part_of MT:0000288 ! pericardium morphology

[Term]
id: MT:0007037
name: endocardial cushion completeness
namespace: Trait.ontology
def: "any measurable or observable characteristic pertaining to the wholeness of the mounds of embryonic connective tissue that bulge into the embryonic atrioventricular canal; these mounds fuse to form the valves between the right and left atrioventricular orifices" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0000297 ! endocardial cushion integrity

[Term]
id: MT:0007038
name: endocardial configuration
namespace: Trait.ontology
def: "any measurable characteristic of the arrangement of the mounds of embryonic connective tissue that bulge into the embryonic atrioventricular canal; these mounds eventually fuse to form the valves between the right and left atrioventricular orifices" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0007001 ! endocardial cushion morphology

[Term]
id: MT:0007041
name: heart tube configuration
namespace: Trait.ontology
def: "any measurable characteristic of the arrangement of the early embryonic heart in relation to itself and the surrounding tissue" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0000125 ! heart tube morphology

[Term]
id: MT:0007042
name: heart tube completeness
namespace: Trait.ontology
is_obsolete: true

[Term]
id: MT:0007044
name: aorta integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the main trunk of the systemic arteries" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "aortic integrity" RELATED []
is_a: MT:0003410 ! artery integrity
relationship: part_of MT:0000272 ! aorta morphology

[Term]
id: MT:0007046
name: aorta completeness
namespace: Trait.ontology
def: "any measurable or observable characteristic pertaining to the wholeness  of the main trunk of the systemic arteries" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "aortic completeness" RELATED []
relationship: part_of MT:0007044 ! aorta integrity

[Term]
id: MT:0007047
name: aorta configuration
namespace: Trait.ontology
def: "any measurable characteristic of the arrangement of the main trunk of the systemic arteries" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "aortic configuration" RELATED []
relationship: part_of MT:0000272 ! aorta morphology

[Term]
id: MT:0007048
name: aorta elastic tissue composition
namespace: Trait.ontology
def: "any measurable or observable characteristic pertaining to the types and ratios of substances within the slender connective tissue fiber in aortic tissue characterized by great elasticity" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "aortic elastic fiber composition" RELATED []
relationship: part_of MT:0003211 ! aorta elastic tissue morphology

[Term]
id: MT:0007049
name: aorta elastic tissue integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the slender connective tissue fiber in aortic tissue characterized by great elasticity" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "aortic elastic fiber integrity" RELATED []
is_a: MT:0000101 ! blood vessel elastic tissue integrity
relationship: part_of MT:0003211 ! aorta elastic tissue morphology

[Term]
id: MT:0007050
name: aortic arch completeness
namespace: Trait.ontology
def: "any measurable or observable characteristic pertaining to the wholeness of the portion of the descending aorta proceeding from the arch of the aorta and extending to the diaphram" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0000099 ! aotic arch integrity

[Term]
id: MT:0007052
name: aortic arch configuration
namespace: Trait.ontology
def: "any measurable characteristic of the arrangement of the portion of the descending aorta proceeding from the arch of the aorta and extending to the diaphram" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0004113 ! aortic arch morphology

[Term]
id: MT:0007053
name: coronary artery integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the arteries that branch from the aorta to supply blood to the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
is_a: MT:0003410 ! artery integrity
relationship: part_of MT:0004111 ! coronary artery morphology

[Term]
id: MT:0007054
name: pulmonary artery integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the artery that arises from the right ventricle and conveys unaerated blood to the lungs" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
is_a: MT:0003410 ! artery integrity
relationship: part_of MT:0000484 ! pulmonary artery morphology

[Term]
id: MT:0007055
name: kidney blood vessel integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the blood vessel network of the organ of excretion" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "integrity of the renal vasculature" RELATED []
synonym: "renal vascular integrity" RELATED []
is_a: MT:0000088 ! blood vessel integrity
relationship: part_of MT:0000530 ! kidney blood vessel morphology

[Term]
id: MT:0007056
name: lung blood vessel integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the blood vessels of the organ of respiration" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
synonym: "integrity of the pulmonary vasculature" RELATED []
synonym: "lung vascular integrity" RELATED []
relationship: part_of MT:0004007 ! lung blood vessel morphology

[Term]
id: MT:0007057
name: vascular smooth muscle integrity
namespace: Trait.ontology
def: "any measurable characteristic pertaining to the the structural completeness or structural soundness of the nonstriated, involuntary muscle tissue of the blood vessels" [RGD:ms "Mary Shimoyama, Rat Genome Database Program Manager"]
relationship: part_of MT:0000088 ! blood vessel integrity
relationship: part_of MT:0005592 ! blood vessel smooth muscle morphology

[Term]
id: MT:0007058
name: blood-brain barrier function
namespace: Trait.ontology
is_a: MT:0000249 ! blood vessel physiology

[Term]
id: MT:0007059
name: blood-cerebrospinal fluid barrier function
namespace: Trait.ontology
is_a: MT:0000249 ! blood vessel physiology

[Term]
id: MT:0007060
name: electrical depolarization of atria
namespace: Trait.ontology
is_a: MT:0003137 ! impulse conducting system function

[Term]
id: MT:0007061
name: electrical depolarization of ventricle
namespace: Trait.ontology
is_a: MT:0003137 ! impulse conducting system function

[Term]
id: MT:0007062
name: time between ventricular depolarization and repolarization
namespace: Trait.ontology
is_a: MT:0003137 ! impulse conducting system function

[Term]
id: MT:0007063
name: atrial muscle contractility
namespace: Trait.ontology
is_a: MT:0002972 ! cardiac muscle contractility

[Term]
id: MT:0007064
name: excitation-contraction coupling
namespace: Trait.ontology
is_a: MT:0003137 ! impulse conducting system function

[Term]
id: MT:0007065
name: time between atrial depolarization and ventricle depolarization
namespace: Trait.ontology
is_a: MT:0003137 ! impulse conducting system function

[Term]
id: MT:0007066
name: arterial elasticity trait
namespace: Trait.ontology
is_a: MT:0000249 ! blood vessel physiology

[Term]
id: MT:0007067
name: carotid-brachial pulse wave velocity
namespace: Trait.ontology
is_a: MT:0007066 ! arterial elasticity trait

[Term]
id: MT:0007068
name: carotid-femoral pulse wave velocity
namespace: Trait.ontology
is_a: MT:0007066 ! arterial elasticity trait

[Term]
id: MT:0007069
name: carotid-radial pulse wave velocity
namespace: Trait.ontology
is_a: MT:0007066 ! arterial elasticity trait

[Term]
id: MT:0007070
name: forward pressure wave amplitude
namespace: Trait.ontology
is_a: MT:0007066 ! arterial elasticity trait

[Term]
id: MT:0007071
name: reflected pressure wave amplitude
namespace: Trait.ontology
is_a: MT:0007066 ! arterial elasticity trait

[Term]
id: MT:0007072
name: left ventricle internal dimension
namespace: Trait.ontology
def: "any measurable characteristic of the spacial extent of the inside of the left lower chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0002753 ! left ventricle size

[Term]
id: MT:0007073
name: left ventricle internal diameter, diastole
namespace: Trait.ontology
is_obsolete: true

[Term]
id: MT:0007074
name: left ventricle internal diameter, systole
namespace: Trait.ontology
is_obsolete: true

[Term]
id: MT:0007075
name: left ventricle wall thickness
namespace: Trait.ontology
def: "cross sectional width from the interior to the exterior edge of the wall of the left lower chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0003921 ! left ventricle morphology

[Term]
id: MT:0007076
name: left atrium dimension
namespace: Trait.ontology
def: "any measurable characteristic of the spacial extent of the left upper lower chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "left atrial dimension" RELATED []
relationship: part_of MT:0000012 ! left atrium size

[Term]
id: MT:0007077
name: right atrium dimension
namespace: Trait.ontology
def: "any measurable characteristic of the spacial extent of the left upper lower chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0000005 ! right atrium size

[Term]
id: MT:0007078
name: right ventricle internal dimension
namespace: Trait.ontology
def: "any measurable characteristic of the spacial extent of the inside of the right lower chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "right ventricular internal dimension" RELATED []
relationship: part_of MT:0002754 ! right ventricle size

[Term]
id: MT:0007079
name: right ventricle internal diameter, diastole
namespace: Trait.ontology
is_obsolete: true

[Term]
id: MT:0007080
name: right ventricle internal diameter, systole
namespace: Trait.ontology
is_obsolete: true

[Term]
id: MT:0007081
name: atrium septum morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the wall between the upper chambers of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "atrial septal morphology" RELATED []
synonym: "atrial septum morphology" RELATED []
relationship: part_of MT:0003105 ! heart atrium morphology
relationship: part_of MT:0006113 ! heart septum morphology

[Term]
id: MT:0007082
name: ventricle septum morphology
namespace: Trait.ontology
def: "any measurable or observable characteristic related to the shape, structure, color or pattern of the wall between the lower chambers of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "interventricular septal thickness" RELATED []
synonym: "ventricle septal morphology" RELATED []
synonym: "ventricular septal morphology" RELATED []
synonym: "ventricular septum morphology" RELATED []
relationship: part_of MT:0005294 ! heart ventricle morphology
relationship: part_of MT:0006113 ! heart septum morphology

[Term]
id: MT:0007083
name: ventricle septum completeness
namespace: Trait.ontology
def: "any measurable or observable characteristic pertaining to the wholeness of the wall between the lower chambers of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "interventricular septal completeness" RELATED []
synonym: "ventricular septal completeness" RELATED []
relationship: part_of MT:0000281 ! ventricle septum integrity

[Term]
id: MT:0007084
name: ventricle septum configuration
namespace: Trait.ontology
def: "any measurable or observable characteristic of the arrangement of the wall separating the lower chambers of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "interventricular septal configuration" RELATED []
synonym: "ventricular septal configuration" RELATED []
relationship: part_of MT:0007082 ! ventricle septum morphology

[Term]
id: MT:0007086
name: ventricle septum thickness
namespace: Trait.ontology
synonym: "interventricular septal thickness" RELATED []
synonym: "ventricular septal thickness" RELATED []
relationship: part_of MT:0007082 ! ventricle septum morphology

[Term]
id: MT:0007087
name: left ventricle posterior wall thickness
namespace: Trait.ontology
def: "cross sectional width from the interior to the exterior edge of the wall closest to the back of the left ventricle" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
is_a: MT:0007075 ! left ventricle wall thickness

[Term]
id: MT:0007088
name: right ventricle wall thickness
namespace: Trait.ontology
def: "cross sectional width from the interior to the exterior edge of the wall of the right lower chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
relationship: part_of MT:0003920 ! right ventricle morphology

[Term]
id: MT:0007089
name: right ventricle posterior wall thickness
namespace: Trait.ontology
def: "cross sectional width from the interior to the exterior edge of the wall closest to the back of the right lower chamber of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
is_a: MT:0007088 ! right ventricle wall thickness

[Term]
id: MT:0007090
name: aorta size
namespace: Trait.ontology
def: "the physical dimensions, proportions, magnitude, or extent of the main trunk of the systemic arteries" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "aortic size" RELATED []
relationship: part_of MT:0000272 ! aorta morphology

[Term]
id: MT:0007091
name: aorta root diameter
namespace: Trait.ontology
def: "length of the straight line segment passing through the center of the portion of the aorta attached to the atrioventricular fibrous rings and myocardium" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
synonym: "aortic root diameter" RELATED []
relationship: part_of MT:0007090 ! aorta size

[Typedef]
id: is_a
name: is a
namespace: Trait.ontology
subset: slim_cattle
subset: slim_chkn
subset: slim_pig

[Typedef]
id: part_of
name: part_of
namespace: Trait.ontology
subset: slim_cattle
subset: slim_chkn
subset: slim_pig
is_transitive: true